LOCUS       DAVLDI010000001        77987 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLDI010000001 DAVLDI010000000
VERSION     DAVLDI010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 77987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77987
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.001"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(52..1389)
                     /locus_tag="VXD01_000001"
     CDS             complement(52..1389)
                     /locus_tag="VXD01_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV0600472.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(1399..1665)
                     /locus_tag="VXD01_000002"
     CDS             complement(1399..1665)
                     /locus_tag="VXD01_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV0600473.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(1930..2316)
                     /gene="rplQ"
                     /locus_tag="VXD01_000003"
     CDS             complement(1930..2316)
                     /gene="rplQ"
                     /locus_tag="VXD01_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV0600474.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(2328..3263)
                     /locus_tag="VXD01_000004"
     CDS             complement(2328..3263)
                     /locus_tag="VXD01_000004"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV0600475.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(3306..3689)
                     /gene="rpsK"
                     /locus_tag="VXD01_000005"
     CDS             complement(3306..3689)
                     /gene="rpsK"
                     /locus_tag="VXD01_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV0600476.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(3707..4072)
                     /gene="rpsM"
                     /locus_tag="VXD01_000006"
     CDS             complement(3707..4072)
                     /gene="rpsM"
                     /locus_tag="VXD01_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV0600477.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(4090..4206)
                     /gene="rpmJ"
                     /locus_tag="VXD01_000007"
     CDS             complement(4090..4206)
                     /gene="rpmJ"
                     /locus_tag="VXD01_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV0600478.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(4231..4449)
                     /gene="infA"
                     /locus_tag="VXD01_000008"
     CDS             complement(4231..4449)
                     /gene="infA"
                     /locus_tag="VXD01_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV0600479.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(4566..5204)
                     /locus_tag="VXD01_000009"
     CDS             complement(4566..5204)
                     /locus_tag="VXD01_000009"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV0600480.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHCVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            complement(5355..6665)
                     /gene="secY"
                     /locus_tag="VXD01_000010"
     CDS             complement(5355..6665)
                     /gene="secY"
                     /locus_tag="VXD01_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV0600481.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(6678..7118)
                     /gene="rplO"
                     /locus_tag="VXD01_000011"
     CDS             complement(6678..7118)
                     /gene="rplO"
                     /locus_tag="VXD01_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV0600482.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(7263..7487)
                     /gene="rpmD"
                     /locus_tag="VXD01_000012"
     CDS             complement(7263..7487)
                     /gene="rpmD"
                     /locus_tag="VXD01_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV0600483.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(7459..7953)
                     /gene="rpsE"
                     /locus_tag="VXD01_000013"
     CDS             complement(7459..7953)
                     /gene="rpsE"
                     /locus_tag="VXD01_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV0600484.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(7971..8327)
                     /gene="rplR"
                     /locus_tag="VXD01_000014"
     CDS             complement(7971..8327)
                     /gene="rplR"
                     /locus_tag="VXD01_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV0600485.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(8411..8947)
                     /gene="rplF"
                     /locus_tag="VXD01_000015"
     CDS             complement(8411..8947)
                     /gene="rplF"
                     /locus_tag="VXD01_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV0600486.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(9139..9537)
                     /gene="rpsH"
                     /locus_tag="VXD01_000016"
     CDS             complement(9139..9537)
                     /gene="rpsH"
                     /locus_tag="VXD01_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV0600487.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(9822..10091)
                     /gene="rpsN"
                     /locus_tag="VXD01_000017"
     CDS             complement(9822..10091)
                     /gene="rpsN"
                     /locus_tag="VXD01_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV0600488.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(10109..10651)
                     /gene="rplE"
                     /locus_tag="VXD01_000018"
     CDS             complement(10109..10651)
                     /gene="rplE"
                     /locus_tag="VXD01_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV0600489.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(10675..10980)
                     /gene="rplX"
                     /locus_tag="VXD01_000019"
     CDS             complement(10675..10980)
                     /gene="rplX"
                     /locus_tag="VXD01_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV0600490.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(11058..11426)
                     /gene="rplN"
                     /locus_tag="VXD01_000020"
     CDS             complement(11058..11426)
                     /gene="rplN"
                     /locus_tag="VXD01_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV0600491.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(11452..11712)
                     /gene="rpsQ"
                     /locus_tag="VXD01_000021"
     CDS             complement(11452..11712)
                     /gene="rpsQ"
                     /locus_tag="VXD01_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV0600492.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(11737..11943)
                     /locus_tag="VXD01_000022"
     CDS             complement(11737..11943)
                     /locus_tag="VXD01_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV0600493.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(11953..12366)
                     /gene="rplP"
                     /locus_tag="VXD01_000023"
     CDS             complement(11953..12366)
                     /gene="rplP"
                     /locus_tag="VXD01_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV0600494.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(12370..13023)
                     /gene="rpsC"
                     /locus_tag="VXD01_000024"
     CDS             complement(12370..13023)
                     /gene="rpsC"
                     /locus_tag="VXD01_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV0600495.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(13036..13380)
                     /gene="rplV"
                     /locus_tag="VXD01_000025"
     CDS             complement(13036..13380)
                     /gene="rplV"
                     /locus_tag="VXD01_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV0600496.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(13392..13673)
                     /gene="rpsS"
                     /locus_tag="VXD01_000026"
     CDS             complement(13392..13673)
                     /gene="rpsS"
                     /locus_tag="VXD01_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV0600497.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(13777..14610)
                     /gene="rplB"
                     /locus_tag="VXD01_000027"
     CDS             complement(13777..14610)
                     /gene="rplB"
                     /locus_tag="VXD01_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV0600498.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(14628..14924)
                     /locus_tag="VXD01_000028"
     CDS             complement(14628..14924)
                     /locus_tag="VXD01_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV0600499.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(14924..15547)
                     /gene="rplD"
                     /locus_tag="VXD01_000029"
     CDS             complement(14924..15547)
                     /gene="rplD"
                     /locus_tag="VXD01_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV0600500.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(15572..16198)
                     /gene="rplC"
                     /locus_tag="VXD01_000030"
     CDS             complement(15572..16198)
                     /gene="rplC"
                     /locus_tag="VXD01_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV0600501.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(16414..16722)
                     /gene="rpsJ"
                     /locus_tag="VXD01_000031"
     CDS             complement(16414..16722)
                     /gene="rpsJ"
                     /locus_tag="VXD01_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV0600502.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(16988..17605)
                     /locus_tag="VXD01_000032"
     CDS             complement(16988..17605)
                     /locus_tag="VXD01_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV0600503.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(17602..18192)
                     /gene="nrdG"
                     /locus_tag="VXD01_000033"
     CDS             complement(17602..18192)
                     /gene="nrdG"
                     /locus_tag="VXD01_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV0600504.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            complement(18185..18691)
                     /locus_tag="VXD01_000034"
     CDS             complement(18185..18691)
                     /locus_tag="VXD01_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0600505.1"
                     /translation="MELRRPRLADKETVLEMMTEFEKFQSPHDGGFWNTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVVFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            complement(18735..18875)
                     /locus_tag="VXD01_000035"
     CDS             complement(18735..18875)
                     /locus_tag="VXD01_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600506.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(18887..21094)
                     /gene="nrdD"
                     /locus_tag="VXD01_000036"
     CDS             complement(18887..21094)
                     /gene="nrdD"
                     /locus_tag="VXD01_000036"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV0600507.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKQEDYAWK
                     KAQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(21214..22752)
                     /locus_tag="VXD01_000037"
     CDS             complement(21214..22752)
                     /locus_tag="VXD01_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0600508.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(22789..22932)
                     /locus_tag="VXD01_000038"
     CDS             complement(22789..22932)
                     /locus_tag="VXD01_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600509.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(23010..24542)
                     /gene="cls"
                     /locus_tag="VXD01_000039"
     CDS             complement(23010..24542)
                     /gene="cls"
                     /locus_tag="VXD01_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV0600510.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(24688..25230)
                     /locus_tag="VXD01_000040"
     CDS             complement(24688..25230)
                     /locus_tag="VXD01_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV0600511.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            complement(25227..26477)
                     /locus_tag="VXD01_000041"
     CDS             complement(25227..26477)
                     /locus_tag="VXD01_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0600512.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLICQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KTLEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(26736..27041)
                     /locus_tag="VXD01_000042"
     CDS             complement(26736..27041)
                     /locus_tag="VXD01_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV0600513.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(27057..27476)
                     /gene="ruvX"
                     /locus_tag="VXD01_000043"
     CDS             complement(27057..27476)
                     /gene="ruvX"
                     /locus_tag="VXD01_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV0600514.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(27480..27746)
                     /locus_tag="VXD01_000044"
     CDS             complement(27480..27746)
                     /locus_tag="VXD01_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV0600515.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(27833..28402)
                     /locus_tag="VXD01_000045"
     CDS             complement(27833..28402)
                     /locus_tag="VXD01_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0600516.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            complement(28468..28866)
                     /gene="spx"
                     /locus_tag="VXD01_000046"
     CDS             complement(28468..28866)
                     /gene="spx"
                     /locus_tag="VXD01_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV0600517.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            complement(28998..30059)
                     /locus_tag="VXD01_000047"
     CDS             complement(28998..30059)
                     /locus_tag="VXD01_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0600518.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            complement(30052..32883)
                     /gene="uvrA"
                     /locus_tag="VXD01_000048"
     CDS             complement(30052..32883)
                     /gene="uvrA"
                     /locus_tag="VXD01_000048"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV0600519.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            complement(33372..33791)
                     /locus_tag="VXD01_000049"
     CDS             complement(33372..33791)
                     /locus_tag="VXD01_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0600520.1"
                     /translation="MTPEQVKEKLEGVKWINKEIKGLYLELETLEGGIIKKPTLSHSR
                     VQTSRENKTENNLISVLKLKEDTLQRIERLTEERMKISELIDKLANPLERSVLRLFYL
                     NDLVVSEVAEEIDRSNTTVYIIRQKAIEHLTGIVNGD"
     gene            complement(34998..35507)
                     /locus_tag="VXD01_000050"
     CDS             complement(34998..35507)
                     /locus_tag="VXD01_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600521.1"
                     /translation="MKQLAIEAITKPMKLRGISKGIAELDGQRLEIDLDSLMIDFGGE
                     SFELDRIAGTKGGNRYFFLCPDCGRRCRLLYKRYLYFSCGTCLDIHKHTLNRSKTDCQ
                     YYWELALKEARKVEPGWSPRRGGYMFDSFPERPKYMKQKRYYKHYQKFINYTRKGDSF
                     WLNGLSSLR"
     gene            complement(35578..36108)
                     /locus_tag="VXD01_000051"
     CDS             complement(35578..36108)
                     /locus_tag="VXD01_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600522.1"
                     /translation="MTLKTFSSKAKTFTFTYEFKDLDTALVAGHALLGYMTGTYCQPV
                     ISLTYKDKGTLVAEYVEDHKLNKTFKRICDSFKDYHKQPGEAEAFEERYKRERVLQLK
                     ESEDFESLLNKVTDYELELLDYADRLLSDKPIPMDSMTAFATLEMLGDESISLLQKLD
                     VEGEYKGLAGYTEHLK"
     gene            complement(36192..36359)
                     /locus_tag="VXD01_000052"
     CDS             complement(36192..36359)
                     /locus_tag="VXD01_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600523.1"
                     /translation="MKVKLFEYTRRWEKEDFEKEIDDFMATVEVLDVKFSGTPSSESF
                     NSVATVLVLYR"
     gene            complement(36722..38191)
                     /locus_tag="VXD01_000053"
     CDS             complement(36722..38191)
                     /locus_tag="VXD01_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEV0600524.1"
                     /translation="MEQEHPPRTMKELENRIFKAGEEWRAEHTETKVNENTGDVTEKV
                     AMPQTFTVAKILSEIVTFTFISKSNIPDYSLLYIYDLDEGIYTASNDLFNLLCKTFDV
                     RIKPREWPQIKLMVRTLAKIRKPLESANLIPVQNGIINLETKELLPFSPKYVITSKIS
                     TAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINPNHTRNKFAIFYG
                     DGNNGKGTFQRFLINLIGESNISALKPAQFAEKHNLETLVGKVCNIGDEAPNEYLKNP
                     SDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVPFNA
                     DFNGEKEKPWIKNEFLANKEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEDNDYL
                     LSWVKHEYMEKGWHELDVVPVFIVTRSLKHYAEDMGIPKPNVYGAGKETIKHLQQLTP
                     NRYSLRKKRVSPEDFEKLEAWDVDKIKMRTPQHSITKQE"
     gene            complement(38244..39110)
                     /locus_tag="VXD01_000054"
     CDS             complement(38244..39110)
                     /locus_tag="VXD01_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEV0600525.1"
                     /translation="MTIYEAKGFQSNLVYPFDKIEPFQYIERFKPLVVPEGADIEEYK
                     RTQAPYCISGKVTPEKHGSYKRNNSSLIYRDLIFLDYDDIQGTSEGFIKAISSALFGY
                     SYILYPTIKHSLEKPRFRLVVKPDNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPASYQKIVEHGLDYPVPQTTAEPVKQNAASLPYTPRPSGQKSMTMRIIDT
                     LFNGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTF
                     SSIARAEYRKRG"
     gene            complement(39245..39526)
                     /locus_tag="VXD01_000055"
     CDS             complement(39245..39526)
                     /locus_tag="VXD01_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV0600526.1"
                     /translation="MFSLSRESEQDLAHGILEVVERYLEARDTVKPRLTGLISAQEVM
                     DELDIKYMTLQKWEKAGLRRYQPPLEDTRKIYYKISDIWKFLGVENGKV"
     gene            complement(39519..39860)
                     /locus_tag="VXD01_000056"
     CDS             complement(39519..39860)
                     /locus_tag="VXD01_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0600527.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGAEISLITKLAERTVQDIISR
                     LITRHSVPIVGVRHGTFRGYFIPANKEELLDGAKAFYNQVQEEQKRLTVLLNADLESY
                     KETLKEVGGYV"
     gene            complement(39857..40072)
                     /locus_tag="VXD01_000057"
     CDS             complement(39857..40072)
                     /locus_tag="VXD01_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600528.1"
                     /translation="MNELDLTNTQSVIFMVVLIGLLLYLNHRDRKKSAQFERENQQRI
                     ETPSEDLSPDYGRYIQLAGVRVYGGTE"
     gene            complement(40074..40274)
                     /locus_tag="VXD01_000058"
     CDS             complement(40074..40274)
                     /locus_tag="VXD01_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600529.1"
                     /translation="MTLNLDNMTQAEFDEVMAEIKEKRPNLFQFIADFVDRKVSTEEV
                     DEYLKMKHEKQVEFIKNYQARA"
     gene            complement(40271..40723)
                     /locus_tag="VXD01_000059"
     CDS             complement(40271..40723)
                     /locus_tag="VXD01_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600530.1"
                     /translation="MTETTYENLTRHIDRISAEMREIGEKNGLSRLSLLANQTKFIKE
                     NLHRLLWIELPELNDSHKIEAVSKSTTGMFFHAGIFEMDAMRQAFFKRQAMHFFDNEA
                     EQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ"
     gene            complement(41095..41721)
                     /locus_tag="VXD01_000060"
     CDS             complement(41095..41721)
                     /locus_tag="VXD01_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEV0600531.1"
                     /translation="MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESF
                     GKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVKEFKKNLVKAFFEMREELS
                     KFRMQRALEKPKRKTLHDSIETWEAKPKHAHSTMNNLLLKAVTDMNAKQLREERGGYN
                     GIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSA"
     gene            complement(41737..41966)
                     /locus_tag="VXD01_000061"
                     /pseudo
     CDS             complement(41737..41966)
                     /locus_tag="VXD01_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            42119..42832
                     /locus_tag="VXD01_000062"
     CDS             42119..42832
                     /locus_tag="VXD01_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0600532.1"
                     /translation="MAKNSPQDLKNREYFSNNLNRVMKEKGIRQIDLHNALEIPKSTI
                     TGYVKGRSMPTSGNLQKLADYLGVKKSDLDPRFSDKDVYKEFLYMLDKQLDEEKYLVK
                     NVSKDKIFQKVKEREKRDKEIIELAKSKNFPISPEEFLTTITESLNEYNPKDNYEVLN
                     ALALKTSNILFWLDIVFQKTSSEFYIVFEDKEFNQEYYNKLYKKFENLFEEIKSLALQ
                     EAKKDKENLDDFALLWGID"
     gene            42993..44507
                     /locus_tag="VXD01_000063"
     CDS             42993..44507
                     /locus_tag="VXD01_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEV0600533.1"
                     /translation="MRKYDIPKLLLSGENQGVEFKEAKNSFPKDGMKTICSFANTNNG
                     LLILGVSENTKNKDFYISGVNDPDKVLDELYSLLNNPNKINRNVINEESVEVVNIKGK
                     EIVIIPVNKVDYKDKPIYLNDNIASTYFRQGTGDFRCSQEQINSMLRDSAKESFDSTL
                     IQDFSILDLDTETIKLYREKFDNINAEHPFSKLDNEQFLIKINALRRDRKDDKIKPTV
                     AGLLIFGTHNSIKEFIPHYNVEYVLKEFSENNRFKDRVIYDGTWGEDNLFNFFYLVIE
                     KLYLTLNDNSNIQENSMNRIGISKLRIAIREAFINSLIHSDYKSEKGIMIIRYPDRYI
                     FTNGGTLRIDIKDFFSGAHSDPRNYLIQEIFRFLNLCEKAGTGIPKIMEAVKESHLKY
                     PNLRTELDSVEFTLWDTSLIDNLDIDNEYEKKILELIIEHRFVTREALEEKLKIHKNT
                     ILKYLKKLVEKQAIDKFKSGRQYVYFITQNQDPEFQKYNHINAMYSLLEEIKRK"
     gene            44592..45758
                     /locus_tag="VXD01_000064"
     CDS             44592..45758
                     /locus_tag="VXD01_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0600534.1"
                     /translation="MKITEVIKKDGSKVYRANVYLGVDQVTGKKVKTKVTGRTQKEVK
                     QKANQEKIAFQKAGSTRQKAVTIKNYQELATLWLESYKNTVKPNTQGNVKKLIDNHIL
                     PIFGAYKLDKLTTPLIQSIINELADKTNRGEKAAFLHYDKIHALNKRILQYGVTMQAI
                     PSNPARDVVLPRNTQKAKRKKVKHFENQELKKFLGYLDNLDTHRYRYYYETTLYKFLL
                     ATGCRINEALALSWSDIDLDNAVVHITKTLNRDIEINSPKSKASYRDIDIDQATVSML
                     KQYKLRQTKEAWKIGQRERVVFSDFIHEYPSSSRLKRRLQTHFKRADVPNIGFHGFRH
                     THASLLLNSGIPYKELQYRLGHSTLSMTMDIYSHLSKENAKKAVSFYETALKAL"
     gene            45919..46863
                     /locus_tag="VXD01_000065"
     CDS             45919..46863
                     /locus_tag="VXD01_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0600535.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            46875..47558
                     /locus_tag="VXD01_000066"
     CDS             46875..47558
                     /locus_tag="VXD01_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV0600536.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGVALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            47813..48844
                     /locus_tag="VXD01_000067"
     CDS             47813..48844
                     /locus_tag="VXD01_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV0600537.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDAYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(48981..49658)
                     /locus_tag="VXD01_000068"
     CDS             complement(48981..49658)
                     /locus_tag="VXD01_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0600538.1"
                     /translation="MMSNKNKGILIFVILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(49655..50218)
                     /locus_tag="VXD01_000069"
     CDS             complement(49655..50218)
                     /locus_tag="VXD01_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV0600539.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQSPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKCLK"
     gene            complement(50228..50821)
                     /gene="ruvA"
                     /locus_tag="VXD01_000070"
     CDS             complement(50228..50821)
                     /gene="ruvA"
                     /locus_tag="VXD01_000070"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV0600540.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     regulatory      50978..51092
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            51226..52326
                     /gene="ribD"
                     /locus_tag="VXD01_000071"
     CDS             51226..52326
                     /gene="ribD"
                     /locus_tag="VXD01_000071"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV0600541.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     gene            52311..52946
                     /gene="ribE"
                     /locus_tag="VXD01_000072"
     CDS             52311..52946
                     /gene="ribE"
                     /locus_tag="VXD01_000072"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV0600542.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            52966..54171
                     /locus_tag="VXD01_000073"
     CDS             52966..54171
                     /locus_tag="VXD01_000073"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV0600543.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERSGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            54172..54639
                     /locus_tag="VXD01_000074"
     CDS             54172..54639
                     /locus_tag="VXD01_000074"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV0600544.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(54964..56913)
                     /gene="mutL"
                     /locus_tag="VXD01_000075"
     CDS             complement(54964..56913)
                     /gene="mutL"
                     /locus_tag="VXD01_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV0600545.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            57269..57709
                     /locus_tag="VXD01_000076"
     CDS             57269..57709
                     /locus_tag="VXD01_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0600546.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            57706..58164
                     /locus_tag="VXD01_000077"
     CDS             57706..58164
                     /locus_tag="VXD01_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV0600547.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(58382..59335)
                     /locus_tag="VXD01_000078"
     CDS             complement(58382..59335)
                     /locus_tag="VXD01_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV0600548.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNKNKSNREIAGLLGKAPQTI
                     HTEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            59719..60981
                     /locus_tag="VXD01_000079"
     CDS             59719..60981
                     /locus_tag="VXD01_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV0600549.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(61274..61744)
                     /gene="nrdI"
                     /locus_tag="VXD01_000080"
     CDS             complement(61274..61744)
                     /gene="nrdI"
                     /locus_tag="VXD01_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV0600550.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(61822..62355)
                     /locus_tag="VXD01_000081"
     CDS             complement(61822..62355)
                     /locus_tag="VXD01_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0600551.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            complement(62407..63693)
                     /locus_tag="VXD01_000082"
     CDS             complement(62407..63693)
                     /locus_tag="VXD01_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0600552.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFAIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVSITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFDQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            complement(63705..65351)
                     /locus_tag="VXD01_000083"
     CDS             complement(63705..65351)
                     /locus_tag="VXD01_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0600553.1"
                     /translation="MKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            complement(65353..65967)
                     /locus_tag="VXD01_000084"
     CDS             complement(65353..65967)
                     /locus_tag="VXD01_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0600554.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            66102..66671
                     /locus_tag="VXD01_000085"
     CDS             66102..66671
                     /locus_tag="VXD01_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV0600555.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPHFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            complement(66700..67392)
                     /locus_tag="VXD01_000086"
     CDS             complement(66700..67392)
                     /locus_tag="VXD01_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0600556.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(67394..68455)
                     /locus_tag="VXD01_000087"
     CDS             complement(67394..68455)
                     /locus_tag="VXD01_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV0600557.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            complement(68448..69821)
                     /locus_tag="VXD01_000088"
     CDS             complement(68448..69821)
                     /locus_tag="VXD01_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV0600558.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEDRMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            complement(69921..70775)
                     /locus_tag="VXD01_000089"
     CDS             complement(69921..70775)
                     /locus_tag="VXD01_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0600559.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSTNKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            complement(70929..71759)
                     /locus_tag="VXD01_000090"
     CDS             complement(70929..71759)
                     /locus_tag="VXD01_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0600560.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            complement(71862..72185)
                     /locus_tag="VXD01_000091"
     CDS             complement(71862..72185)
                     /locus_tag="VXD01_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV0600561.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            complement(72175..72831)
                     /locus_tag="VXD01_000092"
     CDS             complement(72175..72831)
                     /locus_tag="VXD01_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV0600562.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTDLGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            72902..72979
                     /locus_tag="VXD01_000093"
                     /pseudo
     CDS             72902..72979
                     /locus_tag="VXD01_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(73285..74511)
                     /locus_tag="VXD01_000094"
     CDS             complement(73285..74511)
                     /locus_tag="VXD01_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0600563.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLKHTISIKTALYASLVTQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(74583..75248)
                     /locus_tag="VXD01_000095"
     CDS             complement(74583..75248)
                     /locus_tag="VXD01_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0600564.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            complement(75316..75516)
                     /locus_tag="VXD01_000096"
     CDS             complement(75316..75516)
                     /locus_tag="VXD01_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV0600565.1"
                     /translation="MLNLQFAETMELTEAELETVYGGELGYNAVIPGGSWGGLGTSWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            complement(75802..76665)
                     /locus_tag="VXD01_000097"
     CDS             complement(75802..76665)
                     /locus_tag="VXD01_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0600566.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRKVVDRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKRYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFLYIPIFE
                     AELESMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFTQSLQVLENPQLTSLFE
                     LRFQQYKELID"
     gene            complement(77060..>77987)
                     /locus_tag="VXD01_000098"
     CDS             complement(77060..>77987)
                     /locus_tag="VXD01_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV0600567.1"
                     /translation="TDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKLTVPFGFSNK
                     LKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGRKIAELFLSISTHSTAN
                     IKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPRIG
                     KFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKPK
                     IVGIYKLGMKYNSDNYKESAILSIINELLIVGIKILVYEPNLNVSIDNVIFEKNFELF
                     TKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
BASE COUNT        22835 a        16842 c        14482 g        23828 t
ORIGIN      
        1 tatagtatac acatctaatc ttaaatagaa cttaaaattt ctcctatttt cttaattttt
       61 aaaactatga attggtgctg ggatttgtcc accgcgagag atgaagtcga cagacgaagc
      121 cccattaacc ttcataacgg gtgcagttcc taatagacca ccaaactcaa tcatatcgcc
      181 ttctcttcct ttgggaatga tacgaacagc tgttgttttc atgttgataa caccgattgc
      241 tgcttcatcc gcaatcatag ccgcaatagt ttcagcaggc gtatcttctg ggatggcaat
      301 catatccaat ccaacagaac agatagccgt catagcttct agtttttcta aattaagaga
      361 gccattttgc actgcagcaa tcattccttc atcctcagaa acagggataa aggcaccaga
      421 tagaccaccg acctggttac aggccatcac tccacccttt ttaacttggt cgttcaagag
      481 ggccaaggca gctgtcgttc catgcgtgcc aactgtttct agccccattt cctcaaggac
      541 acgtgccaca gagtctccaa ccgcaggggt tggtgccaaa ctcaagtcca caataccaaa
      601 ctccacaccc agtctctcac tggccatttg accaaccaat tgaccgatac gagtgatttt
      661 aaaggcagtt ttcttaactg tttcggctac tacatcaaag ctctgtccac gaactttttc
      721 caaagcacgt ttcacaacac caggaccaga aactccgaca ttgatgataa catctgcttc
      781 cccaacacca tgaaaggcac ccgccataaa tggattgtcc tcaacagcat tagcgaatac
      841 aaccaacttg gccactccca tatctgaaag atttgctgtt tccttgataa ttcgtcccat
      901 atctgccaca gccgtcatat taataccaga cttggttgag ccgatattga ctgacgagca
      961 gaccttatcc gtctcagcca aagcgcgagg aatggaattg atgagaatct catctccctt
     1021 ttgataacct ttttgtacta aggcagaaaa accaccaata aagtccacac caatctcttt
     1081 cgcagcctta tcaagcgctt ttgccagaac cacgtagtcc gtcgcatctg tcgctgcccc
     1141 aatcagagaa ataggtgtca ccgatacacg cttattaacg ataggaattc ccaactcagc
     1201 cgcaatttca tcaccaacag ctactaaatt agccgccttt gtcgtaattt tttgatagat
     1261 tttctccgca gcacgattga tatttggatc gatacagtcc aaaagagaaa tccccatggt
     1321 aatggttcta atatcgaagt tttgctcctc aatcatggcg atggtttcag taacttgtct
     1381 aatatccatg atgacctcct agatattata catagcttcg aaaatcgctg cactctgaat
     1441 attgattttt acattcaaag tttgcccaaa agcttcaaat tcattacgaa gataggtaaa
     1501 atcttgcttt tcatcactag atacaacagc catcatcgta aaatattcat ccaatacagt
     1561 ttgagagata tcgtcaatat tcaatcctaa ttctgcaatt ttaccagaaa cacctgcaac
     1621 aattccagat ttatctttac caacaacagt tataatcgct ttcataagta aactccaatt
     1681 cttcttaaaa taagaaacct taacattaaa caggattctt ttcaaatagt atagcataat
     1741 tctaacgaaa atactcaaaa acgcctgctt acgaagttgt tcttaagaaa aaaacaattt
     1801 cgtaaacaag cgtctactat cccaacttat gatgagtgtt cccgctagga ccgaaatcct
     1861 agcggtagac cagagctaga ctaagagcac aagactccat catcataaca ctcaacaaaa
     1921 ttgatgattt tatactaatt cgatgatcgc cattggcgct gcatcaccac gacgtggttc
     1981 agttttaagg atacgagtgt atccaccgtt acgttcagca taacgaggtg cgatttctga
     2041 gaacaatttt tgaagtgctg tagtagaagt gtacttatca gttgcttcat catagttttc
     2101 agatgcgatt tcattacgta cgaaagcagc tgcttgacga cgtgcatgca aatcaccacg
     2161 tttacctaga gtaatcattt tttcaacagt tttacggatt tctttagcac gagcttcagt
     2221 tgtcacgatt gattcgttga tcaaaaggtc agttgtcaaa tcgcgaagca ttgctttacg
     2281 ttgtgagcta gtgcgtccta gtttacggta agccatgtat tcctccttta tttatctttt
     2341 aatccaagac ccaaatcaat gagtttgagt ttcacttctt ccaaactctt gcgtccaaga
     2401 tttcgtactt tcatcatctc tgcttcagat ttttctgtca aatcatgcac agtattgata
     2461 ccggcacgtt ttaaacagtt gtatgaacgc acagacaagt ccagttcctc aatcgtacga
     2521 tctaaaatac ggtcgtcaga ttcagtatca gcttctttca tcacttcagt tgacttagca
     2581 atctcagtaa gatttgtaaa caaatcaaga tgttctgtca aaatacgtgc tgaaagccct
     2641 aaagcatctt ctggaataat tgttccattt gtcaagattt caagggttaa tttgtcgaaa
     2701 ccatcattgc tacctacacg agcaggttcc acttgatagt tgacttttgt aactggtgta
     2761 taaatagaat ctacagcaag tgttccaact ggtgcattat cctttttatt ttcatcagca
     2821 ggtacatatc cacgaccact gttaacagtc atagtcgctt ttagagaaga accttcaccg
     2881 attgtaaaga gataatgatc tggatttaca atttcaatat cgctatctgt caaaatgtca
     2941 ccagctgtta cttcagcagg accttcaaca tccagttcga tgattttttc gtcttcaacg
     3001 tacgatttca ctgcaattcc tttaatgttc agaatgattt gcatcacgtc ttcacgaaca
     3061 cctggaactg tgtcaaactc atgtaacaca ccatcaatgt tgatagatgt cacagctgct
     3121 cctggtagag aagctagaag tacacgacga agagagttac caagagttgt accgtagcca
     3181 cgttcaagtg gttcgattac aaacttgcca taatctttat tttcatcaat ttttgttata
     3241 tttggttttt caaactcgat catttagtta ctccctctta aacgaaaagc agtgtaatgc
     3301 gatgattata cacggcgacg ttttggagga cgagcaccat tgtgtggcac tggagtcaca
     3361 tcacgaattg ctgttacttc aagaccagcg gcagcaagcg cacgaatagc tgactcacga
     3421 ccagaacctg gaccttttac agtaacttca actgatttaa gaccgtgttc ttgtgcagat
     3481 ttagcagcag cttcagaagc catttgagca gcgaatggtg tagatttacg agaacctttg
     3541 aaaccaagag caccagctga tgaccaagca attgcattac catgcacatc agtaatcata
     3601 acaatagtgt tattaaatgt agcgtgaata tgagcaatac cagattcgat attctttttc
     3661 acacgacgtt tacgtgttgg tttagccaag acttttacct cctatattat tttttcttac
     3721 cagcaatcgc aacagcttta cctttacgag tgcgagcgtt gtttttagta ttttgtccac
     3781 ggacaggaag tccacgacgg tgacggatac cacggtatga accgatttcc atcaaacgtt
     3841 tgatgttcaa gtttacttca cgacgaaggt caccttcaac tttgattgca tccacttcac
     3901 gacggatagc atcttcttga tctgatgtaa gatcacgtac acgaacatct tctgagattc
     3961 cagcagcagc caaaattttc ttagatgttg caagtccgat accataaaca taagtcaatg
     4021 agattactac gcgtttgtca tttggaatat caactccagc aatacgagcc atgttttctc
     4081 ctttctatct tatccttgac gttgtttgtg ttttggattt gctgggcaaa ttaccataac
     4141 acgaccatta cgacgaataa ctttacagta ttcgcaaatt ggtttgaccg atggtcttac
     4201 tttcatttct tatccctcca agtttttcga ttatttaaag cggtaagtga tacgtccacg
     4261 tgtcaagtca tatggactca tttcgacagt aacacgatct cccgctaaaa tacgaatata
     4321 gtttttacga attttaccag aaactgttgc taaaatctga tgtccatttt caagttcaac
     4381 cgtaaacatt gcattcggca ttgtatcaac tactttgcct tcaacttcaa tcacatcgtc
     4441 ttttgccacg caaaagcacc tccataaatt tcgattcgat gcctctagac acagagacaa
     4501 caattataag tcagactatc tcagtataac atttgtagcg gatttttgca agtgtgaaaa
     4561 acgctttatt tcaaatttgt caatactttt tcaatatctg agaagacatc attgatatct
     4621 tgattacctt cgatgtcatg aaccaaacct ttggcacggt agtgagcaat gattggttct
     4681 ccttgagcaa tattaacatc caaacgacgt tttactgtct caggcttatc atcttcacgt
     4741 tggtagtaat cttcttcttt atagtcaact ggtgggttaa agaccttgtg gaaagtttct
     4801 ccagttacgc agtggatgat acggccactc aaacgttcca agaggctgtc agggttcact
     4861 tcaatattga taataccttc tagttcaatg ccaagttcag ccaatgtttt gtccaaggca
     4921 tgagcttgtt caattgtacg tgggtaacca tccaataaga atcctgtttc tttaatatca
     4981 tcttgtgaaa ggcgttcttt tacgattcca tttgtaactt cgtcaggaac caattcaccc
     5041 ttgtcaatat atgacttagc aagaacaccc atttcagttt gatttgccat tgcagcgcgg
     5101 aacatatcac ctgttgagat atgtgcaaca tggaattgtt ctacgatttt tgctgcttga
     5161 gttcccttac ctgcaccagg taagcccata atcaaaagat tcatgatttg atctccttat
     5221 tttattttta aatagaagca aaaagtcttt tcacccctat ttaaaaacaa aatagaagag
     5281 gggagatcca actcttacaa atgtcagagt ttaaacctcc actccctcag tatttactga
     5341 ttcagtaaat acttttattc tgttctgtcc atgaaaccaa catacttacg tttcaatagg
     5401 taaccttcca attgcttgat tccttcgata cctgtagaga taatgatcaa gagacttgtt
     5461 ccaccaaagg caacaacatc agaaagacca aatacatctt tagctgcaat cggtaaaatg
     5521 gaaatcacac caaggaagag ggaaccaaca gttgcaagac gacgaagaag tttagacata
     5581 tattcttctg tacctttacc aggacgaact ccatggatat aggcaccact cttttgtagg
     5641 ctctctgctg ctttttcagg attaatctgt acaaacgtat agaagaatgt aaagagaata
     5701 atcaacaaag catacatggc aataccagtt ggagaagtag ttgccaacat ctcttgtgct
     5761 acccttaccc aagcccaatc atgacctgtg gcactcaaaa actgaagaat agccgcaggc
     5821 gctgcagtaa tcgaactggc aaagataaca gggataactc cagcaggatt tacctttaac
     5881 ggaaggtaag agctagatgg agcaccttgt gcaaccttag tatattggat tggaattttg
     5941 tattctgctt gttgaacata agttgtaaag taaataatca acaatacagt aataatcaaa
     6001 atgattacga aaatgataga tgaagtgata cggctacttg ggacgttcac aaagtagtcc
     6061 acatagatgc cctgaatcat ctctggaatt gaagaaacaa tcccggcaaa gataatcatg
     6121 gaaacaccgt ttccgtatcc cttatctgta atttgctcac ccaaccaagt gacaatcata
     6181 ctaccagctg ttaagatgat accaatcgtc agaaaaactt gtggagttaa agcagtttta
     6241 atcaattgag ctccagccaa ggtattaaaa ccagctgtaa tcccgataga ttgcacaaaa
     6301 gcgagaacta gagcaatata acgagtagct tgattcaatt ttcttcgacc tacttcccct
     6361 tgtttacccc actctacaaa cttgggtaaa atatccattt gcaagagttg gacaacaata
     6421 gaagcggtga tatagggact aactcctaag gcaaaaatcg aaaagttttt tagggcattc
     6481 cccgacacca agctcaacat gtttaagaag gataatccac ttaaagcatt caagctattg
     6541 gcattcacac caggaactgt aatgctagtt ccgatacgaa agaccaaaac gataaaaatt
     6601 gtaaataaaa tttttgatcg aacctgcttg actttaagag cttctcttaa taatttaaaa
     6661 aacataggtc acctctctta gatgacttct actgaaccac ctttagcagt gatagcttct
     6721 tcagctgatt tagagaattt agctgctttc acagtcaatt tcttagtcaa ctcaccgtta
     6781 ccaagaattt taatacctga cttttcagct ttaacaattc ctgcttcgat aagaacaact
     6841 ggagttactt cagcaccatc ttcaaagacg ttcaattggt caaggttcac aattgcgtat
     6901 tctttagcgt tgatgttagt gaatccacgt tttggaagac gacggaacaa tggagtttgt
     6961 ccaccttcaa aaccaaggcg aactccgcca ccgctacgag ctttttgacc tttttgacca
     7021 cgaccagatg ttttaccgtt acctgatgaa gtaccacgac caacgcggtt acgtacttta
     7081 cgagaacctt ctgcaggttt caattcatga agtttcattt ttattttctc ctcttttgta
     7141 aaatgctagc gccgataagg gagaaaaggt tgtctccccc atcaactcgc ctatacgatg
     7201 tcatcataga tgactatatc tagttttagg ggatggtaca gtgcacatcc cctaaaactt
     7261 cattagttta cttcttcaac tgttactaag tgagatactg ctgtgatcat accacggata
     7321 gcagcgttat cttctttaat aacagagctg ttcaatttgc caagtccaag tgctacaaca
     7381 gttttacgtt gtgatggaat gcgtccgatt ggagacttag tcaaagtaat tttaatttga
     7441 gccattttat cccctttctt atgccaaatc agaaactgaa ataccacgaa gggcagcaat
     7501 ttcttcagcg cgtttcaatt gtttcaaacc ttcaacagtt gcacgaacaa tgttgattgg
     7561 agtgttagaa ccaagtgatt tagatgtaat atctgccaca cctgccaatt ccacaacggc
     7621 acgaactgca ccaccagcgg caactccaga accttctaca gcaggtttca acaatacttt
     7681 agctccaccg aattctgaaa gaacttcgtg tgggattgtt gttccaacca taggaacttc
     7741 gatcaagttt ttcttagcat catctactgc tttacggatt gcttctggaa cttcttgagc
     7801 tttaccagta ccaaatccta cgcgaccatt gtggtcacca acaacaacaa gagctgcgaa
     7861 acgaagacga cgtccacctt taacaacttt tgtaacacgg ttgacagcaa ctacgcgttc
     7921 ttctaattca actgcattgt ctttaaatgc cattttctag tgtcctccta ttagaatttc
     7981 aatccgtttt cacgagctgc atcagccaaa gctttcacac gtccgtgata tagatatcca
     8041 ccgcggtcga acaccacttc tgaaatacct ttagcgtttg cacgttctgc aacgagttta
     8101 ccgacagcaa cggcttgttc agttttagtt ccttttgaaa cttctttatc aagagttgaa
     8161 gcacttgcga gcgttacacc cgctacgtca tcaatcactt gagcgtagat gcctgtatta
     8221 gaacggaata cgttcaaacg tgggcgatca gcagttccag agagttttcc gcgaacgcga
     8281 cggtggcgtt tttggcggag tttgttttta tctggttttg aaatcacagt tttcacctct
     8341 ttagttttaa atcgtgtgct atgcacaaag ttggaaaata ggttggtggt tgatgatcaa
     8401 ccactcaaca ttatttacct gttttacctt ctttacggcg aacgaattca ccaacgtaac
     8461 ggataccttt acctttatat ggttctggtg aacgaaggct acgtacgtaa gcagctgttt
     8521 gaccaactac ttcttttgaa attccgctaa caacgattgt tgttgggttt ggaagttcaa
     8581 aagtaattcc ttctggagct tcaacttcgt ctggatgaga tttaccaaca gccaaaacaa
     8641 gtttagatcc ttgaagctgt gcacggtaac caaccccacg catttcaagt tctttcttga
     8701 atccttctga tacaccaaca accatgttgt tcaaaagggc acgagtagtt ccgtggatag
     8761 ttttcatttc ttttgaatcg tttggacggt gaagagttat ttcagtacct tccacacgga
     8821 tttcaatatc ttttgagaac tcacgagtaa gttctccttt aggtcctttt acagttacaa
     8881 cgttgtcatt gttagcgagt tcaacaccag caggcaacac gataacttta ttaccaatac
     8941 gtgacatgtt tattttctcc tgttaaattg tcaggccaga acggccagtt ttcacggggt
     9001 tcagatactt atttagttca agagctgaac tgaacacgct ctaagaactg tgcaaaatag
     9061 ataagttggc ttgtttgtaa acaaacttct ccaacttcct aattttgctt tgttctttac
     9121 gagctttgta tcttgatttt accaaacgta agcgataacc tcaccaccaa cattcttttg
     9181 gcgtgcttct ttatcagtaa gcaaaccttc agaagttgaa aggatggcaa ttccaagtcc
     9241 gttaagaact tttggaaggt cttcacgttt tttgtagaca cgaagtcctg gtttagaaac
     9301 acgtttcaag ttagtgataa ctttctcacc atttggtccg tatttaagaa atacacggat
     9361 gacgccttgt ttgtcatctt caatgatttc aacgtttttt acaaaacctt cgcgtttaag
     9421 gatttcagca atcccttttt tgatgtttga tgcaggtact tcaagtactt cgtgtttagc
     9481 ttggttagca ttacgaatac gagttaggaa gtctgcgatt gggtcagtca taaccatttt
     9541 gtttttctcc tcttactagt agtttgcaag ttgcacttgc tagttaatac atgatacaaa
     9601 gagcgtaaca gtacgagcaa aaatagacaa tttaatgcag aagcaatgct ccaaagcaaa
     9661 ttggtctttt ttgccaaagc tgtagctcgt gttcaaattg gcaagcccaa ttgaacccgg
     9721 gctaaactct gtgtgaaaaa gataaacttt cctagaaact ttagtttctt cgtcaagttt
     9781 cctattttta cttggagttt tgacgctctt gatatcttaa attaccaaga tgcttttgtt
     9841 acaccaggaa tttgaccttt atgcgcaagt tcgcgaaaag cgatacgact cagaccaaat
     9901 ttgcggtaaa ctgaatgtgg gcgccccgta actctacaac gattatgtaa acgagtcggt
     9961 gaggcgttgc gaggtaattt agataaacct tcgtagtccc ctgccgcctt taatgcagca
    10021 cgtttttcag cataacggtc aacaattttt tggcgtttag cctctctagc taccattgat
    10081 tttttagcca ttagatttac ctcctatatt attttgcaaa aggcattcca aggcctgtaa
    10141 gcaatgcacg tgactcttcg tcagtgttag cagttgttac gataacgatg tcaagaccac
    10201 gagttttgtc aacgtcatcg aagttgattt ctgggaagat taattgttct ttcacaccaa
    10261 gtgtgtagtt cccgcgtcca tcaaatgatt ttgttggaac accgtggaag tcacgtacac
    10321 gtggaagtga aactgatacc aatttatcca agaattcgta catacgttca ccacgaaggg
    10381 taacttttgc accgatcgca acaccttcac gaagacggaa gccggcgatt gattttttag
    10441 ctttagtgat aagtggtttt tgacctgaga taagtgccaa ttcttcagca gctttttcaa
    10501 ggcttttagc gtttgataca gcttcaccaa cacccatgtt caaaacaatc ttatctactt
    10561 taggcacagc catcactgat gagtagttga attgttctgt caaagcagga actacttcat
    10621 taagatattt ttcttttaaa cgatttgcca ttatacttct cctttccttc gtgattaatc
    10681 aagcacttcg cctgattttt tgttgtagcg aactttttta ccgtctacaa atttgtaacc
    10741 aacacgacca gctacaccat ttttgtccaa aacttgaaca tttgatacgt ggatagctgc
    10801 ttctttctcg atgataccac cttgaggaag ctcgttagtt ggacgttggt gtttcttaac
    10861 aatgttaaca ccttcaacga taactttgtt tacttttgga agggcagtaa ggacaacagc
    10921 ttctgttccc ttatctttac cagcgattac gcgaactttg tcgccttttt ttacaaacat
    10981 taggtttctc cttgattttt cttacgccca taagggcacc ctagcttgaa gctaggggac
    11041 tagtttgttc ctaaaaatta aagtacttct ggagcaagtg acacgatctt catgaagcca
    11101 ccttcacgca attcacgtgc aactgggcca aagatacgtg ttccgcgagg agttttgtct
    11161 tcacggatga taactgctgc gttttcgtca aatttgatgt atgaaccatc agcacgacga
    11221 gcacctgatt tagtacgaac gataactgct ttaacaacgt cacctttttt aaccgcacca
    11281 ccaggagtag cttgttttac agatgccacg ataacatcac cgatgtttgc aaatttacgt
    11341 cctgaaccac caagaacttt gatagtcaag atttcgcgag caccgctgtt gtctgcgact
    11401 ttcaaacgag tttctgtttg aatcatttca gttttctcct ttcaggtttg attagatgat
    11461 gaccgcttct tcaacaactt ctacaagacg gaaacgtttt gtagctgaaa gcgggcgagt
    11521 ttccatgata cgtacgatat cgccttcttt ggcaacattg ttttcatcat gagctttgta
    11581 ttttttagag tagttaatac gtttaccata gactgggtgg ttacgttttg tttcaactac
    11641 aactgtgatt gtcttgtcca ttttgtcaga tacaacacgt ccaacaagaa ctttacgatt
    11701 attgcgttcc attgaaattt ctccttccct agtctattat ttcgcttcag attgaactgt
    11761 tttgatacga gcgatttgtt ttttaacttc tttcaagcga gctgtttgtt ccaattgacc
    11821 agtagcagct tggaaacgaa gttcaaacaa ttcttttttc aattcgtttt cgcgcttcgc
    11881 gagttcttct tgagaaagac cacgaagttc tttaacaaat tcttttactt cattaagttt
    11941 catgccttct ccttattctg cttcacgttt tacgaattta catttaactg gcaatttgtg
    12001 gctagcaagt cgaagcgctt cacgtgcaat ctcttcagat acaccagcga tttcgaacat
    12061 cactttacca cgtttaactg gtgctaccca accttcaggt gcccctttac cagatcccat
    12121 acgcacaccg atagctttag cagtgtatga tttgtgtggg aagattttaa tccaaacttt
    12181 accaccacgt ttcatgtaac gagtcatggc gatacgagca gcttcgattt ggcggttagt
    12241 gatccagtgg ctagttgtag cttgaagacc gtattcaccg aatgctactt cttttccacc
    12301 ttttgcttca ccgcgcattt ttccacggaa ctcacgacgg tgtttaacac gtttaggtac
    12361 taacattggt tatttacctc ctttagtgtt tttacgagct ggaagaactt caccacggta
    12421 gatccatact ttaacaccaa gtttaccgta tgtagtatct gcttcttccc aagcgtaatc
    12481 gatatctgca cgaagtgtgt gaagcggaac agttccttca gagtatcctt cagcacgggc
    12541 gatatctgca ccgttcaaac gacctgatac ttgagttttg attcctttag ctccagcacg
    12601 cattgcacgt tggattgctt gtttttgtgc acgacggaaa gcaacacgtt gctccaattg
    12661 acgagcaatt ccttcaccta caaggtgagc atccaaatca ggttgtttga tttcgatgat
    12721 gttgatgtgt acttgttttc cagtcaattt gttaagtttt gcacggagtg catcaacgtt
    12781 agcaccacct ttaccgataa ccatacctgg tttagcagtg tgaagtgaaa cgttaacttt
    12841 gtttactgcg cgttcgattt caatagttga aactgctgcg tcagcaagtt ctttttgaac
    12901 gaatttacgg attgcaagat cttcatgaag gtaatccgcg tattcttttt cagcatacca
    12961 tttggcatcc caatcacgga tgatgccgac acgcatacca attggatgta ctttttgacc
    13021 cacgatttta cctccttatt tttctgcaac agctacagtg atgtgagctg tacgtttgtt
    13081 gattggtgaa gctgaacctt tcgcacgtgg acggaaacgt ttcatagttg gtccttcgtt
    13141 tgcgaatgct tcagatacta ccaagttagc tttatccaaa ccaaagttgt tttcagcgtt
    13201 agctacagct gagttcaaaa ctttcaagat gatttcagca gctttgtttg gagtgaatgt
    13261 caagattgcg attgcatcgg ctacgctttt accacggatg ttatcaagaa caagacgtga
    13321 tttacgaggt gaaacacgta ctgtacgagc cattgcttta gctgaagtaa tttctgccat
    13381 ttatgttctc cttattttct acgtgttttc ttgtcgtctg cagcgtgacc tttgtaagta
    13441 cgagttggtg caaattcacc aagtttgtgg cctaccatgt cttcttggat gtaaacaggt
    13501 acgtgtttac gtccgtcata aactgcaata gtgtaaccaa tgaaacttgg gaagatcgtt
    13561 gaacgacgtg accaagtttt aataactttt ttcttttcgt cgttagcttg agcttcaact
    13621 tttttcatca aatgctcatc gacgaaaggt ccttttttaa gactgcgtcc catttttata
    13681 ttttctcctt taaatgttgt accacagcgg cttgcactcc tatggagcgc taccgagctg
    13741 gcggatttac tagttgctta agcgactagt ttaatattat ttctcgttgc gacgacgaac
    13801 gataagtttg tcagatttcg ctttcttgtt acgagtttta agaccaagag caggtttgcc
    13861 ccatggagta gatggtgctt tacgaccaac tggtgcttta ccttcaccac caccgtgtgg
    13921 gtgatcgtta gggttcatta cagaaccacg aactgttggg cggatacctt tccaacggct
    13981 acgtcctgct ttaccaaggt ttacaagtcc atgttgttcg tttccgacaa caccaactgt
    14041 agcacggcaa gttccaagaa tcatacgaac ttcacctgat tgaagacgaa caagaacgta
    14101 tttaccttca gaacccaata cttgagcaga tgcaccagca gcacgtacca attcaccacc
    14161 acgacctggt ttcaactcga tgttgtgaat caaagtacca actgggatgt tagcaagtgg
    14221 aagagcgttt ccgactttga tatctgcttc tggacctgaa acgatacgtt gacctacttc
    14281 aagacctttt ggagcgatga tgtatgcttt cacaccatca gtgtagtgta caagagcgat
    14341 gtttgcagaa cggtttggat cgtactcgat tgttttaaca actgcttcaa cgttgtcttt
    14401 attacgtttg aagtcaacca aacggtagaa acgtttgtgt ccaccacctt ggtgacgaac
    14461 tgtgatacga ccgttgttgt tacgaccagc cttgctcttc aatgcaacaa gcaatgattt
    14521 ttcaggagtg cttgttgtga tttcagcgaa atccaaagaa gtcatattac ggcgaccgtt
    14581 tgttgttggt ttataaacac gaattcccac gatatttcct ccttagatta ttcagcttca
    14641 gcagcaaaca actcgattgc tttagaatca gctgtaagtg tgatgatagc ttttttagtt
    14701 ttgttagtaa aaccagtgta acgtccaaca cgtttagctt ttggttttac gttgattgtg
    14761 ttaacattgg caactttaac accttcgaaa gcagcttcaa cagcttgctt gatcaaaagt
    14821 ttgtgtgcac gagtgtcaac ttcaaataca tatttccctg cttcaagttg agccattgag
    14881 ctttcagtga tgacaggttt tttgataaca tcatacaaat tcattatgca agaacctcct
    14941 cgattttaga gatagctgct tgtgtgacaa gaagtttgtc gctatttgcg atgtcaagaa
    15001 cacttgcagt tgtagcagtt gcaactttca cgtttggaag gttacgagct gaaagagctg
    15061 cgaattcatt tccttcttca aggataacaa gaactttaga atcgatgctc aatgctgcaa
    15121 gaacttttgc aaattcagca gtttttggag ctgtaaatga aagagcgtct acagctacga
    15181 atttgttttc agcaactttt tcagagtaaa ctgatttaag agctaggcga cgaacttttt
    15241 gtggaagttt gtagccgtat gaacgtggag ttggtccgaa gacaacacca ccaccacgcc
    15301 attgtggtga gcggatagaa ccttgacgag cacgtccagt tcctttttga cgccatggtt
    15361 tgcgtccacc acctgatact gcagagcggt ttttaacagc gtgtgttcct tgacgaaggc
    15421 ttgcgcgttg gctgatgatt acatcaaaca caactgattc atttggttcg ataccaaata
    15481 ctgcatcgct aagaacaact tggccagctt ctttaccagt ttggtcaaat aatgttacgt
    15541 ttgccattgt gactgatttc ccctttcttt attatttacc agctttaact gctgatttga
    15601 tagtgataag agatttctta gcacctggta cgttaccttt gataaggata acgttctttt
    15661 ctggaacaac ttgtacaact tcaaggtttt gaattgttac gcggtcgcca cccatacgtc
    15721 ctgcaaggtt tttacctttg aatacgcggt taggtgcaac aggtcccata gaacctggac
    15781 gacggtggta acgagaaccg tgagccattg gtccacgtga ttgtccgtgg cgtttgataa
    15841 caccttggaa acctttacct ttagaagtac cagttacgtc aacaacgtcc ccagctgcga
    15901 atgtttcaac tgtaatttca gcaccaactt ccaagccttc aacgtttttg aattcacgaa
    15961 tgaagcgctt aggagccgtg ttagctttcg ctacatgtcc tttagcaggt ttgttgctca
    16021 atacttcgcg tttgtcatcg aaaccaactt ggatagcgtt gtatccgtct gtttcaacag
    16081 ttttaacttg aagaacaacg tttggagttg cttcaataac tgttacaggg atcaattcgc
    16141 cagcttcagt gaagatttga gtcattccca cttttttccc taagattcct tttgtcatga
    16201 gaaaatagtt ccttttctat atttttattc aaaaagtttt taacgagcgt tttttatgct
    16261 caagtctaag atacaaaggg cgtcaaactc aacgtgaaaa taggaaactg acacagtgtc
    16321 tagcagacgc gaggaagttt atctttttca caccaagttt agcccgtgtt caattagatt
    16381 gaaacaccag cctctgctct cttatatttt agattaaagt ttgatttcta cgtttacacc
    16441 acttggaaga tccaatttca tcaaggcatc aactgttttt tgagttgggt taacgatatc
    16501 gatcaaacgt ttgtgtgtac gcatttcaaa ttgttcgcga gagtctttgt atttgtgagt
    16561 cgcacgaatg attgtgtaga ggctacgttc agttggaagt gggattggac ccgcaacttg
    16621 tgcacctgta cgagtagctg attctacgat ttttgcagcc gctgtgtcaa gcgtacggtg
    16681 ttcgtaagct ttcaaacgga tacggatttt tttgtttgcc atctttttct ccttttcgtc
    16741 tatttaagat aataggctag ctccacaaga aaaccgacgc ggtgttgcgt ggcaatgcaa
    16801 ccgagcgtgt cgcaacctct tgcatcaaaa ctaaggctgt aatttacagc accataatag
    16861 aataacacaa atcccctgcg attgcaaggg atttgttagg ttttttcgtt tttttgggat
    16921 gaaactgttt tcctactttt tctttctaaa attagggatt ttcttctata tttcttctat
    16981 acataagtta agtcctcttg acatcaaatt tatcttctga ttggtccact aagatatccg
    17041 ccttagactc agtttcttta tagtatcgca gatactgctc ccgtctcatc tgatggctag
    17101 ccaatataaa ggatgcatcg cgatttctca cagtcgtatc tctagcaagg cgtcgcttta
    17161 attcggtctc ctcatccgtg tagaaacaga tggttttttc aaagagttcc ttgggtagaa
    17221 agccaacaga catcccttcg acaatcaaaa ttggtttggc tccagacaag acctcactag
    17281 ccttccaagg ttcttcaatt gtcaagacat ccatacccgc ctgcaaggca aggatatctc
    17341 tctgcaaact ctccagttca tgcgccactg gcagactggc tgtcaccttt tgattcggcg
    17401 cgtccttggg tactaccaaa tagcgtccgg aggtgatata gggatctgtt tctagcaaat
    17461 ttactgtagt agaatctaaa gcttggtaca attcctgtgc aaaggttgat ttacctgaag
    17521 ctccatgacc gtatattccc agtgtcctga ctttccccgt ctcgatctct gagactagtt
    17581 ggtctactaa gtcttttttc ttcattctct cttcacctgt tcatagcttt cttttccgtc
    17641 attgagcttg tcccaaatca ctacttgccc acttttgagc gatttttgca catcgataat
    17701 tcgttggttg gacgaacctc gaaactggag catgagattt ctcttagttc gatcgtatcg
    17761 tccatcgaca agaatgtcaa tcaatgataa gagttccagt ttatctggag tttccaacat
    17821 catttcttcc caagtgtagc ccgtccagga ccaaatgtcc ttgtctggca attcctttcg
    17881 gatgcgttta actagaggca agagaatgcc agtattgaga aaaggctccc ctcccagcaa
    17941 agtcaagcct tgaacatagg gttgggcaag gtctgccata atctgctctt ctaattctgc
    18001 tgtataggga atgccagcat taaaagacca agtcgcaaca ttataacatc cctcgcagtg
    18061 aaacatacag cctgatacat agagagagtt gcgcacgcct tcgccgtcca caaagttaaa
    18121 ggccttgtag tcaatgatac gaccttgact aagttcctcg cttttccatt cttgtggttt
    18181 tggattattc attcgctacc tctatccaat aacgctcgac tccattgcga gcatcctcaa
    18241 atattccacc atttgctaga atgactgctc tgctagcagg attattcacg ctacaggtca
    18301 ccagagcttt cttgatgttc ttttccttag caacttgcaa gccctgacgg agagtctctt
    18361 ttgcataacc cttgcctctt tcagatggac gaatggagta gccaatgtgg ccaccttctt
    18421 ctagtagaaa gttactgagg cgcaaccgga gattaagaaa tccaactgct tgacctttct
    18481 cagaaaaaac cactaactga attgcaggaa cccatccttc aggcagatta atccccattt
    18541 cctgttcctg attgctttct aaccagtctt catacacaaa gttctctgta ttccagaaac
    18601 cgccgtcgtg aggcgactga aatttttcaa actctgtcat catctctaaa actgtttctt
    18661 tatctgctaa tcttggtctg cgtaattcca tccctacctc ccactatgag aaaagcgaga
    18721 gctggctctc acttttattt tttcttgttc ttgtttaaaa attgttctct gaagctaagc
    18781 aagcgttctt tcttaccagc tccaccttta gagtgtttct cgtgataacg ggtcacttgt
    18841 gcgcgcccct tatcgtctag ttgatatttt cccatttcat ttctttctaa tttgttactt
    18901 gatgcccagc tattttaatc gttgaaccat tcatatgttt gacacgcgca gcgatttcct
    18961 tgtgacgccc gttaaccatt ggtctcgctt gaggattgcc aagatagcca caagtccgtt
    19021 taacaacgtc tactgtttta ggatcgctat tgccacagtt tggacaagca aaccctctct
    19081 cagttggttc aaaatcccct tcaaagtcac acttgtagca acggtcaatc ggagtattgg
    19141 tgcctagata gcctacacgg tcataagcat aatcccagac agcttccaag gcctttggat
    19201 tttgctgaag gactggatac tcacaataat ggatgaaacc acctgacgca cctgcttctg
    19261 gatagacttt ctcaaagtcc aatttttcaa acggtgttgg atttttacga acatcgtagt
    19321 ggaaagagtt ggtgtagtat tccttgtctg tgatatcagg aatagagcca aacttgtcta
    19381 tatctagtcg gcagaaacgg tctgtcagac tttcggatgg tgttgagtag atagagaaat
    19441 ggtagccata ttggtctgac cactcttcta cacggcgttt catatcgtga atgatgtcta
    19501 gcgtgaattc cttagcatct ggattacttt cccagctgtt accaaagaaa actgtcgcta
    19561 cttcatacaa gccgatatag cccagcgaaa cggtcgcacg acgattctta aagagctggt
    19621 caacactttc ttctttacct agacgatggc caaaagcacc gtactgataa agaataggag
    19681 cattcgctgg tgtcgcctct ttagtgcgtt cgacacggta aacaagagca tcttctgcga
    19741 tattcattcg ctcgttgaag atttcccaga acttattcat atcaccttca gactcaagag
    19801 caatacgagg cagattaacc gtcacaacac ccagattcat gcgacctgaa ttgacttcta
    19861 caccattttc atccttccac ccttgaagga aagaacggca gcccataggc accttgaaag
    19921 aacctgtcaa atcaacaatc ttatcataag acaagacgtc tggatacatc cgcttggttg
    19981 cacactctag agccaactgc ttgatgtcat agttgggagt tccttcctct aagttgaggc
    20041 ctcttttaag cgtaaagata agtttaggaa agatagccgt acggtgttct gaaccaagac
    20101 ccttgatgcg aatgtttaaa atagcttttt gaatttctcg ttcaaaacga ctggttccca
    20161 gaccaaaacc taacgaagta aaaggtgttt gtccatttga agtgaagaga gtattgattt
    20221 catactcaag agattgcatg gcatcgtaga tgtccttttg cgctttcttc caagcgtaat
    20281 cttcctgttt ttcaggcaat acccactctt ctgcatcttt gagatgtttt tgataattct
    20341 tctctgcata aggcgccaaa atttcatcga tacggtcagc tgaacagcca ccgtactggc
    20401 tagaagcaac gttggcaatg atttgagaaa tctgtgctgt cgcagtctgg atagacttgg
    20461 gactctctac ctctgcattt ccaatcttaa aaccattttc caacataccc ttaaaatcaa
    20521 tcaaacagca gttggtcata ggggtatagg gactgtagtc caaatcgtga tagtggatat
    20581 cccccttttg gtgggcattg gctacgtgct taggaagcat ttgcagtccg attgatttcc
    20641 caacaatccc tgctgtcaaa tcacgctgag tgttaaagac atcactgtct ttattagcgt
    20701 tttcattgac aactgtctgg tctttgttga gaagtttatg aatactaaag ttgatatccg
    20761 tcgcttttga gcgctcaaaa tccctctgtg tccgataagt aatatactcc tcagccagcg
    20821 catattcttt ggcttcaagg agttcatgtt ctacgatatt ttgaatttcg taaatcttaa
    20881 ttccctgtgg aaagcgacta tgaatttctg taataattcg ctcagtcaga tcattgaggc
    20941 gtttttcaac caggggtgtc acatccataa ccttgtcagc cgccttgtgg agagccttgt
    21001 caatcttgtc cacatcaaat acaacacgtc tcccatctcg tttctcgacg aagagagttg
    21061 gcaaaattgt aattttttct tctagtgcaa tcatatgcat gctcttttct aaaatgttct
    21121 ttctaaaaag tattatacca ctctaaaaag aaaaatcaat atcttgtgtt aaaaatccta
    21181 aaatttttaa aaatacacaa gatattgatt tggttattta attttataga ctttaaactc
    21241 tgagtaatca gtctttactt gttggtaatt ttcttttaag agtgtttcca cttcagacca
    21301 gactaccacc ttatcattta ccacaatcac cttaggttgt ttttctttca agtcattaag
    21361 taacttatta cgattttcct cagttgctgt atagtgcaac ggggacaaaa tcgccgatgg
    21421 cgacaagcgc tcactcttac gataaagagt cgcagtatca tcccatgcat agatagcatc
    21481 ttccgtattt gtctcctctt ttaccaaatc agcaagacga ttacgttctt gataaggtac
    21541 tggataaagg acaaacttca tcaaaaaagg aacagacaaa agatagacaa acccaaaaac
    21601 tagcagatat agatttcctt tgaagaaacg actccatagg ctaactggcg tttctcttcg
    21661 gcttcttcta gcactacgcc ccctctgttg actcttaata ttggttacca ataaaagtag
    21721 gaaaacaggg aagacgacca tcaaataaga agcgtgcaga ggctcttgtg aaaagaaaag
    21781 taaaatcaaa cctaaaatta ccacaagact tgcaggaacc gaaatgacgt atagtttaaa
    21841 gggtttggat tgaaagagac ctaaaaagat acaaaccaca aatcccaaac caagggacaa
    21901 caagccataa aaaaacatat tctctaaaat tttagaagta aaatcaaagc gaatactgtc
    21961 aataggataa cgaataccac taatcgcatc cccaaaactt cctgttgcag cactatagta
    22021 ggcagttgga taaaagacaa gtgaaaaacc taaagccact gcaagaaact gataaaaccc
    22081 atgcgcaaag cgtctatgcc caaggttaaa gaccaacaag cctaaactca ctacagcaat
    22141 aaacaggagc gatgataagg gagcaaagaa aaatccgcct gccaaagcta gcccaatccg
    22201 tacaaatccc ttatcatggc ttggattgct taggtaagcc gcaactaaac taaaggctgc
    22261 gaataagaaa ggaagcgcta aaagagtcgc atagcctcca ccaaaagcaa gacctgtaac
    22321 tagcatgtaa aaaatagtca ccagatgtcc agcttggtct ccttgctctg tcaaggtgtc
    22381 cgctgatcta aaaaggaaaa atccgcctgc taccaaggct aaccactcaa agatggcaaa
    22441 gaaaaatccg ccctgactca cgtaagtcag caaataataa agcaaacctt gacttccata
    22501 atagtcgctg taaatcttcc ctgtctgatg aagcgcccaa cctgcataaa aatcctgcac
    22561 ttcttgtgca ctcattaagt cgagtaatag cggtactcct agagttatcc ccgttacaag
    22621 cgtactccat agtaaaattt tcactaaagg aagacgactt gattcacgat gatgcgattc
    22681 ttgttcgatt tggtattcta gaggttcacg attctcctta tgaacttctt ctactctacc
    22741 atacacactc atatcgtttc tcctgttcaa tttatctgtc ttagtatatc aaaaagtcct
    22801 aggattgtca gcttgcgatg gctgtttgag tgattttttg catagtttca caaaggtttc
    22861 aatttcccga aagcggtgta aatgtgtctg tttgaactca atcatatcat tcacttcttc
    22921 cttagttagc atgaattccc ctcctctttc tttctattcg taaaagacaa gaaaaatagg
    22981 tctggtttgt atcctaagtt ctagatttct tataagatag gggcgaatag ctgggcgatt
    23041 tcttttacaa gcttttgata ccagctcgtt ttgatagaat gaggatagac ttcctgagaa
    23101 tctgcaaata tatttcgaaa atctcgggcg atttccctta tagaaggagt tttatagagt
    23161 aagactgcat tttcataatg gtgtaccaag ctccggtagt cgagattgat tgtccccacc
    23221 accgcaaaat cttcgtctac caacatctgc ttactatgaa taaaacctgg actatactca
    23281 taaatccgaa caccagcaga aagaaggtcg ggataagctc ctctcgtgac taactgaatg
    23341 aacttcttat ctggtatgta aggggtgata attcgaacat cgacccctct catagctgca
    23401 tttttgattg tctctgttaa atcataatct ataatcaaat aaggtgtcgt aatatagacc
    23461 gattccgttg cttgattgat taaactctga taaacttttt tccctacctg cgctcgaaaa
    23521 attggcttgg gtccacttcc gtatggaatg gttaaaccgt cactcgggat agaatgattt
    23581 tctaaatgat attgatcaaa atcactaatt tctcctcgat taatgtacca agtggtcaaa
    23641 aataagcgtg tcagggcttt tactgctagt ccgtctaagc gaattccact atccttccaa
    23701 taaccaaatc tctcgacgtg gttaatgtac tcatctgcca gattgacccc accagtatag
    23761 gctatctgac catcaacaat caatattttt ctatgatctc tgttattata agccactgtc
    23821 aaacgaggaa taactttatt gaatttatgg gcctcgatgc ccagctgacg aagtcgatgt
    23881 gcataatctc ctgttaaagt agccatacag ccgatatcat catagagcat cttaacctct
    23941 acaccctgag ctaccttttg ctctagtata tctagtatgc gattccacat caaaccttct
    24001 tctataatgt aatattccaa gaaaataaat ttctcagcct ttttaagatc ttctaccatc
    24061 tttttccaca tagcttctcc gttaggaaaa aatgtagagg cagtttgatc atagatgtca
    24121 gcattggtat ccatactcaa taaggacttg atgactccat aagctgcctt gtcactttct
    24181 tttaatttct cttttagtag ctggctattt gcttcttgga aatgcataga gcctagcttc
    24241 ttcagttgtt tgatttcttt tttggacaat cgcctttcac caaacatcag atagagcaag
    24301 ggaccaaata ctggcacaaa ggctactaac aaccaggtta ccttattctc aggagtcgta
    24361 ttacggttga ctatcgaaat gattgtgatg atactcagta gaatgaggac agtaatccat
    24421 aaaatgggag ccatgcgtcc taaataaaga aagagaccaa aaacaagaca aagttcaagt
    24481 agcataatcg aaagactaaa gccatacttg gacatcaata attgaaattt cctatatttc
    24541 atatcccctc cttgatagtt tgaatgctaa aaacaagtaa ttgatactag tataacgcag
    24601 gtattcggta gaaggcaagt atttatgatt attttctagg taaaagtaaa aaggctgaaa
    24661 aatccagccc tttctacttg catagtctta tttagttaaa acgatttggt ccgatgggtc
    24721 tctatccata tcatctacga cgatttgatt accgtttaca gtgtaaattt tgacatcatc
    24781 gccaataatc atgcgttgat ttgctgaatc aaatgtaacc tgtttgactt tctgatcccc
    24841 gtcagattcg agctcagtcc atgtaccagt cgttccagtt accactaaag tgatacggtc
    24901 tccgtcatcc tgaccagtat aagtcccatc aatatcggtc ggttgagcaa caggttggtt
    24961 ttgtactgga gccgcttgat tttggttacc tcctgcattt gcagtattgg tattctgttg
    25021 agcaggctgt tggacctgct gagcaacagg ctgttgaacc tgttgagctc tttgtgaaca
    25081 agctactaag agactaaaac ttgctagaga agcaagagaa agtgtgaatc tttttaattt
    25141 catgatgaat ttcctttctg ctaccaattt agagaaattt tctctaacca gcaattcccc
    25201 tagtataaca agttcaaaaa agggggtcaa tttatctgct cacggtccag caggtagccc
    25261 cgtacttctg agataaaata gagagaccct gtaacgaaca gcaagtcttg agcgtctgcc
    25321 ctttcttcga aactgctgat aaattctcgg taagagggaa ttacatggta acctgttaca
    25381 tctgtctcgt ccaaagaccc ttgatagtca aagccggtca ttttgagttc cacttgaggt
    25441 aaattttcag tcagataacc caacatccct tgataatcct tacgtttcaa ggatccaaag
    25501 aggatttgag gtcgatagcc ttcctgctct ttttctttga taaactcaac caagcgagtc
    25561 aaggcaggga ggttatgagc accatccaag taaatctgtg ggcgaatacg ctccaagcga
    25621 ccagcccaat gggtttgttc caaggtcttt cttacagcct gttcatcaat agcttccttt
    25681 ctttctccca taaaaagaag aaaagtttgc aacgccaagg ccgcattctc ctgctgatag
    25741 gctccttcta agcctatgtt cagctgtgaa agatttagta aagagcttga aaaatcacca
    25801 ttcagcactg aaaaatcttg acctgcctga taaaggtcaa cagctaaaga ttcggctttt
    25861 ttctgacaga taagcctagc ttctggaggc aatttcgcaa tcactgcctt cttaccagcc
    25921 ttgaaaatac cagctttctg ctctgcaatt gcttctagac tatcacccaa ggtttcttga
    25981 tggtcaagcc caatggaggt gatgacagca agctctccag ttaccacatt ggtcgtgtca
    26041 agtaagccac caattcccac ttctaataaa accaaatcca cctcttgctc cctaaaataa
    26101 agaaaagcaa ccaaggtcag caattcaaaa aaggacaact ggtcaggagt ttgcagaagc
    26161 gttttctcca tctccttgac ctgatcagcc aaacggataa agtctgcgtc tgctataggt
    26221 tgcccattaa tgcaaattcg gtcattgatg gatacgatat gaggggaggt aaaggtcgca
    26281 acttttttgc catgccccat aaataattcc ctcataaaag caatggtaga tcctttccca
    26341 ttagtccctg ttacgtggat aatagggtaa gactgctcag gatttcctaa caaatccacc
    26401 gcttgctgca ttcggcccaa acctgatcga aaatttaaac caatccgact atggagccat
    26461 tcttctactt caaacataca catctccttg acaaaagtcc aatcaattat cgcattaaag
    26521 tatggttact aataaaaaca aggccaggat tttcgtcccg acctcttacc tggttagcta
    26581 ataactagcc actatgaatg tgaatatggg ctaaaaacat ccactagatg ttccaactct
    26641 tctcaatttc taagagttgg ggtaaaaatg ttcactggac gttccaactc ttccccattt
    26701 ctgggagttg ggctgataca gtctcccaga ctgtatcact cctccataaa gctgttgaag
    26761 acttcttcaa tcatgttcca ttcgtcttct gagtcttctg ggattggttg caattcgcct
    26821 tctgttccat cttcgttttc gatgaatgag taagcttgga tttcaacttg tccgtcttcg
    26881 tcttcttctg cgttaactgg tactagaaga acatagtttt taccaaattc ttcttttcca
    26941 tcaattgtca aaaggatttc aaacaaggtt tcatttcctt gctcatctac tagtgtgatt
    27001 agttcacgtt cttcgtggtc gtggttatga tcgtgtgaca tagcctctcc tttatattaa
    27061 aattttctat ctaaataatt ttgtaaaatc agctgagctg ctaacttatc aatgactttc
    27121 ttgcgcttat tgcgactgat atctgcttgt tcaatcaaca tgcgctcagc agccactgtt
    27181 gtcaagcgtt catcctgata gtctactggt aaaccaaaaa actcttctag ctttgctccg
    27241 taggcttgac tagcttctac gcgcggtcca cttgtattgt tcatgttttt aggcaagccc
    27301 actacaaatc gttccacctt gtaagtatca accaattcct taacgcggtc aaaaccaaat
    27361 tggccttgtt cttcatttat ctggatgatt tcaagccctt gagctgtaaa accaagcgga
    27421 tcgctaatcg ccacccctac cgtttttgaa ccgacgtcca atcccataat tctcataggt
    27481 tatagatcga ctccttgtcc tttgaggtag tagcgaacca attcctcaac gatttcatca
    27541 cgctcatact tacggatttg atttcgtgca ttattataac gaggaacgta ggcagggtct
    27601 ccactcaata cgtaacctac gatttggtta attgggttgt aacccttatc gttcaacgaa
    27661 gcataaacat ctgtcaaagt ttcgctaatt tcttttttat tggaatcgtc caatttaaaa
    27721 cgtactgttt cttcagtaaa tcccattcta acaccctctt tccttagaat agtaccatta
    27781 tagcataatt ccttaccttc tacaattcag gcagtctatt tatttggatt ttctattgtt
    27841 ctgtcgcgcc atttgccaat ctatctgaaa tatatttgct tggttcattt ttcaaaagat
    27901 tttccaaacc aatattcttc agatgttcca actgggaagc cttcttgaca tccagaactt
    27961 gaaaatcaaa actagtcgtt gtttgaagtt ccgttgcgct caatagtttt gtttcaagtt
    28021 tgaaacctgc caatttacga gcttcaatga tagacttatc cttctcctcc gcttcaagaa
    28081 gagctttttg agtttcctcc actccatgtt ggtcaatata agtcttcaac tcatcagaga
    28141 ctggacgttt ttgttggata gttagactca aaaaagtctt gtctttataa gtaattgttt
    28201 gtgtctgctg gctaccatca tctgacttgg gcaagaccaa agtcttagtt acaactgtat
    28261 tcttctcagc attttcaata actggcaatg ccgactgaag cgtatctttt tctgtttttg
    28321 tagctggtcc agtttctttt ttctgtccgc aaccaaccag gacaaaaagg aaagctagac
    28381 taacaagaac tatttttttc atttctttct tctttctttt tgaaattaaa atagaataag
    28441 actgggaagt gctcccagcc ttgatgttta tagagctgca cgcaaacgtg cttctgcatt
    28501 ttctacatta cggacagagc gtggtaggaa ggcacgaata tcgtcttcct tgtagccaac
    28561 ttgcaggcgt ttttcatcta caaggattgg gctctttaaa attctcggtg tttccataat
    28621 cagattgaga acttcattga cactcaaatc ttcaatatcc actccaaggg ctttggcata
    28681 gcgattttta gatgaaacga tgctggctat tccgttatct gttttggtta gaatatccag
    28741 taattcttct ctcgtaattc cttctttacc aaggttttgt tctttataac ttaactggtg
    28801 ggcattgagc caggtttttg cttttttaca gctagtacaa cttgagactg tataaatttt
    28861 aatcatgtac ctaccccttt cgctacatgt tactatcagt ttagtctatt ataccataaa
    28921 aaacatccga cttgcgacct atttttaatt ttttttgact tttttcgtca ttttcgtact
    28981 tttttcttga caaacaacta aatgactatc aactcttttg gagctagggt caataattca
    29041 caacctgtct ctgtaatcag gatatcatcc tcgatacgaa cgccatattt gccttcgata
    29101 tagatacctg gttcatcggt caaggccata cctgtcttaa tagtttctgt agaagtctgg
    29161 ctaaagtagg gttcctcatg gatatccaga ccaataccgt ggccaatgcc gtgagtaaag
    29221 tagtcgccat aacctgcctc aatgataata tcacgaggga ttttgtcaaa gtcacggaaa
    29281 cctaagcctg ccttagcttg gtcaatcaag gcttggttag cttttagaac cgtattgtaa
    29341 atctctgcct gctcatcgct aacatgccct agatagatag tccgggtcat atcactgaca
    29401 tagtggtcat agagacagcc gaagtccatg gtaatggctt ctcccaactc cactggtttg
    29461 tgcattggat gggcatgggg tttagaagaa ttgataccgc tagctaggat cgtatcaaaa
    29521 gataagccag atgctcccaa ctcacgcatg cggaagtcaa ggaagttggc aatctcaatt
    29581 tcagtttttc ctggtttgat aaagtcaagc gcatcgcgga aagcttggtc tgagatagaa
    29641 caagccttgc gaatcgctgc aatctctgcc tcatccttaa tcatacgaag accttccaca
    29701 aactgagttt gtggaagcaa gttcaaacct gcaaaagctg cctgcatacg gtggtaataa
    29761 gacactgaaa tctcatcttc aaaaccgata cgagtcaagc ccatgtcctt aacaattcct
    29821 gcaatgacag ccaattcatc acgatcagcc acaatctcaa aaccactggt ttcttgctta
    29881 gctgcgatga tatagcgaga gtctgtcact aagacctgac ggtcacggct gataaagact
    29941 gttccgtttg agccccaaaa accagtcaaa taatagacgt ttttaagatt gttgatgatg
    30001 ataccatcta gttctttttc ttgcatttta gctagaaatg cttgtacgcg tttattcatg
    30061 atgtaacttt cctttcaaat agtgtcctgt atagctggct tcgttggcag ctacttcttc
    30121 tggagttcct gttacgatga tggttccacc accgacaccg ccctcaggtc ccaagtcaat
    30181 gatatggtct gccgtcttga taacatccag attgtgctcg atgacgagga ctgtattgcc
    30241 gtcgtctaca aagcgagcta aaaccttgag caggcgagca atgtcctctg tatgaagccc
    30301 tgtcgtcggc tcatccagaa tgtagaaaga ttttcctgtc gagcgtttgt ggagttcgct
    30361 agctaacttc atacgttggg cttctccccc agaaagggtg gtagctggct gtcccaaggt
    30421 cacatagcct agacctacat ccttgatggt ctggagtttg cgttgaattt tcggaatgtg
    30481 ttggaaaaat tctaccgcat cgttgaccgt catatccaag acctgcgaaa tattcttttc
    30541 cttgtagtga acttctaggg tttcactgtt atagcgggtt ccgtggcaaa cttcacaagc
    30601 cacataaaca tctggcaaga agtgcatctc aatcttgata atcccgtcac ctgagcaagc
    30661 ttcacagcga cctcccttga cgttgaaact gaagcgcccc ttcttgtagc ctcgaatctt
    30721 ggcttcattt gtctgagcaa aaaggtcacg tatatcgtca aaaactcctg tataggtagc
    30781 tgggttagac ctcggcgtcc gtccgatagg gctctggtca atatcaatca aacggtcgac
    30841 atgctcaatc cctgtaatag tcttaaactt accaggtttg tctgaattac ggttgagctt
    30901 ctgggcaatg gcttttttga gaatgctgtt gattagagtc gatttccctg aacccgacac
    30961 acctgtcact gcgataaatt ttcctagtgg aaagcgagcc gtgacatttt gcaagttgtt
    31021 ctcacgcgct cctatcactt caataaaacg accatttccg acacggcgct cttctggtac
    31081 tgggatgaca cgtttgcctg acaagtactg acctgtgata gacttgctgt tgcgagccac
    31141 ttgcttaggt gtacctgctg caacaatctc accaccaaaa acaccggcac caggaccaac
    31201 gtcaatcaga taatcagctt cacgcatggt atcttcgtcg tgttccacca cgataagagt
    31261 attgcccaag tcacgcatct ttttcagact ggcaatcagg cggtcattgt ccctctggtg
    31321 aagaccgatt gacggctcgt ctaggatata gaggacgcct gataggttgg aaccaatctg
    31381 ggttgccaaa cgaatgcgct gactttcccc acctgaaagg gttcctgctg aacgtgacag
    31441 ggttagatag ttaagaccca cattattaag gaaggtcaaa cgatccttga tttccttgag
    31501 aatgggacga gcaatgatgg cttcattttc agacaaagtt aactggctca ccaagtccaa
    31561 gtggtcagcg atagacaggt ctgagatttc tccaatatgt ggcccttgct ggccgcccac
    31621 acggacagac aaggcctggt cattgagacg atagccttga caggttccgc aggtcagctc
    31681 attcatgtag agacgcatct gagtgcgagt gtaatcgcta ttggtttcat ggtaacgacg
    31741 tttgatatta ttgataactc cctcaaacgg aatgtcgata tcgcgcacgc caccaaattc
    31801 attctcatag tggaaatgga attccttacc atctgaccca tagagaatca agttcttatc
    31861 ttcttctgac aggtcctcaa aaggcttatc catagccact ccaaagactt tcatggcctg
    31921 ctctaacatg tttggatagt agttggatga gataggattc caaggtgcca gcgctccctc
    31981 atgtaaggtt ttgctggcat ctggcactac caaatcagta tccacctcca gcttaatccc
    32041 caagccgtca cactcactac aagagccaaa gggagcattg aaagagaaga gacgaggttc
    32101 taactctggg acagtaaatc cacaaactgg acaggcataa tgctcagaga acaacaactc
    32161 agagtcgtcc atggtgtcga taatcacata accttctgcg atacgaaggg cagcttcaat
    32221 ggaatcaaag agacggctac gaatgccctc cttgataaca atacggtcaa ccacgacatc
    32281 gatattgtgt tgcttgctct tagacaactc tggcacttcg gtcacatcat agacttcccc
    32341 atccacacga acacgaacat acccgtcttt ctgaaccttc tcgataacac tcttatgttg
    32401 gccttttttc ttgcggatga caggagccaa gatctgcaag cgctggcgtt caggtaactc
    32461 caaaacctta tcaacgattt gctccacaga agaagcattg atagctccat gtccgttgat
    32521 acagtaaggc gtccccacac gtgcgtagag gagacgcaga tagtcattga tttcagtcgt
    32581 cgttcccacc gtcgagcgag gatttttact agtcgttttc tggtcgatgg aaatagctgg
    32641 gctgagacca tcaatggcat ctacatctgg tttttccata tttcccaaga actgacgagc
    32701 gtaggcagac aaactctcta catagcgacg ttgtccctcc gcatagagag tatcaaaagc
    32761 cagactggac ttccctgaac ctgacaagcc agtcacgaca accaacttgt ctcgcggaat
    32821 ctccacatca atatttttta aattatgggc acgcgcccca tgaatgacaa ttttatcttg
    32881 catctttgtt ctttctagtc cattattgct taccattata ccaaaaaaag tgagattcta
    32941 ttacccaaaa ggccgatttt gtagtataat caacaatcgc ttattttatg tttccttagg
    33001 gcttcctaac ccttatatca cgcgcttttt aataaaaatt actaacatta ctttttacta
    33061 cttgctcccc caaagtacgc aaaaagggga gcaaaaaagc cccacaaaag ggctaagatt
    33121 tgacgagttc agcaggcaag aaactagcac ggtcaaacgt gcttttttat tgctggttgc
    33181 tgatagatat attataccat gaagcgcgtg gtttataaga ttatgacctc acaaaagccc
    33241 ccagattcgt ttctgagggt ttgtagttta tccatggtgt tttagttgtc cagtacgaaa
    33301 caaagcgaaa tacgggcgaa tatgtggctt aggactcccc catactctcc taattccgtg
    33361 gtaaggttaa atcaatcccc gtttacaata cctgttaagt gttctatagc tttttgcctt
    33421 ataatgtata ctgtagtatt tgatctatct atttcttcag ccacctccga aactacaaga
    33481 tcattcaagt aaaaaagtct tagaacagaa cgctcaagcg gattggccag tttatcgatt
    33541 agctcagata ttttcattct ctcttcagta agtcgctcaa ttctctgtaa agtgtcctct
    33601 tttagcttca gaacacttat aagattgttc tctgtcttat tctctctact tgtctgcacc
    33661 ctgctatggc ttagtgttgg ttttttgata atgccacctt ccagggtttc caattccaaa
    33721 tataagcctt tgatctcctt gtttatccac ttaacgccct ctagtttttc ttttacttgc
    33781 tctggtgtca tgcctcggcc tcctttgtga tataatagtt ttatggaata attcataaag
    33841 gagtcagccc tgtgctggct ttttttcatt ttctctagct tcgctctagg ttcaagtcca
    33901 ttctccatac catttgataa gcaattaagg gatgttttta tctctcttat ttccttgtca
    33961 ttctgcaagc aattaaggca agttatttct ttgcttatct gcttatcatt ttgtaagcaa
    34021 caaatccaaa ataacagact tttaaactgc tcttatctcc ttatcatttg gtaggaaaat
    34081 aaggggagtt attttagttc ttatttccct gtcattttgt aaggagaaaa ttcaaattaa
    34141 ggaagctaat aagtctcctt atctccttac agtttttcag ggagcaaaat caaaataagc
    34201 gatgttattt cctgtcttat ttccttcccg tttgacaagg agaaaaacga aaataagggg
    34261 cttttaaatt cgtcttaact ccctatcgtt ttgtaagcag ttaagaaggc ttattgtcgt
    34321 ccttatctgc ttgtcattct gcaaggagta gatccgaaat aagagggcta aaaacttctc
    34381 ttatctgctt gtcgtttctc agggggttaa ggagggtttt tattgctctt atctacttga
    34441 taaatgatag gggggatata gccactttct cggcgttcgc tcggagttca acacacataa
    34501 ccctgccatt tgtcaggcat atttactgcc actacctaag caaaatctca ccttttctaa
    34561 ccctcggtaa acctctctac ctttgtaaaa ccttagtatt tttaagtatg taaccttgta
    34621 ctaaccttgt actttttata tatgctacct taccaaaacc ttaccattgg aaaacttcga
    34681 taccttaccg taaccttacc gttctatggt tctaaaaaag tagctatacc ttgtggtaac
    34741 cttggggttc tatcactaga aaaaagccct gtaccttgct aaaaccttgc tattttgaag
    34801 tatgtgacct tagcctaatc ttagcctttt ttaaatattc aacctcaccc ttacctcacc
    34861 cttttttgga acgcttactg cacccttttt ttggaacgct atacttaatt aaatccttga
    34921 tatatctagc ttttttaaca ttcaaaccgt ctaatatgta gtatttgttt gttttgtaaa
    34981 ttgcacacta ctacaaatta ccttagagaa ctcaaaccat tcagccaaaa gctatcccct
    35041 tttctggtgt agttaataaa cttttgataa tgcttgtaat atcgtttctg tttcatgtat
    35101 tttggtcttt caggaaaact atcaaacata tatccgccac gtctaggact ccaccctggt
    35161 tctacctttc tagcttcttt tagtgcaagc tcccagtagt attggcaatc cgttttactg
    35221 cggttcaggg tgtgcttgtg gatatctaga caagtaccgc aactaaaata caaataccgt
    35281 ttataaagca acctgcaccg tctaccacaa tcagggcaaa gaaaaaaata tcgattacct
    35341 cccttagttc ctgctattct gtctaattca aatgactctc caccaaaatc aatcattaaa
    35401 ctatccaaat caatctctaa acgttgacca tccaactcgg ctataccctt agatattcct
    35461 ctcagcttca ttggtttagt gattgcttct attgctaact gcttcattat ttccccctat
    35521 atggaaaaac ccaaaactat tgacttgata gcaaaaaggg gattgctccc ctgtattcta
    35581 cttcaaatgc tctgtataac cagcaaggcc tttatattcg ccctctacgt ccaacttttg
    35641 gagtaggcta atactttcat cgcccagcat ttccaacgta gcaaaagcag tcatagagtc
    35701 catagggata ggcttatcag aaagcaggcg gtcagcatag tctaatagtt ccagctcgta
    35761 gtctgtgacc ttattcagta aactctcaaa gtcctctgac tctttgagtt ggagcacgcg
    35821 ctcccgtttg taacgttctt caaatgcttc agcctctcct ggttgtttgt ggtagtcttt
    35881 aaaactgtca caaatacgct taaaggtctt gtttagcttg tgatcttcca catactcagc
    35941 tactagcgtg cctttatcct tgtaggtcaa tgagattaca ggctggcaat atgttccagt
    36001 catatatccc agtaacgcgt gacctgctac cagagctgta tctaggtctt taaattcgta
    36061 agtgaaagta aatgttttgg ctttagatga aaatgttttt aatgtcatgt tgtttttcct
    36121 ctttctgttt ttaagggtgt cactagtagt tacaccattg caagggggtc ggtactatct
    36181 accccatttt gttatctgta taataccaat acggtagcca ccgaattaaa ggattcacta
    36241 gatggtgtac cagaaaattt aacgtccagc acttcaacag ttgccatgaa gtcatcgatc
    36301 tctttctcaa agtcttcttt ttcccatcgt ctagtatatt caaatagttt aactttcatg
    36361 ttgttgtcat ttctttgttt taaggtaaat tatgtaatat ttttcgtttt ctgtgacctt
    36421 ctgtgacctt ttgtgacaaa gaacgtcaca cgttcaaacc cttgaggctc taggtgtttc
    36481 accacccctg tgaccctgtg acgttctttt gttttatcgt tcctatatat ataaatactg
    36541 tatttttctc tatatataag agttggaaag aatgtcacaa cgtcacacct attcccctaa
    36601 agttagatat atcaaggctt caaggggtgt gaccttcttt tttgagaacg tcacacaacg
    36661 tcacactttt ttcaagaaaa tcagtattat caagggttta agcaaaaaaa gaacgtcaca
    36721 cttattcttg tttagtgata gagtgttgag gtgtccgcat ttttatcttg tcaacgtccc
    36781 atgcctctag tttttcaaaa tcttctggag aaactctttt ctttcttaga gaataccgat
    36841 taggtgtcaa ctgttgtaag tgcttgatag tttctttacc agccccgtaa acattgggct
    36901 tgggtattcc catatcttcg gcatagtgct ttagtgatct tgtaacgata aaaacaggta
    36961 ctacgtccag ctcatgccaa cctttttcca tgtattcatg cttaacccat gaaagtaagt
    37021 agtcattatc ttcctggtat tcttctagga gtcctttaac tgctttaggt tcgataaagt
    37081 gagtaaatgg ctcttgattg atagctttgt agagggcata ttctaggact tccttgtttg
    37141 ctaaaaactc attttttatc caaggttttt ccttctcccc gttaaagtca gcattaaaag
    37201 ggacaatcat aattctacga taccagcctt ttgtcttgtt gccaccattg gggatataat
    37261 tccctgaaaa gatattgaat aacttgaaag tagcttcaaa ggctgggcgt ccttttggat
    37321 tgactagaac agtgtcgcca ctagtgatac tcattaaatc agacggattt tttaagtatt
    37381 cgttaggtgc ttcatcccca atattacaaa ccttacctac caaggtctcc aagttatgct
    37441 tttcagcaaa ctgtgcaggc tttaaggctg atatattgct ttcccctatc aggttgataa
    37501 ggaagcgctg aaatgtccct ttaccattgt taccgtcccc gtagaagata gcaaacttat
    37561 ttcgagtatg gttagggtta atagcttcaa ggataatctg ccaaaacagt gttaccagtt
    37621 cactatcatt acaagcgatt gagttcaacc aatcatcaaa agtttttccc tctctatctg
    37681 ttgggactcg tttaggcgcg tggtaggccg tgcttatctt acttgtaatt acatacttag
    37741 gactaaaggg gagtagttcc ttagtttcta agttgataat gccgttctgt acgggaatga
    37801 ggttagcact ttctaaaggt tttcgtatct ttgccaatgt tctaaccatt aacttaatct
    37861 gtggccactc tctgggttta attctaacgt caaaggtctt acacaaaaga ttgaatagat
    37921 cattactagc ggtatagata ccctcgtcta aatcatagat atagagtagg ctataatcag
    37981 gtatattgct cttgctgata aaagtaaatg tgacaatctc gctcagtatt ttagctactg
    38041 tgaaggtttg gggcatggca accttttcgg taacgtcccc tgtgttctca tttaccttag
    38101 tttcagtatg ttctgcccgc cattcttctc cagctttaaa gatacgattt tcaagctcct
    38161 tcatcgttct aggagggtgt tcttgctcca ttacctccaa gatttcactt tttaggtttg
    38221 ctaattcttc tagttctatg gttctaacct ctctttctat attcagcccg tgctatactg
    38281 ctaaaagtgc ggtctagctc ctcaatcggc aatggttcaa ctgtcacgct attggctatc
    38341 tttgtaagtt cataggctgt ctctaggtca caatcaaccc acttattaaa gagtaagcct
    38401 acaaatcgtg tcagtgctac gttgcgccct ccctcgtctc caaatccgtt gaaaagcgtg
    38461 tcaatgatcc tcatggtcat agatttctgc ccgcttggcc ttggagtgta tggaaggctt
    38521 gccgcattct gtttgactgg ttcagccgtt gtctgtggta ctggataatc aagtccatgc
    38581 tctacaatct tttgataact tgctgggtcg cctgttgtga ctggtagccc ttggagttgt
    38641 gaccatgtta aactggccat atcaaagggg agtccaatct tgtcagcaat ctctttcact
    38701 acctgcttat aggtcgcctc attcatcacg ttgtcaggct tcactacaag gcgaaaacgg
    38761 ggcttttcta agctatgttt gatagtcggg tataagatgt aagagtagcc aaataaagcg
    38821 ctagaaatgg cttttataaa gccctcagac gtcccctgta tatcgtcata atcaaggaaa
    38881 atcaaatccc gatagattag actggagttg tttcgcttgt aactgccatg cttttctggc
    38941 gtcactttgc cacttataca gtaaggcgct tgagttcgct tgtattcctc aatatctgcc
    39001 ccttcaggaa ctactaaggg cttgaatcgt tcaatatact ggaaaggctc aattttatca
    39061 aatggataga caagattact ctgaaagcct ttagcctcat aaattgtcat actatcgccc
    39121 ctttttgcgt tttttcttca gctttttaag cctttgctgt tcctttagct ggtctagggt
    39181 tggcctgcgc tctttgtaaa atttaatatt gtgataatgc cctttattat ctgccggatg
    39241 aatactatac cttgccattt tccaccccca aaaacttcca gatgtcagat attttataat
    39301 agattttcct agtatcttct agcggtggct gataccgtct tagccctgct ttttcccact
    39361 tttggagtgt catgtatttt atatctaact cgtccatgac ttcctgggct gatattaaac
    39421 ctgtcagtcg cggcttgact gtatcacgcg cttccaggta tctttctact acctccagaa
    39481 tgccatgcgc taggtcttgc tcactttctc ggcttaggct aaacatatcc gcccacctcc
    39541 ttcaaggttt ctttgtaact ctctaaatca gcattcaaaa ggacagttag gcgtttctgt
    39601 tcttcctgta cttggttata gaatgccttt gctccgtcca gtagctcctc tttgttagct
    39661 gggataaaat atcctctaaa tgtcccatgg cgaaccccaa caataggaac actatgacgc
    39721 gtgattagac ggctgataat atcttgtacg gttctttccg ccagcttagt tataaggctg
    39781 atttctgccc ctgttatgga gttctcagcc cctaccttga ttagtcttaa tactcgtttg
    39841 tcattctctg atagactcat tcagttcctc cgtaaactct tacccctgca agctggatat
    39901 aacgcccata atcagggctt aaatcctcgc taggtgtttc tatcctctgt tggttttctc
    39961 gctcaaattg ggcgcttttt ttgcggtctc ggtggtttag gtaaagcagt aagccaatca
    40021 ataccaccat aaagattacc gattgtgtat tggtcaaatc taactcattc atgttatgcc
    40081 ctcgcttgat aattcttgat aaattccact tgtttttcat gtttcatctt caggtattcg
    40141 tctacctcct cagtgcttac ttttcgatct acaaaatcag caataaactg gaagaggttg
    40201 gggcgttttt ccttaatttc agccattact tcatcaaact ctgcttgtgt catgttgtct
    40261 aggtttagtg tcattgcatt gcctcctcaa acttctctat aagacaactt ttatttactc
    40321 tctgagttcc atttttagag ttaaaaagaa tatcttttaa ggttatagta gcctctaaat
    40381 actccttttc agcatgttct atatacgcct gttgctctgc ttcgttgtca aaaaagtgca
    40441 tagcttggcg tttaaagaat gcttgtcgca tagcgtccat ttcaaaaata ccagcgtgga
    40501 aaaacattcc cgtagtgctt ttagaaactg cctcgatttt atggctgtca ttcaattcag
    40561 gaagttcaat ccaaagtaaa cggtgtaaat tttctttgat gaattttgtc tgatttgcca
    40621 ataatgaaag tctactaagc ccattttttt cgccaatttc tcgcatttct gcgctaattc
    40681 tgtctatatg tctagttaaa ttctcgtatg ttgtttctgt catgtttttt acctttgttt
    40741 ctatgttgtg taattgctct aagagctttt aatgcctttt actatactgg atatcctcac
    40801 gctcagaagt ttgccgaccg agagtgtggg ggtttttaat ggttgtttct tatacagttt
    40861 ttcttgcaat tcatagcctc acgctctgag tcgccaaatt gagagcatga gaaagtacca
    40921 gtttaaagag ttggcgctct ccgtatggtc aaattgccct aaatatgcta taatctaggt
    40981 ataaatcttt actaaaacct ctttgataat agcttgcctg ctttgttaaa ttcgttttag
    41041 tgttagtgtg aaaggctctg cggtgtggtt attgctaagc cttttttgtt gctctcacgc
    41101 gcttctttgg cgtgtttttt tatttctgaa tgccatagcc ttgatttctt ggtaactcat
    41161 attcaagccg atcatggcta ttaccatatc ctcaaatgcc tggtattgct ccagctcgtc
    41221 actggtcaag ctatcaatac cgttatagcc cccacgttct tcccttaact gcttagcgtt
    41281 catgtcagtt actgctttta gtagcaggtt gttcatggtg ctatgcgcgt gcttgggttt
    41341 tgcctcccat gtctctatac tgtcatgcaa ggtttttctt tttggctttt ctagcgccct
    41401 ctgcatacgg aacttagaaa gctcctcacg catttcaaag aatgctttga ccaggttctt
    41461 cttaaactct tttacgggtt ctgtatttcg taagtaagtg atcagcaagg ttgcttgttg
    41521 ctcattcaaa atatagtccc gtacattttg cccactttct gaaggtgaaa ttttaaattg
    41581 cacctttccg aaactctcga agtcctctcg atgtttattc agcaaaatct tcaaatgtct
    41641 gtgcttaact tctgcacact ccgcaacaat actgctcagt gtatacggct ctttcttacc
    41701 gtccatgtag actaattcca ttggtttgct cctttcttag atttcctttt gatttagttc
    41761 tatttttttc gtactatctc ctaaaaaata tcgtccagtt ttacctgata cagttccgat
    41821 aactctttaa gtagctcaaa agggattagc gtactatctt tttcgtactt tgagatagtc
    41881 tgaaaattct tgttgacctt cttagccact tggcgcaaag taaaacctgc atttactcga
    41941 cacgctctta gcgtccattg tgccatattc ttatagctcc tttcaagatt gataaaatca
    42001 tggtactatt tttttcgtac tttgtcaacg ctgttgttga aaaattttat ttttttcgta
    42061 ctttgtcttt tttgtgttat aatcaggttg tagaattaaa gtaagggagt ttttaacaat
    42121 ggcaaaaaat agccctcagg atttaaagaa tagagaatat ttctctaata atcttaaccg
    42181 tgttatgaaa gaaaaaggta tcagacagat agacctgcat aatgctttag aaattcctaa
    42241 aagtacaata actggttatg taaaaggtag atcaatgcca acatctggca atcttcaaaa
    42301 acttgctgat tatttgggag tgaaaaaatc tgatcttgac cctcgctttt ctgacaaaga
    42361 tgtttacaaa gaatttttat atatgttaga taaacaatta gacgaagaaa aatacctcgt
    42421 aaaaaatgtt tcaaaagata aaatttttca gaaagtaaaa gagagagaga aaagagacaa
    42481 ggaaataatt gaactagcaa agagtaaaaa tttcccaatc agtcctgaag agtttctcac
    42541 tactatcact gaatcattaa atgaatacaa tcccaaagac aactatgaag ttttaaatgc
    42601 ccttgcgcta aagacaagta atatcctatt ctggctagat attgtatttc aaaaaacaag
    42661 tagtgaattc tacatagttt ttgaagataa ggaattcaac caagaatatt acaacaaatt
    42721 atataaaaag tttgaaaatc tatttgaaga aattaagtct ttagctcttc aagaagctaa
    42781 gaaagataaa gaaaatctag atgattttgc gttactttgg ggtatagact aacccacgcg
    42841 ccacaatgtt caacaatcct gaagcgcgtg tgcgaatgcg tgtgcgaata atctactttc
    42901 aaaaaaacct ttaatagcac tgttagctaa ctaaaaataa actatttttc ccgcgcgtgt
    42961 gcgaatgcgt gtgcaaattg attggagaaa aaatgagaaa atacgatata ccaaaattgt
    43021 tattatcagg ggagaaccaa ggtgttgaat tcaaagaagc taaaaattct ttccctaaag
    43081 acggtatgaa aacaatttgt tccttcgcta atacaaataa tggtctgtta attctaggtg
    43141 tctcagagaa tacaaagaat aaagattttt atatttctgg agttaatgat cccgataaag
    43201 tactggacga attatatagt ttacttaata accctaataa aattaataga aatgtgatta
    43261 atgaagaaag tgttgaagtc gtaaatataa aaggaaaaga gattgtcatt atccctgtta
    43321 acaaggtaga ctacaaggat aaacctatat atcttaatga caacatcgca tctacctatt
    43381 ttcgtcaggg gactggtgat tttaggtgtt cacaagagca aatcaactct atgttaagag
    43441 attccgctaa ggaaagtttt gatagcacac ttattcagga tttttctatt ttagacttag
    43501 atacagaaac aataaagcta tatagagaaa aatttgataa tataaatgcg gagcaccctt
    43561 tttcaaagtt ggataacgaa caatttttaa taaaaataaa tgctttacga agagatcgca
    43621 aggacgataa aataaagcca acagttgctg gactattaat ttttggtaca cataattcaa
    43681 taaaagagtt tattccacac tataacgtag aatatgttct aaaagagttt tctgaaaaca
    43741 atcgctttaa agatcgtgtg atttatgatg gtacatgggg ggaagataat ctttttaatt
    43801 tcttttacct agttattgaa aaattatatc taactttaaa tgacaactct aacattcaag
    43861 aaaattctat gaatagaatt ggaatttcaa aattacgaat tgcaattcgt gaggcattca
    43921 ttaatagcct tattcatagc gactataaaa gcgaaaaagg gataatgata attagatatc
    43981 ccgacaggta tatattcaca aatggcggaa cacttagaat tgacataaag gactttttta
    44041 gtggggcaca ttctgatcca agaaactact taatacaaga aatttttaga tttttaaatt
    44101 tatgtgaaaa agcgggaact ggtataccca aaataatgga agcagttaaa gagagtcatt
    44161 taaaatatcc caatttacga actgaattag actcagttga atttacatta tgggatactt
    44221 cccttataga taatctggat attgataacg aatatgagaa aaagatatta gagttaataa
    44281 tcgaacaccg tttcgtaaca agagaggctt tggaagaaaa actaaaaatc cacaaaaata
    44341 caattttaaa atatttaaaa aaattagtgg aaaaacaagc tatcgataaa ttcaaatctg
    44401 gtagacaata cgtatacttt attacacaaa accaagatcc tgaatttcaa aaatataacc
    44461 acattaatgc tatgtattct ttactggaag aaataaaacg aaaataaggg ggttctcgta
    44521 gctcctagca tgatataaaa cctttttgat aatggcttgc ctgctgatgt attttagaaa
    44581 ggtttatcat catgaaaata actgaagtta taaaaaaaga cggtagcaaa gtttatcgtg
    44641 ctaatgtata tctaggagtt gaccaggtaa caggaaagaa agtaaaaacc aaagtaacag
    44701 gtcggacaca aaaggaagtt aagcagaaag ccaatcaaga aaaaatagct tttcaaaaag
    44761 caggatctac cagacaaaag gctgttacca taaaaaacta tcaagaattg gcaactctct
    44821 ggttggaaag ttataagaat acggttaagc caaacactca aggcaatgtt aaaaagctaa
    44881 tcgataatca tatattgcct atttttgggg cttacaagct cgataagctc actactccac
    44941 ttatccagtc aattatcaac gaacttgctg acaagactaa tagaggggaa aaagcggctt
    45001 ttctacatta tgacaagata cacgctttaa acaaacgtat cttacagtat ggcgtaacca
    45061 tgcaggctat accgtccaat cctgcgcgtg atgttgtttt acctcgtaac actcagaaag
    45121 caaagcggaa aaaagtaaag cactttgaaa atcaagaact aaaaaaattt cttggttatc
    45181 tcgataattt agatactcat agatatcgtt actactatga gacaacactc tataagttcc
    45241 tattggctac tggttgccgt atcaatgaag ctttagctct ttcctggtct gatattgact
    45301 tagataatgc cgttgtgcat attaccaaaa cactaaatcg ggatatagaa atcaatagcc
    45361 caaagtctaa ggctagttat cgggatatag atatagatca agcgactgtt agcatgctga
    45421 agcagtacaa actacgccaa actaaagagg cctggaagat agggcaacgt gaacgcgtgg
    45481 tattttctga tttcattcat gagtatccta gcagttcaag acttaaaaga agattgcaaa
    45541 cacattttaa gcgtgctgat gttcctaaca ttggatttca cggattccgt cacactcacg
    45601 ctagtctctt gcttaactct ggaataccat acaaggaact ccagtaccgc ctaggtcatt
    45661 ccactttatc aatgaccatg gatatatata gtcacctctc aaaagagaac gcaaaaaaag
    45721 cagtatcatt ctacgaaact gcactaaaag cactataggg ggagcaaaaa ggggagcaaa
    45781 tttaaaaatc aacatttcaa gacaaagtaa aaatccaata acaacggtgt ctttgtaaga
    45841 ttttatttga aaaaagccga ttttgtagta taatagtaca gtgtgaaaaa atctgaaaaa
    45901 tgagaaagga taagggatat gaaacaagtt tttctctcta caacaactga atttaaagag
    45961 atcgatacgc ttgaaccggg tacttggatc aatctcgtca atccgactca aaatgaatca
    46021 ctcgaaatcg ccaacacctt cgatattgat attgccgacc ttcgagcacc gctcgatgcg
    46081 gaagaaatgt ctcgtattac cattgaagac gagtataccc tgattatcgt agacgtgccg
    46141 gtcacggagg aaagaaataa ccgcacctac tacgtaacca tcccgcttgg tattatcatc
    46201 actgaggaaa ccattatcac tacgtgtttg gaaccactac ctgtccttga tgtctttatc
    46261 aaccgtcgat tgcgtaattt ctataccttc atgcgttcac gttttatctt tcaaattctt
    46321 tatcgcaatg cagagcttta cctaacagcc cttcgttcaa tcgaccgcaa gagtgaacaa
    46381 atcgaaagtc aactgcatca atcaactcgt aatgaagaat tgattgagct catggaattg
    46441 gaaaaaacta tcgtctattt caaggcctcc ctcaaaacaa atgagcgcgt gattaagaaa
    46501 ttgaccagtt caaccagcaa tatcaagaaa taccttgagg acgaagacct gcttgaagac
    46561 accctgattg aaacccaaca ggccatcgag atggcagata tttatggaaa cgtcttgcat
    46621 tctatgacag agacctttgc ctctatcatt tctaacaacc agaacaacat catgaaaacc
    46681 ttggcccttg tgaccatcgt catgtccatc ccaaccatgg tcttttctgc ctacgggatg
    46741 aactttaagg ataatgaaat tcccctaaac ggagagccaa atgccttctg gttaatcgtc
    46801 tttatcgcct ttgctatgag tgtctcgctc actctctatc tcatccataa aaaatggttc
    46861 taagaggagt tcctatgtct caaattgatc tacaaaaatt aactaagaaa aaccaagagt
    46921 ttgttcacat tgctacccaa caattcatca aagatgggaa aacagacgct gaaatccaga
    46981 ctatttttga ggaagtcatt ccccaaatcc ttgaggagca atctaaaggt acaactgccc
    47041 gttccctata cggcgcacca actcattggg ctcatagctt cactgtcaaa gagcagtacg
    47101 aaaaagagca tccaaaagaa aatgatgatc caaaactgat gattatggac tcagctcttt
    47161 tcatcactag cctctttgcc cttgtcagcg ccctcacaac cttctttgcg gcagatcaag
    47221 ctttcggcta tggattgatt actcttctat tagttggact ggttggtgga tttgccttct
    47281 acttgatgta ctactttgtt taccaatact atggaccaga tatggatcgc agtcaacgtc
    47341 cacctttctg gaaatctgta ctagttatcc tagcttctat gttcctttgg ttgcttgtct
    47401 tctttgcaac aagcttccta ccagctagcc ttaacccagt actggatcca ttgccactag
    47461 ctattattgg agtagccctc ctagcccttc gcttctatct caagaaacgc ttgaatatcc
    47521 gtagtgcaag tgcaggacca acacgctatc aagaataaga aaacgataaa agcaactgca
    47581 ggtgcggttg ctttttcact tacttttttg agttatactc aatgaaaatc aaagagcaaa
    47641 ctaggaagct agctgcaggt tgctcaaagc acagctttga ggttgcaaat aaaactgacg
    47701 tggtttgaag agattttcga agagtattaa aagtattctt ctgaaatccc acatagcttt
    47761 ctcttatatt ttgtgataaa ataggctcaa tctatttcta ggaggatgag atatggtttc
    47821 tactattggt attgttagtt tatctagtgg cattatcgga gaggattttg tcaaacacga
    47881 agtggacttg ggtatccaac gtctcaagga tctgggactc aatcccatct ttttgcccca
    47941 ttcgttaaaa ggattagact ttatcaagga ccatcctgaa gctcgtgcag aggatttgat
    48001 tcatgccttt tctgatgata gcatcgacat gatcctatgt gccatcggtg gagacgatgc
    48061 ctatcgcttg ctaccttatc tttttgaaaa tgaccaactc caaaaggtta tcaaacaaaa
    48121 aatttttctt ggcttctcgg atacaaccat gaaccacctc atgttgcata aattaggaat
    48181 caagactttt tatggtcaat cctttttagc agacatttgt gaattagaca aagaaatgct
    48241 agcctatagc cttcactact ttaaagaatt gattgagacg ggaagaattt cagaaatccg
    48301 ccctagtgac gtttggtatg aggaacgaac tgattttagt cccacggccc tgggaacacc
    48361 tcgtgtcagt catacaaata caggttttga cttgttgcaa ggaagtgccc agttcgaggg
    48421 gaaaatcctc ggtggttgcc tcgaatccct ctacgatatc tttgacaact ctcgatacgc
    48481 agatagcacg gaactctgcc aaaaatacaa acttttccct gacttgtcag actgggaagg
    48541 gaaaatcctc ttgctcgaaa caagcgaaga aaagcctaag ccagaagact tcaaaaagat
    48601 gttgctaact ttaaaggaca ctggcatatt cgcggtcatc aatggactct tggtcggaaa
    48661 acctatggat gaaactttcc atgacgacta taaagaggca ctattggata tcattgacag
    48721 caatatcccg attgtctata atctgaatgt cggccacgca actccaagag caattgtacc
    48781 ctttggggtc catgctcatg tagatgcaca ggaacaagtc attctctttg actataacaa
    48841 ataaagctgg gaaaagtttc tcagcttttt tctcggtatc attactggca ttttcatcac
    48901 atattacagt atattgaaac tagaatagta cacctctact tctaaaacat tgttagaaat
    48961 cgatttgtcc tgttctcatt tcattttact atactgatag ctaaaatgat taaggagagg
    49021 ctgttgctta acatgtgaac aagtagggga tagtagatat tctctttttc tttcacataa
    49081 ataatagaaa aggcaaggcc tccacctaag taaccaactg caccaatcca ctctgataga
    49141 gccaaactgt gcatatgagt caaagcaaaa acaagtccta ccagaataat gcttagtaaa
    49201 cctgacaacc gttcctgcaa gtaatgcaat aagacctgac ggaaaaataa ttcttctacc
    49261 agaggtccaa tgacacaagc aaaaacagct atcagtagtg gttgttcttg aaaggtactt
    49321 tgaatattag actgatttag accttgtcca tctagtccca caaactgctt caacatctct
    49381 gatacaaatt caaagacaac agtcatcaga atgagaaaga gccatcctgt taagactcca
    49441 aagaagaatt ttcttttagt ctttctaatc tccttccatt gttggatcaa tctatccttg
    49501 aacaagaagg agccatataa agctaaaact acataaacaa gataatttgc aatggcagat
    49561 ggcattaaag aagccagcaa tttaacgcca tcaaacacaa agaggactgt atagagaatc
    49621 acaaaaatca gaattccctt atttttgtta gacatcattt aagacatttc cactcacaat
    49681 cattctcgtg gtcatcaact agccctgcag cctgtagaaa agacaatacg gcgactgggc
    49741 ctgtgaactt gaagcctcgt tttttgagat ctttggctaa tttctcagat aagggtgttt
    49801 tagctgggga ttggcgataa tcaggaacat cgttaacgac agttttcccc tcaacaaaag
    49861 accaaagata ggcatcaaaa gagccgtact ctgcctgtaa ctgtagaaag gcttgggcgt
    49921 tagcgcgtgt agcaaaaatc ttggctctat ttcgaatgat agctggattc tccagcatgg
    49981 cttccaattc agtgtcagtc atctctgcga ctgagtgaat ttgatagcta tgaaaggctt
    50041 ctcggaaagc ttggcgtttg ttgagtaccg tttcccaaga caggcctgcc tgataggttt
    50101 ccatacacaa caactcaaac aacgcttggt catcatggag gggctggccc cactcctcat
    50161 catgataggc gatgtagagt gggttggtca tcttgaccca cgaacaacgt tttgtcattc
    50221 tctgctccta tttgaccaac attttaaggg ccgacttgat atagttctca gctgtatctg
    50281 tcgttccttc aaagaatttc ttgattttct tgagctctgt tgccttgtag cccagagcca
    50341 acatggcttc catagcttct tccaattctt ggttttcagc acttgcttgc actgcgacct
    50401 tggcaggaag gtcatctcct gcaactacta ccttgccttc caagtccagc accatctgct
    50461 gggctgtttt cttgccaatt ttagggaact tggtcaagta ggtgatgttc ttggtttcaa
    50521 tggcttgaac caagccagca ttgtcatcag cagcgataat agcaagagct gatacaggac
    50581 caatcccaga gaccgaaatc agactaagaa agagcttttt ctcatcctct gagcgaaatc
    50641 cataaagcaa atgggcgtcc tcacgcacaa cctgatgcac ataaatctga gcctcctgat
    50701 taacctgacc tgaataggca taaggattgg ccacatgcag gatataacca ataccattgg
    50761 tttcaagaac aatgtatttg gcagtaattt tggtaatgat tccttttaaa tatgcgtaca
    50821 tagtgttcct tctctcttat ttcgtttatc tagtatatca tattttcttt atccgaggag
    50881 cgagaatcga ttatcacaaa tacagtatat caaaaacaat cggtatttat ctgttgacat
    50941 attcaaaatt aagtactata atcatctgta attgaataac tatcttcagg gcagggtgca
    51001 attccctacc ggtggtatag cccacgagcc gaaaggcatg atttggtgaa attccaaagc
    51061 cgacagtata gtctggatga aagaagataa aagtatattt gtgctttttg cgtgctctga
    51121 aatgattact tgtcatttca gagcattttt gttaatcgca taagttttct tttgtatgcc
    51181 ttgagtagtc ccctattcaa ggtatatttt tttggaggta gtgagatgag cgattcaaaa
    51241 tatatgaaat tagcaataaa actggcacaa aaaggggctg gttacgtcaa tcccaatcct
    51301 atggtcggcg cagttattgt aaaagataat cacatcatcg gacaaggtta tcatgagttt
    51361 tttggtggcc cacatgctga gagaaatgct cttaaaaact gtagagaatc ccctgtcgga
    51421 gcgacgcttt atgtaacact tgaaccctgt tgtcacttcg ggaaaacacc tccctgtata
    51481 gatgctataa tcgatagtgg tattacaaga gtagtcattg gaagcctaga ctgtaatcct
    51541 attgtatctg gaaaaggagt aaagatactt gaggaaaata atcttcaagt tactgttgga
    51601 attttagaaa atgagtgtct taacttaata aaaagtttta gaaagtatat tacccagcat
    51661 gtaccctatg tttttatgaa atatgcaatg tcaatggatg gaaaaatagc cactaaaaca
    51721 aatcaatcca aatggattac tgaagaagaa gcaagaaagc atgtgcatca gttacgacac
    51781 tatgttagtg caattatggt gggagtcaat actgttattc aagacgatcc tttgctgaca
    51841 tgtagattgg aggaagggaa aaatcctatc cgtatcatat gcgatacaca tttacgaact
    51901 cctcttacct ctaaaatcgt aaaaacagca aatgatatta aaacttacat tgccacttcc
    51961 tctgaagaca aaaataaaat gaagctatat caaaatcatg gctgtgaaat actttccata
    52021 aagaaaaaag gcaatcatat agacttatcg agtttaatgc aacatctagg aaacatgcag
    52081 attgatagcc tagttctaga agggggcagt ctaatgaatt ggagtgcttt ggaacaacaa
    52141 attgttgatg agctgaaaat atatattgca ccaaaaattt ttggaggcag tgccaagttt
    52201 cctgtcggag gtgaaggcat ttctttgcca aatgacgcta ttagattgaa accttatgct
    52261 ttttctcaaa taggaaatga ctatctcata gaaagtgaag tgatttatcc atgttcacag
    52321 gaataattga agaaatcgga aaagttgaaa gaatacagaa agactctcgt aattgtaaac
    52381 tatcaattaa agcctcaaaa atattaacgg atatccattt aggcgatagt atagcagtaa
    52441 atggtatctg tcttacagtt actcatttca atcatcaatc ctttacagtt gatgtaatga
    52501 atgaaacatg gagtcgaaca gctcttactc tattaaaaca tggaagtgag gtgaatctag
    52561 aaagagcctt atctgtcaac ggtcgacttg ggggtcacgt cgttacagga cacattgatg
    52621 gtacaggaaa aatctcgtca ataaaaaaag atgataatgc tgtatggtat caaatcaaca
    52681 cacaaaaaga aattttagat ttaatagttg aaaaaggatc tattacaatt gacggcatta
    52741 gtctgactgt cgctaaagtc tccaaagtaa acttttcagt atctgttatc cctcatacct
    52801 tgaaacaaac cattcttaag agtaaacaag tcgggagtac agtaaatctt gaaaatgata
    52861 tcttaggtaa atatgtgcaa aaactgatgg ataactctcc aaaatcagaa atatctaagg
    52921 aactattata tcaaaatgga ttttagcaga aaggataatc agtcaatgga atatcgaaaa
    52981 atacaagaag cattagaagc attgcagaag ggacgacttg ttcttgttat agacgacaag
    53041 gatagagaaa atgaaggaga cttaatttgt tctgcacaag cagctacaac agaaaatgtt
    53101 aattttatgg ctacttatgc caaaggatta atttgtatgc ctatgagcga aagtttagct
    53161 aatcaattaa tgctttcacc tatggttgaa aacaatacag ataatcataa gactgctttt
    53221 acagtttcaa ttgattataa agaaacgacc acaggtattt ctgccgagga aagaggactg
    53281 accgcacgta tgtgtgtagc tgaagatata acaccctctg attttcgcag gccaggacat
    53341 atgtttcctt taattgcaaa aaaaggtggt gttctagaaa gaagtggaca cacagaagca
    53401 actgttgatt tattaaaatt agctggacta aaagagtgtg gcctatgttg tgaaataatg
    53461 aatcatgatg gcaaaatgat gagaacagat gatttaattc agttctcgaa gaaacacaac
    53521 attccactaa ttaccatcaa agaattacaa gaatatagaa aagtatatga tcagctggta
    53581 gaacgagttt caactgtcaa tatgcctact agatacggta atttcaaagc aattagctat
    53641 atagataaac taaatgggga acatcatctt gctcttatta tgggaaacat agaggatgaa
    53701 gccaatgtat tatgtcgggt ccactccgaa tgtttaacag gagatgtttt aggctcttta
    53761 cgttgcgatt gtggacagca attcgataaa gctatgaaaa tgattgttga gaatggttcg
    53821 ggtgtcttac tttacttgcg acaggaggga cgaggaattg gacttatcaa taaattaaaa
    53881 gcctatcatt tacaagatca aggcatggat acgcttgatg ccaatcttgc attaggcttt
    53941 gaaggtgatt taagagaata tcatattgga gcacaaatgc ttaaagatct gggacttcag
    54001 tcacttcatt tactgacaaa taatcctgac aaggttgaac agttagaaaa atatggaatt
    54061 accatttcca gtagaatatc aatcgaaata gaagccaatc cttacgatag tttttattta
    54121 gaaacaaaga aaaatcgaat gggtcacatt ttaaatatgg aggaaaaata aatgaacact
    54181 tatgaaggta atttagtagc aaacaatatt aaaataggta ttgttgtagc gagatttaat
    54241 gaatttataa cttcaaaatt attatctgga gcactagata atctcaaaag agagaatgta
    54301 aacgagaaag atatagaggt agcctgggtt ccaggagctt ttgaaatacc actgattgca
    54361 tcaaaaatgg caaaaagtaa aaaatatgat gcaattatct gcttgggagc tgtcattaga
    54421 gggaatacaa gtcattatga ttatgtatgt agcgaggtat ctaagggaat cgcccaaatc
    54481 agtttaaata gcgaaattcc tgttatgttt ggtgtgctaa cgacagatac aattgaacaa
    54541 gccatagaac gagctggcac taaagcagga aataagggtt ctgagtgtgc acaaggagct
    54601 attgaaatgg tcaacctaat tcgtacatta gacgcataga acagactcta cttttagacg
    54661 aataaagaaa cttggcaaaa tcgcaattta atactctgtg aaaatcatag agcaaactag
    54721 gaaaccagtc gcagagtggt caaacacaac ttcgatgtta cagacaaaac tggcaaaatt
    54781 agctcaaaac actgttttga gattactgat aaaactgacg tggtttaaaa agagtttcga
    54841 aaagaattag gaaaacatga agtaaatatt tctatgataa aacgcataaa atcaaggttt
    54901 ttgaacacct gattttatgc gtttttctga ttttgaaaat ttttcccaga cttttttata
    54961 cttttaatat ttccccaact cacggagact ggtgtgattt tcctgaatac gtcggaacat
    55021 cttttccata tccgacttgg taaaatgcac caaaacagga cgtccgtgag gacagttata
    55081 gggattgtca cattgagaaa gctgatagag gagttgtcta gctgaatgat catcaatacg
    55141 atgattggcc ttgatagatc gcttgcaaga catcatgata gccagctctg ctcggtattt
    55201 cttgatagaa acttccttgg tcaaaaggag catgtcgcac atctcataga tgcctgattc
    55261 aatctcttct tctgccatcc aaataggatg ttcacgtaga ataaattgat tttctccgta
    55321 ctctgctaga aagacgccca cttcctctaa gagaggcatt ctttccttga gacgcagggc
    55381 atcatccgca ggaaattcaa agatataggg cactaggagt tgctgctggc tctggtcaac
    55441 attgccaatg ctttcacggt actcctcgta cttgacccgt tcctgagcag cgtgctgatc
    55501 tatgatgtaa agtccatctc gcccttgggc aaagagataa gtcccgtgca tttgtccgaa
    55561 aaactccaac tctgggaagc tggatgcttc ttctcgctcc agtttgtcat aagccttatc
    55621 gatgctagca agatctaact ctggatggtc tagctggtcg tagttagcag gctttctctc
    55681 tgcaaaatgc agttttgctg gcttggtcaa tcggtccaag gtttccttgg caaacagggt
    55741 caaatcctgc ccttcatcag tcaattctac ctgataatca gctacttcag tttgactagg
    55801 tcttgacggc tcagttttct catagtagag cgtattttct ttgagtggga gaatagtttg
    55861 ctccaccttc tcacgattgc gcacggtcga tttggcaaga ttttccaagg catctggaat
    55921 caaggtttgt tccttgagac tatttgcaat agcttctgaa accagggtca tcagttcttt
    55981 ttccttggaa atccgcacct cttgcttagt tggatgcaca ttgacatccg ctagataagg
    56041 gtcgatatgg atgtgaatga cagccagtgg aaaacgtcca accataagct tgcttccgaa
    56101 accatccaaa atagcacgat tgagcaggaa gttcttgata taacggccat tgatgaagag
    56161 gctgatataa ttgcggttag cccgagtcaa ctcaggtaaa gacacaaaac ctgaaatttc
    56221 gaaatctagg tcagagttct caatttcaat catcttcttg gcactgacca aaccgtaaat
    56281 ccctgcgatt gcttggcgca attgaccagt ccctgctgtc cgcgtcattt ccttgccatc
    56341 actaatcaag ctaaaagaaa tctcaggatg ggccaagccc agacggttga caatatcaat
    56401 gatatgagac aactccgctt gctggctctt catatacttg agacgggcag gcgtgttgaa
    56461 aaagagatcc tccacacaaa ccttggttcc cacaggacta gtcgctggga tgacttcctc
    56521 aacttcaccc ccacgcgcga ctaacttggt tccatgacta gcaccatcca ccgccgttaa
    56581 cagagtcaag acactaacag acgcaataga aggcaaggct tcaccacgaa aaccaagcgt
    56641 ccgaatccga aagagatctg cttgattttt tatcttactg gtcgcatggc gacgcagggc
    56701 caactccacc tcatcgtggg caattccatg accgttatcc gtgatttgaa ccttcttgag
    56761 accagcttcc tcaatctcaa tgataatctg actagagccc gcgtcaatgg cattttctac
    56821 caactcttta accacactgg caggacgttc aatgacctcc ccagctgcga tttggtttgc
    56881 cagcatctct ggcaattcaa taatatgaga catctttcag cccctttctg tatctatttt
    56941 cctagaaatt aattagtgct attataccat atttcagaaa gaacagaaaa actccaccac
    57001 ataggagccc aatccctcca catagacaaa gtcccttgcc agagggagta aaatagtggt
    57061 atactcaata aaaatcaaag agcaaactag aaagctagac gcagacagct caaaacactg
    57121 ttttgaggtt gtagataaaa ctgacaaagt caacaactat cctacggcaa gacgacgctg
    57181 acgtggtttg aagagatttt tgaagagtat taataaaggt gtacaagaag tgagattaat
    57241 tttgtatgaa aaacaaggag agaaatttat gaaagtagaa ctacagatta gtgagactta
    57301 cgaggaggaa aagctgattg tccaagcacc tcaagaaacc gaaaaagtcc agaaagtcat
    57361 cgagttcgca gaaaatctgg accaaagaga aaaaatcaaa ggaaaaatcg atgatcaggt
    57421 ctatctagtt gagattggca agattcagcg cttctatatc gagaatcgga aggttctagc
    57481 agaaaccgcg agtcagacct acagcattga tttgcgactc tatcaggttc ttaaactctt
    57541 gccaagcaat tttatccaaa tttcccaatc agaaatcatc aatatcgatt ccatctctca
    57601 cctcaagctc acgccaaacg gtctggtaga aattttcttg aaaaacgaaa gcttcaccta
    57661 ctcttcacgc cgttatctaa aaaccatcaa ggagaaatta gaactatgaa aaaacaagta
    57721 tttcacgatg cagctgccgg tgttcttatc ggcctcatcc tctccatcct cttttcactc
    57781 atttatgcac caaataccta cgcaccacta aatccctact ctctcatcgg ccaagtgatg
    57841 gatcagcatc aggttcacgg tgccctggtc ttgctctact gcacacttat ctgggcagcc
    57901 atcggtatgc tcttcaactt tggcaaccgc ttattcagcc gtgactggag catgcttcgt
    57961 gccactctga ctcatttctt ccttatgctg gctggctttg tcccactagc aactcttgct
    58021 ggttggttcc ctttccactg gattttctac ctccagctca ttatcgagtt tgcgattgtc
    58081 tatctcatca tctgggctat tctctataaa agagaggcta aaaaagtaga tcacatcaat
    58141 caactcttgg agcatagaaa ataggaacct cataataagc aaatccgaga aagaaacttc
    58201 tcggtttttc tttatcctgc tgcaccttac tatagtgaaa tgaaataaga acaggataaa
    58261 tcgatcagga cagtcaaatc gatttctaac aatgttttag aagcagaggt gtactattct
    58321 agtttcaatc cgctatatca taacagttat ttcagatctt ctcccaaatt tcaagttgaa
    58381 gttagccacc caaaagaaat tcacttggcg acttgtagtc caagcatttt ttagggtagt
    58441 tgttaatcca attttcgata aaagctactt ctttcggagt cgttttcttg gttcctttag
    58501 gtaaccatct ccgaattaat cgattatgat tttcatttga acctctctcc catgaagagt
    58561 aagcatgtgc gtagtagata tgttcctcag gaaatacctc agacaatcgt ttgaactccg
    58621 aaccattatc tgcagtaatg gacagaatac gatgctcccc taatagtaac gtaagcgcct
    58681 gattgacaga ttcagcagtt ttatttggaa ttaaccttat aatttggtgt ctgctccgcc
    58741 ggtcggttaa gactaacagg caataatttt ttatcttagt cagtaggacg gtatcaattt
    58801 cataatgacc attttccaag cgaagattaa taacgtcagg acgttcttcg atagatttac
    58861 ctgccggctt aaagttcgga ctagcttgct tcttgacacc tttccttttt ctgggataaa
    58921 gcatgtcggc cttcgtcaat cctaaatgac cattatgaaa ccagtagtag atggttgaaa
    58981 taccaacttt cacttgcttc ttgttaacca tcatttcagg cgaaaatttt tgcttatgat
    59041 agtgtaagat cttctctctg atttcctttg ttaaaattaa ctttttcacc gaccgttttc
    59101 gattgaattg gtaaacagtt tgtgcgtaat cggcagaata gacctttttg tatagccctt
    59161 ttctcacttg ttgtaaagtt gtacctcttt tgacttcagt atgaatcgtt tgaggcgcct
    59221 ttcctaacaa gcctgcaatt tcacgattgg acttattttt attcttccac cgctcaatca
    59281 agcgacggtt atctattgtc aaatgtttcc cttttggggt ataatgttct tgcatctctg
    59341 tgcctttcct tgtgtttgtg gtgaacaaca agtatagcac agaggtgttt tcttatacct
    59401 taaatcacat ttcatttgac aacaggaacc cttgaacctg ttttttcagc taaaccaagg
    59461 ctatgattag ccttggccac ctagcctaac agtttcaaac ctgttatcaa atgaaatcat
    59521 caacttactc aaacatagtg aaacatctaa ttcttgacta aggtaaggtg gctaacttca
    59581 ttatagaact ttcatttcag attttctttg taaattttct atcttttttc aaaatattct
    59641 tgcatttttc caaaattttt tgtagaatat agattacata tacagattat tctgaaaatt
    59701 caaaaaggag tatttatcat gtcgcaagct atttccttaa atcaatcaac ctgggcaagc
    59761 aagctaaaag caatgggacc tggaatccta atggcaactg ccgctgttgg aggttcccac
    59821 attgtatcct caactcaagc tggcggttct tacggttggt ctctacttct cttggtcatc
    59881 ttagccaatg tctttaaata tccatttttc cgttttggtg ctgaatacac agctgatact
    59941 ggaaagactt tggttgaagg ttatgccgaa aaaggaaaac tctatctctg gattttcttt
    60001 atcctcaatg tcttttcggc tatggtcaac acggctggtg ttgccattct gtgctcagct
    60061 atcatcgcca gtgctttccc aatgattgga cttagcatta ctcagtggtc cctcattctc
    60121 gttgcaatca tttgggctat gctactcttt ggaggctaca aacttttaga cggcatggtc
    60181 aaatggatta tgtctgcctt aaccattgcg actgttcttg cagttatcat tgcggcggtc
    60241 aagcatccag aatacagttc tgattttgtc gagaagacac cttggcaaat ggcagctctg
    60301 cccttcatcg tctccctcct aggatggatg ccggctccta ttgaaatttc agccatcaat
    60361 tcactttggt cagctgaaaa gagaaagacc gtcaacttta acacagaaga cgctctgttt
    60421 gactttaaca ctggttatat tggaacagct atcctagccg tcttctttgt ggcactggga
    60481 gcactgattc agtatcctac agggcaggcg gttgaagctg cttcagccaa atacatctct
    60541 caattcgtgg gcatgtatgc ctctgttctt ggcgaatggt cccgttactt gattaccttt
    60601 attgccttcc tctgtatctt tggaacagtt ataactgtta tcgatggcta ttctcgcgtt
    60661 aatcaggaat ctctccgact gctaatcagt caaaaagagg acaatcgtaa atctttgaac
    60721 atctggatga ccatcactgc tatcatcggt atcgtcatta tcaagttctt cgctggtcag
    60781 gtttcaacca tgctccgctt tgccatgatt ggctctttcc tgacaacacc tttctttgct
    60841 cttttgaatt acgccttggt aacgcgtgaa aacaaaaatc ttccttcttg gctcaaacac
    60901 cttgccattg cgggattgat tttcctcttt ggcttcgcca tcttctttat ctacgcactc
    60961 gcaatcggaa aagcagggta agggacaagc gcgagatgaa gataaggttt catttcaaga
    61021 gaaaattcag caaatatttc tatgataaaa agcataagaa caaggttttg aagacctgaa
    61081 cttatgcttt tttacgttct taaagactgt ttatactcaa aaaacagttg aacaacttca
    61141 accacctctt ataagaactt tatactattc gagaatctct tcaaaccacg tcagctctat
    61201 ctgcaacctc aaagctgtgc tttgagcaac ctgcgactag cttcctagtt tgctctttga
    61261 ttttcattga gtattaattc tccttttcca actcatacaa atctgcgata atagctgcga
    61321 catgtttgat atcttccagc atgcctcgca tttcaaagtc agccaataca gggaagccaa
    61381 agcgttgact gtattgcttg gctgttaggc agtattggtt attaaagtta cgatttcctg
    61441 acccaaccac accaaaacac ttactagcat tgttaccata ggcaataaaa tctcccaccg
    61501 gtgtcgtcaa aatctcaaca tctccgttat ccacgccatt cccaccttcg agataggtcg
    61561 gcaaaaaagc gacataggga tggtccattt catagaaatt tttgccttcc ttgaccaaat
    61621 ccttgatatg aatcttttga acctcaatcc ctttgtactg ggacaagaga tagtctttca
    61681 agcgcgtcac aaaactttca gtgttgccac tcaaactaat ataaactaaa gaaattgtct
    61741 tcatatgtac ctccatgatt ttatctataa tcaaaaaaca actaccaaga ttgtatcttg
    61801 atagttcttt tttgtcaata cttaggtaag ctcttctgtt tcctcttctt ctgccaaggc
    61861 tttctgttgt cgccacatct tatagaagac aagggctagg aagagaacat tgatgacgat
    61921 atagaaaatg ctaacagctt ttgaaccaat actcactgtc aaacgcatgc tctcatcttg
    61981 aaccaactgc acagcgtctt gtaaaccaac atagccataa atcgaaccaa taatagctaa
    62041 caaaacatag ccaacgtaag tatagtttgc atattgcaaa tttttacgaa caaggaagac
    62101 aatcgctacg accactaaaa tagtagatag cacaatcaaa gcaacattaa aaatagaatg
    62161 agatgcttct gctactctat aggtataatt aagctggtct tctaattgct gagcattgac
    62221 ccctgcaact tgtttctgag cagcacgaag ggcttcttta ctaggcaagg gactcacaat
    62281 tccaaacaga gacggaactg aaataagggc agacaagatt agcaaaaccc atagataaat
    62341 tggtttcttt ttcatgatag gacctcctga taatattata gcaccttttg taaaggaata
    62401 caaatcttat agtatagttt ctacctgttt tcggtaggct tttggcgatt ttccgcacaa
    62461 ttttcggaaa actttataga aatatccaag gttactgtaa ccaacagcat aacaaatatc
    62521 ttcgatgctg tcactagttg aaagcaagag ctgctgggca gccttaatac gttgtttatt
    62581 tagtaactct gcaaaggtcg aatcggtttc acgcttaatc aactgcccta gatagacagg
    62641 attgataaag agggccttac tgatatcctt gagggaaagc tctttttggt aatcacgacc
    62701 aatgacttcc agcacactga ccacattttc attcatacgg tattgatcga aaaagctgat
    62761 cagagtttcc ttgatataag aaaccaattc atcgaaggat tgaatagcat gaatggtttt
    62821 gacaatgtcc gtcatatcat cagctttgag atgttcaaat aaatggaaaa catccatgac
    62881 aaactggata aaaagctgtt tagtaatcga aacacgaggt gtattttcaa gaactacctt
    62941 ctccaagaga tttaactctt ctacgatttg attgagattt ccctgaatga taaccctata
    63001 aatcggttcg taataggcaa agagactctc agactgctgc agatttacag aaccgtaaaa
    63061 gagggttttc tcagcattca gcttccaacg ttcaaagtgt tcttgataag gagcttcaaa
    63121 aggtgtaacg actaaaccat ctaggggttg gtcagaaatg aaaatctgcc agtcttggcc
    63181 caagacatag tagggaatgg cgaaggaacc ttgtttttcc ttggatagac ctatccacca
    63241 attctcctta tcccctaaat aactaacaaa tccagcctcg tctaattctt gactaagagt
    63301 ctgacttttc ttccctctct cgccgagctg acctgcaatc ttctccagca gatttcccag
    63361 ctctacctta tcaacaggct tgaccaaata gtccaccaca ctaaggttca ttgctctttt
    63421 tacataatca aactcctgat aacctgagag caggatatag gcagcatctg gtaagatctc
    63481 tttcatctcc cgaatcatat caagccctgt tttgtctggc atattgacat cggaaatgat
    63541 gacatcgaca ggattttcct gaacatattc tagagcttca tcggcatgac tggctgttgc
    63601 gacgacctcc atatcccact tatcaaaggg aatcaaacgc ttcagacctt ctgtcaccat
    63661 gtactcatca tctactaata atactttata cattttctcc ctttctactc atcttgaatt
    63721 gtaatacgat actgaacacc ggcttgctct gcagactcta tcgtaatggc atagcggtct
    63781 ccaaaataga gcacaaaacg ctcgtgtaca ttgacaatcc cgatagactg cctttgatca
    63841 ctgtagctgg cttggtgttc aaaatatctc tgacttaatt tttctcggat atttgccaac
    63901 ttttcagccg acattcctct accattatcg accaccaaaa tttccacaaa accatcctgt
    63961 ttaagagcct tgatgctaat cacattatct gtccgcctgt ggtcaacacc atgcgcgaaa
    64021 tagttttcta ccagcggttg caaggtaaac ttgggaatct tcatattctc taactctgga
    64081 tctatcttga aaccataggc aatggacttg ggatagcgaa ccatgcagag atagctgtat
    64141 ttacggcaaa attctaattc ctgtttgagg agggtctctc tttcgtcgga aatattgtta
    64201 cgcaagagac tactgaattc ataaatgata tctgccaact catcttgact ctgcatgact
    64261 gcgtacatgc gcaagaactc cagcgtatta tacatgaagt gagggttgat ttgcgcctgc
    64321 aaggcccgca tattggcatc tttttgactg agttctaact ggtaaatatc atggatattc
    64381 ttttccaatc gatccaacat atcattggtc gtctccgcga ttaggagcaa ttcctgatcc
    64441 ttttcaagcg tatcaatgcg aagaccttct tgtccttggg caatagcttg gatggaatcc
    64501 accaaatcca ctacctgctt ttgataatta gcaaaggtct gcctcaaagt cagataaaga
    64561 atgacaataa agagaaggct caagcccaca atcaaagcag agctggtcac cgttccttgt
    64621 aaaacaaagt ttttgggaac tgccacctga acctgataac catgagaagt taagccaact
    64681 agccaatttt cactctcctt atcaactgtc tcaccaatat gaaaaatctc cgtatcaaaa
    64741 ggtgaggtca ctgttactgc catcggagta tgacctctag tattatcaat ggcatggtat
    64801 aaaacagcag gatccaagga gatgtaaatc actcctaagt cttgatctga cactggatct
    64861 gacactggaa tggcaaaact atttcctgct ggtttgaaat cctcagccct gattttttct
    64921 ccactacgtt tgtctttagt agaaacatag acttccttgt aatcttgaaa agcaatggcc
    64981 actccagtta caaaatcatt tcgaacatag aggtcatcaa cattttcata cagagagact
    65041 gatatataag gcgaagcttt ccgctctaat tgccagtaaa aatagtctgg catgctaagg
    65101 ctaaagtatt tatagattcc ctcaatacga gcttgatttt caactaaagc ctgagctatc
    65161 tgggttgact ctctatggta atattcaatt tcactcactg ttctagcagt tacacgctgg
    65221 gctactctct gggcttcctt ttcacgtgaa tcccagtcag cgtaagagag taagattgca
    65281 aaactcgcaa tgataatgat catcactgaa ctataggttc ttagaagcgt atgtagccaa
    65341 aagtgcttca ttctattttg tcgccaattt ttcatggatg atttcataga caggttccaa
    65401 catatcactg ataaagaaat gccacatccc aattcctaca aaaaatagca gggcaggcat
    65461 atagtaacca attgctacaa gtagcacagt cccaaggaga accttggcca cagctgctag
    65521 actcataaag atgccaatca aggataattt gagactattt cgataggaca aggcaaaata
    65581 aacttgtaat tttaaagata ctgtataagc caaaaagatc agggcaacta ctaggacatt
    65641 caaaagggtc gcaatcaaat gaacaatggt ctgatgaggc aattgcacca agagatacaa
    65701 accataggtc aaaactagac ccacacctaa aaagctatag aaaatcaggt tgcttgagac
    65761 aaaattttgc ttgtaaagag accaagcctc cttcaaactg tattcccgaa agctataacc
    65821 atgttctgca tataagctca tcaaggtggc actagccggc gctagaccaa ggataatccc
    65881 tcctgctaaa gttaatagcc aaaagaaggc tgtcgcaatc atccctaaaa agaaacgatt
    65941 aaagacaaag tctaaaaatc tacccatgat attcccctaa aaataactat gaaaccatta
    66001 tatcatattt caagcgtttt caaaaacttc tagtatccat ttacaatccc accaaaccat
    66061 ggtaaaatga gaattgtgaa aaaattatca ggagacaatt catgaagaaa tctatcttaa
    66121 ctacactgct ttttgcagtt ctttacttcc tctgcatggg gattggtgtc cttttgggca
    66181 atctctttga ccaaactgga aacatgtttt atgcgcctgc ctttactgcc cttgtcggcg
    66241 gtagcgtcta tatgatccta gtcgcaaaag ttccgcactt tggagccatt accactatcg
    66301 gccttgtcat tgccctcttt ttcttgggaa ctaaacacgg tgctggttcc ttccttcctg
    66361 gaattatctg tggcctccta gcagatggag tagctcattt aggaaaatac aaggacaaaa
    66421 caaagaactt cctttctttc attattttcg cctttagtac aacaggacca atcttgctta
    66481 tgtggattgc gcccaaagcc tatatggcta ctcttctggc aagaggaaaa tcccaagaat
    66541 atatcgaccg tatcatggtc gctccaaacc ctggaactgt ccttctattt atcgcaagta
    66601 ttgtcatcgg agccctagtg ggtgccttga ttggacaagc cttgagtaaa aaatttgccc
    66661 agaaaatctg atcagttaaa aagagccacg cggctctttt tatttatgac tcaatttctt
    66721 agtcaagaaa tctcccaaga attggattgc aaagataatc aaaatgataa taatggttgc
    66781 caagatggtc acatcgtgat tgtagcggtt aaatccataa gcgatggcta cgttaccgat
    66841 accaccagct ccaaccgcac cggccatagc tgtttcccca acaagggaaa tcaaggtcac
    66901 agtcgtcaca cggatcaaat ctggaagacc ttctgatagg taaacaccca cgatgtccca
    66961 gaaagtcgct ccgctcgctt gagccgcctc aatgacaccg ccatccaatt cagccaagac
    67021 aacctgcacc tgacgggcaa agaaggcaaa gactgcaaaa gaaagtggga caagggctgc
    67081 atttggcccg atacttgttt taacaatcaa gtgagaaagt ggtgacaaga ttgccaagag
    67141 gatgataaag ggaaccgcac gaaaaattga ggtaattttg tctaaaatcc agaatacgac
    67201 tttattctcc aagacaccac ctggcgctgt caagacaagg aaaagacctg ccactagccc
    67261 caagaagcct ccgatgataa aggaaagaac tgtcatataa agagttaagt agatagccgt
    67321 tccccagcct gcctgaccag cccaacccat tttatagaca tttggtaaat aggtttgaat
    67381 caatgattcc atcttactgt actcccttca atacttttag ttgtacacct gcttgacgaa
    67441 tggcttcttg ggcacctgcc aacgctgctt tttcacctga caagaccacc accaattctc
    67501 caacaggagt accatcgaga atttcgatat tcccatagag aatattagcc attacttggt
    67561 aatgcttgta caattcattc aaaagtggct cgtctgttga agctccagcg tacttgagtt
    67621 gcaccaagag actgttttca gacaagtgtt ccacgatttc ttgcttctcg attttgacca
    67681 tggcttcgtc aatacctgta gctgttgaga taaagtcttg agtcaaaggt tgtttagggt
    67741 ctgagaagat ttcaagcaca ctaccctctt caatcaaatg cccatcctgc ataaccgcca
    67801 cacggttggc aatgtctttg acaatctgca tttcatgcgt aatcaagaca acagtcaagc
    67861 ctaatttttg gttcaaatct tgcaacaagg ccaaaatctg cttggttgtc ttcggatcaa
    67921 gggcagaagt tgactcgtct gaaatcaaga tttttggatc attggccaag gcacgcgcaa
    67981 ttgccacacg ctgtttttgc cctccagata gttgtgaagg gtagttttca gcacgatctg
    68041 ccaaaccaac caagtccaac aacttagcta ctttagcctt cttttcttcc ttgctgagtc
    68101 cagagtgttt aagggcaaag gctacattct cctctgctgt cttttgactc atcaggttaa
    68161 aatgctggaa aatcatcccg atatcttgac gtttacgacg caactgctct gccgtcaagg
    68221 tgaccttacc atcaaaaatc acatcatcgt caatggtaat tttccctgca gatggttttt
    68281 gcaagaggtt aatcacccgt acaagggttg atttccctgc tccagaatat ccaacgattc
    68341 cgtagatatc cccttcttgg atgtgaatgg tcacatcctt aaccgctgtg atggttctct
    68401 tcttttggtg aaaagtcaca tcgatctgat ctaacttgat aatatctcta ctcatagctt
    68461 ctaatcagct cctctactaa ttcgatatgg gtgtaataat cagcgattcg cacattttca
    68521 tctccaccgt ggtctcggct attggcattt cctagaccga atgcaaccat tggtacctct
    68581 agggcatcaa agaccgtatg cataggtcct gtccccgctg tcgtcggcaa gactgaaacg
    68641 ccctgtggat agaatttctt ggccaactcg atcacattga gaatggctgg tgcgctcata
    68701 tcgcttcgat agctcatctc tcccaaggta tagtataatt ctaccttatc aaagccattt
    68761 ttgtctagct gtttccgaat tttttccaga acatcatgcg gttctaggcc cggaaccaga
    68821 cgaacctcta gcttggcact ggcttctgca ggtaaaatag tcttaacacc ctgaccttga
    68881 taaccagact ggattccttc gatattaagc gctggctcga aaaagaaacg ttttagaaag
    68941 gccatccgat cctcctgtaa gagaggcaac tccaatccat aaatccgact aacttcctct
    69001 gggtttcgtt gaccataagt ttctagcaag gccatttctc gttcattagg ctcttgtact
    69061 tcttcgtaca agccttcaac caagatacgg ccatccgcag cacgaagaga ctgtaaggct
    69121 tggaggagat accaaggagc tgattccaca acaccaccat aactcgagtg gatatccaca
    69181 tcagcgcttt ttaccttggc atcaaaggtc acaatcccct tattgccacc agaaatttcc
    69241 agctgttcca aggcattttt ggtcccttgt tcccagacca acaaatccgc cccacggagt
    69301 ttgtctgcat gcttttccaa atacttatct aggtctgttg aagccgattc ctccgctccc
    69361 tccatgataa agctgatatt gacaggtaaa tcatcatggt gctgcatata ttttctcaaa
    69421 gcactcaagc gagctgtgat atgacccttg tcgtcatcaa ccccacgccc atacatgaag
    69481 ccattgcgga ccgaaagcgt aaaaggatcc tctgtccaga cctgatcccc atccgctggc
    69541 acagtgtcat agtggttata gaaaatcaag gtcttggcat ctggacgcga actcttgaaa
    69601 tgtgccatga caaagggcgc tgtatagctc tcatcaatct ccacttcagc tccaacacgc
    69661 ttgaaaatct cacccagata atttgcgact tccttgagtc caacctgctg ggcaaagact
    69721 gatttcttag aaatcaaggt acgcaaaacc tcaaaataat gttggactac atgatccttt
    69781 tcaaattttt caatctgttc ttgttcgcta ggaaaaacca tattctctct acctttctat
    69841 gaacgaatag tcttctttac aatctatact ctatacaaaa gcaagaggtg gaattttctc
    69901 tcccacctcc ctgtttctta ttaccaaact ggttgatcca aaccatctga tgattcttcg
    69961 ataacttttt tcacgtcatc tgtgtggtaa gctgcgatta ctttcttgat agcatcagcc
    70021 ttaggtgatg tttcccaatc tttttttgca acaatgatgt tgtaccattg ttttgagttt
    70081 tcatcagctt gttctttgaa aagtgctttc ttgtagtcca attttgcttc tgtaacgaag
    70141 gtattgttta caacggcagc gtcaactgat gacaatgaac gagctgtttg gctagcgtcc
    70201 aattcagtga ttttcaagtt ctttggattt tctttgatgt tggcaactgt tgcaagagca
    70261 gttccagaaa catccaattt aatcaagcca gctgattgaa gcaagtaaag cgcacggctt
    70321 tcgtttgtag cgtcattcgg tacagcgatt tctccgtttg ctgggatgtc ttctacttta
    70381 gtgtacttgt tggtacttcc attcaaacct gagtaaaggc ggattggaga gatgtaagta
    70441 tctgcaatcg ctacaaggtc ttttccgttt tctttgttcc agttgttcaa gaagttatag
    70501 tgttggaaag cgttcaaatc tacttcgcca tcagcagttg ccttgtttgg ttgtgagtag
    70561 tctgtgaact ctgtaaattc caaggtaatt ccgtcttttt taaccaattc ttggattttg
    70621 tcccaacgtt tttcttcaga accgctacgg ttaacagttg cgattttgat agttgttgca
    70681 ttgtctgctt tcttttctga gtttccgcaa gctgcaagag ccaaacctgc gactgtagca
    70741 agggctgcta ggccaagcca ttttttgatt ttcatgattc tttctcctta aaaataatac
    70801 cgtactagta tctcacaatt tgtttgattt cacaaattgt tattagataa tcagatatat
    70861 agtttaaaac tatatcccta aaaactgaga aaccacccac cttactcaga atggatgatt
    70921 tcaagaaatt atttaatatc agcttctgcc ggtagataag tgtctccgaa gaattgttta
    70981 gacaattttt caagagttcc atctttataa agttctttga tgcgtttgtc tacaaatgat
    71041 ttcaactcat cttgaccttg agcaagaagt gggtaaacgt acggttgttg gtcgcttgga
    71101 agttcgataa ctttcaagtt gtccaaacct tggttcttga tcactgtttc aacaccgatt
    71161 ttatcaaaaa tcttgtagtc aaattgtcca tcgctcaaac gtaccatgat ttgttggaag
    71221 tctgccttag tatagttaag gatagttggg ttgtccgtgt gttcagcatt gtatgcttct
    71281 aactgcttag ctgatgtagt ggcttgaacg acttccgtcg attttccacc gatatcatcg
    71341 agagacttga tactagagtc atctttcttc acgacaagga cattaggatt ttgggcaatt
    71401 ggtgcggcat agaggtattt ctccgcacgt tctttagtgt agctaagatt gttgacagcc
    71461 atattgtaac ggtcagcgtc aagaccagca aagacacctg accattctgt cttttcaaac
    71521 ttgacatcat atttgtcaga atctttaaag atagcgcgaa cgacttcaat ctcgtaacca
    71581 gtcaattcgc cattttcttc atagataaat ggccttggtg atccattggt tgcaacgatg
    71641 atttctttct tgctagctgc ttctccttct ttcttagcac cccctgagca agccgcaagc
    71701 acacctgcag caacaagtcc tagggcagca agagatgagt atttaacgat ttttttcatg
    71761 tcatttcctc caaaatagaa taccttataa tcttaacaga aaaagagcat ttacgccatt
    71821 atatgatatc tatctctgtg ataagttttt ttatgggtaa tttaaaagac caaacgcaag
    71881 atggcaatca agaccactcc aaagagaact gttccgacta gattgcggta gcgaaaggct
    71941 acccaagctg ttggaaagac ggctaagaag tctagccatt taatttgagg aaggctccca
    72001 accttacctg tcactacgct tgaaagaatc aaggcaaaga taatggaaac gggcaagaac
    72061 ttcaaaaaac gctcaacgat tgcaggcaag cccttatact tgactaagat gaagggaatc
    72121 atacggagaa tccaagtcac caagccagag aaaataactg ctaataaaag atacttactg
    72181 accatctaaa accaccccca tgctacaacc aagtagcgtc gcaaacagaa cagctagtga
    72241 ctgagacacc actgtcaaga gcaaaaagaa ggacaccgca acaactgcta ggataatgag
    72301 cagattgcgg acaggaatcc gtctttgcat catctgaaat tgcgaagcaa aaataccaat
    72361 aaacatccca accagggcaa aatccaagcc aaagatttct ggatttggta gcaggccacc
    72421 cagatccgtt ccgactactg tccccacaaa ccaagccaca tagctgttaa gattgtttcc
    72481 gtgcatccac ataggattta ccttgtctgt atgggccaat tcacccatca aaacgccata
    72541 ggtctcatct gtcaagatac tagacatacc gatattgtac caaagactgg tatgacggaa
    72601 ataagtcgat gcgtgtaaac tcaacaaaaa gagacgcaag ttgattagaa aaaccgtcat
    72661 agcaatagct gccacaggag cttgaaccac aatcagtgcc aacatggcaa actgggcact
    72721 cccagcataa acaaagagac tcatcaagcc catctcaaca ggtgtcacat agggcgcacc
    72781 gatagtccca caggccaggc cgatactgac atagccaaga gccgttggca tggctgcctg
    72841 cgccccctcc taaaatcctt tttctttcat ctttctcctc atattgtctt aataatactc
    72901 aatgaaaatc aaagagcaaa ctaggaaact agccgcaggt tgctcaaaac accgttttga
    72961 ggttgtggat agaactgacg aagtcagtaa ccatacctac ggcaaggtga agctgacgtg
    73021 gtttgaagag agtttcgaag agtataagta ggctgaaaag aatccagtca cagcatggac
    73081 tattatatag cagattgaaa taagatgaga acaaatcgat tgggaaagta aaattaattt
    73141 ctataaatgt tttagcaatt gtttcatact attttagatt cagtttacta taacacattc
    73201 agaaaagaga aaaagtctgt tgattttgac catcataaaa agactggcaa tccagtctca
    73261 aacatatatt atagaaattc tccactaaat actttcacga atattcagaa gcataacaaa
    73321 ggcaactaga agaaatagca ataaaacaaa gctaactgcc agagttccaa agctagtagc
    73381 aatggttacc aaagctattg taaataagct aggtaaaaca accgtaatgg caccgataga
    73441 ggattgaact gctcccattg actcctcagg tatttgttta aaaacgagtt cttgcaatct
    73501 aggagagaga acacctgcga aaaaggcatc caaggtacta aagatgagaa tccagtcaaa
    73561 acgaactgtg gcaaatccta ctagaagaag caactgggtg acaagtgagg catagagagc
    73621 tgtttttata gaaatcgtat gtttcagata gccacttaca aggcttccga caatcagggc
    73681 tgacagttca aaagtggata gcaaggcaag agattgacct gtttgtaaat tcaaaaaggg
    73741 ttgattcctc aaaaatagag tagagacagg aactgtaaca tttatcactg cttgactagt
    73801 agagataata aacaaaacca agagcacctt attcatattc catatcaatt tcgatgattg
    73861 gagcaaatgc tggcaaaagg attttacaga gagtccttct tgatagttaa tcgttttttc
    73921 tactttcaag aggtcagttt ttatgaagag gatacctaaa aatgcgatta aaaaggtaag
    73981 agcgttcagc aaggaaataa actggatgga tagaatacct aataagactc ctcctagaat
    74041 attactgatt gttttcacta aactaacagt tgactgttta aatccaatag cttctgccag
    74101 atggtcttgc ccaataattc taatgaaaat cggagtgagc atggcgcctg aaaaataact
    74161 caacgtgtca gacaagaggt taatcagaca aataaatgct actaataaca aggaaaagga
    74221 ctgccctgaa agtgataaag acactataga gtaaagcaaa aattttgcaa aactaatgac
    74281 tgtgtatttc aagacacgat gatgttgaaa atccgccaaa actcccagaa agatttgtag
    74341 aacttggggc agggtttctg aaatcgtgat gagtaaaatc gccaaagggg caaaagatgc
    74401 atctgccaca taattcagga aggccagata aaaaatcgta tccccaagcg ttgaaatcca
    74461 ctggttgata gttaattgcc taaaatctct attttgaaga aatactttca tcacaactcc
    74521 ttcttaagtt caaatgggaa tctttcccca aggatagacc gcgatactac taacaaccaa
    74581 aattacagta acatcaaaag ctgaccaatg ccattgtaga ctatatgcag tccaataggc
    74641 caataaattg actttgtcat tctaaataag actgcaaata taagacctcc acccatatag
    74701 aagacaaagt ctgtcaagac ccaaccgtga ttactaatgt gcgagacccc aaataaaaca
    74761 gcggaaccaa gtacatctag cccccatttc tttccttttt ccagagcagt catcactaat
    74821 ccacgataaa tcatgtcttc aaaaatggga cctgcaatca caggataaaa aaaatacatc
    74881 aaaaatgccg tagctcctgt aaaagtagga gcagcatgtt gataagaaat ttcatttcga
    74941 gtaggtggga aaagaaaaaa ggtgacaaaa ttccaagcaa caaaagcaag cagagctagg
    75001 aaggaataga aaagatagga tcctttaaac tttctactat tgattttctg ccatttcccc
    75061 gaccaaatca tagcaataag agcaaataaa accacaagaa aattcaacat catatccgac
    75121 agataatagg caaagtcaga tagcccagca acaaggtcgc tgcgtaaaac taaaacactg
    75181 aacttctggt cagcaataac tagtagaaaa actataataa agtagcggtg tgagattatc
    75241 tttttcattc tatttcctcc tatacatatg aaataaagac agcccctacc caagaaaagg
    75301 caagggcttt ggatattaat aacgacggcg gtcagaatca aagtcaggtc tatcgttaaa
    75361 atttttcttc cagaaattag tgattgacca agacgttcct aaacctcccc aactaccacc
    75421 tgggataacg gcattatacc caagttcccc tccataaact gtctccaact cagcttctgt
    75481 caattccatt gtttctgcaa attgtaaatt taacatcttt tacactcctt caattatctt
    75541 catttgtaaa ccacttctgc gacctaggat ttgcttcaaa tgttttacaa ggacagtata
    75601 acacggaaat tggcttattt tagaaaatcg catatttgat attttttctt atagaaattt
    75661 cagatttgcg attttggtag atttgattat ttccctggta taataaagtt attactaatg
    75721 aggagggaag taatatgaag aaacaagttt taacattatt gacgatcgtt gctgatatta
    75781 ttatcttttt cccatttcta actaatctat aagttcttta tattgctgaa aacgcaattc
    75841 aaaaagggat gttaattgtg gattttctaa tacctgcaga gattgggtaa agcgttcaat
    75901 ctctttttga ttgcttccct ttgtttgaag aaagacactc atcttcttta aaaattgcca
    75961 cgatactttt tcaaaaacat cgtacggacg caacatgctc tccaactcgg cttcgaagat
    76021 tgggatgtat aagaaaagtt ttcgctccat gagttctgat aagatattta agagtccttg
    76081 cttcatatac aatcgattgt gtactaactc tttaaattcc ttggattttt cgagtaagga
    76141 ggttgataaa aagatcagat cttgattgct caagaagggc atagtattgc aaaaaagata
    76201 gagttcaaac caggtccaag actcaatagc gtagaggtag gtagtcaaaa actcgctatc
    76261 ctcctctgtt agcgggtatc ttttatctaa ggaatggagt gcatttttaa tcacaatggc
    76321 attcaaacga cgataggtct gcgccatctg ttcttgatcg acttcctcca atagctgctc
    76381 taaagcagct atatcctgat gggcaaagcg atccacaacc tttcgaccga ttcgcatatg
    76441 tggagattct tgatagttgt tgagcttgtg cccaaactca tcaaaattca tattgatccc
    76501 ttggatggct aggatcagct tgtctgcaga cagcatagac tgtcctagtt caaacttgga
    76561 caactgagag gctgttagtc cagcacaagc cacatctgac tgcttgagct ttctagccaa
    76621 gcgcaattcc ttgtaaaatt cccccagttc cattttttca atcatcctac cacctcctag
    76681 cttttgcata ttatatcatt atttgtgttc atttgtcaaa acattctgac actttggtga
    76741 ttgaaaaagc cagccttaag ctgactctaa aaggaccgag ccttgtacaa tacagaactc
    76801 aatcctcgtt ctaaatagaa tgtctaactt ttttgggcag tacacgagct tggggaacag
    76861 ccactggaac gatgaggtgt gagctcaaaa tatcctccag ttatgttttt cctaatagta
    76921 taccggaaga gtgaaaggat tttataatgg agcagttaca aagaacctac tttctattaa
    76981 acagtatact atgaaaatgt gaaaatttaa catttttttg tacaaatttt ataaattatt
    77041 gcctttttaa tatcaatagt taatctctta tccagatccc ccttgtgtaa actttatctt
    77101 tataagcttc aaggccccta tcccatctat ttgcaacaat tagatcactt tgttttgtaa
    77161 atagttcaaa attcttttca aaaattacgt tatctatact aacgtttaaa tttggttcat
    77221 atactaaaat ttttataccg acaatcaata gttcattaat tatacttaaa atagctgact
    77281 ctttgtaatt atctgaatta tatttcatcc ccaatttata tattcctact atctttggct
    77341 ttcgttccaa tatttgttta actatgaact gttttctatt tgtgtttgaa atatcaatcg
    77401 cttctatcac tggggcattt atttctataa attctttttt taattgttta gtatctttgg
    77461 gaagacaata tcctccaaat ccaaaagaag gattattata aaattttcca attcttggat
    77521 ctaaacaaac accttttatt acaacttcag catttaaact tctcctctca gcaaaagaat
    77581 ctagttcatt aaaaaaagca acacggagag ctaagaatgt gttagaaaaa agcttaattg
    77641 cttctgcttc agtaggagaa actaacataa catttttaat attggcagta ctatgagtac
    77701 taatcgaaag gaacaactct gcaatttttc ttccttcaac tgtctcatct ccaacaacta
    77761 tgcgacttgg atataaatta tcatatatag aacaaccttc tctcaaaaat tcagggacaa
    77821 aaatgatatt ttttgtatca aacagccttt ttaatttgtt tgaaaagccg aacggaactg
    77881 ttaactttaa aataatcttt ccattaggtt ttaccctcag aatcttcgat accgtttgtt
    77941 cgatttcata tgtattaaaa ctaccaattt tctcatcata atctgtc
//
LOCUS       DAVLDI010000002        69749 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLDI010000002 DAVLDI010000000
VERSION     DAVLDI010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 69749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69749
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.002"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(1..249)
                     /locus_tag="VXD01_000099"
                     /pseudo
     CDS             complement(1..249)
                     /locus_tag="VXD01_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            956..2431
                     /locus_tag="VXD01_000100"
     CDS             956..2431
                     /locus_tag="VXD01_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV0600568.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(2397..3112)
                     /locus_tag="VXD01_000101"
                     /pseudo
     CDS             complement(2397..3112)
                     /locus_tag="VXD01_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            3368..4228
                     /gene="speE"
                     /locus_tag="VXD01_000102"
     CDS             3368..4228
                     /gene="speE"
                     /locus_tag="VXD01_000102"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV0600569.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            4225..5484
                     /locus_tag="VXD01_000103"
     CDS             4225..5484
                     /locus_tag="VXD01_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV0600570.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            5484..6611
                     /gene="nspC"
                     /locus_tag="VXD01_000104"
     CDS             5484..6611
                     /gene="nspC"
                     /locus_tag="VXD01_000104"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV0600571.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            6608..7693
                     /gene="aguA"
                     /locus_tag="VXD01_000105"
     CDS             6608..7693
                     /gene="aguA"
                     /locus_tag="VXD01_000105"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV0600572.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            7703..8578
                     /gene="aguB"
                     /locus_tag="VXD01_000106"
     CDS             7703..8578
                     /gene="aguB"
                     /locus_tag="VXD01_000106"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV0600573.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(8758..9567)
                     /locus_tag="VXD01_000107"
     CDS             complement(8758..9567)
                     /locus_tag="VXD01_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0600574.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            9839..10060
                     /locus_tag="VXD01_000108"
     CDS             9839..10060
                     /locus_tag="VXD01_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600575.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKEPNGYYPWQMEPVLTMP
                     VHGFCPRGTDDLVYIVGGNHLCKGSAARF"
     gene            10114..10785
                     /locus_tag="VXD01_000109"
     CDS             10114..10785
                     /locus_tag="VXD01_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0600576.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLLESGVLLSAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVIMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(10837..11034)
                     /locus_tag="VXD01_000110"
     CDS             complement(10837..11034)
                     /locus_tag="VXD01_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0600577.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            11027..11935
                     /locus_tag="VXD01_000111"
     CDS             11027..11935
                     /locus_tag="VXD01_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0600578.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11932..12393
                     /locus_tag="VXD01_000112"
     CDS             11932..12393
                     /locus_tag="VXD01_000112"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV0600579.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            12383..13270
                     /locus_tag="VXD01_000113"
     CDS             12383..13270
                     /locus_tag="VXD01_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0600580.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            13273..15168
                     /gene="cbpE"
                     /locus_tag="VXD01_000114"
                     /gene_synonym="pce"
     CDS             13273..15168
                     /gene="cbpE"
                     /locus_tag="VXD01_000114"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV0600581.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHLDTKNSNTKNFIKNLSPEIIVQ
                     TSSSPIGSYDSGQEINREYISWLESMGIQHINAASKDYDATVFDIRQDGLINISTSYK
                     PIPSFQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNN
                     RWFYLTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQY
                     KGQWYYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWH
                     KKANDWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVS
                     IEKSATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSV
                     NKSESEQ"
     gene            15248..16378
                     /locus_tag="VXD01_000115"
     CDS             15248..16378
                     /locus_tag="VXD01_000115"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV0600582.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDEVKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDILRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            16388..17650
                     /locus_tag="VXD01_000116"
     CDS             16388..17650
                     /locus_tag="VXD01_000116"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV0600583.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSHESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            17654..18451
                     /gene="proC"
                     /locus_tag="VXD01_000117"
     CDS             17654..18451
                     /gene="proC"
                     /locus_tag="VXD01_000117"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV0600584.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLILEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            18671..19309
                     /locus_tag="VXD01_000118"
     CDS             18671..19309
                     /locus_tag="VXD01_000118"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV0600585.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEVKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            19306..20196
                     /locus_tag="VXD01_000119"
     CDS             19306..20196
                     /locus_tag="VXD01_000119"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV0600586.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            20236..20553
                     /gene="yabA"
                     /locus_tag="VXD01_000120"
     CDS             20236..20553
                     /gene="yabA"
                     /locus_tag="VXD01_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV0600587.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            20556..21434
                     /gene="rsmI"
                     /locus_tag="VXD01_000121"
     CDS             20556..21434
                     /gene="rsmI"
                     /locus_tag="VXD01_000121"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV0600588.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASKGVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEENQEND"
     gene            21569..22903
                     /gene="trmFO"
                     /locus_tag="VXD01_000122"
     CDS             21569..22903
                     /gene="trmFO"
                     /locus_tag="VXD01_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV0600589.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            22987..23724
                     /locus_tag="VXD01_000123"
     CDS             22987..23724
                     /locus_tag="VXD01_000123"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV0600590.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            23733..24290
                     /gene="frr"
                     /locus_tag="VXD01_000124"
     CDS             23733..24290
                     /gene="frr"
                     /locus_tag="VXD01_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV0600591.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            24350..25204
                     /gene="cvfB"
                     /locus_tag="VXD01_000125"
     CDS             24350..25204
                     /gene="cvfB"
                     /locus_tag="VXD01_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV0600592.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            25213..25428
                     /locus_tag="VXD01_000126"
     CDS             25213..25428
                     /locus_tag="VXD01_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV0600593.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            25514..26518
                     /locus_tag="VXD01_000127"
     CDS             25514..26518
                     /locus_tag="VXD01_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV0600594.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIYQIDFVHFSAKDVVRHPVVAQIIRAYEPAPVKKEESEELESQPLSEG
                     "
     gene            26626..27195
                     /locus_tag="VXD01_000128"
     CDS             26626..27195
                     /locus_tag="VXD01_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0600595.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKDRIVTRVHYVLTKEDYFANK"
     gene            27263..27913
                     /locus_tag="VXD01_000129"
     CDS             27263..27913
                     /locus_tag="VXD01_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV0600596.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            27897..30137
                     /locus_tag="VXD01_000130"
     CDS             27897..30137
                     /locus_tag="VXD01_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV0600597.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLIKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQTTQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            30316..30504
                     /locus_tag="VXD01_000131"
     CDS             30316..30504
                     /locus_tag="VXD01_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600598.1"
                     /translation="MTATKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            30536..31123
                     /locus_tag="VXD01_000132"
     CDS             30536..31123
                     /locus_tag="VXD01_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0600599.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            31127..32308
                     /locus_tag="VXD01_000133"
     CDS             31127..32308
                     /locus_tag="VXD01_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600600.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVNLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFK
                     V"
     misc_feature    32468..32599
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            32615..33145
                     /gene="infC"
                     /locus_tag="VXD01_000134"
     CDS             32615..33145
                     /gene="infC"
                     /locus_tag="VXD01_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV0600601.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            33178..33378
                     /gene="rpmI"
                     /locus_tag="VXD01_000135"
     CDS             33178..33378
                     /gene="rpmI"
                     /locus_tag="VXD01_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV0600602.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            33430..33789
                     /gene="rplT"
                     /locus_tag="VXD01_000136"
     CDS             33430..33789
                     /gene="rplT"
                     /locus_tag="VXD01_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV0600603.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            33847..34227
                     /locus_tag="VXD01_000137"
     CDS             33847..34227
                     /locus_tag="VXD01_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0600604.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            34477..35277
                     /locus_tag="VXD01_000138"
     CDS             34477..35277
                     /locus_tag="VXD01_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV0600605.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            35240..36226
                     /locus_tag="VXD01_000139"
     CDS             35240..36226
                     /locus_tag="VXD01_000139"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV0600606.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            36268..38433
                     /gene="lytB"
                     /locus_tag="VXD01_000140"
     CDS             36268..38433
                     /gene="lytB"
                     /locus_tag="VXD01_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV0600607.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWIFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWIYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFY
                     LKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNKNAA
                     YYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQ
                     ALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLYFDGFKLE
                     NPFLFKDLTEDTNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHS
                     ALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGR
                     TFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(38494..40149)
                     /gene="pavA"
                     /locus_tag="VXD01_000141"
     CDS             complement(38494..40149)
                     /gene="pavA"
                     /locus_tag="VXD01_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV0600608.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            40254..40751
                     /gene="ybeY"
                     /locus_tag="VXD01_000142"
     CDS             40254..40751
                     /gene="ybeY"
                     /locus_tag="VXD01_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV0600609.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            40732..41127
                     /locus_tag="VXD01_000143"
     CDS             40732..41127
                     /locus_tag="VXD01_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV0600610.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            41144..42043
                     /gene="era"
                     /locus_tag="VXD01_000144"
     CDS             41144..42043
                     /gene="era"
                     /locus_tag="VXD01_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV0600611.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEKEY"
     gene            42091..42915
                     /gene="mutM"
                     /locus_tag="VXD01_000145"
     CDS             42091..42915
                     /gene="mutM"
                     /locus_tag="VXD01_000145"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV0600612.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            42915..43520
                     /locus_tag="VXD01_000146"
     CDS             42915..43520
                     /locus_tag="VXD01_000146"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV0600613.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            43507..44706
                     /locus_tag="VXD01_000147"
     CDS             43507..44706
                     /locus_tag="VXD01_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV0600614.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSIMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            44706..44855
                     /gene="rpmG"
                     /locus_tag="VXD01_000148"
     CDS             44706..44855
                     /gene="rpmG"
                     /locus_tag="VXD01_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0600615.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            44895..45128
                     /gene="secG"
                     /locus_tag="VXD01_000149"
     CDS             44895..45128
                     /gene="secG"
                     /locus_tag="VXD01_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV0600616.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            45230..47584
                     /gene="rnr"
                     /locus_tag="VXD01_000150"
     CDS             45230..47584
                     /gene="rnr"
                     /locus_tag="VXD01_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV0600617.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERIIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLCIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            47547..48014
                     /gene="smpB"
                     /locus_tag="VXD01_000151"
     CDS             47547..48014
                     /gene="smpB"
                     /locus_tag="VXD01_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV0600618.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            48030..48890
                     /gene="tehB"
                     /locus_tag="VXD01_000152"
     CDS             48030..48890
                     /gene="tehB"
                     /locus_tag="VXD01_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV0600619.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            48963..49916
                     /gene="coiA"
                     /locus_tag="VXD01_000153"
     CDS             48963..49916
                     /gene="coiA"
                     /locus_tag="VXD01_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV0600620.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQYFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            49935..51737
                     /gene="pepF"
                     /locus_tag="VXD01_000154"
     CDS             49935..51737
                     /gene="pepF"
                     /locus_tag="VXD01_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0600621.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKIGLA"
     gene            51739..52452
                     /locus_tag="VXD01_000155"
     CDS             51739..52452
                     /locus_tag="VXD01_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV0600622.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGSLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            52519..53460
                     /gene="prsA"
                     /locus_tag="VXD01_000156"
     CDS             52519..53460
                     /gene="prsA"
                     /locus_tag="VXD01_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV0600623.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKSNPSVQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(53579..53908)
                     /locus_tag="VXD01_000157"
                     /pseudo
     CDS             complement(53579..53908)
                     /locus_tag="VXD01_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            54331..54426
                     /locus_tag="VXD01_000158"
                     /pseudo
     CDS             54331..54426
                     /locus_tag="VXD01_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(54679..55299)
                     /locus_tag="VXD01_000159"
     CDS             complement(54679..55299)
                     /locus_tag="VXD01_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0600624.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPGSIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(55299..55781)
                     /locus_tag="VXD01_000160"
     CDS             complement(55299..55781)
                     /locus_tag="VXD01_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV0600625.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYHIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(55781..56623)
                     /locus_tag="VXD01_000161"
     CDS             complement(55781..56623)
                     /locus_tag="VXD01_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV0600626.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(56718..57518)
                     /locus_tag="VXD01_000162"
     CDS             complement(56718..57518)
                     /locus_tag="VXD01_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV0600627.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSAQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            57662..59041
                     /gene="glmU"
                     /locus_tag="VXD01_000163"
     CDS             57662..59041
                     /gene="glmU"
                     /locus_tag="VXD01_000163"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV0600628.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            59051..59596
                     /locus_tag="VXD01_000164"
     CDS             59051..59596
                     /locus_tag="VXD01_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0600629.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELKKK"
     gene            59608..59922
                     /locus_tag="VXD01_000165"
     CDS             59608..59922
                     /locus_tag="VXD01_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV0600630.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKNHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            59939..60631
                     /locus_tag="VXD01_000166"
     CDS             59939..60631
                     /locus_tag="VXD01_000166"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV0600631.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVCGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            60708..61199
                     /gene="rocS"
                     /locus_tag="VXD01_000167"
     CDS             60708..61199
                     /gene="rocS"
                     /locus_tag="VXD01_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV0600632.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            61297..61887
                     /locus_tag="VXD01_000168"
     CDS             61297..61887
                     /locus_tag="VXD01_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV0600633.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIDYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            61896..63659
                     /locus_tag="VXD01_000169"
     CDS             61896..63659
                     /locus_tag="VXD01_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV0600634.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVITCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQENPEYTDLLLKKALEFFEF"
     gene            63873..64388
                     /locus_tag="VXD01_000170"
                     /pseudo
     CDS             63873..64388
                     /locus_tag="VXD01_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            64558..64758
                     /locus_tag="VXD01_000171"
     CDS             64558..64758
                     /locus_tag="VXD01_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600635.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKVPEDSALTE"
     gene            64783..65199
                     /locus_tag="VXD01_000172"
     CDS             64783..65199
                     /locus_tag="VXD01_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600636.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGLAETETKLVEELKAILDKLK"
     gene            65430..66137
                     /gene="ccdA2"
                     /locus_tag="VXD01_000173"
     CDS             65430..66137
                     /gene="ccdA2"
                     /locus_tag="VXD01_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0600637.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            66148..66705
                     /gene="sdbB"
                     /locus_tag="VXD01_000174"
     CDS             66148..66705
                     /gene="sdbB"
                     /locus_tag="VXD01_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV0600638.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            67079..68470
                     /locus_tag="VXD01_000175"
     CDS             67079..68470
                     /locus_tag="VXD01_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV0600639.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            68613..69530
                     /gene="adcAII"
                     /locus_tag="VXD01_000176"
     CDS             68613..69530
                     /gene="adcAII"
                     /locus_tag="VXD01_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV0600640.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSILAEELK"
     gene            69538..>69749
                     /locus_tag="VXD01_000177"
     CDS             69538..>69749
                     /locus_tag="VXD01_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0600641.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIV"
BASE COUNT        20990 a        12726 c        15611 g        20422 t
ORIGIN      
        1 gaccgagcgc ttgcgattgt tttcataaga ctgttgagca tagtcggcag aataaacctc
       61 tttgaagcgc ccttttccaa gacattgtcg gactgtccca cgcttgattt cagtgtggat
      121 agtttaagga gcttttccaa gtagagaggc aatttctcta tttgatttcc cttctttttt
      181 ccatctttcg attaagcgac ggctatcgat tgtcaaatgt ttggcttttg tagtataatt
      241 ttcttgcatc tctgtgcctt tcttgtgttt gtggttgaac aacaagtata acacagaggt
      301 gttttcttat gcctacaaga gctatcagct agttgaacca tctaattttt aggagggctg
      361 ggtggctaac ttcattatag aactttcatt tacgaacata tagtaaaatg aaacaagaac
      421 agaacaaatc gatcaggaca gtaaaatcta tttctaataa tgttttagaa gcagaagtgt
      481 actattctag tttcaatcta ttatattttt gttttttatc aaaaaatact ttacaagttc
      541 ttaaaaacat gatatagtaa taaagcttag aaaatgagat gatgttttct agcaaatata
      601 aacccgagta aaaaatgcct acggacaggc agggttgaat gccgaagcgt ggttgaaaag
      661 ccacattatt gatagggtta aaagcctact tttataagtt gatgttagga cacttgtcct
      721 aattcataaa tttttagtgt ggtgaaagca cacgtcatct tgtgaaacga tcaataaagt
      781 acgtaatatt tgctactaga gagttaggaa acatcgggaa cagacatact caacagaaac
      841 caaaataaac acgtcagaag attgcagagc aggtgaaaac ctgctctttt ttcatgagtc
      901 aacctttagt tccttagttt tcataaggtc ctaaaaatat tgaaaggagt atgttttgaa
      961 agagttagat caaaaccaag ccccaattta tgaggccttg gtgaagttac gcaagaaaag
     1021 gattgttccc tttgatgttc caggtcacaa gcgtggacgg ggaaatccag aacttgtcga
     1081 actcttagga gaaaaatgtg taggcattga tgtcaattcg atgaaaccct tggataattt
     1141 aggccatcct atttcgatta ttcgtgatgc agaggagctg gctgcagatg cttttggagc
     1201 tagccatgcc tttctaatga ttggtggaac aacttcatcg gtgcagacta tgattctggc
     1261 aacctgcaag gcaggagata agattattct gccacgaaat gtccataaat ctgctatcaa
     1321 tgcgttggtt ctatgtggtg ccattcccat ctatatcgag atgagtgtag atcctaagat
     1381 tggtatcgct ttaggtcttg aaaatgaccg agtagcacag gccataaagg accatccaga
     1441 tgctaaggct atcctaatca acaatcctac ttactacggc atctgttcag acctaaaggg
     1501 gttgacagaa atggctcatg aagctggcat gatggtttta gtagatgaag cccatggagc
     1561 gcatttgcat ttcactggta aacttccaat ttctgctatg gatgcaggag ctgatatggc
     1621 agcagtttcc atgcataagt ctggtgggag tttgacacaa agttcgcttc ttttaatcgg
     1681 ggagcagatg aatcccgaat acgttcgtca gattataaac ctgacccagt ctacatctgc
     1741 ctcttactta ttgatggcta gtttggatat ttcacgtcgc aacttggccc ttcgtggtaa
     1801 agagtcgttt gaggaagtca ttgagctatc cgagtacgct cgtcatgaaa tcaatgccat
     1861 tggcggttac tatgcttact caaaagagtt aatagatggt gtgtcggtct gtgattttga
     1921 tgtaaccaag ttgtcagttt acactcaggg aataggctta acaggtatcg aggtttatga
     1981 cctcttgcga gacgaatacg acattcagat cgagtttggt gatatcggca atatcttggc
     2041 ctatatttcc atcggcgacc gcatccaaga catcgagcgc ttggttggtg ctctggctga
     2101 tattaagaga ctctattcac gagatgggaa ggacttaata gctggagaat atattcagcc
     2161 cgagttggtg ctgtctccac aagaagcctt ctattcagag agaaaaagtt tgaccttaga
     2221 tgagtctgtt ggacaggtct gtggagaatt tgtcatgtgc tatcctccag ggattcctat
     2281 cttggctcct ggtgaacgca ttacacgaga aattgtagac tatatccaat tcgccaagga
     2341 acgtggttgc tccctccaag ggacggaaga tccagaggtc aatcatatca acgttattaa
     2401 gagaaagaca aactataaga aaagtcaata gttttatcta aactatttct tatttcaatt
     2461 tgatgatttg gcgatgattt tagagcacgg caaaaagccc ttgaattaga agcggtcaat
     2521 cgcttaattt ctatcagctt atcaaatcct gcctcaatcc ttttctgagg attagggtag
     2581 cgtgtcaaga gttggtaggt atattctgaa tgctttccaa cgattttatc caactcagga
     2641 aagatgatat caagacaacg agtgtattgt actttccaat cagactgttt ttcttgagac
     2701 gatgaatatg tctagccagt atttttagtt ctacttgccg attatcgtgt tgaaattgtt
     2761 cacgattggg gtcagaaaga agtttaagag cgatgccatg agcgtctttc ttatccgttt
     2821 tagtcttgcg aagtgataat gatttggcaa attccttgat gagcaaagga ttgcaggtgt
     2881 aaactttata tccttgttca tgcaggaagt tcagtagatt aaaggcataa tgtccggtat
     2941 tttcaagagc gatgagacag tcttggttga gttgtcgaag agacagatct aagagttcaa
     3001 aaccagcttt attatttgaa aaagtgagtg gtttaagaac agtttttcct ggaacattca
     3061 aggctgtaac atcgtgttta tttttagcga catcaatgcc cacataaagc atgggagtac
     3121 ctccagatgt agtatttcaa gtctacttgg ttatccacga attttttgcc ttgttacctt
     3181 agacgagata aaacgtctat gcgttatcaa actcattacc aattgaaaca aaaaactgtg
     3241 gttagagcct ttcggaaatc gtcaagcgat tggagggaat aaactaatcc acagtggctt
     3301 attccaagta taccacttgg gctttggcag tagctaactg cgctaaatat aatataagga
     3361 gaaatagatg gatttatggt tttctgaagt tcatactcca gatgtcaaat tgtctctgag
     3421 aacagccaag caactttacg ctggaaaaag tgaatggcag gatatcgaag tcttggatac
     3481 gccagctttt gggaaaatac tgattttaaa tggccatgtc ttgttctcag atgcggatga
     3541 tttcgtctac aatgaaatga ccgttcacgt tcccatggct gtccacccaa atccaaagaa
     3601 agtattggtt attgggggtg gtgacggcgg tgttgcccaa gtattaacac tctatcctga
     3661 actggaacaa atcgatatcg tggaaccgga tgagatgttg gtcgaggtct gtcgtgagta
     3721 tttcccagac tttgctgcag ggctagatga tcctcgtgtt accatttact accaaaatgg
     3781 gctacgcttt ttgcgaaact gcgaagatga ttacgatatt atcatcaacg atgcgacaga
     3841 tccatttggc catacggaag gactctttac caaggaattc tacggcaata gttatcgagc
     3901 tctgaaggaa gacggcatca tgatttacca gcatgggagt cccttctttg acgaggatga
     3961 gtcggcctgc cgaagcatgc accgcaaggt caatcaatcc tttccaatca gtcgggttta
     4021 tcaggcccat attccaacta gcccagctgg ctattggttg tttggatttg catcgaaaaa
     4081 ataccaccct gtcaaagatt ttgacaagga aggttggaaa aaacgccagc ttttcacaga
     4141 atactacact gcaaacttac acgtgggatc ctttatgttg cccaagtatg ttgaggacat
     4201 tttagaagaa gaggaaggaa aaaaatgagt cgtttactag ttattggttg tgggggcgtt
     4261 gcccaagttg ctatttcaaa gatttgtcaa gatagcgaaa catttacaga gattatgatt
     4321 gctagccgta ccaagtcaaa atgcgatgac ttgaaagcga agctagaagg caaaacaagt
     4381 actaaaattg aaactgcagc acttgatgct gacaaggttg aagaagtgat tgccctgatt
     4441 gaaagctaca aaccagaagc tgttttgaat gtagctctgc cttatcaaga tttaaccatt
     4501 atggatgctt gtttggcaac aggtgttcac tatatcgata cagccaacta cgaagcagaa
     4561 gacacagaag accctgagtg gcgtgctatc tacgaaaaac gttgtaagga acttggtttt
     4621 acagcctact ttgactactc atggcagtgg gcttatcaag agaaattcaa agaagcaggc
     4681 ttgactgctc ttcttggttc tggctttgac ccaggtgtaa ctagtgtctt ttcagcttat
     4741 gccctcaaac actattttga tgaaatccat tatatcgaca ttttagactg taatggcggt
     4801 gaccacggtt atccatttgc aaccaacttt aatccagaaa ttaatctccg tgaggtttct
     4861 gcgccaggtt cttactggga agatgggaaa tgggtcgaag tcgaagctat gtctatcaag
     4921 cgtgagtatg atttccctca agttggacaa aaagatatgt atctccttca ccatgaagaa
     4981 atcgaatcat tggccaagaa cattccaggt gtcaaacgca ttcgtttctt tatgactttt
     5041 ggtcaatctt acttgacgca catgaaatgt cttgaaaatg ttggactcct tcgtacggat
     5101 accattaact ttaacggcca agaaattgtt ccaattcaat ttttgaaagc cttgcttcca
     5161 gatcctgcta gccttggccc acgtactgta ggtaaaacca atattggatg tatctttaca
     5221 ggtgtcaaag atggcgttga aaagactatc tacatctaca atgtttgcga ccatcaagag
     5281 tgctatgcag aagtcgggtc acaagcaatt tcatacacga caggcgttcc agccatgatt
     5341 gggacaaaat tagtcatgaa cggaacttgg aaacaagctg gagtgtataa ccttgaggag
     5401 ttagatccag atccattcat ggaagctttg aatgagtatg gtttgccatg ggttgtggtt
     5461 gaaaatccac aaatggtgga ctaatgaagt tagaacaagt accaacacca gcctatgtta
     5521 ttgacttggc caagttagaa gctaattgcc gcattctaca atatgtacaa gaagaggtcg
     5581 gttgcaaggt cttgcttgcc cagaaggcat attccctcta caaaacttat cccttgatta
     5641 gccagtatct atcaggtacg acagctagtg gactctatga ggccaaattg gcaagggaag
     5701 aatttcctgg tgaagtccat gtatttgcgc ctgctttcaa ggatgcagac ttggaggaat
     5761 tgcttgggat aacagaccat atcgtcttta actcagagag acagttgcgt aagcatgggg
     5821 ctcgttgtcg agaggctggt gtcagtgttg gtttgcgcct caaccctcag tgttcaactc
     5881 aaggagatca cgcgctctat gacccttgtg caccaggttc tcgctttgga gttactatag
     5941 acaagattcc gagtgatttg ctagatttgg ttgacggact tcattttcat accctttgcg
     6001 agcagggagc agatgattta caaacaactt tgaaagcagt agaagaacag tttggtccct
     6061 acttacatga ggtaaaatgg ctcaatatgg gtggtggtca tcatattaca agagaaggtt
     6121 acgatgtgga tttgctgatt tcagaaatca agcgtatccg aaaaacttac aatcttgaaa
     6181 tctatatcga gcctggtgaa gccattgcgc ttaatgcggg ttatttagca actgaggtat
     6241 tagatattgt agaaaacggt atggaaatct tggttttaga cgcctctgcg acctgccata
     6301 tgcctgatgt acttgagatg ccctatcgtc cacctttgag aaatggcttt gaggcacagg
     6361 aaaaagccca tacctacaga ctttcttcta atacctgtct gacgggcgat gtgattggtg
     6421 attatagttt tgaaaatcca gtccaaatcg gagacagact ttattttcaa gacatggcca
     6481 tttattcttt tgtcaaaaat aataccttta atggtattgg attgccaagt ctctatctca
     6541 tggacgaaca gggagactgt agcttactca aagcttttgg ctatcaagac tttaaaggga
     6601 gattatcatg atggacagtc caaaaaaatt aggctatcac atgccagcag agtacgaacc
     6661 ccatcatggt accctcatga tatggccgac tcgaccagga tcatggcctt ttcaaggaaa
     6721 ggatgctaaa agagcattta ctcagatcat cgagactata gcagaagggg aaagagtcta
     6781 tcttttggtg gagcaggcct atctatctga agcccaatcc tatcttgggg acaaggttgt
     6841 ttatttagac attcccacca atgatgcctg ggcgcgtgat actggcccaa ccattctcgt
     6901 caatgataaa ggtaagaaat tagccgtgga ttgggccttc aatgcttggg gaggcaccta
     6961 tgatggtctt tatcaagatt atgaagagga tgaccaagta gccagtcgtt ttgctgaggc
     7021 cttggaaagg cctgtctatg atgctaaacc ttttgtactg gaaggaggtg caatccatag
     7081 cgatggtcaa ggaactattc tcgtaactga aagttgcttg cttagtcctg gtcgcaatcc
     7141 taacttgact aaagaggaga ttgaaaacac attattagaa agtcttggtg ctgaaaaagt
     7201 tatttggctt ccttatggta tttatcagga tgaaaccaat gaacacgtcg ataatgttgc
     7261 tgcctttgtt ggtcctgctg aggttgtttt ggcttggaca gatgacgaaa atgatcccca
     7321 gtatgccatg tcaaaagcag atctcgaact cttagaacag gaaacagatg caaaaggttg
     7381 tcacttcacc attcataaat tgcctatccc tgcagttcga caagttgtga cagaagaaga
     7441 tttgccaggc tacatctatg aagaaggaga agaagagcga tacgcaggtg aacgactagc
     7501 agcttcctac gtaaactttt atatcgccaa caaggctgtc ttggttccac agtttgagga
     7561 tgtaaacgac caagtggcct tagatatcct cagcaagtgt ttcccagacc gtaaagttgt
     7621 cggaatacca gccagagata ttctcttagg tggtggcaat atccactgta tcacccaaca
     7681 aattccagaa taggagaaaa agatgagaaa tgtaagagtt gcaaccattc agatgcaatg
     7741 cgctaaggat gtggcaacaa atatccaaac cgcagagcgt ttagtacgtc aggctgctga
     7801 gcaaggagcc caaattattc tcttgcccga gttgtttgaa catccctatt tctgtcagga
     7861 acgtcagtat gactactacc agtatgccca atctgtagcg gaaaatactg ccattcagca
     7921 ttttaaggtg attgctaagg aactacaagt tgttttacca atcagtttct atgaaaaaga
     7981 tggtaatgtc ttgtataact ctattgccgt cattgatgca gatggggaag tgctgggcgt
     8041 ttatcgaaag acccatatac cagatgacca ttattatcaa gaaaaattct atttcacgcc
     8101 tggtaacact ggtttcaagg tctggaatac tcgctatgct aagattggta tcggtatctg
     8161 ttgggatcaa tggttccctg aaacagcgcg ctgtcttgca ttgaatggtg ctgaattgct
     8221 cttttatcct acagctatcg gttcagagcc aattttggat acagatagtt gtggtcactg
     8281 gcaacgtact atgcaagggc acgcagcagc gaatattgtt ccagtcatcg cagccaatcg
     8341 ttatggttta gaggaggtta ctcctagtga ggaaaatggc ggacagagtt ccagtcttga
     8401 cttctacggt tcctccttta tgacggatga aacaggagct attctagaac gagctgaaag
     8461 acaagaagaa gctgttctgt tagctactta tgacctagac aagggagcaa gtgaacgtct
     8521 aaactggggc ttgtttcgag atagaagacc agaaatgtat agacaaatta cagattagtg
     8581 tgggagaaat gagagattca ttctgctaga ctaacttctt attagcaact ataagatact
     8641 atggcatcta gtaaatcgat ttttatgatt cgctattctt gtctattgat tagtccgtat
     8701 tttaaatatt agcaaaaaag caaatagcag taacttctgt ctatttgctt ttctttttta
     8761 tagaatatat ttctcaatag cacgcgcaac gccgtcttct tcgttgcttg aggtaacggc
     8821 atccgcaaga gatttgacat aatcgctggc atttcccatt gcaatcccaa gccctgcaaa
     8881 ctggagcatt tcgatatcgt tattagcatc gcccatggcc ataatctctg aggaatcaat
     8941 cttcaaaatc tcagcaagtc gtgaaagagc agtagccttt gtcgttccaa gtggcattgc
     9001 ttcataaatg acaggctgcg aacgaactcc actgaatcgt tggcaaagct cttcagcaaa
     9061 acgctgctca aaatcgtctg tttgttcttt tgttcctaaa aacatacctt ggaacatccg
     9121 gaactttcca ctagtcgctt cttcaagaga aatttcagtc aggtctgaaa atactagttt
     9181 agcatcattt tcaataactt gattgggctt gccaccgaga acaaaataat gtgactcgtc
     9241 aaaaagtgtc aactgaacat cactcttttc agcaaggtca tagaggtatt cgatgtcagc
     9301 tggactcagt tcttgccagt caaccaagcc ccagtcgcta gtctggtgag ttgaacaacc
     9361 gttgttaaca atcacatatt cgttctggag gtcaagcccc agttttttgt agtaggggag
     9421 gacaccgaaa agggggcgac ccgtacagag gaccagtttg acaccttttt caatggcttg
     9481 gtgaatagca gcgatgtgag cctgtgggat ttccttggct tcattgagga gggttccatc
     9541 catatccaag gctagtagtt taatcatagg tcttccttct ttatcttttg gtattattat
     9601 agcatatttt ggagaagaaa ttgatagaaa gcttgagact aattgatttt atagtttaag
     9661 atgttttgat gacaattcat gatttgaaga ggatatttgg caaagatatg ctatactatg
     9721 tttgtcaatg ttgcaactag acaaattaaa aaaccaactt aatataatag tttttttgta
     9781 agtaggtatg agtatcagat tactcaacta atctaaacaa taacggagga aatatatcat
     9841 gattttaatg acaaaaaata taaatctaac aaatgaagaa ttagagctga tacaaggtgg
     9901 agcagatccc tatggtaaag aacctaatgg ttattatcct tggcaaatgg aaccagtatt
     9961 aactatgccg gttcatggat tttgtcccag aggaaccgat gatttagtat atattgtagg
    10021 aggtaatcat ctttgcaaag gaagtgctgc gagattttaa gtaaaattta ttaggaatat
    10081 gaagaaacaa ggggagaaaa cagaggattt aatatgaaaa aacgagctat tcaaatttta
    10141 ctagcattgt ccttaatttt ttacaaatca acttggtttt ggaggctttt caattatctc
    10201 gcaaagccct atctaccagc aagtcgtgaa ttttttcaga ttctactttt gctggaaagt
    10261 ggtgttcttt tgtcagcagt catctatcta ctagtttttg caggaaagaa gatttttcat
    10321 ttcaagtggc agttgaggta ctttatctac cttttactgg gctacatcat ttcgtatatg
    10381 tctgactttc tcttttcgta tttcatatcc ccgccttcaa atcaaatttc tttgaatgaa
    10441 acgatagaaa tgatgggacg acaggagttc ccttatttct tgctcatcgt ttgcttcatc
    10501 gcccctattg ctgaggaatt gatttatcgc ggtgtgatta tgacaacctt tttcaaaaac
    10561 tcgccttggt acggagatgt tttgctttct gctattattt tcggttatat tcatatcaat
    10621 tttgctttaa ctcctcttgc ttttttcatt tatgctagtg gaggtcttat tttagctcta
    10681 ttgtatcgca tgactaaaaa tctctactat ccaatactag ttcatattct catcaatatc
    10741 actgccttct gggatgtgtg gttactccta ttttcaggaa gttagcttac taaaaaaatg
    10801 tcggaatttt ccggcatttt cttttttcac aaatagtcaa cgtttttctt tccgatactg
    10861 aagtggtgtg tagccactta tttttttgaa ttgattttga aaataagatt ggcgtgagaa
    10921 aggcagatag tgaagatagt taagaagaat aggatgttct tttttccttt ttggaaaact
    10981 tctaaaatat ggtataatga aaagataaag aagttggggg tagaagatga acattcaaca
    11041 attacgctat gttgtggcta ttgccaatag tggtactttt cgtgaagctg ctgaaaagat
    11101 gtatgttagt cagccgagtc tgtctatttc tgttcgtgat ttggaaaaag agttgggctt
    11161 taagattttt cgtcggacca gctcagggac tttcttgacc cgtcgtggga tggaatttta
    11221 tgaaaaagcg caagaattgg ttaaaggatt tgatattttt caaaatcagt atgccaatcc
    11281 tgaagaagaa aaagatgaat tttccgttgc tagccagcac tatgacttct taccaccaac
    11341 tattacggcc ttttcagagc gctatcctga ctataagaac ttccgtattt ttgaatcaac
    11401 tactgttcaa atattagatg aagtggcgca agggcatagt gagattggga ttatctacct
    11461 caacaatcaa aataaaaagg ggattatgca acgggttgaa aagttaggtc tggaggtcat
    11521 cgaattgatt cctttccata cccatattta tctctgtgag ggtcatcctt tagcccagaa
    11581 agaggaatta gtcatggagg atttagcgga tttaccaacg gttcgtttca ctcaagagaa
    11641 agacgagtac ctttattatt cagagaactt tgttgatacc agcgctagct cacagatgtt
    11701 taatgtgaca gaccgtgcca ccttgaatgg tattttggag cggacggacg cctatgcgac
    11761 aggttctgga tttttagata gtgacagtgt taatggcatt acagttattc gtctcaagga
    11821 taacctagat aaccgcatgg tctatgttaa acgtgaagaa gtggagctta gtcaagctgg
    11881 gactctcttc gtagaagtca tgcaagaata ttttgatcaa aagaggaaat catgaaaaaa
    11941 agagcaatag tggcagtcat tgtactgctt ttaattgggc tggatcagtt ggtcaaatcc
    12001 tatatcgtcc agcagattcc actgggtgaa gtgcgctcct ggattcccaa tttcgttagc
    12061 ttgacctacc tgcaaaatcg aggtgcagcc ttttctatct tacaagatca gcagctgtta
    12121 ttcgctgtca ttactctggt tgtcgtgata ggtgccattt ggtatttaca taaacacatg
    12181 gaggactcat tctggatggt cttgggtttg actctaataa tcgcgggtgg tcttggaaac
    12241 tttattgaca gggtcagtca gggctttgtt gtggatatgt tccaccttga ctttatcaac
    12301 tttgcaattt tcaatgtggc agatagctat ctgacggttg gagtgattat tttattgatt
    12361 gcaatgctaa aagaggaaat aaatggaaat taaaattgaa actggtggtc tgcgtttgga
    12421 taaggctttg tcagatttgt cagaattatc acgtagtctc gcgaatgaac aaattaaatc
    12481 aggccaggtc ttggtcaatg gtcaagtcaa gaaagctaaa tacacagtcc aagagggtga
    12541 tgtcgtcact taccatgtgc cagaaccaga ggtattagag tatgtggctg aggatcttcc
    12601 gctagaaata gtctaccaag atgaggatgt ggctgtcgtt aacaaacctc agggaatggt
    12661 tgtgcacccg agtgctggtc ataccagtgg aaccctagtc aatgccctca tgtatcatat
    12721 taaggacttg tcgggtatca atggggttct gcgtccaggg attgttcacc gtattgataa
    12781 ggatacgtca ggtcttctca tgattgctaa aaacgatgat gcgcatctag cacttgccca
    12841 agaactcaag gataaaaagt ctctccgcaa atattgggcg attgttcatg gaaatctgcc
    12901 taatgatcgt ggtgtaattg aagcgccgat tggccggagt gaaaaagacc gtaagaaaca
    12961 ggctgtaact gctaaaggga agcctgcagt gacgcgtttt cacgtcttgg aacgctttgg
    13021 cgattatagc ttagtagagt tgcaactgga gacagggcgc actcatcaaa tccgtgtcca
    13081 catggcttat atcggccatt cagtcgctgg tgatgaggtc tatggtcctc gcaagacttt
    13141 gaaaggacat ggacaatttc ttcatgccaa gactttaggt tttactcatc cgagaacagg
    13201 taagaccttg gaatttaaag cagatatccc agagattttt aaggaaacct tggagagatt
    13261 gagaaagtaa gaatgaaaaa gaaattaact agtttagcac ttgtaggcgc ttttttaggt
    13321 ttgtcatggt atgggaatgt tcaggctcaa gaaagttcag gaaataaaat ccactttatc
    13381 aatgttcaag aaggtggcag tgatgcgatt attcttgaaa gcaatggaca ttttgccatg
    13441 gtggatacag gagaagatta tgatttccca gatggaagtg attctcgcta tccatggaga
    13501 gaaggaattg aaacgtctta taagcatgtt ctaacagacc gtgtctttcg tcgtttgaag
    13561 gaattgggtg tccaaaaact tgattttatt ttggtgaccc atacccacag tgatcatatt
    13621 ggaaatgttg atgaattact gtctacctat ccagttgacc gagtctatct taaaaaatat
    13681 agtgataatc gtattactaa ttctgaacgt ctatgggata atctgtacgg ttatgataag
    13741 gttttacaga ctgctgcaga aaaaggtgtt tcagttattc aaaatatcac acaaggggat
    13801 gctcattttc agtttgggga catggatatt cagctctata actatgaaaa tgaaaccgat
    13861 tcatcgggtg aattaaagaa aatttgggat gataattcca attccttgat tagtgtggta
    13921 aaagtcaatg gcaagaaaat ttaccttggg ggcgacttag ataatgttca tggagcagaa
    13981 gacaagtatg gtcctctcat tggaaaagtt gatttgatga agtttaatca tcatttagat
    14041 acaaaaaatt ctaatacaaa aaattttata aaaaatttgt ctcctgagat aattgttcaa
    14101 acttcctcct caccaattgg ttcgtatgat agcggtcaag aaataaatag ggaatatatt
    14161 agttggcttg aatcaatggg aattcaacat ataaatgcag ccagcaaaga ctatgatgca
    14221 acagtttttg atattcgaca agacggttta ataaacattt caacttccta caagcctatt
    14281 ccaagttttc aagctggttg gcataagagt tcatatggaa actggtggta tcaagcgcct
    14341 gattctacag gagaatatgc tgttggttgg aatgaaatta agggtgaatg gtattacttt
    14401 aaccaaacgg gtatcttatt acagaatcaa tggaaaaaat ggaacaatcg ttggttctat
    14461 ttgacagact ctggtgttgc tgctaaaaat tggaagaaaa tcgctggaat ctggtattat
    14521 tttaacaaag aaaaccagat ggaaattggt tggattcaag ataaagagca gtggtattat
    14581 ttggatgttg atggctctat gaagacaggt tggcttcaat ataaggggca atggtattac
    14641 tttgctccat caggggaaat gaaaacgggc tgggtaaaag ataaagaagc ctggtactat
    14701 atggattcta ctggtatcat gaagacaggt gagatagaag ttgctggaca tcattactat
    14761 ctagaagaat caggagctat gaagcaaggc tggcataaaa aggcaaatga ttggtatttc
    14821 tacaagacag acggttcacg agctgtgggt tggatcaagg acaaggataa atggtacttc
    14881 ttgaaagaaa atggtcaatt acttgtgaac ggtaagacac cagaaggcta tactgtggat
    14941 tcaagtggtg cctggttagt ggatgtttcg atcgagaaat ctgctacaat taaaactaca
    15001 agtcattcag aaataaaaga atccaaagaa gtagtgaaaa aggatcttga aaataaagaa
    15061 acgagtcaac atgaaagtgt tacaaattct tcaactagtc aagatttgac atcctcaact
    15121 tcacaaagct ctgaaacgag tgtaaacaaa tcggaatcag aacagtagta gaaaagaagg
    15181 ttttagggcc ttctttttcc tatcaactct tttctatttc ctgttattca tgttataatg
    15241 gataaatatg aataatcgga gtgagactat gaaatacaaa cggattgtct ttaaggtggg
    15301 tacttcttct ctgacaaatg aggatggaag tttatcacgt agtaaggtaa aggatattac
    15361 ccagcagttg gctatgctgc acgaggctgg tcatgagttg attttggtgt cttcaggtgc
    15421 cattgcggct ggttttggag ccttaggatt taaaaagcgt ccgactaaga ttgctgataa
    15481 acaggcttca gcagcggtag ggcaagggct tttgttggaa gaatatacaa ccaatcttct
    15541 cttgcgtcaa atcgtttctg cacaaatctt gctgacccaa gatgattttg tggataagcg
    15601 tcgttataaa aatgcccatc aggctttgtc ggttttactc aatcgtgggg caattcctat
    15661 catcaatgag aatgatagtg tcgttattga tgaggtcaag gttggggaca atgacactct
    15721 aagtgcccaa gtagcggcga tggtccaagc agaccttttg gttctcttga cagatgtgga
    15781 cggtctctat actggaaatc ctaattcaga tccaagagcc aaacgcttgg agagaataga
    15841 gaccatcaat cgtgagatta ttgatatggc tggtggagct ggttcgtcaa acggaactgg
    15901 gggtatgtta accaaaatca aggctgcaac tatcgcgacg gaatcaggag ttcctgttta
    15961 tatctgctca tccttgaaat cagattccat gattgaggcg gcagaggaga ccgaggatgg
    16021 ttcttacttt gttgctcaag agaaggggct tcgtacccag aaacaatggc ttgccttcta
    16081 tgctcagagt caaggttcta tttgggttga taaaggggct gcggaagctc tctctcaaca
    16141 tggaaagagt cttctcttat ctggtattgt tgaagcagaa ggagcctttt cttacggtga
    16201 tatcgtgaca gtatttgaca aggaaagtgg aaaatcactt ggaaaaggac gcgtgcaatt
    16261 tggagcatct gctttggagg atatattgcg ttctcaaaaa gccaagggtg tcttgattta
    16321 ccgtgacgac tggatttcca ttactcctga aatccaacta ctttttacag aattttagag
    16381 gtaaactatg gtgagtagac aagaacaatt tgaacaggta caggctgtta aaaaatcgat
    16441 taacacagct agtgaagaag tgaaaaatca agccttgcta gccatggctg atcacttagt
    16501 agctgctact gaggaaattt tagcggctaa tgccctcgat atggcagcgg ctaaggggaa
    16561 aatctcagat gtgatgttgg atcgtcttta tttggatgca gatcgtatag aagcgatggc
    16621 aagaggaatt cgtgaagtgg ttgccttacc agatccaatc ggtgaagttt tagaaacaag
    16681 tcagcttgaa aatggtttgg ttatcacaaa aaaacgtgta gctatgggtg tcatcggtat
    16741 tatctatgaa agccgtccaa atgtgacgtc tgatgcggct gctttgactc ttaagagtgg
    16801 aaatgcggtt gttcttcgta gtggtaagga tgcctatcaa acaacccatg ccattgtcac
    16861 agccttgaag aagggcttgg agacgactac tattcaccca aatgtgattc aactggtgga
    16921 agatactagc catgaaagta gttatgctat gatgaaggcc aagggctatc tagacctcct
    16981 cattcctcgt ggaggagctg gcttgatcaa tgcagtggtt gagaatgcga ttgtacctgt
    17041 tatcgagaca gggactggga ttgtccatgt ctatgtggat aaggatgcag acgaagacaa
    17101 ggcgctgtct atcatcaaca atgctaaaac cagtcgtcct tctgtttgta atgccatgga
    17161 ggttctgctg gttcatgaag ataaggcagc aagcatcctt cctcgcttgg atcaaatgct
    17221 ggttgcagag cgtaaggaag ctggactgga accaattcaa ttccgcttgg atagcaaagc
    17281 aagccagttt gtttcaggtc aagcagctga gacccaagac tttgacaccg agtttttaga
    17341 ctatgtcctt gctgttaagg ttgtgagcag tttagaagaa gcggttgcgc acattgaatc
    17401 ccacagcacc catcattcgg atgctattgt gacggaaaat gctgaagctg cagcatactt
    17461 tacagatcaa gtggactctg cagcggtgta tgttaatgcc tcaactcgtt tcacagatgg
    17521 aggacaattt ggtcttggtt gtgaaatggg gatttctact cagaaattgc acgcgcgtgg
    17581 tccaatgggc ttgaaggaat tgactagcta caagtatgtg gtcactggtg atggacagat
    17641 aagggagtaa gagatgaaga ttggatttat cggtttgggg aatatgggtg ctagtttagc
    17701 caagtctgtc ttgcaggcta gaccgtcaga tgagattctc cttgccaatc gtagtcaagt
    17761 caaggtggat gctttcatcg ctaacttcgg tggtcagact tctaacaatg aagaaatatt
    17821 cgaagaagca gatgtgattt ttctaggtgt taagcctgct cagttttctg aactgctttc
    17881 tcaataccag accatccttg aaaaaagaga aagtcttctt ttgatttcga tggcagctgg
    17941 attgatctta gaaaaactag caagtcttat cccaagccaa caccgaatta ttcgtatgat
    18001 gcctaatacc cctgcttcta tcgggcaagg agtgattagt tatgccttgt ctcctaattg
    18061 cagggctgag gacagtgagc tcttttgtca gcttttatcc aaggctggtc tcttggttga
    18121 attaggagaa agcttaatca atgcagcgac aggtcttgca ggctgtggac cagcctttgt
    18181 ctatctcttt attgaggcct tggcagatgc aggtgttcag acgggattac cacgagaaac
    18241 agccttgaaa atggcagccc aaactgtggt aggagctggg caattggtcc tagaaagcca
    18301 gcaacatcct ggagttttga aagatcaagt ttgtagtcca ggcggttcga ctattgctgg
    18361 cgtagcaagc ctagaagcgc atgcttttcg aggaacggtc atggaggcag ttcatcaagc
    18421 ctataaacga acacaagaac taggtaaata agaggtagtt ttatctgcct cttttatggt
    18481 ggttgatact cttcgaaaat caaattcaaa ctgcgtcagc ttcaccttgc cgtactcaag
    18541 tacagcctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat gaaatgagaa
    18601 gacaaaaaga ttgtcacaaa cccctatttt tttgatagaa tagaagtagt aaaaaagaaa
    18661 tgagttagac atgtcaaaag gatttttagt ctctcttgag ggaccagagg gagcaggcaa
    18721 gaccagcgtt ttagaggctc tgctaccaat tttagaggta aaaggggtaa aggtgctgac
    18781 gacccgtgaa cctggcggag tcttgattgg ggagaagatt cgggaagtga ttttggatcc
    18841 aagtcatact cagatggatg ctaaaacaga gctacttctc tatattgcca gtcgcagaca
    18901 gcatttggtg gaaaaagttc ttccagccct tgaagctggc aagttggtca tcatggatcg
    18961 ttttatcgat agttctgttg cctatcaggg atttggtcgt ggcttagata ttgaagccat
    19021 tgactggctc aatcagtttg cgacagatgg cctcaaaccc gatttgacac tctattttga
    19081 catcgaggtg gaagaagggc tggctcgtat tgctgctaat agtgaccgcg aggttaatcg
    19141 tttggatttg gaagggttgg acttgcataa aaaagttcgt caaggctacc tttctctcct
    19201 ggaaaaagaa ggaaatcgca ttgtcaagat tgatgctagt ctccctttgg agcaagttgt
    19261 ggaaactacc aaggctgtct tgtttgacgg aatgggcttg gccaaatgaa acaagatcaa
    19321 ctaaaggctt ggcaaccagc tcagtttgac cgttttgtcc gtatcttaga acaagaccag
    19381 ctcaatcacg cctatctctt ttcaggtttc tttggaagct tggaaatggc gcaattttta
    19441 gctaagagcc tcttttgtac ggataaagtt ggcgtcttac catgtgagaa atgccgaagt
    19501 tgcaagctga ttgaacagga agagtttcca gatgtcacct tgattaagcc agtcaatcag
    19561 gtcatcaaga cagaacgcat tcgggaattg gtgggacagt tttctcaagc agggattgaa
    19621 agccagcaac aggtctttat catcgagcaa gcggataaaa tgcatcccaa cgcagccaat
    19681 tctctgctca aggtcatcga agaaccccag agtgaagttt atattttctt cttgactagc
    19741 gatgaggaaa agatgttacc gacaatccga agtcggactc agatcttcca ctttaaaaag
    19801 caagaagaaa aacttatctt actcttagaa caaatgggac ttgttaagaa aaaagcgact
    19861 cttttagcta agtttagtca atcgcgagct gaagcagaaa agttggctaa tcaggcaagt
    19921 ttttggacct tggtcgatga aagtgaacgc ctgctgactt ggttagtagc taagaaaaaa
    19981 gaaagttatc tacaggttgc caaattagcc aacttggcag atgataagga aaaacaggat
    20041 caggttttac ggattcttga agttctctgt gggcaggacc tcttgcaggt aagagtaaga
    20101 gtgattctac aagatttact agaagctaga aaaatgtggc aagctaatgt cagctttcaa
    20161 aatgccatgg aatatctggt cttgaaagaa atataaactc aaaaatgaat gataaagaaa
    20221 ggaaagggct gttttatgga caaaaaagaa ttatttgacg cgctggatga tttttcccaa
    20281 caattattgg taactttagc cgatgtggaa gccatcaaga aaaatctcaa gagcttggta
    20341 gaagaaaata cagctcttcg cttggaaaat agtaagttgc gagaacgctt gggtgaggtg
    20401 gaagcagacg ctcccgtcaa ggccaagcat gttcgcgaaa gtgtccgtcg tatttaccgt
    20461 gatggatttc acgtatgtaa tgatttttat ggacaacgtc gagagcagga cgaagaatgt
    20521 atgttctgtg atgagttgtt atacagggag taagcatgca gattcaaaaa agttttaagg
    20581 ggcagtctcc ctatggcaag ctgtatctag tggcaacgcc gattggcaat ctagatgata
    20641 tgacttttcg tgctatccag accttgaaag aagtggactg gattgctgct gaggatacgc
    20701 gcaatacagg tcttttgctc aagcattttg acatttccac caagcagatc agttttcatg
    20761 agcacaatgc caaggaaaaa attcctgatt tgattggttt cttgaaagca gggcaaagta
    20821 ttgctcaggt ctctgatgcc ggtttgccta gcatttcaga ccctggtcat gatttggtta
    20881 aggcagctat tgaggaagaa attgcagttg ttacagttcc aggtgcctct gcaggaattt
    20941 ccgccttgat tgccagtggt ttagcgccgc agccacatat cttttacggc tttttaccga
    21001 gaaaatcagg ccagcaaaag caatttttcg actcgaaaaa agactatcct gaaactcaga
    21061 ttttttatga atcgccccat cgtgtggcag atacattgga aaatatgcta gaagtctacg
    21121 gtgaccgctc ggtagtcttg gttagagaat tgaccaaaat ctatgaagaa taccaaagag
    21181 gtacaatttc tgaattgctg gaaagcatct ctgaaacgtc tctcaagggt gaatgtcttc
    21241 tgattgttga aggtgccagc aaaggtgtgg aggaaaagga tgaggaagac ttgttcttag
    21301 aaatccaagc ccgtatccag caaggcatga agaaaaatca agctattaag gaagtcgcta
    21361 agatttacca gtggaataaa agtcagctct acgctgccta ccacgactgg gaagaaaatc
    21421 aagaaaatga ctaaacaggg aagtttgcct tcttcccttt ttttgttata ctagtagaag
    21481 aaaaaattag aaagatttgt gggtgttaaa caagccagtg ccttgttttg atatgaactt
    21541 aggttccacc caaagaggta ttagtgtcgt gtctcaatct tatatcaatg ttatcggtgc
    21601 tggtttggca ggttctgaag cagcttacca aatcgcagag cgtggtattc cagttaaact
    21661 atatgaaatg cgtggtgtca agtctacacc ccagcataaa acagacaatt ttgctgagtt
    21721 ggtttgttcc aattctttgc gtggggatgc tttgacaaat gcagttggtc ttctcaagga
    21781 agaaatgcgt cgcttgggtt ctgttatctt ggaatctgct gaggctacac gtgttcctgc
    21841 cggtggagcc cttgcggtgg atcgtgatgg tttctctcaa atggtgaccg aaaaagttgc
    21901 caaccacccc ttgattgaag tggttcgtga tgaaattaca gaattgccga cagatgttat
    21961 tacggttatc gctactggtc ctttgacaag tgatgccttg gctgaaaaga ttcatgccct
    22021 taatgacggt gatggttttt atttctacga tgcggcagcg cctattatcg atgtcaacac
    22081 tatcgatatg agcaaggtct acctcaaatc acgttatgat aagggagaag cggcctacct
    22141 caatgcccct atgaccaagc aagaatttat ggatttccat gaagctttgg tcaatgcaga
    22201 agaagcaccg cttaattctt ttgaaaaaga aaagtacttt gaaggatgta tgcctatcga
    22261 agttatggcc aaacgtggca ttaaaactat gctttatggc cctatgaagc cagtcggtct
    22321 tgagtatccg gacgactaca caggacctcg tgatggagaa tttaaaacac cttatgcggt
    22381 tgtgcaactt cgtcaggata atgcagctgg tagcctctac aatatcgttg gtttccagac
    22441 ccacctcaaa tggggagaac aaaagcgtgt cttccaaatg attccgggtc ttgaaaatgc
    22501 ggagtttgtc cgttatggtg tcatgcatcg caattcttac atggattcac caaatcttct
    22561 tgagcagact taccgttcca agaaacaacc aaatctcttc tttgctggtc agatgacggg
    22621 ggtggaaggc tatgttgagt cggcggcttc gggcttagtt gcgggaatta acgcagctcg
    22681 tctcttcaag gaagaaagcg aggttatttt ccccgagacg acagcgattg gaagcttagc
    22741 tcattacatt acccatgccg acagcaaaca tttccaacca atgaatgtca attttgggat
    22801 catcaaggag ttggaaggcg agcgtatccg tgataagaag gctcgttatg aaaaaattgc
    22861 agagcgtgcc cttgccgact tagaggaatt tttgactgtc taattttttt gaaagaattg
    22921 ctcatgatac tataaaaatc ttagaaattg tgataaaata ggtaggatga aagaaggaga
    22981 gtgaaaatgg cgaatcccaa gtataaacgt attttaatca agttatcagg tgaagccctt
    23041 gccggtgaac gtggcgtagg gattgatatc caaacagttc aaacaatcgc aaaagagatt
    23101 caagaagttc atagcttagg tatcgaaatt gcgcttgtta ttggtggagg aaatctctgg
    23161 cgtggagaac ctgcagcaga agcaggtatg gaccgtgttc aggcagatta cactggaatg
    23221 cttgggactg ttatgaatgc tcttgtgatg gcagattcat tgcaacaagt tggggttgat
    23281 acgcgtgtac aaacagctat tgctatgcaa caagtggcag agccttatgt ccgtggacgt
    23341 gcccttcgtc accttgaaaa aggccgtatc gttatctttg gtgctggaat tggttcacca
    23401 tacttctcga cagatacaac agcggccctt cgtgcagctg aaatcgaagc agatgccatc
    23461 ctcatggcta aaaatggcgt cgatggtgtg tacaatgccg atcctaagaa ggacaagaca
    23521 gccgttaagt ttgaagaatt gacccaccgt gatgttatca acaaaggtct tcgtatcatg
    23581 gactcaacag cctcaaccct ctcaatggac aacgacattg acttggttgt cttcaacatg
    23641 aaccaatcag gcaacatcaa acgtgtcgta tttggtgaaa atatcggaac aacagtttca
    23701 aataatatcg aagaaaagga ataagaaaga atatggctaa cgtaattatt gaaaaagcta
    23761 aagagagaat gacccagtct caccaatcac ttgctcgtga atttggtggt atccgtgctg
    23821 gtcgtgccaa tgcaagcttg cttgaccgtg tacatgtaga atactatgga gtcgaaactc
    23881 ctcttaacca aatcgcttca attacgattc cagaagcgcg tgttttgttg gtaacaccat
    23941 ttgacaagtc ttcattgaaa gacatcgaac gtgccttgaa cgcttctgat cttggtatca
    24001 caccggctaa tgacggttct gtgattcgct tggttatccc agctcttaca gaagaaactc
    24061 gtcgtgacct tgctaaagaa gtgaagaagg tcggcgaaaa tgctaaagtg gctgtccgca
    24121 atatccgtcg cgatgctatg gacgaagcta agaaacaaga aaaagcaaaa gaaatcactg
    24181 aagacgaatt gaagactctt gaaaaagata ttcaaaaagt aacagacgat gctgttaaac
    24241 acatcgacga tatgactgcc aacaaagaga aagaactttt ggaagtctaa aaataaacag
    24301 aaaaactcag ttggcattgc tggctgagtt ttattcgaaa gaaggaaata tgaatacaaa
    24361 tcttgcaagt tttatcgttg gactgatcat cgatgaaaac gaccgttttt actttgtgca
    24421 aaaggatggt caaacctatg ctcttgctaa ggaagaaggc caacatacag taggggatac
    24481 ggtcaaaggt tttgcataca cggatatgaa gcaaaaactc cgcctgacaa ccttagaagt
    24541 gactgccact caggaccaat ttggttgggg acgtgtcaca gaggttcgta aggacttggg
    24601 tgtctttgtg gatacaggcc ttcctgacaa ggaaatcgtt gtgtcactcg atattctccc
    24661 tgagctcaag gaactctggc ctaagaaggg cgaccaactc tacatccgtc ttgaagtgga
    24721 taagaaagac cgtatctggg gtctcttggc ttatcaagaa gacttccaac gtcttgctcg
    24781 tcctgcctac aacaacatgc agaaccaaaa ctggccagcc attgtttacc gtctcaagct
    24841 atcaggaact tttgtttacc taccagaaaa taatatgctt ggttttattc atcctagcga
    24901 gcgttacgca gagccacgtt tggggcaagt attagatgcg cgcgttattg gtttccgtga
    24961 agtggaccgc actttgaacc tctccctcaa accacgctcc tttgaaatgt tggaaaacga
    25021 tgctcagatg attttgactt atttggaaag caatggcggt ttcatgacct taaatgacaa
    25081 gtcatctcca gacgacatca aggcaacctt tggcatttct aaaggtcagt tcaagaaagc
    25141 tttaggtggt cttatgaagg ctggtaaaat caagcaggac cagtttggta cagagttgat
    25201 ttagggaggc ttatgagaaa atcattttac acttggctca tgaccgagcg caatcctaaa
    25261 agtaacagtc ccaaagcaat tttggcagac ctcgcttttg aagagtcagc ctttccaaaa
    25321 catacagatg attttgatga ggtcagtcgc tttttggagg agcatgccag tttctctttt
    25381 aacctaggag attttgacag catttggcag gaatatctag aacactagca tttattcatt
    25441 gggtttgggc tagtaatttc tccatccctc tgctataata aaaagaaata aaaggattag
    25501 agaggttctt tatttgaagg aacattcaat agacattcaa ctgagtcatc cagatgacct
    25561 gtttcatctt tttggttcca atgaacgcca tcttcgtttg atggaagaag agcttgatgt
    25621 tgtgattcat gctcgtacgg agattgtcca ggttttggga gaagagtctg cctgtgagga
    25681 agcccgtcaa gttattcagg ctttgatggt cttggtaaat cgtgggatga ccgttggtac
    25741 gccagatgta gtcactgcga ttagcatggt caaaaatgat gaaattgaca agtttgtcgc
    25801 cctttacgaa gaagaaatta tcaaagataa tactgggaaa cctatccgtg tcaaaaccct
    25861 agggcaaaag ctttatgtgg acagtgtcaa acagcatgat gtgacctttg gaattgggcc
    25921 agcaggtaca gggaagacct tccttgcagt gaccttggca gtgactgccc ttaaacgtgg
    25981 gcaagtcaag cgaattatcc taactcgtcc agcggtggaa gcgggagaga gtcttggatt
    26041 tcttccgggt gatcttaagg agaaggtgga tccttacctt cgtcctgttt acgatgcctt
    26101 gtatcaaatt cttgggaaag accaaacgac tcgtctcatg gagcgtgaaa ttatcgaaat
    26161 tgcgcccctt gcctatatgc gtggtcggac cttggatgat gcctttgtca ttctcgatga
    26221 ggcgcaaaat acgaccatca tgcagatgaa gatgttcttg actcgtttag gttttcattc
    26281 taagatgatt gtcaatggag atattagtca gattgatctg ccacgtaatg tcaagtccgg
    26341 tttgattgat gcccaagaaa agctcaagaa catttaccaa attgactttg ttcatttttc
    26401 agctaaggat gtggttcgcc atccagttgt cgctcagatt atccgagctt atgaaccagc
    26461 tccagttaaa aaagaagaga gtgaagaatt agagtctcaa cctctgtctg aaggatagtt
    26521 cttttgtact taaagttatc tcaatgctaa gtataaattt gctttttaaa tgttttattc
    26581 aatatcctta tattagatta gaaacgtttc aagcggagga aacgtatgga atcaatattt
    26641 gtgaaatttg cccagtatcc gtctatagaa acggagcgtt tattgcttag acctgtaact
    26701 ttggatgatg cggaagcaat gtttgactat gcctcggaca agggtaatac acgttacact
    26761 tttccaacca atcaaagctt ggaagaaacc aagaataaca ttgctcagtt ctatttggct
    26821 aatcccttgg gacgttgggg aatagaacta aaaagcaatg gtcagtttat tggaaccatt
    26881 gacttgcaca agattgattc tgttcttaag aaggcagcta ttggctacat tatcaataaa
    26941 aagtattgga atcaaggatt aacgacagaa gccaatcgtg ctgtgattga gctagctttt
    27001 gagaagatag ggatgaataa gttgactgcc cttcacgata aggacaatcc tgcgtcagga
    27061 aaggtcatgg agaaatcagg catgcgtttt tcccatgcag aaccatatgc ttgtatggac
    27121 cagcatgaaa aagatcgaat cgttacaaga gttcattatg tcttgaccaa ggaagactat
    27181 tttgcaaata aataagcagt tgaaaagaaa tttttcgact gttttttctt cctcttacga
    27241 ataatctaag agaggagaaa atatggaagc aattatcgag aaaatcaaag agtataaaat
    27301 catcgtcatc tgtactggtc tgggcttgct tgtaggcgga tttttcctgc taaagccagc
    27361 tccacaaaca cctgtaaagg aaacgaattt gcaggctgaa gttgcagctg tttccaagga
    27421 tttggtatcc gaaaaggaag tgaacaagga agagaaggaa gaaccagttg aacaagatct
    27481 aatcacagta gatgtcaaag gtgctgtcaa atcgccaggg atttatgact tgcctgtagg
    27541 tagtcgagtc aatgatgctg ttcagaaggc tggtggcttg acagagcaag cagacagcaa
    27601 gtcgctcaat ctagctcaga aagttagtga tgaggctctg gtttacgttc ctactaaggg
    27661 agaagaagca gttagtcaac agactggttc ggggacagct tcttcaataa gcaaggaaaa
    27721 gaaggtcaat ctcaacaagg ccagtctgga agaactcaag caggtcaagg gactgggagg
    27781 aaaacgagct caggacatta tcgaccatcg tgaggcaaat ggcaagttca agtcagtaga
    27841 cgagctcaag aaggtctctg gcattggtgg caaaacaata gaaaagctta aagactatgt
    27901 tacagtggat taagaatttc tctattcccc taatttacct gagttttcta ttactttggc
    27961 tttattacgc tattttctca gcatcttatc ttgctttgtt gggctttgtt tttctgctag
    28021 tctgtctctt tatccaattt ccgtggaaat ctgctggtaa agttctaata atttgcggaa
    28081 tctttggatt ttggtttgtt tttcaaaatt ggcaacagag tcaagcgagt caaaatctgg
    28141 cggattctgt tgaaagggta cggattttgc ctgatactat taaggttaat ggtgatagtc
    28201 tatcctttcg tggcaagtct aacggtcgtg ctttccaagt ctattataaa ctccagtccg
    28261 aggaggagaa agaagccttt caagctttaa ccgacctgca tgagatagga ctagaaggga
    28321 agctttcgga gccagaaggg cagagaaatt ttggtggctt taattaccaa gcctatctga
    28381 agactcaggg aatttaccag actctcaata tcaaaacaat ccagtcactt caaaagattg
    28441 gcagttggga tataggagaa aacttgtcca gtttacgtcg aaaggctgtg gtttggatta
    28501 agacgcactt tccagaccct atgcgcaatt acatgacagg actcttgctg ggacatctgg
    28561 acaccgactt tgaggagatg aatgagcttt attccagtct aggaattatc cacctctttg
    28621 ccctatctgg tatgcaggta ggttttttca tgaatggatt taagaaactt ctcttgcgat
    28681 tgggcttgac ccaagaaaag ttgaaatggc tgacttatcc cttttccctt atctatgcgg
    28741 gactaactgg attttcagca tcggttattc gcagtctctt gcaaaagcta ctggctcaac
    28801 atggggttaa gggcttggat aattttgcct tgacggtgct tgtcctcttt attgtcatgc
    28861 caaacttttt cttgacagca ggaggagtct tgtcctgcgc ttatgctttt atcctgacca
    28921 tgaccagcaa agaaggggag gggctcaagg ctgttactag tgaaagtcta gtcatctcct
    28981 tgggcatatt gcccattcta tccttctatt ttgcggaatt tcaaccttgg tctatccttt
    29041 tgacctttgt cttttccttt ctatttgact tgaccttctt accgctcttg tctattttat
    29101 ttgtcctttc ctttctctat ccagtcattc agctgaactt tatctttgaa tggttggagg
    29161 gcattattcg cttggtgtca caggtgacaa gtagacctct ggtctttgga caacccaatg
    29221 catggttttt aatcctattg ttaatttcct tggctttggt ctatgatttg agaaaaaaca
    29281 ttaaaaagct aacggtattg tgcttattga ttacagggct ctttctcctg atcaagcatc
    29341 cactggaaaa tgaaatcacc atgctggatg tggggcaagg agaaagtatt ttcctacggg
    29401 atgtaactgg gaaaaccatt ctcatagatg taggtggtaa ggcagaatct tataagaaaa
    29461 tcgaaaaatg gcaagaaaag atgacgacca gcaatgccca gcgaaccttg attccctatc
    29521 tcaaaagtcg aggagtagct aagattgacc agctaatttt gactaacacg gacaaggaga
    29581 atgttggaga tttgtcagag gtgaccaagg ctttccatgt aggggagatt ctagtatcaa
    29641 aagacagtct gaaacagaag gaatttgtgg cagaactaca gacgactcaa acaaaggtgc
    29701 gtagtatgac agtaggggag aacttgccca tttttggaag tcagttagaa gttctatctc
    29761 caaggaaaat gggagatgga ggacacgatg acaccctagt tctgtatggg aaattcttgg
    29821 ataagcaatt tctcttcacg ggaaatttgg aggagaaagg agagaaggac ttgctgaagc
    29881 actatccaga cttgaaagta aatgttttga aagctagcca acatggcaat aaaaaatcat
    29941 caagtccagc ctttctagaa aaactcaaac cagagcttac tcttatctca gttggaaaga
    30001 gcaatcgaat gaaactcccc catcaggaaa cattgacacg actggaaggt atcaatagca
    30061 aagtttatcg aactgaccag caaggagcta tacgttttaa ggggttggat agttggaaaa
    30121 tcgaaagtgt tcgataggaa ggataaatgt tgtagattag tgaaataaac taaaaatttg
    30181 ttgcataata atgataaaaa tggtataatg aaaacgtatt caatattgag gatataaaat
    30241 cattaaaaat cagcaaaagt tgttttatta gttagtttat aatctattgg tcttcttcag
    30301 tccagtgtat ctgctgtgac agccactaaa agttacaagt atgattggaa tacggttttg
    30361 gaatatagta ccaactatca cgaccatcag tatgcttgga ttccggaatg gtctcgttat
    30421 tacagctatt ctgagtataa agttggcgga ggctggaact acgctcgtta tgaggtcata
    30481 aactactata ctggaggtta ttaatcctta aagagtgaga aaaggagggc tggatatgtt
    30541 aaatcttact catgttacct taaaaacgcg acaagtcatc ttgcaagatg cggattttac
    30601 ctttaaaaag ggtaggattt atggccttct tgctatcaat ggctcgggaa agacgacact
    30661 attccgagct atgagcaagt tgcttcccct tagtagtgga cacatcgcag ttcctccttc
    30721 tttgttttat tatgagagcg ttgaatggct ggatggaaac ttaagtggga tggactacct
    30781 tcgtctcata aaaaacatct ggaagtcaga cctaaacttg agagatgaaa tcgcctactg
    30841 ggaaatggct gactatatca gtcttcccat ccgcaagtat tccttaggga tgaagcaacg
    30901 cttggtgatt gctatgtatt ttctcagtca ggccaaatgc tggctcatgg atgagattac
    30961 aaatggctta gacgagtatt atcgacagaa gttttttgat aggctagcac aaatcgatag
    31021 acaagaacag ctggttcttt taagttccca ctataaggaa gagttggttg atatctgcga
    31081 tagagtagta accattcatc aggggcagat agaagaggtt tagtttatga aagatgttag
    31141 tctattttta ttgaaaaaag ttttcaaaag tcgtttaaac tggattatct tacttttatt
    31201 tgcatctgta ctcggtgtta ccttttattt aaatagtcag actgcaaact cacacagctt
    31261 ggagagcagg ttggaaagtc gcattgcagc caacgagagg gctatcaatg aaaatgaaga
    31321 gaaactctcc caaatgtctg ataccagctc ggaggaatac cagtttgcta aaaataattt
    31381 agacgtgcaa aaaaatcttt tgacgcgaaa gacagaaatt ctaactttac taaaagaagg
    31441 gcgctggaaa gaagcctact atctgcagtg gcaagatgaa gagaagaatt atgaatttgt
    31501 atcaaatgac ccgactgcta gctctggctt aaaaatgggg gttgaccgcg aacggaagat
    31561 ttaccaagcc ctgtatccct tgaacataaa agcacatact ttggagtttc cgacccacgg
    31621 gattgatcag attgtctgga ttttagaggt tatcatccca agcttgtttg tggttgcgat
    31681 tatttttatg ctaacacaac tatttgcaga aagatatcaa aatcatctgg acacagctca
    31741 cttatatcct gtttcaaaag tgacatttgc aatatcctct cttggagttg gagtgggata
    31801 tgtaactgtg ctgtttatcg gaatctgtgg cttttctttt ctagtgggaa gtctgataag
    31861 tggttttgga cagttagatt atccctaccc aatttatagc ttagtgaatc aagaagtaac
    31921 tattgggaaa atacaagatg tattatttcc tggcttgctc ttagctttct tagcctttat
    31981 cgtcattgtg gaagttgtgt acttgattgc ttactttttc aagcaaaaaa tgcctgtcct
    32041 ctttctttca ctcattggga ttgttggttt attgtttggc atccaaacca ttcagcctct
    32101 tcaaaggatt gcacatctga ttccctttac ttacttgcgt tcagtggaga ttttatctgg
    32161 aagattacct aagcaaattg ataatgtcaa tctaaattgg agcatgggga tggtcttgct
    32221 tccttgcctg attatccttt tgttagtggg gattctattt atcgaaagct ggggaagttc
    32281 acgtaaaaag gaagttttta aagtttagtt ttcctatagg gaagctaaag aaaaactaac
    32341 atagggagag aatcaacttg gttctctctt tttgattcga aaaccaaacc aaaatacaaa
    32401 cacaaacttt tcaaaaaata actttttatc ttgacaagag ctagaaaact tggtatcata
    32461 taaaagttga gaaaagcaga agtgagagct tctcgccttg tgacattaag ttgcctggcc
    32521 ctacggatga aaagtttcga agaaacgcta tcataacgtg cgggcttgta tatttacaag
    32581 tccgctattg tttttctcta ataaaacaaa agaggtgaaa accatagcaa agcaagactt
    32641 attcatcaat gatgagattc gtgtacgtga agttcgcttg attggtcttg aaggagaaca
    32701 gctaggtatc aagccactca gtgaagcgca agctttggct gataacgcta atgttgacct
    32761 agtattgatt caaccccaag ccaaaccgcc tgttgcaaaa attatggact acggtaagtt
    32821 caaatttgag taccagaaga agcaaaaaga acaacgtaaa aaacaaagcg ttgttactgt
    32881 gaaagaagtt cgtctaagtc caacaattga caagggtgac tttgatacaa aacttcgtaa
    32941 tgcacgtaag ttccttgaaa aaggaaataa agttaaggta tctattcgct ttaagggtcg
    33001 tatgattacc cataaagaga ttggtgcaaa agttttagcc gagtttgctg aagcaactca
    33061 agatattgcc atcatcgaac aacgtgctaa aatggatgga cgtcaaatgt tcatgcaatt
    33121 ggcgccagcg actgacaaaa aataattgtc agaaagttaa ataaaggaga aaaaatcatg
    33181 ccaaaacaaa aaacacaccg cgcatcagct aaacgtttca aacgtacagg ttctggtgga
    33241 cttaaacgtt tccgtgctta cacttctcac cgtttccacg gaaaaactaa gaaacaacgt
    33301 cgtcatcttc gtaaagcatc tatggtgcat tcaggagatt acaaacgtat caaagcaatg
    33361 cttactcgct tgaaataata gcttgactgt aagtaaacaa ttctaggaaa tatttggagg
    33421 aaataaaaca tggcacgtgt taaaggtggc gttgtatcac gcaaacgtcg taaacgtatt
    33481 cttaaattag caaaaggtta ctatggagct aaacacatct tgttccgtac tgcaaaagaa
    33541 caagtaatga actcttacta ctatgcatac cgtgaccgtc gtcagaaaaa acgtgacttc
    33601 cgcaaattgt ggattactcg tatcaatgcg gcagctcgta tgaacggact ttcatactca
    33661 caattgatgc atggtttgaa attggctgag attgaagtta accgtaaaat gcttgctgac
    33721 ttggctgtta acgatgcagt agctttcaca gctcttgcag atgcagctaa agcaaaactt
    33781 ggtaaataat aactgatgag actggaacag gattgtccag tctttttaaa aataaaggag
    33841 aaagatatgg cttcaaaaat gctacacact tgcttacgag tagaaaatct tgaaaaatca
    33901 atcgcatttt atcaagatgc ttttggtttt aaagaattgc gtcgcagaga ttttccagac
    33961 catgccttca cgattgtcta tctaggtctt gagggtgatg attatgagtt ggagttgact
    34021 tataactacg atcacggtcc gtatgtggtt ggtgatgggt ttgcccatat cgccctcagt
    34081 acacctgatc ttgaggcact tcatcaagaa cacagtgcaa aaggctatga agtgactgag
    34141 ccaaatggtc taccaggaac tacaccaaac tattactttg ttaaagaccc tgatggatat
    34201 aaggtcgaag tcattcgtga aaaataattt cgtgcaagtt aagtagaata ttcgttttct
    34261 acttgacttt ttttagctga aagagtatac taataaaaat tcaaccttta aggggagtcc
    34321 agagagactc acaaggtgtc agataaaaga atagtgcaat tttctagagg agaccttttg
    34381 agtgtgctct cttgtgttgt acgattttaa ctgaggcctt gcactagcaa ggtcttttct
    34441 ttatctggtc cccttaaaat ttaaggagga aaagttatga atctcacatg taagaagcgt
    34501 ttgggtgtca ttcggttgga aaccatgaag gtggttgcac aagaggaaat cgcgccagca
    34561 atctttgaat tagtcctaga aggagaaatg gttgaagcca tgcgagcagg ccaatttctt
    34621 catctgcgtg taccagacga tgcccatctc ttacgtcgtc ctatttcaat ttcgtctatt
    34681 gacaaggcaa acaagcagtg tcacctcatt tatcggattg agggagctgg gactgcaatt
    34741 ttttcaacct taagtcaggg agacactctt gatgtgatgg ggcctcaggg aaatggtttt
    34801 gacttgtctg accttgatga gcagaatcag gttctccttg ttggtggtgg gattggtgtt
    34861 ccacccttgc ttgaggtggc caaggaattg catgaacgtg gagtgaaagt agtgacagtc
    34921 ctcggttttg ctaataagga tgctgttatt ttgaaaacgg aattggctca gtatggtcag
    34981 gtctttgtaa cgacagatga tggttcttat ggcatcaagg gaaatgtttc cgttgttatc
    35041 aatgatttag atagtcagtt tgatgctgtt tactcgtgtg gggctccagg aatgatgaag
    35101 tatatcaatc aaacctttga tgatcaccca agagcctatt tatctctgga atctcgtatg
    35161 gcttgtggga tgggagcttg ctatgcctgt gttctaaaag taccagaaag cgagacggtc
    35221 agccaacgcg tctgtgaaga tggtcctgtt ttccgcacag gaacagttgt attataagga
    35281 gaaaattatg actacaaatc gattacaagt gtctctacct ggtttggatt tgaaaaatcc
    35341 gattattcca gcatcaggct gttttggctt tggacaagag tatgccaagt actatgattt
    35401 aaacctttta ggttctatta tgatcaaggc gacaaccctt gaaccacgtt ttgggaaccc
    35461 aactccaaga gtagcagaga cgcctgctgg tatgctcaat gcaattggct tgcaaaatcc
    35521 tggtttagag gttgttttgg ctgaaaagct accttggctg gaaagagaat atccaaatct
    35581 tcctattatt gccaatgtag ctggtttttc aaaacaagag tatgcagctg tttctcatgg
    35641 gatttccaag gcaactaatg taaaagctat cgagctcaat atttcttgtc ccaatgttga
    35701 ccactgtaat catggacttt tgattggtca agatccagat ttggcttatg atgtggtgaa
    35761 agcagctgtg gaagcctcag aagtgccagt ttatgtcaaa ttaaccccga gtgtgaccga
    35821 tatcgttact gtcgcaaaag ctgcagaaga tgcgggagca agtggcttga ccatgatcaa
    35881 tactctggtt ggaatgcgct ttgacctcaa aaccagaaaa ccaatcttgg ccaatggaac
    35941 aggtggaatg tcaggtccag cagtctttcc agtagccctc aaactcatcc gccaagtagc
    36001 ccaaacaaca gacctgccta tcattggaat ggggggagtg gattcggctg aagctgccct
    36061 agaaatgtat ctggctgggg catctgctat cggagttgga acagctaact ttaccaatcc
    36121 ttatgcctgc cctgacatca tcgaaaattt accaaaagtc atggataaat acggtattag
    36181 cagtctggaa gaactccgtc aggaagtaaa agagtctctg aggtaaactg caatcaatct
    36241 gttcttgatt ttttattagt ttgtaatatg aatttaggag aattttggta caataaaata
    36301 aataagaaca gaggaagaag gttaatgaag aaagtaagat ttattttttt agctctgcta
    36361 tttttcttag ctagtccaga gggtgcaatg gctagtgatg gtacttggca aggaaaacag
    36421 tatctgaaag aagatggcag tcaagcagcg aatgagtgga tttttgatac tcattatcaa
    36481 tcttggttct atataaaagc agatgctaac tatgctgaaa atgaatggct aaagcaaggt
    36541 gacgactatt tttacctcaa atctggtggc tatatggcca aatcagaatg ggtagaagac
    36601 aagggagcct tttattatct tgaccaagat ggaaagatga aaagaaatgc ttgggtagga
    36661 acttcctatg ttggtgcaac aggtgccaaa gtaatagaag actggatcta tgattctcaa
    36721 tacgatgctt ggttttatat caaagcagat ggacagcacg cagagaaaga atggctccaa
    36781 attaaaggga aggactatta tttcaaatcc ggtggttatc tactgacaag tcagtggatt
    36841 aatcaagctt atgtgaatgc tagtggtgcc aaagtacagc aaggttggct ttttgacaaa
    36901 caataccaat cttggtttta catcaaagaa aatggaaact atgctgataa agaatggatt
    36961 ttcgagaatg gtcactatta ttatctaaaa tccggtggct acatggcagc caatgaatgg
    37021 atttgggata aggaatcttg gttttatctc aaatttgatg ggaaaatagc tgaaaaagaa
    37081 tgggtctacg attctcatag tcaagcttgg tactacttca aatccggtgg ctacatggca
    37141 gccaatgaat ggatttggga taaggaatct tggttttacc tcaagtttga tggcaaaatg
    37201 gctgaaaaag aatgggtcta cgattctcat agtcaagcct ggtactactt caaatccggt
    37261 ggttacatga cagccaatga atggatttgg gataaggaat cttggtttta tctcaaatct
    37321 gatgggaaaa tagctgaaaa agaatgggtc tacgattctc atagtcaagc ttggtactac
    37381 ttcaaatccg gtggttacat gacagccaat gaatggattt gggataagga atcttggttt
    37441 tacctcaagt ctgatggcaa aatggctgaa aaagaatggg tctacgattc tcatagtcaa
    37501 gcctggtact acttcaaatc tggtggctac atggcgaaaa atgagacagt agatggttat
    37561 cagcttggaa gcgatggtaa atggcttgga ggaaaagcta caaataaaaa tgctgcttac
    37621 tatcaagtag tgcctgtcac agccaatgtt tatgattcag atggtgaaaa gctttcctat
    37681 atatcgcaag gtagtgtcgt atggctagat aaggatagaa aaagtgatga caagcgcttg
    37741 gctattacta tttctggttt gtcaggctat atgaaaacag aagatttaca agcgctagat
    37801 gctagtaagg actttatccc ttattatgag agtgatggcc accgttttta tcactatgtg
    37861 gctcagaatg ctagtatccc agtagcttct catctttctg atatggaagt aggcaagaaa
    37921 tattattcgg cagatggcct gtattttgat ggttttaagc ttgagaatcc cttccttttc
    37981 aaagatttaa cagaggatac aaactacagt gctgaagaat tggataaggt atttagtttg
    38041 ctaaacatta ataatagcct tttggagaac aagggcgcta cttttaagga agccgaagaa
    38101 cattaccata tcaatgccct ttatctcctt gcccatagtg ccctagaaag taactgggga
    38161 agaagtaaaa ttgccaaaga taagaataat ttctttggca ttacagccta tgatacgacc
    38221 ccttaccttt ctgccaagac atttgatgat gtggataagg gaattttagg tgcaaccaag
    38281 tggattaagg aaaattatat cgatagggga agaactttcc ttggaaacaa ggcttctggt
    38341 atgaatgtgg aatatgcttc agacccttat tggggcgaaa aaattgctag tgtgatgatg
    38401 aaaatcaatg agaagctagg tggcaaagat tagtactata agtgaatatg atttgagtga
    38461 atagtaagtt aaaaatcctg atttcaagta aaatcaggat tttttcatgg atgcaatttt
    38521 tttggagtct ggtgtgacgc ggagggtctt ttgtcctgtg taagtgacaa agccgggttt
    38581 tccaccagtt ggtttattga gttttttgac ttcaatcata tctacctgca ccagattcga
    38641 caggcgccct tgagagaagt aggcagctaa ctctgctgcg tctgtcttga ctgcatcaga
    38701 tgggtcaaga tttcctgaga tgacaacatg gcttccagga atgtccttag catggaacca
    38761 aagttcctcc ttgcgggcca ttttaaaggt caattcctca ttttgaagat tgtttcgtcc
    38821 gacatagatg atggttttgc catcgcttgc tagatattgt tctagttttt tgcgtttctg
    38881 gattttctcc cgttgtcttc tgcggataaa acctgtttga atcaattctt cgcggatttc
    38941 agcgatttct tccagtccag cttggttgag gacggtttct acactttcca gatagagaat
    39001 agtggctttg gtttcttcaa tcaaatcagt caagtatttg acagcttctt tgagtttctg
    39061 ataccgttta aaatagcgtt gggcattctg gttgggagtc agagccttat caagcgcaat
    39121 catgataggt tggttggtat agtagttgtc taggataacc tggtcttggt cgttaggcac
    39181 ttggtgtagg aaggttgtca gcaattctcc tttttgacga aattcttcag cgttgtctgt
    39241 cgccagtaac tctttttcct gttttttgag tttgtgtcgg tttttctgaa gttcattttc
    39301 aacacgacga atcagttcac tggcctgctg tttgacgcgg tcgcgctcag ccttatcctt
    39361 atagtaggtg tccaacaaat cagaaagatt tgcaaaaggc tctcccacct gatttgcaaa
    39421 aggaactgga ctgaaggaag tctcagtcaa gcatggcttg gtttcctgat tgaaaaaatt
    39481 tcggaaagcg gaaagttttt cactaaccag tatcctttcc aattcatttg ccgtatcgcg
    39541 tcccagacct tgaaagaggc tttgaagatt ttttgctgtt agttcttggg tttgcaggat
    39601 ttcaaagagc ttttcatcct tgatagtaaa aggattgaga gattctgtac ttggcggagc
    39661 gatataggtc gatcctggaa gtaaggtgcg gtagctattt tgtgaaaagc cgacgtgttt
    39721 gataacttcg aggattttat gactgctttt atcgaccagt agaatattac tgtgtttccc
    39781 cataatttcg ataatcaagg tagcctggat atggtctcca atctcgtttt tattggaaac
    39841 tgtaatttcc acaatacggt cattttccac ttgctcaatc gactcaatca gggccccctg
    39901 caaatacttt ctcaaaacca tgataaaggt agaaggttgg gctggatttt caaaagtcgt
    39961 ttgggtcagc tgaatgcgtc caaaaactgg atgggcagaa aggagcaggc gatggctttg
    40021 gcgattgctg cggatttgca agaccaactc ttgttcaaaa ggctgattga ttttctggat
    40081 gcgaccattc actaattcgc ttcgcaattc ctcaactatg tggtgtaaaa aaaatccgtc
    40141 aaatgacatc gttctctcct tgtgattgta ttccatagta ttatatcaaa aaggtagaat
    40201 aaaatcatgg aaatgtggta taataaagcc aagtaaagag aaacgagaag cacatgtata
    40261 ttgaaatggt agatgaaact ggtcaagttt caaaagaaat gttgcaacaa acccaagaaa
    40321 ttttggaatt tgcagcccaa aaattaggaa aagaagacaa ggagatggca gtcacttttg
    40381 tgaccaatga gcgtagtcat gaacttaatc tggagtaccg tgacaccgac cgtccgacag
    40441 atgtcatcag ccttgagtat aaaccagaat tggaaattgc ctttgacgaa gaggatttgc
    40501 ttgaaaatcc agaattggca gagatgatgt ctgagtttga tgcctatatt ggggaattgt
    40561 tcatctctat cgataaggct catgagcagg ccgaagaata tggtcacagc tttgagcgtg
    40621 agatgggctt cttggcagta cacggctttt tacatattaa cggctatgat cactatactc
    40681 cggaagaaga agcggagatg ttcggtttac aagaagaaat tttgacagcc tatggactca
    40741 caagacaata aacgaaaatg gaaaaatcgt gacttgatat ccagtttaga atttgccatc
    40801 acagggattt ttactgctat caaggaagaa cgaaatatgc gaaaacatgc agtgacggct
    40861 ctagtggtca tccttgcagg ttttgttttt caggtgtcac gaatcgaatg gctctttctt
    40921 ctattgagta ttttcttggt agtagccttt gagattatca actctgctat tgaaaatgtg
    40981 gtggatttgg ccagtcacta tcacttttcc atgctggcta aaaatgccaa ggatatggcg
    41041 gccggcgcgg tattagtggt ttctcttttc gcagccttaa caggcgcatt gatttttctc
    41101 ccacgaatct gggatttatt attttaaaca gtaagaggaa attatgactt ttaaatcagg
    41161 ctttgtagcc attttaggac gtcccaatgt tgggaagtca acctttttaa atcacgttat
    41221 ggggcaaaag attgccatca tgagtgacaa ggcgcagaca acgcgcaata aaatcatggg
    41281 aatttacacg actgataagg agcaaattgt ctttatcgac acaccaggga ttcacaaacc
    41341 taaaacagct ctcggagatt tcatggttga gtctgcctac agtacccttc gcgaagtgga
    41401 caccgttctt ttcatggtgc ctgctgatga agcgcgtggt aagggggacg atatgattat
    41461 cgagcgtctc aaggctgcca aggttcctgt gattttggtg gtgaataaaa tcgataaggt
    41521 ccatccagac cagctcttgt ctcagattga tgacttccgt aatcaaatgg actttaagga
    41581 aattgttcca atctcagccc ttcagggaaa taacgtgtct cgtctagtgg atattttgag
    41641 tgaaaatctg gatgaaggtt tccaatattt cccgtctgat caaatcacag accatccaga
    41701 acgtttctta gtttcagaaa tggttcgcga gaaagtcttg cacctaactc gtgaagagat
    41761 tccgcattct gtagcagtag ttgttgactc tatgaaacga gacgaagaga cagacaaggt
    41821 tcacatccgt gcaaccatca tggtcgagcg cgatagccaa aaagggatta tcatcggtaa
    41881 aggtggcgct atgcttaaga aaatcggtag catggcccgt cgtgatatcg aactcatgct
    41941 aggagacaag gtcttcctag aaacctgggt caaggtcaag aaaaactggc gcgataaaaa
    42001 gctagatttg gctgactttg gctataatga aaaagaatac taagtagagg tgggctcatg
    42061 cctgcttctt gttttacaga aggaggactt atgcctgaat tacctgaggt tgaaaccgtt
    42121 tgtcgtggct tagaaaaatt gattatagga aagaagattt cgagtataga aattcgctac
    42181 cccaagatga ttaagacgga tttggaagag tttcaaaggg aattgcctag tcagattatc
    42241 gagtcaatgg gacgtcgtgg aaaatatttg cttttttatc tgacagacaa ggtcttgatt
    42301 tcccatttgc ggatggaggg caagtatttt tactatccag accaaggacc tgaacgcaag
    42361 catgcccatg ttttctttca ttttgaagat ggtggcacgc ttgtttatga ggatgttcgc
    42421 aagtttggaa ccatggaact cttggtgcct gaccttttag acgcctactt tatttctaaa
    42481 aaattaggtc ctgaaccaag cgaacaagac tttgatttac aggtctttca atctgccctt
    42541 gccaagtcca aaaagcctat caaatcccat ctcctagacc agaccttggt agctggactt
    42601 ggcaatatct atgtggatga ggttctctgg cgagctcagg ttcatccagc tagatcttcc
    42661 cagactttga cagcagaaga agcgacagct attcatgacc aaaccattgc tgttttgagc
    42721 caggctgttg aaaaaggcgg ttccaccatt cggacctata ccaatgcctt tggggaagat
    42781 ggaagcatgc aggattttca tcaggtctat gataagactg gtcaagaatg tgtacgctgt
    42841 ggtaccatca ttgagaaaat tcaactaggc ggacgaggca cccacttttg tccaaactgt
    42901 caaaggaggg actgatgaga aaaatcatcg gaatcactgg gggaattgcc tctggtaagt
    42961 caactgtgac aaattttcta agacagcaag gctttcaagt agtggatgcc gacgcagtcg
    43021 tccaccaact acagaaacct ggtggtcgtc tgtttgaggc tctagtacag cactttgggc
    43081 aagaaatcat tcttgaaaac ggagaactca atcgccctct cctagctagt ctcatctttt
    43141 caaatcctga agagcaaaaa tggtctaagc aaattcaagg ggagattatc cgtgaggaac
    43201 tggctacttt gagagaacag ttggctcaga cagaagagat tttcttcatg gatattcccc
    43261 tactttttga gcaggactac agcgattggt ttgctgagac ttggttggtc tatgtggacc
    43321 gagatgccca agtagaacgc ttaatgaaaa gggaccagtt gtccaaagat gaagctgagt
    43381 ctcgtctggc agcccagtgg cctttagaaa aaaagaaaga tttggccagc caggttcttg
    43441 ataataatgg caatcagaac cagcttctta atcaagtgca tatccttctt gagggaggta
    43501 ggcaagatga cagagattaa ctggaaggat aatctgcgta ttgcctggtt tggtaatttt
    43561 ctgacaggag ccagtatttc tttggttgta ccttttatgc ccatcttcgt ggaaaatcta
    43621 ggtgtaggga gtcagcaagt cgctttttat gcaggcttag caatttctgt ctctgctatt
    43681 tccgcggcgc tcttttctcc tatttggggt attcttgctg acaaatacgg ccgaaaaccc
    43741 atgatgattc gggcaggtct tgctatgact atcactatgg gaggcttggc ctttgtccca
    43801 aatatctatt ggttaatctt tcttcgttta ctaaacggtg tatttgcagg ttttgttcct
    43861 aatgcaacgg cactgatagc cagtcaggtt ccaaaggaga aatcaggctc tgccttaggt
    43921 actttgtcta caggcgtagt tgcaggtact ctaactggtc cctttattgg tggctttatc
    43981 gcagaattat ttggcattcg tacagttttc ttactggttg gtagttttct atttttagct
    44041 gctattttga ctatttgctt tatcaaggaa gattttcaac cagtagccaa ggaaaaggct
    44101 attccaacaa aggaattatt tacctcggtt aaatatccct atcttttgct caatctcttt
    44161 ttaaccagtt ttgtcatcca attttcagct caatcgatcg gccctatttt ggctctttat
    44221 gtacgcgact tagggcagac agagaatctt ctttttgtct ctggtttgat tgtgtccagt
    44281 atgggctttt ccagtataat gagtgcagga gtcatgggca agctaggtga caaggtgggc
    44341 aatcatcgtc tcttggttgt cgcccagttt tattcagtca tcatctatct cctctgtgcc
    44401 aatgcctcta gcccccttca actaggactc tatcgtttcc tctttggctt gggaaccggt
    44461 gccttgattc ccggggttaa tgccctactc agcaaaatga ctcccaaagc cggcatttcg
    44521 agggtctttg ccttcaatca ggtattcttt tatctgggag gtgttgttgg tcccatggca
    44581 ggttctgcag tagcaggtca atttggctac catgctgtct tttatgcgac aagcctttgt
    44641 gttgccttta gttgtctctt taacctgatt caatttcgaa cattattaaa agtaaaggaa
    44701 atctagtgcg agtaaaaatt aatctcaaat gctcctcttg tgacagtatc aattacctaa
    44761 ccagtaaaaa ttcaaaaacc catccagaca agattgaggt tttaaagtat tgtcccaagg
    44821 aaagaaaagt aaccctacat cttgaatcta agtagatttt atggtaaaat aatagggatt
    44881 ttaaggagtt tgatatgtat aacctattat taaccatttt attagtatta tctgttgtga
    44941 ttgtgattgc aattttcatg caaccaacca aaaaccaatc cagcaatgta tttgatgcca
    45001 gttcaggtga tttgtttgaa cgcagtaaag ctcgcggttt tgaagctgta atgcagcgtt
    45061 tgacagggat tttagtcttt ttctggctag ccattgcctt agcattgacg gtattatcaa
    45121 gtagataaga aaataatggg caggactagg tctttgcctc tttttatttt taaaggatgt
    45181 ttgagaaggt tttacagtaa aagaaaatta aaaaatctag aaagaaaata tgaaagatag
    45241 aataaaagaa tatttacaag acaagggaaa ggtgactgtt aatgatttgg ctcaggcttt
    45301 gggaaaagac agttccaagg attttcgtga gttgattaaa accttgtcct taatggaaag
    45361 aaagcaccag attcgctttg aagaagatgg cagtctgacc ttggaagcca agaaaaaaca
    45421 tgagattacc ctcaagggga tttttcatgc ccataaaaat ggttttggtt ttgtcagcct
    45481 agaaggggaa gaggacgacc tttttgtagg gaaaaatgat gtcaactatg ctattgatgg
    45541 tgataccgtc gaggtagtga ttaagaaagt cgctgaccgc aataagggaa cagcagcaga
    45601 agccaaaatt attgatatcc tagaacacag tttgacaaca gttgtcgggc aaatcgttct
    45661 ggatcaggaa aagcctaagt atgctggcta tattcgttca aaaaatcaga aaatcagtca
    45721 accgatttat gttaagaaac cagccctaaa gttagaagga acagaagttc tcaaggtctt
    45781 tatcgataaa tacccaagca agaaacatga tttctttgtc gcgagtgttc tcgatgtggt
    45841 gggacactca acggatgtcg gaattgatgt tcttgaggtt ttggaatcaa tggacattgt
    45901 atccgagttt ccagaagctg ttgttaagga agcagaaagt gtgcctgatg ctccgtctca
    45961 aaaggatatg gaaggtcgtc tggatctaag agatgaaatt acctttacca ttgacggtgc
    46021 ggatgccaag gacttggacg atgcagtgca tatcaaggct ctgaaaaatg gcaatctgga
    46081 gcttggggtt cacatcgcag atgtttctta ttatgtgacc gaggggtctg cccttgacaa
    46141 ggaagccctt aaccgtgcga cttctgttta cgtgacagac cgagtggtgc caatgcttcc
    46201 agaacgacta tcaaatggca tctgctctct caatccccaa gttgaccgcc tgacccagtc
    46261 tgctattatg gagattgata aacatggtcg tgtggtcaac tataccatta cacaaacagt
    46321 tatcaagacc agttttcgta tgacctatag cgatgtcaat gatatcctag ctggcgatga
    46381 agaaaagaga aaaaaatatc ataaaattgt accaagtatc gaactcatgg ccaagcttca
    46441 tgaaacttta gaaaacatgc gtgtgaaacg tggagctctc aattttgata ccaatgaagc
    46501 gaagatttta gtggataaac aaggtaagcc tgttgatatc gttcttcggc agcgtggtat
    46561 tgccgagcgg attattgagt cttttatgtt gatggctaat gaaacagttg ccgaacattt
    46621 cagcaagttg gatttgcctt ttatctatcg aattcacgag gagcctaagg ctgaaaaggt
    46681 tcagaagttt attgattatg cttcgagttt tggcttgtgc atttatggga ctgccagtga
    46741 gattagtcag gaggcacttc aagacatcat gcgtgctgtt gagggagaac cttatgcaga
    46801 tgtattgtcc atgatgcttc ttcgctctat gcagcaggct cgttattcgg agcacaatca
    46861 cggccactat ggactagctg ctgactatta tactcacttt accagtccaa ttcgtcgtta
    46921 tccagacctt cttgttcacc gtatgattcg agattacggc tgttctaagg aaatagcaga
    46981 gcattttgaa caagtgattc cagagattgc gacccagtct tccaaccgtg aacgtcgtgc
    47041 catagaagct gagcgtgaag tcgaagccat gaaaaaggct gagtatatgg aagaatacgt
    47101 gggtgaagag tatgatgcag ttgtatcaag tattgtcaaa ttcggtctct ttgtcgaatt
    47161 gccaaacaca gttgaaggct tgattcacat cactaatcta cctgaatttt atcatttcaa
    47221 tgagcgtgat ttgactcttc gtggagaaaa atcaggtatc actttccgag tgggtcagca
    47281 gatccgtatc cgtgttgaaa gagcggataa aatgactgga gagattgatt tttcattcgt
    47341 acctagtgag tttgatgtga ttgaaaaagg cttgaaacag tctagtcgta gtggcagagg
    47401 gcgtggttca aatcgtcgtt cggataagaa ggaagacaag agaaaattag gacgctcaaa
    47461 tgataagcgt aagcattcac aaaaagacaa gaagaaaaaa ggaaagaaac ctttttacaa
    47521 ggaagtagct aagaaaggag ccaagcatgg caaagggcga gggaaaggtc gtcgcacaaa
    47581 ataaaaaggc acgccacgac tatacaatcg tagatacgct agaggcaggg atggtcctga
    47641 ctggaactga aatcaagagt gtacgagctg ctcgaattaa tctcaaggat ggctttgctc
    47701 aagtgaaaaa tggagaagtt tggctgagca atgttcatat cgcgccttac gaagagggca
    47761 atatctggaa ccaggaacca gaacgtcgtc gtaaactcct gctccataaa aagcaaattc
    47821 aaaaattgga acaagagacc aaagggacag gaatgacctt agttcccctt aaggtctata
    47881 taaaagatgg ctacgctaag cttcttttag gacttgccaa agggaagcat gactatgaca
    47941 aacgggagtc tatcaaacgt cgtgagcaaa atcgagatat cgcgcgtgtg atgaaagctg
    48001 ttaatcagcg ataaaaagag gaattgaaaa tggaaaaatt agttgcctat aaacgcatgc
    48061 ctttgtggaa taaacaaaca atgcctgaag ctgttcagca aaagcacaat acaaaagttg
    48121 ggacttgggg gaaaattact gtcttgaagg gagctctcaa gtttattgaa ttgacagaag
    48181 aaggggaagt tctagctgaa cacctctttg aagcaggggc agacaatcca atggcccaac
    48241 ctcaagcctg gcaccgagtg gaagctgcca cagatgatgt ggaatggtac ttggaatttt
    48301 attgtaaacc tgaggattat tttgctaaaa aatacaatac caatcctgtt cattcagagg
    48361 tcctagaggc catgcagaca gtgaaacaag ggaaagcttt ggatttgggt tgtggtcagg
    48421 ggcgtaattc tctttttcta gcccagcaag attttgatgt gacggctgta gatcaaaatg
    48481 gactggctct tgaaatcttg caaagcattg tggagcagga agatttggac atgcctgttg
    48541 gcctttacga tatcaattca gctagcattg gacaagaata tgattttatc gtttcaacag
    48601 ttgttctcat gtttctacaa gcggaccgca ttccagctat tattcaaaat atgcaggaga
    48661 aaaccagtgt tggtggttac aaccttatcg tttgtgccat ggacacggag gattatcctt
    48721 gctcggttaa tttcccattc acctttaaag aaggagaact ggcagactat tacaaggatt
    48781 gggaattggt taagtacaat gaaaatccag gccatttgca tcgtcgcgat gagaatggca
    48841 atcgtattca actacgcttt gcgaccttac tagctaagaa aatcaagtaa acacacatga
    48901 agattaggaa ttttcctgat cttttttctt ttttacgaat gatatagaaa aggagggaat
    48961 tcatgtttgt tgcgagagat gctaggggag aattggtaaa tgtgttagag gataaacttg
    49021 agaagcaagc atacacctgc ccagcttgtg gaggccagct ccatttgcgt caaggaccaa
    49081 gtgtacggac gcattttgcc cataaatcct taaaagactg tgattttttc tttgaaaatg
    49141 aaagtccaga acacctggcc aataaggaat ccctctatca ctggttgaaa aaagagacaa
    49201 aggttcaatt agagtacccg ctttcagaac ttaaacagat tgcggatgta tttgtaaatg
    49261 gcaatctagc tctagaagtt cagtgtagtc ccttgcctca gaaagtcctt aaagagcgaa
    49321 gtgagggata tcgtagtcag ggttaccaag tactgtggtt gctgggtcaa aaactgtggc
    49381 tcaaggagcg tttgactcgt ctacagcaag gttttcttta tttcagtcaa aacatgggct
    49441 tttatgtttg ggaattagac aaggaaaaac aagttttaag actcaaatac ctgatttacc
    49501 aggatctccg cggtaaactc cattatcaaa tcaaggaatt ttcctatggt caaggtagtt
    49561 tattggaaat attgcgtctt ccctataaga gacaaaaaat atctcatttt acagtttctg
    49621 aggacaagga catctgtcgc tatatccggc aacaacttta ttatcaaaat ctcttttgga
    49681 tgaaagaaca agcagaagcc tatcaaaagg gagaaaatat cctgacttat ggactgaaag
    49741 aatggtatcc acaaattcga ccaatagtgg gcaaattttt ccagattgaa caagacttga
    49801 ctagctatta tcagtacttt tatacctatt accaaaaaaa tcctcaaaat gattggcaaa
    49861 agctttatcc accagccttt tatcagcaat atttcttgaa aaatatggta gaataaaaag
    49921 gatggaggaa tctaatggta ttacaaagaa atgaaataaa tgaaaaagat acatgggatc
    49981 tatcaacgat ctacccaact gaccaggctt gggaagaagc cttaaaagat ttaacagaac
    50041 aattggagac agtagcccag tatgaaggcc atctcttgga tagtgcggat aacctactag
    50101 aaatcactga attttctctt gaaatggaac gccagatgga gaagctttac gtttatgctc
    50161 atatgaagaa tgaccaggat acacgtgaag ctaagtatca agagtactat gccaaggcca
    50221 tgacactcta cagccagtta gaccaagcct tttcattcta tgatcctgaa tttatggaga
    50281 ttagcgaaaa gcagtatgct gactttttag aagctcaacc aaagctgcag gtttatcaac
    50341 actattttga caagctcttg caaggcaagg atcacgttct ttcacaacgt gaagaagaat
    50401 tattggctgg agctggagaa atctttggtt cagcaagtga aaccttcgct atcttggaca
    50461 atgcggatat tgtgttccct tatgtcctag acgatgatgg taaagaagtt cagctatctc
    50521 atgggactta cacacgtttg atggagtcta aaaaacgtga ggttcgccgt ggtgcctatc
    50581 aagctcttta tgcgacttac gaacaattcc aacacaccta tgccaaaacc ttgcaaacca
    50641 atgttaaggt gcaaaattac cgtgctaaag ttcgtaacta caagagtgct cgtcatgcag
    50701 ccctcgcagc gaattttgtt ccagaaagtg tttatgacaa tttggtagca gcagttcgca
    50761 agcatttgcc actcttacat cgctatcttg agcttcgttc aaaaatcttg gggatttcag
    50821 atctcaagat gtacgatgtc tacacaccgc tttcatctgt tgaatacaat tttacctacc
    50881 aagaagcctt gaaaaaagca gaagatgctt tggcagtctt gggtgaggat tacttgagcc
    50941 gtgtcaaacg tgccttcagc gagcgttgga ttgatgttta cgaaaatcaa ggcaagcgtt
    51001 caggtgccta ctctggtggt tcttacgata ccaatgcctt tatgcttctc aactggcagg
    51061 acaatctgga caatctcttt actcttgttc atgaaacagg tcacagtatg cattcaagct
    51121 atactcgtga aactcagcct tatgtttacg gagattactc tatctttttg gctgagattg
    51181 cctcaactac caatgaaaat atcttgacgg agaaattatt ggaagaagtg gaagacgacg
    51241 caacacgctt tgctattctc aataacttcc tagatggttt ccgtggaaca gttttccgcc
    51301 aaactcaatt tgctgagttt gaacacgcca ttcaccaagc agatcaaaat ggggaggtct
    51361 tgacaagcga tttcctaaat aaactctacg cagacttgaa ccaagagtat tatggtttga
    51421 gtaaggaaga caatcctgaa atccaatacg agtgggctcg cattccacac ttctactata
    51481 actactatgt atatcaatat tcaactggct ttgcggccgc ctcagccttg gctgaaaaaa
    51541 ttgtccatgg tagtcaagaa gaccgtgacc gctatatcga ctacctcaag gcaggtaagt
    51601 cggactatcc acttaatgtc atgagaaaag ctggtgttga tatggagaag gaagactacc
    51661 tcaacgatgc ctttgcagtc tttgaacgcc gtttaaatga gtttgaagcc cttgttgaaa
    51721 aaataggatt ggcataaaat ggttgaatcg tatagtaaga atgctaacca taacatgcgt
    51781 cgtcctgtcg tcaaagaaga aattgtagac ttgatgcgtc agcgtcaaaa gcaagtcaca
    51841 ggttccttga aagaattgga agactttgcc cgcaaggaaa atattcctat tattccccat
    51901 gaaacggttg cttatttccg ttttcttatg gaaaccatgc agcctaaaaa tattctggaa
    51961 attgggacgg ctatcggttt ttcagctctc ttgatggctg aacatgcgcc aaatgctaag
    52021 attacaacta ttgatcgtaa tccagaaatg attggttttg ccaaggaaaa ttttgcccag
    52081 tttgacagtc gcaagcaaat cactctccta gagggagatg cggtggatgt cttatctaca
    52141 ctgacagagt cttatgattt cgtctttatg gattctgcca agtctaaata catcgtcttt
    52201 ctgccagaaa tcctcaaaca tttggaagtt ggtggtgtgg ttgtcttgga tgatattttt
    52261 caaggtggtg atgttgccaa ggatattatg gaagtccgtc gtggtcagcg aaccatttat
    52321 cgaggccttc aaaaattatt tgatgcaacc ttagacaatc cagaactcac cgcaacatta
    52381 gtgcctttag gagatggtat tctcatgctt cgtaaaaatg tagcagatgt tcaactgtct
    52441 gaaagcgaat gattttcaga aaaatttaag aaaaaatagt aaaatagata gagtaacact
    52501 tatctcaaag gagtagacat gaagaaaaaa ttattggcag gtgccatcac actattatca
    52561 gtagcaactt tagcagcttg ttcgaaaggg tcagaagggg cagaccttat cagcatgaaa
    52621 ggggatgtca tcacagaaca tcaattttat gagcaagtga aaagcaaccc ttcagtccaa
    52681 caagtcttgt taaatatgac catccaaaaa gtttttgaaa aacaatatgg ctcagagctt
    52741 gatgataaag aggttgatga tactattgcc gaagaaaaaa aacaatatgg cgaaaactac
    52801 caacgtgtct tgtcacaagc aggtatgact cttgaaacac gtaaagctca aattcgtaca
    52861 agtaaattag ttgagttggc agttaagaag gtagcagaag ctgaattgac agatgaagcc
    52921 tataagaaag cctttgatga gtacactcca gatgtaacgg ctcaaatcat ccgtcttaat
    52981 aatgaagata aggccaaaga agttctcgaa aaagccaagg cagaaggtgc tgattttgct
    53041 caattagcca aagataattc aactgatgaa aaaacaaaag aaaatggtgg agaaattacc
    53101 tttgattctg cttcaacaga agtacctgag caagtcaaaa aagccgcttt cgctttagat
    53161 gtggatggtg tttctgatgt gattacagca actggcacac aagcctacag tagccaatat
    53221 tacattgtaa aactcactaa gaaaacagaa aaatcatcta atattgatga ctacaaagaa
    53281 aaattaaaaa ctgttatctt gactcaaaaa caaaatgatt caacatttgt tcaaagcatt
    53341 atcggaaaag aattgcaagc agccaatatc aaggttaagg accaagcctt ccaaaatatc
    53401 tttacccaat atatcggtgg tggagattca agctcaagca gtagtacatc aaacgaatag
    53461 tccaaatcaa tgagtcaggg aaaaaactcg acttcaggaa aaaatgaagc aaacattccc
    53521 acaataaaac gcatagtaca aggtttgtac tgccccccaa aaaagttaga caattaattt
    53581 atccgaagga tttagttctg tattgcacag agctaagtcc ttttagtttt atcttaattc
    53641 tcttattgtt gtaataatca atatagtcta taatggcttg ttccaattga ttaagtgatt
    53701 taaatgtttg ctcatagcca taaaacattt cggattttaa aatgccaaag aaagattcca
    53761 tcctaccgtt gtcttggctg tttcctttgc gtgacataga tgcttgaatt cccttactct
    53821 ctaggaagcg atgataagaa tcgtgttggt attgccagcc ttggtcacta tggagaatcg
    53881 tattctcgta gtgcttctct ttgaatgctg ttccaacatt aacgatcaat caatttaatc
    53941 atgtacctaa gattagaatt gtttatccca aatttatttg aaagcttctc taagctatat
    54001 ccttgttttc taagttcata gatctgaact ttatcatcat aagttaattt cataataaaa
    54061 acaccccaaa agttagattt tttctgtcta acttttgggg tgtagttcat gtacacctga
    54121 tatgatgcgt tttataattt taaagacttt ttgaccagcc tcatttttta acttgatact
    54181 cagtgaaaag caaagattaa actaggaagc tagctgtagg ctgctcaaag aacagctttg
    54241 aggttgcaga taaaacttgt gaggtaacca acatatataa tgtgaagctg acgtggtttg
    54301 aatagatttt agaagggtat gagtctggaa gttttaatgg ataatgcaag attccataga
    54361 atgggtaagc tagagttctt atgtgaagag tttgggcata aacttttacc ttttcctccc
    54421 tactcatctt agtatagaaa agtgaatcta aaatagtaca taactgcttc taaaacattc
    54481 ttataaattg atttaaattc tcaaatcata ttattcagtt cttatttcat tttgctctac
    54541 aatcctgttg agaagacacg tgttcatatc aaaaaggtat tggcaagttg caataccttt
    54601 ttacaaggtt cttttgtctt atttttgttt caactgacta tatctcctat ggttctagtt
    54661 cagaaggcta ggctataatt atgattgata agaagtatca ttccaagtat tgagagtgaa
    54721 tgtttcaaaa tcatgggttt ctataatggt caggctggca tttgctagac cgccatcttt
    54781 acgaagaagt ggttctttat agcctaggag agtacgaaga ctggcagtaa gattggcgcc
    54841 gtgtccgaca attagaatac gctcagctgg actatctttt aatgatttga taaattggat
    54901 ggtccgctga gttgtactat agagggattc ggctccgaac attcgagtgt caaattgagc
    54961 aagatttgaa cgaaaagcct ggatttgttg cgggtaaata gcttccaggg ttgcaatttt
    55021 caaaccttct aacttcccaa gttgccattc acggagatta ggaacgattt ctaaagaaca
    55081 gggggtatgg agttgacttt ggataatctc agcagatttg accgctcgag gtaaatcact
    55141 tgaataaatc tgatcaaaag gaatttcctt gagatactgg ccaagtcgtt ttagggtttc
    55201 aatggatcca ggaagaagag gagaatcacc gctagcacct tgaaaacgac cttcttggtt
    55261 ccagagggta cgaccgtggc ggacaaagta gagtttcatt acttgatgtc ctccaaaata
    55321 tctacaaagt ctgcctttac aaagctagcc aagtcttgtg gcgcgacgat aatgctgtgt
    55381 ccgacttcgc ctgcagagac aatcattcga tccaaatcta gagcaatttt atcgataaaa
    55441 atgtgataat tgtgtttctg acgaattccg acaggattat tggctccatg aatgtaacca
    55501 gttgtttttt ctaagtcctt ttgtggaatc atgctcactt ttttattgcc agaaatttta
    55561 gctagtttct tttcagacaa gtgctgagtg atagggacaa ttccgataat cggtccggtc
    55621 ttgtctccca aaagcgccaa ggttttgaaa atctgatctc gttcataacc ttgaggaagc
    55681 tctccttcta gggcattgat ttgaatcccc tgatgaggga tagctgcttt agataggatt
    55741 tgttccacca atgttttttt gattttaact ttttttgcca ttatttatat ttatcctcca
    55801 attgactcat ccaaatacca agccagattc ccagcgcaaa gaagaaggcg atgatgacat
    55861 aaccgacaag tgaaagtcct gtgtattgga tactttcagc gtttcctgca tttggaatta
    55921 agatcaaaag ggtacttgat aggacgatac cgatgatgaa atgatagacg cgtgagtggt
    55981 agttgtttaa ggcataatcc atcaattttg aaaaaacgat gagagttgca cctgcaccaa
    56041 ttccaatcgg aaagaaggtt cccaagagat caaaagtttt aaaaccagtc aacataggag
    56101 catagagtcc caaaatcaaa agtaaattcg atgggctgag gccaggaacc aagacgccaa
    56161 gggccaatag tgcgcctgct aggacgaagt taagaaagct ggcgcttaag gttccaacga
    56221 caaaatttaa ggcatagagt cctaatccag aaatgataaa ggttgtccat aaccaagcta
    56281 aatcaatctt gtctcggtca gattctcgag ttgattcttt gaggaggcta ggaactgtac
    56341 cgataatagc tcccgcaaag ctccataata caaagacctg ataattttca agcaggtatt
    56401 caatcgggta ggaaaataag ccgattccca gaagcatacc gatggcaact ggaataaagt
    56461 acaaaacatt ttctttaagg tctttaaagg gatgggccag aaagccaatc attcgttcat
    56521 agattcctaa gattgctgct agaacccctc cggaaattcc tggtaggata aatccaagag
    56581 caattacaat ccctttaata acgcgtgcta accatgagag catatatttc ctccaactat
    56641 ttctatttca aaaaatcctt actatattgt atcacaatca gacacaaaaa gaaaaagcaa
    56701 atgataaaca aatgctttta aggttttaaa aaaagttttc gaaaggtttc ttctttattt
    56761 tttaagggag agataacgtt gatatctaaa tcgtggtcaa agccggcaat ttttccttta
    56821 gatgtgtatt ggtgaatatc ataatctaaa tcagttttag gactgctctc caaaaatcct
    56881 gagtctgagc cgtaggacgg aatccaaaca gaggtaaact tgcctgtatc aatactgtgt
    56941 tcttccatga agtagacacc aacgtagatg ccgatgtttt tagcacctag tgatgctagt
    57001 tttgctcgaa agttttcgac accttcgttc atattagaca tggttttgtc ttccacgtca
    57061 agccaatagt aactagggct gtaaggagag gcagcattgt agaaaacttc ggcagccttt
    57121 tccatttctt gggcactttt tccagctaca taagcgtaga cagcaactgg gacattccgc
    57181 ttttgaagtt cagtgatatg actcttatag gccttgtcta ttccattgat aaatgaagca
    57241 tcattttctt ttgtcgtttg agcaccactg tgaacacgaa caatagcacc tgaaatattt
    57301 tgtgagaggg catcgtagtt gatttcctca ggacgctgcc agccagagag gtcaataatc
    57361 ggtttgtcta agtgtttcaa agcctgtgct tcaatctgtg ctatattgga ttttgtttta
    57421 aacgattggc tgtcattaag tgggcgattg atgattaaaa tgaacatcat aatccccaaa
    57481 aaactaaata aaataagtgg atgaatttgt tttctcatat cttataattc taccctaaaa
    57541 atcaaaaaaa atcaaaaaaa tgggttaagg aagagacttt agagcatttt ttcattcaag
    57601 agtgcggaat gatttgaaat atggtataat aaaagggaat ttctacagaa aagagaagat
    57661 tatgtcaaat tttgccatta ttttagcagc gggtaaaggg actcgcatga aatctgattt
    57721 gccaaaagtt ttgcacaagg ttgcgggtat ttctatgttg gaacatgttt tccgtagtgt
    57781 gggagctatc caacctgaaa agacagtaac agttgtagga cacaaggcag aattggttga
    57841 ggaggtcttg gctggacaga cagaatttgt gactcaatct gaacagttgg gaactggtca
    57901 tgcagttatg atgacagagc ctatcttaga aggtttgtca ggacacacct tggtcattgc
    57961 aggagatact cctttaatca ctggtgaaag cttgaaaaac ttgattgatt tccatatcaa
    58021 tcataaaaat gtggccacta tcttgactgc tgaaacggat aatccttttg gctatggacg
    58081 aattgttcgt aatgacaatg ctgaggttct tcgtattgtt gagcagaagg atgctacaga
    58141 ttttgaaaag caaatcaagg aaatcaacac tggaacatac gtctttgaca acgagcgttt
    58201 gtttgaggct ttgaaaaata tcaataccaa taacgctcaa ggcgaatact atattacaga
    58261 cgtcattggt attttccgtg aaactggtga aaaagttggc gcttatactt tgaaagattt
    58321 tgatgaaagt cttggggtaa atgaccgtgt ggcgcttgcg acagctgagt cagttatgcg
    58381 tcgtcgcatc aatcataaac acatggtcaa cggtgttagc tttgtcaatc cagaagcaac
    58441 ttatatcgat attgatgttg agattgctcc ggaagttcaa atcgaagcca atgttacctt
    58501 gaaagggcaa acgaaaattg gtgctgagac tgttttgaca aacggtactt atgtagtgga
    58561 cagcactatc ggagcaggag cggtcattac caattctatg attgaggaaa gtagtgttgc
    58621 agacggtgtg acagtcggtc cttatgctca cattcgtcca aattcaagtc tgggtgccca
    58681 agttcatatt ggtaactttg ttgaggtgaa aggatcttca atcggtgaga ataccaaggc
    58741 tggtcatttg acttatatcg gaaactgtga agtgggaagc aacgttaatt tcggtgctgg
    58801 aactattaca gtcaattatg acggcaaaaa caaatacaag acagtcattg gagacaatgt
    58861 ctttgttggt tcaaattcaa ccattattgc accagtagaa cttggtgaca attccctcgt
    58921 tggtgctggt tcaactatta ctaaagacgt gccagcagat gctattgcta ttggtcgcgg
    58981 tcgtcagatc aataaagacg aatatgcaac acgtcttcct catcatccta agaaccagta
    59041 ggagcctatc atggagtttg aagaaaaaac gcttagccga aaagaaatct atcaaggacc
    59101 aatatttaaa ctggtccaag atcaggttga attaccagaa ggcaagggaa ctgcccaacg
    59161 ggatttgatt ttccacaatg gggctgtctg tgttttagca gtaacggatg aacaaaaact
    59221 tatcttggtc aagcagtacc gcaaagctat cgaggctgtc tcttacgaaa ttccagccgg
    59281 aaaattggaa gtaggagaaa acacagcccc tgtggcagct gcccttcgtg aattagagga
    59341 agaaacagcc tatacaggga aattagaact cttgtacgat ttttattcag ctattggctt
    59401 ttgtaatgag aagttaaaac tatatttagc aagcgatttg acaaaagtgg aaaatccgcg
    59461 tccgcaggat gaggatgaaa ccttggaagt ccttgaagtg agcttagaag aagcgaaaga
    59521 attaatccaa tcaggtcata tttgtgatgc caagacaatt atggctgttc agtattggga
    59581 gttgaagaaa aaatagagga ggtcagtatg ggtaaatctt tattaacgga tgaaatgatt
    59641 gaaagagcta atagaggcga aaaaatttca ggtcctcctt tgctagatga taatgaggag
    59701 actaagattt taccaacctc ttcttcccgt tttggttatg ccaatcctaa gaatcatggt
    59761 tttagccagg aaaccttgaa gattcaggtc gaaccatcta ttcataaaag ccgtcgcatt
    59821 gaaaatacca agagaaatgt cttcaattct aagttgaata aaatcttatt cgcggtcatc
    59881 tttctcttga ttttgcttgt tttagcaatg aaacttttgt aatagaaaag gaattgaaat
    59941 gaaaatagga attattgctg ctatgccaga agaactggct tatctggtcc agcatttaga
    60001 taatgcccag gagcaagttg tttgtgggaa tacctatcat acaggaacca ttgcttctca
    60061 tgaagtcgtt cttgtagaaa gtggaattgg taaggtcatg tctgctatga gtgtggcgat
    60121 tttggctgat catttccagg tggatgccct tattaatacg ggttcagctg gggcagtagc
    60181 agaaggtatc gctgttgggg atgtcgtgat tgctgacaaa ttagcctatc atgacgtgga
    60241 tgtcacagct tttggctatg cttatggaca aatggcgcaa caaccgcttt atttcgaatc
    60301 agacaaaacc tttgttgctc aaatccaaga gagtttatct caattggacc aaaactggca
    60361 tcttggtttg attgctacag gagatagttt tgttgcagga aatgacaaga tagaagcgat
    60421 taagtcccat ttcccagaag ttttagccgt ggagatggag ggggcagcta ttgctcaagc
    60481 agcgcatgcc ctcaatctcc cagtcttagt catcagagct atgagtgaca atgccaacca
    60541 tgaagcaaac atcttttttg atgagtttat tatcgaagct ggacgtcgct ctgcccaagt
    60601 cttgttgacc tttttgaagg ctttagatta agcggaaatt tgacagtttt tctagcttat
    60661 gataagattt aagtaaagaa aagctagaaa acgtttcaga ggatattatg agtattgaaa
    60721 tgaccgtcag tgagattgca gaggtcttag gattatctcg ccaagcaatc aataaccgtg
    60781 tcaaagaatt accagaagaa gacacagata aaaatgacaa aggggtaaca gttgttacca
    60841 gaagtggctt gattaagcta gaagaaatct ataaaaaaac gatttttgaa gatgagcctg
    60901 tcagtgaaga tgtcaaacaa cgtgaactga tggagattct agtggatgag aagaatgcag
    60961 aaattcttcg tctttatgaa caattaaaag ccaaggatcg tcagttatca gaaaaagacg
    61021 agcagatgcg tatcaaagac cgtcagattg ctgagaaaga caaacaatta gatcagcaac
    61081 aacaattgac ccttcaagcc atgaaggatc aagaaaatct taagctagag ctggaccaag
    61141 caaaagaaga agtccaatcc actaagaaag gcttttttgc tcgtttattt ggaggataat
    61201 caaggagctg tttaggttaa atgctaacct gatggcttct tttgtttgtg aatagtatag
    61261 ttgattagaa cagagacagt agaggagagg aacagaatgg aacgattaga agattacatt
    61321 gcttttgact tagaatttaa tcagcacgaa ggacaaacac acttgattca agtatcggca
    61381 gtgcgtttta gagatggtcg ggaaatcgat gcctatgatt cctatgttca taccagcgtc
    61441 cctctaaaaa gctttatcaa tggtttgacc gggattacag ctgagacctt aaaagatgct
    61501 cctccagttg agaaagtctt agaagaattc caagagtttg tgggttcttt gctgatgata
    61561 gactacaatg ctgctaaaag tgatttacct attttagcag agcatggttt agactatagc
    61621 caacagtaca aggtggattt gtatgatgaa gcttttgaac gtcggagttc agatttacat
    61681 ggtattgcca atctcaaatt gcaaactgtt gcctcatttc ttggatttca aggtcagtct
    61741 cataatagtt tagaggatgc tcggatgacg gcgcgtgttt acgaatcctt cttagagtcg
    61801 gatcaagcta gggaattgtt agagacagaa agtagcttat caaacaatcc ttttggtgtc
    61861 ttggacttgt ctcaattatt tgactaggag tgcctatgaa acctgaaaaa cctaaaaaat
    61921 tgggtcttaa acagatttac ctcaatcttg ataaaatcct ctttctattt ttcttgattt
    61981 ttatgatagt ggagtatttg tgggtaccat tcaattcatg gttggctagc ttcttattag
    62041 atcagacagg ttatcttttt atttcctata acaatgtctt agccatcctt actcattctc
    62101 cattgattag tctagctttt ttagccttga ttgtaattaa ccttctggtt gcttattttc
    62161 aaataggact cctctttatt ggtgctcgtc atctcctcta taatgaaaag cgaaggctaa
    62221 ttgagtatat ccgcaaggtt ttccatgaaa gttttggatt tatgaaaaag ctaactggcg
    62281 ctaaagcctt gtttatcttt ttctatatag ctatgctttt tccttttata cggaaaatgc
    62341 tgaagattta ttatcttaat aaaatcgtca ttccagagtt tatccaagct tatttagaag
    62401 ataaatattg gatgtggtgg ctgagcatcc tacttctatc tcttatcttt ctctatgtct
    62461 ctgtcagatt gatgtttgcc cttccgaaga ttgtatatga tcagctgact gttcgagaag
    62521 cagtgatgtt tagcttggag aaaaccaaga agagagttac tttttatgct tggaatttat
    62581 tttacatctt gctcaaagca catttattat tttatcttcc tttgattcct ttattattgg
    62641 ctcaaacttt ggtagatgat atcactcaga gagagtctct gattcttggt attttgaatt
    62701 ttgtcgtgat taaaaatctc tattatatgg ctctgactta ttttttggtt aaatttgttt
    62761 catttttgac aggaaaggag ctggatatgc ttcctaggag agaaaaagat cacatcgtgc
    62821 gatggggtgt cataacttgt gccagtcttt tctttgcctt agaaggttat atttatctgg
    62881 aggctcccat ggttcatcta cctcaactta tttctcaccg aggggtttcc aatgcaaatg
    62941 ggattcaaaa tacagtagag tccttggaaa ctacagcaca actcaaacca gacttggtgg
    63001 agacggacgt gcaggaaaca aaagatgggc agtttgtcat gatgcatgat gctaacttga
    63061 aaaatctagc aggtatcaat aaaagtcctc aagacttaaa cttggaggag cttaaaggga
    63121 ttgatatttt tgaaaatggc taccagacta aaatttcaag ctttgaagat tatctcagtc
    63181 gagccaacga acttggtcaa aaattactaa ttgaaattaa aaccagtaaa aaagatagtc
    63241 cagacatgat gaaccgcttt ttagcccgtt atgctgcaaa gctcaagatt tatggacatc
    63301 aaatccagtc tttagactac catgttgtcg aaaaagtaag acagtatgat gccgaactgc
    63361 cagtttattt catcatgccc tacaattctg tctttcctaa aacaagagcg acaggatata
    63421 ctatggagta ctcaaccttg gatgaatatt ttgtaagcaa actatggaca acggatcaga
    63481 aactttatgt ctggactgtc aatgattcag aagctatcag caaatctctt cacttaggag
    63541 tagatggagt gattacagat gatttggaaa aagttcagcg ggaaatagaa gtagcccaag
    63601 aaaatccaga atatacggat ttgctcttga aaaaagcatt ggaattcttt gaattttagt
    63661 aataaaaaag aggaacggtt gttcctccca tgataggtaa gtattcttgt gaatgcttgc
    63721 ttttttgtgg ttgcaatccg tttacgagaa ttgtttgtat tgttcttgtt tcaatttact
    63781 ttatagtgct ttgaagttgg aatgctacac tataacttct aaaatatagt aaaatgaacc
    63841 aaaaatagta cacaatgtgg tataatcttt ttatggcata ttcaatagat tttcgtaaaa
    63901 aagttctctc ttattgtgaa cgaacaggta gtataacaga agcatcacac gttttccaaa
    63961 tctcacgtaa taccatttat agctggttaa agctaaaaga gaaaacagga gagctaaacc
    64021 accaagtaaa aggaacaaaa ccaagaaaag ttgatagaga tagacttaaa aactatctta
    64081 ctgataatcc agacgcttat ttgactgaaa tagcttctga atttggctgt catccaacta
    64141 ccatccacta tgcactcaaa gctatgggct acactcgaaa aaaagaacca cacctactat
    64201 gaacaagacc cagaaaaagt agccttattt cttaagaatt ttaatagttt aaagcaccta
    64261 gcacaggtct aacaaatggt gaattaatcg ctccaatgac ttacgaagag atgatgacga
    64321 gcgacttttt tgaagtatgg tttcagaagt ttctcttacc aacattaacc acaccatcgg
    64381 ttattatagc gaaatgaaat aagaacagga caaatcgatc aggacagtaa aatcgaattc
    64441 taacaatgtt ttagaagtcc atatgtacta ttctagtttc aatataccat aactgttcct
    64501 agtcaacctg caagtcctgt cccagctcca agctcagctc cgactcaaga tcctagagtg
    64561 gtagcaagcg cttcggctag ctcaacgagc acacaagctc aagagcaagt tgacaagtct
    64621 gaacttcgtg ccttgagtca agagttagac caacgcttga aagctttggc aacagtatct
    64681 gatccgaaaa tcgatgcaac caaggctgtc ctcctagatg ctcaaaaagt tccggaagat
    64741 agtgccttga cagagtaagg tctgcatact gcagtagagt ctgtgaaggc tgccttggac
    64801 tctctcaaag atgtgaaagc aaatgctagc gacagcaagc ctgcacagga caagaaggat
    64861 gcaaaacaag gaacggaaga tagtaaggat tcagataaga tgactgaaac aaactcagtt
    64921 ccggcaggag tgattgtggt cagtctactt gccctcctag gcgtgattgc cttctggctg
    64981 attcgccgta agaaagagtc agaaatccag caattaagca cggaattgat caaggttcta
    65041 ggacagctag atgcagaaaa agcggataaa aaagtccttg ccaaagccca aaaccttctc
    65101 caagaaaccc ttgatttcgt gaaagaagaa aatggcttag cagagacaga aactaaacta
    65161 gtagaggagc ttaaagcaat ccttgacaaa ctcaagtaaa acatgattta tgaaatgtca
    65221 gacctaaaag acattttcgt tcacaaaagc agcgatgagt aatccttgtc gttgcttttt
    65281 ggctattttg ggggataaga tccgccttga ctagcaaaag aaaagattgg tccaatagtg
    65341 cccgatacga ttttgcgtag cagaaagctt acaaataaaa ttgaatatag taaaatagga
    65401 ttagaattat taagaaagtt ggttctttat tggaaacgat agtattttta atctctgttt
    65461 ttctagcagg tgttttatcc tttttttctc cttgtatttt tcctcttctg ccagtctatg
    65521 ctgggatttt attggatgat caagaaagtg caaaaagctt ttctttgttt gggagaaagg
    65581 ttctctggtc aggcttgatt cgaacacttt gctttatcgc tggtatctct ctcattttct
    65641 ttattctagg ctttggtgct ggttactttg gtcatattct ctatgcaaat tggtttcgat
    65701 atggcatggg agctattatt atcattttgg gtcttcacca gatggaaatt tttcatttga
    65761 agaaattaga agttcaaaaa agttttacct ttaaaaaatc agattctaat cgttattggt
    65821 cagctttttt acttggtatt acctttagct ttggttggac accttgtatt ggtccagttt
    65881 taagttctgt tttagcactt gcggcttctg gaggcaatgg cgcttggcaa ggagcgattt
    65941 atactctcat ttacactctg ggcatggccc ttcctttctt ggtattggca ctagcttcag
    66001 gtctagtcat gccatatttt agtaaaatca agcgtcatat gatgctacta aagaaaattg
    66061 gtggtttcct cattgtttta atgggaattt tgttactatt aggacaagta aatgttctag
    66121 ctggaatttt tgaataaagg aggacaaatg aaaaaagtaa tgtttgctgg cttaagtctc
    66181 ttgtcattag ttgtattgat ggcctgtggt gaggaagaaa ctaaaaagac tcaagcagca
    66241 caacagccaa aacaacaaac gactgtacaa caaattgctg ttggaaaaga tgctccagac
    66301 ttcacattgc aatccatgga tggcaaagaa gttaagttat ctgattttaa gggtaaaaag
    66361 gtttacttga agttttgggc ttcatggtgt ggtccatgca agaaaagtat gccagagttg
    66421 atggaactag cggcgaaacc agatcgtgat ttcgaaattc ttactgtcat tgcaccagga
    66481 attcaaggtg aaaaaactgt tgagcaattc ccacaatggt tccaggaaca aggatataag
    66541 gatatcccag ttctttatga taccaaagca accaccttcc aagcttatca aattcgaagc
    66601 attcctacag aatatttaat tgatagccaa ggaaagattg gaaagattca atttggtgct
    66661 atcagtaatg cggatgcaga agcagcattt aaagaaatga actagaatcg ataaaatctg
    66721 attacaagat gtagtcagat tttggtaact tctaaaacta acttccagtt tcccacaacc
    66781 tagcttttag tatgagaaaa acgcgtgaca tcagtggaaa tccgtcttag actaacttcc
    66841 actggttttc tttttcttga tatataaggg ttcaaaagcg aaaagactca gaaaaagtgc
    66901 acgacaaata gccctaaaac agagtcgtct tagagtaact tccagttttg ggagagagat
    66961 ggaagttact ttgagaagtt acggtagtca gattttttta gaaaaacatt ttataaatat
    67021 tcacatatct cctatattta tggtaaaata gaattatcag tttattttgg agtcaaagat
    67081 gaatatattt agaacaaaga atgttagttt agataaaaca gagatgcata ggcatttgaa
    67141 gttatgggat ttgattttgc tgggtatcgg agccatggta gggacaggcg tctttacaat
    67201 cacaggtact gcagctgcaa cacttgctgg cccagcccta gtgatttcaa tcgttatttc
    67261 tgccttgtgt gtgggattat cagccctctt ttttgcagaa tttgcctcgc gagtacccgc
    67321 tacaggaggt gcctatagtt acctctatgc tatcttagga gaattccctg cctggttggc
    67381 tggttggtta accatgatgg agttcatgac agccatatca ggcgtagctt cgggttgggc
    67441 agcttatttt aaaggcttgc tctctcaata cgggatagcc tttcctcagg ctttaaatgg
    67501 tacctttaat cctcaagcag ggacatttgt tgatttattg cctattcttg tcttggtctt
    67561 ggtgacttcg cttgttttac taaatgccaa ggcagcctta cgctttaatt cgattctagt
    67621 tattttgaaa ttttccgctt tagctctctt tgttttagta ggaatttgga atattaagtt
    67681 tgataattgg agcaattttg ctccttacgg ttttggacaa atctatggag ctagcactgg
    67741 tattatggct ggtgcgtcct tgatgttctt cggttttttg ggatttgaat ccatctctat
    67801 ggctgtagat gaagtcaaga ctcctcaaaa aaatattcct agagggattg tcttatcgct
    67861 ttctatcgta accattctct atgccttggt gacccttgtt ttgactggtg tggttcacta
    67921 tagtcattta aatgtcgatg atgccgttgc ctttgccctt cgtagtgttg ggattagttg
    67981 ggcagccaac tatgtgtcat tagtggctat cttgaccttg attacagttt gtatttcgat
    68041 gacctatgcc ctatcgcgta tgatttacag tttagcacgt gacggcttag tgcctgctgc
    68101 ctttaaggaa ctgacgaaga ctagcaagat accaaagaat gctactatct tgacaggtct
    68161 agcttcagca gtagcagcag gaatgttccc actagccagt attgcagcct ttttaaatat
    68221 ttgtacctta gcctacttga tcatgttggc ttatggtctg attcgcttac ggaaagaaaa
    68281 aggaatgccc aaagctgggg aatttaaaac accattggta cctctgttac caattttatc
    68341 gatcatcatt tgtttatcct tcatgttaca gtataatatg aatacctgga ttgctttcct
    68401 agttgcgttg ttagtaggaa gtattattta cttcacttat ggctataagc attctaccat
    68461 agaagaataa agtgaaagtc tattgagttg ttgacactca gcagattttt atatgtgaaa
    68521 gaaatttcaa attttttcta aaaatatctt gacagattaa attttcagga gtagaatatt
    68581 tactagttaa ttaaatggtt aaggagttgt tcatgaagaa acaaaattta tttttagtcc
    68641 tgttaagtgt ctttcttttg tgcttggggg cttgtggtca aaaggaaagt cagacaggaa
    68701 aggggatgaa aattgtgacc agtttttatc ctatctacgc tatggttaag gaagtatctg
    68761 gtgacttgaa tgatgttcgg atgattcagt caagtagtgg tattcactcc tttgaacctt
    68821 cggcaaatga tatcgcagcc atctatgatg cagatgtctt tgtttaccat tctcatacac
    68881 tcgaatcttg ggcaggaagt ctggatccaa atctaaaaaa atccaaagtg aaggtcttag
    68941 aggcttctga gggaatgacc ttggaacgtg tccctggact agaggatgtg gaagcagggg
    69001 atggagttga tgaaaaaacg ctctatgacc ctcacacatg gctagatcct gaaaaagctg
    69061 gagaagaagc ccaaattatc gctgataaac tttcagaggt ggatagtgag cataaagaga
    69121 cttatcaaaa aaatgcgcaa gcctttatca aaaaagctca ggaattgact aagaaattcc
    69181 aaccaaaatt tgaaaaagcg actcagaaaa catttgtaac acaacataca gccttttctt
    69241 atctagcgaa gagatttggg cttaatcaac ttggtattgc aggcatctct cctgaacaag
    69301 aaccaagtcc acgacaatta acagaaattc aggaatttgt taaaacctat aaggttaaaa
    69361 cgatttttac agaaagtaat gcttcttcaa aagtagctga aactcttgtc aaatcaacag
    69421 gtgtgggtct taaaactctg aatcctttag aggcagaccc acaaaatgac aagacctatt
    69481 tagaaaatct ggaagaaaat atgagtattc tagcagaaga attaaagtga ggaaagaatg
    69541 aaaatcaata aaaaatatct agcaggttca gtggcagtcc ttgccctaag tgtttgttcc
    69601 tatgaacttg gtcgtcacca agctggtcag gttaagaaag agtctaatcg agtttcttat
    69661 atagatggtg atcaggctgg tcaaaaggca gaaaatttga caccagatga agtcagtaag
    69721 agagagggga tcaacgccga acaaatcgt
//
LOCUS       DAVLDI010000003        55109 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLDI010000003 DAVLDI010000000
VERSION     DAVLDI010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55109
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.003"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(227..1789)
                     /gene="guaA"
                     /locus_tag="VXD01_000178"
     CDS             complement(227..1789)
                     /gene="guaA"
                     /locus_tag="VXD01_000178"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV0600642.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            1931..2629
                     /locus_tag="VXD01_000179"
     CDS             1931..2629
                     /locus_tag="VXD01_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0600643.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(2672..3568)
                     /locus_tag="VXD01_000180"
     CDS             complement(2672..3568)
                     /locus_tag="VXD01_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0600644.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLSYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQANIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(3577..4512)
                     /locus_tag="VXD01_000181"
     CDS             complement(3577..4512)
                     /locus_tag="VXD01_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV0600645.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYSGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQTFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4509..5234)
                     /locus_tag="VXD01_000182"
     CDS             complement(4509..5234)
                     /locus_tag="VXD01_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV0600646.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(5318..5953)
                     /locus_tag="VXD01_000183"
     CDS             complement(5318..5953)
                     /locus_tag="VXD01_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV0600647.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKMIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQDL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(5955..6782)
                     /locus_tag="VXD01_000184"
     CDS             complement(5955..6782)
                     /locus_tag="VXD01_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0600648.1"
                     /translation="MMIKIIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(6804..7139)
                     /locus_tag="VXD01_000185"
     CDS             complement(6804..7139)
                     /locus_tag="VXD01_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEV0600649.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEGGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7140..7856)
                     /locus_tag="VXD01_000186"
     CDS             complement(7140..7856)
                     /locus_tag="VXD01_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEV0600650.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPAEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEQRDQAPLVIKEVNGIKVALLAYSYGFNGIEQYISQEDYNRYLLD
                     LNEDKMKAEVERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIIY"
     gene            8369..8980
                     /locus_tag="VXD01_000187"
     CDS             8369..8980
                     /locus_tag="VXD01_000187"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0600651.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9025..9753
                     /gene="rlmB"
                     /locus_tag="VXD01_000188"
     CDS             9025..9753
                     /gene="rlmB"
                     /locus_tag="VXD01_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV0600652.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKNEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(9792..10703)
                     /gene="trxB"
                     /locus_tag="VXD01_000189"
     CDS             complement(9792..10703)
                     /gene="trxB"
                     /locus_tag="VXD01_000189"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV0600653.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQVFGGVFIYVGLDPLGDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(10769..10993)
                     /locus_tag="VXD01_000190"
     CDS             complement(10769..10993)
                     /locus_tag="VXD01_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV0600654.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11071..11814)
                     /locus_tag="VXD01_000191"
     CDS             complement(11071..11814)
                     /locus_tag="VXD01_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0600655.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(11814..12614)
                     /locus_tag="VXD01_000192"
     CDS             complement(11814..12614)
                     /locus_tag="VXD01_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0600656.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(12772..13128)
                     /locus_tag="VXD01_000193"
     CDS             complement(12772..13128)
                     /locus_tag="VXD01_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0600657.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13122..13652)
                     /locus_tag="VXD01_000194"
     CDS             complement(13122..13652)
                     /locus_tag="VXD01_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV0600658.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(13652..14146)
                     /locus_tag="VXD01_000195"
     CDS             complement(13652..14146)
                     /locus_tag="VXD01_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0600659.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14281..14727
                     /locus_tag="VXD01_000196"
     CDS             14281..14727
                     /locus_tag="VXD01_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV0600660.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            14724..15371
                     /locus_tag="VXD01_000197"
     CDS             14724..15371
                     /locus_tag="VXD01_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV0600661.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(15392..15973)
                     /gene="pdxT"
                     /locus_tag="VXD01_000198"
     CDS             complement(15392..15973)
                     /gene="pdxT"
                     /locus_tag="VXD01_000198"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV0600662.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(15974..16849)
                     /gene="pdxS"
                     /locus_tag="VXD01_000199"
     CDS             complement(15974..16849)
                     /gene="pdxS"
                     /locus_tag="VXD01_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV0600663.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17001..18380)
                     /locus_tag="VXD01_000200"
     CDS             complement(17001..18380)
                     /locus_tag="VXD01_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0600664.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAER"
     gene            18674..19597
                     /locus_tag="VXD01_000201"
     CDS             18674..19597
                     /locus_tag="VXD01_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV0600665.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            19657..20262
                     /locus_tag="VXD01_000202"
     CDS             19657..20262
                     /locus_tag="VXD01_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0600666.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEETDGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20281..21525
                     /locus_tag="VXD01_000203"
     CDS             20281..21525
                     /locus_tag="VXD01_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0600667.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISVSLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGNADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(21641..21898)
                     /locus_tag="VXD01_000204"
     CDS             complement(21641..21898)
                     /locus_tag="VXD01_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV0600668.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEKGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(21940..23976)
                     /locus_tag="VXD01_000205"
     CDS             complement(21940..23976)
                     /locus_tag="VXD01_000205"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV0600669.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLILSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24200..25117)
                     /gene="glyQ"
                     /locus_tag="VXD01_000206"
     CDS             complement(24200..25117)
                     /gene="glyQ"
                     /locus_tag="VXD01_000206"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV0600670.1"
                     /translation="MSKKLTFQEIILTLQRFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(25311..26072)
                     /locus_tag="VXD01_000207"
     CDS             complement(25311..26072)
                     /locus_tag="VXD01_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0600671.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(26345..27187)
                     /locus_tag="VXD01_000208"
     CDS             complement(26345..27187)
                     /locus_tag="VXD01_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV0600672.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSITTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(27301..28692)
                     /locus_tag="VXD01_000209"
     CDS             complement(27301..28692)
                     /locus_tag="VXD01_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV0600673.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(28927..29304)
                     /locus_tag="VXD01_000210"
     CDS             complement(28927..29304)
                     /locus_tag="VXD01_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0600674.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKICQREGDTHQSYKHIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            29537..30514
                     /locus_tag="VXD01_000211"
     CDS             29537..30514
                     /locus_tag="VXD01_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0600675.1"
                     /translation="MLKLGVIGTGAISHHFIEASHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            30511..31593
                     /locus_tag="VXD01_000212"
     CDS             30511..31593
                     /locus_tag="VXD01_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0600676.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSKT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLIYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(31657..32703)
                     /locus_tag="VXD01_000213"
                     /pseudo
     CDS             complement(31657..32703)
                     /locus_tag="VXD01_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(33087..34283)
                     /gene="tuf"
                     /locus_tag="VXD01_000214"
     CDS             complement(33087..34283)
                     /gene="tuf"
                     /locus_tag="VXD01_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV0600677.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(35194..36063)
                     /locus_tag="VXD01_000215"
     CDS             complement(35194..36063)
                     /locus_tag="VXD01_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0600678.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(36287..36964)
                     /locus_tag="VXD01_000216"
     CDS             complement(36287..36964)
                     /locus_tag="VXD01_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0600679.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEP
                     TPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLASLVLGFF
                     KKKEDEK"
     gene            complement(36922..38001)
                     /locus_tag="VXD01_000217"
     CDS             complement(36922..38001)
                     /locus_tag="VXD01_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV0600680.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDIVEPSRTVVEKIIPKLNIPEEEKKKKTSELAE
                     LISENVKVCYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNVTDKKLSSMT
                     TTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKEGSQEKL
                     AESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAYQKTVQQ
                     LTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(38112..38366)
                     /locus_tag="VXD01_000218"
     CDS             complement(38112..38366)
                     /locus_tag="VXD01_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600681.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPIWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(38706..39239)
                     /locus_tag="VXD01_000219"
     CDS             complement(38706..39239)
                     /locus_tag="VXD01_000219"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0600682.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKNLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(39226..39441)
                     /locus_tag="VXD01_000220"
     CDS             complement(39226..39441)
                     /locus_tag="VXD01_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0600683.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(39408..39551)
                     /locus_tag="VXD01_000221"
     CDS             complement(39408..39551)
                     /locus_tag="VXD01_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEV0600684.1"
                     /translation="MAYSTDFKQRALDYIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            39785..41503
                     /locus_tag="VXD01_000222"
     CDS             39785..41503
                     /locus_tag="VXD01_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV0600685.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNETAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            41614..41961
                     /locus_tag="VXD01_000223"
     CDS             41614..41961
                     /locus_tag="VXD01_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0600686.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     ADTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(42239..43075)
                     /locus_tag="VXD01_000224"
     CDS             complement(42239..43075)
                     /locus_tag="VXD01_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0600687.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(43088..43717)
                     /locus_tag="VXD01_000225"
     CDS             complement(43088..43717)
                     /locus_tag="VXD01_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0600688.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(43727..44368)
                     /locus_tag="VXD01_000226"
     CDS             complement(43727..44368)
                     /locus_tag="VXD01_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0600689.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(44514..45743)
                     /locus_tag="VXD01_000227"
     CDS             complement(44514..45743)
                     /locus_tag="VXD01_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV0600690.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(45733..46899)
                     /locus_tag="VXD01_000228"
     CDS             complement(45733..46899)
                     /locus_tag="VXD01_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0600691.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            47043..48056
                     /locus_tag="VXD01_000229"
     CDS             47043..48056
                     /locus_tag="VXD01_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV0600692.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(48101..48520)
                     /locus_tag="VXD01_000230"
     CDS             complement(48101..48520)
                     /locus_tag="VXD01_000230"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV0600693.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(48531..49937)
                     /gene="atpD"
                     /locus_tag="VXD01_000231"
     CDS             complement(48531..49937)
                     /gene="atpD"
                     /locus_tag="VXD01_000231"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV0600694.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(50023..50901)
                     /locus_tag="VXD01_000232"
     CDS             complement(50023..50901)
                     /locus_tag="VXD01_000232"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV0600695.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(50917..52422)
                     /locus_tag="VXD01_000233"
     CDS             complement(50917..52422)
                     /locus_tag="VXD01_000233"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV0600696.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(52437..52973)
                     /locus_tag="VXD01_000234"
     CDS             complement(52437..52973)
                     /locus_tag="VXD01_000234"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV0600697.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(52973..53467)
                     /gene="atpF"
                     /locus_tag="VXD01_000235"
     CDS             complement(52973..53467)
                     /gene="atpF"
                     /locus_tag="VXD01_000235"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV0600698.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(53481..54197)
                     /gene="atpB"
                     /locus_tag="VXD01_000236"
     CDS             complement(53481..54197)
                     /gene="atpB"
                     /locus_tag="VXD01_000236"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV0600699.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLPYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(54232..54432)
                     /locus_tag="VXD01_000237"
     CDS             complement(54232..54432)
                     /locus_tag="VXD01_000237"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV0600700.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(54507..>55109)
                     /locus_tag="VXD01_000238"
     CDS             complement(54507..>55109)
                     /locus_tag="VXD01_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0600701.1"
                     /translation="QDLLYPRKGKALKKQASTNFKPAGQSIEQRSEAINLRLENGHYE
                     IDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVNQALKLILKQHKILSITADN
                     GTEFNRLFDVFSEEHIYYAHPYAFWERGTNENHNRFIRRWLPKGTKKMTPKEVAFIEK
                     WINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRFQ"
BASE COUNT        16343 a        12131 c         9980 g        16655 t
ORIGIN      
        1 ctccaaaaaa cttgattttg gagtagttat aaaaactcat tcagataatt tattatttga
       61 ttttgatacg attcctgaaa atataatagt agttgaccat tttgaactta caatcgaaaa
      121 atggttaagt aaaagtcaac agttactata gtttgcaaat tatttacaga aagaacaaaa
      181 aatgctctga aacactgatt tcaaagcatt ttttgttagt ttaaaattac tcccactcaa
      241 ctgttgcagg tggtttactt gtaatatcgt agacgatacg gttaacatga tccacttcat
      301 ttacgatacg tactgagatt ttttgaagta cttcccatgg aattttggca aaatcagcag
      361 tcataccatc gatagaagtg atagcacgga ttgcaatcgt gtagtcatac gtacgaccgt
      421 cacccataac accgactgaa cgaacgcctg tgttaacagt gaagtattgc caaatatcgc
      481 ggtcaagtcc agctttagcg atttcttcac gaagaatagc gtctgattca cgaacggttt
      541 caagtttctc ttcagtgatt tcacccatga cacggatagc aagtcctggt cctgggaatg
      601 gttggcgcca tacgatatgg tctggcatac caagctctgt accaagagca cgaacttcat
      661 ccttgtaaag agtattaagt ggttcaatca attcaaactg catatcttct ggaagaccac
      721 ccacgttgtg gtgtgacttg atagtttgag ctgtatccgt accagactcg ataacatctg
      781 tgtataaagt accttgagca aggaatttca catctttgag cttgcttgct tcgtcatcga
      841 atacatagac aaactcgtta ccgatgattt tacgtttttg ttcaggatca gaaacgccag
      901 caagtttgtc aaggaaacgt ttagcagcgt ctgctttgac gatattcaaa ccaaacttac
      961 caccgagcat gtccataact tgatcagctt cgcctttacg aagaagaccg tggtctacga
     1021 agatacagat caattgatcg ccaatcgctt tttggagaag aaccccaacg acagatgagt
     1081 caacaccacc tgatagacca agaaggacac gtttatcacc gacggtttca cgaatttttt
     1141 tgatctgcat gtcaatgaaa ttatccattg accagtcacc tttagcctta caaatgttaa
     1201 gggcaaagtt acgaaggata tcatttccgt atacagaatg acgaacttct gggtggaatt
     1261 ggataccgta aatgtgttta tctgggtttt cgatggctgc gtatgggcag tcagctgatg
     1321 tacctgtacg aacaaagtca gcaggaatct cagtaaccgc atcaccatgg ctcatcaaaa
     1381 cagtctgttc atcaggtgtt gattcaaaaa gcgctgatgg tgtgtgagtt agggttgatt
     1441 gaccgtattc acgatttcca gcatcacctg caggaacaac ttttcctcca agtttatggg
     1501 tcaataactg cataccataa cagattccca aaattggaat tccgagttcg aagatttctg
     1561 ggtcaatatc aaatgaacca tcttcatata cagaatttgg accacctgat agaataattc
     1621 ctacaggatt gacttcacga acttcagcag ctgaaatttt atggcttttt agttctgaaa
     1681 aaacaccaat ctcacggata cggcgtgaaa tcagctggtt gtactggcta ccatagtcca
     1741 atacgatgat tttttctaca tcttgcaaat cagttgaaat gttgctcatc tttttccttt
     1801 ctcaaaagaa atatcttttc tcaatattct atcacaaata agggcgaatt accaactaaa
     1861 caaggcgaag tttgactttt tctagtttat tggggtacaa tagagaaaag atagaaatga
     1921 agtgaaaaat atgctacctg cttatatgaa aatccatgat cagataaaaa aggatattga
     1981 cgagcaccgt tgggctattg gtgagaggct tcccagtgaa agagatttag ctgagcagtt
     2041 tgcggtcagt cgcatgaccc tccgccaagc cgtatctcta ttagtcgaag aaggcgtctt
     2101 agagcgccgt gtaggaagcg gcacctttgt ttccagtact cgagtacaag aaaagatgcg
     2161 agggacaacc agttttactg aaattgtcaa atcccaaggt aaagttccct ctagccagct
     2221 catttcctac aaaaaaacca ttcccaatga gcaagaagtt gccaagctag gaatttttcc
     2281 aacggacaat attatccgaa tggagcgggt ccgctatgcc gaccaagttc ccctagttta
     2341 tgaagttgct tctattcctg aaaaattcat taaggacttt aaaaaagaag aaatcaccag
     2401 tcatttcttc caaaccttgc agaaacatgg ctatcgtatc ggcaaatctc aacagaccat
     2461 ctatgctcgc cttgctaaag aaaagattgc ccactatttg gaagttgaaa aaggacatgc
     2521 tattcttgga ttgacacagg tttcctacct agaagatggt actgcttttg aatacgtaaa
     2581 aagtcaatat gtaggcgaac gctttgaatt ttatcttgaa aataattaga ttaccacgca
     2641 aaaactctct gtcacagaca aagagtcttt tttatttttc taagaataaa tctttcaaag
     2701 aaatcaaagt tacagcaaac aatatcattg ccataccaag aaaatcaatg ggataaaatt
     2761 gttcattcat tattaagaag gcaaagaaaa ccgccgatat tggctcaatt gaagccaaca
     2821 agcttgactt gaccggtcct atcagactgg ctcctttaag gaaagctgta taggcaaaga
     2881 cagtcccgat aaggataatg cctgcaaacg caaggagaaa atcaagacta gtcgggatat
     2941 tggcctgtag aacccctgta aaaggaaggg cgaccaaacc tgctataacc attcccacac
     3001 caatgaccaa gctactcccc cactttttaa tcaaggctat gggtaaaatg atatatagag
     3061 cataagtcaa ggcagaaaag agaccccaga acaggccagc aggtgtcatg gataactggt
     3121 ccaactgccc atgtgttgcg atcaggaagg ttcctccgat ggcgaatatg atggaaacta
     3181 tctctcccag tgtcggtgcc accctatcct tgatacagct ataaattaaa attccgacag
     3241 gacaaacata ctgaagcacc gtcgctgttc ccgcattggt ctcctgaata gcagacagat
     3301 aggcgaattg gttgagaaaa agaccaatca gagcaaaaat aagaagagac agcaaactct
     3361 ttctatcctt taaaaagacc agtattttat cctttgcagt agcataagac aagagcatga
     3421 gaattccacc agcgattaaa agacgcaagt tggtcaagac cagagccgaa attccgtgtg
     3481 ccattaggta ttggccactc gttcctgaca acccccaagc aataccagcc acaactgtta
     3541 gtaaagtccc ttttaaacta tttgacatgt ctctccttac tcttctttgc gaatcaagtt
     3601 catcacttga ttgcggtcta atatccattg agctctctcg tccttttcat aggtacgatt
     3661 cgataggaaa atagtggctt cttgcttctg acgattccac atgataaagg tacctgtata
     3721 gcccgtatgg tctagccaat ctccttccaa attccatgct aaagaacgtt ccttgtcatc
     3781 caaaggagaa aaattttgat ttaagtctct tgcaaaatca tctgctaaat agtgttctaa
     3841 aaaggtttgt aaatccttta tagtcgaaaa taaaccagca ctcccagcat gtctacccag
     3901 gagacgagcc ttgggatcat gcactatgcc tgcctctaca cctctaactg ttggaacagc
     3961 aagctcaact ggcccaaact tagtttccgt cattccccaa ggtttccaga cttgatcctt
     4021 taaaatcaca tccaaatctt gattaaaaat tctttccaaa ataaagccca acagcaaaaa
     4081 atggacatcc gaataaagaa aggctggctg acttcgtctg ttgagatgaa acatcgcttc
     4141 ctttaattca ggggctgtta aaagatcacg attaggaata aaaggatcaa ggtctgttgc
     4201 atgagtcaag agctggcgaa tagtgatgtc tggataatca ctctcaggta aaaaatctat
     4261 taccagtcta tcaatatcta attgacctat ttcccacaag aaggtacaaa ctgtgccaac
     4321 cccaacaacc ttactgacac tagctaggtc ataaactagt cctgcctcag tctgcaagcc
     4381 atgctctggg tcactctggc ctgaatagaa ctctgtccat tgattgtcct taaaatacgc
     4441 aaaagaggct ccgggataaa tccctgcctc gatttgttct tctatttttt taataatctt
     4501 ggtccacttc atacttcttc aaaccacaat tcaacattat ttctatcttt accaaggaag
     4561 aatttttcag acttaggaat aaaatattca gtagactcaa acttctggcg aagacttgct
     4621 atgtctaatt cattgaccaa gaacttgagc atagataagt cccaggtaac cgtattgtcc
     4681 acagtcaaat cctgcccctg agctggaata aaatcaaggg atgccccaat ttcagatgat
     4741 tccaagaaac tttcgatatc agttgggaga tgtaattcca tagaaatctc aaatttactt
     4801 aaagaaattg atgccaaatc tgtttgaaat tcaggctttt ctcctacttc tactagactt
     4861 gctctgtcat cttccgcatg aatcaaaatc aaatcatctt ctggtgagaa aatttcaaaa
     4921 gcgtagccat tttgaccttt atataatcga tgaatcgaat ctgttttaga taagattcct
     4981 tcaatttcta agggattttc caccttgaca atcaatctag ctagtttttt tcttccctct
     5041 accttacgag tacgcatact gggagcttct tctaaaacca gcttttcaag acccgtttgg
     5101 tcacctagtg acagaaaggc cgattcttct aacaaggcct tcattccaag ggtttcaata
     5161 taaaatgttt catttaattt tctattatta gcttttaaag taggaataat ccgtacaatc
     5221 tgatttacat tcataaattc ctccgtcact ttttatttta aaggatttta gaatttttta
     5281 caagatatta tgctcaaatt tcacattatt tagctattta gtaaagatag tctttcaagg
     5341 cttttgacaa agcctgataa ccagcaatac tgaggtgcag tccatcagtt gtatattctt
     5401 ttttgagttg gcctgcttgg tctgtcaaac aatcaaatac tggcacaaat tccacctgca
     5461 tataggcaga tgcaagatct tgataggctt gattccagtt ctgaattttt tcattcgagc
     5521 ggatatagac tgcctgctga tactcctctc cctcattgac aggtaaaatg gaaagcaatt
     5581 taatctctgt caatggataa tcgcgagcaa cggattgaat gatagcttcg agattattga
     5641 gagcctcatt cacaggaaca tcctttccga tatcatttgt cccaatcaga agaaaaattt
     5701 tatctactgc tccaccatat agatgagcat caaggttctc tagtaacagt cctgtctgat
     5761 agccacgaat tcctcgattg acaatcattt ttgaagtccc aaatagctcc tgtagaggat
     5821 aatactcgac aatggaatcc ccaataaaaa gaatgtttgg ttctacaaca gaaatgtgat
     5881 ttaggtgacg atacttggtt tgaatttttt cttgttcctt taggagccaa ttttctaata
     5941 actgtactgc cacttcattc tcctttttct aaccagtttt ccaagacttg ataaactcct
     6001 ccttggctat tggctggtgc tagagcagtc gccacagctt tggctttctc atcagcattt
     6061 tccatcgcat aggcaattcc agccatttca agcatttcaa catcattttc actatcacca
     6121 aaagccatga tttcttggga tttcaagtcc cagcgcttga gtaattcctc caagccccat
     6181 gctttatgaa tcccagcttg gaggatatca atgcaaccat agccactgga tacagctcgg
     6241 acacggccat caaagagagc attgatttct tccaaaaccg aactcaaacg ttcctcacca
     6301 acaaccatgc tcatcttgag cacaccacca aagaggtcag atgttaattc atccacaaat
     6361 tgcatccgtt ggtagaattt ttcaatcatt tctggagtca taaaactttc aagatctgta
     6421 aaaatcgtac cttccttgac aaaatcaccc ttcatccccg ttacaacaaa ctggtcctga
     6481 cacgctcgac ccttgaaatg agccaaagcc ttgttgacaa tggcgtcatc ccatgtctga
     6541 gcctgaatca attcattgtt ttcaaaaata cgagcgccat tagcaacaac cagaaccact
     6601 cgatccacca agggactcag tagttgtctc atgcggtgaa tttcattgcc cgtcgcaatg
     6661 acaaaacgaa tgcccctttg atccaactga tctaaaatct tttccaatcg tgggagatca
     6721 agctgacctc tagcatccag caaggtccca tccatatctg tcgcaattat cttaatcatc
     6781 atttactttc ctctggattc aagctaatac cacttcaatc ccacatgttc attcatttct
     6841 ttataggctg tatcaattcg ttccttagtc gcttcatcta actggtcacg atgactgcca
     6901 ccctctataa aatcttccaa aatataagtt tggtaatgat acaagggata tccttctggt
     6961 gaaaaggttc cctttggtgt tcgattgacc caagtaggat gagctttagc tgttccgata
     7021 gttgtttttc catccttctt cttgatggtg acatccatga gaacaccacg ttcagtccac
     7081 ttagcattct cttcatctcc catagattca atccgttgat tggaaatgaa gttccccatt
     7141 taatagataa tgagtttctt atctccatct ttttcaaccg tttcagatgg ttcaacaacg
     7201 tgaggatgcc ctccaaagat aatatccgct ccccaatcga tcatcttgtg ataaagagct
     7261 ttttgttctt cagttggttc caatcgatac tcaacaccca tctgaagcat gataatggtg
     7321 atatctgctt ccttctctgc ccgttcaact tcagccttca tcttatcttc gtttaaatct
     7381 aaaagataac gattatagtc ttcctgagaa atatactgct caattccatt gaaaccatag
     7441 gaataggcta acaatgcaac cttgatacca ttcacttcct taatgaccag cggagcctga
     7501 tcacgttgtt cgtgcgtata aactccgatt ggagtgattc cagctttctc aataatatcg
     7561 gccgttgaaa taactccctc aatttgcgaa tccaaaatat gattatgagc taaatccagc
     7621 acatgataac ctgcttcctt aatagcatcc ataacttcag caggagcatt aaagagaaga
     7681 taacccgcta aataatgatc cttattaatg gttccttcga aatcaccaat agctaaatct
     7741 gcttgcttga gccaaggagt cacatactca aaattttcat gaaagtcata ggtaccgtct
     7801 tcttttttag ctgaaaagaa aagtccatcg tggtagagca aatccccgtg ggccataatt
     7861 ctggcagttt tttcctcttc ctactcctga gacttttgct tagtcccctc ttgagaaata
     7921 gtatctcgtt tttgactagt caagggattc cttggaagct ttcaaacaac aagaccaagc
     7981 ccattgataa accaactgct agcaagagta tcgccacaaa tcccttattg ctccacttgc
     8041 gataactcct aaaaagttta ccaagccctt cataaaacga aaagctaaac caccctgatt
     8101 tcgattttgt cttctttgta tcttcgttct ccctactttc ttatgcaagc cttttctttt
     8161 tattatatca cagataagta tttctttcac aattgaattg aacttcctat ctattttcta
     8221 taaatcctaa atgccataat gctttcaatt cttgtcattt tgtgatatca tgtagaggaa
     8281 atgaactaat ccacagtggc ttattccaag tataccactt gggctttggc agtagctaac
     8341 tgcactaaac ataatataag gagagaaaat gtctgcaata gaacgtatta caaaagctgc
     8401 tcacttaatt gatatgaacg atattatccg tgaagggaat cctactctac gcgcgattgc
     8461 tgaggaagtc actttccccc tatctgacca ggaaatcatc ctaggcgaaa agatgatgca
     8521 attccttaaa cattcccaag atcctgtcat ggctgaaaaa atgggactcc gcggtggtgt
     8581 tggactggct gctccccagt tagatatctc aaaacgcatt atcgctgttt tggtacctaa
     8641 tattgttgaa gaaggcgaaa ctccacagga agcctacgat ttggaagcca ttatgtacaa
     8701 tccaaaaatc gtctctcact ctgttcaaga tgctgctctt ggcgaaggag aaggttgcct
     8761 gtctgttgac cgtaacgtgc ctggctatgt tgttcgccat gcccgcgtta ctgttgacta
     8821 ctttgacaaa gatggagaaa aacaccgtat caaactcaaa ggctacaact ccattgttgt
     8881 tcagcatgaa attgaccaca ttaacggtat catgttttac gatcgcatca atgaaaaaga
     8941 cccatttgca gttaaagatg gtttactgat tcttgaataa agaaaatccc gttgcaagac
     9001 ggggttttgt gttataatag aggcatgaaa acaaatgata ttgtctatgg cgtccacgcc
     9061 gttaccgaag ccctccttgc aaatacagga aacaaactct acctccaaga agatctccga
     9121 ggtaagaatg ttgagaaagt caaggaacta gctacagaaa agaaggtgtc catttcttgg
     9181 acatcaaaaa aatctctctc tgagattact gaaggtgctg ttcatcaagg ttttgttcta
     9241 cgagtgtctg aatttgccta tagcgagcta gattacatcc ttgcaaaaac acgccaagaa
     9301 gaaaatccac ttctattgat tctagatggt ctaaccgatc cccataatct aggttctatc
     9361 ttgcgaacag ccgatgcgac caatgtttca ggtgtcatca ttcccaagca ccgtgctgtc
     9421 ggagtaactc ctgtcgttgc caaaacagcc acaggtgcta ttgaacacgt tccaattgcc
     9481 cgagtgacca acctcagtca aaccttagat aaacttaaga atgaaggttt ctggaccttt
     9541 ggaacggata tgaacggtac tccttgccac aagtggaata caaaagggaa aatcgccctc
     9601 atcattggaa atgaaggaaa aggtatctct agcaacataa aaaaacaggt cgatgaaatg
     9661 attaccattc cgatgaatgg acatgttcaa agccttaatg ccagtgttgc tgcggccatt
     9721 ctcatgtacg aagttttccg aaatagacta taaaaaagtt tccagtcatc tgattggaaa
     9781 cttttttatg attaactatg ttctgtaatg aatttatagg cttcttgacc agcgatagct
     9841 ccatctccaa ccgctgttgt tacttggcga aggtctttca agcgaacatc tccaactgca
     9901 aagataccgt cgactgcagt tttcatgtgg ttatctgtca caatccatcc tgcctgatct
     9961 tggatattca attctttaac aaaatcgcca agagggtcca atccaacata gataaagaca
    10021 ccaccgaaga cttgttctgt cacttgacct gttttcacat tttcaaatac gactgattct
    10081 actcggtttt cacccttgat ttcccttact acagaatccc agataaagct gattttttca
    10141 ttcgcaaagg cgcgatcttg taaaaccttt tgggcacgaa gttggtcacg acggtgaaca
    10201 atggtaacag tcttagcaaa acgagtcaag aagagggctt cttcaacagc tgaatctcca
    10261 ccaccaacta ccaataaatc ttggtcacgg aagaaagcac catcacacac agcacagtaa
    10321 gaaacaccac gactgttcag ttcttcttct ccaggtactc ccaaaggacg gtgtttagaa
    10381 ccagttgcta cgataactgt acgtgtttca tatgtttggt catcagtcat cactttctta
    10441 aaatcaccat ggtcttcgac attttcaaca taaccataaa tgtgctccac accaagattt
    10501 tcaagtggtt caaacatctt ttcagccaat tcaggtccac taatattagc gtatcctggg
    10561 taattttcga tatcagatgt attattcatc tgaccacctg gcagaccacc ttcaatcaaa
    10621 gctactttta gattgcttcg agcagcatac aaggccgcag tcatccctgc aggtccagca
    10681 ccgataataa tagtatcgta catatagatt ccttctttct tgttgtaact atctttattc
    10741 taactctttc ttgtcaatca cgcaaggatt atgccttgaa aacaagaatt aaactcataa
    10801 ccgcaaagga taatactggg acaaccaaga ctccaatcat aatcatatca tagagatggg
    10861 cttggcgagc cctggctgtc ttatcaactc ccgacatggc tctcagacca atccaaatcc
    10921 ctaaaaaaat cagaacaagg atggtggtca agatcaaact ctcgaaatat aaagaaaata
    10981 gttgcagtag catgatttct ctcatttcta tcttttttaa agagtaaact cagctagtcc
    11041 aactaactga gttttccttt atctattata tcaaatataa gtccgtttgt aactagcgaa
    11101 gaattctttt gtccgctctt ctttaggggt gtggataatc tcatccggtg ttccagactc
    11161 gatgattttc cccttatcta agaagagaat cttatcagcc acttgggcta caaaggacat
    11221 gtcatgacta accaaaatca tggtttgacc tgacttagca gcatctgcaa tagacttttc
    11281 tacttcacca accaattctg ggtcaagggc tgaagttggt tcgtctaaga gcaaaacatc
    11341 tggtttcata gcaagcgcac gcgctagggc aacccgttgc ttctgtccac ctgataaatg
    11401 gcgaggataa tggttttcac ggtccgaaag cccaacctta gccaactctt ccttggcaat
    11461 cttagtcgct tcttggtcag ataatttctt gacaacaacc aagccttctt tcacattatc
    11521 aagtgctgtt cggcgttcaa acaaattaaa ctgttggaaa accatagaca acttacgacg
    11581 tagggcaagg atttcttctt gagtgatttt agaaaaatca actgaaaaac catcaatctg
    11641 aatagagcca ctgtcaggtg tttcaagata attgagactg cgaagaaagg ttgattttcc
    11701 agctcctgaa gaaccaatca aggctacaac ttcccctttt tgaatatcca agtccagatg
    11761 atccaagaca gtctgtcctg aaaaggattt gcttaaattt gaaatcttaa tcattaacga
    11821 aggtctcctt tcacatctgt ttgcactgta tcaggtgcag aaatagccat ttttctctcg
    11881 atgaaacgac cgaggctttc aattccgata ttgaccaccc aataaacaag ggcaacggag
    11941 atgaagcgtt caaaatagcg ataatcagct ccacctagaa tctgagcttg ggcaaagact
    12001 tccacaacac ccgcactaaa agctagagat gttcccttgg tcaaaccgat gagggaatta
    12061 atcaaggttg gagtagctac caccgctgca ttaggaataa tcactcgtcg ataaacttgc
    12121 gctcgggtca tacccagact gcgtgccgcc tcaatctcac caggattaac tgagagaatg
    12181 gctgcacgaa tggtttcact agcataagct gcctcattaa aggcaaaggc gacaatcgca
    12241 aaagctgcag ctggaatcgc attgatattg agaccagttc cccattgctg attgagggct
    12301 ttcaaagcca aagggattcc gtagtaggtc aacatgagtt gcaccaaaat cggtgtccct
    12361 tttaagaaac taacaaagaa ggcctgcaag ggatataaaa tcttgacacg attgatcttc
    12421 acaatggcaa aaagaagcgc caaaaccaag ccaaaaaggg caccaccaat tgtcaacata
    12481 attgttgttg gaagttgttg gacaattcta gggattccat caaagaccga acgtaggcta
    12541 aacagcttgc catccggaat caattgcatc aagttttggt accaatctga tgctaaaatc
    12601 gttgtaacat tcataaaaac atcctcttct gataatgatt cattctacca tgcttctgcc
    12661 gtcaatgaaa ttatttgcta cggtcagata cagactttgt ctacctacta gtttatcata
    12721 ctttgaaaca gggaagttat atattttatc tatcaaagag atagataaaa actatttcag
    12781 tcccagttct tcataagatt ttcgataacc gatttgctta acagttccat tttctactaa
    12841 aataggccgt tttaacaaca taccgtcact tgctagcaac tcagccgctt cttggtttga
    12901 caaacttcct accttatctt ttagccctaa ttcacggtat ttgataccac tggtgttgaa
    12961 aaattgcttc aattcaaatc ctgaggtttc tagccaattc aaaatgactt cttggctagg
    13021 tgtttcttcc acgatatgga cggctttata gtccacacct aattgattta attcttgttt
    13081 tgctttttta caagttgaac atttggggta ttcgataaat tctaacatgt gcttctcctt
    13141 ctattgtttc tatctttaaa atctactcct tcatgctcca agagccaagc tttcttttcc
    13201 actcctgcag cataacctgt cagacgcttg cctgctccca acacacgatg acaaggtact
    13261 aggatagacc aaggattgcg tcccactgct ccaccaattg cttgagcaga agccacttgc
    13321 aggtcttgag caatttgtcc ataggtcact gtctgaccat aaggaatgcc ctgtaaatag
    13381 tcccaaactc tcttttcaaa attcgttccg attggcgcca agagcaagtt ggataaatcc
    13441 tgaggcttgc ctttaaagta atcatctaag caagcaataa ctgggtctaa aataggatga
    13501 ctaacaactt cttctatcgt ttcatctcct agtcccctct caaaatgctt ctgctcctga
    13561 acccaaattc catacaaata atggtcatca gctacaagtg atagaatacc aattggtgag
    13621 gagtagagga tttttacata cttcttttgc attatttctt taatttttga taggccaagc
    13681 gttcgccatc tactggcacc ttaccaactt gtttaaaacc aagtttttca aaaatatgtt
    13741 gcataacctt gttttcagca tgcgtatctg agcgaaaatc aagataatca aaaccttcaa
    13801 tcaagccctc taagaaggtt tgagcaactc cttttccctg cacatctgct gccacagcaa
    13861 tacggtgaaa gactagatac tctgactctc ccgcttgcca gtttccctca taaatagctt
    13921 cataggcctc ctctggactc ttggtcacag cagcataggc tagcagttct ccctcttcca
    13981 aggctacgta ggcttgccct gagatgatat catcgataat aacatctgca tttggatagc
    14041 cattttgcca ctggtcacta ccagcatctg ctaaacattt tttggcatcc tccatcacct
    14101 gcatgatggc atctacttca tttggaaaag ctaaacgaat ttccatcttt tttcctcatt
    14161 tctgactagt ttctcccatc atagcataat ttaagtattt ctacaagcag ttaaaacttg
    14221 actttgtgtt tttgttattt tataatctag ttatcaaaac tatataaaaa ggagttgaaa
    14281 atgaaaacta ccttttccta cccaaaatgg gcagaaattc caaacattga cctctatctg
    14341 gaccaggttt tgctctatgt caatcaggtc tgcgccccta tctctcctaa taaagacaag
    14401 ggcctaacag catctatggt caacaattat gtgaaaaatg gttacctgac aaagcctgac
    14461 aaaaaaaaat accaacgcca acagattgcc cgtttgattg ctatcacaac cctcaagtct
    14521 gtattttcta ttcaagaaat agcccagaca cttaatactc tacaaactca agcaagttca
    14581 gaccaactct acgatgcttt tgtggactac atgaaccaag gaattgaccc agctaaccct
    14641 attatccaaa ccagctgcca aaccgttaaa ctctatcatc aaactctaga cttaatcgat
    14701 catactcaag aggaggtaat ccaatgaaca ctagtcttaa actcagcaaa caactcagtt
    14761 ttggagagga gattgctaat agcgtgaccc atgctgtggg tgcagtcatc atgcttatct
    14821 tgctgcctat ttcatccatc tatagttatg aagcacacgg atttttatcc tctatcggcg
    14881 tttccatttt cgtcatcagt ctctttctca tgttcctatc atccaccatt tatcactcta
    14941 tggcctatgg ttcgacccac aaatatgttt tgcgaatcat tgaccattct atgatttacg
    15001 ttgccattgc cggctcatac acgcccgttg tcttgacctt gatgaataac tggtttggct
    15061 atctgattat tgtcatccaa tggggaacga ccatctttgg tattctctat aaaatctttg
    15121 ctaaaaaggt caatgagaaa tttagccttg ctctttatct gattatgggc tggttggttc
    15181 tggctatcat tcctgccatt atcagtcaaa cgacacccgt tttctggagt ctcatggtaa
    15241 ctggcggact ctgttataca gttggagctg gattttatgc caagaaaaaa ccttatttcc
    15301 acatgatttg gcatctcttt atcctagctg cgtccgcact tcaatacatc gctattgttt
    15361 attacatgta aaaaagttga gaaattcaat ctcaactttt ttctttacac atattgataa
    15421 agtactggtg caagcgcaca tcatcagtca attctggatg aaaagaactt accaacatat
    15481 ttttttcttg ggctgcaaca atttgattgt tcactgttgc tagaatttct acaccctcac
    15541 caacactact gataatcgga ccacggataa aggtcattgg aatcttgcca actcccttac
    15601 attctgcttc cgtgtagaaa cttcctaatt ggcgcccata agcattacgc tcgaccacca
    15661 tatccatagt tcctagatga ctctctttct gagaagtgat ttccttagcc agcaaaatta
    15721 agcccgcaca ggtcccaaac actggtaagc cagatagaat ggcttctcgg atgggaagta
    15781 gcatgttctg gtcacgtaag agcttgccca tggttgtaga ctcaccacca ggcaaaatca
    15841 aacccgacaa gtcactctga tcttgctgaa aatcatctag atttctgagt tctacactct
    15901 cgacacctaa ttgatctagc acttttgcat gttctgcaaa ggccccttgc aaggccaata
    15961 ttccgatttt catctatttt cctcgttcag ccatgagaat ttggatttca ttttcattaa
    16021 taccaaccat ggcttctcct aaatcttcag agatttgagc taggatttga ggattacgga
    16081 agttagtcac agccttaaca atggcactcg ctcgtttaac aggatctcct gacttgaaaa
    16141 tacctgaacc gacaaagacc ccctctgccc ctaattgcat cattaacgca gcatctgctg
    16201 gcgttgcaac acctccagca gcgaaattta caactggcaa ttttccatgt tcatgaacat
    16261 attggaccaa ttctacaggg acttgcaaat ccttggcagc aacataaagc tcgtcctcac
    16321 gtaagttttg aatgcggcga atttcctgat tcatcatacg catatgacga acagcttgga
    16381 cgatatcccc tgtccctggt tctcctttgg tacgaatcat ggaagcacct tcagcgatac
    16441 gacgcaaggc ttcacccaaa tccttagcac cacagacaaa aggaacttgg aattctttct
    16501 tgtccacatg gaaacggtca tcagctggag atagaacttc actctcgtcg atataatcaa
    16561 tttcaatagc ctctaaaatc tgagcttcaa caaaatgccc gattctgacc ttagccatta
    16621 ctggaatact aaccgcttct tggatttcct taatcatctt tgggtcgctc atgcgggaaa
    16681 ctcctccagc tgcacgaata tcagccggaa ttcgttccaa ggccatcaca gctgccgcac
    16741 cagcagcttc tgcgatacga gcctgttcag gattctgcac atccataata acaccaccct
    16801 tgagcatctg tgccaagttt ttatttagtt cataacgatt ttcagtcatt tgttttatcc
    16861 tcatcatttg tattggtagc taccttttca ttttaagtca gaacagaatg aagcacaaga
    16921 taaaaaaact ataattgtat ggggacagat tggctaaaaa ctatctgacc ttaacttaag
    16981 gccagatagc tcattcattt ttatctttca gccgtaaggg cagccattgt gatgtagttg
    17041 tatggtttat tgaagtgtgg caagaagaag aggtctgtca atgccaattt atcaattgtc
    17101 acatgctctt ggatagcaag tgagaacatg tggattccca tgctaattgc aatatcatgt
    17161 gaaaccattt gggcaccaag aatttcacgg ctatctttgt caaagacaat cttaattgct
    17221 acttcatggt tgtcatgttt catgaattct ggtttttgaa gatcgttaaa gcctgtttca
    17281 gttgcgttgt aaccagcagc tttcgctttt tcaagagtca aaccagttga aaccatgtga
    17341 agaccgtaga ttgagatacc atttgaacct tgaacaccga ttccttccaa ttcatgtcca
    17401 caagcgttgt aggcaccaac gataccagtg cgaacagcat ttgaagcaag agcgatatag
    17461 cttgtatctt tacgagcatt gtcataaaca gtcgcacagt caccaacagc gtaaacgcct
    17521 gggatagatg tttcttgttt cttgtctaca aggaaggcac cgttgcggaa gagttcgatc
    17581 ttaccatctg caagggctgt gtttggacgg aaaccaactg caaggataac catatccacg
    17641 tcaaagcttt ctttgtcagt aatcaagcgt tcaactttac cgtcaccttc gattgcttta
    17701 acagtttgac ctagagccaa gcggatgttg tgatcttcca agttcttcgc catcatttgt
    17761 gtgaagtctt tgtcatagta accgttcaag acagtatcaa cgatatcaac aaggacaact
    17821 tcttttccaa gacgttcaaa ggcttcagca agttcaacac cgatgtaacc accaccaaca
    17881 acggcgatac ggtcgaggtg ttggctcttg tcagaaagtt tattgataac ttcttcagca
    17941 ttttggtaca atttcacgaa ttgtacgttt tcaagagttg ctttaaattc gcggtttcct
    18001 ttaacaattt caacaccttc gattggtggc aagattggtg tagaacctgt agcgaaaatc
    18061 aatttttcgt atgattcttt gtgctctttt ccttcaactt ccgctgtaac tactttgtta
    18121 tcatagtcga ttgaaagaac aggtgagttc atgtaaactt tagcaccttt agcttccaat
    18181 ttttctttat cagaatagaa caagccttca gcaccgtcaa tttgttcacc aatccaaaga
    18241 gccattccac atcctaggaa agagatgtta gagttttggt caaatacaac aatttcgttc
    18301 tcatttccaa aattatccaa catggtattg atacatgctg taccagcgtg gttagcaccg
    18361 actacaacga ttttactcat aaaaatttcc tgccttcatt ctaaatttac cttactagta
    18421 taccatttac cgttagcgtt tacaaggggg gtactattat ttcagcattt tttatcaaaa
    18481 ataattcccc atttatcctg ttttcaagcc tcatgaattt tatgagcata tttcttgact
    18541 ttttccaaat tttgtttgtg aaaattctaa ctttatggta ttataataac atgaaaatga
    18601 aatgtaaggg cttcaattta gatgattatt tgatattaca acttattttc tataagagaa
    18661 aggagttggt agcttgactc ttcgttcaca ttctgaacgg ctaatgggga ctactatcac
    18721 tatttcatta gtggatgagc aagccgatat ctttctccaa aaatcctttg acttgctcaa
    18781 agaacttgaa taccgcttca acgccaatag tcaagaatct gagttgatgg aaatcaatta
    18841 tcaagcagga atagcccccg tcacggttca tccagacctg tttgagctga tttcacttgg
    18901 gttagagcat agcctagcgc tctctagcca cctcaatatc agcattggtc ccttaattca
    18961 aacctggcgt atcggttttt cagatgccaa ggtcgcccag cctcaagaaa ttgaatcggt
    19021 gctgcctcta atcaatcctc atggtatcga gttagattct tctacttcta ctgtgttttt
    19081 aaaacagaaa ggaatgaaga tcgatctagg ttgtttagcc aaaggataca gtgcggataa
    19141 ggttgcccaa tttcttagga aagagggggt gacttctgcc ttgatcaatc tgggagggaa
    19201 tatcctgacc attggaaaaa atcaggcaag aggggataac ccatggcaaa tcgggattca
    19261 agacccagcc aatcctaggg gaaatcattt aatgaccatc cctgttgtca ataaatctgt
    19321 cgtgacttca ggcatttatg aacgtcacct gaccgtcgat ggacaagatt accatcacat
    19381 ttttgacagt caaacaggat atcctgttga aacggaacta gcgagtctaa caatcatctc
    19441 tgataaatca gtcgatggcg aaatctggac gactcgactc tttggagaaa gacctgcttc
    19501 tatcctctgg caagtcgaaa gtttggaggg catcgaagtc atcctcatcg ataaagaagg
    19561 ccacctaagc tgttcttcag gaattcctac tctatagaga caactgtttc aatggaattt
    19621 taaaattgta ttatgtaaaa agagaaagga aatctcatgt taaaacttat tgctattgtt
    19681 ggaacaaatt caaaacgttc tacaaaccgt caattgcttc aatacatgca aaaacacttt
    19741 gctgacaaag ctgaaattga gcttgttgaa atcaaggcca ttcctgtctt caacaaacca
    19801 gctgacaagc aagtacctgc tgaaatattg gaaattgctg ctaaaatcga agagacagat
    19861 ggcgttatta tcggtactcc tgagtatgat cactctattc cagctgtttt gatgagcgct
    19921 cttgcttggt tgtcttatgg tatttaccca cttttgaaca aaccaatcat gattacaggt
    19981 gcttcttacg gtacgcttgg ttcatctcgt gcccaattgc aacttcgtca aatcttgaat
    20041 gctcctgaaa tcaaggcaaa tgttcttcca gatgaattct tgctctcaca ctctcttcaa
    20101 gcatttaacc caagtggcga cttggttgac cttgatgtta tcaagaaatt ggatgccatc
    20161 tttgatgact tccgtatctt tgtaaaaatc acagaaaaat tacgtaatgc acaagaatta
    20221 cttcgcaaag atgctgaaga ctttgactgg gaaaatttgt aagataggag accaaaaaga
    20281 atgaaatttg ttggacttgt tggatcaaac tacgatcaat catataaccg taagctcttg
    20341 gaatttatcc gtcgctactt caaactcaaa tttgaattag aagttcttga aattgacgaa
    20401 gttccaatgt ttaaccaaga tgaaaaatgg gatgaaagtt tccaattacg ttatttatat
    20461 aacaaaatta ctcgtgcaga tggtgttatc attgctactc ctgagcataa ccacactatc
    20521 tcagtttcac tcaaatctgt acttgaatgg ctttcatacg aagttcatcc atttgaaaac
    20581 aagcctgtta tgattgtggg tgcatcatac tatgaccaag gaacatcacg tgctcaagtt
    20641 caccttcgta aaatccttga tgctccaggt gttaatgcct acacgcttcc aggtaacgaa
    20701 ttccttcttg gtaaagctaa ggaagctttt gataacaacg gaaatatcac caacgaaggc
    20761 actgttaaat tccttgaaac ttgcttagat aactttgtta aatacgtagg agtcgtttcg
    20821 aaattgaaaa aaccaaaacc aatcgaatca gaagacttgg attgtggaaa accaatcgct
    20881 acaaccatca cagaagttga ccctgacgat ccagaatggg tagaaaaagt tgcagcaatc
    20941 actggtgctg tttctggtga tacctatgtc aaattggacc acggtatcct aacagttaac
    21001 caaattgata tgttcttgaa agctatgcca tttgaattga catacgctga cgacaacaac
    21061 caattcctct actacaacaa cgctcaccaa gatccagaca ctatgttcgc taaacgtgta
    21121 ccacctcaat caggtagccg tatgtcgact gttcatggtt ctcttccacc agcacgtatg
    21181 aagaacgtag agtgggttat cggaacactt cgcaacggaa accaagaata cgtccgtacg
    21241 atcgttccag gttctcctgc aggtgttatc aacactcaca actaccaagc aatgtactat
    21301 cctgatggat catacgctgg tatcaatgaa atcgtcttta acttccaacc atggcttgac
    21361 tggtacctaa aagagactgg tcaacgtttg gtgggtggta gcggaccatt tgctcctgct
    21421 gccggaggtc atggaaacgc cgatgctact tctggcgctt ctgattcagg ggatgctgga
    21481 ggccacggtg gtgacgcaga tgctacagcc ggtgcaagtt actaatgata gtttttagga
    21541 accattatgg ttcctttttt agcgaaaaaa gactagcaaa cacaaactgc tagtctcttt
    21601 gttatcgttt catctatctt tgttaaaaga aaaatacata ttatgaattt gggtcatcaa
    21661 gactacggcc atgtaatcct ttttcacgtt gtacttggcg tagtttttct ggtgtaacat
    21721 cgtttccttt ttcgtccaca attttgattc cttcaatgtg atgacgaaca gcgcgacgat
    21781 aaccttcgat gtactcctca cgtagtttgg cttgttccac tttttcttct ggtgttaagc
    21841 cttctgtttt tttcttttta gcaagctcat tgatacgagc aatttttttc ggatccattt
    21901 cttctcctct gtaataagat aaagtccgtt tatcaaattt tatttagtgt taatttggtt
    21961 aaaacaagca aacttagctg ctttcttggt tagttgtgac aagattgcca aacgattttg
    22021 acggacagcc tgatcttcag ccattaccat agtattttca aagaaagcat caatgactgg
    22081 gctaagcgca aaaagttgtt tcaattgctg acttgcaggt cctgataaaa tgagtgtttc
    22141 tactgcttct gccaaagctt tttcttggtc attctcaaat agtgctgaat caaccgtagc
    22201 aaccccttct gccttctcag ccaggttaaa ggcacgagaa agtgattcaa cagatggttt
    22261 aaaatcttct tccttgctta cttctacgag agcacttgct gcttccaaca tatctgccac
    22321 aacaaagttt gaacctgcaa gaactgcttc cttgatatct tttggagtag agcccatcat
    22381 cttatcaaca cgagccttga taaagtccat aacctctgct ttattttcat aagtcaaact
    22441 gtcaaatttc aatgcataaa ggctatcaat cagctcatcc atagcaatgt gccaaccaaa
    22501 ggcatccaag atacgaacca caccttgagt tgcacgacga agggcataag ggtcattaga
    22561 acctgatgga atcaatccta ctgagaagaa actcaaaatc gtatccaatt tgtctgcaat
    22621 ggctagaact gcaccgacct tgctctctgg aagttctcct tcagctgatg taggcatgta
    22681 gtgttcacga atagcagctg ccaccgctgg agtttcacca gcaagaaggg tgtatttttc
    22741 acccataatt ccttggagtt cgtcaaattc accaaccata cctgtcaaca agtcaaactt
    22801 gtaaatggct gctgcacgag caaggtcaac tgtttcatcc actgacaaac cagctttttc
    22861 tgccaaaagt acagtgattt gacccgtacg aatcatgtgt tcacgaaggg aaccaatctt
    22921 ctcatggaag gtaacattgt ttaatttttc aacaagatct gaaatcacca atttttggtc
    22981 ttcacgccag aagaattctc cgtcttccaa gcgggctacc aagacttttt catttccttt
    23041 aatgacattt ttcaaacgct ctgcgtttcc gttacgaaca gaaatgaagt ttggcaagag
    23101 ttttccatct tgatcacgaa caacaaagta acgctggtgt tccttcatag aagtcaccaa
    23161 gacttcttct ggaacttcaa ggtatttagc atcaaaactt cccatgaagg cagttgggta
    23221 ttcaaccaaa ttcaagactt cattcagcaa atccgcatca atttcgatac gtacaccatg
    23281 ttttgcctca atttccttga tttggtcaac aatcatttgc tcacgttcac atggatctgc
    23341 gattacaaac tgcttacgaa ggtcttcttc atagctcaat gctgactgaa ttttggtttc
    23401 tttccccaag aaacgatggc cacggctcac acgacttccc ttgatatcaa ggaaatccaa
    23461 gtcaaactct tgctcatcca agagaacagt taaagtgtga acagggcgga tgtattcaaa
    23521 gctatttcca gcccagtgca tgctgacagg gaaagtcaat gacttcaaga catctacaac
    23581 accaggaaca atggcttcaa ctgattggcc aacttcttcc ttagtgacat agacatattc
    23641 ttcaccctta atttcacgga attcgatatc ttcaacagtc aaacctttcc cacggacaaa
    23701 tccttgagct gctttggtga agtttccatc actatccaag gcaattttct ttgctggtcc
    23761 cttgaaatct tctgtcaaat cagactgttt gtctgataaa ccagtcacac gaacagccaa
    23821 acgacgtggt gttgagaagg tttgaatggc ttcaaaagac aggcggtttt ccttgaggaa
    23881 ggctgccatt ttttcgccta gttgtttttc acttggtgtg acaacatagg ctggtaattc
    23941 ttcaagaccg agttctacta ataagttttt tgtcatgttt tttgtcatgt tttttctccg
    24001 aaaagtatct ttttattttc cagtttgcct tatgtgattg gcacgcaagc aaccaacttc
    24061 gttgtttcat tgctaaaatt ggagccaaaa gtctccaatt ttgcctagta tccttagttt
    24121 cactaaggat accttcatca ctgcggcaac tggctcaggg ctcactctgt tcgcccattt
    24181 tcgtaatttg tcactctctt tattctgcgt cttctgctag gagtttagct cttgtttctt
    24241 catccaaaag tgggtagcct aggcgtttgc gttctgcgac aaaggttttg gctacgacac
    24301 gggccaagtt acggatacga gcgatatagc ctgcacgctc tgttacagat acggcaccac
    24361 gcgcgtcaag cagattaaag gtatgtgaac atttgagaac atagtcatag gcagggtgta
    24421 ccaagccttc ttctaatgca cgaccagctt ctttttcaaa cttatcaaaa ttttcaagca
    24481 acatttcttg gtccgaaatt tcaaatgaat attttgagtg ctcatactca ggctggataa
    24541 agatttctcc gtattttaca ccatcagccc actcgatatc atagacagag tctacttctt
    24601 gaatgtaaga agccaagcgc tccaaaccat aggtaacttc cgcagtcaca gggctagttg
    24661 ccaatccacc gacttgttgg aaataagtga actgagtgat ttccattccg tcaagccaaa
    24721 cttcccaacc aagaccagct gaaccagttg atgggttttc ccagttgtcc tcaacaaaac
    24781 gaatatcgtg ctccaaagga ttgattccca atttttccaa agactcaagg taaagttctt
    24841 ggatatttga tggagaaggc ttcatgacca cctggaattg gtggtgttgg tagagacggt
    24901 tagggttttc cccataacga ccgtcagcag gacgacgtga tggctctaca taagctgcat
    24961 tccatggctc aggtccgata gcacgaagga aagtgtaagg actcattgtt cccgcacctt
    25021 tttcattgtc ataagcctgc ataagcatac aaccttggtc attccaaaat cgttgcaaag
    25081 tcaaaataat ttcttgaaat gttaatttct tagacattga atactcctta ataaaaaata
    25141 atttcttgcg acacgagtct acctcgtcga ttatacgagg caagacgagt tagtactgcg
    25201 tctagctcag caccctagtg ctgagcgtgg ggcagtccga ctgtaaggag gtctctgcca
    25261 ctgatgcagt gaaatgtcaa tttcttagac attgtttact cctttagttt ttatatttct
    25321 ttttcaatta atttctgctg aacaaaccaa tctaacaagg gaaaagtttt ttctgtattt
    25381 gcccataaat gataagaatc taagaccgct tgtacactac ctaaattttc taccaactta
    25441 tctactgtca aaaagctgcg ccagtattca taaaaaatac ttgcatagtt cttatcataa
    25501 gtcgaagaac caaaatcatt caatgaatgc caaccatact tcttctgaaa aagttctacg
    25561 agagattgat tacaaatttt ttccgcttga aattcctctt ctgtcaagaa atacttgcga
    25621 ctaatatatt caaccatccc ctcttcgaac cagatataag agtcataacc atcaaaatca
    25681 tctaaaaaat gctccgacca atgagctaac tcatgtccta caatctgtaa gaggaaattt
    25741 tcagataaag aatgatagtg actttctatt gcttgagttt gctgagaaca ctcgtagtcc
    25801 atcaattgat acaaatacaa ctctttccaa acagctaaat caggcgccat aaccattcgt
    25861 ctattatttg tataggctgg aacagcgctt tccctaataa tctgtgtagc agcattaaaa
    25921 tctgaccaaa taacggcttg cggtaaatca cagactgcaa gttcattctt taaaaaagat
    25981 tgataatctt tcaacttttc agtatttctt actacaaaat cacgaaatgt agctagttga
    26041 ctatcgtctt ttacaagata aaggttgtcc acggctctcc tttctttcac acaatagact
    26101 gaataagcaa aagaaccaca tctgacaatc ctaggttgat ttaacctagg ggcgtcagaa
    26161 acgcggttcc accctaattt attacttcat tgtttttgaa aatactacag aaagcgccag
    26221 ccctttattt tgccctactt ggctcccact atcccaagct cgcttgaaga acgccataag
    26281 actttctttc ctgctgacta ttatatcaaa aattagaata atgtacaatt ctttttatga
    26341 ttttctagaa atccacatca tcaactcgtg gagcacccga ttgaacagca atcgttttta
    26401 aggtttctct ctcctcatga ctcagttcaa ttccaaagca atcaagatta gcttgaatac
    26461 gagaggttgt gatagatttt ggaagtggta aaaatccttc tgccaagctc caggccaagg
    26521 ctatctgagc aatcgatttt ccgtgatttg ctgcgatttc ttgcacttgc ttgctatcaa
    26581 atagttctcc ctgaccaaaa ggcccccaag cttccaataa aattcccttt tcacgacagt
    26641 aagctacgac ttgatcttga tacacacctg gcgccaagcg aacttgattg accgcaggaa
    26701 cgatagttgc agtttcaagc aaggcatcca aatgatgggg aagaaaattg ctaacgccga
    26761 tagcacggat tttcccttct tgatagaggt cttccatcgc tctccaaact tccgcattgc
    26821 gagttttcca tgcgtcattt tctctgagcg gttttgggtt cggccaatga atcaaataca
    26881 aatccaaata atccaagccc agtttttcta tagatttttc caaagcttga cgagtttgct
    26941 cataggtttg ctgactattc caaagcttgg tagttacgaa catttcttca cgtggaactc
    27001 cgctatcttt gattgcttga ccaacacttt cttcattctg ataaatcgcc gccgtatcaa
    27061 tatgacgata accagccttc aaggcttcta acactgcacg ataggcttct tctccatcct
    27121 tagccttaaa agttccaaat cccaatactg gaatttctac tccattattt aattgatagg
    27181 tattcatatg cttctccttc tattttattc atcaattata gcataaaaca ttttttaagt
    27241 agtactatct tctgtaaaaa ataagtctgt caaatatcta acagacctat tttttcttgc
    27301 ttattcatca cgactatagt acagctcatg agcttttagg cgagtattga gcatctctgg
    27361 tatggtcaca aaggtataac cttgattttt caaatactca atgacccttg gcaaggcatt
    27421 gactgtcgga ctgtgaatat catgcatcaa aacgatagag ccgttagcta cttgatgctg
    27481 aatttctgtc aaaatagatg cttcattttt actcttccag tccagactat ccacatccca
    27541 catgataaag ctcaaatcca agctattgcg aatatcatct gtaatagcac cataaggtgg
    27601 acgcatgagt ttagaactag aacccagcac tttagttagc acatcctcag tatcagtaat
    27661 ctgcttttta gcttcatcaa gagagagttg cgagagaatc ggatggctcc aactatggtt
    27721 tccaacaaca tgaccttcag attttatcct cttcaccaag tcctcattcc cagaaacatt
    27781 tttcccaagc acaaagaaag tcgctttaat atcatattta gctagggtct ctaatacctg
    27841 cggggtcgtt gctggatttg gaccatcatc aaaggttaga gcgacaactt tttgatattt
    27901 cttatcaaag taagattggt acaaggccgc atctttttcg agtaagtacg aagattggat
    27961 aacatcaaag aaagcagata ctggcaaggc tatctcttct aaattttcaa ccacaggact
    28021 tggataaagg ataatctgac tatccttgta atcaaaattc catgcagaca agtcttggtc
    28081 agagaagttt tttacaatct gctcactctg gtcttgctct atttttttat cctctatgaa
    28141 ggaggtcaac tcttttatca gctgttcctt agccttacta gcatctgaaa acagttggtc
    28201 aagtgtaaaa ggttgcccat cttctgttaa gtgaaccttt cctagactgg tcttttcagt
    28261 ctcttcaatc ttaaaagcaa ctaaatcata gatttgtttg gtcacattac gattaacgac
    28321 tccctttaaa cctgactctt cttgctctgt atagtagaaa acaagattgt ccttactttc
    28381 tagcttgtcc ttaacatctt gatttatcag ctccctaaca gaggaaatca ctttctcccc
    28441 ttggagagga taataggcaa tcacttcggc ttgcccctga cgaaaatgct ccttctgatt
    28501 tccctcactc aattgatcat ctttctcttt tttgagcgat tcaatctttt gctcaaaact
    28561 tttttgctgg tagatcttaa aagcaataaa tccgcctaat aggcaaatag aaattgctaa
    28621 gataccaatc aaagccaata atacatgtct cgttttcccg tgtctgccac gtcctagtct
    28681 acttttattc atatttatat cataacaaat ttgagcaata atttcaatga tacaatttgg
    28741 caatccacaa ttcctctagc aagccaaagc atcttacatc aactccaaca tccgtatctg
    28801 tagagattat gtagttttct atctatggaa tttctagtag attgaagcta gaatagtaga
    28861 cctatacttc taaaacattg ttagaaatcg atttgactgt cctgatcgat ttgtcctgtt
    28921 ctcatttcat tttactataa aactatgaaa agctaggtca tctgagaagt aattactatc
    28981 gacaattgcg atagcgtata ctggtgcgat gtgtttgtag ctctggtggg tatcaccttc
    29041 acgttggcaa attttttcta ggttttgatt aacctgactg cacagataag cccataggcg
    29101 attgatgaaa aaattctgat gatgaacctg aatttcgatg ataacttgga ttccattatc
    29161 taactccgcc aagacgtcta tactagtata gaaatcctgc gctgagtagg gcatggaagg
    29221 caagacgtga atgttacttc cctccaaaat cgtcacattt tttgctggca agtccagcat
    29281 atcgcggata aattgacaaa tcattagttg ggctgatacc cggatgtctg agaatcctcc
    29341 ttttcctcct tctattatag cacattttta aatctaggtt tgctagattc tatgcttcta
    29401 tctatttatt cggaaaagaa agtttttctt cagaagaaag ctaatagctt atttgaaatt
    29461 ttctcctctc tgttggatag tcccgtctat ctatgttata atgaaagaag gatttaaaat
    29521 cggaaaagga gtatttatgc taaaattagg tgtcatcgga actggcgcta tcagccatca
    29581 tttcatagaa gcatcccata ccagtggaga ataccaactg gtcgcaatct attctagaaa
    29641 actagaaact gcagcaacct ttgcttctcg ctatcaaaat atccaactat tcgatcaatt
    29701 agaagtcttc ttcaaatctt cttttgattt agtctatatc gccagtccaa actccttaca
    29761 ttttgctcag gcaaaagctg ccttgtctgc tggtaaacat gttattcttg aaaagccagc
    29821 tgtcactcaa ccacaagaat ggtttgattt gattcaaaca gctgaaaaaa ataactgttt
    29881 tatctttgaa gcagctcgta attatcacga gaaagccttt actactatca aaaacttttt
    29941 agcagataag caagtgttag gagcagattt caactatgcc aaatactctt ccaagatgcc
    30001 tgacttgttg gctggacaaa caccaaatgt cttttcagac cgttttgctg gtggagccct
    30061 catggatttg gggatttatc ccctctatgc tgctgttcgt ctttttggaa aagccaatga
    30121 cgcgacttac catgctcaac agcttgacaa tagcattgac ctaaatggag atggtatcct
    30181 cttctaccca gactatcaag ttcacatcaa ggctggaaaa aacatcactt ccaatcttcc
    30241 ttgcgagatt tatacaacag atggaacctt gactctcaac acgattgagc atattcgctc
    30301 agctattttt accgaccacc aaggaaatca agtccagctt cctatccaac aggctcctca
    30361 tacgatgact gaggaagtcg ctgcatttgc acacatgatc cagcaaccag atctgaatct
    30421 ctaccaaact tggctgtatg atgcaggctc tgttcatgag ctactatata ccatgcgcca
    30481 gactgctggc attagatttg aggcagaaaa atgaaaacca aactaccgac tgaatggcaa
    30541 gaactgagtg accaactcgg tttccaagaa ttcaccccca ttcaaactca actatttgag
    30601 ccccttcttg ctggagaaaa cctcctagga gtgagcaaaa ccggaactgg taagacccta
    30661 gcgtatctcc taccaagtct tctcagacta caaaagaaaa aagcccaaca actcttgatt
    30721 ctagcaccaa atacagaact tgctggacag atttttgatg tatgtaaaac gtgggcagaa
    30781 gctatcggat tgactgctca actcttcctt tcaggttcaa gtcagaaacg acaaattgaa
    30841 cgtcttaaaa aggggccaga aattctgatt ggaactcctg gccgtatctt tgaactcatt
    30901 aaacttaaaa aaatcaagat gatgaatgtg gaaaccatca tcctggatga atttgaccaa
    30961 ttactagatg attctcagat tcactttgta gaaaaaatca ctcactacgc acctcgtgac
    31021 caccaactga tctacatgag tgccacgacc aagtttgacc aagaaaagat tgtgccgaat
    31081 acacgcacta ttgatctctc tgatcaaaaa ttggacaata tccagcattt ctacatgcag
    31141 gtagaccaac gtcatcgagt ggatatgcta cgaaaactgg ctcatgtaga ggatttccgt
    31201 ggtctagtct tcttcaatag cctgtcagac cttgggaatg ccgaggaaaa actacagtat
    31261 cgtgatatat tggctgtttc cctcgctagt gatgttaatg ttaaatttag aaaagtcatc
    31321 ttagaaaagt ttaaagataa ccaactaacc ctgcttcttg caactgacct tttggctcgt
    31381 ggaattgata tcgatagcct agaatgtgtc gtaaactttg atattcctag agatagcgaa
    31441 acctacacac accgtgctgg ccgtactggc cgtatgggca aggaaggata tgttattact
    31501 ctcgtcactc atccagaaga aatcaaaaaa cttaaaaagt ttgcaagtat ccgagaaatt
    31561 gtcctaaaaa accaagaact ctatatcaaa taaagcccca ttgctctata cacatccagt
    31621 gtatggagct tttttataag caattcaatt ttatactcat ctgctttcaa aaagcattct
    31681 agtccatctc cgattaacga tggactttat cacctccttc tccagtcctt gtatgacatc
    31741 ttggagttga ttcatgacat cttccaaagt tcgaaaggct ttattcttaa atccacgttt
    31801 acgaatctct ttccacactt gttcaatggg gttcatctct ggtgtgtacg gaggaataaa
    31861 tgcaaagcca atattagtcg gaatctttaa ggtacttgat ttatgccata tagcattgtc
    31921 tataacgagt aaaaaataat catatggata agcttgtgaa agctcttcta aaaagacgtt
    31981 catccactca gtattacatc caccagctat taagaaaact gatgcgcctg tatgggcatc
    32041 aacagctcca taacaatagc gaaattctcg tatatagtga ctatggatat gtggacctac
    32101 tcctattgga gcccaacaag atcccagttt actgattcta ccgaaaccag cctcatcttg
    32161 gtacatcaag cgaaccttac gaaaacgtct actggtttta aagcgctttc ttgtcttctt
    32221 gaattgagat tttattttta gatgcgacaa tggtttgagc gtctgctttc ttaggatgtt
    32281 ctggacgtgg cgtaatattt cgccaaccat ggcgcttcaa cagttgatag aaggcatcac
    32341 gtgtgtagga acgacctaac tcctttttat aagcctgaaa taaggcatca attgtaacaa
    32401 attctcctgc ctctgcagcc ttcaaatggc gggcaagaaa ggctttttct tcctcaactg
    32461 tcatatatga tggttacgac caccacgtgt ttcttgaagg agagagtcga gtccgaactc
    32521 ctcatatttt tttacatttc gccaaatcgt tgtttgatta cagtctaaaa gctctataat
    32581 ctctttataa gatttgccca tcagacgaaa tagaacgatt tgaaggcgtt tatgatattt
    32641 agctgtacga gagtctttta aaagtgtttt gatggtttgg atttcttctt taattgattt
    32701 catattacta ttgtataatg ctttttgatt ttagtctagt attatactct tcgaaaatct
    32761 cttcaaaccg cgtcagcttc gccttgtcgt atagatgtta ctgacttcgt cagttctatc
    32821 tacaacctaa aaacagtgtt ttgagcagtc tgtaactaac tttctatagt aaaatgaaat
    32881 aagaacaaga caaatcgatc aggacagtca aattgatttc taacaatgtt ttagaagtag
    32941 atgtgtacta ttctagtttc aatctattat agtttactct ttgattttca ttgagtatta
    33001 gttcaatatc taaaaaaaga accttgccaa gcaagattct tttagtgtct gacttaaata
    33061 attgttcttc tgggaactaa atcgaattaa gcttcgattt ctgtaaccat acctgaacca
    33121 acagtacgtc caccctcacg gatagagaat gtagtacctt gttctacggc gattgggtga
    33181 atcaactcaa cgtcgattgt cacgttatca ccaggcatta ccatttcagt acctgctgga
    33241 agttcgattg aacctgtaac gtcagtagta cggaagtaga attgtggacg gtagttgttg
    33301 aagaatggag tgtgacgtcc accttcttct ttagtaagga tgtagacttc acctttgaat
    33361 ttagtgtgtg ggttgattga acctggttta gcgataactt gtccacgttc gatttcatca
    33421 cgttgaacac cacgaagaag gacacctacg ttatctccag caagaccttc gtcaagttgt
    33481 ttacggaaca tttcaacacc agtaacaact gctttttgag tttcttcttt gataccaacg
    33541 atttcgattt cgtcgttgac tttaacgata ccacggtcga tacgtcctga agcaactgta
    33601 ccacgtccag tgattgagaa tacgtcctcg actggaagaa gcaatggttt gtcagtgtca
    33661 cgttctggtt ctgggatata ctcatcaact gtgttcatca attccataac gatgtcttcg
    33721 tatttagagt caccttcaag agctttaagt gctgaacctt ggataactgg aagatcgtca
    33781 cctgggaagt cgtattctga caataggtca cggatttcca tttcaaccaa ttcaagcaat
    33841 tcttcgtcgt caaccaagtc aactttgttc atgaagacga taaggtgttt aacaccaacc
    33901 tgacgtgaaa gaaggatgtg ctcacgagtt tgtggcattg gtccgtcagt tgaagctact
    33961 acaaggatag ctccgtccat ttgagcagca ccagtgatca tgtttttaac gtagtccgcg
    34021 tgtcctggag cgtcgatgtg agcgtagtga cgtttttcag tttcgtactc aacgtgcgca
    34081 gtgttgatag tgataccgcg ttcgcgttct tctggagcag catcgataga cgcatagtct
    34141 ttaggttggt taactgatga aggcaagcga cgtgccaaaa cagttgtgat agctgcagtt
    34201 agggtagttt taccgtggtc aacgtgtccg atagtaccaa tgttaacgtg tggtttacta
    34261 cgatcgtatt tttcttttgc catttgagta aaagcctcca ataaaatata ttttatagat
    34321 agacagtagg caatacagtc taactttcct tactatttta tcaaatttca gctaaattgc
    34381 aagtgtttta caacgttttt gtgaattatt cttggtaaaa atttaactaa ttaatagaaa
    34441 gtactaaata gacttatcct tcaaggagtt ttcagcatta tccatccact cacttgctga
    34501 aaatgtaaac agtctctggt ttatatagta aaatgaaaca agaatagggc aaatcgatca
    34561 ggacagtcaa atcgatttct aacaatgttt tagaagtaga tgtgtactat tctagtttca
    34621 atctactata caacctcaaa actgtgtttt gaacaacctg cggctagctt cttagtttgc
    34681 cctttgattt tcattgagta taaaattgca gataaaacga taacaatcat aggactcagc
    34741 agagtcaatg taggtcgaag aatagccccc ctaatcgctt attttatagc aaaatgaaat
    34801 agaaactgaa cattttgttg aggaaggtaa atcaattcct cacaatgttt gagaaagaag
    34861 gggggactat tccaacttca atccactata aagcagactt acaagatagg gaacccatct
    34921 ccgataatat atagtagaat gaaaactgca caatttgatt ggagaattca aaccaatttc
    34981 taacaatgtt ttagaaacaa gggtctatta tttcaactgc aacctactat agcccattga
    35041 agctggaata gcccactgaa acttctaaac cactgctgga gaggagtttg tttagagttt
    35101 ctttcatttc cctaaaaaat caaaaagaga gaaccagtct gatcctctct tacttataga
    35161 tggtgctcac tcaaatgtta aaggagctat ttcttagaga taaaggaatt tgaatacagc
    35221 tactgccgca attgctgctg cgataggtgc tactactggt acccaagaat accaccattt
    35281 tgaatcgcct ttatgctcac caagaactga ttttggaagg aaagcatgaa ggagacgtgg
    35341 tcccaagtca cgggctgggt tcaaggcagg tcctgtaggt cctccaagtg atgttaccaa
    35401 agccataacg aggaatccaa gtgccaagtg agccacagaa agtcctgaag cagtgtgtgg
    35461 agccacctgt gctttaatag ccaagtcaga aaaatcaact gtttgtcctg cttctattgc
    35521 cttttgtttc atgaattgaa gcacttcagc accaaagaag tttttagtca aaccaagagc
    35581 tgcaaagaac aaaacaaatg aaccaacaaa ctcattaatc aaaccattga cagttgctgc
    35641 atagcgactt tcttttgtac catggtcaat acttgaaata gttgagaaag ttcccaagat
    35701 gttatttggt ttttcagttt tcaagtagaa tggacggtat gttgccacaa ctaaggcttg
    35761 gccaaagata gcccccaaga cttgcgcgat aatgtaaggt accacttgtg cccaagggaa
    35821 aagaccgcta actgcaagcc ctagagtgaa agcagggttg atgtgattcc cagatacgtt
    35881 accaaacatc aaggctggga tcataacccc cataccataa ccaacagcga tgacgatcca
    35941 gccactttgg tgacctttcg tacctttaag ttcaacgttg gcaactgcac cattcccaag
    36001 aatgatcaaa atggcagttc ccaaaaattc agtggcatac ttcagtgccc atgtgaaatc
    36061 catttgctag attctcctta aaatttttta gatattcctt attttatcaa tttttaccct
    36121 atttagcaac tgatttctgg aaatattttt aaaaaaatag gattcatagt ttcccagttc
    36181 aacgtacttg taagcgtttt tattcttcac gaaagacctc gttctcaaaa ccaggaaaaa
    36241 agcccacatc tgtgagcttt tcctggttcc tagattctaa aatctattat ttttcatctt
    36301 cttttttctt gaagaatcct aatactagac tagctaacaa ggtcatgata ccagcactag
    36361 ccaaggtagc attagcttct gtacctgtgt ttggcaattc ctctctctta cctgtctcat
    36421 aagtcggaac ttctgggtct ggattcactg gagtttcagt ttttggagta cctggttctg
    36481 gagttggctc tggtattgga gtctcttgat ttggtagttc tgggtttggt gtcggaacac
    36541 ttggatgctc tggatttggt tgtgggattg gtttttctgg agtcggttca cctggagtac
    36601 ctggttcctg aggacttgga atttctggtt tttctggagt tggtttatct ggtgttgata
    36661 aacggtcata ccttaccgtt atttctttat cactagagtc tgacgtaact tcttgtgatt
    36721 caactgttgg aatatctgga tctttgtact tgtcaatctt accagatata acctcgtccc
    36781 agtttcctgt tgtccattca ccgtaggtta caactcccgt gaccttgttc tcagtttttg
    36841 tacggcttaa ggttacaggt tgaacaacat cttcttttac attttggttc gtaactttat
    36901 caacgtaatg aatgatacgc gttatagtct tcgtctcagt agaggttgct gttttgggaa
    36961 ccactgtttc ctcaacattc tcacggtagt aatagtcaac tgttgcaccg tcttctggta
    37021 cgcatttgca ggagttgcta ccaaggtgta tgttgttttc cttgtgataa ctcggtcttc
    37081 tttgtcctca gttgttgttt tcccttcaat agtttttgat tctgtggtat actcagaacc
    37141 tatcgctaaa tcagctttta taacagactc tgccaacttc tcttggctac cttctttata
    37201 gtaattggct gttactgtag cagtggttgg cgcttcgctt tctctataaa ctaaggtcac
    37261 tgttctacct tcgcttacaa tattcccagt taaacttgca gaatttgtat ctgcttcttt
    37321 aaaagtataa tattttccgt cagtagtagt catgctactg agttttttat ctgtgacatt
    37381 atagctggta ccaatcagtt gttttttatt ggtaatgtaa gttccgtcac tttctttttc
    37441 tccaattcca gtatcatttt tcaatgatag caaacgccct tgttcatcaa catagcaaac
    37501 tttcacattt tctgagatta gttctgccaa ttctgaggtt tttttctttt tctcttcttc
    37561 gggaatattt agttttggaa tgattttttc aacaacggtt cgtgatggtt ccacaatatc
    37621 ttggatgact gaaaagtcag ctagaattgg gagattatac tgaacacggt gactttgagt
    37681 gtttactcct actctttcat tattctctga aaatacttgt acggtataag aaacaacatc
    37741 ttttcctaat agaacatccc cagtagagaa atagccgcct tttcctagtt tgctatctcc
    37801 agagtccact tctttcctaa tcttatcaga tagtttttta ccagtcagta cattcgttcg
    37861 cacaatccct ttgtctaccc ctacaaagtg ggagaacttt ttgaactctt cagaaccaga
    37921 tctagcccaa ccattattaa gggcatttgc ttttgtattt gtattctctc tcaaaggttt
    37981 ggcgattaga attatattca tcggcactta gagttgctgc tatatctgac tcttgaatac
    38041 caacttcctt actaccattt ctagcggcag tatatgtgta tttatctgtt tctacttcta
    38101 gctgattatc cttaacatga taggtaattt tctcctggta taagagtctt cagtagttta
    38161 tatgctctgt catcatcttt agctttagaa gcagctgagt ttagccaaat tggggtatta
    38221 ggagtatctt tatcagcctg tttcaagaca ttattcaagt catttgctaa cctattggtt
    38281 gtcctcactg tgaaagtttt cttccagtct gaaccacttt tattagactt agatatgctc
    38341 atgaaatcct ggtcaacatt caacacaata tcgccttgtt ttttagcatc ttccgttgct
    38401 tctgcttcaa attgatcatg gagtttttgt tgctctggtg tatagttttt ttatttacac
    38461 gatttaatgt actatttttt attttagtat taagaactcc attaatacga tttttaaatt
    38521 ctgcttcaaa aaatccctta atttgttggt gcgcaagttc aacattcaaa cctttcttat
    38581 acaagtcttc attctgaacg atttcggcta cacggtgaat ggtttgatcg tataccgtct
    38641 tctcttaacc agcagtatcc ttagttttaa tgactactcg ataggttcct ttagaaccgt
    38701 tatagtcatc tagttttaaa aaagcattcc aaacattcaa aaatagttgg aacttccctt
    38761 aataaatccg tcactttctt tttcaagata gcccaagctt gctcaatagg attcaaatcc
    38821 ggtgaataag gtggtagagg taagaaaaag tgtttatctt ggatgcagag ttcatccaaa
    38881 atgttcttgg gatgaaaact agcattgccc atgacaataa catgaggtgt cttcaaagca
    38941 ggtaggagtt gcgttttgaa ccactccaca aagaaatcgc ttgtcatgct tttcttgtaa
    39001 atcatgggag ctataaactc tccgtctact tgtcctgcaa caattgaagt tcgctcaaaa
    39061 cgacgtccgc taatcttttc atagactttc tcccctctag gagcccctgc ataaggacga
    39121 tagaggtagc ggtcgattcc tgtttcgtca atatatacga ttggtaaatt ttttaggtta
    39181 tccaaaatat caagaaactc agcgactttc tctggctctt gttccttaaa gctcgtcatc
    39241 tttttttaaa gtgaccttaa tctgctttaa agctgcccat actgaaggaa cagcacaatc
    39301 aaaatgtgcc gcaatttccc gtaaaaaagc atctggatga gcctctacaa aggctttcaa
    39361 ttcctctaaa ggaatctttc ggtttttgac gactcgcttt ttcctctcta tgtgtccttg
    39421 ttcacatctt tcttttccca cgtgaagaga gttctgacgc caacaccaaa aaacttggct
    39481 gcctcgacat ggctgtgccc ctctttgatg taatctaatg ctcgctgttt aaaatcagta
    39541 ctatatgcca tagctttatt ataatatgct tgtttaaaac taagcaacta tatcaatgtt
    39601 ttgttattag aagacttact ttttttactg aaatcgaatt tttcctaacc tcaacatcat
    39661 ataaccccaa aattcaatct gacctggttt gaagagatgt tcgaagcaga taaggtttta
    39721 ctaaaactaa aaaaaatgat ataatcaaac tgattaaatg ttttaaaaat aaaggagaat
    39781 ttgaatgtct taccaagaaa attaccagaa atgggttgat tttgtggagc ttcctgacta
    39841 ccttcgtcaa gatttggaaa atatggacga aaaaactaag gaagatgcct tctatacaaa
    39901 tcttgaattt ggtactgcag gtatgcgtgg cttggttggt gctggtacaa accgtatcaa
    39961 catctacgtt gttcgccaag ctactgaagg attggctcgt ttgattgagt caaaaggtgg
    40021 aaacgagaaa gaacgcggtg tagcaattgc ctacgatagc cgtcacttct cacctgagtt
    40081 tgcctttgaa tctgcggcag ttcttgctaa acacggcatc aaatcttacg tatttgaaag
    40141 ccttcgtcca actccagaac tatcatttgc agttcgtcat ctcaactgtt tcgcaggtat
    40201 catggtcaca gccagccaca accctgctcc atttaacggt tacaaggttt acggtgaaga
    40261 cggtggacaa atgcctccac acgatgcgga cgctttgact acttatatcc gtgcaatcga
    40321 aaacccattt gcagttgaag ttgctgatgt ggaaactgaa aaagcttctg gcttgattga
    40381 agttatcggc gaagctgttg acatagaata ccttaaagag gttaaggaca taaacatcaa
    40441 cccagccttg attgaagaat ttggtaaaga catgaagatt gtctacacac cacttcatgg
    40501 tactggtgaa atgttggctc gtcgtgctct tgcccaagca ggatttgact ctgttcaagt
    40561 tgttgaagcg caagcaactg ctgacccaga cttctcaact gtaacatctc caaacccaga
    40621 aagccaagca gcctttgccc ttgctgaaga acttggtcgt caagttggtg cagatgttct
    40681 tgtcgcaact gacccagacg ctgaccgtgt tggtgttgaa gttcttcaaa aagatggtag
    40741 ctacctcaac ctttcaggta accaaatcgg tgctatcatg gctaaataca tcttggaagc
    40801 tcacaaaaac gctggaactc ttcctgaaaa tgccgctctc tgcaaatcta tcgtttcaac
    40861 tgacttggta acgaagattg ctgaaagcta cggcgcaact atgttcaacg tcttgacagg
    40921 tttcaaattt atcgctgaaa aaatccaaga attcgaagaa aaacacaacc acacttacat
    40981 gatgggattt gaagaaagct tcggttactt gattaaacca tttgtacgtg ataaagatgc
    41041 catccaagcc gttcttgtcg ttgctgaact tgctgcctac taccgttctc gtggtttgac
    41101 acttgctgac ggtatcgaag aaatctataa agaatatggc tactacgcag aaaaaacaat
    41161 ctctgttact ctttcaggtg tcgatggtgc tgaacaaatc aaagcgatta tggctaaatt
    41221 ccgcaacaat gctccaaaag aatggaacga aacagctatc actgtcgtag aagacttcaa
    41281 ggcacaaact gctactgttg ctgacggtac tgttacaaac ttgacaactc ctccaagtga
    41341 tgtgttgaaa tacacacttg ctgacggttc atggattgcc gttcgccctt caggtacaga
    41401 accaaaaatc aagttctaca ttgcagttgt aggggaaacc aacgaagaat cacaagctaa
    41461 gattgctaac atcgaagcag aaatcaatgc atttgtaaaa taaagaccta taaaagatga
    41521 gaccaaccaa cctcatcttt tttcgtatca aatctaagca attttagaaa ctttatggca
    41581 tactagactt atcaatgaaa gcgaggtaat ctcatggaac aatttttaga taacatcaaa
    41641 gaccttgaag tcactacagt tgtgcgtgcg caagaagctc ttgataaaaa agaaactgca
    41701 accttcttta tcggtcgcaa aacttgccct tactgccgta aatttgcaga tacattgtca
    41761 ggtgtcgtag ctgaaaccaa agctcacatt tacttcatca atagtgaaga accaagccaa
    41821 ctcaatgatt tgcaagcatt ccgctcacgc tatggaatcc caactgtacc aggttttgtt
    41881 catattacag atggacaaat caacgtccgt tgcgactctt caatgtcagc acaagaaatc
    41941 aaagatttcg caggattgta aaaaatcagc taacaagtct taaaatcaca aaaacgcata
    42001 atgtaaggtg caaaaacctt gatattatgc gttttattgt tcctgaaaca gttacatcag
    42061 catttcatta cagaacattt taattttgga agtcaaatca atttttaaca atgttttaga
    42121 aatcacagtg ggctattcca tattcaatta tccatattca atcgctatta tcgttttcct
    42181 agattacaaa aaaactacgt tttgctaatc aaaacgcagt ttcagccact attttatctt
    42241 actgtccttc ttttacttct ttggttgcta catcttctcc aaaccatttt tggctgattt
    42301 cttggaactt gccgtccttg taaagactag aaaaagcttc atttatcttc ttaaccaagg
    42361 ttgtatcttc cttacgggct ccaaccgcaa aagcttctgt ttctagtcca actgtaaaga
    42421 cattataatc gtttaaaaca ccttctgctt ctaaataata gtttgcatag acacggtcaa
    42481 tcaatagacc atcaattcga tcgtttttca aatcaatcaa ggcttcatta aaggtttggt
    42541 attgattcgc ttccttatta gcgacaatat tcttcaaaat ttctggattt gcttcaaagt
    42601 ccgcataacc agatgaacca gcttgagctc ctaatgtctt tccagtcata tcctttgcag
    42661 tcgtgatacc agatgatttc ttcgtaacca atacctgctc attcttcata tatgagttac
    42721 tgaaagccac cttttcacgg cgttcgtctg tagcggaata gccattccaa atcagatcaa
    42781 tcgttccttt tgtcaattca gcttctttca aatcccaatc aatcggttgc caatttaccg
    42841 tgattccgta tttttcaaaa acagctgtag ctaaatcaat atcaaatcct gcataagaac
    42901 catctttctg agcaaatccc attggaacaa aagtactatc aaatccaata gtaatagact
    42961 tgttagactg gtactttgac caattatctc cactagtttc gctagaattt ttcccacaag
    43021 ctactaagaa caaagcagtc atcagactga ctaatacaag catccatttt ttcatccatt
    43081 tttcctccta tttaggttct actttcaata atacatctgc gatattttca gcaaactgca
    43141 aatcatgggt aaccacaatc tgggtcatcc caagttccct attttgcaag attagcttct
    43201 ccacttccaa acgtaattct ggatccaggg cagaagttgg ttcatcgtag ccaatgattt
    43261 ctgggtcaat catcatagca cgcgccaaag ccacccgctg cttttgccca ccagatagtg
    43321 agaaaggata ggcctctgcg tgtcctccta gtcctaactg ttccaagagt ccactcgcct
    43381 tcttctcagc ctcttcctgc ttcattccca tggtcttcac aggcgataaa gtcaaatttt
    43441 ccagaactga tagatgagga aatagttgaa aatcttggaa gacaaatccc agtaggttgc
    43501 gcttctgcaa ttcatctagc tctaaaggtt gtccattata aaagatttgc cctgaatcaa
    43561 tggtttcaag acctgcaagc atacgtaaaa gagttgtctt acctccacca gaaggtccaa
    43621 cgatagccag gatttgcttt tcaggaatac ttagactgaa atcagacagg atttgtttgt
    43681 ctccaaagac tttattgata tttcgtaatt ctaacatagc tgccccctat ctataataac
    43741 tgtacttttt ctcaactttt ttggaaataa ttgtcacaat cccaattaaa atcaagtaaa
    43801 tggctcctgc caagaacata ggaaccagac tagcatcgcg gttagcagct gttcgactag
    43861 ccaagataag gtctgaaatt ccgagagcat agaccaaaga agtatccttg accaaactca
    43921 taacttcatt aaagacacta ggaagaacga tcttggtcac ttggggcaag ataatatagc
    43981 gcactctgtc aaaagggcta aacttcaaga ccttggcagc ctcatactgt cctcttggaa
    44041 tagtgtcaat tcccccacgg aaaatttctg caaagtaagc tgcatagttg agaacaaagg
    44101 caataatagc tgcaggaagg cggtctaaac gaatcccaat acttgggagc acataataga
    44161 taaaaatcag ttgcaagagt aagggggttc ctcgcataac ccagatgtaa atgttaatca
    44221 gataatggag gggcttccaa tggacttgca aggcaaaggc aatcaaaacg cccaagggaa
    44281 tcgaaaatag caagaccagt gcaaagacct gtacagtcgt gctcgcacca ttcagtaaac
    44341 tcggtaatat ctcaaataaa taagacatac tgcacctcct aaaagtaatt gttcctatta
    44401 tagcatgaat aaacaagatt accaagtatt tttgtaaaaa gattctacca tatacaaata
    44461 aaaaccgtag ctatcaaaag agataaacta cagttctata tgtttaaaca ttcttacaat
    44521 ctctcaaaca gttcttgcat ttgcacatca tctggaacca gttttaagta agtgtgagca
    44581 tggacttttg cttcttcaaa atgtcccaat tcacgcaaga gatagatata gtgttccaga
    44641 aattctggat tgtccttcaa atctcctgtc aactcttgat aatgctcata agcagtatcc
    44701 aaatcgtcca tttcttgata agaacgagca atcatccact tggtcaaaag attttctggc
    44761 tcctcactct gcaagtctag aatatcctca taacgctcct gctccagata aatagtggct
    44821 aaacgaagca agatttcttc tgtatcctca gcgtcttctt ttgcagtaag gagataattt
    44881 tctgcaccac tagcatcatg caattcataa gaaaattgtg aagcagctag caagaggcga
    44941 gtttcaaagg gatttttctc taatccttgc ttagcgatac gcagggcttc ttgaacttga
    45001 tgttccttat gtaaagcctg actgtaccca tactcatagc cttcaaagtc aggagaaatg
    45061 gtatcaagct gcttaaagta gagggtggct ttttgatatt cttcttgatc aaaataaaga
    45121 ctggccaact caaaagctgt taagtcatcg tattctaact ccagggcttt ttctaaaaac
    45181 tcagtagccg tttcaaattt ccctaactga gcataggcaa agccaattcg ttgataggtg
    45241 gaaatgcccg tttgctcata aatcgagcga ttatctaact gggcataggc ttgaatagcc
    45301 gcttggtaat tttccaactc actatccaac tctgccaaac ccaatatcaa gagagaatcc
    45361 tctgagtagg tcaaggcctc caataatttc tcacgtgcca catctgtcaa accttccagc
    45421 tggtaaaggt ctgccttcag agccaaagac gagacatacc agtcactgtc agcttggatt
    45481 tcctcaagat aggtaaaggc ttcttctatt tgaccatcct cgctagcaat tgcagctaga
    45541 ttaagatgaa cctctggaaa atcctctaca attttcaggt aaatttcctt ggcctgagga
    45601 tagaaaccaa tcccttcaag ataagttgcc aactcataca gaagatcact tgaatcattt
    45661 tctaaagctt tggcgaaata atgctcagcc ttagttaaat cttgctcctc caaagcctgt
    45721 aacatctgtt gactattgtt cactcttgac ttcctcaccc tctaattcat atagaccact
    45781 gactacctta taccattcga aaatggctga aatgacaacc ttagcagagg cataaaccgg
    45841 aataccaagt aaaactcccc agataccaaa catagatcct gaagttaaca aaacaaagag
    45901 aacattaata gggtggatgt ttaattgact tcccaaaatc aatggagaga caaaacggcc
    45961 ttcaatagtt tgttctacga taaagacaat cactactttc aaaagcatga ctggaccagc
    46021 aatcaaaccc aatactagag caggaagcat ggctagaaag ctaccaagat aagggaccag
    46081 atttaaaata ccagcagtaa cccccagcgt aaccgcatag cgtagaccaa taatcttgaa
    46141 gaagatgata aacattactg ctacaataat agccactgtc acttgccctc gaacatagtt
    46201 ggacaactgt tgattcacat ctgatagaac ttgtccaaca ggttccttca attttcttgg
    46261 aatgaattgg gtcaaatagt tacgcaagcc tttcccatca cgcaagagat aaaagagcat
    46321 gaaaggaacg ataatcaagg caacaatcac ttgagaagcc ccgctaataa aggcactcac
    46381 ccagttgact gcctgagatg aaaccttact tgccaaaact gtagcctggc tagaaaaatt
    46441 ggtcaaaact tgctctaatt gaggtctgaa atcatctggc agatgctggg ctaccaatcc
    46501 attaacaatc ctatctatat cttctaagta aacaggaacg tttcttgcaa aggtcaaaac
    46561 ctgacgttgc agatttggaa tggcgactgc caagccccaa atgataaaga gagcgatgat
    46621 aacaaagaca atagtgatag ctataacacg attaacctta tgcttctcca tccaatcaac
    46681 aataggattc aacaaataat ataacaaacc agacaaaatg actggcaaca tcacaactgc
    46741 taaaaagtct aaaacaggtg aaaatagaaa actaatctta cttaaaataa aaagattcag
    46801 tcccaataat aaggttacta aaaataccgt aattgccttg ttatctaaaa accacttgaa
    46861 aaaccaagat aggctaaaat gtttctcttt ttgctccata aatacttcct ttctattgtt
    46921 ctctcattat accatttttg aaacaaaata actctttttt aaagtgctta catctaattg
    46981 gatatcttta atttacttgt ttttgtgata taatagtctt atctttacac agaggtatag
    47041 taatgaaaga aactgtttat tttggaactt atacacgtcg tacttctcaa gggatttaca
    47101 aggcagactt tgatacagaa actggtcagc tttcaaatct agaacttttt gcagctgagc
    47161 caagtccaac ctaccttgcc tttgaccagc accaacattt atacactgtt ggtagccaag
    47221 acgataaggg gggaattgca gcctatcaaa ctgacgggac tgtgttaaat catgttgttg
    47281 aagaaggagc tccccactgt tatgttgctg tcgatgaaaa gcgtgatttg gtttacgcag
    47341 ctaactatca caagggacaa gtccttgttt ataaacgcca ggaagatggt agtcttctac
    47401 ttagtgatat ggatcaacac agtggccaag gtccacatga aaatcaagct tccccccatg
    47461 ttcactatac agatttaaca cctgaccact atctagtgac ctgcgacttg ggaactgacc
    47521 aagtcatcac ctatgacctc gatcaagaag gaaaattatc taagctctat acctatcaca
    47581 gcaagccagg agcaggctca cgccatatca ttttccataa ccactataaa atcgcttatc
    47641 tcatttgtga actcaatagt actatcgaag ttttaatcta cgatggcgtt ggcgaatttg
    47701 aacgtatgca ggtcatttca actttaccgg aagcttacga aggctttaat ggaaccgctg
    47761 ctattcatct ctctaaagac ggtaaatacc tctacgcttc taaccgtggc catgattcta
    47821 tcgcagtata taccatcctt gcggacggta gcttagagtt attagaaatc gttccaacgc
    47881 atggtcagac tccacgtgat tttgatttga cacccgacca aaaatttctc attgttgtcc
    47941 atcaagactc tgacaatgca actgtcttta aacgtaattg tgacaatggt cgtctagcag
    48001 aactctccaa cgacttccat gttcccgaag cagtctgcat ccgttttgct ccttaaaaca
    48061 ccataaaaaa tgaacttggt attttcaagt tcattttttc ttatagtcta tttccgacat
    48121 taatacggtt aatagcacgt tgcaaagcaa tcttagcacg acgttcttgg tcaatcaaat
    48181 gtttgtcttg tgcttcttca attgcacgtt ctgcacgaag tttggcacgt tctgcacgac
    48241 tgatatcgat atcacgagca cgttctgcag agtcagcgac gattgtgatc atatcattgg
    48301 caatttcaat aacgccaccg tttactgcaa tccagttcac gtgatcttta tcatcgatac
    48361 gttttacctt tacttcatca actgctaaaa ccgcaatcat attttcatgt cgtggcaaga
    48421 tccccatctc accatccaga gttcgaaccg atacatagct ggcatggtga tcatagacga
    48481 gaccatctgg tgtcacgatc tggacagtta actgagccat agatcacctc ttaaaatccc
    48541 attttttcag cttttgcaat cacatcttcg atagaaccta caccacggaa ggcatcttct
    48601 ggcaagtggt cgtatttacc atcaaggatt tccttaaagc cacgtacagt ttcagcaact
    48661 ggaacataag aacctggctg accagtaaat tgttccgcaa cgttgaagtt ttgtgacaag
    48721 aagaactgga tacgacgggc gcgagcaacc aaggtctttt cttcatcaga aagctcatcc
    48781 ataccaagga tagcaatgat atcttgcaat tcatggtaac gttgaaggac acgttttact
    48841 tcagcagcaa ctgcatagtg ctcttctcca acgatttcag gtgccaaggc acgtgagctt
    48901 gaagcaagtg ggtcaacggc tgggtagata cccaattgta ccaacttacg ttccaagttt
    48961 gttgttgaat ccaagtgagc gaaggctgtt gctggcgctg ggtcagtata gtcatccgct
    49021 ggcacataga tagcctggat agaggttaca gaacccttct tggttgatgt gatacgttct
    49081 tgcaattgac ccatttccgt agcaagtgtt ggttggtaac caacggctga tggcatacga
    49141 cccaaaaggg cagatacttc tgaaccagcc tgagtgaaac ggaagatatt atcgataaag
    49201 agaagcacgt cttggccttc cacatcacgg aagtattcag cgattgtcaa accagtaagg
    49261 gcaacacgca tacgtgctcc tggtggctca ttcatctgac caaagaccat ggctgttttc
    49321 tcgataacgc ctgattcttt catttcccag taaaggtcat tcccctcacg agtacgttcc
    49381 ccaacaccag taaatactga aataccaccg tgctcttggg caatgttgtg aatcaattct
    49441 tggattaaga cggttttacc aactccggca ccaccgaaaa gtccaacttt accaccttta
    49501 aggtaagggg caagaaggtc aataaccttg atccctgttt caaggatttc agaagaggta
    49561 gacaactcat caaaagttgg agctttttta tgaattggct gacgctctgc gtcttctgta
    49621 aaaggagctt ccaaatcaat ggtatctccc aaaacgttga agacacgtcc caaagtttct
    49681 ttacctactg gtacagagat tggacgacct gtgtccaata cttccattcc acgagtcaac
    49741 ccatctgttg attccatggc gatagtacga accataccat ctcctaactc caaggctact
    49801 tcaaggacga tttttgtttt tctttcgtca tttttgtaga cgacaagtgc attgttaatc
    49861 tcaggaagtt tttcccctgc tgcaaacaaa acgtctacaa cgggaccgat aacctgagca
    49921 attttacctg aactcatctc cttctcctat tctatataag atactgtcgg ttcctagctc
    49981 aactaggtcc taagttcatt ttcatacgag ctggactaga gcctattcta aggcactagc
    50041 acctgctacg atttctgtaa tttcttgtgt aatcgccgcc tgtctggcac ggttatactg
    50101 aattgtcaaa tcattgatga ctttcttagc attatctgtc gctgtttgca tggctgtcat
    50161 acccgcagca ttctcagctg tcttggcatc gataatggca ccgtaaatca tactttctgc
    50221 aaactgaggc aacaactgct ccagaatttc ttctcggctg gtttccaatt caaaagtcaa
    50281 gctgtactct tcatccgctt catttggatc caagtcaaca atcggaagca tttgttccac
    50341 acgcatttga ctggttagcg tattgacatg gtggttgtag caaacataaa gctcatcaaa
    50401 gagttcattt tggtacattt caacagtttt tgaaataatc ttacgaactt gatcaaagct
    50461 aggttggtct gccaagccac gtaattcata aagtggttga ataccgcgag ccttaaagaa
    50521 atcagctccc atcccaccga tacagatcat ttcaaaacct ttaccgtctg ggtggtattc
    50581 ttctttcaac tccataacag ctttcaaaat agaggaatta taacctccaa ccaaaccgcg
    50641 gtctgaagtg ataacgatat agcctgtctt cttcacagaa cggctaatca acatcggatt
    50701 agttgaagca ccagctccat taccatgaag gatatctgtc aaaagtttac gcactttctg
    50761 agcgtaaact tggaagttgc gagcagcttc ttcagaacga cctagcttag cagccgatac
    50821 catttgcatg gcattagtga tttgactcgt attttttgtt gaggcgattt ttgttttaat
    50881 atcatttaga gatactgcca tctgacacct ctattcttat tggaagctag attgattgag
    50941 aaactctgta atcgcagcat ccaagactgc ttcttctggc aagtcttttg tatcacgaat
    51001 ggtttccaaa atctctggat gttgagcatc aaagaaggta tggaactctt cctcgaaacg
    51061 aacaatatca tctactggaa cagtatccaa gaaaccatgt gtcaaagcat aaagaatggt
    51121 tacttgtttc tcaacaggta atggtttgtg aacaggttgt ttcaagacct caacggtacg
    51181 acgtccacgg ttcaacttag cctgtgttgc tgcgtccaag tcagaaccaa acttagtaaa
    51241 ggcttccaac tcacggtatg aagcaaggtc gatacgaagt gtaccagcaa ccttcttcat
    51301 ggctttgatt tgtgcagaac cacctacacg agatacagat gaacccgcat cgatggctgg
    51361 acgaatacct gcattgaaga ggccatcgcc aaggaagatt tgtccatcag tgatagaaat
    51421 cacgttggtt gcgatatagg ctgagatatc tcctgcttgt gtctcgataa atggtagggc
    51481 tgtaattgat ccaccaccaa gttcatcaga aactttagct gagcgctcaa gcaaacggct
    51541 gtggagatag aaaacatccc ctgggaaggc ttcacgacct ggaggacgac gaagcaagag
    51601 cgatagttca cgataagcta ccgcttgttt tgatagatca tcgtatacaa tcaaaacatg
    51661 cttaccttga tacataaatt cttccgccat agcaacccca gtataaggag ctaggaagag
    51721 caatggagat ggttgtgaag cagaggctgt cacaacgatt gtgtagtcca aggcaccgta
    51781 ctgacgaagt gtttctactt gcgtacgaac tgttgattct ttttgtccaa tcgcgacgta
    51841 gatacagatc atatcttgat ctttttggtt caagattgta tcaatcgcaa tggttgtttt
    51901 ccctgtctga cggtcaccga taatcaactc acgttgacca cgaccaatcg gtacaagggc
    51961 gtcaatagct ttcaaaccag tttgcaatgg ttctgaaaca gacttacgtt gcataacacc
    52021 aggagctggt gcttctactg gacgagtttt atcagtgtgg atttctccaa gaccgtcaac
    52081 tggacgacca agcggatcca caacacgacc aatcagactt tcacctacag ggacttccat
    52141 gattttccct gtacggcgga ttgtatcgcc ttcacggata tctgtaaagt cacctaggat
    52201 gataatacca acgtctgttg actccaagtt ttgagccata ccataagagc cgttttcaaa
    52261 attcaacaac tctccactca tgacattttc aaggccatga gcacgcgcga taccgtcccc
    52321 gatataggtt acaacacctg tttcagtcac atcaaaattg ggtttgaaat tttcaatttg
    52381 ttgcttaatt aaagcgctga tttcttgtgc gttaattgcc aaaagaacac cactttctat
    52441 ttcaaatttt ctttaacaac tttaagttgt tgtttaatac tcacatcaat tgtcttgtga
    52501 ttggcaaaaa tgacaaaacc accaatgaga ctttcatcga tttgttcttt tacactcctt
    52561 actttcagag acattttttt ctcaatcaaa gggagcaaac gagtcttctg ttcatcagtt
    52621 agaggatgag cagacgtaat cgtcacttca aatcgatttg tttctttttc aagtcggttc
    52681 aagcaatcta caagcacatc ataaaaaaga tttgctctgt gattgtaggc cagaacctgg
    52741 ataaagtttt gtaataaagg cgacacagaa tcttggaaaa aagcaattgt tttttcctta
    52801 tccgactcgt ctactgccac ttgttttaaa aaagaaggca gacctgtttt ttcaacaact
    52861 tgcttgattt gagtcaagtc tgaaaagata cggtcttctt ctcctttttc aagtaccaat
    52921 tggacaaaag gcatgctgta tttttcaatt acctttactg ttttcttgtc cattaagctt
    52981 ctcctagctg atcgatatac tgatcaatga gtgctttatg ggcatgactg tcaaggtttt
    53041 gtgagatgat tttaccagct aagctgatgg tcaaatctgc gacctcaccc ttaacactct
    53101 gtaaagcttc tactttattt tgagcaattt cttgattggc tttttctttt aagtgtcctg
    53161 cttctagttt agcatctgct aagatattag ccttactttg ctcagctgtt tcctttgcat
    53221 tttcaatgat tgtcttagct tctttacggc taccagccaa ttcatcttcg cgtttttgag
    53281 ccaatacttc tgctttttga cgggcttctt cagctctgtc aatatctgaa gcaatttttt
    53341 cagctctttc ttcgaaaatg cctgtaatat tagaccatgc aaatttttta atcaagacta
    53401 gcaaaagaat aaaagagcca gtgattaaaa taaaattacc aattaattca cctactgtta
    53461 cgtgcatcag ttactccttt ctattcctct tcaatattaa tcttattccc taaatacaca
    53521 gatgtcaaaa gagtaaaaac ataagcttgg atgcaggaaa taaagacaga aaatgcagtc
    53581 caagccaaat tagctccaaa ggctactgga taccaataaa tagcttggtg ggaaagaaga
    53641 agtaacaaac tcgtcatgac ctctcctgca aagatattcc caaaaatccg caaagccaaa
    53701 gataagaagt ttgtaaattc ttccaagata ttcatcggta tgacaaaaac aggactcata
    53761 aaagatttta tacttttttt aaatccacga cgacgaacgc tttctatatg tgtcaacaaa
    53821 atgacaagaa aagataaggt taagtcatac ggtaaattag cggttggcga actccaccag
    53881 ttagtcccat cgatcgtttg aagctttgtc attaagccaa ggttattggc aatcaccatg
    53941 aaaaggaata aacaaaggaa aaagagtgag taatctttca tgtagcgcga accaatgtta
    54001 ggttctgtaa atccaataac aaagtcatag acatactcaa gtacattttg ctttcctttg
    54061 ggtttcaagg tcatattgcg gcttgcccaa taaataaaga caaaaataac tcccacaatc
    54121 aacaaagtca tggctaacat agtcagattg aagataacag gaccaataga gatgattgga
    54181 ttaatacttt cttccatcta aaatcctccc ttttcttctc gttccatgta tttatttgat
    54241 aataaatgag aagacaagag ttacaaagaa agttccttca ataaaggcaa cacctaaaaa
    54301 catcaaacta cgaaactcag aaagcatatc tggttggcgt gctactgatt taaacagtcc
    54361 attcatcaat aaaccttcac cgacagatac gcccatacag gcaatacata agcctaaaaa
    54421 tgttaaattc ataacaaatt ctcctttaaa ataaaattta cttacttagt gtagtcctaa
    54481 aatttaaatt tgtcaacttt taaccgctat tggaagcgtt taataaaaat tatttccatt
    54541 ttgctaaatt tcaagttcaa gttagccatc cagaagtctt ctctgggtga cttgtagtcc
    54601 aagcattttt taggatagtt gttaatccac ttttcgatga atgcgacttc tttgggagtc
    54661 attttcttgg ttcccttagg taaccatcta cgaatgaacc tgttgtgatt ctcattagtt
    54721 cccctttccc aaaaggcata ggggtgcgca taataaatgt gctcctcaga aaatacatca
    54781 aacaagcgat tgaattccgt tccattatct gccgtgatgg aaagaatctt gtgttgtttt
    54841 aagatgagtt ttagagcctg attgaccacc tcagcacttt tatttggaat caatcggatg
    54901 atctgatgtc tactctttcg atccgtcaag acaagcaagc agtagttttt cgctctcgta
    54961 agtagaaccg tatcaatctc ataatgccca ttctccaagc gaagattgat agcttcagac
    55021 cgctgttcga tggattgacc agcaggttta aagttggtgc tagcctgttt cttaagcgct
    55081 tttccttttc tagggtaaag cagatcctg
//
LOCUS       DAVLDI010000004        54965 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLDI010000004 DAVLDI010000000
VERSION     DAVLDI010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54965
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.004"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            360..947
                     /locus_tag="VXD01_000239"
     CDS             360..947
                     /locus_tag="VXD01_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600702.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(1034..1237)
                     /locus_tag="VXD01_000240"
     CDS             complement(1034..1237)
                     /locus_tag="VXD01_000240"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600703.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(1534..2238)
                     /locus_tag="VXD01_000241"
     CDS             complement(1534..2238)
                     /locus_tag="VXD01_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV0600704.1"
                     /translation="MMSELFGEFLGTLILILLGNGVVAGVVLPKTKSNSAGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEVEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(2306..4132)
                     /gene="glpO"
                     /locus_tag="VXD01_000242"
     CDS             complement(2306..4132)
                     /gene="glpO"
                     /locus_tag="VXD01_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV0600705.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVKAALAQNDLAELKN"
     gene            complement(4174..5682)
                     /gene="glpK"
                     /locus_tag="VXD01_000243"
     CDS             complement(4174..5682)
                     /gene="glpK"
                     /locus_tag="VXD01_000243"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV0600706.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(5841..7268)
                     /locus_tag="VXD01_000244"
     CDS             complement(5841..7268)
                     /locus_tag="VXD01_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0600707.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            7433..8305
                     /gene="hslO"
                     /locus_tag="VXD01_000245"
     CDS             7433..8305
                     /gene="hslO"
                     /locus_tag="VXD01_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV0600708.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            8292..9272
                     /gene="dusB"
                     /locus_tag="VXD01_000246"
     CDS             8292..9272
                     /gene="dusB"
                     /locus_tag="VXD01_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV0600709.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLID
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(9502..11652)
                     /gene="pspC"
                     /locus_tag="VXD01_000247"
     CDS             complement(9502..11652)
                     /gene="pspC"
                     /locus_tag="VXD01_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV0600710.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGST
                     QAATSSNMAKTEHRKAAKQVVDEYIEKMLREIQLDRRKHTQNFAFNMKLSAIKTEYLY
                     GLKEKSEAELPSEVKAKLDAAFEQFKKDTLKLGEKVAEAEKKVAEAEKKAKAQKEEDR
                     RNYPTITYKTLDLEIAESDVEVKKAELELLKEEAKTRNKDTINQAKAKVESKQAEATR
                     LKKIKTDREQAETTRLENIKTDRKKAEEEAKVKAKPKKRTKRGALGEPATPDKKENDA
                     KSSDSSVGEETLPSPSLKPGKKVAEAEKKVEEAEKKAKDQKEEDRRNYPTITYKTLEL
                     DIAESDVEVKKAELELVKEEAKESRDKEKIKQAKAEVESKKAEATRLEKIKTDRKKAE
                     EEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPTEEPENPAPAPKPEKPAEQPKAEKP
                     ADQQAEEDYARRSEEEYNRLTQQQPPKIEKPAPAPQPEQPAQPSTPKTGWKQENGMWY
                     FYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGS
                     WYYLNANGSMATGWLQYNGSWYYLNANGDMATGWFQYNGSWYYLNANGDMATGWLQYN
                     GSWYYLNSNGAMVTGWLQNNGSWYYLNANGDMATDWVKDGDTWYYLEASGAMKASQWF
                     KVSDKWYYVNGSGALAVNTTVDSYRVNTNGEWVN"
     gene            complement(11731..12258)
                     /locus_tag="VXD01_000248"
     CDS             complement(11731..12258)
                     /locus_tag="VXD01_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV0600711.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LVHIVFYLSCLVEAMVHKTMFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(12353..13684)
                     /gene="hk06"
                     /locus_tag="VXD01_000249"
     CDS             complement(12353..13684)
                     /gene="hk06"
                     /locus_tag="VXD01_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV0600712.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(13681..14334)
                     /gene="rr06"
                     /locus_tag="VXD01_000250"
     CDS             complement(13681..14334)
                     /gene="rr06"
                     /locus_tag="VXD01_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV0600713.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(14655..17087)
                     /locus_tag="VXD01_000251"
     CDS             complement(14655..17087)
                     /locus_tag="VXD01_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0600714.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVSAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(17089..17547)
                     /locus_tag="VXD01_000252"
     CDS             complement(17089..17547)
                     /locus_tag="VXD01_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV0600715.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            complement(17666..18394)
                     /locus_tag="VXD01_000253"
     CDS             complement(17666..18394)
                     /locus_tag="VXD01_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0600716.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            complement(18394..19401)
                     /locus_tag="VXD01_000254"
     CDS             complement(18394..19401)
                     /locus_tag="VXD01_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0600717.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(19440..20198)
                     /locus_tag="VXD01_000255"
     CDS             complement(19440..20198)
                     /locus_tag="VXD01_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0600718.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            complement(20161..20451)
                     /locus_tag="VXD01_000256"
     CDS             complement(20161..20451)
                     /locus_tag="VXD01_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV0600719.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETPH"
     regulatory      complement(20524..20626)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(20709..22055)
                     /gene="cbpD"
                     /locus_tag="VXD01_000257"
     CDS             complement(20709..22055)
                     /gene="cbpD"
                     /locus_tag="VXD01_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV0600720.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGHSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     gene            complement(22144..22410)
                     /locus_tag="VXD01_000258"
     CDS             complement(22144..22410)
                     /locus_tag="VXD01_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600721.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(22412..23764)
                     /gene="dnaB"
                     /locus_tag="VXD01_000259"
     CDS             complement(22412..23764)
                     /gene="dnaB"
                     /locus_tag="VXD01_000259"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV0600722.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(23808..24260)
                     /gene="rplI"
                     /locus_tag="VXD01_000260"
     CDS             complement(23808..24260)
                     /gene="rplI"
                     /locus_tag="VXD01_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV0600723.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(24257..26230)
                     /locus_tag="VXD01_000261"
     CDS             complement(24257..26230)
                     /locus_tag="VXD01_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV0600724.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNIQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            complement(26366..26914)
                     /gene="raiA"
                     /locus_tag="VXD01_000262"
     CDS             complement(26366..26914)
                     /gene="raiA"
                     /locus_tag="VXD01_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV0600725.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(26994..27656)
                     /locus_tag="VXD01_000263"
     CDS             complement(26994..27656)
                     /locus_tag="VXD01_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV0600726.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(27653..28951)
                     /locus_tag="VXD01_000264"
     CDS             complement(27653..28951)
                     /locus_tag="VXD01_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0600727.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            29007..29642
                     /locus_tag="VXD01_000265"
     CDS             29007..29642
                     /locus_tag="VXD01_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV0600728.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            29927..30853
                     /gene="cysK"
                     /locus_tag="VXD01_000266"
     CDS             29927..30853
                     /gene="cysK"
                     /locus_tag="VXD01_000266"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV0600729.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVYAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDSIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEFEV"
     gene            complement(30974..32014)
                     /locus_tag="VXD01_000267"
     CDS             complement(30974..32014)
                     /locus_tag="VXD01_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV0600730.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            complement(32093..32872)
                     /gene="rpsB"
                     /locus_tag="VXD01_000268"
     CDS             complement(32093..32872)
                     /gene="rpsB"
                     /locus_tag="VXD01_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV0600731.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            complement(33096..34274)
                     /locus_tag="VXD01_000269"
     CDS             complement(33096..34274)
                     /locus_tag="VXD01_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV0600732.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINIVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            complement(34368..34862)
                     /gene="mreD"
                     /locus_tag="VXD01_000270"
     CDS             complement(34368..34862)
                     /gene="mreD"
                     /locus_tag="VXD01_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV0600733.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            complement(34862..35680)
                     /gene="mreC"
                     /locus_tag="VXD01_000271"
     CDS             complement(34862..35680)
                     /gene="mreC"
                     /locus_tag="VXD01_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV0600734.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            complement(35739..36533)
                     /locus_tag="VXD01_000272"
     CDS             complement(35739..36533)
                     /locus_tag="VXD01_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0600735.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            complement(36526..37365)
                     /locus_tag="VXD01_000273"
     CDS             complement(36526..37365)
                     /locus_tag="VXD01_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0600736.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPNQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            complement(37350..38177)
                     /locus_tag="VXD01_000274"
     CDS             complement(37350..38177)
                     /locus_tag="VXD01_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV0600737.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            complement(38174..38719)
                     /gene="pgsA"
                     /locus_tag="VXD01_000275"
     CDS             complement(38174..38719)
                     /gene="pgsA"
                     /locus_tag="VXD01_000275"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV0600738.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            complement(38730..39551)
                     /locus_tag="VXD01_000276"
     CDS             complement(38730..39551)
                     /locus_tag="VXD01_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0600739.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            complement(39593..40876)
                     /locus_tag="VXD01_000277"
     CDS             complement(39593..40876)
                     /locus_tag="VXD01_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0600740.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSIGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            complement(40873..42123)
                     /locus_tag="VXD01_000278"
     CDS             complement(40873..42123)
                     /locus_tag="VXD01_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV0600741.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            42282..42650
                     /gene="yaaA"
                     /locus_tag="VXD01_000279"
     CDS             42282..42650
                     /gene="yaaA"
                     /locus_tag="VXD01_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV0600742.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            42653..43750
                     /gene="recF"
                     /locus_tag="VXD01_000280"
     CDS             42653..43750
                     /gene="recF"
                     /locus_tag="VXD01_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV0600743.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(43801..45279)
                     /gene="guaB"
                     /locus_tag="VXD01_000281"
     CDS             complement(43801..45279)
                     /gene="guaB"
                     /locus_tag="VXD01_000281"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV0600744.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(45431..46456)
                     /gene="trpS"
                     /locus_tag="VXD01_000282"
     CDS             complement(45431..46456)
                     /gene="trpS"
                     /locus_tag="VXD01_000282"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV0600745.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            46662..48284
                     /locus_tag="VXD01_000283"
     CDS             46662..48284
                     /locus_tag="VXD01_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0600746.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            48346..50898
                     /locus_tag="VXD01_000284"
     CDS             48346..50898
                     /locus_tag="VXD01_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV0600747.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPISYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(50928..52105)
                     /locus_tag="VXD01_000285"
                     /pseudo
     CDS             complement(50928..52105)
                     /locus_tag="VXD01_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            52212..52754
                     /locus_tag="VXD01_000286"
     CDS             52212..52754
                     /locus_tag="VXD01_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV0600748.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(52795..52868)
                     /locus_tag="VXD01_000287"
     tRNA            complement(52795..52868)
                     /locus_tag="VXD01_000287"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52832..52834),aa:Asn,seq:gtt)
     gene            complement(52874..52945)
                     /locus_tag="VXD01_000288"
     tRNA            complement(52874..52945)
                     /locus_tag="VXD01_000288"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52910..52912),aa:Glu,seq:ttc)
     gene            complement(52997..53749)
                     /locus_tag="VXD01_000289"
     CDS             complement(52997..53749)
                     /locus_tag="VXD01_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0600749.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(53746..54870)
                     /locus_tag="VXD01_000290"
     CDS             complement(53746..54870)
                     /locus_tag="VXD01_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0600750.1"
                     /translation="MGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNFLSVTFSSIT
                     GDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKKVFFALLLLH
                     IVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIALKQKKFEQK
                     HLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEVLVKANHKLR
                     SDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIELLDLVRIMS
                     VLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFALGFSTKGRN
                     RGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
BASE COUNT        16581 a        11939 c         9243 g        17202 t
ORIGIN      
        1 acgtctattt attttttatt gttttttatt gtagagcaga cccaagcgaa tgaacatagg
       61 ttgtaaaaag caaatgaaaa aactgcgagg ataatagctt ctgtgtctaa ataacccatt
      121 tcgagacctc ttttcaacaa caacaagcct gtagtttcga taacgatcaa acataaaaat
      181 atataaaaaa ttttcgcatt aagcatattg ttaccgcttt ctttttattt ggttttattg
      241 tataataaaa gttgaaaaaa atcaaaaata caaaggagtt tccgttatgt ctaagatgtt
      301 taaatgcatg tgtttgctag ttatgtctgt tttctgtatg tctagcattt ccccgtcgct
      361 tgtttgtttt tgctgatgat agcttatcgg caaactctaa agttgtatct ggtgaggctc
      421 agtttgagaa tggctcatca gtgcggttcg gagatacgca agtaaatatt ttaagcgatg
      481 aagttcttga ggttgtcaat ccagatggaa gtgtagacac tattgaacga cgtgctgacg
      541 gcgtctatat caatggggca ttttatatgg cttatcaaaa gaatgaaatc gacctaaata
      601 tatcttttag atcatacgat cctaatgttt ggaattacgt caacacaata catgggaata
      661 aacaagctaa cacattcgct aacttcatga ctggtgctgg aatcagttat atgattggta
      721 ggataggtgc tttattgggg ggtccatggg gtgcaataat tggtggagca tattttggta
      781 tacaagctta tcagtcttac ttggattcac aaagcccata tccatactac ataacaagta
      841 cttatatcca tgttgctcaa agaaaatgga agtttatcac tgaatactat agaaactcaa
      901 actatactgg gtatgtaaaa accgtaacaa cctacgtgaa tttctaaaat ataaaccctg
      961 cctagatata aaggcagggt ttatatttta gttaattgct caagtaattt gtaagcataa
     1021 tacttgcgaa actctatttg ttcaagcggt tcaaaagctc ttgtttttta ccctcaagct
     1081 cagctctcct ttgctcgatt tcttcacgtt tttgggcgat ttctgcttgc gcctcgggag
     1141 tttccaaagt gccttgtgac ttgtgaaatt ctactagcat atcaacgatt tttgggtcta
     1201 attcgttgac ataatcagga tttgaccatt tcggcacgtt gcttgcaggt gcttgctttt
     1261 tgccgccttt tttgggcgtt ttggcttgtt gttcagcttt ctgactgtag ttgacctcgt
     1321 ggaattttcg tgcttgatat gatgcgtttt attatgagaa gatttacttc attttttgct
     1381 gaaattgggc tcttgcccaa gctctatcaa aataattgtt ttctaatact caatgaaaat
     1441 caaagagcaa actaggaagc tagccgcaag ctgtacttga gtacggtaag gcgacgctga
     1501 cgtggtttga atttgatttt cgaagagtat aaactagaaa agtgagaata caagcactgc
     1561 caaggctgct ccgataacag ggcctacaac aggaatccaa gcgtaagacc agtctccgtc
     1621 tcccttgttt ggaattggca agatgctgtg catgatacga ggtccaaggt cacgagctgg
     1681 gttcaaggca taacctgttg tcccacctag tgatagaccg ataccgacaa tcaaagttcc
     1741 cactgcaaag gttccgatac ctgcctgaaa atcgtaaaga cccaaagcaa agattgtcaa
     1801 caccaaaaca aaggttccaa ggatttcgct aatcaagttt gatacagtat ccttgatggc
     1861 tggtccagta ctgaaggttg ccaggatatt gcctgcattt tcttctacct cataatgcgg
     1921 tttgaattgc aaccaaacca aaatctgacc cagcatggcc cctgcgaact gggctaagat
     1981 ataaggcaaa acggaagccc aaggcaaacc accttttaag gccacaccga tggtcacagc
     2041 tgggtttaaa tgagctggac tgagcttgcc agatacaaat actgcaaccg caactgcaat
     2101 cccccaaccc atagtaatca caatccaacc tgcactgttg ctcttggttt ttggaagaac
     2161 cacacctgca acaacaccat ttcctagaag aatcaggatt aaagtcccta aaaattctcc
     2221 aaataattca ctcatcattt ttctgtctcc attaaaaaag gggcgggcga caaggattgc
     2281 taccctccac ctcttttatt ttttcttaat tttttaattc tgctaagtcg ttttgagcaa
     2341 gagctgcttt tacatcagca cggtaagttg ctttttcttc ttctgtccag tcatagaatc
     2401 gtcccatttc atccaaaact ggctcaacga tactatccaa gctatcacgc ataaagagca
     2461 tgtgattggt acgacgaaga aggaagtcaa ctgggctaag agtcaactca ttgcgcattg
     2521 catagtgaag agacaaggtg tctgctaagc taagacctgg cgcttgttcc aagctgtgag
     2581 caagtgcaaa gaccttcggt gcatttgaac cataaagatt tgctaggtaa tgagcttcct
     2641 tgctatccaa accacgtgaa actccaagtt gcgcaaaggc ttcgatttct gaatccacat
     2701 ttgctgggtt caattctcca cctgaaacag ggtaagtttt agaattgatc aatttaaagc
     2761 tacggtcaaa ttctgctttg aggatgtcaa ccacgcgctc catagctcct tcagccatct
     2821 tacggtagtc tgtgatttta ccaccagcaa gagtcaaaag accattgtca tcacggtcca
     2881 agctagaccc acgagaaact gcagatggat ccaaatattt ctcagatgtg ctactttcaa
     2941 gcttgctgac agcagactca acatcttcac gtgttttttc tttggagaga taagattcaa
     3001 cagtcgcaat caagttgtca aagctttcat cactgatggt accgttattt ccaccattat
     3061 agtcagaggc actgttccct gcaatcaatg gacgaagacc tgcccagctg ctttcgatat
     3121 catcaatggt gatgttggat tctggaaagc ggttgttgac aatgccaagt agataatcta
     3181 catcttcttg agttactttt ggatgctcca aatcacctgt gtagtctgta tcagttgtac
     3241 caaagtaagt cttgttttca cgtgggagaa caaagaccat acgaccgtca cccaaacctg
     3301 tgtcaaagta aactggctgt gaaaccttga ttttgcttga atccactacc aagtgaactc
     3361 ccttagttgg gcgcatttgt gagaattgcg ttcccttatt agacaaatta cgtactttat
     3421 cactccaagg acctgttgta ttaataacca gacgggcctt gatttcaaat acttggtctg
     3481 tcaagagatc acgagctaca acacctgtaa tcttgccact ttcgtcaaag aggaagcctt
     3541 ctgccttcac gtggttggca atgagggcac cgtcttggtt ggcacgtttg atgttttcaa
     3601 tcacgagacg cgcatcgttg ttacggaagt caagatacac tccacctcct accaagcctt
     3661 ccttcttcaa gtttggctgg cgttccaaga cttgatcctt gctcaaaacc ttgttcgcag
     3721 ttggtgtgtt gctcacacct gctaaaaggt cgtacaagtc catggctact ttaagacgga
     3781 agaggctaaa ggttgctcca tcttcatcgt aaactggtaa gagcattgga tctggttttg
     3841 gaatgtgtgg agcgatttgt tgaaccactg cacgttcaga aaccgtatct gagaccacct
     3901 ctacgtcaaa ttgtttgagg tagcgaagac ctccgtgaac caattttgtt gaacgactag
     3961 atgttccttc tgcaaagtct tgcatttcaa tcaaaccagt ctcaagaccg ctagctgccg
     4021 cctgcaaggc tacaccagct cctgtgattc ctccaccgat aatcaagagg tccagggtgc
     4081 gttcctgcat ttttttaatt gacaattcac gtgttttctt tgaaaattcc atatttacac
     4141 actttctaaa taaatcgctt tattctgcca gtattagtcg tctacttccg caaagacttg
     4201 agttgctttc acagccttct tccagccctt gtagagttgt tccttgcgag attcgttcat
     4261 agatggctca aagagttctc ctgtctcgtt caagagtttc aactcgtcca agtctttcca
     4321 gtaccctact gacaaacctg ctaggaaggc cgctcctaga gctgttgttt ccaggttttt
     4381 agcacgtgca atatcaatgc ctaaaatatc cgcctggaac tgcatgagga agttgttcat
     4441 ggctgcacca ccatccacct tcaatacttg aatggcggtc tgagtatcca cttgcatggt
     4501 gtcgatgatg tcacgcactt gataagcaat agattgcaaa gtcgccttga taaagtcttc
     4561 tttgcttgtt ccacgagtca aaccaaagac ggaaccacga gcattttggt tccagtatgg
     4621 agcgcctaga cctgtaaagg ctggaacgac ataaacttca tcgttgttgt gagaatcacg
     4681 agcgtatttt tcagattctg gtgaattttc aaccatgcga agaccgtcac gaagccactg
     4741 aatagcactt cctgcgatga agatagaacc ttccaaggca taataaacct taccgttgat
     4801 tccgtaacca atggttgtca agaggttgtt ttcagacaac tgcatctctt ccccagtatt
     4861 catgatgatg aaagagcctg ttccataagt attcttaacc atacctggct caaaagccaa
     4921 ctgtccaaag agggctgctt gttggtcccc agccatacct gagattggca cctctccacc
     4981 gtagaaatgg aatggagctg tcttgccgta gatttcggag ttagaacgaa cttctggaag
     5041 tatagccttc ggaatgttaa ggatttccaa aatctcatca tcccatttga gttctttaat
     5101 gttataaagc atggtacgag ctgcatttga gtagtcagtc acgtgagccg caccgtcagt
     5161 caatttccaa accaaccaag tatcgatagt accaaagagc aattcccctt tttctgctcg
     5221 ctcttgagcg ccttctacat gatccaaaat ccaacgaacc ttggtagcag agaagtaagc
     5281 atcaataatc aaaccagtct tttcatggaa tttttccaca taaccttggc tttttagttg
     5341 ctcagccaaa ggtgctgtct ggcgtgactg ccaaacgata gcattgtaga taggaagtcc
     5401 tgttttctta tcccagacaa ccgttgtttc acgttggttg gtaatcccga ttgcctcgat
     5461 ttgatttggc ttgacaccac tttcgatgaa agcacccgca ataactgact gaacagagtt
     5521 ccaaatttca ttggcattgt gctcaaccca acctgcctga gggaaaatct gggtaaactc
     5581 tttttgactc gagctaacct tttccccttt tttgttgaaa atgatggcac gagaacttgt
     5641 agttccctgg tcaatggcca tgatgtattt ttcttgtgac atgtactgtc ctcctgataa
     5701 agatcttgag gtgtttcctc tttacactta ctagtataca aaataaagcg ctttcttgtt
     5761 tatcaacttt ttttaatttt taaaaaaatg tgaggagatt gtgtgaattt cacaaaaaag
     5821 acctggatta accaagcctt ttaagtgaat aataactgac gaatccctgc caaatcttcc
     5881 atatccaagt cgttttttaa ataatagact ggtgtctgtt ccttcttatg aatcgggtta
     5941 ttggtaacca gcaaatcata atgccgacta gggtcataag cttcaatggt aataaaacga
     6001 ttgtattcca aataccgttt caaaatggct gccatccttg aaaagacaag aaaaccagat
     6061 gtcaaatcca gaccaatccg catatgctga ccaccgtttt cagccatata ttcgattaac
     6121 tggagccatt cccagagaat cttcttatct aaatctgtcc cctgttgaaa agcaggtaga
     6181 gcatgaaaaa tctcctctgc tgtctcttta aaatcatgtt ccatcagtaa atatggatga
     6241 cgattctcta actggtactt gtagcgatcc tgtaaaatat agcccttata gagatagact
     6301 tgagcacaaa gctgactgag ttcataggtg acatggtcct ctgtataatc ccccaatagt
     6361 tcctccttct tcatttcttg aatcaattgc gtcagtaaat ctgccaactg ccctccaaaa
     6421 ccaagaatat actccatagt atgaagagga agaatgcgat gagataggag aaaagagaag
     6481 aatatcatca tctcaccatc ctcaactcct agtggaatat gttgcccagc aaaaaaggac
     6541 ggaacctttc tcagcaaacg aagataaaag atattgtcaa aataccctcg cattttctct
     6601 tctatgactt gaaactgaca agcattgacc cgaagacgtt gttgactgat gtgagcccag
     6661 agaaccaagt ccaatttctg ccccacagac aaacttgcac cgcagatttc ctctaaattg
     6721 gcaatctcct gttttctctc tggtttctgc atgtgacctt cccattcctg actcgaccag
     6781 acctttcgga aaagacagaa atagaaatag cgaatctgat gctctggacc tcgccaacgt
     6841 ccattttgga tggataaatc aaattctgac aaaatctgat ttaaaccagc caagtgacga
     6901 ccaagcgtag cctcgctaat caccaattct tgagccagct gatgggctaa aaactgttgg
     6961 tggtagagaa gataaaccaa aatctggtat ttaacagcac tctccaaaaa caagctccga
     7021 atatctctcc ccttggtagc tgcaccgata gacagacgca gattttcatc ttctgagtga
     7081 atagtcagct ctaagccact atccaaagcc ttgtcattga gcagggtgac atatttggtt
     7141 agggttgctt ttgaaaatcc tgtttcttcc attacagcct tgacggtcgt ctgagactct
     7201 tgtaatagaa aggaaaggat tgaaaattga ccacactcgg ctttctccat caaatctcct
     7261 aaatacattt gttacccctt tcattttcta ccttaagcat agcataaatc ttacaaatgc
     7321 taaaataatc tgtttctctt tttattttca tgctgatttc ctggtccatt atcctgaaaa
     7381 tcagtaaaca cacggctccc cctttgggca tttttatgct aaaatagtag ctatggataa
     7441 aattattaaa actatatcag aaagcggagc ctttcgtgct tttgtccttg atagcacgga
     7501 aaccgtccgc actgctcaag aaaaacatca aacccaagct agctcaactg tagcgcttgg
     7561 tcgaactctt atcgccagcc agattctcgc agccaatgaa aaaggaaata ccaaacttac
     7621 agttaaggtg ttgggctcta gctctctagg tgctattatc accgtcgctg ataccaaggg
     7681 gaacgtcaaa ggctatgttc aaaatcctgg tgttgacatc aaaaagactg cgactggtga
     7741 agtcctagtc ggaccttttg ttggaaatgg tcaattcctc gttatcacag actacggtac
     7801 tggaaatcct tacaactcta taactcccct catctctgga gaaatcggtg aagaccttgc
     7861 cttttacctt actgaaagcc aacaaacgcc ttcagcggtc ggcctcaatg tccttttgga
     7921 cgaggaagac aaggtcaagg ttgcaggtgg tttcctagtt caagtcttgc caggagccaa
     7981 gaaagaagag attgctcgct ttgaaaaacg catccaagaa atgccagcta tctctactct
     8041 tctcgaaagc gacgaccata tcgaagccct cctcaaggct atctacgggg acgaagccta
     8101 caagcgtctt tctgaagaag aaatccgttt ccaatgtgac tgtagccatg aacgctttat
     8161 gaacgctctt gccagccttc caagctcaga cttacaggaa atgaaagagg aagaccacgg
     8221 ggtagaaatc acttgtcaat tctgccaaac tacttacaac tttgatgaaa aggacctgga
     8281 ggaactcatt cgtgacaaat cttaatacac cttttatgat tggcaatgtt gagattccca
     8341 atcgtaccgt tttagcgcct atggctggcg tgaccaactc agcctttcgt accatcgcaa
     8401 aagagctcgg agctggactc gttgtaatgg aaatggtctc tgacaaggga atccaataca
     8461 acaacgaaaa aaccctgcac atgcttcata tcgatgaggg cgaaaaccct gtctctatcc
     8521 aactttttgg tagcgatgaa gacagcctag cacgcgcagc agaatttatc caagaaaaca
     8581 ccaagaccga tatcgtcgat atcaacatgg gctgccctgt caacaaaatc gtgaagaacg
     8641 aagctggtgc tatgtggctc aaggatccag acaagattta ctccatcatc aacaaggtcc
     8701 agtctgtcct tgatatccca cttactgtca aaatgcgtac cggctgggcg gacccatctc
     8761 tggcagtaga aaatgccctc gctgctgaag ctgcaggtgt ttctgccctc gccatgcatg
     8821 gccgtacccg tgaacaaatg tatactggcc acgcagacct tgagaccctt tacaaggttg
     8881 cccaagctct aaccaagatt ccattcatcg ccaacggtga tatccgtact gtccaagaag
     8941 ccaagcaacg catcgaagaa gttggtgctg acgcagtcat gattggccga gctgccatgg
     9001 gaaatcctta cctcttcaac caaatcaacc attactttga aacaggagaa atcctacctg
     9061 atttgacctt tgaagacaag atgaagatcg cctacgaaca cttgaaacga ttgattgacc
     9121 tcaaaggaga aaacgtcgca gttcgtgaat tccgcggcct cgctcctcac tatctccgtg
     9181 gaacatctgg cgctgccaaa ctccgtggag ccatttcgca agctagcacc ctggcagaga
     9241 ttgaagccct cttgcaattg gagaaggctt aatagtttaa aacccgtaac tctcttaaag
     9301 agcctcttga atgccgccat tctttcctca tcaaaaaaac tccgtagtct ctagcgctat
     9361 aaatccggct agagattaca gagttatttt ttaatctaaa cttcctacaa gggtatatta
     9421 tctactgaaa ggatatggta tttgtaggga atactttaaa gagttcttac aggaagtcag
     9481 tattaactag ttatattagg tttagtttac ccattcacca ttggtattga ctctatagct
     9541 atctacagtt gtgttgactg caagggcacc tgagccattg acatagtacc atttatctga
     9601 tactttgaac cattggcttg ctttcatagc acctgatgct tcaagatagt accaggtatc
     9661 tccatctttc acccaatctg tcgccatatc accattagcg tttaggtagt accatgagcc
     9721 attgttttgg agccatcctg ttaccatagc accattgctg ttgaggtagt accatgaacc
     9781 attgtattgg agccatcctg tcgccatatc accattagcg ttgaggtagt accatgaacc
     9841 attgtattgg aaccatcctg tcgccatatc accattagcg ttgaggtagt accatgaacc
     9901 attgtattgg agccatcctg tcgccattga accattagcg ttgaggtagt accatgaacc
     9961 attgttttgg agccatcctg ttgccattga accattagcg tttagatagt accatgaacc
    10021 attgttttgg agccatcctg tcgccatagc gccattgctg ttgaggtagt accatgagcc
    10081 attgttttgg agccatcctg tcgccattga accatcagta ttgtagaagt accacatacc
    10141 gttttcttgt ttccagcctg tttttggagt agatggttgt gctggttgct ctggttgtgg
    10201 tgctggagct ggtttttcaa tttttggcgg ttgctgttga gtcaagcgat tatattcttc
    10261 ttctgatcta cgagcatagt cttcttcagc ttgttgatca gctggttttt ctgcttttgg
    10321 ttgttcagct ggcttctctg gttttggagc tggagctgga ttctcaggct cttcagttgg
    10381 tttttctggt tgaggagccg gcgctggttg tggttgttca gctggttttt ctttaacttt
    10441 atcttcttct gctgcttttc gtttagcttc ttcttcttct gcttttttac gatctgtctt
    10501 gattttttct aaccttgtag cctcagcttt tttactctca acttccgctt ttgcttgctt
    10561 aattttttcc ttgtctcgag attccttagc ttcctctttt actagttcaa gctccgcttt
    10621 tttaacttcc acatcggact cagcaatgtc aagttcaagc gttttgtaag taatggttgg
    10681 gtaattacgg cgatcttctt ctttttgatc cttggctttt ttctcagctt cttcaacctt
    10741 cttctcagct tctgctacct tttttcctgg tttcagggat gggcttggaa gagtttcttc
    10801 acctacgcta gaatctgaag acttcgcatc attttctttt ttatcaggtg ttgctggctc
    10861 tccaagagct cctcgttttg tccgcttctt tggtttagct ttaactttag cttcttcttc
    10921 tgctttttta cgatctgtct tgatgttttc taaccttgta gtctcagctt gttcacgatc
    10981 tgtcttgatt ttttttaacc ttgtagcctc agcttgttta ctctcaactt tcgcttttgc
    11041 ttggttaatt gtgtccttgt ttcgagtttt agcttcctct ttcaatagtt caagctccgc
    11101 ttttttaact tccacatcgg actcagcaat ttcaaggtca agcgttttgt aagtaatggt
    11161 tgggtagtta cggcgatctt cttctttttg agccttggct tttttctcag cttctgcaac
    11221 cttcttctca gcttctgcta ccttttctcc tagtttcaat gtatcttttt taaactgctc
    11281 aaaagctgcg tctaactttg cttttacttc tgacggcaac tcagcttccg acttctcttt
    11341 taatccatac aaatactccg ttttaattgc gctcaacttc atgttgaagg cgaaattttg
    11401 ggtatgtttt cttctatcta attgaatctc cctcaacatt ttttctatat attcatcgac
    11461 gacttgttta gcagctttcc tatgttctgt ctttgccata ttagaagaag tggctgcttg
    11521 ggtacttccc tcgttctctg tcgcatgaac cacacttccc ataacaagac tggcaactac
    11581 tacactagct actccaatac taaatttacg aattgaataa tgtacttttc tttcgctttt
    11641 tgatgcaaac atgtttattt ccttctatat tttttcttta accttactat atcacttcaa
    11701 tatgaactgt atataaatcg aattttgtat ttatctcttt atgcttccat ttgggattat
    11761 aacttcatgt aatagctttt cctcttcagc tattcgtcga tacaaaataa ctgcataaac
    11821 tggaaaaact aaaacaaaag tcatataggc atgactcaac aaggtcaagc caatcaactc
    11881 aggtaaaata tttaaaaagt aattaggatg ttttactgtc ctaaacaaga tatgatctac
    11941 atatttgtga ttattgacaa gcataagctt cactgtccaa atatctccca acaagtgaat
    12001 caccaacatc aacatcagca tagaaaaaat aagtaagact aaaccaacca tgctcatacc
    12061 atcaaacatt gtcttatgca ccattgcttc aacgaggcaa gagagataaa aaacaatatg
    12121 aaccaacgtt aatcgttttg tattctcaac tccaaattct ttcccgccat tgctaaggat
    12181 tcgtttctca ttctctatcg aacgctttaa aaaaatcaat cgaataagga atgttactaa
    12241 aataatcgct aataccatat tagtatcctt tcttttatct atatttttat ctatataaag
    12301 aataatacac ttatgttaac cctatatgaa ctttaataaa aaactaatct gtctacaagc
    12361 taatcttaaa ttccataccg tgttcataag ggagaaaact atagtccatt tgatagcttt
    12421 ctaaaatatt attcacaatg taaagaccca aaccggaact ttcatcctta tctgtcacga
    12481 tttgagaatg atagaatata tcaaataaat gttctagttc ttggtcactt agaggcgcac
    12541 atgtattttt gatagagaga tagccatctt gctcggatat gattacgcgc ccatttttat
    12601 ctgaatattt aattgcatta ctaatcaggt ttgtcaaaac cttatccaat gccctaagac
    12661 tcatgacgac cctggtagca tctgtcaatt gattttcaat tgtaacacct attgaatgag
    12721 ctaattcttg ataacgtgat aaaatatcta ctaaaactgg cttaacagtc aaagtctcac
    12781 gacactctgt ccactcttgg aatttagaag actccagtac ttcttccaat aagtggctca
    12841 tctggtcaat cttatttata ctctttgcaa tatattttgg atgatctttg taatctccaa
    12901 tattatgctg catattctct aggataattc taagactggc taaaggggtt ttcaactcat
    12961 gtgatgctcc gcggacaaag gaaacctttt gattttgcaa ttttacaatt tgctcattac
    13021 gactttccaa ttcatgaata accttcaaca agtgctcata cataccatta atctgttttc
    13081 caacttcacc aacttcatct ttcctacttt catcaaaacg aatattgtca tccaaatctt
    13141 gcattttact agtcacttct gaaatgtaaa aaagaggatt gagcaagcgt ttagtataaa
    13201 aataagaaaa aacaaaggaa aaagcaattg taaccaaaaa tgtatatggg agatacaaaa
    13261 gcaaaatatt ctttgcttct ttgtagacat ccaccccgtg aacaaattgt acggttacct
    13321 gtttaccatc tgctgtacta acagacatat ctaacatcac gatataattt gatagctttc
    13381 catctttaat atccaagtca tgcacaagag ggagccgctt atctacaata tctcttttaa
    13441 ggtgagcaga tatggtcaag gactttgaat aagactggag taagcttgga atttcatcag
    13501 atgtcttagt ctttaaatac tccgtaaaca ctcttgcgct ctcattaaac ttttccccct
    13561 ccagttgaat ataataaaaa ggaaaggtca aataaatagc tatatgaatg actagaccaa
    13621 caccacctag aattgcaaaa cttcttaaaa aagacttggt taataattta ggatttttta
    13681 tcataagcta atcttatacc caacattttt cacagtcacg atacaatcta aagctaattt
    13741 tttgcgaaga gtacgaatat agacatcaac gaccctatca caaggtaaat cagctacatc
    13801 ttttgaaatt tcttccaata tctgctctct acttaaaact tgatttttat gctgaatcaa
    13861 acactttagt accagtaatt cctttggttt gagatcaatt tcttcatttt tataatgtgc
    13921 tttgtaagag gtaaaatcca ctgttacatc ctgatatcgc caaagatcct ctatgacgta
    13981 gtaacgtctg ataagcgcct taatacgctt gacaagcagt accaaagaaa aaggttttgt
    14041 cacatgatca tcagcataga gatcaaatac ctgtgactga gtagtttcat ctcccagagc
    14101 actcaagacg atgacaggaa tatcgtgctt ttgattgatt tcttttaaca cttcaaaacc
    14161 actcttccta ggcatcatta aatccagtac catgagatgg atagggagat cttgaaattt
    14221 ttccaagacc tcttgtccat ccttagccat aatgacatga taaccctctt ctgtcagaaa
    14281 tgctgcaatt ccttctctaa tcatttcctc gtcatctgca actaaaatgt tcatctctct
    14341 ccctttctac taccagaact ccatacatct atttcctata tgctatttga aaatttccta
    14401 ccagcctatc atctatgata atggaatgga tttcatttat ccgctacttt ttgtcaacaa
    14461 caacgtcaat acaagaaaat cattcatctt gcagcttata ctcttcgaaa atctcttcaa
    14521 accacgtcag ctctatctac aacctcaaac cagtgttttg agcaacctgc ggctagctgc
    14581 ctagtttgct ctttgatttt cattgagttt cactccactg tgacttatgg tcagatgctg
    14641 atacttttat tcttttatgc aatatcaaat tttaactggc ctgctttgac accaatctta
    14701 agtgtgctgc ctgccactaa atctcccttg agaagaagtt ctgccaactt gtcctccact
    14761 tctgtttgca gggttctgcg aagtgggcga gctcccatct ctgggtcata tccttgattt
    14821 gctaacaatt tcagagctga agcttgtaat ttcaagtcaa tgcctttttc agccaaactt
    14881 gccactaaag gcttgaccat aatcttcacc acttcctgca tatggtcact agataggcta
    14941 tggaagacca ccttctcatc aatacggttg atgaattccg gtctataagc ttttttcagt
    15001 tcttcaaaca tgcgtttttc catattttcc tggtcaaaac gaatatcctt agccccaaaa
    15061 ccaacagtct tatcatcacg aagggcagtc gcacctaggt tcgatgtcat aatgataatg
    15121 gtatttgaaa aatcgacctt gcgtcccttg ctatctgtca agacaccgtc atccagaacc
    15181 tgcaagagaa cattaaagat atctgggtga gccttctcta cctcatcaaa gaggagaacg
    15241 gaatagggtt tattgcgaac cttctctgtc aactccccac cttcttcgta acccacatag
    15301 cctggaggag ctccatttag acggctggct gcgaatttct ccatatactc actcatatca
    15361 aagcggataa gggctgattc gtcatcaaag agaacttctg ccaaagcctt ggccaactcg
    15421 gtcttaccga cacctgtggg tcctaggaac ataaaggaac cgatcggacg cttgtgactg
    15481 cgaattcctg actgattacg gcgaatggca cgactaatgc ttgaaacagc ttgatcttga
    15541 ccgatgacac gtttatggag ttctgcttca agatttaaat acttcttagc atccgtttga
    15601 gtcagttttt gaacggggat tcctgacaag cgactcaagg tggtcaaaat atcagactct
    15661 gtcaccaagt ctttgtagac aggtacttcc tcttcttttg cgattagctg ggctgcctgt
    15721 ttccacttgc catccatcag ggccttgtca gctggactca aatctgaatc gtctgctttt
    15781 acatgctttg ccttattttg cactgttgct gctgcttcgt ccaagaggtc gatagcagag
    15841 tctggcaagt gacgactggt taaataacga tgagccatct taaccgctgt ttcaaccgct
    15901 tcatctgtga tttgtacacg gtgatgtttc tcataagtcg ccttcaaacc ttgtaaaata
    15961 gtcatactat ctgccacact tggttcttca atcgtcactt tagcgaaacg acgagaaagt
    16021 gccgcatctt tttcgatatg tttttgatat tcttcctgag tagtggcacc aaccgttctc
    16081 aaagttccac gcgccaaggc tggtttcaag atattggccg catccagagt cgaatcaatc
    16141 ccgctaccag aacccatgat ggtgtggagt tcatcgataa agaggatgac ttggccatct
    16201 tcttcaatat ccttgatgat attattcatg cgttcttcaa agtcaccacg gaagcgtgtc
    16261 cctgcaacga cattcatcaa atcaagttct aacacgcgca tcttagccat ttccgcagac
    16321 acgtcaccac tagcaatacg ctgagcaaga ccaagcgcca gagctgtttt cccgacacca
    16381 gcatccccaa ccaagacagg gttgttctta gtcttccggc tcaagatttg aatcatacgt
    16441 gagatttcct tgtcccgacc gatgactggt tctaacttgc cagaacgcgc ttgctctgtc
    16501 aaatcatgcg tatagtcctc gagaccacca ctaggagtct gcggcatgcc catcatattg
    16561 gccatagaat tttgcttgtc agctactgta cgatggcgtt ggcgtaaagc cttgagatct
    16621 tcacgagtcc agcctgcccg ttcttctaaa tttcgacgaa gagcagcaat cttgacctga
    16681 tctttcttgt cttcataaga aaaaccagcc ctctccaaga tacgagtcgc caaggcattg
    16741 ccatcatgca aaatcgcata gaggacgtgc tctgtcccta gcaccttagc atggaccact
    16801 gacgctacat actctgcttc gtcaaaaaga acctgcaaac gacgggagaa cggcaattcc
    16861 gtaaaggttt catcctggct atagtccgtt tcagtcagtt ccaaagccac ctcttctaaa
    16921 cggtccatct catacggata atcatttaaa gttgcccctg ctacactata actgtgatta
    16981 gacatggcaa tcaacaagtg ccaagactct agataacgag ctccaaaatg tccagcaacc
    17041 atgtaggcac tttcgataca ttcattcaat gcttttgaat agttcatctt acttcccttt
    17101 tctatctacc tcttgtatga tctgacgtag catgtttgct cgaacaactg gagcttcttc
    17161 tcctaaaacg cgatccaaag ctactgattc tagcaaattc atctcctgct tggtcatcaa
    17221 ttcctgctca accaaaagct ggagaatatc ctcataaatt tcttgactga ctcgctcacc
    17281 aatcgagtaa agcagctccc ggagcatttc atgatgacta gaaaactcaa tccgtcctat
    17341 acgaatgtag cctccgccac cacgcttact ttcaaccaag tagcctctac tttccgtaaa
    17401 gcgtgtcttg atcacgtagt taatctgact aggaacaacc tgaaaggtat ctgccaactg
    17461 actccgttgc aactccacga taccagattg atctaaaatc gccttgatgt aggcctcaat
    17521 atgatccgat gtatttttaa atcttataac aaacccacct ctctctttaa accttgacct
    17581 tgtttgacta ttataccgaa attttctcat ttttaaaaga aaaagggcgc tggtaaagga
    17641 taatcttcac caactcccta tttttctact tatctaagcc taattctgcc aagatttgac
    17701 gtttgtaggc aatcttttgg acttccttgt cctcatcttc agaccaatct agtttaattt
    17761 ctgaaacaat ctgcccaggg cgatttttca agatatagat gcggtcgctg agattgaggg
    17821 cctcctcaat actatgcgtg atgatcaggg ttgttagctg caactgcttg tgaatctcaa
    17881 gataccaagc gtggagttcc atctttgtca tctcatccaa ggcgctaaag gcctcatcta
    17941 agagaaagag cttgtgccca aaaaggtagg tccggagtaa ggctacacgc tggcgcatcc
    18001 caccgctaag ttcatgagga tacttgtctc ttacagctgt cagctggaag gtcgcaagaa
    18061 ttttatccgc tcgggaaata gcttctgcct tatccacctt ttgaatcaag aggggcagaa
    18121 tgatatttcc aagcaccgtc ttgtgctcca agagcagatc cttttgcaac atataactca
    18181 cgcgcccctt gggattttct tcaccatcaa ggacaattct ccctgactga acttctaaaa
    18241 tcccagcgat tagattaaag agggtggtct ttccaacacc acttgggcct aggatggaaa
    18301 ccacttcgcc tgaagtcacc tgtaggttga tatcctctaa aatcctctcc tgaccatagg
    18361 cataactgac gtgctctagt ctaatttctg tcattatttc acaaattcgt tggtgaagcc
    18421 tttgtctgtc aagtcttctt taaggatacc attttcttta tcccatttgt agaaagcatt
    18481 ccagcgagct gcgtcaaatt gaccccattt ttccttgtcg cttgcgtatt cttttgacaa
    18541 gtatttttga gattcgatga caaagtcacg tttttccttg agttcaggtg cattcttgat
    18601 gagaatatct gcagcttctt ctggatgttc catggcatat tggtagcctt ttttgatggc
    18661 ttggatgact ttgcgagctt cttctttgtt atctttcaga tagtcgttgt ttgcgatgat
    18721 aactggtgaa tagtagtcaa actccttgac atagtctttc aagtacatga agttagcatc
    18781 tacaccttga gatttagcaa ggataccatc ccaaccgtag taaatccaag cagtatcaaa
    18841 gacgccattg gcaatcggtg tgattgagtt tgagtcgtta tttggtactt tttcaacctt
    18901 ctcaaagtct ccaccttgag attctaccaa ggttttcaac atagcaagtt cagttgggtc
    18961 attccatgtc ccatatttct taccaaccaa gtcttttgga ctgcttacat tatcagattt
    19021 acgagagatg attcctgatg tattgtgttc aacaatagct gcaacggcag tgattcctgc
    19081 tcctttttcc aatttcttag ccatgtagtc ttggaaatac actgcaaatg gtgcctttcc
    19141 gttgataacc aagtcagaag aactttcttc tggtggcaat ttcaaatcaa catccactcc
    19201 agcttctttg aaataacctt tttccttggc aacataaagc cctgtgtggt tggtatttgg
    19261 tgtccagtct aggataaagt caaccttctt aagttctgcc tctttgttgt ctttagaagc
    19321 agttccttga ccacaggcca caagcacaac agctacaaga gctgttacaa gcgttaaaaa
    19381 cactttccat gttttcttca ttttgatttc ctcttttctt tttcagaaac attctaattc
    19441 tacgaacgtt tccatttaat cacatatttt tcactaatat cgaccaactt catacccaaa
    19501 aggctgataa tcgataccag aataataata gcgaacatgg tatcatactg aaacaatttc
    19561 ttggactgaa tcatataaac accaagcccc tcaaagcctc ccaaccactc agataccact
    19621 gttgtgataa aagcgtagga gacactgacc ctcagaccag cataaaagta gggcaggctg
    19681 actggaattt taaaatgcca caggatttgc caaggcttgg cccgcatcag actaaacaag
    19741 gtcagcatat ccttgtcgca atgcctaaaa ccgtccaaaa tactaacgat gatgggaaag
    19801 gttgtcgtta agataatcaa gacaatcttg ggcaaaatcc cataacctag ccacaagacc
    19861 aggataggag ctatggcaat ggtcggaatg gtctgaatga ccaccatcat agggtaaatc
    19921 aggtcattga gccaagtcaa actatccatg agcacagcca taagacaggc aatcaaaact
    19981 cccaaaatca gccccagtaa agccactctc aaggtcgccc agctatggtg ccagagaaat
    20041 tctctgtcac gaacaaaggg ctggagaatt tcaagaggtg tcggcaggat aaacttgggg
    20101 agaagtttaa gaaaacctgc taactgccag attgacaaga ctccgagaaa gcccaataga
    20161 ctaatgtggc gtctcagtat acttctcaag tttctcatca atacttaaaa tctctcctac
    20221 atttattttg acattggcaa agacattgtc tgcctcctgc cctgccactt ccagcgcttc
    20281 ttttagaatg cgcataagct catcaaactc cccttccaag accgtttcaa atggtgtcac
    20341 taccatcgtc acttcttgag tttgcagata agcaatgacc tgatcaataa cagctatccg
    20401 atcaatcccc tgtgctaggg gtaaaacttg caaggcaatg cttgctttca taagaacctc
    20461 ctcttctcgt tttcctttta aaaaaaaaag aaaaaccttt accatacatg gaaaaggtgc
    20521 aaaattagac taagtatcgt tccctccgct ggcattaccc agatcaggtg cggtcgaagt
    20581 ttaacacttc ctctcagact gtacacagac tcccatatat tatatgtata tatgatagcg
    20641 caaaataaga aaaatgtcaa ggaaactgct tacagaaaag agcaggaaat ttctcctact
    20701 ccaattttct atactcgttc tccatcactg tttactctgt agccatccac cgtcgtatta
    20761 acagctaagg cgcctgaaga gtaagaataa taccacttac cagagacctg gtaccagcct
    20821 gttttcattg cccctgaact acccagataa taccacgagc cattctcctt taaccatcct
    20881 gtctgcattt caccagataa tttcaaataa taccagctag aaccgtcttt cagccatcct
    20941 gttgatttag aaccatttga tttgaaatga taccaactac catttatttt cttccaaccg
    21001 acagttgaac tattattgga tccatagcta gagatatttc ctgattgatt ctgataattt
    21061 tgtgaagaag tcactccctc tagctgtata tagcgacgac ttccgttata agccgtataa
    21121 ctcaaccact tgtagccgtc tttttcaagt atctgatcat aatgaacctt ctctccagga
    21181 taatagtaat caatcacagt tgcactaact aggggttcag ttttgatagc agacttggtc
    21241 ttaaaataat gagttcctcc tgttgaagaa agaacagaat gacctagagg atttttattc
    21301 acagcctcca attgaacata acgatagctt ccattatagg cagtataact caaccactta
    21361 tagccgtctt tttcaagtat ctgatcataa tgaaccttct ctccaggata atagtaatca
    21421 atcacagttg cactaactag gggttcagtt ttaatagcag acttggtctt aaaataatga
    21481 gttccgcctg ttgaagttga ggattgacta ttcccaacac tgccaccatc caaatcttta
    21541 aaatgaataa atcctgtcat cgtgtttgct tttataactc gtttattata ggattctgta
    21601 taaccatagt tatattcctc aatctcaatc tgatctccca ttacatttga cacccaggca
    21661 acatgaccat aagttcctgc agtagaccaa gtaatggaac caatcgtcgg tgtattatct
    21721 acacgataac cttcccgacg agcacgatgt ccccattcat tcgcatttcc ataagctgcc
    21781 ggaatttcaa aaccattgac attactcaaa cgaaaggcta caaaagaagt acactgacga
    21841 gaatacatgc gccactgatc aatctcctgg ctcccatttt tataataagc aggataatca
    21901 tccccacgcg caatcgatcc atttcctctg gaataggcat agacactatc accagctgct
    21961 agcatcaatc ctactactaa aaaaggaaca agctttttaa ctgacatctt caagtaataa
    22021 cttgttcctc ttgctataaa cggtaaaatt ttcattcttc ctccttgaaa aataatataa
    22081 agcgatgatt gccttcacct aaattattcg gagaaaaaag aaaaagtgag aaaatttctc
    22141 actttagtca agataatgaa tcaaattctt ttctgtaaga atatctgagt aagtaaagga
    22201 ttcaacgtaa acattaactt gtttatctcc ttccacatcc ccaaactcca caataaatag
    22261 ggatggataa acttcaatta gcttacccaa tctatttttt tggcgcttac gaccattctc
    22321 caaagtcatt tctacgactt gtccctcatg tgccttgatt tcttctttga tttttttcat
    22381 cttggctaca tctgtaaatg catctgacat cttatgcctc cctctttgag atacttgaaa
    22441 atttattgta ttctttttgg aaaatcaatt ccactgttcc acgagctcca ctacggtttt
    22501 tctcgataat aacttccacc ttattatttg ggataccctc ctcttcttca ccaccacgtt
    22561 catagtagtc atcgcgatag agaaaagcta cgatatcagc gtcctgctca atagacccag
    22621 attcacgaat atcagacaag accggtctct tgtcctgacg ttgttctaca ccacgagaaa
    22681 gctgactcag agcgattact ggaaccttca attccttggc tagtattttc aactgacgag
    22741 aaatttcaga aacttcttgt tgacgatttt ctcgaccagt tcccgtgata agttgcaaat
    22801 agtctatcaa aatcaaacca agatttccag tttcttgagc caatttacga gaacgagaac
    22861 gaatctctgt aatccgaata cctggcgtat catcgatata gatactggcg ttagctagat
    22921 taccctgagc aatagtatat ttttgccact cctcatctgt caattgccct gtacggatag
    22981 aatgtgactc caccaagcct tctgcagcta acatacggtc taccaagctt tccgcaccca
    23041 tttcgagtga aaaaatagca accgttttgt ccaacttagt cccaatattc tgagcgatat
    23101 tcaaggcaaa tgctgtctta ccaactgctg gacgagctgc taagataatc aactcctcct
    23161 catgaagtcc tgttgtcata tgatccaaat cacgataacc tgtcgcaata cctgtaatat
    23221 cggtcgtttg ttgcgagcga gcttccagat ttccaaagtt gagattcaac acatctcgaa
    23281 tgttcttaaa cccgcttcga tttgcatttt cactgacatc aatcaaccct ttttctgcct
    23341 gagcaataat ttcatcagct ggttgtgacg cttcgtaagc ttggttgaca gactctgtca
    23401 acttggcaat taaacgacgt agcattgctt tttctgcaac aatcttagca taatactccg
    23461 cattagcaga agttggcaca gaattaacaa tctcaaccaa gtaagacaag ccaccaatat
    23521 tctgtaaatc accttgatta tcaaggatag tacgaaccgt tgttgcatct atggcatcac
    23581 cacgatcgga taaatcgacc atggcttgga aaatcaaacg atgggcatac ttaaaaaagt
    23641 cccgagactc aatgtattct cgcacaaaaa caagtttact ctcatcaata aagatagccc
    23701 ctaaaacgga ttgctcagct aagatatctt gaggttgtac tcgtaactct tctacttctg
    23761 ccatcagatt tcccttcctt ttacaatctt gtcaagaagg tgtaaactta tccttctttc
    23821 acacgaagat tgattacact tgtgatatct tgatagattt tcactggcac atcaatcaaa
    23881 ccaaccgctc gaatcggagc ttgtacttga atatgacgtt tatcaatctt aattccaaat
    23941 tgcttttgca attcttctgc aatcttctta ttggtaatag aaccaaaggt acgaccatct
    24001 ggaccaactt tttcaacaaa ttctacaaca gtttcttctg cttcaagttg tgctttaatt
    24061 gcttttcctt ctgcaatcat ctcagcgtga gctttttctt ccgatttttg tttaccacga
    24121 agttcaccta cagcttgagc agtcgcttct ttggctagat tctttttgat aagaaaattt
    24181 tgcgcatacc ctgttggtac ttccttaatt tcgccttttt taccttttcc tttaacatct
    24241 gctaaaaaga ttactttcat tcttctttct ccttttcctt tatttcattt aatacaattt
    24301 ctgtcagttt ttcacctgct tctgacaagg ttacatcttt aatttgagct gctgccaaat
    24361 taaagtggcc tccaccgcct aactcttcca taatccgttg tacattcagt ttactacgac
    24421 ttcgagctga gatagagata aatccttgta tattcttcgc aagaacaaaa ctcgcttcaa
    24481 tacctgacat ggctaacatg gcatctgctg ccttactaat aacaactgta tcatagcatt
    24541 tcgtgtcctt agcctctgct attagtacat ctgaacctaa tttacgcccc tgtaaaataa
    24601 gttcattgac ctcacgatat tcttcaaaat ctgtcgcagc gatttcctgg atagcaatac
    24661 tatcacttcc gcgcgttctg agatagctag caacatcaaa tgtccgacta gttactcgcg
    24721 aggtgaaatt tttagtatcc aacatcatac cagccatcaa aacacttgct tgcatacgac
    24781 tcaaacgatt tttcttagaa ttctggaact gaatcaattc cgttaccaac tcactggcac
    24841 tacttgcacc actttcgata taagtaatga ctgcattatc tggaaaatcc tgatcccttc
    24901 tatggtggtc aataacaatg gtttgggtaa ataaatcata aaattctttt gataatgtta
    24961 aggctgtctt tgaatggtct acaagaatca acaaagaacg attggtcacc atccccattg
    25021 catccttaac agacaacaac ttcgtaactc cttctttttc tatgaatgaa acagctcgtt
    25081 caatatctgg agacatttgt tcttcatcat aaagagcata gctattttca atcacattgc
    25141 tggcgaacaa ctgcatacct acagcagagc ccaaagcatc catgtctaaa tttttgtgac
    25201 cgactacaaa aacctgatct acactccgaa tcttatctga aatagctgtc atcatagcgc
    25261 gcgtacgagt ccgtgtacgc ttgattgaag cagcagaccc accaccaaaa taaactggat
    25321 ttttcgtttc gtcgttttcc ttaacaacca cctggtcgcc accacgtact tcagccaagt
    25381 tcaaattgag caaagcaact ttccctatct catcatgatt tccatcgcca taagaaaatc
    25441 ccatacttaa ggtcaagggc aactgtctct gtttcgactc ttctctgaaa gcatcaataa
    25501 cagaaaattt atcattcatc aagccctcaa gcaccgtgta gtcagtaaat agataaaatc
    25561 gatccatact tacccgacga gaaaacatca tgtatttttc tgaaaactct gatataaaat
    25621 tagctacaaa actattgatt tgactaatat ctgactcaga agttgcatcc tccaaatcat
    25681 cataattatc cacagagaca atcccaatca ctggtcgact tgttaccaat tcatctgtta
    25741 tggcttgttc cctggataca tctacaaaat acaaaacacc ggaagaagca tccatatgaa
    25801 cagcataacg cttctcacca agcttggcat aagtagacgg atttcctact gaagccttga
    25861 taatcgtttg aacagcttct aaatcaaaat caccatcttc cttggtcaaa atcaattcag
    25921 catagggatt aaaccactca acctctccag aagataaatt caatttcata acacctacag
    25981 gcatttgttc caatagagat gtcaaacttt cttccgcttg gtggtttaca tactgtatct
    26041 gttctacatc actccttgta taatgcactc tcagtttctt aaataaaaaa acatagcctc
    26101 ctacaaaaag aaacaaaatt aaaaccgtca acagattatt attaacaaaa ataatgaaag
    26161 tggataagac tccaaacgca atcaatccta ctagaatagg aaaaattgga cttacataaa
    26221 attttttcat tcaaaacctc ttggcaccca ttataccata atacccctca aaaagcgact
    26281 ttttaaaggt gtaatcagta attctatcaa ttataagaaa aaggtagttt acaattcagt
    26341 aaacctacct ttacacatat tgaaattaag attctttaac ctctaacaaa ccaatttcgc
    26401 catcctcacg acgataaatc acattggttg tctgatcttc aacatccaca tagataaaga
    26461 aatcatgccc caataaatcc atttgtagaa ttgcttcttc caaatccatt ggttttaaat
    26521 caatttgttt tgaacgaaca actttagact ggacaacatt tgaatcttcc accaaagcat
    26581 ctgtaaataa ttgaccagtt gctaccttat ttttattttt acgctcgatt tttgttttat
    26641 ttttacgaat ctgacgttca attttatcag ttacaaggtc aattgaacca tacatatctt
    26701 gagatacatc ttctgcgcgg agagtaatag atccaagcgg aatcgttact tccactttag
    26761 ccgttttttc acgataaact tttaagttaa ttcgggcatc caactcttgt tctggttgga
    26821 agtacttttc gatcttttcg agtttagaaa ctacataatc acgaattgct tctgttactt
    26881 ctaggttttc accacggata ctatatttaa tcatatgaat accttctttc taaacatttt
    26941 tgtttttatg attttattat aacgctttca ttctattttt gcaaattttt tcctcatctt
    27001 acaagggaaa atgtttttac atccttagca ccggcttctt ccaacagttt cttaacacga
    27061 tttatagttg ctcctgtagt atagatatca tctataagta ggattttttt aggaatagtg
    27121 actccacttt taataaagaa aggaagttct gtccccaagc gctctgaacg atttttagaa
    27181 gaactggctc tctcttctct tttctctaat aaatctagat actcaaagcc tgctgcctct
    27241 accaagccct caacctgatt aaatcctctg ttagcatatc tatcaggact taggggaatt
    27301 acaacaaatt gatactcttt gtactttttc aactcctcac ttaaaaatga agcgaaaact
    27361 tttcttaaca ggaagtctcc atcaaactta taccgactga aaaaatcctt catagcttga
    27421 ttgtaagtaa aaatcgctct atgactgact tcaactcctt ctttacacca aagttgacaa
    27481 tcttgacact ttgttgacaa ctctgttttc atacaatttg gacagttctc ttccccaatt
    27541 ctttcaaaag tagaatcaca gtctgaacaa agacaagagt catcattcct cagaagtaag
    27601 agactactaa aagttaaaac agtcttcata gtctgcccac ataacaagca cttcatagac
    27661 cagcctcctt attcatcatc tgaatttcct taatcgcctt cttgattgaa gcatttaacc
    27721 catcatggaa gaaaagcaaa tctcctgtcg gtctatccat gcttcgtcca actcgtccac
    27781 caatctgaat caaactagac ttggtaaaca aacgatgatt ggcctctatt acgaaaacat
    27841 ccacacaagg gaaggtaact ccacgctcca agattgtcgt actgataagt attgtcagtt
    27901 ctccatctcg aaaagcttgt acttgctcta atcgatcctc tgttacagaa gatacaaagc
    27961 caattttctc atttggaaat tgctcctgta agatttcttc taactgctcc cctttcttaa
    28021 tttccgaagc aaaaatgagt aacggataag ctgtctttct ctgcttctca atataggact
    28081 ttaactttgg tgacaaacga ttcttgtcta agtagcgatt aaaatccgat aaccaaattg
    28141 gttttggaat aatcaacgga tttccatgaa accgtctcgg taaactcagt ctttttagtt
    28201 ctcctaaacg gaccttttta tctaactcat tggtcgaagt cgctgttaaa aagattctca
    28261 atccattctc ctttacacta ttcttgacag cgtggtaaag cgtgggatta tcaacataag
    28321 gaaaagcatc tacttcatcc actatcagca aatcaaaagc ttgataaaac ttcaataact
    28381 gatgggttgt tgcaacaact agtggtgttc gaaaataagg ttccgattct ccatgtagca
    28441 aagctatacc gcaagaaaaa tcctgttgca ggcgcttgta cagctccaaa caaacatcta
    28501 tgcgaggact agccaaacac actgcaccac ccgcattgat cactttagcc actacttgat
    28561 aaatcatttc tgtctttcca gctcctgtta ccgcatgaac taaggttggc ttctgcttgt
    28621 ctactgcttg aagcagtccc tctgacacct tctcttgaaa aggagttaat tggccgcgcc
    28681 atttgagaac atcttgcttc ggaaaatcct cctgcggaaa atagtataaa gtttgatcac
    28741 ttctgactcg cttcatcagc aagcactctc gacaatagta agcaccgatg ggcaaatacc
    28801 attcttctag aatagtacta ttacagcgtt gacagaaaag tttccccttc tcctttctca
    28861 ttgctggaag tttctccgcc aactgacgtt cttcttctgt taattcattc tcagtaaata
    28921 aacgaccgag ataatctaaa tttactttca tacttcttta ttcgtaaaaa ctagcacttt
    28981 agattatttt ttagtacaat taaatcatgg aatttaggac aattaaagag gacggccaag
    29041 tccaagaaga aatcaaaaaa tctcgcttta tctgccatgc caagcgtgtt tatagcgaag
    29101 aagaggctcg tgacttcatt actgccatca aaaaagaaca ctacaaagcg acacataact
    29161 gctctgcctt tattattgga gaacgtagtg aaattaaacg tacaagtgat gatggtgagc
    29221 ctagtggtac tgctggtgtt cccatgcttg gggtactaga aaatcacaat ctcaccaatg
    29281 tctgtgtggt cgtgacacgc tactttggtg gtattaaact aggcgctgga ggactaattc
    29341 gtgcttacgc cggcagtgtc gccttagctg tcaaagaaat tggtattatt gaaataaaag
    29401 aacaggctgg cattgctatt caaatgtctt atgctcagta ccaagagtac agtaacttcc
    29461 ttaaagaaca tgatctcatg gagctggata caaactttac agatcaagtc gatacgatga
    29521 tttatgttga taaggaagaa aaagaaacta ttaaagctgc acttgtggag ttttttaatg
    29581 gaaaagtcac tttaactgac caaggtttac gagaggttga agttcctgta aacttagtgt
    29641 aaacaatgaa taatacagcg tttcgttgac attctcacaa ctactttagc gagcaaaata
    29701 aaaagatgcg taccaaaata tactagaaaa tgaagcaatt caaacgaaac ctgatatcgt
    29761 tttccttcac acctatttac tagaattagc tgaacgcaat cacttgaaaa ttaatgactt
    29821 tgatctatga tatatagaaa tcctatcgct tcgataggat ttctatattt tacaaatggt
    29881 atagatagcg ttatactaaa gatatcttat acaaagaggt attcatatgt ctatttataa
    29941 caacattact gaattaatcg gtcaaacacc gattgttaaa cttaacaaca tcgtgccaga
    30001 aggtgctgca gacgtctata taaagcttga agcatttaat cctggttcat ctgtaaaaga
    30061 ccgtattgcc cttagcatga ttgaaaaagc tgaacaagat ggtattctga aacctggttc
    30121 tactattgtt gaagcaacaa gtggaaacac tggtattgga ctttcatggg taggtgctgc
    30181 taaagggtat aaagtcgtca tcgttatgcc tgaaactatg agtgtagaac gacgtaaaat
    30241 tatccaagct tatggtgctg aactcgtcct aactcctggt agcgagggaa tgaaaggtgc
    30301 tattgctaag gctcaagaaa tcgctgctga acgtgatggt ttccttcctc ttcaatttga
    30361 caatccagct aatccagaag tacacgaaag aacaacagga gctgagatac tagctgcttt
    30421 cggtaaagat ggattagatg cctttgttgc tggagtaggt accggtggaa cgatttctgg
    30481 tgtttctcat gcactcaaat cagaaaattc taacattcaa gtttatgcag tggaagctga
    30541 tgaatctgct attctatctg gtgaaaaacc tggtcctcac aaaattcaag gtatctcagc
    30601 tggatttatt cctgatacac ttgatactaa agcctatgat agtatcgttc gtgtaacatc
    30661 agatgatgct cttgcactcg gacgtgaaat tggtggaaaa gaaggcttcc ttgtagggat
    30721 ttcctcagct gcagctatct acggagccat cgaggttgcc aaaaaattag gtacaggtaa
    30781 aaaagtcctt gctctagcac cagataacgg tgaacgttat ctctctacag cactctatga
    30841 atttgaagtt tagtctccta aatacaattg gcccttatta tagggctttt tatttttacc
    30901 ttgaaaatag gaagctctcc ctataaggat cgactgcata caaaaaagga agcaatttgc
    30961 ttcctttcta ttattagtta ttcaaggctg ctgccattgt agctgcaact tcagcttcga
    31021 agtcgtttgc agctttctcg ataccttcac caacttcaaa gcgagcaaac tcaactaccg
    31081 aagcgttaac tgattcaagg tatgcttcaa ctgtcttgct gtcatccatg atgtaaactt
    31141 gtgcaagaag tgtgtaagct tggtcaactt tagtgttatc aagcatgaag cgatccattt
    31201 tacctggaat aattttgtcc cagatttttt ctggtttgcc ttctgcagcc aattcagctt
    31261 tgatgtcagc ttcagcttga gcaataacat catcagttaa ttgagctttt gatccatact
    31321 tcaagtgtgg aagagctggt ttattaacca ttgcacggct ttcgttgtct tggtcgataa
    31381 cgtgattcaa ttgtgccaac tcatctttaa cgaattgctc atccaattct ttgtaagaaa
    31441 gaactgttgg tttcatcgct gcgatgtgca ttgacaattg tttagcaagt gcttcgtctc
    31501 caccttcaac aactgaaata acaccgatac gtccaccgtt atgttggtat gctccaaagt
    31561 gttgtgcgtc tgttttttca atcaatgcaa agcgacggaa tgagattttc tctccgatag
    31621 ttgctgttgc agatacgtat gcagcttcaa gagtttcacc tgaaggcatt atcaaagcaa
    31681 gagcttcttc attgttagca ggttttcctt cagcaatgac tttagctgta gtatttacca
    31741 attcaacgaa ttgagcgttt tttgcaacga agtcagtttc agcgtttact tcaataactg
    31801 ctgcaacatt accgttaaca taaacaccag tcaaaccttc tgcagcaaca cggtcagctt
    31861 tcttagctgc cttagccata cctttttcac gaagcaattc aatcgctttt tcgatgtcac
    31921 cgtctgtttc tacaagcgct tttttagcgt ccataacacc ggcaccagat ttttcacgca
    31981 actcttttac aagtttagct gtaatttctg ccattttaat tctcctatat tttttgaaaa
    32041 taggagagcc gggctaagcc ccgccctcct aggtaattac tatttgtata aattaagcgt
    32101 tgtcaccttc tacaacttca acgatttctt caattgaatc tgcttgagtt tctgaagctg
    32161 caaattctgc ttcaactgct actgcatcct caccttgacg tccttcgata atagcgtcag
    32221 ccaatttagc tgtgatcaat ttaacagcac ggatagcgtc atcgttagct gggatgatta
    32281 catcgatatc atctggatca gtattggtgt caaccatcgc tacaactggg attcccaatt
    32341 ttttagcttc tttaacagcg atttgctctt tatgtgggtc aactacgtac atcacatctg
    32401 ggatacgagg catatcttcg ataccaccca agaatttttc aagacgcgca cgttgtttgt
    32461 taagaagtgc aacttctttc ttaggaagaa cttcgaaagt tccatcttct tccatacgtt
    32521 taatttcttt caaacgagcg atacgttttt ggattgttcc ccagtttgta agagttccac
    32581 ccaaccaacg gtggttgatg aagtattgac ctgaacgtac tgcttcttca gcaactgcat
    32641 cagctgcttg tttcttagta ccaacgaaca atacaactgc atcgttagct gctgcatcac
    32701 gcatgaagtc gtatgcttgg tcagcgtatt ttacagtttg ttgcaagtcg ataacgtgga
    32761 ttccgttacg ttcagtaaag atgtacttag ccatcttagg attccagcga cgggtttggt
    32821 gaccaaagtg tacaccagcc tcaagaagtt gtttcattga aattactgcc atgagtattt
    32881 ctcctttttg tttttttcct cttcttgact tcaactcgca aaacgaccca agggcaactg
    32941 cttcacaatt catcaagaat gagtattatc gttcacacga caattttcat tttaccatac
    33001 ttttccaata ttttcaagct attttgatat aatttttaat agggattgtc acggtaaaac
    33061 ctgaaaagag ggctctattc gagtccctct gtaaattaat ctgcataaat atatgtaaca
    33121 aaaccttcag aagttgttgt tggattgaac catccacggt gatttccaat tgtacgatta
    33181 cctgcataat ttgattctga tacttggata cgtgttgttg attcaacagc tgtaacaacc
    33241 gctacgtgac catatccacc atcattccaa catgcaattg ctccaacttg aggtgttgaa
    33301 cctgtacgga aacctgctgc tgctgcactt gtagcccact gtgctccatt accccagtag
    33361 tctccagccc aaggtgccaa tgtttttact ccccatgtac attctccaat tggataactt
    33421 gaagcgtttg tactgtatgt tggacgaact tttgcacgga caggtgctgc tgcagattca
    33481 gatactgctt gcacttgagc tgttaagtta gtgtttgctg aagcaagtac tgattgttgt
    33541 tggctagctc gtttttcttt ataagctgct tctgccaccg cagctgcacg agcctctgcc
    33601 tcagctgctg ctttttgctc taatagactt gctttttccc cttcagctgt cgctttctca
    33661 gcagcaagac ttaattcagc agcttttagt tctgcctgtt tcgtagtcaa tgcttgagca
    33721 tcatcagcca atttttgttg attagcaatt acaatattga tagcatcatt atttgctact
    33781 tgtttttcag aaatagcttt tttatctgcc ttttgttgtt ctaacatttt gttgtttgca
    33841 gatacgattt cactcattgc agcaacacgt gaaatagctt ctgtaattga ttttgagttt
    33901 acaatggtat tgatatagct agttacggct ccatttgttt gagcactacg agcttgtttt
    33961 tccaacgatt ggttacgaga aacaatgttt ttagaaagtt ctgtaatctc accctcgagt
    34021 ttcttagatt ctgcttgtaa tctatcattt tcagcttgca agttagactg ctcagcttga
    34081 atagctgata cttgctcctg aatttggtca acttgttttt gggcttcttg ttgttgtgct
    34141 gttaagttac taattttatt atcttgagca gcaattttgt catcagtcgt ttctgcatgc
    34201 gcagttgtta aaacagctac ttgagaaacc attactgtac ttaataaaag tgacgctaag
    34261 atttttttct tcatattacg tagatactcc ttcttttaaa gacaatacta gtataccaaa
    34321 aaaaggccta ataaatatta cgcctttgtt acatttatat gtcgttctta tagataatat
    34381 ttttcaaaaa taaattgaaa aacagtaatc cataaaaaat ttaaaatcat cgtcggtacc
    34441 aagctataga ctataaaaat cgacatgcta tctactgtca accctaccat aaaagccaaa
    34501 agataactac ccatttcaaa caggaatgtc agcacaatca tagctagcat tcttgtccaa
    34561 cgattcaaca aaataacact attcaattta tgaaggaagg ctcccaataa gataaataag
    34621 agagttgtaa tccctattag atggaaaaag taaacatcat aaaccaagcc tataacaaaa
    34681 caatagacta ggtagagata ctctgatact tctatcgtct caaataagag aaatagaaaa
    34741 agaaaatgac tagccaaatg tacatggggg aaaaatgagc ccagaagctg gctaatatgg
    34801 gcgtcaatta gaacaaagaa aggaagcaat aaaaatactc caactcgctt caactgtctc
    34861 attatgaatt ccccactaat tctatcacat ctacattatg agtatctgca ctcaatttaa
    34921 cagttacttc tcgtgtcaaa tagtctgtac tatgcgttgt ggcaaccact tcaccaacag
    34981 gaatatcagc aacgttaaag tttcctaatc caccagtagt caccttatct cccgcactaa
    35041 tatcgctatt actatttaat tggctaattt taagaacgtc attttccttg tcatagccaa
    35101 taataattcc ataaattgta gtagagccat gttgaatttt aacagaaatc ttatcagcat
    35161 tttccgtatt tgtcagaagg ttgactatag tagagttctc ctctactttt gaaacactcc
    35221 caatcaagcc accatttgca atagctaaca tgttctcaga agcacctttt gatctacctg
    35281 catctaaggt caactcctgc ttccaagata ccggagaacg cataataaca tctgctgcta
    35341 aagtctttgt ggcttgcaat ttagacttca tatcaagcaa ttggcgcagt tgttcatttt
    35401 ctgtctttaa actttccacc tcatttgatt taacttctaa ttggtaaagc tgtttcttca
    35461 aactttcatt ttcattatat gttcgtgtca aatgagccaa atctgatttg acagaatcaa
    35521 accactgaaa aggtttttgt acaactctat caaccaatga gattccatct cctaattttg
    35581 tcacaattgt acttgaataa gtcgtcgcta agagagctga cacaagcaga acagtgacaa
    35641 aaacaataat gacatatttt gattttttaa aacggttcat attcctacct ttatatcaaa
    35701 aactgttaca gtaacttttt atcaattcct gaaagctact aagattttaa gaaaaataaa
    35761 caacaaccaa gtacgagaat aacaagaatg gtcagcgtat cctttagagt ccatttcaat
    35821 tgtcggtatt gacttctgcc ttttccaccc tgatagccac gcgcttccat agcgatagcc
    35881 aaggaatctg cacgttttaa acttgtcgca aaaagaggaa tcaaaatggg aatcatcgcc
    35941 tttacttttt gaacgatgct tccttctcca aaatccactc cacgagcttt ctgtgcattc
    36001 ataatccgcg tcgtatcatc catcaaggtt gggacaaaac gcaaactcat agacagcatc
    36061 aatccaattt catgaactgg aactttcaca cgctttaaag gtgctaataa agcttcgaca
    36121 gctgatgcca aacttaaagg catggttgtt aaggttaaca aagttgaaaa gaaaataatc
    36181 aatacaaagc gacaaaaaat aatcccagct tgttgcaaag cataatccgt gattctcaca
    36241 aacgaaaact caaataaaac attcccatta gaaatgaaaa atagttgaaa aatagttgtg
    36301 aaggcaatca agaaaaacat agacttcaag ccctgaataa aaaatgaaag agatactcct
    36361 gacaaggcaa taaatatccc tgtcgctata aaaagaatca gattcgtcaa ggggttatta
    36421 gcccaaaaca caatcaaaat cagtagcatc atagcaagca atttgctacg tggatccaat
    36481 cggtgaacaa tcgaatcccc tgggatataa cgccctaaaa tcatactatc catttagcga
    36541 ctccttgaac tcctctatct taatcggtaa tcgtttaaat gacacgcctc tatcagccaa
    36601 tcgtttacaa aaggccgtaa ttttaggtac tcccaactga acttcttcca taaaaacaac
    36661 gtcttgaaag acatcacttg gtttgccccc ctttactaaa cgtccctttt ccattacata
    36721 gacttgattc gcatattcag caacatcatc catcaaatgc gttaccaaga cgatggtcat
    36781 ccctgactgg tggagttttt tgaacagggt catcaactct tttctcccta gaggatctag
    36841 accagctgtt ggctcatcta agactaatat agctggctcc atggcaagta tgcctgcaat
    36901 ggcaacacgt ctcatttgtc cccctgacag ctcaaacgga ctacgatcaa aaagtgattc
    36961 atcaattcca accagagcca gtttctcacg cgcagtcttc acagcatctt cttcagaaac
    37021 tccaaaattt tgcggtccaa aagcaacgtc cttcaaaacc gtttcttcaa aaatctgatt
    37081 ttcagcaaac tgaaatacca agccaacctg ttttctaatt tgacgaatat ctttattttt
    37141 agaagtcgag gtgattaagg tatcaaaaac cctcacactc ccttgatttg gcaccaataa
    37201 accatttaag agttgtaaaa tagttgattt accactacct gtgtgcccaa ttaaagctgt
    37261 ataagagcca tcttcaatcg tcaaagaaac atccgacaaa gctgctgaag ctaagggagt
    37321 accttcttga tatgtaaaat tcacattttc tagagcaatt cccatagctt atcctctagc
    37381 tcactttctg tcaaataatt ttcaggtaaa tcatagccat tctggctcaa agattttttt
    37441 aattgattag caaaaggatc gtctaatcca atttgatcta aatcatttcg agagaaaagc
    37501 tcccttggac tactagttga ttcaatttcc ccttttttca tgaccaatac gcgatcactc
    37561 atggcgactt cttccaaatc atgggtaata gaaatgaccg tcatatcata gtcttttcga
    37621 attcctttta ctgtcccaat aagttctcta cgcccctcag gatccaacat actcgttgct
    37681 tcatctaaga ttaaaatagc tggtcttagg gctacaacac ctgcaatggc cacacgttgc
    37741 ttttgaccac ctgatagacg cgctggctct ctctttttaa agtccaacat gccaactaaa
    37801 gccagagctt cttccactct ctttttcatt tcttgacgag aaagtccctg attttccaaa
    37861 ccaaaagcaa catcatcttc aacagtcgct ccaacaaatt gattgtctgg attttgaaaa
    37921 accataccga tttgacgacg tatattccaa acattttcct cagtcaaacg ttggccatca
    37981 attacaatct ctccggattc tgcttccagt aagccatcaa ttaatcgaac cgtcgttgat
    38041 ttaccactac cattatgccc tacaatcgaa agccattctc cacgtttcac gtgaaacgta
    38101 atatccttca catcgtagta gttctgattt tctttatagc gaaaagaaag attttttaca
    38161 tcaattattg atttcatttc gaaccaaatg tccctttaaa tacataggca ctacccttaa
    38221 aatagtcata gccagagtag atagtgaaaa ataaggctac ataaagtaga acttgaccaa
    38281 gcaaagtcca atgtaatagc aagaaaataa tagcaaacat ctgactaaaa gttttaattt
    38341 ttccaggcat tgctgctgct aaaattgttc caccagtttc aaccaataaa agccttaaac
    38401 ctgtcacagc taactcacga catataatca ctgcaacaat ccaagccgga gccataccta
    38461 actcaatcaa cataataaaa gccgacataa ctagtaactt atccgccata ggatctgcaa
    38521 atttaccaaa attactgacc acattccatt tacgagctaa atatccatct aaatagtcgg
    38581 taatactggc aacagcaaag ataatagctg caactatatg actctctatc gaatttccta
    38641 tcgttaaaat aaagataaaa ataggtataa agagaattcg acctattgtt aagagattgg
    38701 gaatttgttc ttttttcatt cgtttttcct taatttttag taaaggttac agtgatttgt
    38761 ccagtctgag ctgttaattt cgataaatca acagtctgat tatctactgt caaatcaaca
    38821 ccttttacaa cacctaacgt aattgttaca ggacttttag ttgcaactgt tgcttctgca
    38881 cttttcttct ttggcgataa ggttacaccg ccctcaagtt cgctttctga aacactgacc
    38941 caacttgtaa catctgaaac tgccaattgc aatttaactg tttccttact tgtcttataa
    39001 gcgatttcta catgatttcc ttcgcctgat acacttatag ctgattctat actagaagaa
    39061 ctactacttg aggagtgggg aacagagcta gttgaacttg ttgattgaac cacactgtaa
    39121 ttagaaagag aaggctcctc tggttgagtt tgaatatagt tccaaacata ataagtcaca
    39181 aaaattaaaa tcgataaagc aaaaaggata aaataaaata aaggtaaaaa tgatgttttt
    39241 ttcttctttt tcttacttga acgtctacga cctgtcaact catcttcatc aacatctact
    39301 tcctcataag taatcatact cccagaatca taagcatcca aaacaatttg gtcatctaac
    39361 tcaacagccc atgcatattt tttcaagaaa gaacgcgtgt aaaaaggact tggaagttga
    39421 tcgaaatcgt ctgcttccat tgcttccaac atatctaact ggatttctgt ctttttctgc
    39481 aattcatcta aactcaatcc ctgattgatt ctagctaatc gtaaaacctc tccaattgtt
    39541 ttttttctca tacttgtcat cccttctttc tagtgtctat tatgataggt tactacgatg
    39601 gaaatattgt aaaatcaact atgtcaccat catctattaa atgatgtcca gcatcaagga
    39661 catcctctaa agtaatttcc tgtaaaattt tcggcaaatc aaaaattgtc tcaccatttt
    39721 caaaagcatc atattgcgtt gcaataaatt caagagagtt catgctactg aaaaattcgc
    39781 caaacatctc tcttttgata atatctaaat gttcctctgt aatatctaaa tcctttgtaa
    39841 aattacgaat agccttccta aattgatgag acaaagcaac tggctctttc gtatccattg
    39901 tcaacatgac aaaatgaaag cgacttgtta tttcaacttc cagagataag gacgcatcaa
    39961 ttttacctga ttcataacat ttttgaaaac gatccgaagt ccaaccaaac atcattgcaa
    40021 acaataattt taataaaata tgatgtcgat agcaatccgc ttcagaaact tctcgcttac
    40081 ctctaactcc aatcgctagt ttgggagaag atacttccat tctcatacta tctgttagct
    40141 ttacaggctg taaaaacaac ttttctcttg ctacttcctg aaaatctgaa tctttcagtt
    40201 ctttgctttc aaaatagtcc tgtactcgct ccacatcaaa attaccaact aaaaacagag
    40261 acatgtttac aggtttgtaa aactttgtaa aattttcttg caaattagtt agattgattt
    40321 gggaaatgga ctcctcactt ccaactatat cagttgctaa aggtgtacca ggatacaaat
    40381 tcgctaaagt tgaaaagaat aaacacgaat ctggatcatc ttggtacatt tctcgttctt
    40441 gctgaataat atcctgctct gtcagaatgg aagcttcagt aaagtgtgct gatgttacca
    40501 attcatcaag taaatctaaa ttttctaaaa aataatccgt tgctgaaaaa agatagtttg
    40561 tttttgtaaa gcttgtaaag gcattactat ctgcacctat actcgtaaaa gccgacatca
    40621 aatcactaga atcttctctc tcaaataatt tatgttcaag aaaatgagca attcctccag
    40681 gatattgttt tacatctccg tcaacttctg tgacaaacgt atctaccgaa ccaaactgta
    40741 cagtgacact cccgtaaacc tctttaaatt cctttttagg caaaagagca actgtcaatc
    40801 cgttggccaa acgagttcga taaacctttt cttttacagc tggatagtat ttttcttcaa
    40861 aaacaacctt tgtcattcta ttccttccat aaagtaaatc gcttgtagtt tcacattatt
    40921 agctactcta caaatagcat ctttgtcaat ttgttcaagc tttgcaatcc aacttttaaa
    40981 gtctgctgaa gattttccaa ataaggcatt ttgataagca cgttcaatca atgaagattg
    41041 attatcttga gaaagtaaca acgaccaacg aatcatttcc ttggtctgat ttaactcaaa
    41101 ctctgtaaaa taaccttttt ttaaatcaag cagttgatta ttcatcattt tacgagcctg
    41161 gttacgattt tctcgattga taccagcata catcctcaag aatccactaa ataaatcaag
    41221 ctcacttgaa atggtataag ctaatccagc attttcacgg acatttgtaa agagcttaga
    41281 gtgagcaaat ccaccaagta aaccattcat tacaatcatg ggtaaatgtt gttcatcacc
    41341 atatttagaa cggtaatgat aacctaattc caaaatggat tgtcccacat ttttccgaac
    41401 cataccttcc tgaaggatat tagaataagg ttgacaatac tgaaccttca catctccttt
    41461 tcgaccttta aagccaaatg attctaatac attttgaatt tcaacctcat taaaatcacc
    41521 taggaaaaag aaatctattc gatcattggc taaaaattct tggaaacaag aataagaact
    41581 ttgtggagtt tcagctaaaa tacgatttcg taaatcacta tattccaatt gaagacgttc
    41641 atcatgaaaa aacaatttat ccaattcttt atgtgcaaaa taaaaagaat catccatatc
    41701 agctgctaaa cttgctagca attgtttttt ctcaatttca aataaggccg gatcaaaccc
    41761 attatcaact actacgggtg aaaaaagagt ttcttttaca agttccaaaa tctgagaggt
    41821 tagcacgttt ttcctactta aaaactcatc acgaacatag gtaaatgtca attctataat
    41881 gtggctttgc cctcttctga aacaattggt tgacatatct gtaccgtata gactggccaa
    41941 gtgtctcctc aaatcttgag aagtggggta catctgatta gcagtctcta gcatacttgc
    42001 actcaacatg tgacctgcaa tcgtatcaag ggataatgga gcggtaaaac gcacggtaat
    42061 tttgtttgtt ttaaactttt ttgattggat aaaatgtgtt gaaattccat gcactaactc
    42121 catgatttac ctccttatat acagacttct attatatcac gaaaacctga aattttcttg
    42181 ttccctgtaa cacttttgaa ataaaaatcg cttacatttc tcgctgtctc tctcactatt
    42241 tttaggaaaa tatggtataa taccaaagat tgaggtgaat tatggaatac aaattatttg
    42301 aagaatttat taccctccaa gcactactca aagaacttgg aattacacat agcggaggag
    42361 ctattaaatc atttctctct gaacattctg tttactttaa tagggaatta gagagtcgtc
    42421 gtggaaaaaa acttcgtatt ggcgataaag ttgacatccc tgacatgaac attgacatct
    42481 tgttgacaca acctacttct gaagaacaag atgaatacca agctgataaa gttgaaaaag
    42541 aacggatcgc taaacttgtc aaaaagatga ataagggagt taaaaaagac aaatcgaaac
    42601 ctgcttcatc acctaaaagc caacaagctc cacgattccc tggtagataa tcatgtggct
    42661 acaacatcta tctctcaaga cttttcgtaa ttacaaagaa acgaaaatag actttaatcc
    42721 taaattgaat gtctttttgg gacgtaatgc acaaggaaaa acaaacatgt tagaggctat
    42781 ctatttttta gccttaacgc gtagtcatcg aactcgaaca gataaaaatc tcattcattt
    42841 tgatgaggaa caacttcatc tttcaggtct cgttcagaaa aaaactggat ccattcccct
    42901 agaaatcgaa ctaacacaaa aaggccgtgt aacaaaagtt aatcacttaa aacaggcacg
    42961 cctttcagat tatgtaggac acatgaatgt tgtcttattt gctcctgaag atttacaact
    43021 aattaaagga gcaccttcga ttcgacgaaa attcattgat atggaacttg ggcaaattaa
    43081 gccaatctat ttatctgact taaccaatta taaccacatc ctaaagcaaa gaaacactta
    43141 cctaaaatca gctcaaaaaa tagatgaaac attcctttct gtgttagatg atcagctagt
    43201 tgattatgga tgtcgtgtaa tgaatcaccg cttagatttc ataaaaaaac tagaatcatt
    43261 tgggcgtaag aaacattttg aactctctaa tcagatcgaa gagttgtcaa tatcctatca
    43321 atcttctgtc aatataactg acaaacaaaa cttatccgaa tctttcaaaa ttgctttaga
    43381 aaaaagtaga tccagagatt tatttaaaaa gaatactggt gtcggtcctc atcgagatga
    43441 catttctttt tatataaatg ggatggatgc tagtttcgga agccaaggtc aacatcgtag
    43501 tctcgtcctc tcgataaaat tagcagaaat cgaattaatg gaaagcatta ccacagaatc
    43561 tccgatatta ctgcttgacg atgtgatgag tgaacttgac aacactagac agttaaaatt
    43621 attagaaacg atttctcaat caatccaaac ctttatcaca acaacaagct tagaccatct
    43681 tcaaaatctg ccagaaaatc taagtatctt cactattcag gatggtaaag ctgctgtaaa
    43741 tggaaattga caacattgta aaagaactcc tgttttcact ggggttcttt tcattgtttt
    43801 ttacatagaa taatttggtg cctcattagt aatttgcaca tcatgaggat ggctttcttt
    43861 caaaccagca ccagacattt caataaattg agcattatcg tgtagttctt taaggttagc
    43921 tgcaccacag taacccatac cagagcgaat accaccaatc atttggaaaa caatatcagc
    43981 tgccgctcct ttataagcaa cacgaccttc aattccttct ggaacgagct tgtttgcttc
    44041 attgacagaa ccttggaaat aacggtcgct tgaacctttc ttcatagcag caattgatcc
    44101 cataccacgg taagtcttga atttacgtcc ttggaagatt tcagtttcgc ctggagcttc
    44161 atcagttcca gcaaacatag atccaagcat aacagcattt ccacctgcag caagtgcttt
    44221 tacaatatct ccagaatact tgatcccacc gtcagcaata atcgttttac catattcgcg
    44281 cgcaacagct gcagcatcgt agatagctgt tacttgcgga acaccaacac cagcaatcac
    44341 acgagtagta cagatagaac ctggtccaat accaacctta acaacgtcta cacccgcttc
    44401 ataaagggca cgtgcacctt cagcagtagc aatatttcca gcaatcaaag tccgatctgg
    44461 gaaatgagca cgaatctcgg caattttacg caagacacct gcagaatgac catgtgcagt
    44521 atcaataaca atcgcatccg ctcctgcctc aaaaagagcc tctgcacgtt caaatgtatc
    44581 tgaagtaaca cctactgcac ctgcaactag aagacgacca aactcatctt tagccgcatt
    44641 tggaaactca ataacttttt caatatcttt gatagtgatc aaaccagaaa gactgccttc
    44701 ttcatcgacc aacggaagtt tttcaatacg atgctcttga agaatactct cagccgttgc
    44761 aagatccgta cccacaggag cagtaacaag attttcacta gtcatatggt ttgaaattgg
    44821 ttgattataa tctgaaataa aacgaagatc tcggtttgtc aaaataccaa ccaatttacg
    44881 attttcaagt gtttcaacaa ctggaacacc actgatgcgg taacgaccca taagctcatc
    44941 tgcttcagca attgtatgtt caggcgtcaa gaagaacgga tcaataataa ctccattttc
    45001 agaacgtttt accttacgaa cctcgtctgc ttgttgagca attgacatgt ttttatggat
    45061 aactccgaga ccacctgcac gagcaatagc aatggccatt tgactctctg taactgtgtc
    45121 catggcagcg gtaataattg ggatatttaa agtcaaatta tctgccaatt tagttgttaa
    45181 atctgcatcg ttaggcaaca catgactttc agctggaata agcaatacat catcaaaggt
    45241 aaaacctttt ttcaaaaatt tagtgtccca attagacatt cgaagtttcc tcttttcttt
    45301 ctttttgagc ttgactcttt ttatattgta tctatcatac cattctataa aaatttgtca
    45361 aatgttacag gggtaaataa aaaactatct tttcttcgag atagaaatga tagtttcttg
    45421 taaaataaac ttagttaaag taatgaagtc ccattgcccc ttttacctca gatagggttt
    45481 gacccgcaac ttcacgcgct ctttcactac ctttttgaat catattataa acttctccca
    45541 tatccttagc aaattcaata cggcgctcac gaataggacc cagttcacgt tctaatattt
    45601 caagtagata acgcttggtc ttcacatcac caagaccacc tcgttgataa cgttctttca
    45661 tatcagcaat ttcttgagca tcttctggac gaccaaaaac atctagataa tggaaaacca
    45721 tatttccctc aatcttacct ggatcctcaa cgcggatatg atctggatct gtatacatac
    45781 tcattacttt tttacgcaaa gtatccgcat catcagctaa ataaatacca ttatttagtg
    45841 atttagacat tttagcattt ccatctaaac caggcaaacg ccctgctctc tcattttctg
    45901 gataaatacc ttccggctct accaagacat cacagttata tgcattgtta aaagaacgaa
    45961 caatttcacg agtttgctca atcattggtt tctgatctgt cccaacagga acataattag
    46021 ccttgaaagc tgtgatatca gctgcttgag cgattggata gaccaagaat cctgtcggaa
    46081 tgctttctcc aaatcctttc tgagaaatct ctgtcttgac tgttggattt cgctccaaac
    46141 gtgctaacga aactagattc atataataca tagacaactc agccaactct ggaatctggc
    46201 tttgaataaa aatagttgac ttatttggat ccaatccaac tgcaagataa tccaaagcca
    46261 catttccgat agactctaca atggtttgag gatctttggc atgatctgtc aaggcttgtt
    46321 ggtcagccaa gaacacaaac atatcatact tatcctcttc ctgtaataat actcgatttt
    46381 tgagacttcc aacataatgt ccaatatgca attttcctgt tggacggtct cctgttaaaa
    46441 taatgggttt agtcattttg ttctccttcg atatagtcct ttcaattata gcattttttt
    46501 aatgaaataa ccgtaattta tcaaaataaa tcagccttgc tttttacaga tttgtgtaaa
    46561 ggatactgta aatataattt acacaaaatt gacaaataaa aatttgaata tttctgtatt
    46621 ttctagtaga ataaatatat tacacatata ggagaaaaac attgcttaca gtatctgatg
    46681 tttcactacg ttttagtgat cgcaaacttt ttgatgatgt caatatcaaa tttacagaag
    46741 gaaatactta cggattaatc ggtgctaatg gtgccggaaa atcaaccttt ttaaaaattt
    46801 tagctggaga tatcgaacct actactggtc acatctctct tggtccagat gaacgtctct
    46861 ctgttcttcg tcaaaatcac tttgactacg aagatgaacg tgccattgat gtcgttatca
    46921 tgggaaatga aaaactttat agcatcatga aagagaaaga tgctatctac atgaaggaag
    46981 atttctcaga cgaggacggg gttcgtgctg ccgaactcga aggagagttt gccgaacttg
    47041 gaggttggga agcagagagt gaagcctctc aactacttca aaacctaaac attccagaag
    47101 aattacacta ccaaaacatg agcgaattgg ccaacggtga aaaagtaaag gttctcctcg
    47161 ccaaagcact ttttggtaaa ccagatgttc ttctcttgga cgagcctact aacggtttgg
    47221 atatccaatc gattacttgg ttagaagact tcttgattga ctttgataac acagttatcg
    47281 tagtatccca cgaccgtcac ttcttaaaca aagtttgtac tcacatggcc gaccttgact
    47341 ttggaaaaat caaactctat gtcggaaact acgacttctg gaaggaatct tctgagcttg
    47401 ctgctaaatt gctagcagac cgtaatgcta aagcagaaga aaaaattaaa caattgcaag
    47461 aattcgttgc tcgtttctct gccaatgctt ctaagtcaag gcaggcaaca tcacgtaaga
    47521 aaatgcttga taagattgag ctagaagaga ttgtaccatc tagtcgtaaa tatccattta
    47581 tcaactttaa agcggaacgt gagattggta atgatctctt gacagtagaa aatctaactg
    47641 taaagattga tggtgaaact atcttggata atattagttt catcttgcgt ccagatgata
    47701 agacagcact tattggacaa aatgatattc aaacgactgc attaattcgt gcaatcatgg
    47761 gagatattga ctatgaagga actgtcaagt ggggagttac aactagtcaa tcttacctac
    47821 caaaagataa ctcagctgat tttgcaggag gagaatcaat tcttgactgg ttgcgtcaat
    47881 tcgcaagtaa agaagatgat gacaatactt tcctacgtgg tttcctcggc cgtatgctct
    47941 tctctggaga tgaagttaac aaacctgtaa atgtcttgtc agggggagaa aaagttcgtg
    48001 tcatgctttc aaaactcatg ctcttaaaat caaatgtcct tgtacttgat gatccaacaa
    48061 atcacttgga cttggaatct atctcaagct tgaatgatgg attgaaaaac tttaaagaat
    48121 caatcatctt tgccagccat gaccacgagt ttattcaaac tttggctaac catatcattg
    48181 tcttatctaa aaatggcgtc attgaccgta tcgatgaaac ctacgatgaa ttcctagaaa
    48241 atgcagaagt acaagcaaaa gttaaagaac tttggaaaga ctaaataaaa cttcaaaact
    48301 cagttgggtt aaccaactga gttttctatc attctacgag gtaacatgaa atcattttta
    48361 aaaacatatc gaacctattt tatttctttc atcattcctg tagtgattat gtctggagta
    48421 tatctatctc aaggtatcta ctggaatagc gacaactctc ctctattagg agatggcttt
    48481 catcaatacg ttatttttga tgtagcctta cgaaatatcc tacatggaaa tagtagtctg
    48541 ttttacacct ttacaagtgg tctagggcta aacttctatg ccctatctag ttattacttg
    48601 ggtagttttc tcgcgcctct agtttacttt tttgatctaa cgaatatgcc agatgctgtc
    48661 tatctgacca ctctcttaaa atttggattg attggtctgt caaccttttt tagtttgaat
    48721 aaattgtttc aatctatccc tcagacttta aaactagcct tatctacttc ctatgctctg
    48781 atgagtttca ctgtcagtca attagagata aaaacctggc tagatgtttt tatcttgatt
    48841 cctttaatta taactggttt acatctactg ataactgaaa agaaactcct attgtacttt
    48901 acaagtctgt caatcttatt tattcaaaat tattattttg gatatatgac agtattgttt
    48961 cttattttct ggtatctctg tcaaatttcg tgggacttta agactcgaaa atcatctgtt
    49021 cttgatttca tagttatctc ctttttagct ggtatggcta gtttgattat gactcttccc
    49081 actctatttg atttacagac acatggggaa aaattgactg aagttacaaa gtttcaaact
    49141 gaaagtagct ggtatcttga tctctttgct aagcaattca ttggttcctt tgacacaaca
    49201 aagtatgggg ccatcccaat gatttttgtt ggactacttc cctttatttt gaccatttta
    49261 ttttttacgc tgaaatctat taagtttcac gtgaaactca tatatgtaat attctttgca
    49321 tttctaattg caagctttta catagaagct cttgacttat tttggcaagg catgcatact
    49381 ccaaacatgt ttttacatcg ctatgcttgg attttctcta ccttgttaat ttacacagca
    49441 gcagaagtct taaagcgtct gaaagaactt aaagtctgga attttttagt ttcgcttttt
    49501 cttgtagtag caggattttt agctaccatc tatctaaaat cgcattattc ttttttaaca
    49561 gatttgaata ttctgcttac tcttgaattt ttggttgtct attctctttt actccttgca
    49621 gttatcaaaa agtttatatc tgtgaatcta tttgccattc taatctcttt atttatactg
    49681 gttgaaatga gtttaaatgc ttcatctcaa atggacggaa ttgctaagga atggggattt
    49741 gcttctcgaa gtgcttatag tcgagatatc ccagctatgg aatctttctc aacatatatt
    49801 ggaaatcaat ttactcgtac tgaaaaacta caaactcaga caggaaatga cagtatgaaa
    49861 ttcaactaca atggaatctc tcaattttca tctgttcgaa atcgttcatc aagctctact
    49921 ttagataaac ttggttttaa atcctctggg actaatctca atctccgata tgcaaataat
    49981 agtattttgg ctgatagttt atttggtatc cagtacaata tctcagacag tcctattgat
    50041 aagtatggtt ttaaagatat ctatcaaaaa gataatctta ccctatatga aaatcaatac
    50101 tctcttccga ttgcagttgc tagtcaatct gtttacaatg atgtcaagtt caatgaacat
    50161 accttggata atcaggcctc atttttaaat caacttgcta acgtcaattt tgattatttt
    50221 tctccaatat cttatgaaaa aacagaaaaa atagaaaata ctaatgattt gattagtgtc
    50281 acaagttctt caaatgaaga tgcagcaatc cagtatcaaa ttgaagttcc agaaaacagc
    50341 caagtttatc tctctttcat aaaccttcac ttttctaacg ataaacaaaa gaaggttgac
    50401 atccttgtaa atggtgaaaa aaagactttt acaactgata atgtcttctc cttctttaat
    50461 ctaggatata ctaaagagaa aaaaactttc aatatcaatg ttagtttccc tggaaattca
    50521 caagtatcat ttgaatctcc taccttctat cgtttagata ccaaaacttt caccgaggca
    50581 attcaaaaaa ttaaagaaca acctgtcaca gtatcaactt ctaaaaacaa ggtttttgct
    50641 acatatgatg tccaacaaga tacatctatt ttcttcacca ttccttatga caaaggttgg
    50701 tctgcctacc aagatggtaa gaaaatagaa attaaacaag ctcaaactgg atttatgaaa
    50761 gttgacattc ccaaggggaa aggaactatt acactttcct tcattcccaa tggttttatt
    50821 actggagcaa tctgttcctt tacttctctc ttactatttg gaatctataa tcacagacga
    50881 aagtcatcta aggcataaaa aatcgaccag ttaatcggtc gattttttta atcttcttcc
    50941 attttcttat gttgataggc tagcatacct aaaccagtaa atagagctag tatgacagct
    51001 aggaaaatga cttgttgatg gagattgttt gtcgtaatcc cgaaactgaa tagctcattg
    51061 gtaaccaggg attaatagat ctaaagaaat catttgtcaa agcaagtgga taagtacctg
    51121 cacttgatgc taactgtagt aaaagcaaaa taagtgagaa gaaagctcct atacggctat
    51181 tccacgttgt taaagtggtc accatagaca tgaatactaa acttgttagg atgatgagaa
    51241 taaatattct catctcatga ttagcagtta aaccaataag atgaactcct ccatatacca
    51301 aaattcctgc caaaacagct ataataccat ttatttcagc tcgagatttc aaccaagccc
    51361 aacggctctc tggatgacgt cctgagaaac tttatcaaca cctgtagtat atgcgtttac
    51421 acctgatgca atcgactgac tggcaggaac taatttgcta gtaacatctc cttgtatctc
    51481 tgttaatcca cttgacaatc ctatcaaaga agtagaagta ataggtgata cttgattaga
    51541 ttgatttttt aaagtcgaaa gattagaaga ttgattttgt aagttttcta aacttccctg
    51601 taaatcttgt actaaagcta caattgactg agccgattga atactagcag ttaaattttg
    51661 agatacagaa tcacttatct cagtttgttg ctcacttgtc aatgattgat aagctgctgt
    51721 cgattgaata ttggataatg tagttgtttt ttcagataaa tcacttggta aagtcactac
    51781 catatagtaa tcgccatctt ccaatccctt ctttccttcc tcttcatcta caaaatgaaa
    51841 atccaaggtt ttattttctt ttaaattgga caccatgtct tttcctattg ccatagtatt
    51901 accattatag gaagcctctt tatcattatt tacaactgcc acaggtaagt cagacaattg
    51961 cccatatgga tcccacattg atgacaaaaa tatgatattg tacagatctg gaataagaga
    52021 aatcccgatc atgacaataa taaaggttgg ttttttttaa aattgctttc cattctttaa
    52081 acttagtttc tcctttttta aacatattgt ctaaaatttt gatataatag attatacatt
    52141 aaaaaatcta aattacaaga taaaaaatct atttttagac atatagtcta atttgtttac
    52201 aaggaggaaa tatgcaagaa agtaacaaac gcttaaaaac aaagcgaact attgaaaatg
    52261 ctatggtaca attactgatg gaacagccat ttgataaaat ttctactgtc aaattagtag
    52321 aaaaagccgg aattagtcgt tccagcttct atactcacta taaggataag tatgatatga
    52381 ttgagcacta tcaaagcaag ctattccata catttgaata tatttttcaa aaacatgctc
    52441 atcacaaaag agacgctatt ttagaagttt ttgaatatct agagtcagaa ccacttctgg
    52501 ctgcccttct ttctgaaaat gggactaaag aaatccaaaa tttcttacga aataaacttc
    52561 atatcatgct tagtacagat ttacaaaagc gatttatgca actgaatcta aataccaccg
    52621 aattagaata tagtagcatc tatctaactc atgcactttt tggtgtctgc caaacttgga
    52681 ttgcacatgg aaaaaaagaa agttctcaag aaataacaga cttccttatg aaaatgcttg
    52741 gtgatacaaa ttgatacaaa aagaggaaca cagctgtgtt cccttttatc tatactccgc
    52801 cagtaggact cgaacctacg acatcatgat taacagtcat gcgctactac caactgagct
    52861 atggcggata aaatagtccg tacgggattc gaacccgtgt taccgccgtg aaaaggcggt
    52921 gtcttaaccc cttgaccaac ggaccttcta tctgtagcag atataaccat tatatcaatt
    52981 tcttgctaat tgtcaatcac ttttgagatt ttttctctaa aatatctttt aattttctaa
    53041 tttttaatct tgaaatagga caacgatggt cttcatagaa aacaatttct aagttttttc
    53101 gatcaatttc tctgatattg cctatattta ccaaaaatga cttgtgagga gaataaaatc
    53161 gctgagtatg tttgtccttt tcctgaatat ctgtcatggt accataaaac tcttttgcaa
    53221 aattcttacc aataatgcgc aatttatgag atacccctgt tgtttcaata tacaaaatat
    53281 catggtaagg aatttttaaa tcatttccct tgtaattgta gtcgaaataa tctacaacat
    53341 cttcattttc aagtaacata ctcttcgtgt agaagatatt ttgctcaatt ctcttcttaa
    53401 acatctcatc attgatatcc ttatcaacaa aatctagggc tgatacctga tatttatagg
    53461 ttagagtcgc aaactctgat cgactagtga taaagacgat aatagcgtaa ggattgtaat
    53521 gacgaatgag ctgagccact tcaaatccct ttttctcaat tccatgaata tcgatatcta
    53581 ggaaataaag ctgatttact tcatcatttt caatgtattc ttcaaattca cggacttttc
    53641 ccgttgtctt gtatgatatt ggaatattcg attctttcga aatttcatcc aatattctct
    53701 ctagtctcac ttgatgttca ataacatctt ctaaaattaa aactttcatt caaattccct
    53761 cttaaatcta atgatttgtc taaatgtact gccttccatc tctgtttcta aaataatatt
    53821 gttgtactta tctagtagtt ctttcacatt atttaatccg actccgcgat ttcttccctt
    53881 agtggagaat cctaaggcaa atagatctcc tgaaggagtc atcgtcattt tacatgaatt
    53941 ctgaatcaca ataactgttt cagtttccat cttaataact gctacttcca tctgcttttt
    54001 atagctatca gccgatcctt cgacagcatt attcaataaa acgctcatga tacgaaccaa
    54061 atccaatagt tcaattggaa gcttggtaat cgtatctttt acttccagtg taaactctac
    54121 accattattt cgagcataga caattgactg agcaaccaaa cttcgtaaag ctgagtcttc
    54181 tatgttgttc aaatcaaagt aagtgtactt atctgaacgc aatttatgat ttgctttgac
    54241 taaaacttca ttgtaaattc tgtcaatttc ctgtaaatta ccactgtcaa ttgccatctg
    54301 catgctgaca agcattccag cataatcatg tcgaaaacca cggatttcat tatacagacc
    54361 aacaatttca tctgtgtaat tctgtaaatg tttctgttca aatttcttct gcttcaaagc
    54421 aatctctttc tccatttgaa ctttatgaga attcattgca aagaaggtca aaaggagaga
    54481 gataaagaca atagatgaca aaatacttcc aaaactattc aaatgtttaa tcgtacttac
    54541 catatctgaa acgaaagata caatatgtag caatagtaaa gcaaaaaata cttttttcaa
    54601 gaaaggataa aggtagtcct cgtcaaaata ggctagttcc aaatggaaat agtaaatgat
    54661 ttttaatgta acaaaatagg ttaacaccgt cacaacgaaa aagaatggga aatgatattg
    54721 taaaacaaaa ttatctcctg ttatagagga gaaagttacg gacagaaagt tatgagtgct
    54781 ctcatataaa agagatagta gtaaacttag gaatagtcct ctatccctct catactgttt
    54841 catccatcga aaataggaat ataatcccaa aggaaataaa aatctttcaa tccctaaccc
    54901 atctaaatat agaatatata agggaaaatc aaatactatt tctgttagta atgtataagc
    54961 accaa
//
LOCUS       DAVLDI010000005        54960 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLDI010000005 DAVLDI010000000
VERSION     DAVLDI010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54960
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.005"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            720..1712
                     /locus_tag="VXD01_000291"
     CDS             720..1712
                     /locus_tag="VXD01_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0600751.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VXD01_000292"
     CDS             1714..2532
                     /locus_tag="VXD01_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV0600752.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VXD01_000293"
     CDS             2534..3319
                     /locus_tag="VXD01_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0600753.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3417..3635
                     /locus_tag="VXD01_000294"
     CDS             3417..3635
                     /locus_tag="VXD01_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV0600754.1"
                     /translation="MKDLPEWFGIPESTQTYIEGTTTLQVWTAYQESDLTGFVSLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3620..3817
                     /locus_tag="VXD01_000295"
     CDS             3620..3817
                     /locus_tag="VXD01_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0600755.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(4142..4504)
                     /locus_tag="VXD01_000296"
     CDS             complement(4142..4504)
                     /locus_tag="VXD01_000296"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600756.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDGTDVVSSKHCFEVVDGTDVVS
                     SKHCFEVVDGTDVVSSKHCFEVVDGTDVVSSKHCFEVVDRTDEVSSKHCFEVVDRTDE
                     VSNHTHGKAALTWFEEIF"
     gene            4737..11171
                     /locus_tag="VXD01_000297"
     CDS             4737..11171
                     /locus_tag="VXD01_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV0600757.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARVKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDDRIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYINGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNLNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
     gene            11798..12274
                     /locus_tag="VXD01_000298"
     CDS             11798..12274
                     /locus_tag="VXD01_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0600758.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            12312..12617
                     /locus_tag="VXD01_000299"
     CDS             12312..12617
                     /locus_tag="VXD01_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0600759.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            12665..14140
                     /locus_tag="VXD01_000300"
     CDS             12665..14140
                     /locus_tag="VXD01_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV0600760.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVLYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            14166..14243
                     /locus_tag="VXD01_000301"
                     /pseudo
     CDS             14166..14243
                     /locus_tag="VXD01_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14445..21146
                     /locus_tag="VXD01_000302"
     CDS             14445..21146
                     /locus_tag="VXD01_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV0600761.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTESRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDSQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLVTVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELSVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKSGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLYFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDYSENRRWTNWSARPSTNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPSKLVLERYVGPGFEVPTYYSNYQAYESGHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGDDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVATVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(21393..22249)
                     /locus_tag="VXD01_000303"
                     /pseudo
     CDS             complement(21393..22249)
                     /locus_tag="VXD01_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125496.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(22461..22820)
                     /locus_tag="VXD01_000304"
     CDS             complement(22461..22820)
                     /locus_tag="VXD01_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV0600762.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            22912..23868
                     /locus_tag="VXD01_000305"
                     /pseudo
     CDS             22912..23868
                     /locus_tag="VXD01_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            23852..24409
                     /locus_tag="VXD01_000306"
     CDS             23852..24409
                     /locus_tag="VXD01_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0600763.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            24402..24656
                     /locus_tag="VXD01_000307"
     CDS             24402..24656
                     /locus_tag="VXD01_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600764.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            24668..26722
                     /locus_tag="VXD01_000308"
     CDS             24668..26722
                     /locus_tag="VXD01_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV0600765.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRNRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            26901..27761
                     /locus_tag="VXD01_000309"
     CDS             26901..27761
                     /locus_tag="VXD01_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV0600766.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            27972..28682
                     /gene="ccdA2"
                     /locus_tag="VXD01_000310"
     CDS             27972..28682
                     /gene="ccdA2"
                     /locus_tag="VXD01_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV0600767.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLVFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            28702..29268
                     /locus_tag="VXD01_000311"
     CDS             28702..29268
                     /locus_tag="VXD01_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV0600768.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            29279..30391
                     /gene="msrB"
                     /locus_tag="VXD01_000312"
     CDS             29279..30391
                     /gene="msrB"
                     /locus_tag="VXD01_000312"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0600769.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            30659..31396
                     /locus_tag="VXD01_000313"
     CDS             30659..31396
                     /locus_tag="VXD01_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0600770.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            31393..33084
                     /locus_tag="VXD01_000314"
     CDS             31393..33084
                     /locus_tag="VXD01_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0600771.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            33200..33763
                     /locus_tag="VXD01_000315"
     CDS             33200..33763
                     /locus_tag="VXD01_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV0600772.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            33785..39487
                     /locus_tag="VXD01_000316"
     CDS             33785..39487
                     /locus_tag="VXD01_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0600773.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETKTAKGTQEEGKEGQAPVQEVNPEYKVTTGTVEKSTESELDFTTEV
                     VPDDTKYVDEEVVERQGSKGVQVTKTTYETVEVVETDKVLSTTTEVKTPVVPKVVKKG
                     TKPVEGTAVETREEVIPFATKEQEDGTLKRGTRQVAQEGVNGKKQITETYKTIRAEKT
                     NEAPTVEETVLQAPQDEIIKKGTKGLEKPTLEWVKTDKDVLKKSATASYTLNKPDGVE
                     IKSIKVALKDNTGTVIKEVTVEENNLNVTLDNLKYYQGYTLSTTMVYNRGEGEETETL
                     EDKEVQLDLKKVEIKNIKETSLMSVDDAGVETDKSLLTEKPTDVAPLYLRVTTHDNKV
                     TRLAVDKIEEVEEDGKTLYKVTAKAPDLVQRNADNTLSEEYVHYFEKQLPKIGNVYYN
                     FNELITDMQKTPNGEFKLGADLNAVNVPTPNKSYVTAKFTGKLYSEGDKHYTIHNLAR
                     PLFAQAENAHIHDINLGNVNINMPWANKTAPLGEMFKKSTIENVKVTGNVVGNNDVTG
                     MVNKLDESDMRNVAFIGNITSVGSAGWWSGGLVSESWRSNTDNSYIDTTIKGNKAKVG
                     GLIAKLNHGADPRDVGARGRLKNSVAKGTIDVRDPQETGGLLHSNWSWGLAENNITMM
                     KVKNGGEILYGSRDAEDDDYFGANWVRNNNAFVNGISEGKQSYSRSSRWKGISEDEAK
                     TRIAKMGITAHEYEITQHLTDKLNRAAFKEDTYKTTQDYKTERELAYRNIEKLQPFYN
                     KEWIINQGNKLTDGSNLMIKEVLSVIGMKNGQFVTDLSDIDKIMIHYADGTKEEKTVT
                     RKADSKVQQIREYSVEGLGDVVYTPNMVEKDRAQLITDIKAKLDSVQLISPEVRNLMD
                     KRGKAHENTDERRNGYIRNLFLEESLDEVKGNLDKLVKALVENEDHQLNGDEAAMKAL
                     VKKVEDNKAKIMLGLAYLNRYYGFKYDEKSMKDIMMFKPDFYGKNVSVLDFLIRVGSR
                     EHNIKGNRTLEAYREVIGGTIGIGELNGFLNYNMRLFTEETDINTWYKKAVSHTNYIV
                     EKQSSNPAFANKKYRLYENLNNGEHGKYILPLLTTKKAHMFLISTYNTLAFSAFEKYG
                     KNTEAEREAFKKEIDLRAQEQINYLDFWSRLAADNVRDRLLKSENMVPSAIWDNQEVP
                     GHGWADRMGHNKNGDYAPVREFYGPTGKWHGYNGTGAYAYIFTNPQNSEAVYYIISSM
                     ISDFGTSAFTHETTHINDRMAYLGGWRHREGTDVEAFAQGMLQSPAVSSPNGDYGALG
                     LNMAYKRENDGNQWYNYDSNKLDSRAKIDHYMKNYNEALMMLDHLEADAVIAKNNGDN
                     NKWFKKMDKKWRENANRNGLVGQPHQWDLLRDLNEEENKKKLTSIDDLVDGNYVTKHN
                     MPGNKHYRAEGFDTAYQTVNMMAGIYGGNTSKSAVGSISFKHNTFRMWGYFGYLDGFV
                     GYASNKYKDAANKENKGLLGDDFIIKKVSDGKFDSLEAWKKEWFKEVKAKGEKGFVAI
                     EIDGKTITNYAELRELFDKAVEADLKAGNSNQTVALKEKVYKQLLQKSDGFVGNLFKA
                     "
     gene            39562..41283
                     /gene="pabB"
                     /locus_tag="VXD01_000317"
     CDS             39562..41283
                     /gene="pabB"
                     /locus_tag="VXD01_000317"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV0600774.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKVPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            41284..41901
                     /locus_tag="VXD01_000318"
     CDS             41284..41901
                     /locus_tag="VXD01_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0600775.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            41951..42941
                     /locus_tag="VXD01_000319"
                     /pseudo
     CDS             41951..42941
                     /locus_tag="VXD01_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            43076..44035
                     /locus_tag="VXD01_000320"
     CDS             43076..44035
                     /locus_tag="VXD01_000320"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV0600776.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            44133..44972
                     /locus_tag="VXD01_000321"
     CDS             44133..44972
                     /locus_tag="VXD01_000321"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV0600777.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(45020..45190)
                     /locus_tag="VXD01_000322"
     CDS             complement(45020..45190)
                     /locus_tag="VXD01_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV0600778.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            45311..46195
                     /gene="miaA"
                     /locus_tag="VXD01_000323"
     CDS             45311..46195
                     /gene="miaA"
                     /locus_tag="VXD01_000323"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV0600779.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPYEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            46188..47426
                     /gene="hflX"
                     /locus_tag="VXD01_000324"
     CDS             46188..47426
                     /gene="hflX"
                     /locus_tag="VXD01_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV0600780.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            47419..48042
                     /locus_tag="VXD01_000325"
     CDS             47419..48042
                     /locus_tag="VXD01_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV0600781.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            48057..48986
                     /locus_tag="VXD01_000326"
     CDS             48057..48986
                     /locus_tag="VXD01_000326"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV0600782.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            49007..49762
                     /locus_tag="VXD01_000327"
     CDS             49007..49762
                     /locus_tag="VXD01_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0600783.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(49816..50724)
                     /locus_tag="VXD01_000328"
     CDS             complement(49816..50724)
                     /locus_tag="VXD01_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV0600784.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            50788..51057
                     /locus_tag="VXD01_000329"
     CDS             50788..51057
                     /locus_tag="VXD01_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV0600785.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            51057..51437
                     /locus_tag="VXD01_000330"
     CDS             51057..51437
                     /locus_tag="VXD01_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0600786.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNKEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            51526..51753
                     /locus_tag="VXD01_000331"
     CDS             51526..51753
                     /locus_tag="VXD01_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600787.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(51793..52518)
                     /locus_tag="VXD01_000332"
     CDS             complement(51793..52518)
                     /locus_tag="VXD01_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0600788.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            52680..54521
                     /gene="typA"
                     /locus_tag="VXD01_000333"
     CDS             52680..54521
                     /gene="typA"
                     /locus_tag="VXD01_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV0600789.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            54541..54795
                     /locus_tag="VXD01_000334"
     CDS             54541..54795
                     /locus_tag="VXD01_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV0600790.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
BASE COUNT        17330 a         9837 c        12018 g        15775 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat tgatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cgatgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aatttcacaa tccataggca aactcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagcaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccagact cgctctttca taagcgtatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctgtc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc gggaagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tttccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ttggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aatttctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagga acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaggc agttgtcgct gagattttga
     3421 aggatttgcc agaatggttt ggaatcccag aaagcacaca aacctatata gaaggaacca
     3481 cgacactgca agtttggacc gcctatcagg agagtgattt gactggattt gtaagcttat
     3541 cctattcgag tgaagattgt gcagagattg attgtctcgg cgtaaaaaag cttatcaagg
     3601 tagaaaaatt gggagccaat tgcttgctac tttagagagt gaagctcgta aaaaagttgg
     3661 ttatctgcag gtcaaaacag tggcagaagc ttctaataaa gattatgatc gaacaaatga
     3721 cttttatcga ggtcttggct ttaaaaagtt agagattttt cctcaactat ggaatccgca
     3781 aaatccttgt cagattttga ttaaaaagct tgaataatat tacttgacat ctatttttta
     3841 ttctcagagt gctatactgt aagtgtaatc gccgatttag ctcagttggt agagcaaggc
     3901 actcgtaaag cctaggttat aggtagataa acgactgagg agttgaaaaa atagataggt
     3961 agaagataac cgttaagcct tattcttagc ggttatttat attgtttaat agcgctgata
     4021 tttcatcaat tatgcctgtt ttcgtgtttc cggtagttgt tcaagtttat tgctactatt
     4081 tttgatggta tgaatgtgct tataatgtat cccggttaac gaaagttttg gacttatact
     4141 cttagaaaat ctcttcaaac cacgtcaacg ccgccttgcc gtgcgtatgg ttactgactt
     4201 cgtcagttct atccacaacc tcaaaacagt gttttgagct gacttcgtca gttctatcca
     4261 caacctcaaa acagtgtttt gagctgacta cgtcagttcc atctacaacc tcaaaacagt
     4321 gttttgagct gactacgtca gttccatcta caacctcaaa acagtgtttt gagctgacta
     4381 cgtcagttcc atccacaacc tcaaaacagt gttttgagct gactacgtca gttccatcta
     4441 caacctcaaa acagtgtttt gagcaacctg cggctagttt cctagtttgc tctttgattt
     4501 tcattgagta ctaatcttac tttttaacgt gtgctaaaaa ataaattaat gcatgttaat
     4561 ttttcttgaa ttaaattttt ttaaatgata tactgttttt atagagagat aacaattata
     4621 tataaatgta ctactctatt tcctagataa tacttagtaa aactttttat aacaaaggct
     4681 agcaaagtta aagtttatta tctattggaa gttaaataaa tatgtaagga attaaaatga
     4741 aaaaaagtac agtattgtca ttaaccacag ctgcagttat tttagcagcc tatgccccta
     4801 atgaggtagt cttagcagac acatctagct ctgaagatgc tttaaacatc tctgataaag
     4861 aaaaagtagt attagataag gaaacagaaa ataaagagaa acatgaagat attcataatg
     4921 ctatagaaac ttcacaggat tttaaagaga agaaaacagc agtcattgag ggaaaagaag
     4981 ttgttagtaa aaatcctgtg acagacaata acactagcaa tgaagaagca agagtcaaag
     5041 aagattccaa tcaatcccaa ggagatcata cggactcatt tgtgaataaa aacacagaaa
     5101 atcccaaaaa agaagataaa gttgtctata ttgctgaatt taaagataaa gaatctggag
     5161 aaaaagcaat caagcaacta tccaatctta agaatacaaa agttttatat acttatgata
     5221 gaatttttaa cggtagtgcc atagaaacaa ctccagataa cttggacaaa attaaacaaa
     5281 tagaaggtat ttcatcggtt gaaagggcac aaaaagtcca acccatgatg aatcatgcca
     5341 gaaaggaaat tggagttgag gaagctattg attacctaaa gtctatcaat gctccgtttg
     5401 ggaaaaattt tgatggtaga ggtatggtca tttcaaatat cgatactgga acagattata
     5461 gacataaggc tatgagaatc gatgatgatg ccaaagcctc aatgagattt aaaaaagaag
     5521 acttaaaagg aactgataaa aattattggt tgagtgataa aatccctcat gcgttcaatt
     5581 attataatgg tggcaaaatc actgtagaaa aatatgatga tggaagggat tattttgacc
     5641 cacatgggat gcatattgca gggattcttg ctggaaatga tactgaacaa gatatcaaaa
     5701 actttaacgg catagatgga attgcaccta atgcacaaat tttctcttac aaaatgtatt
     5761 ctgacgcagg atctgggttt gcgggtgatg aaacaatgtt tcatgctatt gaagattcta
     5821 tcaaacacaa cgttgatgtt gtttcggtat catctggttt tacaggaaca ggtcttgtag
     5881 gtgagaaata ttggcaagct attcgggcat taagaaaagc aggcattcca atggttgtcg
     5941 ctacgggtaa ctatgcgact tctgcttcaa gttcttcatg ggatttagta gcaaataatc
     6001 atctgaaaat gaccgacact ggaaatgtaa cacgaactgc agcacatgaa gatgcgatag
     6061 cggtcgcttc tgctaaaaat caaacagttg agtttgataa agttaacata ggtggagaaa
     6121 gttttaaata cagaaatata ggggcctttt tcgataagaa taaaatcaca acaaatgaag
     6181 atggaacaaa agctcctagt aaattaaaat ttgtatatat aggcaagggg caagaccaag
     6241 atttgatagg tttggatctt aggggcaaaa ttgcagtaat ggatagaatt tatacaaagg
     6301 atttaaaaaa tgcttttaaa aaagctatgg ataagggtgc acgcgccatt atggttgtaa
     6361 atactgtaaa ttactacaat agagataatt ggacagagct tccagctatg ggatatgaag
     6421 cggatgaagg tactaaaagt caagtgtttt caatttcagg agatgatggt gtaaagctat
     6481 ggaacatgat taatcctgat aaaaaaactg aagtcaaaag aaataataaa gaagatttta
     6541 aagataaatt ggagcaatac tatccaattg atatggaaag ttttaattcc aacaaaccga
     6601 atgtaggtga cgaaaaagag attgacttta agtttgcacc tgacacagac aaagaactct
     6661 ataaagaaga tatcatcgtt ccagcaggat ctacatcttg ggggccaaga atagatttac
     6721 ttttaaaacc cgatgtttca gcacctggta aaaatattaa atccacgctt aatgttatta
     6781 atggcaaatc aacttatggc tatatgtcag gaactagtat ggcgactcca atcgtggcag
     6841 cttctactgt tttgattaga ccgaaattaa aggaaatgct tgaaagacct gtattgaaaa
     6901 atcttaaggg agatgacaaa atagatctta caagtcttac aaaaattgct ctacaaaata
     6961 ctgcgcgacc tatgatggat gcaacttctt ggaaagaaaa aagtcaatac tttgcatcac
     7021 ctagacaaca gggagcaggc ctaattaatg tggccaatgc tttgagaaat gaagttgtag
     7081 caactttcaa aaacacggat tctaaaggtt tggtaaactc atatggttcc atttctctta
     7141 aagaaataaa aggtgataaa aaatacttta caatcaagct tcacaataca tcaaacagac
     7201 ctttgacttt taaagtttca gcatcagcga taactacaga ttctttaact gacagattaa
     7261 aacttgatga aacatataaa gatgaaaaat ctccagatgg taagcaaatt gttccagaaa
     7321 ttcacccaga aaaagtcaaa ggagcaaata tcacatttga gcatgatact ttcactatag
     7381 gcgcaaattc tagctttgat ttgaatgcgg ttataaatgt tggagaggcc aaaaacaaaa
     7441 ataaatttgt agaatcattt attcattttg agtcagtgga agaaatggaa gctctaaact
     7501 ccaacgggaa gaaaataaac ttccaacctt ctttgtcgat gcctctaatg ggatttgctg
     7561 ggaattggaa ccacgaacca atccttgata aatgggcttg ggaagaaggg tcaagatcaa
     7621 aaacactggg aggttatgat gatgatggta aaccgaaaat tccaggaacc ttaaataagg
     7681 gaattggtgg agaacatggt atagataaat ttaatccagc aggagttata caaaatagaa
     7741 aagataaaaa tacaacatcc ctggatcaaa atccagaatt atttgctttc aataaccaag
     7801 ggatcaacgc tccatcatca agtggttcta agattgctaa catttatcct ttagattcaa
     7861 atggaaatcc tcaagatgct caacttgaaa gaggattaac accttctcca cttgtattaa
     7921 gaagtgcaga agaaggattg atttcaatag taaatacaaa taaagaggga gaaaatcaaa
     7981 gagacttaaa agtcatttcg agagaacact ttattagagg aattttaaat tctaaaagca
     8041 atgatgcaaa gggaatcaaa tcatctaaac taaaagtttg gggtgacttg aagtgggatg
     8101 gactcatcta taatcctaga ggtagagaag aaaatgcacc agaaagtaag gataatcaag
     8161 atcctgctac taagataaga ggtcaatttg aaccgattgc ggaaggtcaa tatttctata
     8221 aatttaaata tagattaact aaagattacc catggcaggt ttcctatatt cctgtaaaaa
     8281 ttgataacac cgcccctaag attgtttcgg ttgatttttc aaatcctgaa aaaattaagt
     8341 tgattacaaa ggatacttat cataaggtaa aagatcagta taagaatgaa acgctatttg
     8401 cgagagacca aaaagaacat cctgaaaaat ttgacgagat tgcgaacgaa gtttggtatg
     8461 ctggcgccgc tcttgttaat gaagatggag aggttgaaaa aaatcttgaa gtaacttacg
     8521 caggtgaggg tcaaggaaga aatagaaaac ttgacaaaga cggaaatacc atttatgaaa
     8581 ttaaaggtgc gggagattta aggggaaaaa tcattgaagt cattgcatta gatggttcta
     8641 gcaatttcac aaagattcat agaattaaat ttgctaatca ggctgatgaa aaggggatga
     8701 tttcctatta tctagtagat cctgatcaag attcatctaa atatcaaaag cttggcgaga
     8761 ttgcagaatc taaatttaaa aatttaggaa atggaaaaga gggtagtcta aaaaaagata
     8821 caactggggt agaacatcat catcaagaaa atgaagagtc tattaaagaa aaatctagtt
     8881 ttactattga tagaaatatt tcaacaatta gagactttga aaataaagac ttaaagaaac
     8941 tcattaaaaa gaaatttaga gaagttgatg attttacaag tgaaactggt aagagaatag
     9001 aggaatacga ttataaatac gatgataagg gaaatattat tgcttatgac gatggtagtg
     9061 ccttacaata tgaaactgaa aaacttgacg aaataaaatc aaaaatttat ggtgttctaa
     9121 gcccatctaa agatggacac tttgaaattc ttggaaagat aagcaatgtt tctaaaaatg
     9181 ccaaggtata ttatggaaat agctataaat cgatagaaat caaagcgact aagtatgatt
     9241 cacattcaaa aacgatgata tttgatttat acgctaatat taatgatatt gtagatggat
     9301 tagcttttgc tggagatatg agattatttg ttaaagatga tgatcgaata aaagctgaaa
     9361 ctaagattag aatgcctgaa aaaaataagg aaactaaagc agaatatccc tatgtatcaa
     9421 gttatgggaa tgtaatcgaa ttaggagaag gagatctttc aaagaacaaa ccagacaatt
     9481 taactaaaat ggaatctggt aaaatctatt ctgattcaga aaaacaacaa tatctgttaa
     9541 aggataacat cattctaaga aaaggctatg cactaaaagt gactacctat aatcctggaa
     9601 aaacggatat gttagaagga aatggagtct atagcaagga agatatagca aaaatacaaa
     9661 aggccaatcc taatctaaga gtcctttcag aaacaacaat ttatgctgat agtagaaatg
     9721 ttgaagatgg aagaagtacc caagctgtat taatgtcggc tttggacggc tttaacatta
     9781 taaggtatca agtgtttaca tttaaaatga acgataaagg ggaagctatc gataaagacg
     9841 gaaatcttgt gacagattct tctaaacttg tattatttgg taaggatgat aaagaataca
     9901 ctggagagga taagtccaat gtagaagcta taaaagaaga tggttccatg ttatttattg
     9961 ataccaaacc agtaaacctt tcaatggata agaactactt taatccatct aaatctaata
    10021 aaatttatgt acgaaatcca gaattttatt taagaggtaa gatttctgat aagggtggtt
    10081 ttaactggga attgagagtt aatgaatcgg ttgtagataa ttatttaatc tacggagatt
    10141 tacacattga taacactaga gattttaata ttaagttgaa tgttaaagac ggtgacatca
    10201 tggactgggg aatgaaagac tataaagcaa acggatttcc agataaggta acagatatgg
    10261 atggaaatgt ttatcttcaa actggctata gcgatttgaa tgctaaagca gttggagtcc
    10321 actatcagtt tttatatgat aatgttaaac ccgaagtaaa cattgatcct aagggaaata
    10381 ctagtatcga atatgctgat ggaaaatctg tagtctttaa catcaatgat aaaagaaata
    10441 atggattcga tggtgagatt caagaacaac atatttatat aaatggaaaa gaatatacat
    10501 cgtttgatga tattaaacaa ataacagaca agacactaaa cattaagatt gttgtaaaag
    10561 attttgcaag aaatacaacc gtaaaagaat tcattttaaa taaagatacg ggagaggtca
    10621 gtgaattaaa acctcatagg gtaactgtga ccattcaaaa tggaaaagaa atgagttcaa
    10681 cgatagtgtc ggaagaagat tttattttac ctgtttataa gggtgaatta gaaaaaggat
    10741 accaatttga tggttgggaa atttctggtt tcgaaggtaa aaaagacgct ggctatgtta
    10801 ttaatctatc aaaagatacc tttataaaac ctgtattcaa gaaaatagag gagaaaaagg
    10861 aggaagaaaa taaacctact tttgatgtat cgaaaaagaa agataaccca caagtaaacc
    10921 atagtcaatt aaatgaaagt cacagaaaag aggatttaca aagagaagat cattcacaaa
    10981 aatctgattc aactaaggat gttacagcta cagttcttga taaaaacaat atcagtagta
    11041 aatcaactac taacaatctt aataagttgc caaaaactgg aacagcaagc ggagcccaga
    11101 cactattagc tgccggaata atgtttatag taggaatttt tcttggattg aagaaaaaaa
    11161 atcaagatta agataaaagc tatagaaaaa aatggtttat gtactgagat tagatagtga
    11221 ggtgatgaca tagttttgtg aaaacagcca tttataactc aattatttag tttacttcac
    11281 tattgatact atttggagtt attaatggac ttagtttaga taactaatga attgattgaa
    11341 agggttagta ttgacaatat tggtcatatt gattagaaaa tagagtctat caaaatttaa
    11401 aggctaatag aggtgatgag acaatttcaa ggaattaagt agcgtttggt tgcttaattc
    11461 ctttttattt ggaaggaagt ttttcgtaac cgcccaataa cgaagtctat tggacggtta
    11521 cgatatgatc actgacttcg tcagtcttat ctacaacctc aaaactgtgt tttgagcaac
    11581 ctgcggctag cttcctagct tactctttga ttttcattga gtattagaac agaaaaaatg
    11641 cttggagtat ttgtttgtgt gtttattttt atataacaaa ctataaacaa aacaaaaata
    11701 taaaaaaaga gacaaaaaag aacagaaagt aattgacaac ggtttcatat agtgttatac
    11761 ttatggcata aagttaatgg aaagaaggga aaaacttatg gtattagatt atttctttga
    11821 caaaaacctt gtgttttgct tagaagcgga taatcaagaa caactctttg atcaggttgc
    11881 aactttattg gaagaacgag aaattgtcac tccaacttat cgtgaagctt tgatcacgcg
    11941 tgaaaagtca tttccaactg gtttagatat ggaatttcta ggaaaggact tgccaaatgt
    12001 agcgattcct catacagata ttgttcataa tctagctgag aaagtggtgg ttgttcgatt
    12061 agaaaaacca gtaacttttc acaatatgat agctcctgat aaggaagtag aagtatcctt
    12121 gctcttcttt atcatcaata actcaagttc aagtcaaaca aatattctgg ctcagttgat
    12181 ggactttttc acaggaaatg gacatcttga agacctatca aaaatttccg aaccagaaaa
    12241 actttatgct tacattgctg aagcaaccgc ttaatcttgt ctattaaaaa ataaaatcgg
    12301 aggaaatcca aatgattaaa attcttgctg cctgcggtgc aggtgttaac tcaagtcacc
    12361 aaattaaaag tgctctagaa gaagaacttt caaaccgtgg ttatgatgtt cactgtgatg
    12421 cagtcatggt gaaagatgta aacgaagacc ttatgaaagg ttacgatatc tttacaccaa
    12481 tcgctgcaac agaccttggt tttgaaccag gtatcccagt tatcgaagct gggccaatct
    12541 tattccgtat cccagcaatg agcgctccag tatttgacaa tattgaagca gctattaaag
    12601 aacatggatt aagctaattc taatttgtta acattcatat aacataaaaa agggaggaac
    12661 tgttatggat gcaatctttg acctaatcgg aaaggttttc aatcccatct tagaaatggg
    12721 tggacctgtc atcatgttaa tcattttgac agtattggct ttactttttg gagtgaaatt
    12781 ctccaaagcg cttgaaggtg gtatcaaact tgccatcgct cttacaggta tcggtgctat
    12841 catcggtatg ctaaatggtg ctttctcagc atcacttgca aaattcgttg aaaacactgg
    12901 tatacaattg agtattaccg acgttggttg ggcaccactt gcaacaatca cttggggttc
    12961 tgcttggaca ctatacttct tgctcatcat gttgattgtc aacgtagtga tgcttgctat
    13021 gaagaaaacc gatacacttg atgtcgatat ctttgatatc tggcacttgt ctatcacagg
    13081 tctcttgatt aaatggtatg ctgataacaa tggtgtgagt caaggggttt cactctttat
    13141 tgctacagca gctatcgtcc ttgtcggtgt gttgaaaatt atcaactctg acttgatgaa
    13201 acctacattt gatgaccttc ttaacgcccc aagttcatca ccaatgacat caactcacat
    13261 gaactacatg atgaacccag ttatcatggt tttggataag atttttgaaa aattcttccc
    13321 aggccttgat aaatatgact ttgatgctgc taaattgaac aagaaaatcg gtttctgggg
    13381 atctaaattc ttcatcggtt tcatccttgg tatcgttatc ggtattatgg gaactccaca
    13441 tccaattgca ggtgttgcag atgcagataa atggcgtctt gttatcaaag gatggttgtc
    13501 tcttggtttg actgccggtg tatctttgga actcttctca cttatcggtt catggttcat
    13561 cgcagccgta gaaccactat cacaaggtat tacaaacgtt gctactaaac gtcttcaagg
    13621 acgtaaattc aatatcggtc ttgactggcc attcatcgct ggtcgtgctg aaatctgggc
    13681 ttgtgccaac gtacttgcac caatcatgtt gattgaagca gtgcttcttt caaaagttgg
    13741 aaatggtatc ttgccacttg caggtatcat cgctatgggt gttactccag ctctcttggt
    13801 tgtaactcgt ggtaaattgc tccgtatgat tatcttcgga acactcttgt tgccactctt
    13861 ccttctttca ggtacactta ttgcaccatt tgcaacagaa cttgctaaag gtgtaggtgc
    13921 cttcccagaa ggtgtgagcc aaactcaatt gattactcac tctactcttg aaggaccaat
    13981 cgaaaaactt cttggttgga caattggtaa cactacaact ggtgatatca aagcaatcct
    14041 tggtgcagta gtcttccttg tattatatat cggtatcttt gcttggtaca gaaaacaaat
    14101 gatcaaacgt aacgaagagt acgcagcaaa agcaaaataa tgcgctccta taaaatataa
    14161 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacacagtt
    14221 ttgaggttgt agataagact gacgaagtca gctcaaaaca tggttttgag gttgtagatg
    14281 aaactgacga agtcagtaat catatctacg gcaaggcgac actgacgaag tttgaattgg
    14341 attttcgcag agtgtaaatt gttgaaacta ggttgtcata ccatgtatac tacttgggtt
    14401 ttggcagtag ctaactgcac taaatataat ataaggaggg ttttatgggg aaaggtcatt
    14461 ggaatcggaa aagagtttat agcattcgta agtttgctgt gggagcttgc tcagtaatga
    14521 ttgggacttg tgcagttcta ttaggaggaa atatagctgg agaatctgta gtttatgcgg
    14581 atgaaacact tattactcat actgctgaga aacctaaaga ggaaaaaatg atagtagaag
    14641 aaaaggctga taaagctttg gaaactaaaa atgtagttga aaggacagaa caaagtgaac
    14701 ctagttcaac tgaggctatt gcatctgaga agaaagaaga tgaagccgta actccaaaag
    14761 aggaaaaagt gtctgctaaa ccggaagaaa aagctccaag gatagaatca caagcttcaa
    14821 atcaagaaaa accgctcaag gaagatgcta aagctgtaac aaatgaagaa gtgaatcaaa
    14881 tgattgaaga caggaaagtg gattttaatc aaaattggta ttttaaactc aatgcaaatt
    14941 ctaaggaagc cattaaacct gatgtagacg tatctacgtg gaaaaaatta gatttaccgt
    15001 atgactggag tatctttaac gatttcgatc atgaatctcc tgcacaaaat gaaggtggac
    15061 agctcaacgg tggggaagct tggtatcgca agactttcaa actagatgaa aaagacctca
    15121 agaaaaatgt tcgccttact tttgatggcg tctacatgga ttctcaagtt tatgtcaatg
    15181 gtcagttagt ggggcattat ccaaatggtt ataaccagtt ctcatacgat atcaccaaat
    15241 accttcacaa agatggtcgt gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa
    15301 gtagccgttg gtattcagga agtggtatct atcgtgatgt gactttacaa gtgacagata
    15361 aggtgcatgt tgagaaaaat gggacaacta ttttaacacc aaaacttgaa gaacaacaac
    15421 atggcaaggt tgaaactcat gtgaccagca aaatcgtcaa tacggacgac aaagaccatg
    15481 aacttgtagc cgaatatcaa atcgttgaac gaggtggtca tgctgtaaca ggcttagttc
    15541 gtacagagag tcgtacctta aaagcacatg aatcaacaag cctagatgcg attttagaag
    15601 ttgaaagacc aaaactctgg accgttttaa atgacaaacc tgccttgtac gaattgatta
    15661 cgcgtgttta ccgtgacagt caattggttg atgctaagaa ggatttgttt ggttaccgtt
    15721 actatcactg gactccaaat gaaggtttct ctttgaatgg tgaacgtatt aaattccatg
    15781 gagtatcctt gcaccacgac catggggcgc ttggagcaga agaaaactat aaagcagaat
    15841 atcgccgtct caaacaaatg aaggagatgg gagttaactc catccgtaca acccacaacc
    15901 ctgctagtga gcaaaccttg caaatcgcag cagaactagg tttactcgtt caggaagagg
    15961 cttttgatac ttggtatggt ggcaagaaac cttatgacta tggacgtttc tttgaaaaag
    16021 atgccactca cccagaagct cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca
    16081 tggtcgaaag aggcaaaaac aaccctgcta tcttcatgtg gtcaattggt aatgaaatag
    16141 gtgaagctaa tggtgatgcc cactctttag taactgttaa acgtttggtc aaggttatca
    16201 aggatgttga taagactcgc tatgttacca tgggagcaga taaattccgt ttcggtaatg
    16261 gtagcggagg gcatgagaaa attgctgatg aactcgatgc tgttggattt aactattctg
    16321 aagataatta caaagccctt agagctaagc atccaaaatg gttgatttat ggatcagaaa
    16381 catcttcagc tacccgtaca cgtggaagtt actatcgccc tgaacgtgaa ttgaaacata
    16441 gcaatggacc tgagcgtaat tatgaacagt ctgactatgg gaatgatcgt gtgggttggg
    16501 ggaaaacagc aaccgcttca tggacttttg accgtgacaa cgctggctat gctggacagt
    16561 ttatctggac aggtacggac tatattggtg aacctacacc atggcacaac caaaatcaaa
    16621 ctcctgttaa gagctcttac tttggtatcg tagatacagc cggcattcca aaacatgact
    16681 tctatctcta ccaaagccaa tgggtttctg ttaagaagaa accgatggta caccttcttc
    16741 ctcactggaa ctgggaaaac aaagaattag catccaaagt agctgactca gaaggtaaga
    16801 ttccagttcg tgcttattcg aatgcttcta gtgtagaatt gttcttgaat ggaaaatctc
    16861 ttggtcttaa gactttcaat aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg
    16921 caaatgctaa tgaactttat cttgaatgga aagttgccta tcaaccaggt accttggaag
    16981 caattgctcg tgatgaatct ggcaaggaaa ttgctcgaga taagattacg actgctggta
    17041 agccagcggc agttcgtctt attaaggaag accatgcgat tgcagcagat ggaaaagact
    17101 tgacttacat ctactatgaa attgttgaca gccaggggaa tgtggttcca actgctaata
    17161 atctggttcg cttccaattg catggccaag gtcaactggt cggtgtagat aacggagaac
    17221 aagccagccg tgaacgctat aaggcgcaag cagatggttc ttggattcgt aaagcattta
    17281 atggtaaagg tgttgccatt gtcaaatcaa ctgaacaagc agggaaattc acactgacag
    17341 cccactctga tctcttgaaa tcgaaccaag tcactgtctt tactggtaag aaagaaggac
    17401 aagagaagac tgttttgggg acagaagtgc caaaagtaca gaccattatt ggagaggcac
    17461 ctgaaatgcc taccactgtt ccgtttgtat acagtgatgg tagccgtgca gaacgtcctg
    17521 taacctggtc ttcagtagat gtgagcaagc ctggtattgt aacggtgaaa ggtatggctg
    17581 acggacgaga agtagaagct cgtgtagaag tgattgctct taaatcagag ctatcagttg
    17641 tgaaacgtat tgctccaaat actgacttga attctgtaga caaatctgtt tcctatgttt
    17701 tgactgatgg aagtgtacaa gagtatgaag tagatagctg ggagattgcc gaagaagata
    17761 aagctaagtt agcaattcca ggttctcgta ttcaagcgac cggttattta gaaggtcaac
    17821 caattcatgc aacccttgtg gtagaagaag gcaatcctgc agcacctgta gtgccaactg
    17881 ttactgttgg aggtgaagca gtaacaggtc ttactagtcg acaaccaatg caatatcgta
    17941 ctctatctta tggtgcccaa ttgccagaag tcacagcaag tgctgaaaat gctgatgtga
    18001 cagttcttca agcaagcgca gcaaacggca tgcgtgcgag catctttatt cagcctaaag
    18061 atggtggccc tcttcaaacc tatgcaattc aattccttga agaagcgcca aaaattgctc
    18121 acttgagttt gcaagtggaa aaagctgaca gtctcaaaga agaccaaact gtcaaattgt
    18181 cggttcgagc tcactatcaa gatggaacgc aagctgtatt accagctgat aaagtaacct
    18241 tctctacaag tggtgaaggg gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagt
    18301 caggagcagt cactctgaac gctgaatatg agggagctaa aggccaagtt gaactcacta
    18361 tccaagccaa tactgagaag aagattgcgc aatctatccg tcctgtaaat gtagtcacag
    18421 atttgcatca aaaacctact cttccaacaa cagtaacggt tgagtatgac aaaggtttcc
    18481 ctaaagctca caaagtcact tggcaagcta ttccgaaaga aaaactagac tcctatcaaa
    18541 catttgaagt actaggtaaa gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg
    18601 tagaaggtat cgtttcagtt gaagaagtca gtgtgacaac tccaatcgca gaagcaccac
    18661 aattaccaga aagcgttcgg acatatgatt caaatggtca cgtttcatca gctaaggttg
    18721 catgggatgc gattcgtata gagcaatacg ctaaggaagg tgtctttaca gttaatggtc
    18781 gcttagaagg tactcaatta acaactaaac ttcatgttcg cgtatctgct caaactgagc
    18841 aaggtgcaaa catttctgac caatggaccg gttcagaatt gccacttgcc tttgcttcag
    18901 attcaaatcc aagcgaccca gtttcaaatg ttaatgacaa gctcatttcc tacaataacc
    18961 aaccagccaa tcgttggaca aactggaatc gtagtaatcc agaagcttca gtcggtgttc
    19021 tgtttggaga ttcaggtatc ttgagcaaac gctccgttga taatctaagt gtcggattcc
    19081 acgaagacca tggagttggt gcaccgaagt cttatgtgat tgagtattat gttggtaaga
    19141 ctgtcccaac agctcctaaa aaccctagtt ttgttggtaa tgaggaccat gtctttaatg
    19201 attctgccaa ctggaaacca gttactaatc taaaagcccc tgctcaactc aaggctggag
    19261 aaatgaacca ctttagcttt gataaagttg aaacctatgc tgttcgtatt cgcatggtta
    19321 aagcagataa caagcgtgga acgtctatca cagaggtaca aatctttgcg aaacaagttg
    19381 cggcagccaa acaaggacaa acaagaatcc aagttgacgg caaagactta gcaaacttca
    19441 accctgattt gacagactac taccttgagt ctgtagatgg aaaagttacg gcagtcacag
    19501 caagtgttag caacaatggc ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccgg
    19561 ttcgtgtcat cgcgaaagct gaaaatggcg acatcttagg agaataccgt ctgtacttca
    19621 ctaaggataa gaacttactt tctcataaac cagttgctgc ggttaaacaa gctcgcttgc
    19681 tacaagtagg tcaagcactt gaattgccga ctaaggttcc agtttacttc acaggtaaag
    19741 acggctacga aacaaaagat ttgtcagttg aatgggaaga agttccagca gaaaatctga
    19801 caaaagcagg tcaatttacc gttcgaggcc atgtccttgg tagtgatctt gttgctgagg
    19861 tcactgtacg agtgacagac aaactaggcg aagctctttc agataaccct aactatgatg
    19921 aaaacagtaa ccaggccttt gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc
    19981 gcgttgacta tctcaatgac ggagattatt cagaaaatcg tcgttggaca aactggtctg
    20041 caagaccgtc taccaatcca gaagtatcag caggcgtaat cttccgtgaa aatggtaaga
    20101 ttgtcgaacg gactgttgcg caagccaaac ttcatttctt tgcagatagt ggtacagatg
    20161 caccatctaa acttgttttg gaacgttatg tcggcccagg ctttgaagta cctacctact
    20221 attcaaacta ccaagcctac gaatctggac atccatttaa caatccagaa aattgggaag
    20281 ctgtgcctta tcgtgcggat aaagacatcg cagctggtga tgaaatcaac gtaacattta
    20341 aagctgtcaa agccaaagcc atgagatggc gtatggagcg taaagctgac aagagcggtg
    20401 ttgcgatgat tgagatgacc ttccttgcac caagtgaatt gcctcaagaa agcactcaat
    20461 caaagattct tgtagatgga aaagaacttg ctgatttcgc tgaaaatcgt caagactatc
    20521 aaattaccta taaaggtcaa cggccaaaag tctcagttga agaaaacaat caagtagctt
    20581 caactgtggt agatagcgga gacgatagcc ttccagtact tgttcgcctc gtttcagaaa
    20641 gtggaaaaca agtcaaggaa taccgtatcc acttgactaa ggaaaaacca gtttctgaga
    20701 agactgttgc tactgtacaa gaagatcttc caaaactcga atttgttgaa aaagatttgg
    20761 cctacaagac agttgagaaa aaagattcaa cactgtatct aggtgaaact cgtgtagaac
    20821 aagaaggaaa agttggaaaa gaacgtatct ttacagcgat taatcctgat ggaagtaagg
    20881 aagaaaaact ccgtgaagtg gtagaagctc cgacagaccg catcgtcttg gttggaacca
    20941 aaccagtagc tcaagaagct aaaaaaccac aagtgtcaga aaaagcagat acaaaaccaa
    21001 ttgattcaag tgaagctagt caaactaata aagcccagtt accaaataca ggtagtgcgg
    21061 caagtcaagc agcagtagca gcaggtttag ctcttctagg tttgagtgca ggattagtag
    21121 ttactaaagg taaaaaagaa gactagaaat tttgatacct tctttatcat taaagaccaa
    21181 agaaaaactc ttgtcctaaa tagaagataa agagtctggg acaaaatagt tctcaaccac
    21241 aaaaagctag agatttccaa ttgcggaact ctagcttttt aattttgagt cgttctctta
    21301 ttgtatagta gattgaaact agaatagtac acttctactt ctaaaacatt gttagaaatc
    21361 gatttgactg tccttatcga tttgtcctgt tcttatttca tttcactata ttttaggagg
    21421 ttattggcca taagtaccaa tcccatgtca attctcactt gacgcttccc tctcagatta
    21481 catctcttgt aacccaaaca agcctttatc tgcccaaaga caggttccac atcaatcttg
    21541 cgttgagcga aaatctgtct accttgggga gataaaagcg cctgacattc tttagctttc
    21601 aagttttgat agcgttcgtt catatacagt cccttttgag ggactgattc aggttcatca
    21661 gcgtagtaaa ccttgatttc ctgttgaaag tctgtctgtg ttttctggta cttgatatgg
    21721 tgaaaacgat agcaccagcc atcaggatgt gtgtagctat cctccttgtc attatagtgc
    21781 caattcgcta agtttttagc tgactgttta taccctctct tttgtttctt atcaaacatg
    21841 gcatatttaa tcagaagggg agtgatttct tcttgaaaat agacctgtat ctgttcttga
    21901 agtttggcgg agaatttctc tgtcgttttc ttccacacaa aactatactt gttggcattg
    21961 gcttcaatct tagttccgtc aataaacaaa caatctaagg tcactaactc ttccattttt
    22021 caatttttcg accagagaaa atcccttgtg aataggcaaa tagaagagta gatacaagca
    22081 ttttagggtg ataagacggg cgatcaaagg catgatagga ggtgtagaag tgacgttcct
    22141 ccaaggtatt caccactttt tcaatagtaa agacgagatg gtcttgtggt aagaaggaac
    22201 tgatttctag tggtaaagtt gtttgatttg tgttatagtg aatatgcatg ggatagcctt
    22261 tttaaatggt ttattaagca attctatttt accaagacta tcgtaaccat gcaaaaaaag
    22321 caacggcaaa tccgttgctt tttttggaga taagagacta ttgtcccagc ctcttttctt
    22381 tgtataaaat tgtatagtgt tattgtctat actattttgt agagaaagca aaaatcccta
    22441 gaaaatgctt agggattcga ctatttcatt aagaacaatt caacaatcat ttctatatac
    22501 atgataaggg ttaataagaa tcctgcacgc cagaagaatt tgataaattt aggatagtaa
    22561 aagctgcgtt ttttcaaaag gaagaaaaag acgagaataa tggctaggaa cgagagggct
    22621 agccccagtc tagggaggaa attatgggta aaggttttag ctgtaatcaa gtaatactca
    22681 aataccaaga ctggaaaagc caaatccgca aagtttcgtc ctagtttttt taatctaaaa
    22741 agtttggtta ggataatgca gacgactaag gtcagtatca ataataaaat agatgctaat
    22801 ttcattaaaa tcatacccat attgtatcat aaaaaaaggc taatggaaac gagaaacaga
    22861 ggaatttata ggaaagtcag gcttttgaga ttgtgggtga tttttgttat aatgaaagtt
    22921 ataaaatctt ataatacctt gaatgattat tatcgaaaac tctttggaga aaagactttt
    22981 aaagtcccta ttgatgcggg atttgactgt cccaatcgtg atggaactgt ggctcatgga
    23041 ggctgtactt tttgtacggt ttccggttct ggagatgcca ttgtggcacc agatgcgcct
    23101 atccgtgagc aattttataa ggaaattgac tttattcatc gtaagtggcc agatgtttag
    23161 aagtatctgg tttattttca aaattttacc aacacccatg aaaaggtgga agttattcga
    23221 gagcgttatg aacaggctat caatgagcca ggtgtggtag gaatcaatat tggaacgcgc
    23281 ccagactgtt taccagacga aaccatcgaa tatttggctg agttatcgga gtgcatgcat
    23341 gtgacggttg aattgggctt gcaaactact tatgaagcaa cctctgacct gattaaccgt
    23401 gcgcattctt atgaattgta ggtggaaacg gtcaagcgtt tgagaaagta tccaaaaatt
    23461 gagattgttt cccatttgat caatggtttg cctggtgaaa cccatgagat gatggttgaa
    23521 aatgtccgcc gttgtgtcac ggataacgat attcaaggga ttaaactgca tttgctccat
    23581 cttatgacaa atactcgtat gcaacgagat taccatgagg ggcgtttaca attgatgagt
    23641 caggacgaat atgtcagggt catctgtgac caactggaaa ttattcccaa acatatcgtc
    23701 atccatcgaa ttacaggaga tgcgcctagg gatatgctgc ttgggcctat gtggagcctc
    23761 aataaatggg aagctctcaa cagcattgag atggagatgc gacgtcgtgg aagtgttcaa
    23821 ggatgcaagg ctgtaaaaca ggagtttgaa aatgaaaaga ccacttgaga tggcacatga
    23881 ttttttggct gaggtcgtga caaaagagga tgtcgtagtg gatgcgacta tgggaaatgg
    23941 tcatgacacg ctttttttag ccaagctagc caagcaagtc tatgcctttg atattcagaa
    24001 gcaagccttg gaaaagaccc aagagcgttt gcatcaggct gacttgacaa atgcccagtt
    24061 aatcttgcaa ggccatgaga cactggacca gtttgtgata aaagctaagg cagggatttt
    24121 taatctgggc tatttgccgt cagctgataa gtctgtcatc acccgaccgc agacaacgat
    24181 tgaggcatta gaaaagctat gtggcttact tgtcaaaggt ggacgaattg ctattatgat
    24241 ttactatggt catgaaggag gcgatctcga gagagatgct gtcttggatt ttgtgatcca
    24301 gttgaaccaa caagagtaca cagctgccat ttaccgaact ttaaaccaag tcaacaaccc
    24361 gccgttttta gtgatgattg aaaaattaga gagatacaga catggataaa caatacctac
    24421 acgaaaagct ggatgccatg cgccagaatt ttgttgaatc aacccaccac gaacgatcgg
    24481 tgggcgtgct agaccaagcg catatgagca aaaaaatgct taaaatcaag aaaaaattag
    24541 ttgctcttga aatggaacgg tgccagagaa aaattgagca caaagactgt tccaagattg
    24601 accaaaaaat caaagagcag aaggagatat ttgaatcctg ttgtaaaaaa gattaaggag
    24661 gacgtgcgtg gaattactga tttacctcat cctattttta ctggttttga ttgtctcaag
    24721 tacaaccaat aagctcctgc cctttttgcc tctccctttg gtgcagattc ttttgggaat
    24781 tgtgattggt ctctttttac ccaatactga ctttcacctt aatacggagt tgtttttggc
    24841 actggttatc ggacccttgc ttttccgaga ggctgaagaa gcagatgtta cggctatttt
    24901 aaaacactgg cgaatcattg tttatctcat atttccagtg atttttatct cgaccttgag
    24961 tttgggtggc ttggcccatc ttctttggtt cagccttccc ttggcagctt gcttggctgt
    25021 tggggcagcc cttggtccta cggacttggt ggcctttgcc tctctttcgg agcgttttag
    25081 ctttcctaag cgcgtgtcca atattcttaa gggcgaagga ctcttgaatg atgcttctgg
    25141 tttggtggct tttcaggtag ctttgacagc ttggacaact ggagcttttt ctctggggca
    25201 agctagcagt tcgctcatct tttcaatcct aggcggtttt ttaattggat ttttaacggc
    25261 catgaccaac cgcttcctcc ataccttctt gctaagtgtg cgcgcaacgg atattgccag
    25321 tgaactttta ttagaattga gtttgcctct agtgaccttc tttctggcag aagaagttca
    25381 tgtttcaggt attattgccg tcgtagttgc tggaatttta aaggcaagtc gcttcaagaa
    25441 aatcacgctc ctcgaagccc aagtggatac ggtgaccgag acggtctggc atacagtgac
    25501 ctttatgctc aacggttctg tctttgtgat tttagggatg gagttggaaa tgatagcaga
    25561 acctatcttg accaatccaa tctataatcc tctactttta ttgctatctc tcatcgccct
    25621 tacctttgtc ctctttgtca ttcgttttat tatgatctat ggctattatg cctatagaaa
    25681 ccgacgcctc aagaaaaagc taaataagta tatgaaggac atgtttctct tgaccttttc
    25741 aggtgttaag ggaacggtgt cgattgctac gattctcttg ataccaagta atctagaaca
    25801 ggagtatcct cttttgcttt tccttgttgc aggtgtgacg cttgtcagct ttttaacagg
    25861 tctcttggtc ttgcctcatc tttctgatga agaggaagaa agcaaggatt atctcatgca
    25921 tatcgccatt ttgaatgaag taacgctaga gttggaaaaa gagttggaag acaccagaaa
    25981 taaacttccc ctctatgcgg ctattgacaa ttatcatgga cgtattgaaa atctcatttt
    26041 aagccaagaa aaccaggatg atcaagaaga ttgggctgct ttgaaactct tgattcttag
    26101 tattgaaagt gatggtttgg aacaggccta tgaagagggg aacattagca atcgtgctta
    26161 ccgagtttac caacgttatc tgaaaaatat agaacaagga atcaatcgta aacttgcctc
    26221 aagactgacc tattatttcc ttgtttcttt gcggatttta cgttttctcc ttcatgaagt
    26281 ttttactctc ggaaagacct tccgtagctg gaagaacaag gagcaaagcc gtctccgtgc
    26341 tcttgattat gaccaaattg cagagctcta tcttgccaat acggagatga ttattgaaag
    26401 tttggaaaac ctgaagggag tctacagacg ctctttgatt agttttatgc aggagtctcg
    26461 tcttcgagaa acaactatta tcagcagtgg tgcctttgtc gaacgggtta tcaatcgtgt
    26521 caaacccaac aatatcaatg aaatgctgag aggctattat ctggagcgca agttgatttt
    26581 cgaatacgaa gaaaaacgat taattacaac taagtatgcc aagaaattac gacaaaatgt
    26641 aaataactta gagaactatt ccttgaagga agctgccaat accctgccgt atgatatggt
    26701 ggaattggta agaagaaatt agttaatact cttcgaaaat ctcttcaaac cacgtcagcg
    26761 tcgccttgcc gtatgtatgt gactgacttc gtcagtctta tctacaacct caaaacagtg
    26821 ttttgagcag cttgcggcta gctttctagt ttgctctttg attttcattg agtataagat
    26881 tataaatgaa ggagtatgac atgaaaaagt ggtggaaaga gctgatagac aagcctttat
    26941 taaaagcttt tttgcattat tatcaagcat cagatagtga gttgaccagt gtcgcagtag
    27001 cctactattg gttgatttcg attttccccc tgcttttggt ggtggtcaat atcctcccct
    27061 attttcagat tcctgtggga gaatttctgg gctttatgaa agacgtcctg cccccaagcc
    27121 tctatgaagg tgtggaaaaa atagccagag aagtcttgac gcaaccttca acaggtttat
    27181 tgagtttttc tgttttatcg gcgttatgga gtttttcaaa atctatgaat ttcttgcaaa
    27241 aagcttttaa caaggcttat ggcgtcgaaa agagtcgtgg acttatttcc catcagatgc
    27301 taagtctcct agtcagtttt ggcttgcagc tcctctttgc gtttgccttg tttttgattt
    27361 tatttggtca gatgattttg gctttacttg ctcattattg gacaaaagat ggcattatct
    27421 atcaggcttt acaagggttg gcaggtcctc tgatttacgc cctcctcttt gctatcttgg
    27481 tcatgcttta ttattttctt cccaatctat ctaacaggaa aattagctat accctaccag
    27541 gcagtgcctt tgttctctta gtgattttag gtttactaac tctgttctct agttatctca
    27601 attactatgt ccatcatttg gtggatgtcc gaattttagg ttccgttctt cttgttgtta
    27661 tgatgttttg gtttatcttg attgctaaaa ttgttatcct aggcgcggtt atcaatgcca
    27721 gtatgcagag tttgaaagat ccggtcttta aaaaagacta actatttatc cattacaaaa
    27781 gcgcatagta tcaagacttt atagaacctt gatactatgc gcttttgtgc tttgacagtt
    27841 ttttgtatag tttttgtcca agatttctaa atcatctgat taaattccta ttttccccta
    27901 tcattgtccc tgttttttcg aaaatggaag gagtataata aatctatcaa taaaatgata
    27961 ggaggaactt tatgggtcat attttctttt ttctaagtgt ctttttggca gggattctat
    28021 ccttcttttc tccttgtatc ttacctttgt taccggtcta tacaggagtg ttactagatg
    28081 ataaggatgg tgctcaggct tctagcggca aattttcaat ctcagttact agtttattac
    28141 gaactctggt ctttatagca ggaatttcct ttatatttat tttgttgggc tatggagctg
    28201 gttttttagg cgatttgctt tatgcttctt ggttccaata tcttactggg gcaattatta
    28261 tccttcttgg tttgcaccaa atggagattc tacactttaa ggggctttat aaggaaaaga
    28321 ggctacaact gcaaggacag gggcaaaatg gtaagggcta tagtcaggca tttttattgg
    28381 gcttgacctt tagttttgct tggacgcctt gcgtggggcc ggttctgggg tctgttttgg
    28441 ccttggcggc ttcaggtggt tcaggagctt ggcagggagc tggtctcatg ttggtgtata
    28501 cgctgggctt ggcgctacca ttcttgcttc tagctctgac ctctagttat gttttgaaac
    28561 atttccgaaa acttcatccc tatctcggaa tcctcaaaaa agtgggtggt tttctcatta
    28621 ttgtgatggg attcttggtt ctgtttggaa atgcttcaat tttaagtcaa ttatttgaat
    28681 aaaatggaaa ggaatatcaa tatgaaaaaa tggcaaacat gtgttcttgg agcaggttcg
    28741 ctcctttgtt tgacggcttg ttcaggcaag tccgtgacta gtgaacacca aacgaaagat
    28801 gaaatgaaga cggagcagac agctagtaaa acaagcgcag ctaaagggaa agaggtggct
    28861 gattttgaat tgatgggagt agatggcaag acctaccgtt tatctgatta caagggcaag
    28921 aaagtctatc tcaaattctg ggcttcttgg tgttccatct gtctggctag tcttccagat
    28981 acggatgaga ttgctaaaga agctggtgat gactatgtgg tcttgacagt agtgtcacca
    29041 ggacataagg gagagcaatc tgaagcggac tttaagaatt ggtataaggg attggattat
    29101 aaaaatctcc cagtcctagt tgacccatca ggcaaacttt tggaaactta tggtgtccgt
    29161 tcttacccaa cccaagcctt tatagacaaa gaaggcaagc tggtcaaaac acatccagga
    29221 ttcatggaaa aagatgcaat tttgcaaact ttgaaggaat tagcctagga ggcgtcttat
    29281 gaatgataag ttaaaaatct tcttgttgct aggagtattt tttctagcca taaccggttt
    29341 ctatgttcta ttgatacgaa atgcagggca gacagatgcc tcgcaaattg aaaaggcggc
    29401 agttagccaa ggaggaaaag cagtgaaaaa aacagaaatt agtaaagacg cagacttgca
    29461 cgaaatttat ctagctggag gttgtttctg gggagtggag gaatatttct cacgtgttcc
    29521 cggggtgacg gatgccgttt caggctatgc aaatggtaga ggagaaacaa ccaagtacga
    29581 attgattaac caaacaggtc atgcagaaac cgtccatgtc acctatgatg ccaagcaaat
    29641 ttctctcaag gaaatcctgc ttcactattt ccgcattatc aatccaacca gcaaaaataa
    29701 acaaggaaat gatgtgggga cccagtaccg tactggtgtt tattacacag atgacaagga
    29761 tttggaagtg attaaccaag tctttgatga ggtggctaag aaatacgatc aacctctagc
    29821 agttgaaaag gaaaacttga agaattttgt ggtggctgag gattaccatc aagactatct
    29881 caagaaaaat ccaaatggct actgccatat caatgttaat caggcggcct atcctgtcat
    29941 tgatgccagc aaatatccaa aaccaagtga tgaggaattg aaaaagaccc tgtcacctga
    30001 ggagtatgca gttacccagg aaaatcaaac agaacgagct ttctcaaacc gttactggga
    30061 taaatttgaa tccggtatct atgtggatat agcaactggg gaacctctct tttcatcaaa
    30121 agacaaattt gagtctggtt gtggctggcc tagttttacc caacccatca gtccagatgt
    30181 tgtcacctac aaggaagata agtcctacaa tatgacgcgt atggaagtgc ggagccgagt
    30241 aggagattct caccttgggc atgtctttac ggatggtcca caggacaagg gcggcttacg
    30301 ttactgtatc aatagcctct ctatccgctt tattcccaaa gaccaaatgg aagaaaaagg
    30361 ctacgcttat ttactagatt atgttgatta atactcttcg aaaatctctt caaaccacgt
    30421 cagcgtcgcc ttaccgtatg tagggttact gacttcgtca gttttatcta caacctcaaa
    30481 gctatacttt gagctgactt cgtcagtttt atttacaacc tcaaagcggt actttgagaa
    30541 acctgtggct atcttcctag tttacttttt gatttttatt gagtataaga ggtctttcct
    30601 aagcagttag aggagaattt tgctatactg atactagtaa gtggtaaagg agcagatcat
    30661 gacctacaca atcttaatcg tagaagatga atatctggta agacaaggtt tgactaaact
    30721 ggtcaatgta gcagcctacg atatggaaat catcggtcag gctgaaaatg gaaggcaggc
    30781 ttgggaattg atccaaaagc aggtgccaga tatcatttta accgatatca acatgcctca
    30841 tctaaatggc atccagttgg ccagtctggt acgagaaacc tatcctcagg ttcatttggt
    30901 ctttttaaca ggttacgatg attttgatta tgccttgtct gctgtcaaac taggtgtgga
    30961 cgactacctg ctcaaaccct tttctcgtca ggatattgag gaaatgttgg ggaaaatcaa
    31021 acaaaaacta gacaaggaag agaaagaaga gcagttacaa gatttattga ctaataggtt
    31081 tgaaggaaac atggcccaga aaatccagtc tcatctggct gatagccaat ttagtttaaa
    31141 gtctttagcc agtgacttag gttttagtcc gacctatctg agttccttga ttaagaaaga
    31201 gttgggcttg ccttttcagg attatctggt gagagaacgt gttaaacaag ccaagctctt
    31261 gcttttaact acagatctga agatttatga gatcgcagag aaggttggtt ttgaagatat
    31321 gaactatttt acccaacgtt ttaagcagat tgcaggtgtg acacctcgtc agtttaagaa
    31381 gggagaagac cgatgaagcg ttcttctctt ttagttagaa tggttatttc catctttctg
    31441 gtctttctca ttctcctagc tctggttgga actttctact atcaatcaag ttcttcagcc
    31501 attgaggcca ccattgaggg caacagccaa acgaccatca gccagactag ccactttatt
    31561 cagtcttata tcaaaaaact agaaaccacc tcgactggtt tgacccagca gacggatgtt
    31621 ctggcctatg ctgagaatcc cagtcaagac aaggtcgagg gaatccgaga tttgtttttg
    31681 accatcttga agtcagataa ggacttgaaa actgttgtgc tggtgaccaa atctggtcag
    31741 gtcatttcta cagatgacag tgtgcagatg aaaacttcct ctgatatgat ggctgaggat
    31801 tggtaccaaa aggctattca tcagggagct atgcctgttt tgactccagc tcgtaaatca
    31861 gatagtcagt gggtcatttc tgtcactcaa gaacttgttg atgcaaaggg agccaatctt
    31921 ggtgtgcttc gtttggatat ttcttatgaa actctggaag cctatctcaa tcaactccag
    31981 ttggggcagc agggctttgc cttcattatc aatgaaaacc atgaatttgt ctaccatcct
    32041 caacacacag tttatagttc gtctagcaaa atggaggcta tgaaacccta catcgagaca
    32101 ggtcagggtt atactcctgg tcacaaatcc tacgtcagtc aagagaagat tgcaggaact
    32161 gattggacgg tacttggcgt gtcatcattg gaaaagttag accaggttcg gagtcagctc
    32221 ttgtggacct tgcttggggc cagtgtcaca tctcttcttg tctgtctctg cttagtgtgg
    32281 ttcagtctta aacgctggat tgctcctttg aaggatttga gagaaaccat gttggaaatt
    32341 gcttctggtg ctcaaaatct tcgtgccaag gaagttggtg cctatgaact gagagaagta
    32401 actcgccaat ttaatgccat gttggatcag attgatcagt tgatggtagc tattcgtagc
    32461 caggaagaaa cgacccgtca gtaccaactt caagcccttt cgagccagat taatccacat
    32521 ttcctctata acactttgga caccatcatc tggatggctg aatttcatga tagtcagcga
    32581 gtggtgcagg tgaccaagtc cttggcaacc tatttccgct tggcgctcaa tcaaggtaag
    32641 gacttgattt gtctctctga cgaaatcaat catgtccgcc agtatctctt tatccagaaa
    32701 caacgctatg gagataagct ggaatacgaa attaatgaaa atgttgcctt tgataattta
    32761 gtcttaccca agctggtcct acaacccctt gtagaaaatg ctctttacca tggcattaag
    32821 gaaaaggaag gtcagggcca tattaaactt tctgtccaga aacaggattc gggattggtc
    32881 atccgtattg aggatgatgg cgttggcttc caagatgctg gtgatagtag tcaaagtcaa
    32941 ctcaaacgtg ggggagttgg tcttcaaaat gtcgatcaac ggctcaaact tcattttgga
    33001 gccaattacc agatgaagat tgattctaga ccccaaaaag gaacgaaagt tgaaatatat
    33061 ataaatagaa tagaaactag ctaactccca gtcaattctg ggagttttat gcgtaattgg
    33121 gcagacttta taggttgtct atcttgctaa aaacaagaaa aaacggtatg atagaagagt
    33181 gacaacagag gtaacagaga tgaacgagac acagattcaa agagaaacac gtcaggtagt
    33241 ggaagatgtt ttagaaaaga ccaatttgaa gcagggggtc ctttttgttt taggcctatc
    33301 ttctagtgag gtgctaggtg gtcagattgg gaaagaatcc agtcaagaga ttggtgagct
    33361 gatagtggag actatcttgg gtattctagg tagtagaggt atccatttag cagttcaagg
    33421 ttgtgagcat gtcaatcggg ctctcgttgt tgaacgtcag gtggcagagc agtttgatct
    33481 ggaaattgtc agtgtccatc ctactcttca tgcaggaggt tcggggcagt tggcagcctt
    33541 taagtttatg caggatccag ttgaggttga atttatcaag gctcatgctg gattggatat
    33601 cggagacact gcaattggca tgcatgtcaa gcatgttcag gttccgattc gccctatttt
    33661 gagagagatt ggtcatgccc atgtaacggc actggctagt cgtccaaaat taatcggagg
    33721 tgcgcgtgcg cactatccgc aagatgctat tagaaagtct tgagaatgaa taaaggagat
    33781 gaaagtgttt aaaaaagacc gtttttcaat tcgtaagatt aagggagttg taggctctgt
    33841 atttcttgga agccttttga tggctccttc tgtagtggac gcagctacct atcactatgt
    33901 aaataaagag attatttcac aagaagctaa agatttaatt cagacaggaa agcctgacag
    33961 gaatgaagtt gtatatggtt tggtgtatca aaaagatcag ttgcctcaaa cagggacaga
    34021 agcatctgtt ttgacagctt ttggtttgct gactgttggg agcttgcttt taatctacaa
    34081 gagaaagaaa attgctagcg tctttctagt tggagctatg ggattggtag ttcttcctag
    34141 tgcaggggct gtagacccag ttgcgaccct agcgctggct agtcgagagg gtgttgttga
    34201 aatggatggc tatcgctatg ttggttatct atcaggtgac atcctcaaaa cgcttggctt
    34261 ggacactgtt ttagaagaaa cctcagcaaa acctggagag gtgactgtag tcgaagttga
    34321 gactcctcaa tcaacaacaa atcaggagca agctaggaca gaaaaccaag tagtagagac
    34381 agaggaagct ccaaaagaag aagcacctag aacagaagaa agtccaaagg aagaaccaaa
    34441 atcggaggta aaacctactg acgacaccct tcctaaagta gaagagggga aagaagattc
    34501 agcagaacca gctccagttg aagaagtagg tggagaagtt gagtcaaaac cagaggaaaa
    34561 agtagcagtt aagccagaaa gtcaaccatc agacaaacca gctgaggaat caaaagttga
    34621 accaccagta gaacaagcaa aagtcccaga acaacccgtg caacctacac aagctgagca
    34681 accaagtaca ccaaaagaat catcacaaca agaaaatcct aaagaagata ggggagcgga
    34741 agagacaccg aaacaagaag atgaacagcc agcagaagcc ccagaaatca aggttgaaga
    34801 accagtagaa tcaaaagagg agactaaaac agctaagggg acgcaagaag aaggcaaaga
    34861 aggtcaagca ccagtacaag aagtaaaccc agaatataaa gtaacaacag gtacagttga
    34921 gaagtctacc gaaagtgaat tagatttcac aacagaagta gttccggatg acacaaaata
    34981 tgtagatgaa gaagttgttg aacgtcaagg gtctaaagga gttcaagtta cgaaaacaac
    35041 ttacgaaaca gtggaagttg tagagacaga caaagtcctt tctacaacta cagaagtgaa
    35101 aactcctgtt gttcctaaag tcgttaaaaa aggaacaaaa ccagttgaag gaacagcagt
    35161 tgaaacaaga gaagaagtca ttccttttgc tacaaaagaa caagaagatg gcactttaaa
    35221 acgcggaaca agacaagtag ctcaagaagg tgtaaacggt aagaaacaaa ttactgaaac
    35281 ctataaaaca attcgcgcag aaaaaacaaa cgaagctcca acagtagaag aaacagttct
    35341 ccaagcacct caagatgaga ttatcaaaaa aggcacaaaa ggtttagaaa aaccaacctt
    35401 agaatgggtt aaaacagata aagatgtctt gaagaagagt gcgacagcca gttatacatt
    35461 gaataaacca gatggggtag aaatcaaatc catcaaagta gctctaaaag ataatactgg
    35521 aacagttatt aaagaagtaa cggtagaaga aaataactta aacgttactt tagacaactt
    35581 gaaatattat caaggttata cactatccac aaccatggtc tataatcgag gcgaaggcga
    35641 agaaactgaa acgttagaag ataaagaagt tcagttagac cttaaaaaag ttgaaatcaa
    35701 aaacatcaaa gaaactagct tgatgagtgt ggatgatgct ggtgttgaaa cagataagag
    35761 cttacttact gaaaaaccga cagacgttgc tccactttac ctacgagtga caactcatga
    35821 taacaaagta acaagacttg ctgttgataa gattgaagaa gtagaagaag acggaaaaac
    35881 tttatacaaa gttactgcca aagcaccaga cttagttcaa cgtaatgctg ataacacact
    35941 tagcgaagag tatgttcatt actttgaaaa acaacttcca aaaattggaa atgtgtatta
    36001 caacttcaac gagttgatta cagatatgca aaaaacaccg aatggcgagt ttaaacttgg
    36061 tgcagacttg aatgctgtca atgttccaac accaaataaa tcttatgtga ctgctaaatt
    36121 tactggtaag ttgtatagtg aaggtgataa acactatact attcacaact tagcacgtcc
    36181 attgtttgcg caagctgaaa acgctcatat tcatgacatc aacctcggta atgtaaatat
    36241 taatatgccg tgggcgaaca aaacagcacc tcttggtgaa atgttcaaga agtcaactat
    36301 tgaaaacgtc aaagtaacag gtaatgttgt cggtaacaat gacgttacag gtatggtcaa
    36361 caaactggac gaatctgata tgcgtaacgt agctttcatt ggaaatatta caagtgtagg
    36421 tagcgctgga tggtggtctg gtggacttgt cagtgaaagc tggagaagta acacagataa
    36481 ttcttatatt gataccacca tcaaaggtaa taaagctaag gtaggtggat taattgctaa
    36541 gttaaatcac ggtgctgacc cacgagatgt tggtgcgaga ggtcgtttga agaactctgt
    36601 cgcaaaaggt actattgatg tgagagaccc acaagaaact ggtggattgc tgcattctaa
    36661 ctggtcatgg ggtcttgcag aaaacaatat taccatgatg aaagtgaaga atggaggaga
    36721 aattttatat ggttctcgtg atgcagaaga tgatgattac ttcggagcga attgggtgcg
    36781 taataataat gcgttcgtca atggaatcag tgaagggaaa caatcctatt ctcgttctag
    36841 tcgctggaaa gggatttctg aagatgaagc taaaactcgt attgccaaaa tgggaattac
    36901 agctcatgaa tacgaaatta cacaacattt gactgataaa ttgaaccgtg cagcatttaa
    36961 agaagacaca tataaaacaa ctcaagatta caaaactgaa agagaattag cgtatcgtaa
    37021 tattgaaaag cttcaaccat tctacaataa agaatggatt atcaaccaag gtaacaaatt
    37081 aacagacggt tcaaacttaa tgattaaaga ggtattgtcc gttataggta tgaagaacgg
    37141 tcagttcgtg accgatttgt ctgatattga taagattatg attcactacg ctgatggtac
    37201 gaaagaagaa aaaactgtca cacgtaaagc tgactcaaaa gtgcaacaaa ttcgtgaata
    37261 tagtgttgaa ggtcttggtg atgttgtgta cacaccaaat atggtcgaaa aagatagagc
    37321 gcaattaatt actgatatta aggcgaaatt ggatagcgtc caattgattt caccagaagt
    37381 gcgcaatttg atggataaac gtggcaaagc gcatgaaaac acggatgaac gtcgtaatgg
    37441 ctacattcga aacctattcc ttgaagaaag tttggatgaa gtgaaaggaa accttgataa
    37501 gcttgtgaaa gctcttgttg aaaatgaaga ccatcaattg aatggtgatg aagcggcaat
    37561 gaaagctctt gtcaagaaag ttgaagacaa caaagcgaaa atcatgttag gtcttgctta
    37621 tctcaatcgc tactatggat tcaaatatga cgaaaagtct atgaaggata ttatgatgtt
    37681 caaaccggac ttctatggta agaatgttag tgtcttggac ttcttgatta gagttggttc
    37741 aagagaacac aatattaaag gtaacagaac gttagaagct tatcgtgaag taattggtgg
    37801 aacgattggt atcggtgagt taaacggttt cttaaactat aatatgcgtt tattcacaga
    37861 agaaactgac atcaatactt ggtacaaaaa agctgtatcg cataccaact atattgttga
    37921 aaaacaatcc tcaaaccctg cgtttgccaa caagaaatat cgcctttatg aaaacttgaa
    37981 caatggtgaa catggtaaat atattttacc acttctcact acgaagaaag ctcatatgtt
    38041 cttgatttca acctataata cattagcgtt tagtgcgttt gagaaatatg gtaagaatac
    38101 agaagctgaa cgtgaagcgt ttaagaaaga aatcgattta cgtgctcaag agcaaattaa
    38161 ttacttagac ttctggtcaa gacttgcagc tgataatgta cgtgacagat tgttaaaatc
    38221 tgaaaatatg gttccgtctg caatttggga taaccaagaa gttccaggtc atggatgggc
    38281 tgatagaatg ggtcataata agaatggtga ctatgctccg gttcgtgagt tctatggacc
    38341 tacaggtaaa tggcatggat acaatggtac gggtgcatat gcttatatct ttactaatcc
    38401 acaaaactca gaagctgtat attatatcat atctagtatg atcagtgatt tcggtacttc
    38461 tgcattcact catgaaacta cacacattaa tgaccgtatg gcgtatctag gtggatggcg
    38521 tcaccgtgaa ggtactgacg tagaagcatt tgcccaaggt atgttacaat caccggctgt
    38581 ctcaagtccg aacggcgact acggtgcttt aggtcttaac atggcttaca aacgtgaaaa
    38641 cgatggtaac caatggtaca actatgattc aaataaatta gatagtcgtg cgaagattga
    38701 ccattacatg aagaattaca acgaagcgct catgatgctt gaccacttag aagctgatgc
    38761 cgttatcgcg aagaataacg gagataacaa caagtggttc aagaagatgg ataagaaatg
    38821 gcgtgagaac gctaatcgaa atggattagt gggacaacca caccaatggg atttacttcg
    38881 tgacctaaat gaagaagaga ataagaagaa attgacaagc attgatgacc ttgtagatgg
    38941 aaattatgta acgaagcata atatgccggg taataaacac tatcgtgctg aagggtttga
    39001 tacagcgtat caaactgtaa acatgatggc tggtatttac ggtggtaata ctagtaagag
    39061 tgctgttggt tctatctcgt tcaaacataa caccttccgt atgtggggtt acttcggtta
    39121 tcttgatgga tttgtaggtt atgcatctaa caaatataaa gacgcggcta acaaagaaaa
    39181 taaaggctta cttggcgacg actttattat caagaaagtg tctgacggta aatttgacag
    39241 cctagaagct tggaagaaag aatggtttaa agaagttaaa gctaaaggtg aaaaaggatt
    39301 tgttgctatt gaaattgatg gtaaaacaat cactaactat gctgaacttc gtgaattgtt
    39361 cgacaaagct gttgaagctg acctgaaagc tggtaactct aaccaaacag ttgcccttaa
    39421 agaaaaggtt tataaacaac tcttgcagaa atcagatgga tttgtaggaa atctttttaa
    39481 agcatagatt gtattaaata gatgagtaaa aaaggtagat taagtttttc ttgatctgcc
    39541 tttttatgct atacttaagg tatgcataga aaaacagtga ttgattttag gactttgggg
    39601 gagagatata cctttaccca gcctattaaa gagttgaaaa cgagaaatgt agaagaagtg
    39661 gcagatttgc tggcacaagt ggaaagctac caagagcaag gttattatgt ggtggggtat
    39721 gtcagctacg aggctgcacc tgcttttgag gagaaattag cagttcacaa ggttcctcta
    39781 ctgggcgagt acttgcttta ctttactgtt cacgataggg tagagacctc ccctattcct
    39841 ctgacttatg aggatattga tttgccctca aattggcagg aagtgacgtc tgcagcagac
    39901 tatgaaaagg ccattgccca gatacaccat cacttgaggc agggagacac ctatcaggtc
    39961 aactacaccg tccaactcaa gcaaaagtta agtgccaatc cttttgccat ctacaatcgt
    40021 atggtggtag agcaggaggc gggctacaat gcctatgtgg aacatgacga gatggcagtg
    40081 atttccatga gcccagagct cttttttgag caaaatgatc gcgagttgac aacacgacca
    40141 atgaagggga cgactcagcg tggggtaact gaccaagaag atcttgaaca ggccagttgg
    40201 ttggaacagg atcccaaaaa tcgctctgaa aatatgatga ttgtggacct cttgcgcaat
    40261 gatatgaacc gtatttctga agttgggagc gagcacgtgg agcgtctgtg tcaggtagag
    40321 cagtattcaa ctgtttggca gatgacttcg accatcaaga gtcagttgcg agaggatgtg
    40381 gaccttgttg aaatcttccg ctcactcttt ccttgtggtt ccataacggg tgcaccgaaa
    40441 attgcgacaa tggagattat caaggacttg gagcctcaac cgcgtggagt ctactgtgga
    40501 acgattggtc tcttgcttcc aaatggacga cggattttta atgtggccat tcgtaccatt
    40561 caacttcaca aaggtcaagc catttatgga gttggcggag ggattacttg ggatagcaca
    40621 tgggaatctg aataccgaga ggttcatcaa aaggcagcag ttctttatcg taaacaagct
    40681 cgcttccaac tgattacgac aggggaaatc agccagaaga acctgctgtt tgaagatcaa
    40741 catctggaaa gactgagaaa agctagtcgt tattttgctt ttccttttga tgcagaagac
    40801 ttgggacaca agattgagga agagtgtcag gattgtgaag ctaatcgaga ttaccgcttg
    40861 cgaatcagcc ttagcaaatc tggagagata gaagtcaatc gtcaagtatt aacccctctc
    40921 agtacaagct tttgtcaggc ccaagtctgt cttcaggaag ctgctttgaa tcaatccttt
    40981 acctacttta aaaccactca ccgaccgcat ttgagcctag gagaacaaga gaagatttac
    41041 cacaataagt caggagaact gcttgaaacc tctataggaa atttggttct gaaaatcgct
    41101 ggaaaactct acacaccgcc tatccgactt ggaatcttgc caggaattta ccgtcagcat
    41161 ttgctagaaa caggacaggt agaagagaaa gtcttgacct tggcagattt aacccaagca
    41221 gaagctattt acggctgtaa tgcagtgaga ggcttgtatg aactaagcct tgaggagaac
    41281 tagatgaaat tgatattttt gcatgggtta gggcagtcag cagagtcttg gaaagaagtt
    41341 cggaatctac tgacagatta tccttctgag gctatcgagt tatttccttc tggagttagt
    41401 aactatcaac aagctaaaga gcgagtttat cagcacctag ctcaagagac agaacctttt
    41461 gttttgattg gattgtcctt aggtgctgcc ctgacactag aactttccag ttacgattta
    41521 ccaaatcttc gagctttgat tctgtcagga tgcccgctta aattagcagg gaatatccta
    41581 ttttatcttc aattgctgat ttttaaacta cttcccaaaa gagtatttga aaaacaggga
    41641 gcagacaaga ctcttatggt cggagtttct gaggaattga agacacttga tttaacggat
    41701 atagcaggga cttgctccta tccaacctta ctaatttgtg gcagcaaaga taaaccgaat
    41761 cttagttcta tgaaagctct ccatagactg ttaacagatt cgcagtttca gatcattcct
    41821 gatggccctc atgtcttgaa taaggcaaaa ccaaaggagt ttgtagaaaa gaccagaagt
    41881 ttccttgaat tgctgaaata agtttgataa aataatattg aaatcgatat cataattatg
    41941 ggagaaagaa atgaataaac gtctattttt aaaaatgagt ctggtgacgt tgccaatttt
    42001 agccttgttt tcacaaccag ttttggcgga agaaaacatc catttttcga gctgtaagga
    42061 agcttgggcg aatggctatt cggatattca cgagggggaa cctggttatt ctgccaagtt
    42121 agaccgtgat catgatggtg tggcttgcga attgaaaaat gctcctaagg gtgcttttaa
    42181 agcaaaacag tcaacggcta ttcaaatcaa cacaagttca gcaacaacaa gtggttgggt
    42241 taagcaggac ggcgcttggt actactttga tggaaatgga aatctagtga aaaatgcatg
    42301 gcagggaagc tattacctga aagctgatgg taaaatggca cagagtgaat ggatttatga
    42361 ctcttcttat caagcttggt attatttgaa atcagatggt tcttatgcaa aaaatgcatg
    42421 gcaaggagct tattacctta aatcaaacgg taaaatggca caaggtgagt gggtttatga
    42481 ttcttcttac caagcatggt attacttgaa atcagatggt tcatatgctc gcaatgcatg
    42541 gcaaggaaac tactatttga aatcagatgg taaaatggct aaaggtgaat gggtttatga
    42601 tgccacctat caagcttggt attatttgac atcagatggt tcttatgctt acagtacatg
    42661 gcaaggaaat tactatctaa aatcggatgg taaaatggct gtcaatgaat gggttgatgg
    42721 tggacgttat tatgttggcg ctgacggagt ttggaaggaa ggtcaagcaa gtacagcttc
    42781 ttctagtaat gatagcaata gtgaatattc tgctgcttta ggaaaggcaa aaagttataa
    42841 ttcgttattc cacatgtcaa aaaaaacgta tgtatagaca attaacttct gattttgata
    42901 aattttcaaa tgatgcagct caatatgcca ttgatcatta gatgattaac agatactggt
    42961 aggcgaaaaa attccttata attcacttac gcaaaccttt gcataagtga atggattttg
    43021 atatactagt actgtaagca ttttcaatta ctacacaatg aaaaaggaga atatgatgag
    43081 tcaaaagatt attgggattg accttggtgg aacttctatc aaatttgcaa tcttaacaac
    43141 agcaggagaa atccaaggaa aatggtcaat caagaccaac attttggatg agggaagtca
    43201 tatcgttgat gatatgattg agtctattca acatcgtttg gacttgcttg gattggcagc
    43261 agcggacttc caaggcattg gaatgggatc accaggtgtg gttgaccgtg acaaagggac
    43321 tgttatcggt gcctacaact tgaactggaa aacccttcaa ccaatcaaac aaaagattga
    43381 aaaagccttg ggcattccat ttttcatcga taatgatgcc aacgtagcag ctcttggtga
    43441 gcgctggatg ggtgctggag ataaccaacc agacgttgtc tttatgacac tcggtactgg
    43501 tgttggtggt ggtattgtcg cagaaggcaa attgcttcat ggtgttgctg gtgcagcagg
    43561 tgaacttggt catatcactg ttgattttga ccaaccaatt gcatgtactt gtggtaaaaa
    43621 aggctgcctt gagacagttg cttcagcaac aggaattgtc aacttgactc gtcgctatgc
    43681 cgatgaatac gaaggcgatg cagccttgaa acgcttgatt gataacggag aagaagtaac
    43741 tgctaagact gtctttgatc tcgcaaaaga aggagacgac cttgctttga ttgtttaccg
    43801 taacttctca cgttacttgg gaatcgcttg tgctaacatt ggttcaatcc taaacccatc
    43861 aacaatcgtc atcggtggtg gtgtgtcagc tgcgggagaa ttccttctac aaggtgttca
    43921 aaaagtctat gatgaaaata ctttcccaca agtacgcaca tctactaaat tagctcttgc
    43981 aactctagga aatgacgctg gagttatcgg agcagcatca cttgtattgc aataagataa
    44041 tgagagagga aaaatgctaa cctagagtta gtaatgttcc tcttttattt tttatgctat
    44101 actagttagg acaatgaatg aggtgagagt aaatgacaaa agcagatacg atttttaaag
    44161 agaatattga acgcattcta aaggaaggtg ttttctcaga gcaggctcgt cctaagtaca
    44221 aggatgggac tgttgctaat tccaagtatg taactggtgc cttttccgag tacgacttat
    44281 ctaaaggaga atttcctatc acaaccttgc gtcccattgc aatcaaatcc gccatcaaag
    44341 aagttctctg gatttaccaa gaccagtcaa atagcttaga agtgcttaat gacaagtaca
    44401 atgttcacta ctggaatgac tgggaagttg gagacacggg aaccattggt gagcgctatg
    44461 gtgccgttgt taagaaacac gacattatca ataagcttct caaacagttg gaaaccaatc
    44521 cttggaatcg ccgcaatatt atttcgctct gggattacca agctttcgaa gaaacagatg
    44581 ggctgctccc gtgcgccttt cagaccatgt ttgatgtccg gcgtgttgat ggggaaatct
    44641 atctggatgc gaccttgacc cagcgctcca atgatatgct ggtggcccac cacatcaacg
    44701 ctatgcagta tgtggcttta cagatgatga ttgccaaaca ttttggttgg aaggttggga
    44761 agttcttcta tttcatcaac aacctccata tctatgataa tcaatttgaa caagctcagg
    44821 aattgctccg tcgggagccg tcaaactgcc aaccacgctt ggttttaaat gttcctgatg
    44881 ggactaattt ctttgatatc aaagcagaag attttgagtt ggtggattat gaccctgtta
    44941 agccacagtt gaagtttgac ctagctattt aaaagaatag aaaaaagaag ttgagaataa
    45001 tcccaacttc ttttgtttct taacgtgata cgcggcgacg agctgctttt ttacgatttt
    45061 cttcgatgaa agctgctttt tgctcttctg gttcgattac tttcttttta aatgcgtata
    45121 ctgcacctgc aacggcagcg acagttcctg cgacacctgt tacaagacct ttagcgaatc
    45181 ctttagccat gagtcttcct cctttatatt ctcaatcagc cagcctcctc aagaggtcac
    45241 atttttctga ctgacctttt tgtgttataa taatagtaac gaaaaaatgg gaatttttca
    45301 aggaaaaaag atgaaaacaa aaataattgt gattgttgga ccgactgctg ttggaaagac
    45361 ggctctagct attgaagttg caaagcgctt taatggcgaa gtggttagtg gagatagcca
    45421 gcaagtctat cgaggacttg atattgggac ggccaaggct agtccagaag agcaggcagc
    45481 tgttcctcat catttaatcg atgttagaga gataaccgag tcttactcgg cttttgattt
    45541 tgtttcagaa gctaagatga ctattgagga tattcagagc cgtggcaagc tagccattat
    45601 cgccggtggg actggacttt atatccagag cttgctagaa ggttaccacc taggtgggga
    45661 gactccttat gaggagattt tagcttatcg agctagtttg gagccatatt cagatgagga
    45721 attagcccat ttggtggagc aagcaggcct tgagattccc cagtttaatc gtcgtcgtgc
    45781 tatgcgtgcc ttagaaattg cccattttgg tcaggatttg gaaaatcaag agatcttgta
    45841 tgaaccgctg attatctgct tggatgatga acgtagtcaa ctttatgagc gtatcaacca
    45901 ccgagtggat ttgatgtttg aggctgggct tttggatgag gccaagtggc tgtttgacca
    45961 ttcccctaat gtacaggctg ctaaaggaat tggctataag gaactctttc cttatttccg
    46021 tggagagcag acctttgagg aagctcgtga gagtcttaaa caggcgaccc gtcgttttgc
    46081 caagcgtcag ctgacctggt tccgtaatcg catgcaggtc accttttatc agattggaga
    46141 atctggtgta caagaccgca ttttaagcca gatagaggag tttttagatg attgaaacgg
    46201 agaaaaaaga ggagcgagtc ctgctgattg gtgtggaatt gcagggtatg gacagttttg
    46261 acctctccat ggaagaattg gctagtttag cgaaaacggc aggggcagtc gttgtagata
    46321 gctacagaca aaaacgtgaa aaatatgatt ccaagacctt cgtcggctct ggtaagttgg
    46381 aagagattgc gcttatggtg gatgcagaag aaatcactac tgtcatcgtc aacaaccgtc
    46441 tgaccccaag gcagaatgtc aatctagagg aagttctcgg tgttaaggtc attgaccgta
    46501 tgcagttgat tttggatatc tttgccatgc gggctcgaag ccatgaaggg aagctccaag
    46561 tccacctagc ccaactcaaa tacctcttgc ctcgcttggt tggtcagggg attatgctca
    46621 gccgtcaggc agggggaatt ggttcccgtg gtcctggtga aagccagctg gagctgaacc
    46681 gtcgtagcgt tcgcaatcaa atcacggata tcgagcgcca gctcaaggtg gttgagaaaa
    46741 atcgggcgac tgtcagagaa aaacgtttgg agtctagcac ctttaagatt ggtttgattg
    46801 gttataccaa tgctgggaaa tcaactatca tgaacatctt gaccagtaag acccagtatg
    46861 aagcagatga gctctttgcg actctggatg cgacaaccaa gagtattcat ctgggaggca
    46921 atctccaagt aactttgaca gataccgttg gctttattca agatttgccg acagagttgg
    46981 tgtccagttt caagtcaacc ttggaagaaa gcaagcatgt ggaccttctg gttcatgtta
    47041 tcgatgctag caatccttac cacgaggagc atgaaaaaac ggttctctcc atcatgaaag
    47101 acctggacat ggaagatatt cctcacttga cgctttataa taaagcggat ttggtggagg
    47161 atttcacgcc tacccaaacg ccatataccc tcatttctgc caagtctgag gacagtcgtg
    47221 aaaacttgca agcattattg ctagataaga ttaaggaaat ttttgaagca tttaccctgc
    47281 gagtgccttt ttcaaagtcc tacaagattc atgatttaga gagtgttgca attctggaag
    47341 aacgtgatta tcaggaagac ggcgaagtga ttacaggcta catttccgag aaaaataaat
    47401 ggaggttaga agaattttat gactgatatt aaaactttgg ctctaaagta tggaggttat
    47461 acaagtctgg acaaggtcta tctggatcag cttctagctg gtaaaacaga gcaggagcag
    47521 ttaacactta ttacacctcc gccaagtgtt gttaatgcct actttgcaga actctatcag
    47581 aaaaaaagtc ctcaggctgc gacggattat tttgcagaac tcagtcagga actgaatctt
    47641 tacaatactg agccaagttt caccctagaa aataagcctt ttattcggct taatctgtct
    47701 ggtaaatcct ttggtttttg ttatgagagt gacggctttg gtcggatttt ctctgaaaat
    47761 gaggagaaaa tctcggatga cttgctcttt gaaattgcgc aaattttctc ccatcaatta
    47821 gtctttgaag agtctggtaa gatttacatg aagcctgtca aggacgagga agttgtcagc
    47881 ctagaaagtc tcacagcttt gactgatttg gaaagattgg ctgatggtcg aaaacgtctc
    47941 aaaggctaca gccaagagga tttattgcaa gaagctgctg ctttttctgg caaacgctat
    48001 ttccgatcgg aaaaccgcac agccatgtta tatattgatt aattagaaag tatcgaatgg
    48061 atattcaatt tttaggaacg ggggctggtc agccctctaa agcccgcaac gtttcaagtc
    48121 tcgccctgaa acttttggac gagattaacg aagtttggct ctttgactgt ggagaaggta
    48181 cgcaaaatcg cattctggaa accacaattc gaccacgtaa ggtcagcaaa atctttatta
    48241 cccatctgca tggagaccac atttttggtt tgccaggttt cctttctagc cgtgcctttc
    48301 aggccaatga agagcagaca gatttggaaa tctacggacc tcaaggaatc aagtcatttg
    48361 tcttaaccag ccttcgtgtg tcaggttctc gtctgcccta ccgcattcat ttccatgagt
    48421 ttgaccaaga ttctctgggt aaaattcttg aaaccgataa attcactgtg tatgcagagg
    48481 agctggacca cactattttc tgtgttggct atcgtgtcat gcaaaaggat ctagaaggga
    48541 cgctggatgc tgaaaaactc aaggctgctg gtgttccgtt cggcccgctt tttggtaaaa
    48601 tcaaaaacgg ccaggatctt gttttggaag acggaactga aatcaaggca gcagactata
    48661 tctcagcgcc acgtccaggt aagattatca ctattttagg agacactcga aaaacggatg
    48721 ccagtgtgcg tctggctgtc aatgcagatg tcctagttca tgagtccact tatggcaagg
    48781 gtgatgaaaa aattgctcgt aaccatggtc actcaactaa tatgcaagct gcacaagtag
    48841 cggtagaagc aggtgccaaa cgcctcctac tcaaccatat cagtgcccgt ttcctctcaa
    48901 aagatataag caaactcaag aaggacgctg ccacaatttt tgaaaatgtc catgtggtca
    48961 aagacttgga agaagtggaa atctagcagt cacagaaagg ataagtatgc ctactattct
    49021 cattaccgga gctagcggtg gtctagctca agaaatggtc aaactcctgc ccaatgacca
    49081 actcatcttg cttggtagaa ataaggaaaa attagcccaa ctctacggaa attattccca
    49141 tgcagaattg attgaaattg atattaccga cgattcagcc ctagaagctc tggtaactga
    49201 tctttatctc cgctatggca agattgatgt cttgattaac aacgctggtt acgggatttt
    49261 tgagggattt gaccagattg ctgataaaga tattcaccag atgtttgagg tcaatacctt
    49321 tgccctgatg aatctgtctc gtcaccttgc ggctcgtatg aaggaaagca gcaaagggca
    49381 tatcatcaac atcgtcagca tggcaggtct aatagctact ggcaagtcta gtctttactc
    49441 agcgaccaag tttgcggcta ttggtttttc aaatgctctg cgactcgaac ttatgcccta
    49501 tggagtctat gtgacaacag tcaatccagg tccaatccga acaggatttt ttgaccaagc
    49561 tgacccagat ggaacttatc ttaaatcggt tgaccgcttc ctcttagagg cagatgcagt
    49621 ggctaaaaag attgtcaaga ttataggcaa aaataaacga gaactcaatc tcccgatttt
    49681 gttgaaccta gcccataagt tttatactct ctttcccaag ctagctgata agttggcagg
    49741 ggaaactttt aattataagt aaaaagaacc aatgtgcagg ttgttgctag cctacatatt
    49801 ggttcttatc atttctcaac tatcaaactg aacttcttct agtagatagt cgataaagcg
    49861 ttcgcccatc ttagataggc tggttttctc atgctggata tagaccagct caatcgggtc
    49921 atcaatatcc agtgggatag aaacgatatt gtctccgttt aggttgctgt tcaaaatccc
    49981 tgtcgcaatg gtataaccat ccaaaccaat caagagatta aagagggtgg cacggtcact
    50041 gaccacaatg gatttcttgt ggtgttcctg agaaagaatc tcttctgaaa agtagaagga
    50101 gttgtgcgtc ccttggtcat agctgaggta agggaaattc tccaaatcag acagtttcac
    50161 cttgtctttc tttgccagag ggttggtctt gctgacaaag atatgcggtt gcgctgtgaa
    50221 gagatggtgg gctagcaggt gattgtcatc cagcatcttg gttaaaacat cacggttgta
    50281 actgtttaag aagaggaccc cgacctcact gcggaagttc ttgacgtcgt cgataatctc
    50341 ccaagtccga gtttcacgaa ggaagagttc gtatttctcc atatcgcttt tcttgagcaa
    50401 agagacaaag gcattgacca caaaggcata gtgttgagac gaaacgctaa agagttcgcg
    50461 gtgggcgaca ggatttttat agcgttcctc cagaagctgg gtctgctcga caacctgacg
    50521 ggcataagag agaaactcca tcccatcacg ggtcaaggtg attcccttgg gattgcggat
    50581 aaagatctca atgcccattt cattttccaa atctcgcact gcattggaga gacttggctg
    50641 agtgataaag agttgcttgg ctgcctcatt catggagcca gtttcgacga ttttgataat
    50701 ataatgtaat tgttgaattc tcatgttttt attgtaccat acttgcctta gaatcgctaa
    50761 agaagatagg aaaataagga gcattgtatg agtctcttct tgaaaaaaac acaaaatttt
    50821 gctagaatga gtcttatgaa aacattctat gatgtgcagc aattcctcaa acgatttggt
    50881 attattgttt acatgggaaa acgcttatat gatattgaac tgatgaagtt ggaactatct
    50941 cggatttacg atgcagggtt gatggataaa ttagactatc tagaggcaga agcagttctt
    51001 cgcagagagc acaaggtaga attggattat attgagaaaa atggagaaaa gaactaatgg
    51061 ttacttggat tttgtgggca cttatactag caatgttggc gtggatgggc tttaactatc
    51121 ttcgtattcg ccgtgcggct aaaattgtgg acaataagga gtttgaagcc ttgattcgta
    51181 cgggtcaatt gattgatttg cgcgacccag cagaattcca cagaaaacat atccttggtg
    51241 cacgcaatat tccttcaagt cagttgaaaa ctagtcttgc agcacttcgt aaagataaac
    51301 ctgtccttct ctacgaaaac caacgtgcgc aacgagttac aaatgcagct ctttacttga
    51361 aaaaacaagg tttttctgag atttatatcc tttcttatgg cttggattct tggaaaggga
    51421 aagtgaagac tagctaacct tatttccaaa ttagtcgaat gataggatga agctattgtt
    51481 ttatagtata attaatttgt ataaaattta aagagttctt agaacatgaa agaaaagaag
    51541 aaaaatccac tttttgtggg tatcttgtcg attattcttg gtttgttatt tccaattgta
    51601 ggcctgattt tgggtatcat aggattggtc ttggctattt cataccaaaa agagtcacaa
    51661 ttagactata aaatagaaaa gattcttaat atcttaggaa ttgtgatttc tgtagttaac
    51721 tggattgtag caatcgcctt aatttttcgg taaataaaag aaaaaagctt tagttttaaa
    51781 gcttttttta ttttatcgac tcatctctaa atagttttta atgatttgta actctttttg
    51841 gttcaaaggg cggtagttac cttctgctaa atctgggttc aatgtgaagt ccccaaattg
    51901 gattctcttg aggctagtca ccttaacacc aaccgagagg aacattttct tgatttgatg
    51961 aaattttcct tctgaaatgg tgatagaggc ttgactgagg gaaggacttg ctgatagaat
    52021 ctctagtctt gcaggtttac agatagtgcc atctaaaaag acaattcctt tttgaaaggt
    52081 ttggatatgg tcaggtgtta gaagtccatt aacctcaact tgataagtct tatcgacatg
    52141 atattgggga tggaggagtt ggaagcccaa gggaccgtta tcggtcaaga gaaggagtcc
    52201 tgttgtatct cggtccagtc ggccgacggc atagagcttg tcagactgga tgtcagatgg
    52261 aagcaagtcc atgacggtcg gaagttcctt gtctttgttg gctgtaacga caccagcagg
    52321 tttatgaagc ataagatagg tgtgttcata gccttgaatg attcgatcct gaaaaaggag
    52381 ttcttgtagt cctgtatcga tattttgagc tagggagcgg gctgggcaac catcgactag
    52441 aatgtcccct ttgagtaagg cttgtttcat ggcctttcgg ctgatttttt cttgagctaa
    52501 taaattatct aaacgcatac tgtgcctatc ttatcataag tcgcttgctt tgaaaaggct
    52561 tgacgtgaaa agaaaagtgg agtgaaaaca tttacacttg cttgagttat gttatttact
    52621 tgaaattatg gtataatcgt tcagttagaa aataaatttt gaatattata gaggaaatca
    52681 tgacaaaatt aagagaagat atccgtaaca ttgcgattat cgcccacgtt gaccacggta
    52741 aaacaaccct ggttgacgaa ttattgaaac aatcagaaac gcttgatgca cgtactgaat
    52801 tggcagagcg tgctatggac tcaaacgata tcgaaaaaga gcgtggaatt accatccttg
    52861 ctaaaaatac tgccgttgct tacaacggaa ctcgtatcaa cattatggac acaccaggac
    52921 acgcggactt cggtggagaa gttgagcgta tcatgaaaat ggttgacggt gttgtcttgg
    52981 tcgtagatgc ctatgaagga accatgccac aaactcgttt cgtattgaaa aaagccttgg
    53041 aacaagacct tgtcccaatc gtggttgtta acaaaatcga taagccatca gctcgtccag
    53101 cagaagtagt ggatgaagtc ttggaacttt tcatcgagct tggtgcagat gacgaccagc
    53161 ttgatttccc agtggtttat gcttcagcga tcaacggaac ttcttcattg tcagatgatc
    53221 cagctgacca agaagcgact atggcaccaa tctttgacac gattatcgac catatcccag
    53281 ctccagtaga taactcagat gagcctttgc agttccaagt gtcacttttg gactacaatg
    53341 acttcgttgg acgtatcggt atcggtcgtg tcttccgtgg tacagttaag gttggggacc
    53401 aagttaccct ttctaaactt gacggtacaa ctaaaaactt ccgtgttaca aaactcttcg
    53461 gtttctttgg tttggaacgt cgtgaaatcc aagaagccaa agcgggtgac ttgattgccg
    53521 tttcaggtat ggaagacatc tttgtcggtg aaaccatcac tccgacagat gcagtagaag
    53581 ctcttccaat cctacacatc gatgagccaa ctcttcaaat gactttcttg gtcaacaact
    53641 caccatttgc tggtaaagaa ggtaaatggg taacttctcg taaggtggaa gaacgcttgc
    53701 aggcagaatt gcaaacagac gtttcccttc gtgttgaccc aactgattca ccagataaat
    53761 ggactgtttc aggacgtgga gaattgcact tgtcaatcct tatcgaaaca atgcgtcgtg
    53821 agggctatga acttcaagta tctcgtccag aagttatcgt aaaagaaatc gacggtgtta
    53881 aatgtgaacc atttgaacgt gtacaaatcg acactccaga agaataccaa gggtctgtta
    53941 tccaaagcct ttctgaacgt aaaggtgaaa tgttggatat gatttcaact ggtaatggtc
    54001 aaactcgttt ggtcttcctt gttccagcgc gtggtttgat tggatactca actgagttct
    54061 tgtcaatgac tcgtggttac ggtatcatga accatacctt cgaccagtac ttgccattga
    54121 ttccagggga aattggtgga cgtcaccgtg gtgcccttgt ttctatcgat gctggtaagg
    54181 ctacaactta ctcaatcatg tctatcgaag aacgtggtac gatctttgtc aacccaggta
    54241 ctgaggttta tgaaggaatg atcatcggcg aaaactctcg tgaaaatgac ttgacagtta
    54301 acatcacgaa ggcaaaacaa atgaccaacg ttcgttcagc tactaaggac caaacagctg
    54361 ttatcaagac gcctcgtatc ttgacacttg aagagtctct tgagttcttg aacgacgatg
    54421 agtacatgga agtaacgcct gagtctatcc gtttgcgtaa acaaatcctt aacaaagcag
    54481 agcgtgagaa agctaacaag aagaaaaaat cagctgaata agagctagaa agagagaaag
    54541 atggtctatt tagtcctagg aattttactg ctcctactct atgtatttgc gacaccagaa
    54601 agcattaaag ggacagtcaa tatcgtcgct atggtatgta ttttagtggc actcttgatt
    54661 ttattggttc tatcttttct gaaaattttt caattaccaa cagaaatatt cctagcaata
    54721 gccatgttga tcctagctta ctttagtgtg agagacatca cactcatgcc agtcaaaaaa
    54781 agtaaaagaa gataaaaaag agagttttgg ctctcttttt tgctaggaat tttacaagat
    54841 tgcaatttat ttttgagtta tcaccatctc ttttgtttgg ataatatgaa tgggaaaaac
    54901 ttgaataaaa ttctttaatg gaatctattt tatatttgct tagtactggt tgcatattat
//
LOCUS       DAVLDI010000006        54781 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLDI010000006 DAVLDI010000000
VERSION     DAVLDI010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54781
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.006"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..881
                     /locus_tag="VXD01_000335"
                     /pseudo
     CDS             1..881
                     /locus_tag="VXD01_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(914..1254)
                     /gene="tnpB"
                     /locus_tag="VXD01_000336"
                     /pseudo
     CDS             complement(914..1254)
                     /gene="tnpB"
                     /locus_tag="VXD01_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1470..2820)
                     /locus_tag="VXD01_000337"
                     /pseudo
     CDS             complement(1470..2820)
                     /locus_tag="VXD01_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(2956..3255)
                     /locus_tag="VXD01_000338"
     CDS             complement(2956..3255)
                     /locus_tag="VXD01_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV0600791.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(3420..3871)
                     /locus_tag="VXD01_000339"
                     /pseudo
     CDS             complement(3420..3871)
                     /locus_tag="VXD01_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            3953..4799
                     /locus_tag="VXD01_000340"
                     /pseudo
     CDS             3953..4799
                     /locus_tag="VXD01_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(5001..7259)
                     /locus_tag="VXD01_000341"
     CDS             complement(5001..7259)
                     /locus_tag="VXD01_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0600792.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(7488..7718)
                     /locus_tag="VXD01_000342"
     CDS             complement(7488..7718)
                     /locus_tag="VXD01_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV0600793.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            7908..8591
                     /locus_tag="VXD01_000343"
     CDS             7908..8591
                     /locus_tag="VXD01_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0600794.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            8591..9325
                     /locus_tag="VXD01_000344"
     CDS             8591..9325
                     /locus_tag="VXD01_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0600795.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGISLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLRKVL"
     gene            9479..10336
                     /locus_tag="VXD01_000345"
     CDS             9479..10336
                     /locus_tag="VXD01_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV0600796.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKIAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDSAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMVPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLTSHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            10478..11350
                     /locus_tag="VXD01_000346"
     CDS             10478..11350
                     /locus_tag="VXD01_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV0600797.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            11632..12315
                     /gene="rpiA"
                     /locus_tag="VXD01_000347"
     CDS             11632..12315
                     /gene="rpiA"
                     /locus_tag="VXD01_000347"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV0600798.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTSKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKIVATPSKEYIWVVDESKLVDKLGAFKLPVEVVQYGAEQIFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIEDPIVFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QILTSRKEK"
     gene            12329..13540
                     /locus_tag="VXD01_000348"
     CDS             12329..13540
                     /locus_tag="VXD01_000348"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV0600799.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            13542..14084
                     /locus_tag="VXD01_000349"
     CDS             13542..14084
                     /locus_tag="VXD01_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV0600800.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            14100..14909
                     /locus_tag="VXD01_000350"
     CDS             14100..14909
                     /locus_tag="VXD01_000350"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0600801.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            15406..17013
                     /locus_tag="VXD01_000351"
     CDS             15406..17013
                     /locus_tag="VXD01_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV0600802.1"
                     /translation="MKESENDAPKLETPLREEPRLAPQTLPEASEVLENKREESKVEI
                     TEPAQDSPILAPVEETKEEAVTEKPTNTRSLTAEDLVKISKGELHLENDLIDESFYGE
                     KALDLEGDDDQDGIKNKDGKDYLGYNSHPLLADSDGDGLADGEDDNKKEWYVTDRDSL
                     LFMELAYRDDDYIEKILYHKNLFPSLYLDRQEHKLMHNELAPFWKMKKAYYTDSGLDA
                     FLFETKSDLPYLKDGTVYMLAIRGTRVNDAKDLSADLVLLGGNKPAQADDIRKVVGEL
                     AKDISITKLYMTGHSLGCYLAQIAAVEAYQKYPDFYNHVLRKVTTFSAPKVITSRTVW
                     NAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKHRSRG
                     YFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPRSSSQPSAEPMENIAL
                     GKQVTQSSTVFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIRQINI
                     YNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            17038..17550
                     /locus_tag="VXD01_000352"
     CDS             17038..17550
                     /locus_tag="VXD01_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV0600803.1"
                     /translation="MSAQITINHKKVRYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            18207..18917
                     /gene="deoD"
                     /locus_tag="VXD01_000353"
     CDS             18207..18917
                     /gene="deoD"
                     /locus_tag="VXD01_000353"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV0600804.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYACELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(18940..19464)
                     /locus_tag="VXD01_000354"
     CDS             complement(18940..19464)
                     /locus_tag="VXD01_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV0600805.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(19517..19753)
                     /locus_tag="VXD01_000355"
     CDS             complement(19517..19753)
                     /locus_tag="VXD01_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV0600806.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(19821..20741)
                     /locus_tag="VXD01_000356"
     CDS             complement(19821..20741)
                     /locus_tag="VXD01_000356"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV0600807.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            20931..21298
                     /locus_tag="VXD01_000357"
                     /pseudo
     CDS             20931..21298
                     /locus_tag="VXD01_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21514..22095
                     /locus_tag="VXD01_000358"
     CDS             21514..22095
                     /locus_tag="VXD01_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0600808.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGQKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLYVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            22092..23369
                     /locus_tag="VXD01_000359"
     CDS             22092..23369
                     /locus_tag="VXD01_000359"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV0600809.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            23387..24049
                     /gene="deoC"
                     /locus_tag="VXD01_000360"
     CDS             23387..24049
                     /gene="deoC"
                     /locus_tag="VXD01_000360"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV0600810.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGSDFVKTSTGFSTGG
                     ATIADVRLMRETVGPDMGVKAAGGARSYADALTFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            24036..24425
                     /locus_tag="VXD01_000361"
     CDS             24036..24425
                     /locus_tag="VXD01_000361"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0600811.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDRSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            24515..25567
                     /locus_tag="VXD01_000362"
     CDS             24515..25567
                     /locus_tag="VXD01_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV0600812.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            25711..27246
                     /locus_tag="VXD01_000363"
     CDS             25711..27246
                     /locus_tag="VXD01_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0600813.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            27239..28297
                     /locus_tag="VXD01_000364"
     CDS             27239..28297
                     /locus_tag="VXD01_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0600814.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            28300..29256
                     /locus_tag="VXD01_000365"
     CDS             28300..29256
                     /locus_tag="VXD01_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0600815.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            29341..30648
                     /locus_tag="VXD01_000366"
                     /pseudo
     CDS             29341..30648
                     /locus_tag="VXD01_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(30691..31332)
                     /gene="plsY"
                     /locus_tag="VXD01_000367"
     CDS             complement(30691..31332)
                     /gene="plsY"
                     /locus_tag="VXD01_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV0600816.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            31468..33411
                     /gene="parE"
                     /locus_tag="VXD01_000368"
     CDS             31468..33411
                     /gene="parE"
                     /locus_tag="VXD01_000368"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV0600817.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            33831..36302
                     /gene="parC"
                     /locus_tag="VXD01_000369"
     CDS             33831..36302
                     /gene="parC"
                     /locus_tag="VXD01_000369"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV0600818.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQTEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            36434..37456
                     /locus_tag="VXD01_000370"
     CDS             36434..37456
                     /locus_tag="VXD01_000370"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV0600819.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            37512..38216
                     /locus_tag="VXD01_000371"
     CDS             37512..38216
                     /locus_tag="VXD01_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0600820.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            38281..38970
                     /locus_tag="VXD01_000372"
     CDS             38281..38970
                     /locus_tag="VXD01_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV0600821.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            38967..39890
                     /locus_tag="VXD01_000373"
     CDS             38967..39890
                     /locus_tag="VXD01_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV0600822.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            39905..40549
                     /gene="pcp"
                     /locus_tag="VXD01_000374"
     CDS             39905..40549
                     /gene="pcp"
                     /locus_tag="VXD01_000374"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV0600823.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            40717..40947
                     /locus_tag="VXD01_000375"
     CDS             40717..40947
                     /locus_tag="VXD01_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV0600824.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            40997..41077
                     /locus_tag="VXD01_000376"
     tRNA            40997..41077
                     /locus_tag="VXD01_000376"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41031..41033,aa:Tyr,seq:gta)
     gene            41087..41158
                     /locus_tag="VXD01_000377"
     tRNA            41087..41158
                     /locus_tag="VXD01_000377"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41119..41121,aa:Gln,seq:ttg)
     gene            41320..42522
                     /gene="rpsA"
                     /locus_tag="VXD01_000378"
     CDS             41320..42522
                     /gene="rpsA"
                     /locus_tag="VXD01_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV0600825.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(42607..43933)
                     /locus_tag="VXD01_000379"
                     /pseudo
     CDS             complement(42607..43933)
                     /locus_tag="VXD01_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            44127..44624
                     /locus_tag="VXD01_000380"
     CDS             44127..44624
                     /locus_tag="VXD01_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV0600826.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            44624..46279
                     /gene="dnaX"
                     /locus_tag="VXD01_000381"
     CDS             44624..46279
                     /gene="dnaX"
                     /locus_tag="VXD01_000381"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV0600827.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVCLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            46307..46501
                     /locus_tag="VXD01_000382"
     CDS             46307..46501
                     /locus_tag="VXD01_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV0600828.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            46651..47421
                     /gene="sufC"
                     /locus_tag="VXD01_000383"
     CDS             46651..47421
                     /gene="sufC"
                     /locus_tag="VXD01_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV0600829.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            47449..48711
                     /gene="sufD"
                     /locus_tag="VXD01_000384"
     CDS             47449..48711
                     /gene="sufD"
                     /locus_tag="VXD01_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV0600830.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            48722..49948
                     /locus_tag="VXD01_000385"
     CDS             48722..49948
                     /locus_tag="VXD01_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0600831.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDRVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            49935..50375
                     /locus_tag="VXD01_000386"
     CDS             49935..50375
                     /locus_tag="VXD01_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV0600832.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            50429..51841
                     /gene="sufB"
                     /locus_tag="VXD01_000387"
     CDS             50429..51841
                     /gene="sufB"
                     /locus_tag="VXD01_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV0600833.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(52072..53313)
                     /locus_tag="VXD01_000388"
     CDS             complement(52072..53313)
                     /locus_tag="VXD01_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV0600834.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIEQI
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            53416..54525
                     /locus_tag="VXD01_000389"
     CDS             53416..54525
                     /locus_tag="VXD01_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV0600835.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
BASE COUNT        16371 a         9868 c        12088 g        16454 t
ORIGIN      
        1 aatcaaacaa cgatttggcg aaatgtaaaa aaatatgagg agttcggact cgactctctc
       61 cttcaagaaa cacgtggtgg tcgtaaccat gcatatatga cgattgagca agagaaagcc
      121 tttcttgccc gtcatttgaa gactacagat gcaggagaat ttgttacaat tgatgcctta
      181 tttcaggctt ataaaaagga gttaggtcgt tcctacacac gtgatgcctt ctatcaactg
      241 ttgaagcgcc atggttggcg aaatattatg ccacgtccag aacatcctag gaaagcagac
      301 gctcaaacca ttgtcgcgtc taaaaataaa atctcaattc aagaagaaaa gaaagcgatt
      361 taaaaccagt agacgttttc gtaaggttcg cttgatgtac caagatgagg ctggtttcgg
      421 tagaatcagt aaactgggat cttgttgggc tccaatagga gtaggtccac atgtccatag
      481 tcactatata cgagaatttc gctattgtta tgcctataca ggcgaatcat ttttcttaat
      541 agctggtgga tgtaatactg agtggatgaa cgccttttta gaagagcttt cacaagctta
      601 tccttttact cgttatggac aatgctatat ggcataaatc aagtacctta aagattccga
      661 ctaatattgg ctttgcattt attcctccgt acacaccaga gatgaacccc attgaacaag
      721 tgtggaaaga gattcgtaaa cgtggattta aaaataaagc ctttcaaact ttggaagatg
      781 tcatgaatca actttaagat atcatacaag gactggagaa ggaggtgata aagcccatcg
      841 ttaatcggag atggactaga atgctttttg aaagcagatg agtataaaaa gaaagtcctc
      901 atttcaatag aaatcacgac tttctgatgg atttattttt ggagtgatag aaaagccctt
      961 cataagccag tctacttgtt caggtgtgag agctttgaca tccttttctg tactgggcca
     1021 agtcagtctg ccgttctcaa agcgtttata tagtagccaa aatccttgac catcccagta
     1081 aagggcttta aagcggtctt tacgtccacc acaaaagaga aagacttgac cggagaaagg
     1141 atccaattca aagtgggttt taactacata ggctaatgag tctattccct gcctcatatc
     1201 tatcttgcta caaacaaggt gaacttgacc taaatcactt agttgaatta tcatagtaca
     1261 atacctttcc tccgataatt attttttatc tagtatactg gaagttgggg aattaggata
     1321 gataccttgt tatgacgcgc ttacgtaact tgtaactagc tgcctagttt gatctttgct
     1381 tcttcattga ttagcagtag atttcaaaat gataaaaacg tataatagta ggtgtagtgt
     1441 actgcccccc aaaaagttag acaattaatt tatccgaagg atttagttct gtattgcaca
     1501 gggctaagtc cttttagttt taccttaatt cgtttattgt tgtagtaatc aatatagtct
     1561 ataatggctt gttccaattg gttaagtgat ttaaatgttt tctcatagcc ataaaacatt
     1621 tcggatttta aaatgccaaa gaaagattcc atcataccgt tgtctttgct gtttcccttg
     1681 cgtgacatag atgcttgaat tcccttactc tctaggaacc gatgataaga atcgtgttga
     1741 tattgccagc cttggtcact atggagaatc gtattctcgt agtgcttctc tgtgaatgcc
     1801 tgttccaaca ttgtttgtac ttgttctaag ttgggtgaag ttgaaagatt ataggcgata
     1861 atttcgctat taaagccatc taaaactggt gataagtaaa gcttttgagt acttactgga
     1921 atggcaaatt cagtcacatc tgtgtagcac tgttccattg ttttagagcc ttcaaattgg
     1981 ccttgaatga gattctctgc tttcttgcca acgtctcctt tatgagaaga atattttcgt
     2041 ttctgtcgcg ttttagcttg taaattgagt acttcatcaa gtgttgaact cttttatgat
     2101 ttaccagata accacgattt cttagttcta aataaatccg acgataacca tagttgcctt
     2161 tatgttcatt ataaatggcc tgaatttagg ttttaatctc tttatcttta tcaaccccat
     2221 ccagttgttt caactgataa tagtaagtcg agcgagctaa acgtgctgtt tcaagaagaa
     2281 aatctagtcg aaatcctcct gaaaccattt ctctaactgt ctctgccttt ctcgctctag
     2341 ggcttcgtcc ctttcctcta actcttttaa cttttttagg taggccacct cagtccgtaa
     2401 gcgttcattc tcctcctgga gtcgttctag ttctgtcatt tcttcccaag tcttcttccg
     2461 tttacgtccc attttagctg gtctccctct tgttttctca acaatagtat acccgttttt
     2521 cttgtattgt gccagccaaa atgaaagcat tccttggttt gggagggcat aatcaagact
     2581 aacacttctt tgtgaacaac cttccagtaa ggctttatcc atcatttctt gtttcaattt
     2641 agaagaatag tgacgattct tccccttttt aacgatttct atgccatgac ggtcaattaa
     2701 tttcaccatg tactttagac cagaaacatc cacaccaaat ctttttgaaa gctgtttgaa
     2761 gctttgtcct tgctttctta gttcatagat ctgaacttta tcttcataac ttaatttcat
     2821 aataaaacac cccaaaagtt agattttttc tgtctaactt ttagggggca gttcatttcg
     2881 gcacctgata ctatgcgttt tgttatggaa agacttattg gactttctct caaatcgagt
     2941 ttttactcaa ttttcttact tgattgggat tgaaattcca attaatttct ctgagtagag
     3001 tgtcttgata ttggcttcat caacagaggt cttatcaatt ttacgtttca agaaaaattc
     3061 ttgaatggtt tcgatttcag gctcacgaat agcacggtgt ttgtttgaga tgaggatttc
     3121 atagtgaagc ggagcttggg taaaaataac atctgtattc cctgcagaat aaacctcaac
     3181 aagggttgca tcggtacttt ctagttgact ttttacaagt tgcgagtgtg agtttgtcgt
     3241 attgataagc ttcataatat ttcctccgat tttctaattc tattataaca ctttttgaat
     3301 aaagtcgctt gatttatact caatgaaaat caaagagcaa actaggaagc tagccgcagg
     3361 ctatacttga gtacggtaag gcgacgctta cgtgatttga attttatttt cgaagagtat
     3421 tagccaatct tatgctgttt tttccaagat tcaatggccc atttatggct gccacgttta
     3481 aggtttttga tagcctcgtc aatagggaac caggcaatat gattaaagtt ttctagtggc
     3541 ttttgtactt ctttgaaagg agttgcttca tagaggtagg caggattgta gtagtaggta
     3601 tcacgatgac gagaatagaa atattcgtca gctggtccgt aataggtacc aatttctgct
     3661 gtgaaaccaa gctcttcaat caactcacgc tttagggctt cctgatgatt ttcacctgct
     3721 tcaatttttc cacatggtag gaaccaagca ccatttggtt cttgaacaag aacaatttgt
     3781 ttttgttcag gattagggat aactgcatat acgccatagc gagcaatata gtctgtattc
     3841 actttttttc tccgaaagtt gggtttgcca ttgcattttc ctcattatct agtatcgtta
     3901 ttattatagt gaaatgaacc aaaaatagta cacaatgtgg tataatcttc ttatggcata
     3961 ttcaatagat tttcgtaaaa aagttctctc ttattgtgag cgaacaggta gtataacaga
     4021 agcatcacac gttttccaaa tctcacgtaa taccatttat ggctggttaa agctaaaaga
     4081 gaaaacagga gagctaaacc accaagtaaa aggaacaaaa ccaagaaaag ttgatagaga
     4141 tagacttaaa aactatctta ctgacaatcc agacgcttat ttgactgaaa tagcttctga
     4201 atttggctgt catccaacta ccatccacta tgcgctcaaa gctatgggtt acactcgaaa
     4261 aaaagaacca cacctactat gaacaagagc cagaaaaagt agccttattt cttaagaatt
     4321 ttaatagatt aaagcaccta gcacctgttt agattgacga aacaggattc gatacttatt
     4381 tttatcgaga atatggtcgc tcattaaaag gtcagttaat aagaggtaaa gtatctggaa
     4441 gaagatatca gaggatttct ttggttgcag gtctaacaaa tggtgagtta atcgctccaa
     4501 tgacttacga agagatgatg acgagcgact tttttgaagc ttggtttcag aagtttttct
     4561 taccaacatt aaccacacca tcggttatta ttatggataa tgtaagattc catagaatgg
     4621 ggaagctaga acttttatgc gaagagtttg ggcataaact tttacctctt cctccctact
     4681 cgcctgagta caatcctatt gagaaaacat gggctcatat caaaaagcac ctcaaaaagg
     4741 tattaccaag ttgcaatacc ttttacgagg ctcttttgtc ctgttcttgt ttcaattgac
     4801 tatagcagat tgaaatgaga acaaatcgat tgggaaagta aaattaattt ctataaatgt
     4861 tttagcaatt gtttcgtact atttcagatt cagtctacta tatatcataa tggacaaagg
     4921 gcaagctgtc aagaaattac agttatttta gtaaaaaaag aagcagaaaa atttcatttt
     4981 ctactccttt tctataggat ttatttttct ttttcagaac ttttaacttc agcttttttg
     5041 gcagatttaa tctgaatgtt tcccttgcta gtcataactg ctttgagatc tttttcgctt
     5101 ggattttcaa ggtagtagtc agtgattgtg tcctcaatat agtcttgaat agtccgacga
     5161 agtgggcgtg ctcccatttt tggatcataa cctaggtcaa ccaacttttc cttgacctta
     5221 tcagttacat ccaaacgaat gttgttgcta gagaggcgct tgttaacatc tgctagcatg
     5281 agctcgacaa tctgaaggag gttatccttg ctgagagcct taaattcgat aatgccatca
     5341 aaacggttca taaactctgg gctaaagaag ttaccgagtt caccgaggac agaattggta
     5401 cgtccttctc tagcagcacc aaatccaacg ctagcttcgg tctttcctgt acctgcattt
     5461 gaggtcatga taatgatggc atccttgaag ctaacggtgc gtccttgccc gtctgtcaaa
     5521 cgaccatcgt ccaagacttg aagaaacatg tgcataacat ctgggtgagc tttttccact
     5581 tcatcgagaa ggatgagaga atatggattg tggcgaactt tttcagttaa ttgaccagcc
     5641 tcatcatagc caacataacc tggaggggcg ccgaccaact tagccacact atgtttttcc
     5701 atgtattcac tcatatcaaa gcgaatcata ctatcagcag aaccaaaaag ttcgatagcc
     5761 agttgtttgg aaagttctgt cttaccgaca ccagttggcc caacgaagag gaagcttccg
     5821 attgggcggt taggggtacc aagtccgaca cgattacggc gaatagcctt ggcaatctta
     5881 tcgactgcat catcttggcc aataacatga gacttgagat cttcggctag atggatgagt
     5941 tgagattgtt ctttctcttt caaatcacca acagggatat tggttttctg ctcgataatg
     6001 tgctcaatag ttttctcgct gatgatagga gtatcctggt ctgtgatctt tttcttttgc
     6061 atttccttat acttggcaat ctggtcgcgg aagtaggccg ccttctcaaa atcttcttct
     6121 cgtgtagctt gagacttgag attttcagcc tcaatcaagc gctgatcaat tactttagga
     6181 tccacaaaat tcaaggtcaa gttcatctta gaaccagctt catctaggag gtcaatggcc
     6241 ttgtcaggca agaagcgatc ttggatgtag cgattggaaa gagttgcagc tgcttcaatc
     6301 gcagcatcgg tatattgaac gtggtggtaa tcttcgtatt tcttttgaat ccctttgaga
     6361 atagtgattg tttcatccac cgttggttca tcgactttaa caggctgcat acgacgctcg
     6421 agggcagcat ccttttcaat gatacggtat tcattgaggg tagtagcacc gactagttgc
     6481 agttctccac gagcaagggc tggcttgagg atatttcctg cgtccatatt accatcactc
     6541 gcagaaccag caccaacaat ttcatggatt tcatcgataa agaggatgat gtcttcacgt
     6601 ttgcgaattt cttccatgag tttttgcatg cgttcttcaa attgtcctcg aatccccgtt
     6661 ccttgaacta agctaaccac atccagacgg atgacttgtt taccttggag tttatgtggc
     6721 acatcgccat cgacaatttt ctgagctaga ccttcgacaa cggccgtttt tccgacacca
     6781 ggttcaccga taaggacagg attattcttg gttctacgat tgagaatctc gatgacacgg
     6841 ataatctcat cgtcgcgccc aataacgggg tcaatgtctc cacgacgggc aatttcagtt
     6901 acattaatac caaattcttc cagcaggcct ttttcttggc taggtggcgg agtttgagca
     6961 gatccacgat tttgggaacc ataaccgccg tttccaccgt aacctccacc tgattgggtt
     7021 gggggaatag gaggagtatt gctagaaggt ctgaaattgt ttagatcatt gaagaaatca
     7081 ccaaagggat cgaagtcacg attgttcaga tccgtcatac ctttgaagag gctattgtta
     7141 ggatctgttt tgataatctt atagcagttt tgacagaggt caatttgttt ttgttttcca
     7201 ttgagattgg tgtaaagatg aattgttgag tcgttaattt tacagttttg acaaagcata
     7261 catctacctc atttctttct ttagcctgac ttgtttaaag gtcaaaaata gtcaaattct
     7321 atactctcat tataacagga ttggggtgta aagcaagtaa aaagattgaa gctttgagaa
     7381 gttgttacaa tgaaaatttt tgtgaatttg gactataaaa aaatcctatt tgtgagacaa
     7441 aaaggatttt acttagacat gcagggacaa tcccagcttg ttttagatta gtagagaagt
     7501 tcgtaaattt ccattgcgat taagtcaatg ctatcaaacg tatacgtttc gcgatcttct
     7561 acgtcacgaa gggtaaagat tgggccgttt tcttcgtcgt ggctgtacgc aacttctgca
     7621 acaacaactc cttcgcgttc aaaattacgt tttaaatttc cgccatcgtt tgccattgct
     7681 tcaaggcggt tgatgattct aaccaaatgt gattccattt tgattctcct tcatttctta
     7741 tcgttactat tttaccataa aggaggccaa cttgactaga aaaaactaag atttctcgct
     7801 aattctgcta gtttaaagat ttttaaataa attggataaa aaatttaaat tttaattcaa
     7861 aacatgttat aatcatacag tattctattt tagaaagcag tgtgactatg aatttttctt
     7921 ttttacctaa gtatttacct tattttaact atggggctgt tgtgacgatt cttatttcta
     7981 tctgtgttat ctttttggga actattttgg gtgttgtctt ggcttttggg caacgttcaa
     8041 agtttaaacc gcttgtttgg ttggccaact tgtacgtttg gattttccgt gggacaccga
     8101 tgatggttca aattatgatt gcctttgctc ttatgcatat caatgctccg actattcaga
     8161 ttggaatttt aggtgttgat ttttcgcgtc tgattccagg gattttgatt atctctatga
     8221 atagtggtgc ttatgtttcg gagactgttc gtgccggaat caatgcggtt ccaaaaggtc
     8281 agctagaggc ggcttattcg ctagggattc gtcctaaaaa tgcgatgcgt tatgtgattt
     8341 tgccacaagc agtcaaaaat atcttgccag cattggggaa cgaatttatc accattatca
     8401 aggacagctc cctcttatca gctattgggg tcatggagtt gtggaatggg gctacaacag
     8461 tttctacaac aacctatcta cctttaacac cacttttatt tgcagcattt tactacttga
     8521 ttatgacctc tattctgaca gtagccttga aagcttttga aaaacatatg ggacaaggag
     8581 ataagaaata atgacagaaa ccttgataaa aattgaaaat ttacataaat cttttggaaa
     8641 gaatgaagta ttgaagggca tcagcctcga gattaaaaga ggagaagttg tcgttatcat
     8701 cggtccttca gggagtggga aatctacctt gcttcgctct atgaatttgt tggaggaagc
     8761 aaccaagggg aaggttatct ttgagggagt cgatattacg gacaagaaga atgacctgtt
     8821 tgccatgcgt gagaagatgg gcatggtttt ccaacaattt aacctctttc ctaatatgac
     8881 tgtgatggaa aatattacct tgtcacctat caagactaaa ggtgaaagca gggaagttgc
     8941 tgagaagaga gcccaagagc ttttggaaaa agttggtttg ccagataagg cagacgctta
     9001 tccacagagt ctgtcgggtg ggcaacaaca acggattgcc atcgcgcgtg ggttggctat
     9061 ggaaccagat gttttgctct ttgacgaacc aacttcagcc ttggatcctg aaatggtagg
     9121 tgaggtattg gctgttatgc aagaccttgc caagtcaggg atgactatgg ttatcgtaac
     9181 acatgagatg ggatttgccc gtgaggtggc agatcgtgtt atctttatgg cagacggtgt
     9241 ggttgttgaa gatgggacac ctgagcagat ttttgaacaa acccaagaac aacggactaa
     9301 agatttcttg agaaaggttt tataatctat tttaaaattt caagacaaga ttagtgaaaa
     9361 gttcaaccag agctttttct tatagtttga aactatagga taacctagga aagaagtgtt
     9421 agagggcact agcagttttt ggtataatgg aagatatttg aaagaaaaga gaagtgatat
     9481 gacacagatt attgatggaa aagctttagc ggccaaattg caggggcagt tggctgaaaa
     9541 gattgcaaaa ttaaaggaag aaacagctct agtgcctggt ttggtagtga ttttggttgg
     9601 ggataatcca gccagccaag tctacgttcg caacaaggag aggtcagctc ttgcggctgg
     9661 ttcccgtagc gaagtagtgc gagttccaga gaccattact caagaggaat tgttagacct
     9721 gattgctaaa tataatcagg attcagcttg gcatgggatt ttggtccagt tgccattacc
     9781 aaaacatatc gatgaagagg cggttttatt agccattgac ccagaaaagg atgtggatgg
     9841 tttccatccc ctaaacatgg gacgtctttg gtctggacat ccagtcatgg ttccctcgac
     9901 acctgcagga attatggaaa tgtttcatga atatgggatt gacttggaag gtaaaaatgc
     9961 ggtcgtaatc ggtcgttcaa atatcgttgg aaaacctatg gctcagcttc ttttggctaa
    10021 aaatgcgaca gtaaccttga cccactcacg aactcataat cttgccaagg tggctgctaa
    10081 agcagatatt cttgtagtcg caatcggccg cgccaagttt gtgactgctg actttgtcaa
    10141 accaggtgcg gttgtcattg acgttgggat gaaccgagat gaaaatggga agctctgtgg
    10201 agatgttgat tatgaggcag ttgcaccact tactagccat atcacgccag tccctggagg
    10261 tgtcggtcct atgaccatta ccatgctgat ggagcaaact tatcaagcag cacttcggac
    10321 attggataga aaataagaga aacattcgat taatagagtg tattttctat agctatatct
    10381 aaaatggcag aaatgaatat taaattttag atataagatt acaaaaggag gtctgcgtct
    10441 cctttttatt gtataataaa agtgagagga aaaaaggatg aaagtgatta atcaaacctt
    10501 attagaaaaa gttattattg aacgttctcg ttcaagtcat aaaggagatt atggtcgtct
    10561 gctgctgctt ggtggtactt atccttatgg aggtgccatc atcatggctg ctttagcagc
    10621 tgtaaaaagc ggtgcaggat tggtgaccgt tggaacggac agggaaaata tcccggctct
    10681 gcacagccat ttacctgagc ctatggcctt ttctcttcaa gaccagcaat tgttaaaaga
    10741 gcaattggag aaggcagaag ttgtcttgct ggggcctggt ttacgagacg atgcttctgg
    10801 agaaaatcta gtaaaacagg tctttgttaa tttaagccaa aatcagattt tgattgtaga
    10861 cggaggtgcc ttgaccattc ttgctaggac aagtttgtca tttccctcaa gccagcttat
    10921 cctaactcct caccaaaaag aatgggaaaa attatctgga attacgattg aaaagcaaaa
    10981 ggaagatgca acggctagtg ttctgacttc cttccctcaa ggaacaattt tggtggagaa
    11041 aggcccagct actcgtattt gggaagttgg ccaatctgat tattaccagt tacaggttgg
    11101 tggtccttat caggcgactg ggggaatggg agatactctg gctgggatga tcgcaggatt
    11161 tgtaggccaa ttccgacagg ccagtctcta cgagcgtgtg gcagtagcga cccatcttca
    11221 ttcagccata gcccaagaac tatctcaaga aaattatgtg gtcttaccga cggaaatcag
    11281 caggtatctt cccaaaataa tgaaaattat ttgtcaacaa gagagggtaa gtaaagataa
    11341 acttgtttaa aatagacaga taaatctact tccttctctt aatttatgat tcttgaaatg
    11401 cgcctgcttt aaggctaaac tagacgtatc aaagttaaga gtttgttttt gtaactggaa
    11461 agagatgaac aaatcaaata cataaaagat aaactcattt ttattcgttt ggtgaaaaga
    11521 aaatacatat ttttaaagaa agattgatga aaaatgtaga tttgatgttt ttacttgaat
    11581 aaaaagcggt ttcatagtaa aataagaact gagaatgatg gaggtaaatc ggtggaaaat
    11641 ctgaagaaaa tggcaggtat caaggctgct gagttcgtga gcgatggaat ggtcgttgga
    11701 ctgggaacgg gttctactgc ctattatttt gtcgaagaaa ttggtcgtcg tatcaaggaa
    11761 gaaggattgc agattacagc tgtaacgact tctagtgtga ccagtaaaca ggctgaaggg
    11821 cttaacattc cactcaagtc tattgaccaa gtagactttg tcgatgtgac agtcgacgga
    11881 gcggatgaag tagatagtca gtttaatgga atcaaaggcg gtggtggtgc ccttctgatg
    11941 gagaagattg ttgcaacgcc ctcaaaagaa tacatttggg tagtggatga aagcaagctg
    12001 gtagacaaac taggtgcttt taaattgcct gtggaagtgg ttcaatatgg tgcagaacag
    12061 atttttcgtc gttttgagcg agctggctac aaaccaagtt tccgtgaaaa agatggccaa
    12121 cgttttgtga ccgatatgca gaactttatc attgaccttg ccttggatgt catcgaagat
    12181 ccaattgttt ttggacaaga attggaccat gtcgttggtg ttgtagaaca cggtttattc
    12241 aaccaaatgg tggacaaggt cattgttgct ggacgagatg gggttcagat tttaacctca
    12301 agaaaagaaa aatagaaggg ggcataagat gtctaaattt aatcgtattc acttggtggt
    12361 attggattct gtaggaattg gtgctgcacc agatgctaat aactttgtca atgcaggggt
    12421 tccagatggt gcctctgaca cactgggaca catttccaaa accgttggtt tgaatgtccc
    12481 aaacatggct aaaatcggtc ttggaaatat tcctcgcgaa acgcctttga agactgtagc
    12541 agctgaaagc aatccaacag gatatgcgac gaaattggaa gaagtatccc ttggtaagga
    12601 taccatgact ggtcactggg aaatcatggg actcaacatt acggagcctt tcgatacttt
    12661 ctggaacgga ttcccagaag aaatcctgac aaaaatcgaa gaattttcag gacgtaaggt
    12721 cattcgtgaa gccaacaaac cttactcagg aacagctgtt attgatgact ttggaccacg
    12781 tcagatggaa actggagagt tgattatcta tacttcagct gaccctgttt tacaaattgc
    12841 tgcccacgaa gacatcattc ctttggatga attgtaccgt atctgtgaat acgctcgttc
    12901 gatcactctt gagcgtcctg cccttcttgg tcgcatcatt gctcgccctt atgtaggtga
    12961 accaggtaac ttcactcgta cggcaaaccg tcgtgacttg gctgtatctc cattttcccc
    13021 aactgttttg gataaattga atgaggctgg tatcgatact tatgctgtgg gtaaaatcaa
    13081 cgatatcttt aacggtgctg gtatcaacca tgacatgggt cacaacaagt caaatagtca
    13141 tggaattgat acactattga agactatggg acttgctgag tttgaaaaag gattctcatt
    13201 cacaaaccta gttgactttg atgcccttta cggccatcgt cgtaatgctc acggttaccg
    13261 tgattgcttg catgagtttg atgaacgctt acctgaaatt atcgcagcta tgagagagaa
    13321 tgaccttctc ttgattactg cggaccatgg aaatgaccca acgtatgcag gaacggatca
    13381 cactcgggaa tatattccat tgttggccta tagccctgcc tttaaaggaa atggtctcat
    13441 tccagtagga cattttgcag atatttcagc gactgttgcc gataactttg gtgtggaaac
    13501 tgctatgatt ggggaaagtt tcttagataa attggtataa gatgacgcgc tatgctttgc
    13561 tggtgagagg tatcaatgtt ggtggtaaga ataaggtcgt catggcggag cttcgtcaag
    13621 aattgacaaa cttgggactg gaaaaggttg agagctacat caacagtggc aatattttct
    13681 ttacttcgat agattccaaa gcccaattgg ttgaaaagct agagactttc tttgcagtcc
    13741 attatccatt tattcagagc ttttctttac tgagtctaga ggactttgag gcggaacttg
    13801 aaaatctacc agcttggtgg agcagagact tggcacgaaa agattttctc ttttacactg
    13861 agggtttgga tgtggaccaa gtcatcgcga cagttgaaag tttagagctg aaagatgaag
    13921 tgctttattt tggaaaactt gggattttct gggggaaatt ttctgaagaa tcctattcta
    13981 agactgccta tcagaagtac ttgctgaagg tgcctttcta ccgccacatt actattcgta
    14041 atgctaaaac ctttgacaaa attggtcaaa tgctaaaaaa ataataaagg agacacacaa
    14101 tgacattttt aaacaaaatc catgaaactg ctactttcct gaaagaaaag ggaattgcag
    14161 cccctgagtt cggtctaatc cttggatcag gacttggaga attggcagaa gaaatcgaaa
    14221 atccagttgt agtagactat gctgagattc caaactgggg ccgttcaaca gtagtcggtc
    14281 atgctggtaa attggtatat ggtgaactgg caggtcgcaa ggtcttggct cttcaagggc
    14341 gtttccattt ctatgaaggg aatcctctgg aagtggtgac tttcccagtt cgtgtgatga
    14401 aagttcttgg atgtgaaggt gttattgtaa ccaatgcagc tggcggtatc ggatttggtc
    14461 ctggtacctt gatggctatc tcagaccata tcaacatgac ggggcaaaat ccattgatgg
    14521 gtgaaaactt ggatgacttt ggcccacgtt tcccagatat gtctagggcc tacacaccag
    14581 aataccgtgc cactgcccat gaagtggcta aaaaacttaa tatcaagctt gatgaaggtg
    14641 tctatatcgg agttactggt ccgacttatg aaacaccagc agaaattcgt tcctataaga
    14701 cactgggagc agatgcagtt ggtatgtcta cggttcctga agttatcgtg gcagcccact
    14761 ctggcttgaa agttctggga atttcatgta tcactaactt tgcggccggt ttccaagaag
    14821 aactcaatca cgaagaagtt gtagaagtga ctgaacgtgt taaaggtgat ttcaaaggct
    14881 tgcttaaagc gattcttgct gaattgtaag aaaaaagatt taaaagggga agtgcctctg
    14941 ttttttcagg attgactgcc tatccggatt aaagaagaaa cagaggaata ctatgagctt
    15001 cttcctgctc ttataactga aagaagcgga agaataggta tgtctgatct gatagccagc
    15061 attgtgaaag acaagattct aggatactag cattagcttc ctagccaagc agactagtat
    15121 gataaggaga gatgagaatg aattgacttt ctgaatttct cagtcttatc atatatagca
    15181 caatgagatt tcgcttgagt ctgcttgtaa ataaacgaaa agaaagataa gaaataatga
    15241 aaattggtca acgaattatg cgctttggca taaaaaatta agtatcggag ttgtatctgt
    15301 tgtagtcggc tttgatttct agctccagct ggaatttcag ccaatgaagt aaagcaagat
    15361 gtaacatctg aagtggtaat aggtgtgcta gattctaagg aggaattgaa agagtcagaa
    15421 aatgatgctc caaaactaga aactcctctt agagaggagc caagactagc tcctcaaacg
    15481 cttccggaag caagtgaagt tcttgaaaac aaaagggaag agtcaaaagt agagataaca
    15541 gagccagctc aagactcacc tattcttgct cctgtagaag aaactaaaga agaagctgtg
    15601 acagaaaaac caacaaatac tcgttctcta actgcagaag atttggtgaa gatttccaaa
    15661 ggggaattgc atttagaaaa tgatttgatt gatgaatctt tctatggtga aaaagctctt
    15721 gatttggaag gggatgatga ccaggatggc atcaaaaaca aagatggtaa ggattatcta
    15781 ggatataaca gtcatccctt gctagcagac agtgatgggg atggtttggc agatggggaa
    15841 gatgataata agaaagaatg gtatgtcaca gaccgtgatt ctcttctctt tatggagtta
    15901 gcttatcgag acgatgatta tattgagaaa attttatatc ataagaatct tttccctagt
    15961 ctctatcttg accgtcaaga acacaaactc atgcacaatg aattggctcc tttctggaag
    16021 atgaaaaaag cctactatac agatagtggc ttggatgctt tcttatttga gaccaagagc
    16081 gaccttcctt atctcaaaga tggaacggtg tacatgttgg ctattcgtgg aacgcgagtt
    16141 aatgacgcca aggacttgag tgcagatttg gttttattag gtggaaataa accagctcaa
    16201 gcggatgata tccgcaaggt tgttggggaa ttagccaagg atataagtat tactaagttg
    16261 tatatgacag gtcattctct tggatgttac ctagctcaga ttgcagcggt tgaagcttac
    16321 caaaaatatc ctgattttta taaccatgta ttgaggaaag tgacaacttt cagtgctcct
    16381 aaagtgatta cttccagaac tgtttggaat gctaagaatg gtttctggga tgttggtttg
    16441 gaaagtcgta aattagctgt tagtggaaaa attaagcatt atgtggttga taatgacaat
    16501 gttgtgactc ccttgattca taataatcgt gatattgtta catttacagg taattcacgc
    16561 tttaaacacc gttctcgtgg ctattttgaa agtccaatga atgatattcc taactttaat
    16621 attggtaaac aagctacctt ggataaacat ggttatcgtg atccgaaatt ggataaagtg
    16681 cgattcttta agaaacaggc tctgcctcga tcttctagtc aaccaagcgc tgaaccaatg
    16741 gaaaatattg ccttaggaaa acaggttact caaagttcga cagttttcgg aggagatgct
    16801 agaagagctg tggatggcaa agtcgatggt aactatggtc acaattctgt cactcataca
    16861 aacttccaat ctaagccttg gtggcaagta gatttggcta aagaagaaac cattcgccaa
    16921 atcaatattt acaaccgaac agacactgcc caggatagat tggcaaactt tgatgtcatt
    16981 cttttagaca gttctggtaa agaaattgag taaaaacgta taacatctcc taaagatgtg
    17041 tcagcacaaa ttacgattaa ccataaaaaa gtacgctatg ttcggattga gctagaaggc
    17101 tataatgccc tcagtcttgc agaagttgaa gttttccgct ttatagctac gaatgctgaa
    17161 acggcgacac aagtttctaa gccagttcaa ccaatcagtc agactcctgt gaaagataaa
    17221 acattgacaa ttcaacacag tggagcttac attgcccgct actccataac ttgggaagaa
    17281 gttccagtag ataaagatgg aaaccaagtt gttcgtagtc attcttggga aggaaacggt
    17341 tgcaaccaga ctgcaggttt tgtcctcaac ctcccaatca aagaaaatat gagaaatctg
    17401 cgagttaaga ttgagaaaaa gacgggccta ctatggaata gatggcaaac aatctatgaa
    17461 aacagaccaa ttttagctca accccaccgt aaaattaccc attggggtac gacattgaat
    17521 tccaaggtga gtgacgatga tgtcttgtaa tctgatggta caatgacagt tagtttgtct
    17581 agtttataag aaagtactac ctgagcttga atagaactca ggtagctctc tatgaaagaa
    17641 caaaattaat actcaatgaa aatcaaagag caaactagga aactagccgc aggttgctca
    17701 aagcactgct ttgaggttgt agataagact gacgaagtca gtcacatata taatccaagg
    17761 cgacgttgac gtggtttgaa gagattttcg aagagtataa acagaaaggt agagcgcgtg
    17821 ttctaatttg aacacgagta gaaaactttt ctaaaaacaa aaacgaaagg atgggtaaac
    17881 tgtattcgct gaactgaata cgggcgactc tcctctaaat caaaattaag aaagaaagga
    17941 attgaaccac cctaaaagca gtgggaaaaa gatagttggt ctagcgagca tcgctcactg
    18001 cgcccaactc ctattttccc ttcgcttttt gacgggtttg gtatctttct caatataaaa
    18061 tataaaataa agaaaggtag agcgtgtgtt ttgatttgaa cacgagcgga aaactcggaa
    18121 aatagataat ctgactgaaa aatcaggatt tctcgtcagg ttcctaattt tcagtcgttt
    18181 tcttctcgct ctttgtatca taaattatgt ctatccatat tgctgctcag cagggtgaaa
    18241 ttgctgataa aattcttctt cctggggatc ctcttcgtgc taagtttatt gcggagaatt
    18301 tccttggtga tgctgtttgt tttaacgaag tgcgtaacat gtttggttac actggtactt
    18361 acaagggtca ccgtgtatct gtcatgggaa ctgggatggg aatgccatct atttcgattt
    18421 atgcgtgtga gttaatcgta gactacggtg tgaagaaatt gattcgtgtg ggaactgcag
    18481 gttctttgaa tgaagaggtt catgttcgtg aattagtttt ggcgcaggcg gctgcaacca
    18541 actcaaacat cgttcgtaat gactggccac agtacgattt tccacaaatt gctagctttg
    18601 atttgcttga taaagcctac catatcgcca aaaaacttgg tatgactact cacgttggga
    18661 acgttttgtc atctgatgtc ttttactcaa attactttga aaagaatatc gagcttggta
    18721 aatggggagt caaggctgtg gaaatggaag cagcagctct ttactatctt gctgcccaat
    18781 accatgttga tgcgctagct atcatgacca tctctgatag cttggtcaat ccagacgaag
    18841 acacaactgc agaagaacgt caaaatacct tcactgatat gatgaaggtt ggtttggaaa
    18901 ccttgattgc agaataatta tagccaaaaa ggaagccctt tatgaattgt aggacttcct
    18961 tttcttatcc agaaattgat ctagctctct ctgatttcga agaatagtga ctttatgtga
    19021 atattcttgg caaagttttt ggtaattttc tttttgagtt ttgctacgcc catcccaaag
    19081 aatccatctg ataaactccc actcaaagcg ttcagggcaa tctgccgcca tactttctct
    19141 gacttttcca cggtatttaa gataacgctt aaaggctcta aagagacagg tcaatggcga
    19201 aaaattgaga aagatgattt ggtcagcttc ttgcattcgt tcttggtagt agcaccaaga
    19261 ataattacca tcgatgaccc aagctttatg cttggtgaga aagtttttta tctcggttaa
    19321 catccattcg cagtcactgt cttgccaacc aggttgaaat tggagtgtgt ccatgtgcag
    19381 ttttggaatg gagtagtagt tagataactt ttctgctaga gttgacttac cagaaccaga
    19441 atatccgata attgcgattt tcattttcta ccttttccta tttggagaca aaaaaacagc
    19501 ctctatggac tgtttcttat ttagcaagtt tagctgaaag acgagcttta tcgcggcttg
    19561 ctttgttttt gtgaatcaaa cctttagttt ctgctttatc gatagctgag ctagcagcac
    19621 ggaaaagttc ttcagatggg tttgcttcga aagcttttat agcagtacgc atagctgatt
    19681 tttgagctga gttcttttcg ttttgtttaa cgttcaattc agcgcgtttg atagctgatt
    19741 taatgtttgc caatgttctt acctccatat ttactaacta taccattata tatgaaaact
    19801 tacgttttga caagggaaaa ttactttttt aagtaaattt catcgatttc atggttcttg
    19861 cttttatgaa gaatcacttc tgcacgattt ctggttggtt caatataatt ttgcagattt
    19921 gtgagattga tactggtcca gacctgatgg gcaaaggact ccacttcccc aatcggcatc
    19981 tgagtaaaac gataatagta gctatcaggg tcgttttggg ctaggctcag cattttcaag
    20041 aaacggtcca gataccaact ttcaatatca tccactccag catctacata gatggaaaag
    20101 tcaaagaagt cagtgatata gagacgatcg ttttgtggat tttgaaagac attaattccc
    20161 tcaacaatta caaaatcagc agctttgaca ctttgtttct tttcgggtac gatgtcgtaa
    20221 acttcatgag aatagacagg aatatctaca tcttgtccat ttttgatgcg gtccaagaag
    20281 ttgagaagag cttccatatc atagctttca ggaaatcctt tacgatttaa aatcccctgc
    20341 tcaatcaagg tttgattggg atagagaaaa ccatcagttg taaccaactc aaccgtagca
    20401 tctgtaaacg tacgggacag taggatttga agtaggcgac tggttgtgga ttttccaacg
    20461 gcaacactcc cagaaacccc aataataaaa ggttgagatt tactttcacg ttggaggaaa
    20521 attccttttg aaaaggctaa atcttcctta gttcgcttgt aaatctgaat cagatgagcc
    20581 aaggggagat agatatctgt aacgtcttgg agactgattt ggtcattaaa actcttgata
    20641 gattccaatt cttcttctgt caaaggaggt gttgtctttc gatgtaaaga ttgccaagtc
    20701 tggcggctga ttttttcaaa atgtaaaaat tcgttggtca tttgttttcc cctaggtatt
    20761 ttatctatca taccataaaa agctaaaaaa ataaagcggt ttcttgaatg ttgtaagtca
    20821 atgatatata atataagcga tcaatttatt gatgaaatag gagatagatt ctactgattt
    20881 ataagcttat aaagggggct ttttagttca caacttatag gagatgtact atgaaaatct
    20941 taaaacgtta catattggaa ctctgtttta ttttaagttt tgctttacct tttataaaag
    21001 gagccaatgc agataatggt agatgctttg tggaaaccta ttacggtttt acttttttga
    21061 tggaacatgc tattgtaaca gctgtcttta tctgttcgtt cttaattgct gtcttactaa
    21121 aaaacgatgg gcgaaatgga ttgcgacaga gggttatttc ttccgcatgt cactagaaga
    21181 tttgatacga ctttggacaa gtttggaaat cctgacacaa acgtatcagt tgggctttta
    21241 tctaaacatt ttgttaggaa ttttgttgat aataaagtat tttaaggtta agcaatagaa
    21301 ataataatct gcctgattat agatgataaa ctttttgttt ttatctggac tgtgatattt
    21361 atagttctaa atggtttatt atttataagt gttgaaagag attgaagaaa atggcttcgt
    21421 gacttgcttt cttcggtctt tttcgtttta ttatcaattt gtaaacgatt tacaatttga
    21481 gtcaaattat ggtaaaatag tgtcatgagt aaaatgtatt atgcagaaaa tcctgacgct
    21541 gctcacgaca ttcatgagtt gagagtggac ttgttgggac aaaaaatgac ttttttgaca
    21601 gatgcgggtg tttttagcaa gaaaatggtt gactttggaa gtcaactctt gctcaagtgt
    21661 ctgtatgtca accaaggaga gacagtccta gatgtaggct gtggttatgg tccattaggt
    21721 ttgtccttgg tcaaggttta cggagttcag gcgaccatgg ttgatattaa cactcgtgcc
    21781 ttggatttag ctcggagaaa tgctgaaaaa aataatgcaa aagcgacgat tttccagtcc
    21841 aacatctatg aacaagttga aggacatttt gatcatgtca tttccaatcc tcctatccgt
    21901 gcgggcaagc aagtcgttca tgaaatcatt gagaaaagta aagatttctt ggaaactggt
    21961 ggggatttga caatcgtcat ccagaaaaaa caaggggctc caagtgctaa gtccaagatg
    22021 gaggatgtgt ttggtaattg tgaaatcctt aaaaaagaca aaggatacta tatccttaga
    22081 agtgtgaaag aatgagagca gttgatttaa tacaaaaaaa acgagacggt caagaactga
    22141 cttcaagtga aattgaatgg ctggtagaag gctatgtgtc aggaactgtt cctgattatc
    22201 agatgtctgc ctttgctatg gctgtttatt ttaaaggaat gacgactcgt gaaatttctg
    22261 atttaacgat gaatatggtt aagactgggc aagagtttga cctgtcagcc attgatggtg
    22321 tgaaagttga caagcattct actggtggtg tcggcgataa ggtaaccttg attttagctc
    22381 ctcttgttgc tagcttcggt gtgcctgtag caaaaatgag tggtcgtggt cttggccata
    22441 caggcggaac aattgataaa ttggagtcca ttaagggcta tcaagtagaa cgtagtcaag
    22501 aggattttat tcgtcaggtt caggatattg gagtatctgt cattgggcaa tcagaccagc
    22561 tggtcaaagc agataagctt ctctatgccc ttcgtgatgt gaccgcaact gtcgacacga
    22621 ttcctttgat tgcgagttcg gtgatgagca agaaaattgc ggcaggggca gatgctattt
    22681 tgctagacgt gactgtcggt gagggtgcct tcatgaagac ggttgatgag gcgcgtgagt
    22741 tggctcaaac tatggtagat cttggtaagg ttgttggacg gaagacagta gcagtgatta
    22801 cggatatgag ccagcctttg ggacgagcga ttggaaatcg tctggaaatc cttgaagcat
    22861 tggagatttt gcaaggtcaa ggacgtcagg atattaccca ctttatttgt gaattggctc
    22921 aaattatgct tggtttggca aatgttaaca aaactgttga agaagttcgc caacatcttg
    22981 agaatggtca agcactggct aagtttgagg aaatggtgca agcccaaggt ggagacttgg
    23041 aagacctcta tcgtcctgta aatgtagctc atgtggtgga aatccctgct caggaaacgg
    23101 gtgtcatttc agctcttcca gctatggact ttggtcttta tgccatgagg ctgggtgctg
    23161 gtcgtgcagt taagtctgat gccttggact atgaaacagg aattgttttt gaaaagaaga
    23221 ttggagactc cgttcaaaag ggtgaaattg ttgcaaaagt atacacaaat gaaaaaattc
    23281 cacctcaact agttacagat ttccaaaaat gtgttaaaat aagtgatgaa gtgaaaaaaa
    23341 tccgtgaaat tgtagaaatc atctcctaaa tggagggaaa accgaaatga aattaaataa
    23401 atatatagat catacgcttt taaaacaaga tgcaaagaaa aaacaaattg atagtttgtt
    23461 gtctgaggct agagagtatg gctttgccag tgtttgcgtt aatccgacct gggttgaaca
    23521 tgctaaaaaa ggacttgaag gcacagatgt taaggtttgc acagtagtag gtttcccctt
    23581 gggagcaaca acttcaactg tgaaagcttt tgaaacaaaa gaagctatcc aaaatggggc
    23641 tgatgagatt gacatggtaa tcaatgttgg ggctctcaag tcaggtgatt tggccttggt
    23701 tgagtcggat attcgtgcag tagtggaagc aagtggggac aagttagtga aagtcattat
    23761 tgaagcttgc cttctgacag accaagaaaa agttttggct tgccaattag cccaaaaagc
    23821 aggatctgac tttgtcaaaa catctactgg cttttcaact ggtggtgcta cgatagcaga
    23881 tgttagatta atgcgtgaaa cagttggacc tgatatgggt gtcaaggccg ccggtggagc
    23941 tcgttcttat gcagatgctc ttacctttgt cgaagcaggt gcgacccgta tcggaacgtc
    24001 agctggggta gctattttaa aaggagaatt ggcagatggc gactactgag ttgattgaac
    24061 tggcaattga aaccagcaaa catgcctatg tcccctattc tcactttcct atcggagcag
    24121 ttttagtagc caaagaccga agtgtttaca cgggagtgaa tatcgaaaat gctagctatc
    24181 ctttgaccaa ttgcggtgag agaacagcta tttttaaggc tatatctgaa ggccaaagag
    24241 aattttcaga attgattgtc tatggtcaaa ctgaaaaacc gatttcacca tgtggtgctt
    24301 gtcgccaagt aatggtcgaa ttttttgaac aagatttaaa agtgacctta gtcgcaaaag
    24361 ataaatcgac ggtcgagatg acggtcgggg aattacttcc atactctttt acagacttaa
    24421 actagtctga gtcgctctct gagtggcacg gtccttgtgg ccaaccaatc catacttgca
    24481 acatcgttgc acatcttatt taggaggttc agtaatgaac aagaaacaat ggctaggcct
    24541 tggtctagtt gcagtggcag cagttggact tgctgcatgt ggtaaccgct cttctcgtaa
    24601 cgcagcttca tcttctgatg tgaagacaaa agcagcaatc gtcactgata ctggtggtgt
    24661 tgatgacaaa tcattcaacc aatcagcttg ggaaggtttg caggcttggg gtaaagaaca
    24721 caatctttca aaagataacg gtttcactta cttccaatca acaagtgaag ctgactacgc
    24781 taacaacttg caacaagcgg ctggaagtta caacctaatc tttggtgttg gttttgccct
    24841 tcacaatgca gttgaagaag cagctaaaga acacactgac ttgaactatg tcttgattga
    24901 tgatgtgatt aaagaccaaa agaatgttgc gagcgtaact ttcgctgata atgagtcagg
    24961 ttaccttgca ggtgtggctg cagcaaaaac aactaagaca aaacaagttg gttttgtagg
    25021 tggtatcgaa tctgaagtta tctctcgttt tgaagcagga ttcaaggctg gtgttgcgtc
    25081 agtagaccca tctatcaaag tccaagttga ctacgctggt tcatttggtg atgcggctaa
    25141 aggtaaaaca attgcagccg cacaatacgc agccggtgca gatattgttt accaagtagc
    25201 tggtggtaca ggtgcaggtg tctttgcaga ggcaaaatct ctcaacgaaa gccgtcctga
    25261 aaatgaaaaa gtttgggtta tcggtgttga tcgtgaccaa gaagcagaag gtaaatacac
    25321 ttctaaagat ggcaaagaat caaactttgt tcttgtatct actttgaaac aagttggtac
    25381 aactgtaaaa gatatttcta acaaggcaga aaaaggagaa ttccctggcg gtcaagtgat
    25441 cgtttactca ttgaaggata aaggggttga cttggcagta acaaaccttt cagaagaagg
    25501 taaaaaagct gtcgaagatg caaaagctaa aatccttgat ggaagcgtaa aagttcctga
    25561 aaaataatgg atggaagtca tttcttagga agcggccaag ggccgctttt ttaagagttg
    25621 agacaaagtc attttgtctc agtaaagctt gctactagac aaactagcaa gttttattga
    25681 aataaaataa gactctgaaa ggaagagcac atggcacacg aaaatgtcat tgagatgcgt
    25741 gatattacca aggtgtttgg tggatttgtt gccaacgaca aaatcaactt gcacctacga
    25801 aaaggtgaaa ttcatgcact tttaggagaa aatggggctg gtaagtccac gctaatgaac
    25861 atgttagcag gccttcttga accaactagt ggtgaaatcg cggtcaacgg tcaagttgtc
    25921 aatctcgact ccccatctaa agcagctagc ttgggaatcg ggatggttca ccagcacttt
    25981 atgttggttg aagccttcac agtggctgaa aacatcattt taggtagtga attgactaaa
    26041 aatggtgtgc tagatatcgc tggagctagc aaagaaatca aggctctttc tgaacgttat
    26101 ggcttagctg ttgacccttc tgccaaggta gcagatatct cagttggagc ccaacaacgt
    26161 gtagaaattt taaaaacact ttatcggggg gctgatatcc ttatctttga cgaaccaacg
    26221 gctgttttga ctccatcaga aattgatgag ttgatggcta ttatgaaaaa tcttgtcaaa
    26281 gaaggaaaat caattatctt gattacccac aaattggatg aaattcgcgc agtttctgac
    26341 cgtgttacag ttatccgtcg tgggaaatca attgaaaccg ttgaaattgc aggggctacc
    26401 aatgctgatt tggcggaaat gatggtagga cgttctgttt cctttaaaac agagaagcaa
    26461 gcctctaaac caaaagaagt ggttttgtct atcaaagatt tggtggtcaa tgaaaaccgt
    26521 ggtgttccag ctgttaaaaa tctgtccttg gatgttcgtg ctggagagat tgttggtatt
    26581 gcggggattg atggaaatgg tcagtctgaa ctgattcaag ccattacagg tcttcgtaag
    26641 gttgaatctg gtagcattga gctaaaagga gattcaattg taggcttgca cccacgtcag
    26701 attacagaac taagtgttgg gcacgttcca gaagaccgtc accgtgatgg cttgattttg
    26761 gaaatgatga tatctgaaaa tattgccctt caaacctact ataaagaacc acatagtaaa
    26821 aatggaattt tgaattattc aaatattact tcttatgcta aaaagctgat ggaagagttt
    26881 gatgttcgcg ctgccagtga attagttcct gcagctgcac tctcaggagg aaatcaacaa
    26941 aaagcaatta ttgctcgtga aattgatcga gatcctgatc tccttatcgt tagccagcca
    27001 actcgtgggt tggatgtcgg tgccattgag tatatccaca aacgcttgat tgaagagcgt
    27061 gataatggca aggctgtcct tgttgtcagc tttgaattgg atgagatttt aaacgtctca
    27121 gaccgtattg ccgttatcca cgatggtaag attcaaggta ttgtatcacc agaaacaacc
    27181 aataaacaag aacttggtgt cttgatggct ggtggaaact tgggaaagga gaagagtgat
    27241 gtctaaaaaa ttacaacaaa tttcggttcc cttgatttct gtatttctag gaattttact
    27301 cggagccatt gtcatgtgga tcttcggtta tgatgctatt tggggctacg aagaattgtt
    27361 ctatacagcc tttggcagtc tgcgtgggat tggagaaatc ttccgtgcta tgggtcctct
    27421 ggtcttgatt ggtcttggtt ttgcggttgc cagtcgagct ggtttcttta acgtcggact
    27481 tcctggtcag gctttggcag gttggattct cagtggttgg tttgcgctgt cgcatccaga
    27541 tatgccccgt cccttgatga ttctagcaac catcgtgatt gccttgattg ctggtgggat
    27601 tgtcggagcg attccaggta ttcttagggc ctatctaggg acgtcagagg ttattgtaac
    27661 catcatgatg aactacattg tcttgtatgt agggaatgcc tttatccatg ctttccctaa
    27721 agacttcatg caaagtacag attcgaccat tcgtgttggg gctaatgcaa cctatcagac
    27781 accttggttg gctgagttga ctggtaactc acggatgaat attggtattt tctttgccat
    27841 cattgccgtt gcagttattt ggttcatgct caagaaaaca actcttggtt ttgaaatccg
    27901 tgcagttggt cttaatccac atgcttcaga atatgctggt atttctgcca agcggactat
    27961 tatcctatct atgattattt caggtgcctt ggcaggtctt ggtggagctg ttgaaggttt
    28021 gggaaccttc cagaacgtct atgttcaagg ttcgtcatta gctatcggat ttaacggaat
    28081 ggcggttagt ttgcttgcgg ccaactcacc aattggtata ctttttgcag ccttcctatt
    28141 tggcgttctc caagttgggg ctcctggtat gaatgcggcg caggtaccat ctgagcttgt
    28201 cagcattgta acagcgtcta ttatcttctt tgtcagtgtt cattacctta tcgaacgctt
    28261 tgtcaaaccg aaaaaacaag ttaaaggagg taagtaaaga tgtctattat aaccttgctc
    28321 cccctcttgg tgtcttctat gctgatttac tcagcacctc tcatctttac aagtatcggt
    28381 ggtgttttct ctgaacgtgg tggtgtggta aacgttggcc ttgaaggaat tatggttatg
    28441 ggtgcctttt ctggagttgt ctttaacctt gaatttgcag aacaatttgg agcagcaact
    28501 ccatggctat ccttgcttgt agcaggattg gttggtagtg ttttctctat catccacgca
    28561 gcagcgacgg ttcatttccg tgcagaccat gttgtcagcg gtacggtatt gaacttgatg
    28621 gcgcctgcct tggctgtttt cttagttaaa gttctctata acaaaggaca aaccgacaac
    28681 ctaagtcaaa cttttggacg ctttgatttc ccagtcttgg caaatatccc agtgattggt
    28741 gatatcttct tcaagtcaac tagtctactt ggttatctgg cgattgcctt ctcattcctt
    28801 gcttggttta ttctctttaa gactcaattt ggtcttcgtc tccgctctgt cggtgaacat
    28861 cctcaagcag cggataccct gggaatcaac gtctacaaga tgagatattt aggggttatt
    28921 atttcaggtt ttctaggtgg aattggcgga gcgatttatg cgcaatcaat ctcagttaac
    28981 ttctcagtga caactattgt tggacctgga tttatcgccc ttgctgcgat gatctttggg
    29041 aaatggaatc caatcggtgc tatgctttct agtctcttct ttggactttc acaaagtttg
    29101 gctgttatcg gttctcaatt gccgttccta caaggagtgc cagcggttta tcttcaaatt
    29161 gcaccttatg ttttgacaat tcttgtctta gcagccttct ttggaaaagc agtcgcacca
    29221 aaagcagatg gtatcaacta catcaaatca aaataagcat acaaaaaaac gtcagtccaa
    29281 tgactgaact gcaccccaaa agttagacag aaaaaatcta acttttgggg tgtttttatt
    29341 atgaaattga gttgtgatga taaagttcag atctatgaac ttagaaaaca aggatatagc
    29401 ttagagaagc tttcaaataa atttgggata aacaattcta atcttaggta catgattaaa
    29461 ttgattgatc gttacggaat agagttcgtc aaaaaaggga aaaatcgtta ctattctcct
    29521 gatttaaaac aagaaatgat tcataaagtc tgacatgaag gctggactaa agatagagtt
    29581 tctcttgaat actgtctccc aagtcgtacg atacttctta actggctagc acaatacagg
    29641 aaaaacgggt atactattgt tgagaaaaca agagggagag tacctgagag cggagaatgc
    29701 catcctaaaa aagttaagag aactccgatt gaaggaggaa aaagagaaat aagaaagaca
    29761 gaaattgttc aagaattaat gactgagttt tcgttagatc ttcttctaaa atccattaaa
    29821 ctagctcgtt cgacctacta ctatcacttg aaacagctag acaaaacaga taaggaccaa
    29881 gagcttaaag ctgaaattca atccatcttt atcgaacaca agggaaatta tgcttatcgt
    29941 cggatttatt tagaactaag aaatcgtggt tatctggtaa atcataaaag agttcaacac
    30001 ttgatgaagt actcagttta caagctaaaa cgcgacagaa acgaaaatat tcttctcata
    30061 aaggagacgt tggcaagaag gcagagaatc tcattcaagg ccaatttgaa ggctctaaaa
    30121 caatggaaca gtgctacaca gatgtgactg aatttgccat tccagtaagt actcaaaagc
    30181 tttacttatc accagtttta gatggcttta acagcgaaat tatcgcctat aatctttctt
    30241 gttcgcctaa tttagaacaa gtacaaacaa tgttggaaca ggcattcaaa gagaagcact
    30301 atgagaatac gattctccat agtgaccaag gctgtcaata ccaacacgat tctccatagt
    30361 gaccaaggct gtcaatacca acacgattct tatcatcggt tcctagagag taagggaatt
    30421 caagcatcca tgtcacgcaa gggaaacagc caagacaacg gtatgatgga atctttcttt
    30481 ggcattttaa aatccgaaat gttttatggc tatgagaaaa catttaaatc acttaatcaa
    30541 ttggaacaag ccattataga ctatattgat tattacaaca acaagagaat taaggtaaaa
    30601 ctaaaaggac ttagccctgt gcaatacaga actaaatcct tcggataaat taattgtcta
    30661 actgtttggg ggcagtacag aactggcgtt ttatttttta ggatcttgat gagttaggtt
    30721 caatccccaa gggaccaaat tttcagtttt atttttgata cgagctatat tgtccttatg
    30781 acgaatgata atcaaactag caagtgctaa gataatagcg atgaagagag agtcatagtt
    30841 actcaggata aaaccaaaaa gtggaaagag cagaaccccg ataacagccg cgatcgatgc
    30901 tgtgacacta gacagtgaaa tcatactgcc aagatagaga gctccaaaga agataatcgc
    30961 aaggtagaga cagaagatag gcgcaaatcc gaaaatcact ccagcactgg ttgcgacagc
    31021 cttaccacct ttaaatcctg caaagatagg gaaggtatgg ccgataacag ccaaaagtcc
    31081 aaagatgaga ggagaaacgc cttgtagatg aaaaataatc ggaagcagcg ttgctagggt
    31141 tcctttgaaa aagtcaatca caaaggttgc cataccagct ttcttaccta aaatgcggaa
    31201 ggtattggtc gttccagtgt taccagaacc atgctcgcgt agattgattt gaaagaatac
    31261 ttgtccaatc cagagaccag atggaatcga acccagcaga taggctagga ttaataaaac
    31321 tattgtaatc atactcctat tatatcatga attgggaaag aaaagcagag aatctctgct
    31381 gaaattgtca catcggagaa agaaaaattt tgcaaaatcc ttggaaaacc tgtagaatag
    31441 taaagatgaa cgaataggag gttccttgtg tcaaaaaagg aaatcaatat taacaattat
    31501 aatgatgatg ctattcaggt gctagaaggg ttggatgcgg tccgaaaacg tccggggatg
    31561 tatattggat cgaccgatgg cgctggtctt catcacctag tttgggaaat cgttgataat
    31621 gcagtcgatg aagccttgtc tgggtttggt gatcgtatcg atgtaactat caataaagac
    31681 ggtagtctaa cggttcaaga ccatggacgt gggatgccga caggtatgca cgctatggga
    31741 attccaactg ttgaggttat ctttaccatt cttcatgccg gagggaaatt cggtcaaggt
    31801 ggctataaga catcaggtgg acttcacgga gtgggttctt ccgttgttaa cgccctttct
    31861 agctggttag aagttgaaat tacccgtgat ggcgcagttt acaagcaacg tttcgaaaat
    31921 ggtggaaaac ctgtcacgac tttgaagaaa atcggtacag cacccaagtc taaaacaggc
    31981 accaaagtta cttttatgcc tgacgcgact atcttttcta cgacagattt caagtacaat
    32041 accatttcag agcgccttaa tgaatcagcc tttctcttga aaaatgtgac cttgtcttta
    32101 acggacaagc gaacagatga agcgattgag ttccactatg agaatggagt acaagatttt
    32161 gtttcttatc tcaacgaaga taaggaaatc ttgacgccag ttctttactt tgaaggggaa
    32221 gacaatggtt ttcaagtgga agtagccctc cagtacaatg acggattctc agataacatt
    32281 ctatcctttg tcaataacgt tcgcaccaag gacggtggaa cgcacgagac aggactcaag
    32341 tctgccatta ccaaggtcat gaatgactat gcacgtaaaa caggtcttct caaggaaaaa
    32401 gataaaaacc ttgaaggttc agactatcgt gagggactag cggccgttct ttctatctta
    32461 gttcctgaag aacacttgca gtttgaagga cagaccaagg ataaactagg aagcccccta
    32521 gctcgcccag ttgtggatgg aatagtggct gataagttga cctttttcct tatggaaaat
    32581 ggggaattag cttctaacct catccgcaag gctatcaagg cccgtgatgc tcgtgaagca
    32641 gcacgtaagg cgcgtgatga gagccgaaat gggaagaaaa acaagaaaga taagggcttg
    32701 ttgtctggga aattgacccc agcccaatct aagaatcctg ctaagaatga actctatcta
    32761 gttgaggggg actctgccgg tggttctgcc aaacaaggtc gtgaccgcaa gttccaggct
    32821 attctacctc ttcgtggtaa ggttgtcaat acagccaagg ccaagatggc ggatatcctc
    32881 aaaaatgaag agatcaatac catgatttat accattggtg cgggtgttgg agcagacttc
    32941 tctattgaag atgccaacta tgataagatc attatcatga ccgatgcgga taccgacggt
    33001 gcccatatcc agaccttgct cttgacattt ttctaccgtt acatgcgtcc gctagtcgag
    33061 gcaggtcatg tctatattgc cctcccacct ctttacaaga tgtccaaagg taaaggcaag
    33121 aaagaagaag tggcctacgc ttggacggac ggagaactag aagaactccg taaacagttc
    33181 ggtaaaggcg ctaccctcca acgatacaaa ggacttggtg agatgaatgc ggaccagctc
    33241 tgggaaacaa ccatgaaccc agaaacacgt accctcatcc gtgtcacaat tgaagattta
    33301 gcgcgcgccg aacgccgcgt caatgttctc atgggagata aggtagaacc acgccgtaaa
    33361 tggattgaag ataatgtcaa gtttacgcta gaagaagcga cagtgtttta atgaaagaaa
    33421 ataatatgtt agtaaactgg aaattagagt cggatgtgaa tgactatgta aaaaagcagt
    33481 ttgaaaatct tggtttgaaa aaattgcagg attattaatg aagaatcttc tatgagtgct
    33541 tatctcaaag aggcgtttaa gggagcggct aagacacaaa ctaagactaa ttttggaaaa
    33601 ccagattttc atattgaaaa atacaaacag gatagtttgg ttacttatcg taactgaaca
    33661 cgggacgaat tcccgtaaaa tatcttttac tgcataaaaa cctactctac attctttgaa
    33721 aggagttgaa cacgccctag atactgtgtg aaaaagataa attctcttgt gagtttgctt
    33781 acttcaagaa ttttctattt tcacttggta ttttatgggc tttgtatctt atgtctaaca
    33841 ttcaaaacat gtccctggag gacatcatgg gagagcgctt tggtcgctac tccaagtaca
    33901 ttattcaaga ccgggctttg ccagatattc gtgatgggtt gaagccggtt cagcgccgta
    33961 ttctttattc tatgaataag gatagcaata cttttgacaa gagctaccgt aagtcggcca
    34021 agtcagtcgg gaacatcatg gggaatttcc acccacacgg ggattcttct atctatgatg
    34081 ccatggttcg tatgtcacag aactggaaaa atcgtgagat tctagttgaa atgcacggta
    34141 ataacggttc tatggacgga gatcctcctg cggctatgcg ttatactgag gcacgtttgt
    34201 ctgaaattgc aggctacctt cttcaggata tcgagaaaaa gacagttcct tttgcatgga
    34261 actttgacga tacggagaaa gaaccaacgg tcttgccagc agcctttcca aacctcttgg
    34321 tcaatggttc gactgggatt tcggctggtt atgccacaga cattcctccc cataatttag
    34381 ctgaggtcat agatgctgca gtttacatga ttgaccaccc aactgcaaag attgataaac
    34441 tcatggaatt cttgcctgga ccagacttcc ctacaggggc tattattcag ggtcgtgatg
    34501 aaatcaagaa agcttatgag actgggaaag ggcgcgtggt tgttcgttcc aagactgaaa
    34561 ttgaaaagct aaaaggtggt aaggaacaaa tcgttattac tgagattcct tatgaaatca
    34621 ataaggccaa tctagtcaag aaaatcgatg atgttcgtgt taataacaag gtagctggga
    34681 ttgctgaggt tcgtgatgag tctgaccgtg atggtcttcg tatcgctatc gaacttaaga
    34741 aagacgctaa tactgagctt gttctcaact acttatttaa gtacaccgac ctacaaatca
    34801 actacaactt taatatggtg gcgattgaca atttcacacc tcgtcaggtt gggattgttc
    34861 caatcctgtc tagctacatc gctcaccgtc gagaagtgat tttggcgcgt tcacgctttg
    34921 acaaagaaaa ggctgagaaa cgtctccata tcgtcgaagg tttgattcgt gtgatttcga
    34981 ttttggatga agtcattgct cttatccgtg cttctgagaa taaggcggac gccaaggaaa
    35041 acctcaaagt tagctatgat tttacggaag aacagactga ggctatcgta actttgcaac
    35101 tgtaccgttt gaccaatacc gatgtggttg tcttgcagga agaagaagca gagcttcgtg
    35161 agaagattgc tatgctggcg gctattatcg gtgatgaaag gactatgtac aatctcatga
    35221 agaaagaact tcgtgaggtc aagaagaaat ttgcaactcc tcgtttgagt tctttagaag
    35281 acactgcgaa agcaattgag attgatacag ctagtcttat cgctgaggaa gatacctacg
    35341 tcagcgtgac caaggcaggt tacatcaagc gtaccagtcc acgttccttt gcggcttcca
    35401 ccttggaaga aattggcaag cgtgatgatg accgtttgat ttttgttcaa tctgccaaga
    35461 caacccagca cctcttgatg ttcacaagtc ttggaaatgt catctacaga ccaatccatg
    35521 agttggcaga tattcgttgg aaggacatcg gagagcatct gagccaaacc atcacaaact
    35581 ttgaaacgaa tgaagaaatc ctttatgtgg aagtactgga tcagtttgac gatgcgacaa
    35641 cctactttgc agtgactcgc cttggtcaaa tcaaacgggt agagcgaaaa gaattcactc
    35701 catggcggac ctatagatct aagtctgtca agtatgctaa gctcaaagac gatacagatc
    35761 agattgtagc agtggctccg attaaactag atgatgttgt cttggttagt caaaatggtt
    35821 atgccctgcg tttcaatatc gaagaggttc cggttgtcgg tgctaaggca gcaggtgtca
    35881 aggctatgaa tttgaaagaa gatgatgtcc tccaatctgg ctttatctgt aatacttcgt
    35941 ccttctacct cttgacccag cgtggaagct tgaaacgtgt ttccattgag gaaattctag
    36001 caaccagccg tgccaaacga ggattacaag tcttgcgtga gttgaaaaac aaaccgcatc
    36061 gtgtcttctt ggcaggagca gttgcagagc aaggatttgt tggcgatttc ttcagtacgg
    36121 aagtggatgt gaacgaccaa actctacttg tccaatccaa taaaggaaca atctatgaaa
    36181 gccgattgca agacttgaac ttgtcagaac gcactagcaa tggaagcttc atttctgaca
    36241 cgatttcaga tgaagaagtt tttgacgctt atcttcagga agtagttact gaagataaat
    36301 aagtgaaatg aagaatcagt tctaagagct ggtttttatt ggagaaattt tctgaaaatt
    36361 acaaaatata cttgctattt tagaaaaata gtgtagaata taagaaatag gtttttagaa
    36421 taaggagtgg aatatgacag taacgattga ttgggaaaac ctcggttttt cctatatgaa
    36481 attaccttat cgctatcttg ctcatttcaa aaatggacaa tgggatcaag gagagcttac
    36541 agaggatgca actttgcata tttcagagtc ttctccaagt cttcactatg gacaacaagc
    36601 atttgaaggt ttgaaagctt atcgtactaa ggatggcagt gttcaactgt tccgtcctga
    36661 tgaaaatgct aaacgcctgc aacgtacatg tgaccgtctc ttgatgccac aagttccgac
    36721 agacatgttt gtagaagctt gtaaagcagt tgtccgtgcg aatgaagaat acgtaccacc
    36781 atacggaata ggtggaactt tatatcttcg ccctcttttg attggtgtcg gagatattat
    36841 cggggtaaaa ccggcagaag agtacatttt caccatcttt gctatgccag ttggaaatta
    36901 ctttaaaggt ggtttggtcc caaccaactt cttgattcag gatgagtacg accgtgcagc
    36961 accaaatggt acaggtgcgg ctaaggttgg tggaaactat gctgcaagtc tcttaccagg
    37021 aaaaatggcc aagtcacgcc atttctcaga tgttatctat ctggacccat caactcatac
    37081 aaagattgaa gaagtcggat cagctaattt ctttggaatt acagctgata atgaatttgt
    37141 aacaccattg agtccatcta tcttgccatc tattaccaag tattccttgc tttatttggc
    37201 agaacatcgc ttgggattaa ctcctattga gggtgatgtt ccaattgata atcttgaccg
    37261 ttttgtagag gcaggtgcct gtggtacagc agcggttatt tctccaattg gaggtattca
    37321 acatggtgat gatttccatg tattctatag tgaaacagaa gtaggtcctg tgacgcgtaa
    37381 attatataat gaattgacgg gtattcagtt tggcgatatt gaagcgccag aaggttggat
    37441 tgtaaaagta gattaaaata aaccaaagga gattttttat gaaatagaaa aagtggctct
    37501 taacagcagg agtggtcctg agcacgtcag ctattttagt ggcttgtgga aaaactgata
    37561 aagaagcaga tgcaccgaca acattttctt atgtctatgc agtagatcca gcatcattgg
    37621 gctacagtat agcgactcga acatcgagga cagacgttat tggaaatgtt attgatggtt
    37681 tgatggaaaa tgataaatac ggcaatgttg ctccttctca aaaagactat gatttgaaca
    37741 gtacaggatg ggctccaagc tatcaagatc cagcgtctta cttgaatatt atggatccaa
    37801 aatctggttc tgccatgaaa caccttggca ttacgaaagg aaaagataag gatgttgtag
    37861 ctaaacctgg tttggataaa tataagaaat tgttagaaga tgctgtttct gagaccactg
    37921 acctagagaa gagatatgaa aaatatgcca aagctcaagc ttggtcgaca gatagttcat
    37981 tattgatgcc aacagcttca tctggtggtt ctccagttgt aagtaacgta gtaccattct
    38041 caaaaccata ctcacaagtt ggtattaagg gggaaccata tatctttaaa ggaatgaaat
    38101 tgcaaaaaga tattgttaca acaaaagaat ataacgaggt ttttaaaaaa tggcaaaaag
    38161 aaaaattgga atccaatagc aaataccaaa aagaactaga aaaatacatt aaataaggaa
    38221 tggtattgat cttgataaaa tttttaaaat actgtcattt tgaatataaa ggagtttgat
    38281 atggagtgga ttagattaat aggaatagca atcattgttg tgggttttat tttaaaattt
    38341 gatacaattg caacagtagt cttagctggt ttggttacag ctttagtttc aggtgtttct
    38401 ctcgttgaat ttttggagat tttgggaaaa gaatttagca atcagcgagt gctcacgatt
    38461 tttatggtta ccttgcctct tgtggggctg tcagaaacct ttggactcaa gcaacgatca
    38521 atcgatttga ttcgaaagat taaaggtctg acagttggaa acttctatac agtttatttc
    38581 tttattcgag agttagctgg tttcttttca attcgtctag gaggacaccc tcagtttgtc
    38641 agacctttgg ttcaacctat gggagaagca gctgcagagt ctcaattagg tagaaagtta
    38701 acagaggttg aagatgagac aataaaagcg cgtgcggctg cgaatgaaaa ttttggaaat
    38761 ttctttgctc aaaatacgtt tgtaggtgct gggggagtcc tcttgatagg gggaacatta
    38821 gatcagttag gctatgaaag caattatgca gggattgctt ctacatctat tattgttgct
    38881 gttataacac ttattgtagt ggggatttac aattatttat ttgataaaaa attgatatca
    38941 aaaaagacta ggggaggaga acaaaaatga cagagttggc aaagcaacta ttagagttga
    39001 cctatattgt gattggttgt caatttctcc atacagccta ttgtagttat aaagataaaa
    39061 caaacccagt tcgacttggg acatctgcat tttggactct attgtctatt acgtttatag
    39121 gtggttccta tatgccaaat atgagtattg gtattattgt aatcctatta tcgctgttaa
    39181 cattgtttaa gcaagtccgt atcggaacct tgccatcctt agatgaaatg aaagccaata
    39241 ttgaatctaa caggttgaaa aataaaattt ttattccagt tatgctgatg gcaatacttg
    39301 cgttggtctt agcgcaaatg attccagaat ttagcaagat ttcgattagc cttgccgcct
    39361 tgtttgctac aatttctgtt cttgtgatta ccaatagtca ccctaagagt ctgttatcag
    39421 aaaataatcg aatgactcag caagtttcaa caagtgggat tgttcctcaa ttattagggg
    39481 ctttgggggc tatttttact gtagcaggtg ttggtgatgt tatctctcat ctgattagcg
    39541 gtattgttcc ttcagatagt cgctttatag gagttttggc ttatgttctt ggaatggttc
    39601 tattcacaat gattatggga aatgcttttg cagcattcac cgttattaca gcaggtgttg
    39661 gagttccctt tgtatttgct ctgggagcta atccaattgt ggctggtgct cttgccatga
    39721 cagcaggtta ttgtgggacc ttattgaccc caatggctgc taattttaac gctctaccag
    39781 cagcattgat ggatatgaaa gatcagaatg gcgttataaa ggctcaagca ggtgttgctc
    39841 tagtaatgat tgttattcac atattcttaa tgtactttct cgcattttag taaaggaaaa
    39901 taaaatgaaa atattggtta caggttttaa tccttttgga ggtgaaaaga ttaatccagc
    39961 tttggaggct gtaaaattat taccatctga gattaatggg gctgaagttc gctgggtaga
    40021 aattccaacg gttttttata agtcgtcaga agttttagag gcagaaatat tacgatatca
    40081 accagatgct gtactttgta ttggacaagc aggcggcagg accggcttaa cacctgaacg
    40141 agtggctatt aatcaagatg atgctcgcat acctgataac gaaggcaatc aaccaattga
    40201 tacaccgatt cgtattgatg gagcatcggc ctattttagt agtttaccta tcaaagcgat
    40261 ggtacaagct atcaaaaaac agggacttcc ggcagttgta tccaatagtg caggaacctt
    40321 tgtttgcaat catttgatgt accaagctct ttatttagtg gataaaaaat tccctaatat
    40381 gagagcaggt ttcatgcata ttccatatat gatggaacaa gtagtaaata agccgaatac
    40441 tgcaggaatg agtctatgtg atattgtaag aggcatagag gtagctattg aagctattgt
    40501 agactacaaa gataaggatt tgcagttagt aggcggtgag actcactgat aacctaaaaa
    40561 ggatagtcaa ttatgcttgt ttactaacta ttaactatgc taaatcaatt gaggttgttt
    40621 acataaaact ctatatcaga gaagcctgat atagagtttt ttcttgctag ttttaggatt
    40681 ttcttgtaaa atagaaaaag tgaagagagg tatgaaatga gcaagaaaga taaaaaaatc
    40741 gaaattcaag tagcggatgc caaagttaat gttggtaaag acagttttga aggttataca
    40801 ttgactatcg gtaaaaaagt tatcggagaa attgccgaat tagacggaca atttgccatt
    40861 ataaagaatg ggaatgtcga tagtttttat aaaaaattgg aaaaagctgt ggaaattttg
    40921 attgaaaatt ataatttagc aaaataagtc ttgttttttt gaaattttca tgatataata
    40981 gtccatgttg attgtaggag agatagcgaa gaggctaaac gcggcggact gtaaatccgc
    41041 tccttcgggt tcgggggttc gaatccctct ctctccattt cattaatggg gtatagccaa
    41101 gcggtaaggc aagggacttt gactccctca tgcgttggtt cgaatccagc taccccagtt
    41161 cttaggtaat aatcaagata gaaagcaaaa tatcttaggg tattttattt ttataattga
    41221 aagacgtgaa tgatatgaac atgtccttgc gggtgcttag gaaaaaaatt ataagtatgt
    41281 caagtttaag aaaaacttga ttgttggagg attttttaga tgaacgaatt tgaagatttg
    41341 ctaaatagcg ttagtcaagt tgagactggt gatgttgtta gtgctgaagt attgacagtt
    41401 gatgcgactc aagctaacgt tgcaatctct ggaactggtg ttgaaggtgt cttgactctt
    41461 cgcgaattga caaacgatcg tgatgcagat atcaatgact ttgttaaagt aggagaagta
    41521 ttggatgttc ttgtacttcg tcaagtagtt ggtaaagata ctgatacagt tacatacctt
    41581 gtatctaaaa aacgccttga agctcgcaaa gcatgggaca aacttgttgg tcgcgaagaa
    41641 gaagttgtta ctgttaaagg aacgcgtgcc gttaaaggtg gactttcagt agaatttgaa
    41701 ggtgttcgtg gatttatccc agcttcaatg ttggatactc gtttcgtacg taacgctgag
    41761 cgttttgtag gtcaagaatt tgatactaaa atcaaagaag ttaacgctaa agaaaaccgc
    41821 ttcatccttt cacgtcgtga agttgttgaa gcagctactg cagcagctcg cgctgaagta
    41881 ttcggtaaat tggctgttgg tgatgttgta actggtaaag ttgctcgtat cacaagcttc
    41941 ggcgctttca tcgaccttgg tggtgttgac ggattggttc acttgactga attgtcacat
    42001 gaacgtaacg tatcaccaaa atcagttgta actgttggtg aagaaattga agtgaaaatc
    42061 cttgatctta acgaagaaga aggacgtgta tcactttcac ttaaagcaac agtaccagga
    42121 ccatgggatg gcgttgagca aaaattggct aaaggtgatg tagtagaagg aacagttaaa
    42181 cgtttgactg acttcggtgc atttgttgaa gtattgccag gtatcgatgg acttgttcac
    42241 gtatcacaaa tttcacacaa acggattgaa aatccaaaag aagctcttaa agttggtcaa
    42301 gaagttcaag ttaaagttct tgaagttaac gcagatgcag aacgcgtgtc actttctatt
    42361 aaagctcttg aagaacgtcc agcccaagaa gaaggacaaa aagaagaaaa acgtgctgct
    42421 cgtccacgtc gtccaagacg tcaagaaaag cgtgatttcg aacttccaga aacacaaaca
    42481 ggattttcaa tggctgattt gtttggtgat atcgaacttt aatcaaattg aaaattcaca
    42541 aaatcctttg tttactaaac aagggatttt tctggctctt tgtcaactgt agtgggttga
    42601 agtcagctaa gcttgagaaa ggacaaattt cgtcctttct tttttgatgt tcaaagcgat
    42661 aaaaatccgt tttttgaagt tttcaaagtt tcgaaaacca aaggcattgc gcttgataag
    42721 tttgatgaga ttattggtcg cttccagttt ggcattagaa tagtgtagtt gaagggcgtt
    42781 gataatcttt tctttatctt tgaggaaggt tttaaagaca gtctgaaaaa taggatgaga
    42841 ctgcttaaga ttgtcctcaa taagtccgaa aaatttctct ggttccttat tctggaagtg
    42901 aaacagcaag agctgataga gctgatagtg gtgtttcaag tcttgtgaat agctcaaaag
    42961 cttgtctaaa atctctttat tggttaaatg catacgaaaa gtaggacgat aaaatcgctt
    43021 atcactcagt ttacggctat cctgttgtat gagcttccag tagcgcttga tagccttgta
    43081 ttcatgggat ttttgatgaa actgattcat gatttgaaca cgcacacgac tcatagcacg
    43141 gctaagatgt tgtacaatgt gaaagcgatc aagaacgatt ttagcattcg ggagtgaaac
    43201 agtctgggag actgtttcag cctgagccta gaaatttgaa agcgaagctg tttagccaag
    43261 tcatagtaag gactaaacat atccatagta atgattttga cgcgacatcg gacggctcta
    43321 tcatatttaa gaaagtgatc tcggatgaca gcttgtgttc tgccttcaag aacagtgatg
    43381 atattgagat tgttaaaatc ttgcgcaata aagctcatct ccatctcccg attgaaacag
    43441 tcactccccg gactgtttca acgtcccagg acataatctc aggaagacgc gaaaaatcat
    43501 gctcaaagtg agaatcattg agctttcgaa tgacagttga agttgaaatg gccagctgat
    43561 gagcaatatc ggtcatagaa atcttctcaa tcaacttttg cgcaattttt tggttgataa
    43621 tacgaggaat ttgatgattc ttcttgacga tagaagtttc agcgaccatc attttagaac
    43681 aatgatagca cttgaaacga cgctttctaa ggagaattct agtaggcata ccagtcgttt
    43741 caagataagg aattttagaa ggtttttgaa agtcatattt cttcatttga cttccgcact
    43801 caggacaaga tggagcttca tagtccagtt tggcgatgat ttccttgtgt gtatccttat
    43861 tgacgatgtc taaaatctgg atattagggt ctttaatgtc tagtaatttt gtgataaaat
    43921 gtaattattc catatgattc tttctaatga gttgttttgt cgcttttcat tataggtcat
    43981 atgggacttt ttttctacac aaaaataggc tccataatat ccatagggga tttacccact
    44041 acaaatatta tagagcccaa aatcctttgt ttactaaaca agggattttt cttttgtctc
    44101 tgctcctttt ttgatataat agttctatgt taaaatcaga aaaacaatca cgttatcaaa
    44161 tgttaaatga agaattgtcc ttcctattgg aaggcgaaac caatgttttg gctaatcttt
    44221 ccaacgccag tgctctcata aaatcacgtt ttcctaatac cgtatttgca ggcttttatt
    44281 tgttcgatgg aaaggaattg gttttaggcc ccttccaagg aggtgtttcc tgcatccgta
    44341 ttgcactagg caagggtgtt tgtggtgagg cagctcactt tcaggaaact gttattgttg
    44401 gagatgtgac gacctatctc aactatattt cttgtgatag tctagctaaa agtgaaattg
    44461 tggtgccgat gatgaagaat ggtcagttac ttggagttct ggatctggat tcttcagaga
    44521 ttgaggatta cgatgctatg gatcgagatt atttggaaca atttgtcgct attttgcttg
    44581 aaaagacagc atgggacttt acgatgtttg aggaaaaatc ttaatgtatc aagcacttta
    44641 tcgaaaatat agaagtcaaa acttctccca gttagttggt caagaagttg tggctaagac
    44701 tcttaaacaa gcggtggagc aagagaaaat aagtcacgct tatctttttt ctggtcctcg
    44761 tggaacggga aaaaccagtg ttgctaaaat ctttgccaag gctatgaact gtcccaatca
    44821 agtgggtggc gaaccttgca ataactgcta tatttgtcaa gcagtgacgg acggtagttt
    44881 agaagatgtc attgaaatgg atgcagcttc taataatggg gtagatgaaa ttcgcgaaat
    44941 tcgtgataaa tctacctatg cgcctagcct tgctcgttat aaggtttata tcatagatga
    45001 ggttcacatg ctgtctacag gggcttttaa tgccctccta aagacgctgg aagaaccaac
    45061 acagaatgta gtctttattt tggccactac tgaattgcac aagattcctg ctactattct
    45121 atcccgtgtg caacgttttg agtttaaatc aattaagaca caggatatta aggaacatat
    45181 tcactatatc ttagaaaaag aaaatatcag ttctgaacca gaggctgtgg aaatcattgc
    45241 cagacgggcg gaaggtggaa tgcgggacgc cttgtctatt ttggatcaag ccctgagttt
    45301 gacacaggga aatgagctga cgactgctat ctctgaagaa attactggca ccattagcct
    45361 atcagccttg gatgattatg tggcggcctt gtctcaacag gatgttccca aagctttgtc
    45421 ttgcttgaat cttctttttg acaatggtaa gagcatgact cgttttgtga ccgatctttt
    45481 gcactattta agagacttgt taattgttca aacaggggga gaaaatactc atcatagttc
    45541 agtctttgta gaaaatttgg cacttcctca aaaaaatctg tttgaaatga ttcgcttagc
    45601 aacagtgaat ttagcagata ttaagtctag tttgcagccc aagatttatg ctgaaatgat
    45661 gaccgtctgt ttggcggaaa tcaagcccga accagctcta tcaggagcgg ttgaaaatga
    45721 aattgctacg ctgagacagg aagttgcccg tctcaaacaa gagctttcta atgcaggtgc
    45781 ggttcctaaa caagttgcac cagctcctag tcgaccagct acgggcaaaa cagtctatcg
    45841 tgtcgatcgc aataaagtgc aatctatctt acaagaggcc gtcgaaaatc ctgatttagc
    45901 acgtcaaaat ctaattcgtt tgcagaatgc ctggggagag gtaattgaaa gtctaggtgg
    45961 gccggacaag gctctgctag ttggttctca accggttgct gccaatgaac accatgctat
    46021 tcttgctttt gagtctaact tcaatgctgg tcaaactatg aaacgagaca atctcaatac
    46081 catgtttggt aatatcctca gtcaggcggc aggtttttca cctgagattt tagctatttc
    46141 catggaggaa tggaaagaag ttcgcgcagc cttttcagcc aaagccaaat cttctcaaac
    46201 tgaaaaagaa gtagaagaaa gcctgattcc agaaggattt gaatttttgg ctgataaagt
    46261 gaaggtagag gaagactaaa gaaagatttc atgatacaat aagtttatga ataaacaaca
    46321 atttattatt atggcgctat ttacagctgc tgagacctat tttttcaatg aagcctggat
    46381 gactggccgc tatattatgg cagccttttg ggcaatttta ctctttagaa atttccgagt
    46441 cagttatgtg atgggtaaaa ttgttgatgt catcgatcag cattttaata ggaaagacta
    46501 gccctcagct tccagacaaa atcaaagcct tttaggcttt tttttgttat actagaaaag
    46561 tatatttata gaatttttgc tctatttctg gggaaatcag acgtttttct agtaagtact
    46621 gtaaaagttt tgaaaaagaa aggaactatc atgtcagtaa tagagatcaa agatcttcac
    46681 gttgagattg aaggaaaaga aattttaaaa ggggttaacc tgaccctgaa aacaggagaa
    46741 attgccgcta tcatgggacc aaatggtaca ggtaaatcga ctctttctgc cgctatcatg
    46801 ggaaatccaa actatgaagt aactaaaggt gaagttttgt ttgatggcgt aaacatcctt
    46861 gagttggaag tggatgagcg tgcgcgtatg ggacttttcc ttgctatgca atacccatca
    46921 gaaatccctg gaattaccaa tgctgagttt cttcgtgccg ctatgaatgc gggtaaagaa
    46981 gatgatgaga agatttcagt tcgtgagttt attactaagc tagatgaaaa aatggaattg
    47041 ctcaacatga aagaagaaat ggcagagcgt tacctcaacg aaggcttctc tggtggtgag
    47101 aaaaaacgca atgaaattct tcaacttttg atgttggagc caacatttgc tcttttggac
    47161 gagattgact caggtcttga tattgacgct cttaaagttg tgtctaaagg tgtcaatgcc
    47221 atgcgtggtg aaggttttgg tgctatgatc atcactcact accaacgtct tttgaactat
    47281 atcacacctg atgtggtaca cgtgatgatg gaaggtcgtg ttgtcctttc tggtggtcca
    47341 gaattggctg cgcgtttgga acgtgaagga tacgcaaaac tagctgaaga acttggctac
    47401 gactacaagg aagaattgta attccctcgt atcttttagg agaagtaaat gactagagaa
    47461 aatattaaac ttttttcaga aatgcacgct gaaccaagct ggttggctga tctccgtcaa
    47521 aaagcttttg acaagattga gactttggaa ttaccagtta ttgagcgtgt caaattccac
    47581 cgttggaatc tgggtgatgg aacgattaca gaaaatgagc catcagcaaa tgttccagat
    47641 ttcacagctt tagatcatca cttgaagttg gtgcaagtag gaactcaaac tgttttcgaa
    47701 caaactccag ttgagttagc tgaacagggt gttgtcttca cagactttca ctcagcttta
    47761 gaagaaattc cagagctgat cgaagaattc ttcatgtcat ctgttaagta tgatgatgac
    47821 aagttggcgg cttaccacac agcttacttt aacagtggtg ctgtactcta tattccagat
    47881 aacgtagaaa tcacagagcc aattgaagga attttctacc aagatagcga tagcaatgtg
    47941 ccgtttaaca agcatattat gattatcgct ggtaaaaatt ctaagattag ttatctggag
    48001 cgtttagagt cacgcggtga aggaagtgac aaagtaactg ccaatatcac agtggaagtg
    48061 attgcacgtt ctggtgcgca agtcaagttt gctgctatcg accgtctagg tgaaaacgtc
    48121 actgcctaca ttagccgtcg tggtaaatta ggcaacgatg caagtattga ctgggctatc
    48181 ggtgtcatga acgaaggaaa tgtcgttgct gattttgata gtgacttgat tggtaatggt
    48241 agccatgctg acctcaaggt tgtagctctt tcaagtggtc gtcaggtaca agggattgat
    48301 actcgtgtaa ctaactatgg ctgcaactct atcggaaata tcctacaaca tggggttatc
    48361 cttgaaaaag caactttgac tttcaatggt atcggccaca tcatcaaggg tgctaaggga
    48421 gcagatgcgc aacaagagag ccgtgttctc atgctttcag accaagcgcg ttcagatgct
    48481 aacccaattc ttttgattga tgaaaatgat gtcactgcag gacacgcagc gtctatcgga
    48541 caagttgatc cagaagacat gtattacctc atgagtcgtg gattggataa ggcaactgca
    48601 gagcgtttgg ttgttcgtgg tttccttgga tctgttatcg tggagattcc agtcaaggaa
    48661 gttcgtgatg aaatgattgc aactatcgaa gagaaattgt caaaacgcta aggggaagcc
    48721 tatgttagat gtagaagcga ttcgcaagga ttttccaatt ttagatcaga ttgtcaatga
    48781 tgaacctctg gtctatctgg acaatgctgc gacgacacaa aaaccactag tagttctgaa
    48841 agctattaac agttactatg agcaggacaa tgccaatgtt caccgtggtg tccatacctt
    48901 agcggaacga gcgacagctt cttatgaagc tgctcgtgaa accattcgta agtttattaa
    48961 tgcaggctct acaaaggaag ttctctttac cagaggaacg acaaccagcc ttaactgggt
    49021 ggcacgcttt gctgaggaaa ttctcgctga gggagaccgg gtcttgattt cagtaatgga
    49081 acaccattct aatatcattc catggcagga agcttgtcga aagactggag cagagcttgt
    49141 ctatgtctat cttaaagacg gtgccttgga tatggaggat ttgcgagcta aattgactga
    49201 taaggttaaa tttgtttccc tagctcatgc ctccaatgtt cttggtgtgg tcaatccgat
    49261 caaggaaatc actcaattag cccaccaagt tggggcaatt atggtagtgg atggtgctca
    49321 atctacacct catatgaaga ttgatgtcca ggacttggat ctggactttt tcgccttttc
    49381 gggtcacaag atggctggtc cgactggtat cggtgtcctt tacggcaaag aaaagtatct
    49441 tgagcaaatg tctccagtag aatttggcgg cgagatgatt gattttgtct acgagcaatt
    49501 tgctagttgg aaggaattgc cttggaaatt tgaggctgga acgccaaata tggcaggagc
    49561 tattggactt gcgactgcag ttgattatct ggaaaagatt ggtatggatg ccgttgaagc
    49621 tcatgaacag gaattgattg cgtacgtcta tccaaaactg caggcaattg agggattgac
    49681 catttacggt tctcaggatt tggctcaacg ttcgggtgtt attgccttta acctaggtga
    49741 tctccatcct cacgatcttg cgacggctct ggattatgaa ggagtggctg ttcgtgctgg
    49801 tcaccattgt gcgcaaccct tgcttcagta tttggaagtc ccagcaacag ctcgtgcaag
    49861 tttttatatc tacaatacca aggcagattg cgacaaacta gtcgatgccc tacaaaagac
    49921 aaaggagttt ttcaatggca ctttctaaac tagatagcct ttatatggca gtggtagcag
    49981 accattcgaa aaatccacat caccaaggga agttagaaga tgctgagcaa accagtctca
    50041 acaatccgac ttgtggggat gtcatcaacc tctctgtcaa gtttgatgca gaggaccgtt
    50101 tggaagatat tgcttttcta aattcaggat gcacgatttc aactgcttct gctagtatga
    50161 tgacagatgc cgttttagga aaaaccaaac aagaaatttt agaactggcg actatttttt
    50221 ctgaaatggt tcaagggcaa aaagatgagc gtcaaggcca acttggagac gcggcattct
    50281 tgtcaggtgt tgccaaattc cctcaaagaa tcaagtgtgc aaccctagct tggaatgccc
    50341 ttaagaaaac aattgaaaat caagaaaaac agtaagacaa gtttcttttg tcttatgaat
    50401 tattagaaat gaagaaagaa aggatactat ggctgaagaa agagtagaac caaaaccaat
    50461 tgaccttggt gaatataaat ttggtttcca tgacgatgta gagcctgtct tatcgacagg
    50521 aaaaggactc aacgaaggtg ttattcgtga attatctgct gctaagggtg agcctgagtg
    50581 gatgttggag ttccgtttga agtcttatga aaccttcaaa aaaatgccca tgcaaacttg
    50641 gggagcagac ttgtcagaga ttgactttga tgacttaatc tactaccaaa aaccatctga
    50701 caaaccagcc cgttcttggg atgatgtacc tgaaaagatt aaagaaacct ttgaacgtat
    50761 cgggattcca gaagctgaac gtgcttattt agcaggggct tctgcccagt acgagtcaga
    50821 agtggtttac cacaacatga aggaagagtt ccaaaaatta ggtattatct ttacagatac
    50881 agattccgca ctcaaggaat acccagactt atttaaacaa tactttgcga agttggtacc
    50941 gccgacagat aacaagttgg cagccctcaa ctcagcagta tggtcgggtg gaacttttat
    51001 ctacgtgcca aaaggtgtca aggtagatat tccacttcaa acttatttcc gtatcaataa
    51061 cgaaaatata ggtcagttcg aacgtacctt gattatcgtt gatgagggag caagcgtcca
    51121 ctacgtagaa ggatgtacag caccaacata ttcaagcaat agcttacacg ctgccattgt
    51181 agaaattttt gctttggacg gagcttatat gcgttataca actatccaaa actggtctga
    51241 taacgtctat aacttggtaa caaagcgtgc taaggctcaa aaggatgcta ctgttgagtg
    51301 gattgatgga aacttgggtg ccaaaacgac tatgaaatat ccatctgttt accttgatgg
    51361 agaaggagcg cgtggtacca tgctctctat cgcctttgct aatgcagggc aacaccaaga
    51421 cacgggtgct aagatgattc acaatgctcc acataccagc tcgtctattg tgtctaaatc
    51481 catcgctaaa ggtggaggaa aggttgacta ccgtggacaa gtcaccttta acaagaactc
    51541 taagaaatct gtttcccaca ttgaatgtga taccattatc atggatgact tgtcagcatc
    51601 agatactatt ccatttaatg aaattcacaa ctcgcaagtg gctttggaac acgaagccaa
    51661 agtatctaag atttcagaag agcaattgta ttatctcatg agccgtggat tgtcagaatc
    51721 tgaggcaact gaaatgattg tcatgggatt tgtagaaccc tttacaaaag aacttccaat
    51781 ggaatacgca gttgagctga accgcttgat tagctatgaa atggagggat cagttggata
    51841 aaatttgatt ttatactctt cgaaaatctc ttcaagccac gtcagcatcg ccttaccgta
    51901 tgtatggtta ctgacttcgt cagtttcatc tacaacctca aaacagtgtt ttgagcaacc
    51961 tgcggctagc ttcctagttt gttctttgat tttgagtatt agatttactc aaaatcaagg
    52021 attttgaaga tgaacttgta tcaaaaaatc gcggtttaaa atcgcgattt tttataattt
    52081 ctcgttaaca aagcggacaa actgattcca ccaaactttt aagaagaagg ctttttcaat
    52141 tttcttgtct gctaccattt cgaaactagg gcgctctgtg gtgatgtaac cttgaccaat
    52201 caagtccttg tcttcataag tcaaatggcc aaccactgtt ccagcttcaa gtggtgctgg
    52261 gattgctttg gaatcaggtg tgaattgaac agattgggaa gattgattcc caatctgttc
    52321 gattagatag atatcctctg gagccactgc agttactgta tcttcttttc catcttgtac
    52381 aggggctttg ctatcttgat aggcatcgcc ttgttgaacg attttgcgaa gtgtaaatgt
    52441 agaagaaata taatccatta gggaagatgt agctgtaaat cgagcgtaag gattattgtc
    52501 ttgatgatct gcatttaaaa caactgtgat gactctcatg cctttttcga cagtagtacc
    52561 aacaaaagac tctccagcct tatctgttgt tcctgttttt agcccatcaa aaccaccacg
    52621 gtaagcaggc ataccttcta acatgtagtt ggttgaagtg attgtcatcc cagcaaaagt
    52681 agaagaaggt tttttagtga tttctaagac ttgtgggtat tttttgatga ggttgcgagc
    52741 aacgatagcg acatcataag cactaagctt attttcctca tcttttttag aacctgggta
    52801 aatgttatcc cctagagttt cattgttaag acctgtcgta ttgacaacag tggcatcctg
    52861 aattccccat tccaagagtt ttgcccgcat catatcgacg aaatcttttt ctgagccagc
    52921 aattttctca gctagggcaa tagcggcgct gttggcacta gataccagag ttgcttcaag
    52981 caactcttcg acagtataat tacgggcctc cataggaata ttactggctt cagaatttgt
    53041 cgtcaattga taaggataat cagaaatatc tacaggagtg gagagggtaa tacttccgtt
    53101 ttccaaagct tcatagacca gataaacagt aatcaatttt gttatggaag caatttcgac
    53161 aggttgcgtt gcatccttct catagagaat tttaccagta tttgcctcaa cagcaatcgc
    53221 atgtttagcg gcaatggtaa aatcttgagc aacagcagta gaagcacccc ctaaaagaga
    53281 gacagttaac aaagttaaaa atattttttt catagtagtc ttattctatc ataaagaaaa
    53341 aaaatattct tgctttaata attcatctgt taagcttttt gaaaatatgg taaaataaag
    53401 tgagggaggt aactcatgtt tcgtagaaat aaattatttt tttggaccac agaaatttta
    53461 ctcttaacca tcatctttta cctatggaga cagatggggt ctttgattaa cccttttgtt
    53521 agcgtgctta atacaattat gattccattt ttattaggag gctttcttta ttatttgaca
    53581 aaccctattg ttactttctt aaataaagtc tgtaaactca atcgtttgct tggtatttta
    53641 attaccttgt gtactttggt ctggggaatg gtcataggtg ttgtctatct cttacctatt
    53701 ttgattaatc agttatctag tttgattata tctagtcaaa ctatttatag tcgagtacaa
    53761 gacttaatca tagacttatc taattatcct gcgctccaga atttggatgt agaagctaca
    53821 attcagcagt taaacttatc ctatgtggat attcttcaaa atatcctaaa tagcgtatca
    53881 aatagtgtgg ggagcgtctt gtcagctctt atcagtactg ttttgatttt gattatgact
    53941 ccagtttttt tggtttattt cttattagat ggacataaat tcttgcccat gcttgaaaga
    54001 acgattctaa agagggatcg cttgcatatt gcaggcttat taaagaattt aaatgcgacg
    54061 attgctcgct atattagtgg agtttcgatt gacgcaatca ttataggttg tttggcttat
    54121 attggctata gtattattgg tttaaaatat gctttagttt ttgccatttt ttctggtgta
    54181 gccaatttaa ttccttatgt ggggccaagt attggtttga ttcctatgat catcgcaaat
    54241 atattcactg atccccatag actgctgatt gcagtgattt atatgcttgt tgttcagcag
    54301 gtagatggca atatcttata tcctcgaatc gtaggaagtg ttatgaaggt tcatccaatc
    54361 acgattttag ttttactttt gttgtcaagc aatatctatg gtgtagttgg aatgattgtc
    54421 gcagtgccaa cctattctat cttgaaagaa atttctaagt tcttatcccg tttgtatgaa
    54481 aatcataaaa taatgaaaga acgagaaaga gaattagcta agtaaaagtc aggagaaccc
    54541 tgatttttct ttactggaag tggcctttag attagaagac tgaaaataag ttaaagtctt
    54601 aaactaattt tcacagctaa gaatagtaga agttaatctg ataaaaatcg aaaaaaccag
    54661 tggaattctg tgtcagggta agttccactg gttttcatag tctattaaag ttcgaatgaa
    54721 acctatttat agtagattga aactagaata gtacacctct aattctaaaa cattgttaga
    54781 a
//
LOCUS       DAVLDI010000007        51616 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLDI010000007 DAVLDI010000000
VERSION     DAVLDI010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51616
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.007"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..1387)
                     /gene="pcpA"
                     /locus_tag="VXD01_000390"
     CDS             complement(<1..1387)
                     /gene="pcpA"
                     /locus_tag="VXD01_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV0600836.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNRGV"
     gene            1722..1904
                     /locus_tag="VXD01_000391"
     CDS             1722..1904
                     /locus_tag="VXD01_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0600837.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            1849..2698
                     /locus_tag="VXD01_000392"
                     /pseudo
     CDS             1849..2698
                     /locus_tag="VXD01_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(2750..3112)
                     /locus_tag="VXD01_000393"
     CDS             complement(2750..3112)
                     /locus_tag="VXD01_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600838.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNIEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(3403..5283)
                     /locus_tag="VXD01_000394"
     CDS             complement(3403..5283)
                     /locus_tag="VXD01_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0600839.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRHDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(5277..6146)
                     /locus_tag="VXD01_000395"
     CDS             complement(5277..6146)
                     /locus_tag="VXD01_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0600840.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIRGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAGKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNCNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(6229..8874)
                     /locus_tag="VXD01_000396"
     CDS             complement(6229..8874)
                     /locus_tag="VXD01_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV0600841.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(8965..10245)
                     /locus_tag="VXD01_000397"
     CDS             complement(8965..10245)
                     /locus_tag="VXD01_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV0600842.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADTKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            10416..12500
                     /locus_tag="VXD01_000398"
     CDS             10416..12500
                     /locus_tag="VXD01_000398"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV0600843.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGAWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDVAPDLEGKLFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(12540..14219)
                     /locus_tag="VXD01_000399"
     CDS             complement(12540..14219)
                     /locus_tag="VXD01_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV0600844.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIHWIGNERGH
                     AGDPLWQKMNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLCKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            14974..16203
                     /gene="arcA"
                     /locus_tag="VXD01_000400"
     CDS             14974..16203
                     /gene="arcA"
                     /locus_tag="VXD01_000400"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV0600845.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            16264..17277
                     /gene="argF"
                     /locus_tag="VXD01_000401"
     CDS             16264..17277
                     /gene="argF"
                     /locus_tag="VXD01_000401"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV0600846.1"
                     /translation="MNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHYL
                     AGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITEDA
                     DEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPAF
                     HDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLYI
                     PKV"
     gene            17442..18389
                     /gene="arcC"
                     /locus_tag="VXD01_000402"
     CDS             17442..18389
                     /gene="arcC"
                     /locus_tag="VXD01_000402"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV0600847.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            18600..20111
                     /locus_tag="VXD01_000403"
     CDS             18600..20111
                     /locus_tag="VXD01_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV0600848.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     HPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            20133..21464
                     /locus_tag="VXD01_000404"
     CDS             20133..21464
                     /locus_tag="VXD01_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV0600849.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKETGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(21870..22160)
                     /locus_tag="VXD01_000405"
     CDS             complement(21870..22160)
                     /locus_tag="VXD01_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600850.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(22148..22400)
                     /locus_tag="VXD01_000406"
                     /pseudo
     CDS             complement(22148..22400)
                     /locus_tag="VXD01_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; frameshifted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            22604..22681
                     /locus_tag="VXD01_000407"
                     /pseudo
     CDS             22604..22681
                     /locus_tag="VXD01_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(22799..23683)
                     /locus_tag="VXD01_000408"
     CDS             complement(22799..23683)
                     /locus_tag="VXD01_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0600851.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(23827..24978)
                     /locus_tag="VXD01_000409"
     CDS             complement(23827..24978)
                     /locus_tag="VXD01_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV0600852.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMVTNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVANGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(25124..26890)
                     /locus_tag="VXD01_000410"
     CDS             complement(25124..26890)
                     /locus_tag="VXD01_000410"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV0600853.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(26947..30063)
                     /locus_tag="VXD01_000411"
     CDS             complement(26947..30063)
                     /locus_tag="VXD01_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV0600854.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            complement(30073..32367)
                     /locus_tag="VXD01_000412"
     CDS             complement(30073..32367)
                     /locus_tag="VXD01_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0600855.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPVNLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(32426..33226)
                     /locus_tag="VXD01_000413"
     CDS             complement(32426..33226)
                     /locus_tag="VXD01_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0600856.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(33223..33996)
                     /locus_tag="VXD01_000414"
     CDS             complement(33223..33996)
                     /locus_tag="VXD01_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0600857.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(34021..34491)
                     /locus_tag="VXD01_000415"
     CDS             complement(34021..34491)
                     /locus_tag="VXD01_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0600858.1"
                     /translation="MPIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(34482..34913)
                     /locus_tag="VXD01_000416"
     CDS             complement(34482..34913)
                     /locus_tag="VXD01_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0600859.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(34906..35346)
                     /locus_tag="VXD01_000417"
     CDS             complement(34906..35346)
                     /locus_tag="VXD01_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV0600860.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(35358..35996)
                     /locus_tag="VXD01_000418"
     CDS             complement(35358..35996)
                     /locus_tag="VXD01_000418"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV0600861.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            complement(36111..37514)
                     /locus_tag="VXD01_000419"
     CDS             complement(36111..37514)
                     /locus_tag="VXD01_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV0600862.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDVDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSTLLPEIVSEGNVLGRIKEE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLVYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            37690..38463
                     /locus_tag="VXD01_000420"
     CDS             37690..38463
                     /locus_tag="VXD01_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0600863.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(39590..41095)
                     /gene="adcA"
                     /locus_tag="VXD01_000421"
     CDS             complement(39590..41095)
                     /gene="adcA"
                     /locus_tag="VXD01_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV0600864.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(41105..41911)
                     /locus_tag="VXD01_000422"
     CDS             complement(41105..41911)
                     /locus_tag="VXD01_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0600865.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(41904..42608)
                     /locus_tag="VXD01_000423"
     CDS             complement(41904..42608)
                     /locus_tag="VXD01_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0600866.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(42608..43048)
                     /gene="adcR"
                     /locus_tag="VXD01_000424"
     CDS             complement(42608..43048)
                     /gene="adcR"
                     /locus_tag="VXD01_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV0600867.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(43203..44471)
                     /gene="dltD"
                     /locus_tag="VXD01_000425"
     CDS             complement(43203..44471)
                     /gene="dltD"
                     /locus_tag="VXD01_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV0600868.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(44464..44703)
                     /gene="dltC"
                     /locus_tag="VXD01_000426"
     CDS             complement(44464..44703)
                     /gene="dltC"
                     /locus_tag="VXD01_000426"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV0600869.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(44717..45961)
                     /gene="dltB"
                     /locus_tag="VXD01_000427"
     CDS             complement(44717..45961)
                     /gene="dltB"
                     /locus_tag="VXD01_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV0600870.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(45958..47508)
                     /gene="dltA"
                     /locus_tag="VXD01_000428"
     CDS             complement(45958..47508)
                     /gene="dltA"
                     /locus_tag="VXD01_000428"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV0600871.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMSGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(47529..47660)
                     /locus_tag="VXD01_000429"
     CDS             complement(47529..47660)
                     /locus_tag="VXD01_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV0600872.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(47974..49152)
                     /locus_tag="VXD01_000430"
     CDS             complement(47974..49152)
                     /locus_tag="VXD01_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0600873.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            complement(49609..50886)
                     /gene="ltrA"
                     /locus_tag="VXD01_000431"
     CDS             complement(49609..50886)
                     /gene="ltrA"
                     /locus_tag="VXD01_000431"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEV0600874.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEITKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKFLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRHKTLVGTPQGGNLSPLLSNVMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSASRFIEKRLGLKVNMTKAKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     RIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
BASE COUNT        15408 a        11166 c         9248 g        15794 t
ORIGIN      
        1 ctactccccg attagaattc tttttaggtt tagctacatc agtttcttgt tttatattat
       61 ctactttttc aacaatgata tcattactag tagataaatt tgatttaaga acatctttta
      121 tatgttctga tgttacatag aacttaacag tttcaggaat tgcaaatgta tcttttttca
      181 cagaaaactc tgtactttta ttcttaatat gaatttcctt taatgaatct aagacgccac
      241 ttaggaagaa ggacggcaat gagttgatat tattaccaat tgttaaactt tttaattttg
      301 gtaaaccgtt cataacgtgt ttaccaaaat ttttaacatt atctggtaat ataagttctt
      361 ttaattctaa attaccgtaa aaggctaaac gttcaatagt ttctaaacta tttggtaagc
      421 taatttcttc aagtttaatc gcatccgcaa atgcaaaagt accgattttt tctaaacctt
      481 cattcaattc gagttttttc aagtaagaat ttttattaaa cgaatatgat gcaagttctt
      541 ttgtctcttt aggcgtttta taactttcgt catttttttg acttggataa taaattaatt
      601 gagttttatc ttttgaaaac aaaacaccat caactgaggc aaacgattca tttccttctt
      661 caacatcaac atgttttaag ctagtagtga gtctaaatag attacttcct aatgttttaa
      721 ccgattttgg taatgttagt ttctctaaat ttgataaatt agcaaaagcc tcatgtgata
      781 ttaattctaa ttttgaactt gaggaaaagg ttagcttttt caatttttga ctaaaagaaa
      841 atgcacttgt tccaatatat tctagagatg caggcaattc aatctcttct aattcagaaa
      901 aatcaaaagc tctatcttca attttctcca gctgactgcc tttgtcaaaa ataatagttt
      961 tagctttact tccatggaag cctttttttt gtattttttt tatgcttgat gggatagtaa
     1021 tagagctagg atagtagaca attctacctg tttcatctgg ataataacta aaagcttgac
     1081 tagctacttc agtaacggta aatactttat cacctactgt gatttttgta ggaatcgtga
     1141 atggttttcc atcttgacca gcttcaaact ctacaggagt aactccatta cccacttgaa
     1201 cagttcctat gttaccttct acagttagaa ccttatattt gatattattt tgttgaataa
     1261 tacttccaac tttagtctct ttgattactt ccgaactagg agtatctgct aggattggtt
     1321 cattagggac atatgctgct aaaataaccg cagctgtagt taatgataat attgtagttt
     1381 ttttcattta aatttcctta catatttatt ttctaataga tataaaatta taactttgct
     1441 agccgttgtt ataaaaagtt ttattcaatc attatctagt agaatagagt agtacatttt
     1501 ataaattgtc atctctccat aaacacagta tatcattttt aaattttaag tcaaggaaaa
     1561 ttaacccact ttaatttctt ttttaacccg tgttaaaaaa gaaattaaag tgggttaaaa
     1621 aagaaattaa ctgagtaaaa actctcgaaa ttcaattcgc tatattatca ctcaacttga
     1681 acaaatacca gaaccacaaa aaacagatgt aaaggaaaaa tatggactta aaatttgaag
     1741 gggttgattt agaatacaaa aaagctaaaa acaatcttcc agagtctttc tgggaaacct
     1801 actcagcatt tgcaaataca aatggcggga aaataattct cgggatagat gaaaaaaaca
     1861 ttgacaccta ccaaagagtc aatagactcc ctgcgaaatt atgaagcaag taaacaatta
     1921 actgatacac gatttaagcg tcttgttggt gttcagcgca cgacttttaa agagatgtta
     1981 gctgtattaa aaacagctta tcaacttaaa cacgcaaaag gtggacgaaa acctaaatta
     2041 agcctagaag accttcttat ggccactctt caatatgtgt gagaataccg cacttatgaa
     2101 gaaattgcgg ctgattttgg tatccacgaa agcaacttaa tccgtcggag ccaatgggtt
     2161 gaagtaactc ttgttcaaag tggtgttacg atttcaagaa ctcctctcag ctctgaggac
     2221 acggtaatga ttgatgcgac ggaagtacaa atcaatcgcc ctaaaaaaac aattagcgaa
     2281 tcattctggt aaaaagaaat ttcacgctat gaaggctcaa gcgattgtca caagtcaagg
     2341 gagaattgtt tctttggata tcactgtgaa ctattgtcat gatatgaagt tgttcaaaat
     2401 gagttgcaga aatatcagac aagttggtaa aatcttggct gacagtggtt atcaagggct
     2461 catgaagata tgtcctcaag cacaaacttc acgtaaatcc agcaaactca agccactaac
     2521 agctgaagat aaagcctata accatgcgct atccaaggag agaagcaagg ttgagaacat
     2581 ctttgccaaa gtaaaaacgt ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg
     2641 cttcggatta cgaatgaatt tgattgctgg tattatcaat catgaactag gattctagtt
     2701 ttgcaggaag tctattgaaa tactaagcct acacagactg atttcaattt taccattctt
     2761 catagtcaaa accatcataa tctggatatt gttctggcga cgttccaacc gaacgtacga
     2821 gataagcttc ttcgtcctct gtctcgattt ctctcagcac ttggcattca aaacgccatt
     2881 catcaccgaa gtcgaaaata aacttaaatt tttgtttgac acttaggcta tccagataga
     2941 cattttctgt gtaacgttct tcaacatcgt cactaacaaa gctaagaaag taagaatctg
     3001 catgactcca ctcaatatta tccatgaaaa atgcgtgagc atgatcattt gcaaaatcaa
     3061 aactccataa aatcacatct gctagttccg ctaacgtttt tgtttttgga atctatatat
     3121 gtcggtagca acctttttta aatttgacgg aaatgatcca agcctctaca gatgctggct
     3181 tttcagcttc tatttcttgt tttactaatt ttaactgtag catttgaaac cagataattc
     3241 ttctgtttca cgcgaaacac cctgcgccaa gcaaggtgtt cttgttttta tactcaatga
     3301 aaatcaaaga gcaaactagg aagctagctg caggctgctc aaaacactgt tttgaggttg
     3361 tagatggaag ctgacgtggt ttgaagagat tttcgaagag tattaagtcg tataaatcgt
     3421 cgaagctgtc gcaatggtat gccactggtt agctgtagtt gctgcgaaat ccttgtctgc
     3481 gtagaagtca gtaaatggta ggatttcaac ttccagctcg tcgatgcggt caagctggcc
     3541 agccagataa acctcgatac ggctttctgc tcgtttgatg cgttgcaaga gtccgcccat
     3601 acggatgtca actgtatcca aaccaaagac cttgttttct ttcagccatt ggtgactaaa
     3661 gagggcatgg aagtcttcaa tttggcttct aagttctggt aattcttgtc tggcgatttg
     3721 ttgtaaactt tctttatcat ccgcttggta ggcctgacga atgcgtcgtc ccacatctac
     3781 tttgctactt aaaatagcat tcaactgggc ctgagtttca aagagataag catagtttcc
     3841 agctttttct ttaatgttag caagcgtctc agcagcctga gcgaagtgcg gtttgtcctg
     3901 ttcaggtgtc atgtgtcggt caagtatcgg acaaagaaca tcctgataaa agacatatcg
     3961 gttgggattg atgccactga gattgcctgg taggtctggt aagaggttgg caaggtcaat
     4021 ctgcataaaa tcctcaaccg ttagaccagt attggtcttg aagtgcgcag acaaactatc
     4081 taggtcatgg cgatagctga gttctgccca gatttgcaag cttggtagga tagagaactg
     4141 ggcagtttca cccccattgt ctccccaacc cgttacgatg acttctttaa tctgattggc
     4201 acggcaggct ttattagcct cgatagccac tagacggcta aaatggttgt gaggtgtaaa
     4261 gccaatccac ttccaagctc cccctgcaaa tgcaaggtca tggctaatct tgtgatgatt
     4321 gcggaaatta cggttgtatt tttcctcgct atcctgataa taatcccagt aaaccagagt
     4381 cacacggtct ttgagacggt ctaggtagac acgagtttcc tctggaattt ccacatcacg
     4441 gtcgtactgg ccatccgctg acatgagttt gaagaacata tcactccaca tctggcagtg
     4501 gaaaccatat ttgtcagcaa tatccagcac gcgctccaag tgttggcaca tgaggagact
     4561 acgatccaca acaccgttca aaatcaggta gcgtcccaaa ccaaccaagt gggcttcgtc
     4621 catcccgata ttgaccttgc gagtcttcag tttagacaac gtggcaaaca tgccatcaat
     4681 caggtcataa accttttctt cgccaatgag aagaatgtcc tctacatcac ggagctcctg
     4741 cacttccttg acaccccatt tgacaaaggc cgacaagtgg gccaaggtct ggatgcatgg
     4801 tacaaaggtc atgtcaaact gttgagcata ggcttcgatt tcctgcaact cctctgctga
     4861 ataagctcca cggaaatagc caaagtaagg ctgtccttca atctggtaag tgtcttccat
     4921 gtaaagctca aaggttgagt agcccatgag agccaagacc tcaatcatct gcttggcaga
     4981 agccacattc agcaccgcat ttcgagaaca gtcaaccatg taagccaaat cttcgtaagc
     5041 tgcttgttcc tcaatctcta ctttatcagc ttctgctaga actgttacca acaaggataa
     5101 ggcacgataa agttggtgag gtttgcggta ggtcaattga tagtgacctt cctcaccctg
     5161 gatagagata gaggcttggt cagactgagt gacagccact tccacatctg gtagagaaat
     5221 gtgacctttt aaaacctcaa tagcttgcgt ttgtttggga ctaagtcctg taaatcttac
     5281 cattgctttt cctcctgtag ccagttgaca agggcaccgt agagatttgc atctgcgtga
     5341 taggtgcagg cctggataac tggggcgacc gtgtattctt cgtaggtatc gacaaagtta
     5401 tcaacagcct tcttgacacc ttggataaaa tctggatttt gactgataga gccacccaga
     5461 ctgatgacat ctggatcgat cagatactgg atattgagca agccttgcgc cagattgcag
     5521 ttcatgcgct caatggcttc ttgacaaaga gcattaccag ctgcggcctc ttggtaaatc
     5581 ttgcgaccgt cccaatcagt atgaccagat ttttcaatta cgtatcgtac catattccca
     5641 gttgatgcta gttgcgacca gttattaagt tttccagcag gggcaagggt tgtcatgtag
     5701 ccaaattctc cacccagacc gtggcgacct cgatgaagtc taccattgat aatcatggct
     5761 ccgccaatcc ctgtcccaat cacgacacag gctgcatttt caagctctgg atgagctagt
     5821 agttcactga gtccaacgca gttggcatca ttttctaaat ggacaggtag ctgataagag
     5881 ctaagagcct cataccaaga aaagccacgg atgtagggca ccgcactgaa gccatcaatc
     5941 acacctgtct cttgattgac tgcacctgga acgctcatag caatcccact gtaatcctgt
     6001 tctgacaagc gttgatctag ccacgctagt aaatcctcca agttttcagg cgttgaaata
     6061 cttgtcttat ccagtatttt cccatcagga gtcagactgg caaacttaat cccagtccct
     6121 ccgatatcaa tcgttgcaat ggtcattgtt tttaccataa aagaggcgaa tcagcagtta
     6181 gttcttactt tttcgcccct cctttctttt gatgtttact ttttgaaatt aaatttcttc
     6241 ttttttgatg aattctgtac gaatctcttg tggagccaat agtcctgaat gaactggata
     6301 tggtcgctca agtaagtcaa gaatggtttg ttgatgttct gatatgcgca cattttcttg
     6361 actcatatta tagtaacgaa ggacatagcc ttcttcattt tccgccactt taaaggctgt
     6421 tggacaaact tgcggtatgc tgagaacaga atggctcaag aggctaccag tcgcaaccac
     6481 gcttccttcc tgtctagcaa gctgaaggct ggtaaacggt gtctgcaagg ctttggcacg
     6541 acgataggct gagaagcgtt cttgggcttg gtggcattca agtgcaaact cgacttcaaa
     6601 ctcacgcaag cattgtgctt ctggcgttgg gaagtagccc cagtcaccta gctcacctga
     6661 tgcacgcaaa atggtcacgg caatggtgtt atccccaagg atttcgtatt cattcaatcc
     6721 cttgttggat acagtcaccc ctttttcatc gtcatacaga ctgacaaaag cttgttggtg
     6781 ttgaggattt tcaggatttt cccatgaagc agctggtttg tttggtcgtg tcaccacctc
     6841 atagatactt tcagaatcat tgcttggacg cgtgttatga gtcttgacca agagacggat
     6901 acggtgatcc ttggcagtgt tagtaaagcg agtcttgaag cggatttgtg gattgtcaac
     6961 gaagacagtc aactcagttt ccagaggaat gtttgtcaat tcttctgacc gtccagcctc
     7021 acgcttcata aactcgatga taccttgttg ctcttcttct agcttttcat ccgcactgac
     7081 aggcacggtc aattcatgtt tgagcaagat tttagcatag cgatctgtgt tttccaatac
     7141 ctcgtggccc ttaagctctg caaagattgg ctctgttcct tttggttgga aatagatata
     7201 ctcgtttccg atgtcacccc ggtcttcaaa gcggataaag tcttcatagg cttcgtgagt
     7261 tgtcttgtca tagactgtga tgttgtcatc cacactcacc gttacgaatg gtgtatcaat
     7321 cactccgttt tggtaaatac cctcacggtg ttcttgtttt ccttccagca attggaaggt
     7381 tgtccaagaa agcggtgcta ggtgaactgg aatggtcaca cgcacttgtc gagcaatacg
     7441 agcttggcgg aacttatctt ttggtaaatc gtattcaaaa ttagctccga ggtcttcgat
     7501 tgtagcctct acaggacgac catccaagtc ctccacacgg taacttggca agataagagc
     7561 agccatcttt ttgtagcctt ctgttgggtg caattccttg aaatcacaag tcgccacatc
     7621 aatcactgtg ctgacagtat cgaccttatc atgcaagcct gtgttaatga cagtaaagag
     7681 atagtcactt tgagccttat ccgtagcaat tttacccttc cactcattga gcaaattact
     7741 tttaacaaag tttcctactt ggttgacctt ggcaaaacgc gtttccatct cgcggtgaac
     7801 ttcgtccacg ctacagccac agatactatc atgtggcgca ttctgcaaaa gtgttttcca
     7861 agcataggtc aactggtcct tgtggttgtg tccaccagtg ataatagtca agggttctac
     7921 cacttgctct aggaggttgc tattttcttg gaaggcttgt tttaggtaaa tgcgggatga
     7981 agaagtgttg gcaagtgtgt accagccatc tgtttcctga ctggtcaact cacctgtaac
     8041 agttgataag tgttcaggaa gcgcaccttc tacagcttga acatattcat caaaagaact
     8101 atgaacaaag attacatccg ggaagagttc atttgccaca cgaatggctt cgctcagatt
     8161 tttctggaca ggctggtggt cacagccgtt catcatcaac cattggttgg tcgaagcgta
     8221 ggcacgcaca tctgacaatt tttgtttcca gaaggtcaag gcctcatctt tgtcaactgg
     8281 gatttcattc ccattactgt accagttggc aaagagaata cctaaaacac gactaccatc
     8341 cacaccctgc cagtacattt ctgaaaactg ggatgtaaac tgctcatctt caaggacttg
     8401 gttgtcaaat ccaatcggct tcacaccacg accaaaggcc gccacgtgaa tgcctgattt
     8461 ttgaagaatt tgaggcgctt gtcccatatt tccaaaggta tctggaaagt agccaatctg
     8521 ggttgattta ccccatttgg cagcttcttg ttgaccaatc aaggtattgc ggacattggc
     8581 ttcactggag atcaagtagt catcctgcaa gatgtaaaag ggaccaattt taagtttgcc
     8641 ctcgtcaatg tagcgttgga ccttgtcacg attttcaggg cgaatttgta agtagtcgtc
     8701 aaggacaata gtttgtccat ccaagtggaa actcttgaac tcagggtcat tttcaaagag
     8761 atcaaagaga ttgtcaaaca attccaccaa ctgcatacga tggctttcaa aaggcaagta
     8821 ccactcacgg tcccagtgac tatgtgagat aatatgtaca acaacatttt ccatgaagta
     8881 aaacctcatt ctaaatttaa attttaacgt tttaaatgta aacttgtgat tctgataaga
     8941 atcggttgag ctaaagcgag ccccttagcg aatatccaag taatccaaga ccaactcaca
     9001 gaacatcatg ttagcccagg agaaccattc acgagagtag agggtcggat catctacgtg
     9061 gaagctttcg tgcatgacac ctgtaccacc atcgcaggca accagctgat ccagcaagaa
     9121 ttttttctct gccttatctc ttgttgtcaa tccttggata gaaagggcga ttggccagat
     9181 atagcgatag aaggtatgag aacttccgag accgctagcg tattctcctt ggtagaagta
     9241 tggattttca gagctcaaaa tggtacgacg agtagcttga tacacttcat catcgaccga
     9301 acagtagccc agatagggcg cagctagtag acttggtaca tttggatcat ccatgatgct
     9361 ggcatttcct aggccatcca cttcaaaagc gtaaatcttt tcgcccttgc tgttggtggt
     9421 gtaagcgtag ttttcgattc cttcttggat ttcatcctga agacgcttgg tatcagcaat
     9481 aacactctgg ctatcagcta ggtttaatgc tgcgaagatt tcttgcacat aacccaagac
     9541 tactacagca aacatatttg acggaatcaa gtaactatac tggcaacagt catcactcgg
     9601 acgaaaggct gaccaagtca tacctgtcac tgcaaagtca ggtccaaagc catcatttac
     9661 caaggtgtct tccttacggt ccgtatctcg gacaaaacga taaggagagt tcttgtggtc
     9721 ttgttcaact gtccatagat ggagaatttc cttagtcgct gcgacaaaag tctcatcaaa
     9781 ctgaccagtc tcgccagtct ctttccagag gagataagcc aactgcaaag gatagcaaag
     9841 cgagtccacc tcatacttgc gttcccaaat ccagccatta aggtcggtgt ggtcggtctc
     9901 gtggtgcccc ttccagtttt cctctatgtt gaaggaattg gcataaggat ccttgagtac
     9961 caaggtcatc tgacgtttga ccaaacctgc aatggtctga cgcaggaggg catctctttt
    10021 agctacatga aggtagggtc tgagttgggc tgtcgaatcc cgaagccaca tagcaggaat
    10081 atccccagtc aagacaaaag ttgaaccatc ttctaagatt tcaaccgtat tgtccaaggt
    10141 atcggtgtag caacgctcga aaacatccac ccactctgga tggtccttag cccgctctgc
    10201 tacttcatct agccattctc taacaatttc tttcgaataa atcatcgtgc aatttcctct
    10261 ttcaaacaag tttcattttc agtatatagc ttttgagaca gaaaatacat acacaaatga
    10321 tagtcatttt tctacaaaat agttattttt gaaactcctt ttctaaaggc cctctttttc
    10381 tgatataatg tagaaaaaca gctaaaggaa agactatgaa accactactt gaaaccatcg
    10441 atacccgctt tggtactgct agcaagcatg ccttctctcg gggaaatacc ctgccataca
    10501 caggcgtgcc ttttggaatg aattactttg tgccccagac cagtgaccag gatggagctt
    10561 ggttttttga tccgcatctg cctatctttc aggggattcg attaactcac cagcccagtc
    10621 cttggattgg ggactactct tggctccttc tgacacccgt caccagtcaa ctgggtggag
    10681 acagcctctt tcaccgccaa tcttcctatg atagggataa ggcctctttc caacctcatt
    10741 atctaaagat tttctccctg cgctatcaga ttgaaaccca gctcacaccg acttgctacg
    10801 gtgcttctat tcgtttgaag caaaagcaag gcaaagccct ctccctctat cttcacgcaa
    10861 cagatgaact gacagtagag caagtagata agcgaactct tgccctgcga caagaaggta
    10921 aaactgaaac caacaaaaat tcgctaacga tgtttactgc cctgcaaatg aacacggata
    10981 ttcttgctat cagccaagaa gctggggact ggcgaattga cttagcaagt agtcaaaccg
    11041 agatgcaact agccacttct ttcatctctc cttctcaagc tctaatcaat ctacctcaag
    11101 aagattttga tagctgtaaa acaagtgccc aagcggattg ggaaaatctc ctccatcgtt
    11161 ttgacattat agagacagga gaggctgacc gaaccttctt tgaccactgc ctctacagac
    11221 tcttcctctt cccacagact ttttatgagg ttgatgagtc agggcaagcc atccacatgg
    11281 atctggctac tggtactgtc aagcctggtg tcctctttag caacaatggt ttctgggata
    11341 ccttccgcac caccttcccc ctctttgccc ttatcatacc ggagcactat caacgctttt
    11401 tagaaggttt cctcaatagc taccgcgata ctggtttcct tccaaaatgg ctggctccag
    11461 atgaacgggg tatgatgcca ggtacacttt tagacggtat tatcgcagat agcgcctgca
    11521 aggacgtggc ccctgaccta gaaggaaaac tcttccaagc catgctcgaa acagccagca
    11581 aagccgaccc tctcggaatc aatggccgcc acggactagc ccaataccaa gaactaggtt
    11641 acctctctac cgaccaccac gaaagtgtta gccatactct agactatgcc tatagtgact
    11701 tttgtatcgc tagctgtgcc aaaaaactag agaacataga aatcgctgaa acctacaagg
    11761 ctgcttcaca aaattaccgc cagctatttg acgctgagac aggttacatg cgagcacgag
    11821 acaatcaagg aaactttcac cctgacttct ctccttatag ttgggggcga gactacgctg
    11881 aatgctctgc cattcaagct actttaggcg ttctccacga catccctggc ttaatccaac
    11941 tgatgggtgg aaaagaaacc tttagcaact atcttttgaa agcttgtcaa gatgctcccc
    12001 tctttgaaac aacaggctat ggttacgaaa ttcacgaaat gagcgagatg gctactgctc
    12061 cttttggaca aatagccatt tccaaccagc ctagtttcca cattccttat ctcttccgct
    12121 acagcgatta ccctgactac actgcccttc ttatcaagac gctccgtcag aaagcttttc
    12181 acccaagttg ggaagcctat cctggagatg aagacaatgg tagtctctct gcttggtaca
    12241 tctggtcagc tctcggattt tatccaacct gtccaggaaa accaagctat gacctcggaa
    12301 tccctctctt tgaccatcta cgagtctacc tcgctaaaga agataaatgg ctggatatcc
    12361 atactaaaca aaaccacaac cattttaact ttgtcaaaga atgccgactg gacaaaacac
    12421 tcgtatcaac tattcaacac caagacctct taaaagctga acaactaact ttcaccctca
    12481 gctggttacc aagtcactaa taaccaaaag aacctttgca tcgcgcaaag gttcttcttt
    12541 tatgaaactt ggacttgaag ttgatccaca agctgaccat ccaccgttag gttcagatag
    12601 aaatccaagg ttttatctcc tgcgaaatac agggttggta gatgcaaatc ttttttgctt
    12661 tcccctgctt ggaattgaag gacttgaatc tcatcctgat aggcgacacc atggacacct
    12721 gtccccggtt gaatcgaaat cttagcctct aaagaggagc tactttcact acgttcaatc
    12781 ctaaaatgaa gagtctctcc ctttgccaca gctaggcttt tttctgcaaa tgctagttcc
    12841 tgaacaactt ctttttttga taatccagga gttttacaaa gggaaatctt ggtcaataca
    12901 ggaatagatt gtgcctcggt aatcatcacg cgcacctttt gtgcctctac tagcggacct
    12961 cgcaagaggc gcttatgacc aactgtgaag cccctgccaa attcctgcca gacaccatcc
    13021 acctctactt gcacatgaaa agcagcgatt cgttgcccta gcttcaaatc ttctcttaac
    13081 tcaattacat caaaagtttt aggagaacct aaatcgagtt ctaactggat gggcaagtct
    13141 gcatcgcttg cccaagagct ggtctcaagg ccgtctgtca aatggcgaca agcaaagtct
    13201 gcggaaagag ctggaccaga tacctcagct cccagagcca aatcttcttt atagagctca
    13261 ttgcgatagg tcgcaaattc ataaagtcgt tcaatatcct ttgcatcaaa gagcccagct
    13321 tgattcggcg gaatattaag caagagtgga gttcctcgcc ctactgagtg aaagtagatt
    13381 tcgaccaact cctcgagaga cttaggatcc tgatcctcat ggtagaacca gcctggacgg
    13441 atggaaacat ctgcctctcc gatcgaaaaa atcgtgcccg agggatcccc gtgctgaaga
    13501 tagttcagct ctgcttctgt tcctagttta tcaggattca tcttttgcca cagtggatca
    13561 cctgcatgcc ctcgttcatt gccaatccag tggatactgg tgccttctgt tgaaaaaatc
    13621 aaacaatcgc cctgcaagtc acgaatggtt tcaaaccatt tttcaaattc ataattaacc
    13681 ttttgcgcgc cctctcctct ggcaccatcc atccaaacct cagcgaactt accagcattc
    13741 ccatagttag gatttgataa gatttccttc aactgagcca gataataggc attgtagtcc
    13801 gcttctcggt ccacatgata gaggggacta tgggcatccc acggtgacag gtagaccccc
    13861 atatccatat caaactctgt ggcagcttgg gatacttcaa ggagcaagtc gccctttcct
    13921 ctcctccaag gactgacctt aaccgaataa tctgtgtgag ctgtcggata aaggacaaag
    13981 ccatcgtggt gcttgaccac caaaatcaac tttttgaagc ccgtttcctt gagcacacga
    14041 acccactcac gcgcatccaa ctgactcggg ttaaagcgct caggatcctc ctgtccagtc
    14101 ccccattctt ggtcataaaa ggtattagga ccgaagtgga taaaagctgc tagttcatct
    14161 cccagataag ctagctgagt ctgacttggt aacggtccat gcggtttgat tttcttcatc
    14221 gttatatatc tccttcttta gcaacttctc ttattcacaa ggttatccac aggttgtgga
    14281 taataaacca tgatctaaca gtcagctctt tccaactcca actggtaggc tcaggatttt
    14341 tctcctcaat attccctctt caaacagctc tgtcatatgg ttctgctaac acctctcaga
    14401 atgctactct ccataattat tctcaggctt ctttcaggtc attgtgtgaa gaccattcac
    14461 tatccagact tttccacaga ttgtgaataa gtgattattc taagctatca cctcgtcgac
    14521 tataacaaaa aataaaaaga gggtcaataa gataattatc tcttcctaaa tactcagaaa
    14581 agattctata atttgtacaa ttgaacaaga aatgcttctc caaaatctat cttcaaaaga
    14641 atgttgcatc tttttatcct ttcacacaaa catttctctt tatacagatc caagtgataa
    14701 ccagatgata attggacact ttttggtcat ttgtatattt tttgaaaaat tttttaaaaa
    14761 aattttatat cctttttata gaagtttatg catttgtatc tatgtattct atcctatgtt
    14821 atgtataata acataaaatt gtgctaaaca tcataattta tattattttc cgagaaatta
    14881 tagccattga cattacctag gaattgcgtt ataacataca tgtaagcggt acccaaaatg
    14941 gtgccaagtc aaaattttta aggaggaaaa tacatgtctt ctcatccaat tcaggtcttc
    15001 tcagaaattg ggaaactgaa aaaagttatg ttgcaccgtc caggcaagga gttagaaaac
    15061 ttgttgccgg actatcttga aaggcttctt tttgatgata ttcctttctt ggaagatgct
    15121 caaaaagaac atgatgcatt tgcccaagct cttcgcgatg aaggaattga ggttctctac
    15181 ctagaacaac tcgctgctga atcattgacc tctccagaaa tccgcgatca atttatcgag
    15241 gaatacttag acgaagccaa catccgtgat cgtcaaacca aggttgctat tcgtgaatta
    15301 cttcacggca tcaaggacaa ccaagaattg gttgaaaaaa caatggctgg gattcaaaaa
    15361 gttgaattgc cagaaattcc tgacgaagct aaagatctaa ctgacttagt tgaatcagag
    15421 tatccatttg caattgaccc gatgccaaac ctctatttca ctcgcgaccc atttgcaaca
    15481 attggaaacg ccgtatcgct taaccacatg tttgcagaca ctcgtaaccg tgaaacactc
    15541 tacggtaagt atatcttcaa ataccaccca atctatggcg gaaaagtgga tttggtctac
    15601 aaccgtgaag aagatacgcg tatcgaaggt ggagacgagc tagttctttc taaagacgtc
    15661 cttgcagtag gtatctctca acgtacagac gcagcttcta tcgaaaaact tttggtcaac
    15721 atcttcaaga aaaatgttgg cttcaagaaa gttttggcct ttgaatttgc taacaaccgt
    15781 aaattcatgc acttggatac tgtcttcact atggtagact atgacaagtt cactattcac
    15841 ccagaaatcg aaggcgacct tcacgtttac tcagttactt acgaaaacga aaaacttaaa
    15901 attgttgaag agaaaggtga cttagctgaa cttcttgctc aaaaccttgg tgtagaaaaa
    15961 gttcatttga ttcgttgcgg tggtggcaat atcgtagcag ctgcgcgtga acaatggaac
    16021 gacggttcta acactttgac catcgcacct ggtgtggtag ttgtttatga ccgcaatacc
    16081 gtgaccaata agattttgga agaatacggg cttcgcttga ttaagattcg cggaagtgaa
    16141 ttggttcggg gccgtggtgg acctcgttgt atgtctatgc catttgaacg tgaagaagtg
    16201 taatagctgt tcggcattcg tcaatagaaa atgtaaaaaa tagaaagagg aaataataaa
    16261 atgataaatt cagtattcca aggacgcagc ttcttagcag aaaaagactt tacccgtgca
    16321 gagttagaat accttattgg tctttcagct cacttgaaag atttgaaaaa acgcaatatt
    16381 caacaccact accttgctgg caagaatatc gctctcctat ttgaaaaaac atctactcgt
    16441 actcgtgcag cctttacaac tgcggctatc gaccttggtg ctcacccaga atacctcgga
    16501 gcaaatgata ttcagttggg taaaaaagaa tctactgaag atactgctaa agtattggga
    16561 cgtatgtttg acgggattga attccgcgga ttcagccaac gtatggttga agaattggca
    16621 gaattctcag gcgttccagt atggaacggt ctaactgacg aatggcaccc aactcaaatg
    16681 ctcgctgact acttgactgt tcaagaaaac ttcggtcgct tggaaggctt gacattggta
    16741 tactgtggtg atggacgtaa caacgttgcc aacagcttgc tcgtaacagg tgctatcctt
    16801 ggtgtcaatg ttcacatctt ctcaccaaaa gaactcttcc cagaaaaaga aatcgttgaa
    16861 ttagcagaag gatttgctaa agaaagtggc gcacatgttc tcatcactga agatgctgat
    16921 gaagcagtta aagatgcaga cgttctttac acagacgttt gggtatcaat gggtgaagaa
    16981 gacaaattcg cagaacgtgt agctcttctt aaaccttacc aagtcaatat ggacttagtt
    17041 aaaaaagcag gcaatgaaaa cttgatcttc ctacactgct tgccagcatt ccacgatact
    17101 cacactgttt atggtaaaga cgttgctgaa aaatttggtg tagaagaaat ggaagtaaca
    17161 gacgaagtct tccgcagcaa gtacgctcgc cacttcgatc aagcagaaaa ccgtatgcac
    17221 actatcaaag ctgttatggc tgctacactt ggtaaccttt atattcctaa agtataattt
    17281 tagataataa accgtctacc aacagctatg agggctgcga ctaatagctt tagtccggtc
    17341 ctcttttatg taatggtaat ctattatttc ttataaaata tgtgaaaaat cattaaattg
    17401 aaatctaaac gcattctatt gagtgtgata aaggagaatt tatggcaaat cgtaaaattg
    17461 tagtagcttt gggaggaaat gcgattcttt cttctgaccc atcagcaaag gctcaacaag
    17521 aagctttagt tgaaacagct aagcatcttg taaaattgat taaaaatgga gatgatctga
    17581 ttatcactca cggtaatgga cctcaagttg ggaatctctt gctccaacat ttggcatcag
    17641 actctgaaaa gaaccctgcc ttcccactcg actcacttgt cgctatgaca gaaggtagca
    17701 tcggtttctg gttgaaaaat gctttgcaaa atgctctctt ggatgaaggc atcgaaaaaa
    17761 atgttgcctc tgttgtaacg caagttgtcg tagataaaaa tgatccagct tttgttaact
    17821 tgagtaaacc aatcggtcct ttctattcag aagaagaagc aaaagcagaa gccgaaaaaa
    17881 gcggagcgac tttcaaggaa gatgctggcc gtggctggcg taaggtcgtt gcctcaccaa
    17941 aacctgttga catcaaagaa attgaaacca tccgtactct tttaaataat ggtcaagtcg
    18001 tcgtagctgc aggtggtggc ggtattcccg tcgtcaaaga aaacaatgga catttgactg
    18061 gtgtcgaagc ggttattgat aaagacttcg cttcccaacg tttggcagaa ttggttgatg
    18121 cagacctctt catcattttg acaggtgtag attatgtatt tgttaactac aacaagccaa
    18181 accaggaaaa attggaacat gtgaatgttg cccagctgga agaatatatc aaacaagatc
    18241 agtttgcacc aggtagcatg cttccaaaag tagaagcagc tatcgctttt gtcaatggtc
    18301 gtccagaagg aaaagcagtt attacttccc ttgaaaatct aggcgccttg attgaatctg
    18361 aaagcggaac aattattgaa aaaggataag ttgttttact aataagatgt attctatttc
    18421 tagtatcttt atatcaaatt agaaattatt cttgaaaaca tgtacaatat ttcaaaagat
    18481 attagttttt tagactttaa tatggtaaaa caaatataaa tagaaagcgt tttcttgaat
    18541 gtttatttaa gaaagtagtt ggttttttac actttgttag acatcaggag gaaaaacaaa
    18601 tgagtgaaaa agctaaaaaa gggtttaaga tgccttcatc ttacaccgta ttattgataa
    18661 tcattgctat tatggccgtg ctaacttggt ttatccctgc gggggccttt atagaaggta
    18721 tttacgaggc tcatcctcaa aatccacaag ggatttggga tgtcctcatg gcaccgattc
    18781 gggctatgct aggtactcat ccagaggaag gttcgctcat taaagaaacg agtgcagcga
    18841 ttgatgtagc cttcttcatc cttatggttg gtggtttcct tggcattgtc aacaaaactg
    18901 gtgctcttga cgtagggatt gcctctatcg tgaagaagta taagggccgc gaaaaaatgt
    18961 taattttggt actgatgcct ttgtttgccc tcggtggtac aacttatggt atgggtgaag
    19021 aaacaatggc cttctatcca ctccttgtgc cagttatgat ggccgttggt tttgatagcc
    19081 tgactggtgt tgcaattatt ttgctcggtt ctcaaatcgg ctgtttggca tctactctga
    19141 atccatttgc gacaggtatt gcttcagcga ctgcgggagt tggtacaggg gacggtatcg
    19201 tacttcgtct gatcttctgg gttaccttga ctgctcttag tacttggttt gtttaccgtt
    19261 atgcggataa gattcaaaaa gatccgacta agtcactggt ttatagtact cgcaaagaag
    19321 atttgaaaca ctttaacgta gaagaatctt catctgtaga atctacactt agcagcaaac
    19381 aaaaatcagt tctcttctta tttgtgttga cattcatctt gatggtattg agcttcattc
    19441 catggacaga ccttggcgtt accatttttg atgactttaa tgcttggttg actggtcttc
    19501 cagttattgg taatattgtc ggttcatcta cttctgcact aggtacttgg tacttcccag
    19561 aaggcgcaat gctctttgcc tttatgggta tcctgattgg tgttatttat ggtcttaaag
    19621 aagataagat tatctcttcc ttcatgaatg gtgctgctga cttgctcagt gttgccttga
    19681 tcgtagcgat tgctcgtggt attcaagtta tcatgaacga cggtatgatt accgatacaa
    19741 tcctcaactg gggtaaagaa ggcttgagcg gtctatcttc acaagtcttt atcgttgtaa
    19801 cttatatctt ctatctacct atgtcattct tgatcccatc ttcatctggt cttgccagcg
    19861 caactatggg tatcatggct ccacttggag aatttgtaaa tgtccgtcct agcttgatta
    19921 tcactgctta ccaatctgct tcaggtgtct tgaacttgat tgcaccaaca tctggtattg
    19981 tgatgggagc tcttgcactt ggacgtatca acattggtac ttggtggaaa ttcatgggca
    20041 aactcgtagt cgctattatt gtagtgacca tcgcccttct tctccttgga accttccttc
    20101 cattcctata aaatagtgag tgaggtgatt ccatgaaaat agatataaca aatcaagtta
    20161 aagatgaatt tcttatatca ttaaaaacct tgatttccta tccttcagta ctcaatgaag
    20221 gagaaaatgg aacacctttt ggacaagcaa tccaagatgt cctagaaaaa actttagaga
    20281 tttgtcgaga cataggtttc actacctatc ttgaccctaa aggttattac ggatatgcag
    20341 aaatcggtca gggagcagag cttctggcca ttctctgtca tttggatgtt gttccatcag
    20401 gtgatgaagc agattggcag acaccgccat ttgaagcaac tatcaaagac ggctgggtat
    20461 tcggacgtgg tgtccaagat gataaaggcc cttcgctcgc agctctctat gcagtaaaaa
    20521 gcttgctgga ccaaggtatt cagttcaaaa agcgcgtacg ctttatcttt ggtaccgatg
    20581 aggaaaccct ctggcgctgc atggcacgct acaataccat cgaagaacag gccagcatgg
    20641 gctttgcacc tgactcatct tttcctctga cctatgctga aaaagggctt ctacaggtca
    20701 aacttcatgg ccctggatcg gatcaactag agcttgaagt aggaggcgcc tttaacgttg
    20761 taccagacaa ggccaactac caaggtcccc tctatgaaca ggtttgtaac ggtctcaaag
    20821 aaactggtta tgattaccaa accactgaac aaaccgtaac ggttctcgga gtgccaaagc
    20881 atgctaagga tgctagtcaa ggtatcaatg ctgtcatccg actagctacc attcttgctc
    20941 ctctccaaga acaccctgct ctcagctttc ttgcaacaca agcaggtcaa gacggcacag
    21001 gaagacaaat ctttggtgat atagcagatg aaccttctgg tcacctatcc tttaatgtcg
    21061 caggtctcat gatcaatcat gaacgttctg aaatccgtat tgacattcgg actcctgtct
    21121 tagctgacaa ggaagaacta gtagagttgc ttacaagatg tgcacaaaac taccaactcc
    21181 gctacgaaga gtttgactat ctagcgcctc tatacgtcgc aaaagacagt aaactcgtta
    21241 gcacactgat gcaaatctac caagaaaaga ctggcgataa cagtcctgct atttcatccg
    21301 gtggtgccac ttttgctcgc accatgccaa attgtgtagc cttcggcgcc ttattcccag
    21361 gagcgaagca gacagaacat caggcaaatg aatgtgccgt tctagaagat ttgtaccgtg
    21421 ctatggatat ttatgccgaa gccgtctatc gacttgcaac ttaatcaggc aactgtttct
    21481 acaaaaaaaa atcgaccgat taatgaactg caccccaaaa gttagacaga ataaatctaa
    21541 cttttggggt gttttattat gaaattgaat tatgaagata aagttcagat ctatgaacta
    21601 agaaagcaag gacaaagctt caaacagctt tcaaaaagat ttggtgtgga tgtttctggt
    21661 ctaaagtcat ctgaatcttt gagatgagct ttataaatcg cttttttcag tttttgcact
    21721 ggtatttcga taaactcaaa ctttttagcc gttgtattgc ctgattttat agtatgttga
    21781 aactagaata gtacacctct acttctaaaa catttttaga aatcaatttg actgtcctga
    21841 ttgatttgtc ctgttcttat ttcattttac tatatttgag ccacttcgtc tttaacggct
    21901 ttattcataa gctcttgtaa tttttcttta ctatcaatta cttctgattt tccgttgtaa
    21961 tttattgtaa taggttttaa cttacctaat ttctcgacac gctcattaat ttgatctttt
    22021 ttgaaggctg catatgtttt tcctaagatt ttttcgaaaa tatatttatc agatagcggt
    22081 ttgccttctt cttcagcttg gtttttgtat tgatttgaaa cataaggaac aaatccttca
    22141 tagtaaccta atgctcccat aagttcaaaa gcttgttttc taattcaaac cattgcaact
    22201 cagatttcag cttttcagat aaatcctgct catccaaata atgacttgaa attagtgctg
    22261 aactcgtttc tgtatcctgt acaggctgag cacccatacc agcaaaaaaa taaactcgtt
    22321 cctagcaaga ccgaacaagc tcctattgca tatttcctca aagaaaaacg ctgctttctc
    22381 tcaaattgaa attctttcat cccatctccc atcattcatt attactgtat attttgtata
    22441 tcagaaatag tttgtattca caaatctttc tagttattcc cttatcattc ctaattaagg
    22501 gagataacat acaataattt ttagttaaat gtatatcgat gttttttgtt tttcttaata
    22561 aacgcaatac aaaaagagcc tgttgccaag ctctttatac tcaatgaaaa tcaaagagca
    22621 aactaggaaa ctagctacag gttgctcaaa acaccgtttt gaggtagtag ataagactga
    22681 cgaagtcagc tcaaaacact gttttgaggt tgcagataga actgacgaag tcagtaacat
    22741 ctatacggca agacgacgct gacgtggttt gaagagattt tcgaagagta ttagtctatt
    22801 atttcttctc agcgcgaagg gctgacaaga tttgtgtacg gatatcatcc acaccatttg
    22861 gagtatttgg taaaaagatg gtttgatttc ctttagaggc aaaggtattc aaggtatcca
    22921 aatactggtt ggtcaagagg atagacatga tttgttcttc tgtcatgcca acattggctt
    22981 ccttgagttc ggtgatagac tctgccaatc catccacaat cgccttacgt tgttgggcaa
    23041 tccccacacc atgaaggcgg tctttttctg cttctgcttc agctgcagtg acaattttaa
    23101 tcttgtcagc ttccgccaat tcttgtgctg cgacccgctt acgttgcgcc gcattgattt
    23161 cattcatgga ttgcttaact tctgcatccg gttcgacctt ggtaatcaag gttttcacga
    23221 taatgtagcc gtaagtggtc atttcttctg ctacttggtg ttgaacctca agggcaatct
    23281 catctttttt ctcaaacaat tcatccaagg ttaattttgg aacagaagag cgaagagcat
    23341 cttcgatata agatttaatc tgagattctg gacgtatgag tttatagtaa gcatctgtca
    23401 cgctctgctc gttgacacgg tactgagtcg ctacattcat cataacgaac acattgtcct
    23461 tggtcttagt ctcaaccaca atatcacttt gcaacaagcg caactgaatc cgtgctgcaa
    23521 tcgagtcaat cccaaaaggc aagcgaatat gaataccgct attagcaacc ttttggtatt
    23581 tcccaaagcg ttcaataatc gccaccgact gctgacgaac cacataaact gtactcagtg
    23641 tgactatcac caataggagc acacaaacaa tcagaaaaat catgaaaaat attgccataa
    23701 tggaacctcc acaagtattt ttctagtatt atagcacatt taaagaaggc tgtgccgttt
    23761 ttactgcgat tttttctgaa atgtcaataa ttagaggtga attgtcctat tgtcgtccaa
    23821 tccttgctaa aataactctt tataaaaggc aatcgtttct tctaaggttg gcataaatgg
    23881 atttcctggt gcgcaggcat caatcaaggc attcttagaa aggtattcaa agtcgaaatc
    23941 tttttcttca ataccaagtt cagtcagttt cttaggaata cctactgtct cagaaagctt
    24001 ctcaatctca gcaatcgcat aatcggcaca ttcttgatct gatttacctt ctacatgaag
    24061 tcccaaggct ttggcaacat tgcggaaagc ttctggtaca cgtttagcat tttcacgttc
    24121 tataactggt agcaacatgg cacagcaaac accatgtggc aaattatata ctgcaccgag
    24181 ttggtgagcc attgagtgaa catagccaag accagcatta ttaaagctca taccaccaag
    24241 gaagatggca ttgaccatac cttcacgcgc ttcaatatca tgtccgtttg ctacagcacg
    24301 aggaagatat tccttgataa gctcaatagc accaatagac agtttcttgg ttacatcata
    24361 agcaccaggt gttaccaaag cttcaacagc gtgagtcaga gcatccatac cagtagcagc
    24421 agtcaaggct tgaggtttgg aaagcatgag ttcagggtca ttgacagaaa tcaaggcaag
    24481 gctattcttg tcaaccatta ccatcttaac cttgcgttct tcatcagtaa tcacatagtt
    24541 aatggtaatt tctgctgatg tacctgccgt agtattgata gctacaacag gaaggccttt
    24601 tttagcagac ttatgaagcc cttcataatc ctgtggtttt ccaccatttg taaccatgat
    24661 agaaatacaa ctagctgcat cctgtggaga acccccgcca agactgatga taaaatcaca
    24721 tccatgttct tgcaaagcag ctaccccatc tgtgacattc ttacaagtag ggtttggctc
    24781 tacatcgcta aagatgacat attcgattcc ttctgtatcc agtggtttta aaaccttagg
    24841 taaaatgtca ctgccttcga tgtacttatc tgtcaccaaa agtgcctttt tatagccaag
    24901 ttccttgata taaggaccca cttcatttac aacacctttt ccaataaggt tgactgccgg
    24961 aacataaaat gtagccatat aattttcctc ctgcgccttt gcgctatcta tttaacatca
    25021 ttatattact ttttgtattc gtttttaatt atttgtgaat tgtttaacaa atctttttaa
    25081 aaggatagga gggacgtaag ttcacctcct atataaacaa gttttattta tgtagtggtc
    25141 ccaacaactg acatgcacga tagtctgctg attctagatc ttctgttcca aataaggacc
    25201 aatttttagg tctaaagata tcttcctcag gtacattatg catattgaca ggaattctca
    25261 acatagaagc caaggtaatc aagtctgctc caatgtgtcc atatgttatg gctccgtgat
    25321 tagctcccca attattcatg acgtcataga cagacttgaa agcacctttt cctgtcaaac
    25381 gtggagcaaa ccaagtagtt ggccatcctg gatctgtacg attatctaaa gtatggtgaa
    25441 catcttcagg aagttcaagt gtgtaacctt ctgcaatttg taacactgga ccaacccctt
    25501 ttagaagatt gagacgtacc attgttactg gcatatcccc cttcgtcaag aaacgagttg
    25561 agaatcctcc tccacggaag tattcgcggt ttgctggtgg gaagtctgta ttttcaagca
    25621 tagcctgcac ttcactttct tccaactccc agaatggttt cataacaggt ttgccatctc
    25681 gagtagcttg acctgtacca tccaatgtac aagaaccaga gttgattaga tgtaagaagc
    25741 cagctgcagc acgaccctct aaagtatgtc ccgttacacg tttaacagcc tctggactcc
    25801 aataagtacg cacatcagca aatatttgtg gagtatttgt taatagataa ttaaagagca
    25861 tagacacacc atttagtgaa tcattctctg tcgcaaatac aaatggtttt cgaataccat
    25921 tccagtcaaa ctgagtattg aggaaagttt ccataaagtc cccatttggg aaatgatctg
    25981 tccactggcg ttgaccttgg aaaccagcta ctaaagcatg gtgaccaact gcttcttctt
    26041 caaaaccaag ttcagcaagt cttgggttac caaccattaa gtcacgtcca atcatgaaca
    26101 tcttaataac aaattcccat tgtttttctt tctcttcttt agaaagaatc aaatcctcac
    26161 gatttcggtc aaccccttct ttgatatgtt cttttaccca aaccatagca cgttcgaact
    26221 cttctgggtc ataaatacca cggtccatac ggcgcgtgaa ctccgtcata tctaccgatt
    26281 catttcgcat tcctaagtat tcttggaaga aatctggatt tacaatagaa ccaccaatcc
    26341 ccatcgaaac actacccatt gataggtaag cagtgtctct catcaagcca gttgcaagag
    26401 ctgcacgcgc ataacgtaaa agtttttctt tgacatcttc tggaatagct gtgtcactag
    26461 cttcctgaac atctcttcca taaatcccaa aggctggaat ccctttttga gcatgtgaag
    26521 ctagtacagc tgcaagatag acagctcctg ggcgttctgt cccattaaat ccccaaatag
    26581 catgaggaat atctggagac atatccatag tttcactacc ataacaccag catggtgtaa
    26641 ctgtaattgt tgcgcaaaca tttgattttt taaacaactc atgggaagct gcagcctctg
    26701 gaacacgacc aatggtagat ggagaaatca cacattccac aggttcccca tctggatatt
    26761 tcaatgtgct tgaaatcaaa tctgccacac ttttagccat gttcattgtt tgtacttcaa
    26821 gtgattcgcg tacaccttga cgacgaccat caatagtcgg acgaatccca atacgtggat
    26881 gttgaatcat actattttcc tcttattttt ctgtttcttt catactaccg atgataattt
    26941 ttaaaattac ttataagtat aaacctctac ctctgccaaa cttaaaggaa ttcctgcgtt
    27001 tctcaaagaa attctaacct tttttccctt cagccctttt aagtctatgg atagattatt
    27061 gctttctaaa ctgtcaatat gttgtttaaa aacttcatga ttatttgaat catatataat
    27121 aatatcaaaa tttgataatc tctgaatttc agcatctgtt ctattataaa taattaactt
    27181 ttctaattct tcggtttgtg ctaaatctat ctcccaccat gaaggagaat ctcctttggt
    27241 atgagtcact gaatgatgac cataatctcc gtttttattt ccatcaactg ctagacgaga
    27301 aaaaccattg taatccgttg aactctgtcg agtttctttg gttaatgcaa tattagaaag
    27361 tttcttcgga gttctctttg aaccatagac ttcaacttcc gctaaactta acggaatagc
    27421 tgctgatttt aattctattt tgactagctt agcccctaca gaaggtactt ttaaagataa
    27481 caaaccatca actactttat caaaatgtct tctaaaaact tcttctcctg atgaagatag
    27541 aaaaataaca tcaaaattag ataaacgctg aggttcggca tctgttctat tataaatatc
    27601 aactttagaa accgtaaact cttctcccag atcgacctgc caccaagcgt tagaatctgc
    27661 cttagtatga gtcaccgaat gatgtccgta atctccatct ttattaccat caactgctaa
    27721 agcagctaca ccctcataat tggttgaact ttgagtagct accttatttg tagagactac
    27781 tttatcttct gttattttat ctatatcctc ttcagattgc ttaccatctg attctctaaa
    27841 aacctctact tctgctaaac tcaaaggcac tccactcgtt agtaatttaa ctttaatata
    27901 ccttgctcct ttttctttga aatctagact aacagattca cccgacaaat tattaacatg
    27961 tttcttagca acttcgtttc tattattgtc atatagaatc acatcaaaat tagatagacg
    28021 ttgagtctca gcatctgtgc gattataaat tttaacaagc ccaactttat ccattttttt
    28081 caaatcgact tcccaccaag aaggattatc tgccctagtg tgtgttaccg aaccagagtt
    28141 aaaattacca tttctgttac catccacagc tctattaggg tctccattgt aatctacaga
    28201 actttgtgtt gttggttttg catatgctat attcaaatta ccatcattaa atttatctgg
    28261 tgttgggaaa gggactgggc ctgtcccttc agtatttata gacatctcta ccattccatt
    28321 atgattaacc gtaatggtat aaacatgggt attctcatcc caattttctg tataagtata
    28381 atgattttta tcgccactta tatttatctg aggtttatga ccagtatgcc cttttaatgt
    28441 aagtgttgtt gtcctaaagt cattatctac aggattgatg gaataatttt tgcttatcca
    28501 gttcgctaac tctaattctt ctttcttcca actttttgat gcatcaaaat ttcctgataa
    28561 tgcccacata gctgtcttat ctgtcctgta attgttcaat aaaatatgta aattatttgg
    28621 attttcttta acaacagcgt aagtatgtgg cgtcaaatct aacgataacg actttgtatt
    28681 attagtatac ataggcaaca ttacttgctg atttttattg atattagcat tactattata
    28741 aatataccag gaattaccta cacgctgagc atacccatct ccttcataaa gttttggata
    28801 aagcgagttt aaatagttga ctttactaga caattcctca ctatttttag tcaaaatttt
    28861 tgcattaggg aatatagatg aaatcttttc cttatcaatt ttctcatgta ttacaggaag
    28921 aatatgatat ctcccattat tatataaagg cattgtttca tcattcgaat aaagtccttg
    28981 ataaaatccg tttaatgaac taatcctacc ttctccattc caaaatacag cttttgttct
    29041 atttacaact tcttccttac ttggagctgg attttgtata gcatgtctaa agaaaggaat
    29101 aataccttta gtaaatgctg gagttggtac atcatttgtc ataaatgtat acgcggcaca
    29161 ttcaaaatta taaactgtgc ctcccccagt atatacattc atcatttcca tagcaatcat
    29221 tgattctggt tccgatgcat aggatctcat atccctagct cttccagttt caaatgtgtt
    29281 tgtataatgt ttttcccacc atttccatgt atctgttgat gagccccagt tatcacataa
    29341 gccactcaac caaaatccac taacgataga atctgtaccc gcatcatctc ttattggcgt
    29401 atttttagtt gccaacacca aatttttatg atatttttga ctcgcttcaa agaatgtcgg
    29461 atcattcata atagtttccc agaaccattt ttcatgatca tgccagataa aatgcgctcc
    29521 atatttggca caaacttcca aatatttagc actatgcgga gctaactggt tattgtaaat
    29581 ccaataattc tcaatattta aaacaccttt taacacacta tacttttgga attgttcatc
    29641 taaccactct ggaggaactg tattacgctc tccagccgac ataataacca agaaaactgg
    29701 aatgtttaga ctttgagctt cctccaacat cttgacatac cattctctca attctttcgt
    29761 atctcgtgga atacaacttg ttggtttaca gacttttgca ggatgaagtt caatcgctgc
    29821 atatggtttt acatcttcag gaatagcttc ccatgctccc ttcaatgtgt tcccccacca
    29881 taatccgtta ccattatcat tgccatacaa cggagaaagc aacaatggcg attcattatt
    29941 aatcgtcgtt ctcatttgaa cacgattatc agccttaact cctgctaaca atccaaaaca
    30001 taacatccca atacatacaa acagtattgt gattaatttt ctttttattt tttctttatt
    30061 catgacttat acctaaaaat ttaactcaat aattttttct gaattaaata ccaattcaat
    30121 attttgtaca tcagtatttt tgccatatat tcttactctt actttttgat ctttgtttcc
    30181 tccttccaat tttaggaatg ttatatcccc atttttccaa gcaaacgata ccttatatcc
    30241 tcctcttact ctgaaacctt tcacttctcc ttctgaccaa gcagaaggta aagctggaat
    30301 tagtgataac caattatgat ggctctgtac taataattca caaattccac tcaccaaacc
    30361 taaattacca tcaatttgaa atggtggatg gtcaagaaat aaattgccaa gagtcgcatt
    30421 atttaacaaa ccattaatct ggttataagc aggttcacct tgatatagtc tcgcaaaaaa
    30481 atgaatcagc catgcagcac tccaacctgt ttgtgtacta gcatgcaaac cacttactaa
    30541 ccaattatta atcgcttgct ccctctcctg tgaagataaa aagttagcgt ttgataatct
    30601 cctattgata gtgattttag ctgcttctgc taattccgga gttttatgaa tatcaatctc
    30661 attataagga taaagcccaa atagaggtga aatgtgtcta tgcccaggct ctacttcttc
    30721 ataatcttct aaccattctt ggatttgccc attactacct atttttgttt taggtagttt
    30781 cttttttaac tccttcacac gactaataaa atccgaattg tctcctaatt gttttgcaat
    30841 gccaatgcat gaatcacaaa aatatcttag aatttgatta tcaattgtag atgatagaca
    30901 agcatttcct tcaataccat tttttaagcg atatttattt tccggtgaga cacttggacc
    30961 tgtcatcaag tagccatcca cctcaaataa ataatcttca aagaaaagaa atgcttcttt
    31021 tatcatttca aaatgttccg taagaatacg ctcatcttgg aaatataaat agtgttccca
    31081 aatatgagta cataaccatg gaatagttaa tacccaaatt gcagccccca tggcatgaga
    31141 ttggggagcc gtatcgccaa aaccatccgt attatgatgt gctgtaaaac ctctagctcc
    31201 atacattttc ttagcggtta gtcttcccgg ttctctcatt ctttcgagca tatcaaataa
    31261 tggatattct acttctggta aatcacatgg acctaccatc caataattca tttgagtatt
    31321 aatattaatc gtatatttag aaccccaaat tggatttaat tcatcacacc atattccttg
    31381 aagattgaca ggtaaaccat tcggttgact agacgatatt aacagatatc ttccataatg
    31441 aaataacaag ttagtcaagt agttactata ctttttagtg ttttcaagaa gtagattcgt
    31501 tggaatgcta agacaatctt tactatagtc tagtttaaaa tcaactctat taaattgctc
    31561 ctgatatttt tttacatgtt catctttttc tgtaaagtaa tcaatactac taaattctcc
    31621 ctgaagagaa gaaatatcta tatttcccca ataatccgtc attgatttga gataaagaaa
    31681 tacctctgta gcattccgaa taactattgt ctctcccaat acacttactt caccatccgt
    31741 aactttagaa tgacatacta ctttaaactg aacacctttt ctacctccag cagaggccga
    31801 cattaaaatt gtacttgaat ccagtttaga tacttcgtca ttaaaccgtt tatttctacc
    31861 caaattaatg tttaaattta atgtgttttg aactgatgac actatacggc aacataaaat
    31921 attcttatta aaactcgtaa aatattctct ttttatttgt aaattacaac tattaggctc
    31981 aaacacaaca ttagaaatag ctgtatctaa atctagctct ctttcataca atgaaagagc
    32041 acaagactga atatctatat gctcaatgta aagttcccca agtaattcat agtggctttg
    32101 atctcttggg gtagcaaaca ttgttaactt tatcaattct tcggctttct gaatttctcc
    32161 atctaaaaga tattcccgaa tttttttaag atgcaatagt gagtctggat tatttctatc
    32221 tgactttcct ctataccaaa tagtctcatc gtttagttga atacattctt ttgtagctga
    32281 accataaatc ataccaccta aatgaccgtt cccaatcggc aaggcttcat tccaatttga
    32341 ggcagctttc ttataccata atttcactct ttacctctct tccaaaatgg aggtgatatc
    32401 ccaaatacca cctccacact ttctactact tcaaaattcc taaaacaact aggataactc
    32461 caatagccat aacactaaag attagtacaa ccggattctt tccttttcta attaatttac
    32521 acattaataa agtcaaagcc atagggataa atcctggaat taattttgta atcatttctt
    32581 gaacagaaat aacaagttcc ccctgcttaa attctaatcc aaaattaata ccaaccattg
    32641 atggaatcaa accacccact agtactagcc ctaatgctgt cgccatactc gtaacgcgat
    32701 tcaatgttcc ttttgtatta ttttcttgga taagactaga acccttagta tacccatatt
    32761 tcaaaccgaa atatttaaca ggaatattaa taatattaaa caatattaag gcgataaaga
    32821 tacctaaagc accgccgtct ttagaataag acgcaccaat actaaaacag ataggaacta
    32881 gtgtcagcca gaacaaacta tctcctagac cagccagtgg ccccatcaag ccaactttaa
    32941 taccagtaat tgaagctgca ccttcatttc cttcttgttc ttccatagcg gaagtaactc
    33001 caagaataaa tggtgccgct gtttgatgag tattgaaaaa ctcaaggtga cgtttcattg
    33061 caggagaagc tgaatctttg tctgggtata gttttttcaa tactggaaga attgtatata
    33121 gaaaacctag gttctgcatt ctctcatagt tccatgaaga accatacata aaacttcgtt
    33181 tgaaaacttt tttaagttca actttagtta ctttattatt catcatagat caagatcctc
    33241 ctcaacatca ctacttgaag ttgtttcttg tggtttactt ccaatcatat cgtagaagta
    33301 tgctaccgca ataccaacta gtgagatccc aatggttgac attcctccat acacagaaca
    33361 aatgaatcca atcaacaaga atacccacat atttttcttg agcatcatat ttaaaagcat
    33421 accaaaacca attgaaggta gtaaagcacc tgcagagtta agtccctgca taacgattgg
    33481 tggaacctta gcaaacaagt ctgccacata ttcccctcca agcataatag ctaggaaaat
    33541 tggtacaatt ttaaataaag tgattaaaac caaacttgaa taatgataaa aaccgatctt
    33601 tgaataatct ccgtttttag catcattatc agcttttttc acaaaataaa catctaaagt
    33661 ttttgcaaga acatccaact gttgagtagc aactgcaatt ggaactgcta tagcgatacc
    33721 agcagtttct ccttgaccag acaaaatacc aaatgcagta ccaataatcg cacctgaaat
    33781 agtatctggt ggagtgtaac ctccaatacc tgttacaccg agccaagtta attcaagagc
    33841 tgaaccaata agaacacctt gggtgaaatc tcctaagact aagccaacca ttgcacttgt
    33901 aactaacgga cggtgaatca taaataacgg tccattatag tcaatagtgg caataatccc
    33961 aactaatgtc accagtaatg cttgtgtgaa tagcatatac tgtacctcct taaattattt
    34021 ttataaaaat ttttccaaca ttgtaacttt atcattagga accatttgaa tttcaactct
    34081 cgttccctta tcaactattt tcttaaaata atatttgtct tcttcaccta gagctacacc
    34141 tcccgttacc ttttcatttt cctccgtttt actcatctgt cctacattga ggtactccaa
    34201 ttttaaattt ccttcaatag aatcatacac atcttttgga tttgtatata tcagcattgt
    34261 tctctttttt attggcacag agtttaaaac ttccacaaac cgttttacac taaagaaaac
    34321 aatttttaaa cctaccggtg cagaaatctt taaaatagat tgtcgtgttt tatcttctga
    34381 gatgcgatca ttaacaatga taacttgctc aatatcatac ttttttagcc acgtagtgac
    34441 aacttgacca tgtaccagac ggtcatcaat acgaacaaac tctataggca taaatcctct
    34501 tcctcctcta cgttaagttg ttgtttaaca ttaaacaaac tattttgagc attttgaaca
    34561 atttcttcta aattgatttt tgaatcataa cttgatatta attccactag gagagggata
    34621 ttaaaccctg ttacaatatc aactgaatcc aaatttaaaa accgtgacaa agccacatta
    34681 ttaggacttc ctccaatcaa gtcagtcaaa acgataacct cttgatttga gtctaacagt
    34741 tcatttactt gatttttaaa ataatgttca aactctacaa tattctctcc aggcatcaaa
    34801 cctaatgtcc taactctatc atttgttgtc tcaccaacaa acatttctgc ggtcatgaga
    34861 gctccgctag caaaattacc atgactggca actaaaattc ctctattaaa cattttctct
    34921 ttcaacaact actcctttct taaggataat attagcataa agtgaagttt ctcctgtagc
    34981 aacaatagca taagctttct tactacgttc ataaaagtct tctcttctaa gataagtaat
    35041 cgttttaaga tctgtaccat gaccttcaat catctgtcta taggtacccc atatcttagg
    35101 aatatcatca cccgaaacaa cgttcataaa ctgaattgaa ctatcgacgt aactatctaa
    35161 tggcattaaa tacagaatgg aatctaataa ttctggaata tttacaccat cacaacgaat
    35221 tagcttattt gcacatgagg cagaaggata attcgcgtca gctaatacta tttcatctcc
    35281 atgtcccatt tccattaaag tcttcaataa atctggagaa atatttttcg gtatatgttt
    35341 taacattaat atcctcccta ttttctctga ccgtatgttt taaatttttc tgccatcaat
    35401 tccatctcct catcaggaag aactactggc tctccaaaat tcttagctaa acaataaatt
    35461 tttgcacaat attcaacttc ttcaacaata ttaaatgcat tcaataaatt ttgtgcacct
    35521 gctaaaattc catgattcgc tagtaaaact gctctacgac cttccattgc tttagctgca
    35581 ttcacagcca attctttcgt gccatatgtt gcatactcag ctacccgaac atctttccct
    35641 gccactgcaa tcatataatg actcgctgga agtggttctc tgagacaagc taatactgtt
    35701 gcataagttg tatgagcatg gataattgca tcgatatcat cacgagtttg atattgaatc
    35761 aaatgcatat accattcgct agatggcaag cgttctccct ctacaacatt tccattaata
    35821 tccatcacta caatatcgga ttctttgatt tcaaagaaat caatacccga cggggtaatt
    35881 gccatcaatt gtttttcacg atcgaaaacg ctgagattcc cacctgttcc tttcgtcaaa
    35941 tctgtttcta ctagcttctt accatattta attaattctt gttttacatc tgacatcctt
    36001 gtcctcctca tatcaaaaca ctaaatattt ttcaattcac caattatccc cccttcctgc
    36061 acaaaagcta agaaggggga gggaggcaaa tttacaaact ctcaatcttt ttaattcttt
    36121 tgggagtaat aactctctaa ttgtagaaac tcctcaataa catggtgagc ctcttccatc
    36181 ccttttaatt gtcccatagc tatgagctgc acaacaatat tccccacagc tgtaccctca
    36241 gtcaaacctg taagaacctc tttaccagtt ctatcagcaa tcatttggtt aaagtaactg
    36301 gctctagcac ctcctccaat cacatatatc ctcttataaa ccttatgagt tagttcttct
    36361 agtaactcta tcgctttcct atacgtttca gctaggcttt cataaacaat cttaaatagt
    36421 tgtccatctg tccactctct agtttcatga tgataaacta gatattctgt caaagtcttg
    36481 tgcatatcag attctgttgc aaattcagtt gattcagtat caatcagagg aagattttct
    36541 ttttctttct ccaccattgt cctaatatca tcaaaagaat aggctttccc tcttcgttca
    36601 aatgaacgtc ttagttcctc tatgatccac aaccctgtac aattcttcag aaatgtaatc
    36661 actccatctt taccgacttc atttgtaaat ccataactga aggattcggt agtaagaatc
    36721 ggtgaagtaa gttccactcc aaccaaagac caagtacctg atgaaataaa taaactacct
    36781 tctgtcttag gtactgagac aatcgcgctt gctgtatcat gactacaaac attcacaaca
    36841 ggaatatcgc ctaaaccata ctcctctttt atccttccaa gaacatttcc ctctgaaaca
    36901 atttcaggaa gtaaagttga atccaattca aatagtttta agatattctg attccaattt
    36961 tgactcctag gatcaaataa ttgagttgtt gaagcaatgc ttttttctgt agcaaactta
    37021 cctgtcaaga gataattaaa caaatctggc attaaaagaa tcttattggt cttatagaaa
    37081 gagtcaggag attcttgacg tgccttaaag agttgaaaca aggtatttat ctccataatc
    37141 tgatttcctg tctctgaata cagtttttct aattcagtca tttcagatat ttcctttaac
    37201 actccctttg ttctttcatc acgataatga acaggttgtg ataacagctt accttcatta
    37261 tcaatcagtc caaaatcaac tccccatgtg tcaataccga tagataaaat cttgtaacta
    37321 gtattagcca agcggatact ttcaagaatt ttagctagta gaaagtcaac atcccaagat
    37381 aaatgccctt ttactctaat aggtagatta gaaaagcgat ttatttcttc cattactagt
    37441 ttattttcag aaaggtaacc aacgattgct cttccagaag tcgcacctaa atctattgct
    37501 aaaaccgctt ccatttttct tctctcttcg tccttgatta actttattat aatccccacg
    37561 ttttattttt tcaatatgtg aacgcttact tgaataatgt tcaaatgtta acccaatatt
    37621 cataaaaata attcacattc ctccaatttg tgctataata tagttgaaat gataaattag
    37681 gaggagctta tgataaaaga tgaacgtgta cttgaattga ttgaaatcat caaaaagaaa
    37741 aaaagaattg ccgtaaaaga gctggcagaa atcactttct ccagcacaag taccttacgt
    37801 cgtgatttaa ttttcttaga aaatcaaggt cttatcaaaa gaaagcacgg atacgtgacc
    37861 ctgtcctcta tgaacacaat tgaactttct catcaaatac gggaaggaga aagtactagg
    37921 caaaaaagac taatcgctag tctcgctaaa gactttattc ggtctggtat gtgtatctat
    37981 ctagattcta gtactactgt ctacgaactt tgtccctatc tttctgaact tgataatttg
    38041 attattttta caaatggttt acatactgca caaaccctat ctgaaactgt taaagatagc
    38101 tccaaaatct ttatcacatc tggcgaggtc aaacatcaat cctgttccgt ggtcaactat
    38161 gataaggaaa attctttatt agatcatttt aatatcgatt tagcattttg ttcagcaaga
    38221 ggtattgatg accaatatgt ttatgaagct tctctcagcc aagctatttc aaaaaagaat
    38281 attattgaca aagcccatga aaccatctta ctgattgata gttctaaatt ttacaagact
    38341 ggatttttta aaattaatcc cctatccaaa tacacaacct ttatttctga caccttgcca
    38401 gaccaaaaat tattagacgc agtcgaatta tttgatggag aatgggtttc tgatattcaa
    38461 taaaaatcaa ataggaagct agtctcagct tgctcacagt acagatttga aaactgatga
    38521 agtcaaggcc cccatggaca cggcaagacg aagctgacat gatgtgaaga gattttcgaa
    38581 gagtatcgtt ctgtctgctg actgatttac aaatattcac cacatgacat tattttctta
    38641 gcaaccctaa aaacagaggc tggacaaaaa ctcaatttca ggagaaatgg ggcaaatatt
    38701 cccacaataa aacgcatagt atcaagtttt tgcacacctg atattatgcg tttttctgat
    38761 tttaaagact ttgtcgccta gaccctatat ttcaagaatt aagtgacctt gatgatctaa
    38821 atgtattgtg gtatactatt tttgtcatcg gttaccgatt acgttcctat gggttcgtga
    38881 gaggaggtga aactaatgag ccttatcata gagctcgctc ttactattat agcggatgtt
    38941 atagctggaa ttatcttgta tttcgtctgc agatggctag atagtaagga gtagaccgac
    39001 tgactagcct ataaacaccc gttaaatcgc taagatacgt caaaaaagcc cttaactacg
    39061 gccatagtta ggggctttgg tgttctaatg aaccttatca attaactaca ttttagcata
    39121 taagtcctaa tatttcaagc attaagcaat gttgatgatc taaatttaat gtgatatact
    39181 atttttgtca tcggttaccg attacgttcc ttacggttcg tgagaggagg tgaaactaat
    39241 gagccttata ccagagcttg ctcttactat tatagcagat gttatagctg gaattatctt
    39301 gtatttcgtc tgcaaatggc tagatggtaa gaagtagacc gactgactag cctataaaca
    39361 cccgttaaat cgctaagata cgtcaaaaaa gcccttaact atggcactag ttaggggctt
    39421 tggtgttcta atgaacctta tacactaact acattctagc atataagccc agatatttca
    39481 agagttttat ttattttttc aggttccctt agttctgaaa ggtctataat gaagttagcc
    39541 atctagtatc aaaaaaccga ctagctctta tgaactagtc gatttctcat caatgcgcca
    39601 acatttcttg agcgatttct tggccagata ggttatctgg gtagtaggtt ggccagttgt
    39661 ccatttcttc aaagagggct tcttggcttg tgcctccaaa gaagatatgg aaatgttctg
    39721 ccttaactgg ggcgatattg tggtcactaa actgaacata cttgaattgt ccagcgtcag
    39781 catctgtggc ttcaaagagg aaacgcacgc cacgattgcc tttcttgtaa gtcaaaattt
    39841 tcttaccgac atacttgtaa gtatatttct tgctttgtcc accttgaaca aattccatag
    39901 tattatcagt aatgttaatc ttagtcacat ctgtctgata gccttttgta tagtaagcct
    39961 tgtactcagc ctgggtcatc ttaccagtca acttagcctt gtagtcaaag acttggtcaa
    40021 acgtgccgtc ttcaaggaaa ggataaactg attgccagtt acctgcatag tcactcaagg
    40081 tgcggtcctt gacagctgca tcctcgaagt aaccattttg gactgtcttg gtatcctctg
    40141 ccttttcagg ctcgatcgct gggccttctt ggtctgttgt ttgtttcaaa gccttgaggt
    40201 ttttctccat gatagagatg taattttctc cagccttggt gtcctcttct gtcagacttt
    40261 ctaaaggatt gaggacatca gttttgacac ctgcttcttt tgaaagtgtg ttagcaaggg
    40321 cttgtgaggc attttcttca aaatagatat aggcgatttt atttttcttg acatactctg
    40381 tcaattctgc caagcgagca gctgatggct ctgcatctgg agaaagtcct gagattgcga
    40441 cttgtttgag tccatagtcc aaggcaagat agttaaaggc tgcgtgttga gtcacaaagc
    40501 tcttttgttt tgcttgagac aagccttctg cgtaagcctt atccaaggct tgcaattttt
    40561 cgatataggc agctgcattc ttctcaaagg tctctttttt atcaggataa tctgctgaca
    40621 agctgtcgcg gatgtgctct actagtttaa tggcacgaac tggtgataac caaacatggg
    40681 ggtcaaactc atggtgatga ccttcttctc catggtcatg gtctccctct tcttcctcgc
    40741 cacctggcaa gagcaacata tcgcctgtcg ccttgatggt tttcactttt ttcttatcca
    40801 aggtatctag caatttaggt acccatgttt ccatgttttc attttcataa acgaaggtat
    40861 ctgcatcttg gattttggca actgccttgg cagatggttc gtattcatga ggttctgtcc
    40921 cagcaccgat taggagttct acattagccg tatctcctgc gacttgcttg gtaaattcat
    40981 agacagggta aaaggttgtc acgatattga gtttaccatc tgcctgtttt tgattggaac
    41041 aagccactaa aaacaaggca catagactgg ctagtaataa gctaattttt ttcacgttcg
    41101 tctcctattt gataaaacgt cttactaaac tgattagtat aaagacagtt acaaaaataa
    41161 tggtaatact tgcacttgca ggtgtttctg catagtagga aatgtaaagt cctgctacca
    41221 ttcccaaaaa gccaatcgca ctggcaagca gcataaccga tttaaagttt ttccccagac
    41281 gcagggcaat actagctggc aagaccataa tggtcgatac cagaagagct cctgctgcag
    41341 gaatcataag ggcaatagcc acccctgtca ccatgttaaa aagaatggac atggtacgaa
    41401 ctggcaagcc atccacaaag gccgtatctt cgtcaaaagt taagatatac ataggacgaa
    41461 gaaagagaaa ggtcaaaatc aaaacaaccg ccgcaatgac aaagagggaa atgacctgtt
    41521 cttcactgat agtcacgatc gaaccaaaga gatattggtc caaactcatt gaactcgagc
    41581 ttttaccctt gctcatgaca atcagagaaa cagccaaacc tgttgacatg aggatagctg
    41641 tcccgatttc cataaagctc ttgtaaaccg tacggagata ctccagaaag accgccgcaa
    41701 tcaagacaat ggcaatagta gaaacagttg gagaaatccc caaaaccaga ccaaaggcta
    41761 cacctgaaag tgagacgtgg ctaagggtat cactcatcaa actctgacga cgcaagatga
    41821 ggaaggttcc caataccggt gagaaaagac tcatagcaat aaccgccaaa aaggcgcgtt
    41881 gtataaagtc ataagataat aaactaagca tggcccacct cctgcccatt ctcatgaacg
    41941 ttgaaacaac gccatggcga gtcttggtta cggactagat gaatattgcg atccgcataa
    42001 tccttaactt cttcagggtc atgggtaatc atcaaaacag ccttgccatg atgatgggcg
    42061 ctgtggtgca tgagttcgta aaattcattt ttacttcctg catccatccc cgttgtcggc
    42121 tcgtctagga taaacacatc agggtcagaa gcaaacatac gcgcaatcac cgctcgctgc
    42181 ttttgtcccc cagatagaga ccccaagcgt ttgtctcgat gttcccacat gccaactgag
    42241 tccagactgg ccttgatatg ctcctcatca tgagcattca aacgacggaa ccagcctttt
    42301 ctcggatagc gacccgactt gacaaattca tagaccgtac ttggaaaacc agcattaaaa
    42361 ctggcaattt gttgaggaag ataggctatt ctcaatttct taccttgcgt atttgtcttt
    42421 gaaatagcca cctttccaat gcgtggttgc agaattccaa gactggcctt gatgagcgtc
    42481 gtcttagccg ctccattttc cccagtcaag gtaacaaatt ccccactatc aacactataa
    42541 ttgatatgtt caagaacagg ctccttatca taatagaagg acaaatcctc taccgtaata
    42601 tatctcatta tttgatttct cctactaaag cagtcaaaaa ccgctgaatc actttttgtt
    42661 catttggagt aaactgagtc gccacttgtt cataggttaa aagtgtatgc tcatggtgat
    42721 ggtggtgctc ctcagcgatt ggacgagcca agtcagtcaa ctgataaaaa atcacacgcg
    42781 catctttaga atctttagat gtttccaaca tcccttcctt gaccaaagac ttaatggcct
    42841 tggtaactgc cgcctgactg acattgagac gacgggccaa ttctgaattt gttaaagatt
    42901 cctctgacaa gagcataagg atatgctcct gagtattggt cagggccacc tcgctagtgc
    42961 aatgacctat taggatttca tgctgatttt ccgcctgcaa aatcacctca ttcaaaaaag
    43021 cattgatatc ctttgctagc tgtctcatat ctgactcctt tccttttaga cttctctttt
    43081 ttaagagaaa aatactattc tttgacattt tgtttaccag ttaattatat cacaagcaaa
    43141 aaaagagtca agaaaaaacg tgaaaactag tttcattctt gaactcttct atattatatt
    43201 atctattgaa attctttgac atctccatca taagtcgccc aatctttgct gaaaaagcgc
    43261 tcattcagat ggtaagtcgg agctggtgtg ggattggata ggaaaggatc aactgccttg
    43321 tcaaaagcca accaacccaa ccaaccaagg tgaatggtgt ccttcataaa gaaaggctcc
    43381 ccaccgtcct tagaaaaatc tgctatattg gtaaaacctt gactttctaa ctggtagcga
    43441 atcttctgca ccgtttgttg gtacatatcc tctcgtagac cagcatagtc catccatttt
    43501 ttattaacag gtggaatgat aaaaatcggg tttaccttag atttagaaaa ctgtgttaaa
    43561 accaactgca agtcattata ctctggcgac ttgagatagg taaagctttt ctgagaatcc
    43621 tttaatttct tcaaatcctt cttgatctgc tcattataga aataattttc cattcccatc
    43681 tcattattgg aagtattttt ttcagcatct gctttgacaa catcttctat tgcttgataa
    43741 gaaaactggt ctggcaagat ttttaaatac ttagctacat gcttatcgta gttaacatag
    43801 cctctaaccg aaaactgacc aaaaaaggag gcttggcgtt cattaaaacg agccaataat
    43861 tcaatcattt cattgtctgc tgtcgacaat tcttctttac ttgccaactt ctgaaccagg
    43921 tccttcatag ctacgtttgg gaactgttgc agtaagcgag tcgctgcata ttgactagcc
    43981 tgatccccag attgatgttt cagaaaacta gtcaactggt ctccattaaa atactgctgg
    44041 aaggctgctg gatcatagcc atttttactg aaccactgag gtgagataac atacacaact
    44101 tgtttattct ccagctgtgg taacatctgt tgcattccaa aatattggtt aagcgatgca
    44161 gctcccccct gtcctaaaag ataaggacgg taggaacgat tgtatttctc agctaatacc
    44221 gcaggatgag caccgtcaaa acgaagccat tcactagagc caaagaaggg aacaaaacgc
    44281 acatttggat cagatagtgc tctgactttt tgacttcgct ccttaaaact atcgatagta
    44341 gtagccactg ctgaacgctt ttcagctcct agattatgat gcatctcagt aggataaaag
    44401 aaaatgagca gaaaaaccaa caaaccagcg atcaagaccg gtccgaagat catccataag
    44461 cgtttaagca ttttgtagct ccacaatacc agctatgatt ttattagctg tattccagtc
    44521 gtcacgacca aactctgtta cagggacacg aatgtcaaaa cggttctcaa tctccacaat
    44581 caactcaacc gttcccatac tatccaagac acctgcatca aaaagatctt catccatcat
    44641 gtcagaaaca tcttccataa acaactcatc aataatttca ataacttctg atttgatatc
    44701 catattttat ttccttttat tttttaaacc atagattatt caagaatcca gaaaagatta
    44761 agaatgacaa catgacaaca tggaaagtga caaccatgcc aagcaactga atccagcgat
    44821 tctcaggtag ggcagccttc cctgcttttt tccgttcctt attgagcgtt tttttcttgc
    44881 gaacccaggc atcattgatg accaagccta gtccatgaaa gagtccatag gcgatatagt
    44941 accaggtcac accatgccaa aatcccataa tcagcatatt tacaatgtag gccatgcttg
    45001 aggttacatt acgattttta aagactttct ttctggttaa caccatcacc attcgcataa
    45061 agacaaagtc acggaaccag aaggacagac tcatatgcca gcgattccaa aactccttta
    45121 aatcccttga taaaaagggc ttgttaaagt tgatagggct acggattccc atcaagtttg
    45181 agatggccaa agcaaacata gaataacctg caaagtcaaa gaagagctcc agaccaaaag
    45241 tatacataac tgccaaggca tagagattaa agaagccacc tgactgcaag gctaaattct
    45301 tcagaggagg tagtaaggtc tctcctaaaa catgagctag gataaactta tacaaaaagc
    45361 cccacatgat atagcggaca gattcatcca gcatatccat caactcatct cgctcaggaa
    45421 tagcctgata attttcatta aatcgcttaa agcgatcgat tggaccactc gagaaagttg
    45481 gcatgaagag aaggaaacgg aggaattccc agagggtaaa atccttaatc actccatctc
    45541 tcagctcgat gataatccca accgaacgaa aggtcaggta agaaattccc aagaacccaa
    45601 gcaaagactg cgttccattg atagctggtt gcaccttgac aaagataatc ggaagtaggg
    45661 acagaaaact aactaagtag aagacccact tgccatcctt gctttttcga taatgcttgt
    45721 agaaaagcag gagcaatatt tcccagcaaa ggtaaatacc caaggcagct agttgattgg
    45781 tctttccacc caccaacatg gtgacaataa agaagagact taccaacact tcataccagg
    45841 caaagcgttt cttgaaaaag aggcctataa agatgggcaa ggttgcagca atcacataaa
    45901 caaaatactg aggattgcca tatggctcta aatgaggaag ctgttgaaaa aactccatca
    45961 tctcttattc acctcgttaa tcaatccttt gatgtcaatc tttccatttg gagttagtgg
    46021 caaactgtct cggtaaagga atttagatgg catcatgtag gacatcatga tgtctgtcag
    46081 gtcttccttg atggccttgg taatatcgat atctcgctca aactgctcac gaacaccgtc
    46141 ttttaagatg acataagcca atagattttg taccttgtgg tccttgttat agcgcggtac
    46201 tgcgacagca gattcgataa agcgagactt gttgaggttt tgagagacat cttctaactc
    46261 aatgcggtaa ccgttaaact taatctggaa gtccatgcgt ccgccgtaga gaagcaagcc
    46321 ctcatctgtc atggttccca catcgcctgt gtgataggct ggcagacctt caaactcaaa
    46381 gaaggcttct gctgtttttt caggattttt catataacct tttgaaacag ctggcccaga
    46441 aacaatgatt tctccctgct caccatttgg cagtttattt ccttcctcgt caatgataaa
    46501 ggttggagaa tcagccttgg tatagccgat tggtaggcgt ttgagagtcg ctaacatctc
    46561 gtctgtcacg gcaactgctg acagagctac tgtcgcttct gttgggccgt aagcattgat
    46621 gatacgggca tttgggaaac gctcgcgcag tttttgagct gttttgaccg tcaattcttc
    46681 accatcaaag tagaaatgcg tgattccaga cattttctca ctgttgaagt attcagacaa
    46741 catggccata tctgcaaagg atggtgttga tgtccagata gcgattggca atgaaaagat
    46801 agccgcaaag agttgcttaa agtcctgagt gatgactgaa ggaagagtga aaagcgtacc
    46861 accaagtgcc aaggtcggtg cccaatacat gacagacaag tcaaaagaat aaggtggctg
    46921 tgccagcatt tgcggacgac tcggtgtcgc aaattcctta tccgtaatca tccagtttgt
    46981 aaagctgagg agattatcat gtgaaatctg cactccctta ggcttaccag tcgtaccaga
    47041 agtaaagata atgtagtaat tatcatctcc cttgactgga tgcgtgattt catagttgtt
    47101 cccttgggca aaggcttctt gaacctgagc tagatttatc attggtgtag aaacctgctc
    47161 caagggaaag gctgaaatgg caataatcaa gcttggctct gctacttcta aaatagctga
    47221 aactcgctcc aaggccgaat ggctatcaat tggaatgtag gcatgacctg acttagtcag
    47281 cgctacaaag gttgccaaca tttcatattc ttggccacca aaaacaacca caggagactt
    47341 ctcaggcaag cctagttggt caatgactgc agccaaacta tccgaatcag cctttaaatc
    47401 gccataagtg tgttcctgcc ccaaaacatt atagacagga tagctaggct gtgtctgagc
    47461 aaaatgctca atggtttcaa tcatatctgc tattggttta tttgacacaa tagggattct
    47521 ccttcaagtt aaaattcatt atagataaag cttccttgac cctgaccaag atagctaaag
    47581 aagtaaagca gccctagaaa gataagaaaa tacaaggctg tccgaccaag aaagaggtac
    47641 aattcttttc tctgtttcat caagaaaaac cattcatttc tgtaattttt cgctaaaata
    47701 agagtgattc ttactagctt atttttctac cattgtacca ctttatatag tatcttttca
    47761 attgtttacc gtatgtttcc aatagatttc agcttatttt aaggattata cagtttttct
    47821 atgtatattt tcaaatagag tgatcctgct tcaaaactcc atttcaggag acaatgaagt
    47881 aaatcttccc ataataaaac acacaatatc aagttttttc aacacctgat actatgcgct
    47941 tttctgattt ttaaagactt tttaaccact ctctcattta aaataatctc gtctgatata
    48001 aattaaaata gcttctatca tcagacaaat ggctgatagc caaaaactga tgctaatacc
    48061 aaaactctca gtaatatagc tcattagcaa aacaaatact gaaaatgcta atgtagaaat
    48121 cacttcaaga acggaataga cattaactaa atgattttcc tctactgttt cctgaagaaa
    48181 tacactttca ggaacttctt ttagttgcga taacatacca actaaagctg aaaataataa
    48241 aaacatctgt gcgtttggaa aatatagaat agtcagtgtc actattgcca tagctacaag
    48301 aggaaaaaga atactttccc atttagcagc aaggaacttt tcagatagcc taaaagcaat
    48361 taagccacta attataatac caatagagta tgctgtatta gaatatcccc agtaactttc
    48421 cgttttattt aataactccg ttacaaaaac aagtataatg gaagaaaccc aaatcgtatt
    48481 tgaaaaaatt tccaataaat ttgctgatac aaaaagtctt aatctaggat ttctagcaac
    48541 taacttccaa cctttgagca aaatttcaag attagtttct gactctaaca cctccacttc
    48601 agcgttagga agaaataaca tcagaaagct agaaatgata tacaagacta aaatgataaa
    48661 cgtggtaggt aacagaccaa ttgttgcaaa taagagtcca cctaatcccc aacctatcaa
    48721 ttgaacagct tcaccagtca ttgataaggc tgaattagcc ttacccaaat cggtcgcata
    48781 gcgtggcaca atagcatagg aaacgggtgc tgcaaaacca tctagtatgg aaattgcaac
    48841 aacaaataga taggtcacca aaggcgctac ggattgcatt acggtaaaca ttcctaccag
    48901 tatcgccaat aatatagtct ttccaaattg agataaagat aaaaccctat ttagcgctaa
    48961 ccttttagta accaacggaa ctaaaagact cgcaacaaaa gaggatattc ctattaagat
    49021 aggaactagt gatgtggcaa ttactgattt tgaaataatg tatatgttag caatgattgt
    49081 tactctaaag aaaatatctg ctaaatttgc aaataattga gagactaaca acttgacaaa
    49141 tgaattagac atgtagcgct ccccctttag ttacaaactt tggaattaaa tttgattttt
    49201 aatattttag cataaaatag cagaaaacaa aagtgaggtt ttttacatga aaaaacaaaa
    49261 actattgcct ttattattcc taattttagg aggaattatg attatcgttg ttggctagta
    49321 ctaagaagtt agttagttag tagaataatt acatcttcaa tcgaaaaaga gactgggaaa
    49381 aagtcttaaa aatcagaaaa acgctcaaat cctttggcgc tctaagcttt tctaatgata
    49441 gattttagat agtcaaaaaa atatctgaaa agttcccaga tcgtcgtctc agcatcaaaa
    49501 atacgtgaaa tttgcataat taaaataaat ttcaggggag ttaatcgagt aggggataat
    49561 ctctagcccc tctcacacca ccgtacatgc cgttcggcat acggcggttc aactaacttt
    49621 taacgcatgt cgttcaaggt aataatccaa acacgaaacc agtccacgtt tttcaaggac
    49681 tggttttgat atagcacgtt taagtaccga cttctgagct actaattgat aatggtcgcc
    49741 ccagccagat accttatctg ctatccattt aggaactcct aacttaagca atccccatag
    49801 tcgtctcgat ttcttcttcc attgcttcca gataatcact cgtaggcgag tacgcaagcg
    49861 ctcatctatg ctagcgacta tgcgcttcat atttcccagc gagaaatagt ttatccatcc
    49921 tcgaatagac aaattcagtt gctcaatacg tcttgttaag tctatactcc atttcctctg
    49981 tgttagtttc ttcaatttaa gcttaaatct ccgaacacta tcttgatggg gacgactttt
    50041 ccaaccatct gatgatttcc agaacccaaa acctaagtat ttcagctctc ttggtctggt
    50101 aatcttagcc ttggtcatat ttactttcaa acctagtcgc ttctcaataa aacgactggc
    50161 tgaatacatc acacgcttag cggctgcctc gcttccgacc gtaatcacac aatcatctgc
    50221 gtagcgcaca aatcgaagtc ccctcttttc taattccttg tccaattcat taagcatgac
    50281 attggataag agaggagata aatttcctcc ctgtggcgtg ccaactagcg ttttatgacg
    50341 ctgaccatta atgataacac ctgaatgaag atacttacga atcagggatt ccgtatctcc
    50401 gtcttcgata atgttatgta ccaaggacat caatctatct tgaggaaccg tatcgaaaaa
    50461 tttctctagg tctatatcca ctatccactc atagccgtca tttaagtact ctaagaactt
    50521 catgatggct ttttcacatg acctatttgg tctgaagcca taactcgtat ctgagaaatg
    50581 gggttcacaa atggggctaa taacttggac aatggcctgt tgaatcattc tatccataac
    50641 tgttggaatt cctagttgac ggatacctcc gtttggttta gtaatctcaa ctctaagaac
    50701 tggttgaggc ttatattttc tctgttttat cagttcctta gtcaagcgcc agttttgtct
    50761 gagataatta tccatctctt cgatagtcat tccatcaatc ccagctgagc ctttattgga
    50821 ttttacttga ttgtaggctt ccagcatatt ttcgcgtgat aatatcttat ctagcaattt
    50881 tgacatgtgc gtattccttt cttgttttgg tgcctgaggg acatcttata ttggtgaacc
    50941 ttcatctagt cattacgtgt caaagtccag ttctatcaga ccactcattt tacagacaca
    51001 agtgaagtag gattacttcg atctgtcgtt ttctctttct agcgacagac ctcaaacagt
    51061 ctctccccag actgtttgag tattcacccc ttcgctccac ttccattacg gaagtttcct
    51121 cactactatg ggctcggctg acttctcatg attcgttgtt actacgcttt cagcgctcat
    51181 gaaacctcac gggataagtc gtacatcttt cctcgtttat acaagatatg aggacgttaa
    51241 aaggttacag tgaaaatagg aaatctgacg cagagtcttt agactctaga aagatttatc
    51301 tttttcacac aaaccttagt ccgaattcaa ttactctcgt gatttacaca tataggttac
    51361 gactaccttt ttggacttta gagtttgaag cctccttatc cgctatatac gccttgctat
    51421 cacgttcctg ttcgtagagc cacgatttcg ctatctcttc ctctgacgat tcttatttcc
    51481 tgcgtcagac ttaaaacggt ctatccccag accgttttaa tccgctacct cacgatagtc
    51541 aggcttggga atcgctattg ggttcaccgg tagcaggtgc ccaccgagga cttacacctc
    51601 agatatacga catgcc
//
LOCUS       DAVLDI010000008        49831 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLDI010000008 DAVLDI010000000
VERSION     DAVLDI010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49831
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.008"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            514..810
                     /locus_tag="VXD01_000432"
     CDS             514..810
                     /locus_tag="VXD01_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0600875.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPYNW
                     GAFSNYYHGSQYHWAYVGSNERDNQKTVYAGAHSAAYAFVNTNLGERITFDAGW"
     gene            913..2928
                     /locus_tag="VXD01_000433"
     CDS             913..2928
                     /locus_tag="VXD01_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0600876.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFGALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLTI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNFITSTEWHDY
                     SPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEDHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            2930..3562
                     /locus_tag="VXD01_000434"
     CDS             2930..3562
                     /locus_tag="VXD01_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0600877.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            3703..3981
                     /locus_tag="VXD01_000435"
     CDS             3703..3981
                     /locus_tag="VXD01_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HEV0600878.1"
                     /translation="MKKFDNYIIEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(4491..4904)
                     /gene="ndk"
                     /locus_tag="VXD01_000436"
     CDS             complement(4491..4904)
                     /gene="ndk"
                     /locus_tag="VXD01_000436"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV0600879.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(5015..8692)
                     /gene="rpoC"
                     /locus_tag="VXD01_000437"
     CDS             complement(5015..8692)
                     /gene="rpoC"
                     /locus_tag="VXD01_000437"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV0600880.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPTVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(8725..12336)
                     /gene="rpoB"
                     /locus_tag="VXD01_000438"
     CDS             complement(8725..12336)
                     /gene="rpoB"
                     /locus_tag="VXD01_000438"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0600881.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            12752..12822
                     /locus_tag="VXD01_000439"
     tRNA            12752..12822
                     /locus_tag="VXD01_000439"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12784..12786,aa:Cys,seq:gca)
     gene            complement(13020..14351)
                     /locus_tag="VXD01_000440"
     CDS             complement(13020..14351)
                     /locus_tag="VXD01_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV0600882.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVYQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELISQNKQFILTNDKVKNGRVTKVKIQITEVEIEEETE"
     gene            complement(14642..15466)
                     /gene="endA"
                     /locus_tag="VXD01_000441"
     CDS             complement(14642..15466)
                     /gene="endA"
                     /locus_tag="VXD01_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV0600883.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSNATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(15505..15693)
                     /locus_tag="VXD01_000442"
     CDS             complement(15505..15693)
                     /locus_tag="VXD01_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV0600884.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(15686..16969)
                     /gene="murA"
                     /locus_tag="VXD01_000443"
     CDS             complement(15686..16969)
                     /gene="murA"
                     /locus_tag="VXD01_000443"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0600885.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(16993..17223)
                     /locus_tag="VXD01_000444"
     CDS             complement(16993..17223)
                     /locus_tag="VXD01_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV0600886.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRV
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(17281..18318)
                     /locus_tag="VXD01_000445"
     CDS             complement(17281..18318)
                     /locus_tag="VXD01_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV0600887.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(18302..18790)
                     /gene="coaD"
                     /locus_tag="VXD01_000446"
     CDS             complement(18302..18790)
                     /gene="coaD"
                     /locus_tag="VXD01_000446"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV0600888.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDKLVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(18780..19319)
                     /gene="rsmD"
                     /locus_tag="VXD01_000447"
     CDS             complement(18780..19319)
                     /gene="rsmD"
                     /locus_tag="VXD01_000447"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV0600889.1"
                     /translation="MKIISGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(19384..20376)
                     /locus_tag="VXD01_000448"
     CDS             complement(19384..20376)
                     /locus_tag="VXD01_000448"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV0600890.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(20489..21172)
                     /locus_tag="VXD01_000449"
     CDS             complement(20489..21172)
                     /locus_tag="VXD01_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV0600891.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(21228..21968)
                     /locus_tag="VXD01_000450"
     CDS             complement(21228..21968)
                     /locus_tag="VXD01_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV0600892.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            22002..22280
                     /locus_tag="VXD01_000451"
     CDS             22002..22280
                     /locus_tag="VXD01_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV0600893.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22358..23284
                     /gene="yidC"
                     /locus_tag="VXD01_000452"
     CDS             22358..23284
                     /gene="yidC"
                     /locus_tag="VXD01_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0600894.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPLLLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFST
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(23359..24153)
                     /gene="pflA"
                     /locus_tag="VXD01_000453"
     CDS             complement(23359..24153)
                     /gene="pflA"
                     /locus_tag="VXD01_000453"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV0600895.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKQLMDTESYQDYMKRVHG"
     gene            complement(24279..25529)
                     /locus_tag="VXD01_000454"
     CDS             complement(24279..25529)
                     /locus_tag="VXD01_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV0600896.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(25596..26423)
                     /gene="purR"
                     /locus_tag="VXD01_000455"
     CDS             complement(25596..26423)
                     /gene="purR"
                     /locus_tag="VXD01_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV0600897.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(26690..27631)
                     /locus_tag="VXD01_000456"
     CDS             complement(26690..27631)
                     /locus_tag="VXD01_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV0600898.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(27621..28877)
                     /locus_tag="VXD01_000457"
     CDS             complement(27621..28877)
                     /locus_tag="VXD01_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV0600899.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(28879..29541)
                     /locus_tag="VXD01_000458"
     CDS             complement(28879..29541)
                     /locus_tag="VXD01_000458"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV0600900.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(29504..30160)
                     /locus_tag="VXD01_000459"
     CDS             complement(29504..30160)
                     /locus_tag="VXD01_000459"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0600901.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRLLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(30171..31049)
                     /gene="rsgA"
                     /locus_tag="VXD01_000460"
     CDS             complement(30171..31049)
                     /gene="rsgA"
                     /locus_tag="VXD01_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV0600902.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(31051..31923)
                     /gene="rsmA"
                     /locus_tag="VXD01_000461"
     CDS             complement(31051..31923)
                     /gene="rsmA"
                     /locus_tag="VXD01_000461"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV0600903.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(32054..32362)
                     /locus_tag="VXD01_000462"
     CDS             complement(32054..32362)
                     /locus_tag="VXD01_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600904.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(32355..32996)
                     /locus_tag="VXD01_000463"
     CDS             complement(32355..32996)
                     /locus_tag="VXD01_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0600905.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(32998..35028)
                     /locus_tag="VXD01_000464"
     CDS             complement(32998..35028)
                     /locus_tag="VXD01_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0600906.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMTN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVHLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(35105..35401)
                     /locus_tag="VXD01_000465"
     CDS             complement(35105..35401)
                     /locus_tag="VXD01_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0600907.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(35721..36620)
                     /locus_tag="VXD01_000466"
     CDS             complement(35721..36620)
                     /locus_tag="VXD01_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0600908.1"
                     /translation="MLIGQKIKEIRIEKGVSRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(36692..37252)
                     /gene="rnmV"
                     /locus_tag="VXD01_000467"
     CDS             complement(36692..37252)
                     /gene="rnmV"
                     /locus_tag="VXD01_000467"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV0600909.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLVGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(37252..38025)
                     /locus_tag="VXD01_000468"
     CDS             complement(37252..38025)
                     /locus_tag="VXD01_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV0600910.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(38321..38995)
                     /locus_tag="VXD01_000469"
     CDS             complement(38321..38995)
                     /locus_tag="VXD01_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV0600911.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKPETTLGVDKGGNTGSSD
                     ANANAGGGSQAGGPAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKDKQDEIKGAPL
                     SDKEKAELLARVEAEKQAALKEIENTKTMEDVKEAETIGVQAIAMVTVLKRPVAPNAA
                     PKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLVAATSGFALLGRKTR
                     RRKWNS"
     gene            complement(39258..39392)
                     /gene="rpmH"
                     /locus_tag="VXD01_000470"
     CDS             complement(39258..39392)
                     /gene="rpmH"
                     /locus_tag="VXD01_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV0600912.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(39537..40751)
                     /locus_tag="VXD01_000471"
     CDS             complement(39537..40751)
                     /locus_tag="VXD01_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0600913.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(40907..41200)
                     /locus_tag="VXD01_000472"
     CDS             complement(40907..41200)
                     /locus_tag="VXD01_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600914.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            41362..41814
                     /locus_tag="VXD01_000473"
     CDS             41362..41814
                     /locus_tag="VXD01_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV0600915.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(41849..43237)
                     /locus_tag="VXD01_000474"
     CDS             complement(41849..43237)
                     /locus_tag="VXD01_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0600916.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            43303..44265
                     /locus_tag="VXD01_000475"
     CDS             43303..44265
                     /locus_tag="VXD01_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV0600917.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVNTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(44471..45481)
                     /gene="ccpA"
                     /locus_tag="VXD01_000476"
     CDS             complement(44471..45481)
                     /gene="ccpA"
                     /locus_tag="VXD01_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV0600918.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(45906..46505)
                     /locus_tag="VXD01_000477"
     CDS             complement(45906..46505)
                     /locus_tag="VXD01_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0600919.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSVADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(46507..47604)
                     /locus_tag="VXD01_000478"
     CDS             complement(46507..47604)
                     /locus_tag="VXD01_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0600920.1"
                     /translation="MLERLKSIHYMFWASLIFMIFPILPVVTGELPAWHLLVDILFVV
                     TYLGVLITKNQRISWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTIR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(47604..48341)
                     /locus_tag="VXD01_000479"
     CDS             complement(47604..48341)
                     /locus_tag="VXD01_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0600921.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(48343..49227)
                     /locus_tag="VXD01_000480"
     CDS             complement(48343..49227)
                     /locus_tag="VXD01_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0600922.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(49214..49408)
                     /locus_tag="VXD01_000481"
     CDS             complement(49214..49408)
                     /locus_tag="VXD01_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600923.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(49405..49611)
                     /locus_tag="VXD01_000482"
     CDS             complement(49405..49611)
                     /locus_tag="VXD01_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600924.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        14344 a        11358 c         9538 g        14591 t
ORIGIN      
        1 aaacaaggaa aaagaaaggg gtttcacgaa tgaagaaaaa tcgtggaatt caaaaattag
       61 ctatattagt attactaggt gtttttatgt ttagtaacac aattccttac caacagttat
      121 tcagaagaat agacaattgg agattcgagt gcaatcacaa aagaagtcca atggtcttga
      181 tgttgggaag gctgattgat ttcgtattac tttaaaattc aactatttag agaaaggtat
      241 tctgatgaga gcttgtaaca ataccagata gatataagaa tggagatgtt tgataaaatg
      301 ctttcatagc taaccaactg ttgaaaatta tgagttacaa aatctaaagt atttaagatt
      361 ggtttataaa attaggtctc tgcctgtaga aaggaacgtg cagttagaaa ggaggaaaaa
      421 ataggatact ataattcaga ctgagatttc taattaaaat atgtagttgc atttcgctca
      481 ttttcataat atttcattta gaggagtaat aatatgttaa aatttagaaa agtagttgca
      541 tcatcccttg ccgttttggc atttagtttg gctcttcctg ttttggcagt ttctcaccgt
      601 ggtggcgagt ggacctatgg aggccatcat gatccatata attggggagc attttcgaat
      661 tattatcatg gttcacagta tcactgggcc tatgttggaa gtaatgaacg tgacaatcaa
      721 aaaacagttt atgcaggagc acatagtgcg gcctatgcgt ttgttaatac aaatttgggg
      781 gagcgaatta catttgatgc gggatggtaa agaataattg aagaagattc ttttatcaat
      841 agtttagtaa gcttgttagt ttatagaggg caggggtatt tctgccctct gttttagaat
      901 aaggaatgca ctatgaaaaa attatttata ctcatatcca acctgcttgc tagtttgttc
      961 tttgtttggg tatttaccat ttggactgat acatatgtct cccattatta ccccaacgtt
     1021 gttgtacatg attcttcccc tgaaacaact tttcagcatg ttgctacacg cttggaaaaa
     1081 ctagcagaag aaacagatag ctttattgcg attcaacacc aagatcctaa ctcagaaggt
     1141 actacagttt tttcttatac gacctttgga gacggaaagt tgcctgacgg gctacaggaa
     1201 aaaaaactag aagatgctca aagtagtagt gttgaaacaa actattttgt attcgatgga
     1261 cacctagata ttcacttgct aagggaggag ctaagtcaac ttggcttgac taatatgcac
     1321 ctgacaattc catctaaact atctacgtta atggctatct ttagtaacgg atttcagtta
     1381 atcagtctat tgattttcat cttaaccttt ggagcactga ctttaattag tcaaattagc
     1441 caattacggt cgtcgggcat tcgcctcatt tcaggagaga aacggtggtc catttttctt
     1501 agaccagttg gtgaggattt gaaagggata gctgttggtt tcagtttagc tggcgtgctc
     1561 accattctta tgcaaaaaat tctgtcgctt ccaacgcaat ccctaatgac cataggagca
     1621 ggcttgctca gttataatct catcttgttg tctatctccc tgtttttcgc tcaactcttc
     1681 gcagttggga taaaaaagat acacctgatg cagattataa aagggcaagt gcctgtcaga
     1741 ggaatcatta gtttgatttt aatcggtcaa ctattagcga ttattattgt aacactggga
     1801 atagggagta gcttaaagta ttcccaagcc tggcaacagc atcggattgg acaagaggct
     1861 tggagccagg aaaggcaact gattacccta tcaatcagcc gtgaaggaac gagtcctggt
     1921 tttgatgaac aagctcaaag gaaactcaga acttggtatc aattgatgga tctggctgtt
     1981 tcagaacaaa aggctttctt atctagacac cagttaattg accgtacttt gcaaaatggc
     2041 atggcttcct ccaaaaactt tataacctct acagaatggc acgattacag cccgaatggc
     2101 aatgtcctta tcgtcacacc gcaatacttg gagcgtcaaa acattcctgt agatacaact
     2161 attgagcaaa agatgaatca ccttgatgta ggggagtttg tcttattgct gcctgaacac
     2221 ctccgttcag aggaagatca ttataaatct gtttttgaag acgacttaac cagtcgcatg
     2281 tctagtcaag atgaacgaca gcaaatgact gctacggtag gttatttaga atcaggtcag
     2341 gatcgttttg tgtataatac gacccctatt tcttaccagc agtttttgaa agatccaatc
     2401 atcattgtta taacacccca atcaactggt ccacagtcca ttttgttttg gatagacgca
     2461 gtacagaact acgttctctt taatcaattg tctgatgccc aggagcttat ccagagacaa
     2521 ggcattgaaa attgggtctc agaaatgcaa acaggttacc acaactacat cacattattg
     2581 gataatatcc agagggaacg ttgggtaatg ctagcaggag ctgtgcttgg gattgcaact
     2641 tcaatcttgc tgtttaacac tatgaatagg ctctactttg aagaatttag acgtgccatt
     2701 tttatcaaac gcattgcagg tctcaggttc ttagaaatcc atcgcactta tctctttgct
     2761 caactgggtg tgtttttact gggatttgtt gctagtgtat ttcttcaggt agaaatagga
     2821 gttgctttct tagtcttgtt actctttact ggtctatctc ttttacagtt acatgtccaa
     2881 atgcagaaag aaaacaagat gtccatgctt gttttgaagg gaggttaata tgattgaact
     2941 taaacaggtg agtaaatctt ttggagaacg agagttattt tcgaatcttt caatgacatt
     3001 tgaggctgga aaagtctatg ccttaattgg ttcaagtggt agcggaaaaa caaccttgat
     3061 gaacatgatt gggaaattag aaccttatga tgggacgatt ttttaccgag gtaaagactt
     3121 ggccaattat aaatcgagtg attttttccg tcacgaattg ggctacctct tccagaactt
     3181 tggcttaatt gaaaaccaaa gtattgaaga aaaccttaag ctaggtctca ttggtcaaaa
     3241 gttgagtcgg tcggaacagc ggttgaggca gaagcaggct ttagaacagg tcggcctggc
     3301 ttatcttgac ctagataagc gcatctttga gttatcgggc ggagaatcgc aacgagttgc
     3361 cttggcaaaa attatcttaa agaatccacc ctttattctg gcagatgagc caacagcttc
     3421 aatagaccca gcaacctctc agttgattat ggagattttg ctatctcttc gagatgataa
     3481 taggctaatc attatcgcaa cacataatcc ggcaatttgg gagatggctg atgaagtgtt
     3541 cacgatggat catctgaaat aaaaatcctt gtttttaatt gcacgatgag ttactgaaat
     3601 attatcatga atcaagaatt ggagttaatt tagaattgta ctttattaat attgaggtaa
     3661 ctttttcttg ataaaggagg aaatagtgga gaggaagtta gaatgaaaaa attcgacaat
     3721 tatattattg agaagccttg cgattctaat tcagataaac tgcaaaaaat cttaataatt
     3781 gaaaatttgg tagatgatat tttgcaattt cctctcagaa tcaataatag tgtaggagag
     3841 attttcctcc tacaaccgtt tcaaaagaaa actatcttta ttccatgtta ttttgaggaa
     3901 gatattgtga aagtcaaaga tgatgataaa gttgagtgga atttgttaga atttcaaaaa
     3961 tttagagcat ttttggctta gtaatctgtg ttgaaggctc aaaacctatg gtaaaaaagt
     4021 cgctttgaaa acgtattgcc tccaaagatt tagttaaata atgatttaac acaaaaagaa
     4081 attattgaag ttctggaaag atgttgtttc agtattgaga aaaggtggga aaaacttgcg
     4141 attttcacag agaaaggaag aaaaagtata gaaatatagt caattgaaac aagaacagga
     4201 caaaagaacc ttttgtgcca tatttttctc ctttcgcttt acaattggct tgaacacctt
     4261 tattgtatcg cgtttggagt ttttttggta taaccttcga cgcgcacccg catagcgggt
     4321 gtttttttgt ctcgcaccta acggagcgag acgaactaat agtcacttaa tcaaaaaaac
     4381 gcaccatatc aaaaactaaa aagtttgata tcatgcgtca tgtcttaaac taattgacta
     4441 tactttctat tcaaatgagc ttttaaccaa ttgattgagc caatccactc ttaaaaccaa
     4501 agagcaattt ctcgcttagc tgactcttct gaatctgaac catgtacaac attttggata
     4561 acctcatttt ctccagcagc ttttgcaaag tcacctcgaa tagtgcctgg taaagcttct
     4621 tctggacgag ttgcacccat catggtccgc caagtttcga ttactttggg accagaaatg
     4681 acacccacaa gaactggacc tgaagtcatg aattcacgaa tcggtaggta aaaactctga
     4741 ccaaccaagt cctgatagtg ctggtcaatc aactcttctg aaacctgtga acgaaactcc
     4801 aatttttcga ttgtaaatcc acgttgttcg atgcgcttta acacttcacc cactagccct
     4861 ctttttacac catctggttt gatgataaag aatgtttgtt ccatacccgt ctcctttgtc
     4921 agcttctttc ttttatttta ccacatttcg tggaaaaatg gagaaagttt tcagaagaga
     4981 gaatgagaga acccgagggt tctctcattc tctcttattc tactgtttct tccacagttt
     5041 caacggcagt atccacaact acttctgttg tttcttcatt tccttcttcc tctactgtag
     5101 gattaaggta ttcttcttcg ttgacagcat gtggttcaag gttacggtaa cgggccatac
     5161 cagtaccagc tgggatgatc ttaccgatga taacattttc tttaagtcca aggagatggt
     5221 ctttcttacc acggatagct gcgtcagtaa ggacacgagt tgtttcttgg aaggaagctg
     5281 ctgacaagaa actgtttgtt tcaagtgagg ctttggtaat tcccataagg actgggcgac
     5341 ctgtcgctgg aactccacct gcgataagga catctttgtt ggcatctgta aagtcattga
     5401 tatccatgag ggtacccatg agaagatctg tatcacctgg atccatgaca cggactttac
     5461 ggatcatttg acgaaccatt acctcgatgt gtttgtcacc gatttctacc ccttggctac
     5521 ggtaaacttt ttgtacttca ccgagaaggt acgtttcaac tgacaagaca tcacgaactg
     5581 caaggagacg ttttggttgg atagaacctt ctgtcagagc agcaccacgc gctacttggc
     5641 ccccaacttc gacacgcata cgagctgtaa atggaacgac atattcacct tcgccagttt
     5701 cacccttaac aaagactttc ttggtacgag ttgatgcatc ttcttcgata gcagtaactt
     5761 gtcctttaac ctctgtgata accgcttccc ctttaggatt acgggcttca aagatttctt
     5821 ggacacgagg aagaccctga gtgatatcgg tatttgaggc aaccccacct gtgtggaagg
     5881 tacgcattgt aagctgtgta ccaggttccc cgatagattg ggcagcaatt gtaccaactg
     5941 cttcaccaac ttcaaccgca tcaccagtcg ccaagttgat accgtaacag tgacggcaga
     6001 caccgtgacg agtgttacat gtaaatacag aacggatagt cacttcttcc acaccagcat
     6061 tgacaatttc acgcgccttg tcttctgtaa tcaattcatt tggaccaata atcactgcac
     6121 cagtttctgg atgtttaaca gttttcttag tgtaacgacc gttgagacgc tcttcgagag
     6181 actcgatcat ctcttttcct tctgcgatag aacggatcaa gagaccacgg tcagttccac
     6241 agtcgtcctc acggatgata acgtcttggg caacgtcgac caaacgacga gtcaagtaac
     6301 ctgagtcggc tgtcttaagg gccgtatcgg tcataccttt acgagcaccg tgagttgaga
     6361 agaacatttc caataccgac aaaccttcgc ggaagtttga aaggattggc aattccatga
     6421 tacgtccatt cggagcagcc atcagaccac gcataccggc aagctgtgag aagtttgaga
     6481 tgttaccacg ggctccagag tccatcatca taacgattgg gttcttagga tcttggttag
     6541 caatcaagcg tttctcaagt ttttcacggg cagcacgcca ttcagctgta acagcattgt
     6601 aacgctcgtc gtctgtgatc ataccacgac ggaattgttt ggtgatttgt tcgacacgtt
     6661 tgtgtgattc ttcaatgatt tcagtcttgt catcaacgac tgggatatcg gcaataccca
     6721 ctgtcaatcc tgcaagagtt gagtggtggt aaccgaggtt cttcatgcgg tcaagtaggg
     6781 cagaagtttc tgtcgtacgg aaacgtttga agatttcagc gatgatattt ccaaggtttt
     6841 tcttcttgaa tggagggttg agctcaagat tgctgatagc ttccttgata tctccaccaa
     6901 gtggcaagaa gtatttagct ggaacacctt ctgtcaagtt ggcattgttt ggttcttgca
     6961 agtatggtag cccctctggc atgatatcgt tgaagagaat tttaccaact gttgtaagca
     7021 agaccttatg tctttgctct tctgtccaag gcttgttgag gctgtctgtt gcgataccaa
     7081 cacgtgagtg gaggtgaaca taaccattgc ggtaagccat aaccgcttcg tcacggtctt
     7141 tgaagaccat tccttcacct tcgcgaccag cttcttccat ggtcaagtag tagttaccca
     7201 aaaccatgtc ctgagatgga gtaactaccg gtttcccatc tttcgggttc aagatgtgct
     7261 cagcagctag catgaggata cgagcttctg cttgtgcttc ttctgaaagt ggtacgtgga
     7321 tggccatttg gtccccgtca aagtcagcat tgtaggcttc acagacaagt gggtgcaagc
     7381 gaagagcctt accatcaatt aagactggct cgaaggcttg gatacccaaa cggtgaaggg
     7441 tcggtgcgcg gttcaaaagc actgggtgtt ctttaatcac ttcttcaagg atatcccaga
     7501 tacgctcatc tccgcgttcc accaagcgtt tagctgcttt gacgttttgc acgatatcac
     7561 gggcaacgat ttcacgcata acaaatggtt taaagagttc aatcgccatt tcacgtggca
     7621 caccacattg gtacatctta agagttggac caacggcgat aacggaacgt cctgagaagt
     7681 caacacgttt accgagcaag ttttgacgga agcgtccttg tttaccttta agcatgtggc
     7741 tcaatgattt caatggacgg ctacctggtc ctgtgattgg acgaccacga cgaccattgt
     7801 caatcaaagc gtcaactgct tcttgaagca tacgcttctc attttgaacg atgatacctg
     7861 gtgcatttaa ctcaagcaaa cgagccaaac ggttgttacg gttgataaca cggcggtaaa
     7921 ggtcattcaa gtcagatgag gcaaaacggc caccatccaa ctgcaacatt ggacgaagat
     7981 ctggtgggat aaccggaagg atgttaagaa tcatccattc aggtttgttt ccagacttgt
     8041 aaaaggcatc caaaacatcc aaacgacgga tggctttgac acgtttttgt ccagtagctg
     8101 ttttcaattc ttctttgagt tcagcaattt ctttttcaag atctacttgc ttcaaaaggt
     8161 cttggatggc ttccgcaccc atcttggcaa caaatgaacc ataaccatat tcacgcaagc
     8221 gctctcggta ttcgcgctct gtcatgatag acttgtgctc aagtggtgta tccttaggat
     8281 caatcaccac ataagccgca aagtagataa cttcctcgag ggcacgaggg ctcatatcaa
     8341 gggtcaagcc catacggctt ggaatcccct tgaagtacca gatgtgagat acaggagctt
     8401 tcaattcgat atgtcccata cgctcacgac gaactttcgt acgcgttact tcaaccccac
     8461 agcggtcaca aacaattcct ctgtaacgaa tgcgtttgta cttaccacaa gcacattccc
     8521 agtcttttgt aggaccaaag atcacttcat caaagagtcc ttcacgttct ggtttcaagg
     8581 tacggtaatt gattgtttca ggttttttga cttctccata agaccatgaa cggactttac
     8641 ttggagaagc tagggtgatt tgcatacttt taaaacgatt tacatcaacc actatttctt
     8701 ccctttctat tctaagtgaa ctgcttattc ttgttcagca gcttcttctg ttgcttccgc
     8761 ttttgttgct ttctcagctt cttcagcttc aaaggctgct ttagcctctt gggctgcttt
     8821 ttcgcgggct ttttcaaggt catctacgtg gatgacatct tcgtccattc cttcatccaa
     8881 gtcgcgaagt tccacttctt ggtcatcttc gtctaggaca cgcatgtcaa gaccaagaga
     8941 ttgcaattct ttgacaagaa ctcggaagga ttctggaaca cctggttttg gaattggttt
     9001 gccttttgta atagcttcat aggctttcaa acgtccgttg atatcgtcag acttgtaagt
     9061 caagatttct tgaaggacat ttgacgcacc gtaggcttca agagcccaaa cctccatctc
     9121 accgaaacgt tgtccaccaa actgagcttt acctccgagt ggttgttggg taacagttga
     9181 gtaaggtccg actgaacgcg cgtgcaattt atcgtcaacc atgtggtgga gtttgatcat
     9241 gtacatgact ccaacagaaa cacggttatc aaatggttca ccagtacgtc catcgtaaag
     9301 gatcgttttg gcatcgctat ccatacctgc ttctttaaca gttgaccaaa gatcttcaga
     9361 acttgctcca tcaaagactg gtgtcgcaat gtgaatacca agagtacgag ctgccatacc
     9421 aaggtgaagc tccataacct gaccgatatt catacgtgat ggcaccccaa gtgggttcaa
     9481 catgatgtcg actggagttc cgtctggaag gtaaggcatg tcttctacag gaacgatacg
     9541 agagacaacc cctttgtttc cgtgacgtcc ggccatttta tctccgacct taatcttacg
     9601 tttttgagcg atgtaaacac gaaccaacat gttaacacct gattgcaact catctccatt
     9661 tacacgtgta aagatcttaa catcacgaac gacaccatcg gcaccgtgtg gtacacgaag
     9721 agaagtatca cgcacttcac gagacttgtc tccaaagata gcgtgcaaga gacgttcttc
     9781 agctgaaaga tctttctcac ccttaggtgt tactttacct acaagaatat caccttcttt
     9841 aacctcagca ccaatacgga taatccccat ttcgtcaagg tctttgaggg catcttcacc
     9901 aacgtttgga atttcgcgag tgatttcttc aggcccaagc tttgtatcgc gcgtttctga
     9961 ttcgtattct tcaaggtgaa cagatgtgta gacatcgtcc ttcaccaagc gttcgctcat
    10021 gataacggca tcctcgaagt tgtaaccttc ccaagtcatg taggcaacga ttgggttttg
    10081 tccaagcgcc atttctccat tttccataga aggtccgtca gcgatgaaat cgcctttttc
    10141 aacgacatca ccaactttta cgagagtgcg ttggttgtaa gcagtacctg agtttgaacg
    10201 acggaatttt tggatgtggt aaacatccaa tgaaccatct tcacgacgaa cttctacctt
    10261 gtcagcatct gcgtaagtaa ctttaccatc atactgagca atcacagccg caccagaatc
    10321 gtgggctgct tggtattcca taccagtacc aacgtaaggt gcctgaggat taatcaatgg
    10381 cacagcctga cgttgcatat tggctcccat gagggcacgg ttggagtcat cgttttccaa
    10441 gaaaggaata catgctgtcg caacggcaac tacctgtttt ggtgaaacgt ccatgtagtc
    10501 aacaatatta gctggatact cttggttgac cccttggtga cgtcccatga caatcttctc
    10561 agcaaaggtt ccatcttcat tcagacgaga gttagcctga gctacagtat attcatcttc
    10621 ttcatcagct gtcaaccaaa caatttcgtt cgtgacaaca cctgtttcac ggtcaacctt
    10681 acggtatggt gtttgaacaa aaccatattt gttcaagtgt ccgtaagatg acaagttatt
    10741 gatcaaaccg atgttaggtc cttcaggtgt ctcgattgga cacatacgac catagtgagt
    10801 gtagtgcacg tcacgtactt catatccggc acggtcacga gtcaaaccac caggtcctaa
    10861 ggctgacaaa cggcgtttgt gagacaactc agaaagcggg ttgtgttggt ccatgaactg
    10921 tgacaactgt gatgaaccaa agaattcttt aactgcagct gttacaggac ggatattgat
    10981 aatttgttgt ggtgtcaaga cttcattgtc ctgaacagac atacgttcac ggacattacg
    11041 ttccatacga gaaagtccca aacgtacttg gttggcaagc aattcaccaa ccgcacggat
    11101 acgacgattt ccaaggtggt cgatatcatc tacacggcca agtccttcag ccaagttgag
    11161 gaagtagctc atctcggcaa ggatatctgc aggagtcacc gtacgaacct tgtcatctgg
    11221 gttagcatta ccaatgatcg ttacgacgcg atctggatca gttggagcaa caaccttgaa
    11281 tttttgaaga acaacaggct cagtcacaac ggctgcatcg tttgggatgt agacaatctt
    11341 gttcaagtcg ccatccaaat ggctttcaat gctttcaatc acgctacgag tcataatcgt
    11401 accagcttct accaagattt ctccagtttc agggtctacc aatggctctg caatggtttg
    11461 gttgagcaaa cgtgttttaa cattgagttt tttattgatt ttgtaacgac caactgctgc
    11521 caagtcatag cgacgtgggt caaagaagcg agccacaagc aagctacgtg agctttcagc
    11581 tgtcttaggc tcacctggac gaaggcgttc gtaaatttct ttcaaggctt cgtctgtacg
    11641 agagtccatt ggattcttgt ggatatcttt ttcaacagtg ttgcgaacca attcgctgtc
    11701 accaaagata tcaaagattt catcatcacc tgagaaacca agagcacgaa ccaaggttgt
    11761 aaatggaatc ttacgagtac ggtcgatacg agtgtaggtg atatcttttg agtcgctttc
    11821 aagttccaac caagctccac ggttagggat aacagttgaa ccatagccca ccttaccatt
    11881 tttgtctact ttgtcgttaa agtaaacacc tggtgagcgg accaactgag aaacgataat
    11941 acgttcacca ccattgatga tgaaagtacc catttctgtc atgattggga aatcaccaaa
    12001 gaaaacttct tgggtcttga tttcgcctgt ttctttattg atcaaacgga aggttacaaa
    12061 aattggtgct gagtagctag catcgtggat acgagcttct tctagcgtgt attttggttc
    12121 cttgatttca tatccaacaa attccaactc cattgtgtct gtgaagtttg aaattggcaa
    12181 tacatcttca aacacttcct taagaccgtg gtctaggaaa gctttgaatg agtcagtttg
    12241 aatttcaatc aaatttggta agtcaagaac ttctttgatt cttgaaaaac tacgacgggt
    12301 acgatgtttc ccgtattgaa cgtcatgtcc tgccaagatg attctccttt gtaaataagt
    12361 tccaagcctt gtcaatcagg cttttctaat cgccatatgg ttgtaaaccc cttatcaccg
    12421 tgtcctcttg acgaattttc agaatcttta agcctctgtt acaaatgctc aaaatcttga
    12481 aaaaaagcac aaaaagagca gctaaatctg actttttcag aagatttaac tgctgtgagc
    12541 cttgtctgga caatatttca gacaaaacct acgacaaatg attacccata ttatacccta
    12601 tttagctaga tttttcaagg ggtttcagta ggtttttggt aaattttttc ccatagaaaa
    12661 cttggcatca cattcgaatc acgctatggt acaaaaaact gaaaaaacta ttgactgaaa
    12721 atcattttca aggtataata ataaacgtta aggcggtata gccaagtggt aaggcacggc
    12781 tctgcaaaag cttgatcgtc ggttcaaatc cgtctaccgc cttctataac ttgatttatc
    12841 aggtttcaaa tgaacagaaa gcccaatttg aagggctttt cttattttcc ctcgaataaa
    12901 tacgtataac tttaaaaact tttggagcga gtttgtggca gagttctttc catggcataa
    12961 ttcccttttg aaatcaattg aaaaaagctt cgtcacgcct ggtgacaaaa gcctctagtt
    13021 tattctgttt cttcttctat ttcgacttct gtgatttgga tttttacctt ggtaacacgt
    13081 ccattcttca ctttatcatt ggttaagata aactgtttgt tttggctgat caattcatag
    13141 ctgagtttct cagtcgttgg aatggttccc actcctgtca aataataacc agcgatagta
    13201 tcaacgtcat cactttccag ttcaacatta aagtaattat tgaaatcatt gagggtcata
    13261 gttccttgaa caatgtaggt atcctcgcca atctgataaa catctattgc tgctttgtcc
    13321 gtttcatcat caatttcacc aacaatttcc tctaagaggt cttccaaagt caccaaacca
    13381 gccataccac cgtattcatc cagcaagatt gccatttgtc tttgggtatt tcgcagttct
    13441 tttagcaagt catccacaaa aatagtttca ggtacaaaaa gtggatcttg taaaattctc
    13501 ttccaaacaa tattgtcaaa accgtccaca aagcctgcct taaggagact cttggtgtga
    13561 atgattccaa ttacattgtc cttatcccca tcataaaccg ggatacgaga ataattttgt
    13621 tttaaaatac tttggataat ggcttgacta tcatcctgaa tatccaccat aaaggcatcc
    13681 gttcgaggaa ccataacctc tcgtgccatc agttcatcga gcgaaaagac accttgtagc
    13741 atctcaatct catcagcatc caatgtttct tcactatttg tcagcatata ggcaatttca
    13801 tcacgggtca tcttttcatc cgcatcatcg aatgacatag gagtcaaatg gctcaagaaa
    13861 ttggtcgaag cagctaaaag ccaaacaaaa ggactgacta gttttccgat cccaatgata
    13921 accggcgctg tacgaattgc caaggcatcc tttagattaa gagcgattct cttaggatat
    13981 aattccccaa aaacgatgga aatataggtc aaaaatgcca aggatagaaa agttgccacg
    14041 gcttgtgctg tttcgccatt cccaagccaa gaggcaatca cacgtcctag agtatcagtt
    14101 aaactcgccc ctgataagat tgtaatcagg gtgattccta cctgaatggt tgataaaaag
    14161 tggttaggat tttctagtac cttcagcagg cggatgtagc gtctgtctcc ttcttccgcc
    14221 ttttgttcaa ctcgggcacg attaagagaa accatggcca tttctgtggc tgagaaaaag
    14281 gcatttaata ccgtcaagat aaacaataaa acaaattgta gcaacaaatt ctgactactt
    14341 gggtcttcca tagttcttct cctaaaatag tatcttatcc tttattatat cacaaaattt
    14401 aatccaatac atattatttt tttcttagcg taacttccat ctctctccca aaactggaag
    14461 ttagtctaag acggatttcc actgatttca cgcgtttttc tcatactaaa agctaggttg
    14521 tgggaaactg gaagttagtt ttagaagttg ctattttttc ttagtacctg ttctagccct
    14581 gcttaaacta gtaaaaagaa ctcctacatc cataagtgac ataggagttt aggcttatct
    14641 tttactgagt tacagttact tctccagttc ggtaatccag ttgaagtccc ttttgaacat
    14701 tgggaactag aacattgaat tccaattctc catccgaaga cttggcttca atctgtgaag
    14761 ctgagggaac taaatcctcg tttgaagcgt agtaaagggt tacacggtaa cggacacgct
    14821 tgttttggtc caaggcttta cgcaccttgc tttcatagta gttttgacca gtcgaatact
    14881 cggcttgtgc ctgatttgcc caggctgtct gaacagcaat gtttttagga ttgcttgttg
    14941 aggcatcaaa accatccaaa ccaccgatta aggcatagcc taacaaatga cctctatcga
    15001 ctgcatgggt ataagagccc tttagattct tgacctgatg ccaacctgga ggagtccaag
    15061 aagttgaacc attcccagtt tctttacgat tcttgtactg acgagtggca ttagacaaga
    15121 gggcattagc tacggttgga acagtttcct tgcccactgt ctttgtttta ttgtcagcgt
    15181 agggcttact tgaaaccttg gcatctagat ttgttttatt accattgacg ataaaagcac
    15241 ctgagccatt ccactccaga ctccccttta tttgactctt gactgcgtct gttaagacac
    15301 tctctgccaa tgcttgacta ggagcttcag gcgcttgttt tttctgacta agattggttt
    15361 tgggactatt aggtgccgac tgcatctgct tgatataata gctccctgta gacaaaagca
    15421 ataacactag cagtccgatt agtgtctgtc ttgttttttt gttcatattt ctccttatct
    15481 ttagaaaaag gctggttctc cagcctaatt tcctgtaaat ttatgaatca attcctgcca
    15541 ttttgctgga gacaggatag cccatggatc ttgacccttg cccaagattc cataacctac
    15601 cattagaccg attcctagag ccagagtacc taaaatcagt actatgatga ctaaaagtaa
    15661 acgcttgact acgtagcttg atttcttatt catcttcatc acttgcctca atccgctgaa
    15721 tcttagcacc tagctgcgcc aacttctcat ggaaaccgta gtaacctcta tccaagtgaa
    15781 ccaatttacc gaccacagtt tctccctgtg ctaccaaacc tgtcaaaatc aaagctgcac
    15841 tggcacgaag gtcagttgaa agaacttctg ctccctgcaa aggctgtcca ccaacaatac
    15901 gagctgtatc acggataatc tcagaatgca agcccatgcg gcgcatctct tctaggtgtt
    15961 ggaaacgatt ttcaaaaact gtctccacca tggttgattc gccttttgca actgtcatca
    16021 aggctgtaaa ttgagcctgc atatctgttg gaaatcctgg gtggggcaag gttttcacat
    16081 gaacagcttt tagattttcc agttgagaac gaacacgaat tccttcgtct tcttcaatta
    16141 cttcaacacc catttcaagt aacttggcaa tcaagggacg gttgtgctcc cagacagcgt
    16201 ctcgaatcaa gacatcacca ccagtcatgg cagcagctac cataaaggtt cctgcttcga
    16261 tacggtcctg gactacattg tgagtcgtac catgaagttt ctcaacacca gtaatggtta
    16321 tagtctctgt accagcacct ttgaccttgg ctcccatttc attaaggaga atggctaagt
    16381 caacaatctc aggctcacgc gcagcattct caatcactgt caccccatca gccagagtcg
    16441 ctgccatcat caagttctgc gttgcaccaa cacttggaaa gtccatatag atatgagcac
    16501 catgcaagcg ttctgccttg gcttcgatgt aaccagctgt ctgactaatc ttaaccccca
    16561 tagcttccag acctttcaaa tgaagatcaa taggacggct accaatcgta caaccacctg
    16621 gcatggatac cttggcatga cccacacggg caaggattgg ccctaataca acgatggagg
    16681 cgcgcatctt actgacatac ttgtaagggg cttcctcagt gatgtcgcca gtagcatcca
    16741 ccttgacaag atgagcttcc tcatcaaagt caaccttggc attcaaacca ccaactacct
    16801 gattcataat aaagacatcc gacaaaatcg gaacattctg caagacggtc tttccttcac
    16861 ttgctagaat agtcgctgcc aacaagggta agactgcatt ttttgctccc tcgatcgtca
    16921 cgcttcctac cagacgatta tcgccacctt gaaccacaat tttatccata ctcgtttcct
    16981 ttactcttga ttttataata atcctctaag cgcttcttgc cacaaatgat acaggctaat
    17041 aaagaaagaa ctcaggatgt agcctatgac aatgctaaaa aaggctacta atacacgaac
    17101 ttttcttgta ttctcagctg tcacttttaa aaccttttcc catctaacaa gatcctttaa
    17161 aaggtaaaaa ctcacataaa taaagagcat atgactactt agagtgaata ataattgaac
    17221 catttgacta ttataccatc ttctctgttt gtgcgctagt ttggaaactt cactcaaaaa
    17281 ttagggattg tttttcaagt aatcaatcgc atcttgtagg gttttaacgg gcacgatttt
    17341 catatccgtc ttgattgttt tagccgcttc tagggctgtt tggtagttgt ttttcgcgtc
    17401 cggatgcgcc ttttgttctt cttcgctaac agggttatca ggagcaaaga aaatagcagc
    17461 acctgcccta gccgaagcta caaccttctt atcaatacct ccaatgtctc ccacattacc
    17521 atcgcggtca atggtacctg taccggcaac aatacgacca ttacgaagat ctgggtgagc
    17581 tatttgagta tagatagcta gactaaacat gagaccagca cttgggccgc caataccagc
    17641 tgttgaaaag ctaattggga cattgctgat tacctctgta cgatcaatca agccgattcc
    17701 aatcccattt tttccatttt ccaaggtgat aatctttcct tctgcagact tggtttgccc
    17761 atcctcttca taggtgacct tgacggagtc ccctaatttt tgagaactga cgtaatcaat
    17821 caagtctttg gaactatcaa aggtctgatc attgactgct gtgactgtat cagagatatt
    17881 gagaatccct ttaaaggttg aattatccgt cacattcaaa acataaactc caaagtactt
    17941 gagttcgata tccttaccag ctgtttttag tccttgatac ttggccatat tttgcgatgt
    18001 ttgcatgtag aattgattga ttcgcataaa ttcaacatcg gaagaaccac ctgtagtctc
    18061 ctgagcacta cgaatatctg taaaaggtgt caaccaagca taaatcatat gagctaaagt
    18121 agcatgttga acaccaaccg taacgaattg ataggcacca gcttccttat cttctgtgtc
    18181 atttacttta aggacttggc gaatatcttc cgaaccacct ggaacctcta tatagtaggg
    18241 caaaggcacc acaaatgcca agaaggtcac aatcaaggcc gcaatgacat acaagggcca
    18301 tctaatcttt tttttcattt cttatttcct ccaaaatact ctcgggaaca tggcaggcaa
    18361 tatcctgacc aaacttcaaa agctctcgaa cacctgatga actgatatag agatgttcag
    18421 gccggctatg taaataaata gtctctatat cagaagacag ctgatgattg tagtaatcaa
    18481 aactagcttc atattgcaaa tccgccgcat tcctcaaccc ccgtactagg aaagtagccc
    18541 ccagtctttt tgcaacatcg accaccaatt tatcatgaga agccacgact tcaacatttt
    18601 ccaaatgtcc caaagccttt tctagccccc gtttacgatt ttcaagaggg agaaatcctt
    18661 gtttgtgggg attaaaaaaa atacccacat aaagcttatc aaaaagtctg ctcgcccgtt
    18721 caatgatatc cagatgccca tttgtcatcg gatcaaatga gcctgtgaat aagccaatct
    18781 tatctgacat agactgtcac cttactaatt ccataaatct tttccttcca gatacccaga
    18841 caggcaattt cttctggaag ttcaacggct ttatccgtct cgcacacaac cataacatct
    18901 tcagaaaaaa gctctctctc agccattttt tcaatatctg ctacgatttg ttccttggca
    18961 tagggagggt ctaagaaaac gaggtcaaat tccccagata cctgttccaa tgccctttct
    19021 gcatccattt tgaggagttg aaattttcca acttccttgg tcatctggat attttcagcc
    19081 acgatggtct gagccttacg gtctcgctcc accaaaacag cactggacat gccacgcgat
    19141 actgcttcga tagataaacc accactacct gcataaaggt ccaagactcg tcccccttca
    19201 aagtagggac caatcatgtt aaaaatggct cccctaacct tatccgaagt aggtcttgtt
    19261 gtcttgcctt ctagtgtctt aaggggacgt cccccataga ttcctgatat gattttcata
    19321 ctgtttatta taccaaatta tagacaaaaa gagaaagaaa accgaacctt gcggttcgat
    19381 tctctacaaa atattttcgt aagtatcgcg gacttcttga ggccaaacac ttgtttgcac
    19441 ttctccgatg tgtctcttgc gaagtaggaa catggccata cgagattgtc caattcctcc
    19501 accgattgtc aatgggaata ggccattcaa caaagacttg tgccattcca attccaagcg
    19561 gtcttcatca cctgtaattt ccacctgacg tctaagagtt tcttcatcta cacgaattcc
    19621 catagaagac aactcaaagg ctccacctaa agactcattc cagacaagaa tatcaccatt
    19681 tagacccttg tagccattct cagactcgct tgtccagtca tcatagtctg gtgcacgtcc
    19741 atcgtgcggt ttaccatctg gcaactcgcc accgatacca atcaaaaaga cggctccaaa
    19801 ttctttacaa atcgcatttt cacgttcttt cggtgtcaag tctgggtagc gttctaccaa
    19861 ttcttctgta tggataaagg tgatttgttt tggcaagata gactcgatgt catagcgggc
    19921 ttcaacagct agctcagtca ggcgaatagc cttataaatc ttctcaactg tttcttttag
    19981 ataaacgatg ttacgcttac catttgggat aaccttctcc cagtcccact ggtcaacata
    20041 aacagagtgg gttgcatcca aggaatcctc atctggacga agggctttca tgtggacaaa
    20101 gagaccctct ccttcaccaa agccaaaacg agccaaggtg tggcgtttcc atttagcaag
    20161 tgagtgcacc acttcataag tagcatcagg gatttggaga accttgaccg atactggatt
    20221 ttccacacca gacaggttgt cctgcattcc gtcaccgacc ttactcaaga taggaccttg
    20281 aacttcgaca acttctagct tatctttcaa atactgggta aaagtgtttt tgacaaagga
    20341 aatttcttct tgttgatgga taaaactttt cttcatagac aactcctcaa aaatttaata
    20401 aacgtattat acacctattt ccaagaaaag aaaagagaaa atttaaaaaa aaatcagtgt
    20461 cactcaaaac actgatttca tagacctttt agtcattgcg accaaagata cgtagaatac
    20521 ttaggaaaag attgataaaa tcaagataga tgctgagagc cattgacacc acccagcctg
    20581 tcgctacacg accttgtgat tgttcatagg cgaggcgaat cttttggtta tcccaagcaa
    20641 tcaaccctga aaaaaccaaa accatggcta cgctaatcat ataatcaaag aagccactag
    20701 ccaagaaaat attgactacc atagcaatca gtaaaccaat gagagctgcc atcattgctc
    20761 gaccaatccc actcaagtct ttcttggtaa agataccaac tgccgccatg acaaagaaga
    20821 gaagggcgct cgatacaaag gcagataaaa ctgtacccgg agtatagaaa gccaccacaa
    20881 aactaagggt aaagccgttt aaaacggagt aaagtaaaaa tactggaaga gcagctggac
    20941 tatttcttga agccatacta ctagcaacga aaaccaaagc caactccgca aaagtagcaa
    21001 tggtcaacca gagacgcccc tgcatcaaca agtaaaccaa ctgagactga aagaccgtca
    21061 acataaggcc tgataccaaa gcagatagtc cgattcccag accaacaaag gcataaacct
    21121 tagcgtaaaa ttgattgaga cctgcacggt catgtataat agtgtgattc atccttttct
    21181 ccttttctgt gaacatcttt ccttgattat aacaaaaaaa gttaaaatta gcttaaatgg
    21241 aagattaaaa taccggctgc aactgcaaca ttcaaactct cggcctgccc cttcatgcta
    21301 atatggacca actggtctgc actttcagcc ataaggggac taattccttg accctcattt
    21361 cccataacta gtacaaaatt ttctatagaa ggcagttctc tgtaatcaac agaatcttta
    21421 gatagggttg ttgctagcac tgggatagct acctttttag tttcgtcaag aagcgcttga
    21481 ctagtcatcc ggtaaatggg cagatggaaa tgactacctt gcatggaacg tagggttttg
    21541 agactgtaga tgtctgccga cttatctgaa acaatcactc ctgtaaaacc tgctgcatcc
    21601 gcagttcgaa tgatagttcc tacattacca ggatcttgca catcttccaa aaacaagaac
    21661 ttgccctgac tcaaatcagc ttgtcctact tcttcttttt gaaccaccgc cacaattccc
    21721 tgtggagtct gagaatccgc caaatctagc aaaatatcct ctgaaatcca gacagtttgc
    21781 ggaaaagcag ctaactgatc tcgataattt tctagggcaa agattttctc aatcgtcact
    21841 ccagcttgga cagcctcttc aaacaagtgc cagccttcaa tcaaataggc agacttgcgg
    21901 tatttttttt ggtgtaattt cttggcattt tttaccacag aattggcttt tgaggttata
    21961 atagtcatag aaatattata acacaatcaa aggggtttgg tatgcaaaag gttagaatga
    22021 ttgcccaagg tagggtacag ggagtcggct ttcgttgggg tgtttacagc ttggcacttg
    22081 aaattggtgg catcacaggt cgagtatgga ataacgacga tggcacagtg gaaatcttag
    22141 cccaagcaga ctcatctgct atcatggcaa aatttatcca agaaatccga aaaggaccga
    22201 cacctttttc aaaagtaagc tacttagatg tcaaactaag caactttcct ccctactctg
    22261 actttaaaat cgcaaattag gtctccagaa ctattgtata ttttgtaaaa aaacagtaga
    22321 atagaaaggt ataattttta aagaaggaat aaaaacagtg aaatctatta aacgttttgc
    22381 attctcggct atgggagtgg ctatgttgct tgtcttgact ggctgtgtca atgtcgataa
    22441 aaccacaggt cagccaacag gatttatttg gaataccatc ggagcgccta tggctgaagc
    22501 catcaagtac ttcgctactg ataaaggtct aggctttggt gtcgctatca ttatcgtaac
    22561 cattatcgta cgcttgatta tcttaccact tggtatctac caatcatgga aggcaacgct
    22621 tcactctgaa aagatgaacg ccctcaagca cgtccttgag ccacaccaaa cgcgtctcaa
    22681 agaagcgact actcaagaag aaaaactcga agcccaacaa gctctctttg ctgctcaaaa
    22741 agagcacggt atcagcatgt ttggcggtgt aggatgtttc cctctcctcc ttcaaatgcc
    22801 tttcttctct gctatctact ttgctgccca acatactgaa ggggttgctc aagcaagcta
    22861 cctaggcatt cctctaggtt ctccaagtat gattttggtt gcctgtgctg gtgtccttta
    22921 ctatcttcaa tcgctccttt cacttcacgg agtagaagat gaaatgcaaa gagaacaaat
    22981 caagaaaatg atttacatga gcccactcat gatcgtcgtc ttctccctct tctcaccagc
    23041 tagtgtcaca ctttactggg ttgtcggtgg tttcatgatg attctccaac agtttatcgt
    23101 caactatatc gttcgtccaa aacttcgcaa aaaagtccgt gaagaactgg caaagaaccc
    23161 accaaaagca agtgctttct caacaccaag tggacgaaaa gacgttaccc ctgaacaacc
    23221 aactgctatt acaagcaaga aaaaacacaa aaatcgcaac gctggaaaac aacgttcgag
    23281 ataagaagaa aaaggcttag ctgatttgct aagtcttttt gcaagtcaaa agcccgatgt
    23341 ttccatcagg cttcttttct atccatgtac acgtttcata taatcttgat aactttcggt
    23401 atccatgagt tgtttagcgt tcttgacgcg atctgctgtt ggtggtttga ctccttcgag
    23461 ggaatatgga attccaagtt cacgccactt gaactcaccc atggtgtgat aaggtagaat
    23521 ttcaaactta tcaacatttt tgagggtctt gacgaactta ccaagttcaa tcaagtcatc
    23581 atctctgtct gtcaatcctg gaactagcac gtggcgaatc cagacaggtt ttccaatatc
    23641 tgatagatac tgggcacaag ccaagatatt tttattggtt tggctagtga caatcttgtg
    23701 ctgttcttcg ttgatttcct tgatatccaa aagaaccaag tcagtgacag ccatgagttt
    23761 gtcaaacttc tcaaggtaac gtggtttatt acggaaagga agagcacaag tgtccaaggt
    23821 acagtggatt ccttgttcct tagccttggt gaagagggca atcaggaaat caatctgcaa
    23881 gagagcttct cctccactga ctgtaatccc acccttattt ccccagaaac cacggtagcg
    23941 caaggcctct gtcaagacat catctaccgt ccgttcacgt gacttattgg actccatagc
    24001 ccaagtgtct gggttgtggc aatactggca acgcatgtga cagccctgca aaaagacaat
    24061 aaagcgaata ccgggcccat ctactgaccc aaagctttct gtcgaatgca ccattcctgt
    24121 cacttgtcca taatcaattg tttcttcaga catatcgtta ccttccttga aaacgtttta
    24181 tagttttatt atatcacgac ttgaaggaaa aacaagattt ttgcctattt tttagaaagc
    24241 aatctgtttt tcaatttcat tttcaatcta ttatcagatt attcttcaaa atcgaagcca
    24301 tataaggttg caaaatagtc ctcagggcgc tctgcacggc ggatttgacg ggctttacct
    24361 tcttcggtat agaggatttc cgcagaacgt aatttggcat tatactggta gcccattgaa
    24421 aatccgtggg cacctgtatc atgaattacc agcaaatcac cgatttctgt atgaggcagt
    24481 tcgcgattga ctgcaaattt atcattgttt tcacagagtg aaccaaccac atctaccgct
    24541 tcagctggtc catctggatg ggtcacgttg ctaatatgat ggtaagctcc gtacatagct
    24601 ggacgcatga ggttgactgc tgaggcatct acacctagat aggtacggta ggtttccttc
    24661 ttatgagtga ctcttgtgac tagagcaccg tgaggtgcca gcataaaacg acccaattcg
    24721 gtgaaaatct tgacctgacc aagacctgct gacgtaagaa cttcttcata caccttacga
    24781 actccctcac caatcaaggc gatatcgttc ggctcctggt ctggacgata attaacacca
    24841 ataccgccag aaagattgat aaagtctaac gaaatgccca acttttcctt gatttcaaca
    24901 gccagttcaa agagctgacg agccaactct ggataataga gatgggtcac ggtattggac
    24961 gctaggaagg agtgaagccc aaaagtcttg gctccttttt ccttcaagat agcaaaggct
    25021 tcaaagagct ggtccttggt catgccaaac ttagcctccc caggattgtc cataatgtct
    25081 gtccccagtt caaaaacgcc tccaggatta taacgacaag agatgatttc tggaatgcct
    25141 gctactctct ccagatgttc aatatcttca aaggcatcca agttaatggt cgcacccaat
    25201 tcacgtgcat aggcgtattc cttgtctggc gtgttgttgg aagagaacat aatctcagaa
    25261 cccagaaagt ccagtttatg gctcatcaaa agctctacat aactagagca gtccacacca
    25321 caaccttctt cttggagaat tttcaaaata gctggagttg gagtagcctt aactgcaaaa
    25381 tattccttaa agcccttgtt ccacgaaaaa gcttggttga cagctcttgc cttctcacga
    25441 atccccttct catcatacaa gtgaaaggga gtcgggaact cggcaacaat cgcttctaac
    25501 tcttctctat tgataaatgg tgttttcata agcttccttc tattctgttt gcaaagaaag
    25561 gctgggacaa tcgttccaac ctttagttct atctcttatt tatcttcgtc aaagatattg
    25621 ccaacctcaa catcgatggc ttggttcttg acatcaatat tagttacctt caagagtgac
    25681 ttgtagtcaa actgcttttc acgttcttct tgggcattgt ccgcaaagac cgctacacct
    25741 gccagttctg agtcgaactc gcgcaagaga ctaatcatac cgttgaccgt tccgccacct
    25801 ttcaagaagt catccacaat caagacacgg ctgcctgcct taagactacg ttttgaaagg
    25861 aacattttct cgatacggtc accacttgaa cctgaaacat agttgacgct aacagttgaa
    25921 ccttcggtaa ttttcaggtc acggcgcaca atgacaaaag agacattgag gacattggca
    25981 actgcatttg caagtggcac acccttagtt gctacggtca taaccgcgtc aattttttgg
    26041 tccataaagc ttttggcaat aatacgacca atatttttca agatggctgg tgtgctaagc
    26101 aaatcagaca gatagatata accacctggc aagatacggt cactttctga caacttggta
    26161 cgcaagtctt caaccatttc cttagcatcc tgactcgaaa tagacggtgt gaagatgaca
    26221 cctccgccag ccccagtcac tgtctggata tgaccgattt caatttcctc aaaggcgcgt
    26281 ttgataatga cgatatcttc tgagatggat gatttagcag actcatactt ttcagcaaaa
    26341 gtattgagac tagttagttt ataaggatta ttaatcaaat agttggaaat gacaaccatc
    26401 cgatcacttc ttcttaattt catttctatt tcctattcca tttttattca aaaaatcaaa
    26461 aagcaaacta gaaagctggt cgctggtggt tcaaaacact gttttgagat tgtcaataga
    26521 actgacaaac cctgtaatat acctgcatat atacatacga caaagcgata ctaccctagt
    26581 ttgaagagat tttcgaagag tattcatttt tgtcttttac ttattatacc atattcacat
    26641 aaaaaaacga acattcttat cctaaaaaat gctcattttt cttaaattat caatctaaat
    26701 ctggtttata gaaggaacga ttatccatag cgaagatttt attggacatc tctcctttat
    26761 ccaccaaagc cagagctgtt gacatcatca tcatgcttgc atccagattg tcaatcatat
    26821 ggataatctc tgcctccata atacgtggac ggactggact tccatattca agcaagccgt
    26881 ggtgactgag gatgacatga cgaagcaaaa cgacttcttc cttggtatca tcgatgccga
    26941 gttccataac tgtcttggta atttcgctat caatgagagc gatatgtcca agaagattac
    27001 ctcgcactgt gtactctgtc tggtctggcc ccgtcaactc gataacctta gctaagtcat
    27061 gcagcataat ccccgcatag agtaagctct tattgagctg aggataaact tcgctaatag
    27121 cgtctgccaa acgtaccatg gtcgccgtat gataagccaa gcccgtttca aaggcatggt
    27181 ggttggtctt ggcagctgga taggagtaga attccttatc atacttggtg tagagatttc
    27241 ggacaatccg ttgccagaca ggattttcaa ttttgaaaat catttgcgac atgtagtcac
    27301 gaatttcctt gacatcaact ggtgacttga ccttgaaatc ggctgggtca ttgggttcac
    27361 cagcttgagg caggcggaga gtaatttgat tgacttgagg ggtattgtta taaacttctc
    27421 ggcgtccttt catgtggaca accttacctg cggtaaaggc ctcaatgtta tgaggttggg
    27481 catcccagag cttcccatca atctcgccac tatcatcttg gaaggtaaag gctaggtagt
    27541 ttttcccagc tcgagtttgc ctcaggtcag ctgatttgat taggtaaaag ccttcaaata
    27601 gctcatcttt tttcatgtga ctaatcttca tattcttcct cattttcttg aaaatggagt
    27661 agatcaagcg caggctcgcc ttctgacaac tcaatgtgac ggagcgtccg ctcgatagct
    27721 atggtacgac ggtttaataa ttcatcaata ttgccagagg catgttggag atgtttttgt
    27781 gccttgacca gaataccacc aaacttgcca aactcggtct tgacactggc aagagtcttg
    27841 ctgatatggt cggcactctt ttggatatta agggtcttga aaccaactga tagggagtta
    27901 agaagggctg atagggtact tggtcctgca acgataatct gttcttcccg tctcaaatca
    27961 tcaaagaaga ccggattgcg gacgatttct gagtagagac cttctgtcgg aacaaacaaa
    28021 actccaaaat tggtcgtccg aggtggtgct atgtacttgt tcctaatatc cctagcaaaa
    28081 cgcttgacac ttgctaggag tgacttacga cagcgttcga tttcatcctt gtcacctact
    28141 tcataggctt cttctaagcg gtaataatct gccagtggaa acttagagtc aattggtagg
    28201 tagacgtatt cttggtcgcc ttgtccgggt aacttgatgg catactccac tcgttcacta
    28261 gagttttcaa ccgttgcgta ttctcgttcg tactgggcag gtgtcatgat gtcttcaata
    28321 atttgcccca gttgcaattc tcccagaatc cctcgcgtct tggttccaga gagaaccttg
    28381 ttaagagctc cgacatcacg ggcaactgtc tgcatttctc caagaccacg attgacagac
    28441 tccagttgtt tagaaactgt ctcaaaggaa gcctgtaagc gtgtctgcaa ggtcttttct
    28501 agtttttcct cgaccgtctg gcgcatttgt tccaaacgtt gctcatttga ttcctgcaag
    28561 gcttggagac gttggtctgt cttgtctcta gtttggagga gattatctgt catttcttga
    28621 cggacttggg tcaggccttg gtgcaattca atccgcactt cttgcaaacg gtcgctgaca
    28681 gccacttcca aatctttttg gtctaactgg ctggcttgtc tggcttggtc aaagcggtaa
    28741 tccaactggt ctgacaaatg atctgcctga tcctccaagc tcttacttaa gtgtttctcc
    28801 tgcctatcct gtctttgcca aatcagaaag agaccagcta ggttggcaat taataataga
    28861 ataagtaaac tttccatcct acctcctgtc cttgctatgc agtacgacca cataaccatc
    28921 tgggcaagtc accgacactt ccctatctat atattcgtta gaagcgtaca cttttttaaa
    28981 gaaaaaattc tcctctgtca actcatactt agctccaaga atagtcagct ggctatcccg
    29041 aactggcata aaggctagat agtcgtagtc tgaacgaggt tctagctgac tggtcccttc
    29101 tgaacaatag gcaatcaaat tttgcccatc ctcaatttct atttgacgca tatagggtgc
    29161 caacttagga ttgctaggta gaaagacatt ggccaacata tggtcaatac ggccacccaa
    29221 ggcaccgaaa atagtgacct cagcctgagg attttgttca aagatggtta agagagccaa
    29281 ttccagatct gtatcatcct tttctggtcg ggcttggaca aaatgctggg cacgtttttg
    29341 aatcacctgt cgctcttctt ccgtcacaga atcaaaatct ccgactgcta gagcaagagg
    29401 taagtcttct tccaagaccc agagcgagcc tcgatccacc ccaacaaaag catcaaaatc
    29461 tgtccgataa tgaccgcggt ttccgcctgc aaaaacggca accctagtcc agttgttttc
    29521 tgagagtttg tactcgctca ttgacttctc ccttaaagac ataggaacct gctacaaaaa
    29581 cagtcgcacc agcttctttg gcttgagcaa tagtttggtc atcaatccca ccatccactt
    29641 cgatttcaaa gttcaaacct ttttcctcac gaagagcaac caactcacga accttatcca
    29701 tggtttctgg cagaaaggct tgcccaccaa aacctggatt aaccgtcatg actaaaactt
    29761 ggtcaactag atgaaggacg tgcttgatgg cttcaactgg tgtgccagga ttgataacga
    29821 ctgaaggctt aactccgagt aaacgaattt tttggagggc gccatgaata tgaggtgttg
    29881 cttctacatg gatactgatg atgtctgcac ctgcacgcgc aaaatcttcc agatgatgct
    29941 cagggtttga caccatcaag tggcaatcga aaaccatctt actatgagga cgaaggctct
    30001 cgaccacacc tgcaccaaaa ctgatttgcg gtacaaaatg actgtccatg atatcgatat
    30061 gggcatattc tgccccagtt gcttctagac gtttgatttc acgttcaaag ttggcataat
    30121 ctgctgccag aattgacgga gcaatcttgt attgagacat aggtttctcc ttattttgga
    30181 atttttttgc tgactttttt ataggtttct ctacgatttt caatttcact aaggaattgc
    30241 aggtaattat caaaacggaa ggttgcaata acaccctctt caacagctgg tttgacggca
    30301 caagacggct catgggtatg ggtacaagta cggaacttac aatctcggct aacagtagca
    30361 atctctggga aagcctgatt gaggtcttca gcccttgata cttcatagtc cagagatgaa
    30421 aagcctggtg tatctgcgat tttacccccg ttgagattgt aaaaactaac agctcgagtg
    30481 gtatggcgac cgcgacctag actgtctgaa atttctcccg tttcaagatt gaggtctggt
    30541 acgagtttat tgagaagagt tgacttccca acacctgtct gccccataaa gaccgtaacc
    30601 ttgcctgtta acaaagacag gagttcctct ttactggtca caaagtcata gccgatgtca
    30661 ccataggtct gccggtaaaa atccagttct cccctatctt ccaacaaatc cattttggaa
    30721 atatagacaa tgggatggat gcccttgtgc tccaaaagaa ccaagaaacg atccagcaaa
    30781 ttgctgttaa aatcaggttc cttgacggac atgattacta cagcttgatc gatattgaca
    30841 ataggcggac ggaccagact gtttttccgt tcgtgaattt tgaggatata gccttctgaa
    30901 ttttcctcgg cagagaaatc tacccagtcc ccaacataag gggtatggcc ttttttacgg
    30961 aaattcccac gcgcgcgtgt ttgataaacc tggccatcac tctccacata gtagaaacct
    31021 gccaaggctt taatgatttg tccctgcatc ttagagtcct tgccctttaa gtgcgtctgc
    31081 tagaccggca aattctgcca agctgagagc ttccccacgc acacttggtg acaagcctgc
    31141 ctggtccaaa gccttggtca gcttgtcctt gacctcttca gtcttaccaa agtaacctgt
    31201 caagttattc cacaaggtct tgcggcgatg ggtaaaacta gccttggaaa ccttaaagaa
    31261 aaagttctca tcttctactg ctacggctgg ctctggacga cgcaccattt tcaagatggc
    31321 tgaatccaca tttggcgctg gcacaaagac cgtacgaggc acgataaagg caaccttggc
    31381 tgtcatgtaa tactgcacgg cgatagacaa gctaccgtaa gccttggtgt taggctgggc
    31441 tgaaatgcgg tccgctactt ctttctgcat catgaccaca aactcacaaa aaggaatgcc
    31501 actctcaatc aagtgcatga gaataggcgt cgtgatgtag taaggcaaat tagccactac
    31561 cttgattggc aggttaggat ttttaaaatt ttggatatgt tgcgccaaat caaccttgag
    31621 aatatcttcg ttaactacag tcacattatc aaaatcacgc agggtatcta ccaaaattgg
    31681 caccaaacgg tggtcaatct caaaagccat gacttgggct gcacgctcag ccagaaactc
    31741 cgtcaaggca ccaatacctg gcccgatttc gatgacattg acctggtcat caatttcagc
    31801 cgtatccaca attttttgaa ggatattggt atccgtcagg aaattttgcc cgaaggactt
    31861 tttaaaggta aaaccgtgac gctccagcac tgccttggtc acgctataat ctgcaattct
    31921 catctattct cttttctatt atctgttact actattgtaa cacattcccc ttgtattttg
    31981 ggaatgaaaa tcataccaaa aaactatctt tcctcatgaa gaaagatagt cttggaaatc
    32041 tttaaaagtg gccttaacag ttctctcgaa acatgcgttc aaaaaaatca gcttcttgat
    32101 aacttcgatt ttcaggtagg gtcaaatcca catcctcctc cacatcatcc actgtcagtt
    32161 caaccgtctg aggtaaattt ttcaaacgat aatgcttttg cctttgccct tcaatactag
    32221 caaaatcaag caaatagcca tgcactcgga tttgaaccaa aaggagatga ttggtcatat
    32281 tttccatgat gaggatatct tctaaaccac ctctggcact aggataatca gataccctgc
    32341 gaatacggat tttttcacac atgagcaagt ttcctcatat caatgatttc atcagcctta
    32401 ttccagacta ggggattatg ggtcgcaatg atgataattc gattttcatc tttcaaatcc
    32461 accaagagat tcataacctc ctctgaattt tcaggatcaa gagctgctgt tggttcatct
    32521 gccaaaatca agggtggatt tttcaaaata gtcttagcaa gggcaactcg ttgggcctct
    32581 cccccagata aagtatagat tttttgttct aaatccaaat accctagatt aactttttct
    32641 aaagccccca cttgcctttc caaacgttct acttttgaga ttttctgacc aacaaaaccc
    32701 aaatccaaat tttctttgat tgattggttt tctaagaggc cgaaattttg aaagagatag
    32761 cccatctggt ctcgaaaata ctcacgagtg ggaatggttt ttaaatcttt cccctgatag
    32821 agaacccttc caccatctat cttttctagc tttcccaaga tattcagcag cgtcgtcttt
    32881 ccgcttccac tctttccgat taaggcataa accttgccct tctccagctt gagattcaaa
    32941 ccagagaaaa tcgcgcggtc attaaatttc ttttccaatc cttgaatatc aatcatctta
    33001 ttttcctttc aatactgcca tgctaccagc ttcttctttt ttgtcctgcc ttactaaaat
    33061 caagagggcg ttaagcgtaa acaaagctac aactagagcg ctaatcaaac catctcttgt
    33121 caaaatacta gataggacta agccaagcaa gagaactcct ccttgcgcca gtaaatactt
    33181 gccatgaagc tcatagattg tcataccagc aagacgttta atcataagct cccgtctgaa
    33241 ctgctcaaaa tagagaagat tcatggaatc aaataacaag atagccgtag acagggtcaa
    33301 aatcgtccca ataaggagag agtaaaactc cacccgtttg tcatttagta ccttggcaaa
    33361 aaatagctgg ctttttacca agtaagaaac cttgtgatac agaccttgct cttttagagc
    33421 tgtgatgctg tctccatatc gatctagttt caaggcacta ttagccgtag ttccccacaa
    33481 catccctgca acaggtcttg ttccagtcgc ttgcggcgtt agaactacaa taatcggatc
    33541 ttttaggtac tggcgtgttg tcttgtaccc atcattatag aggaaacgtt cctgtcctgt
    33601 ttctgtaaaa gctagcctta cctgtgggag gtagtgtttc tgactcgtca cttctacact
    33661 ttcagatgaa aaattttgca ggtaatctgt aaacaatcct tggtagtaga cagactgctc
    33721 tcgcaagctc tcaggcaaga tcagcccaaa ctctccctca gacaagtttt gcatcttgtc
    33781 cataaactct gaagaaacgg taatcttttc ttctatcaga tagcgtggtg agacatagat
    33841 aacattccct gacggtgtgt agtcactgag acgattgcca tctaggtcca cttctgctcc
    33901 atctgagaaa ttgtcaacat tgctcataat ataaaaagag tctgtattgg ctaaccgttc
    33961 ttcagtaaat gtctgccact cacgattatc cttacgcgtt ccttcttcat cggcaaatgc
    34021 actagaccaa ccaaaggata gacggtaacg gtctgaggac tggctccatt tattgctagc
    34081 tctctccatt tcctgcattt cacggtagtg gggtaggaga gctgtcgcac tcgatccgac
    34141 caccaataca gctaagagtt gccccaccat catcaatgtc atcatacgtt tgagagggag
    34201 tttccctttc aatagatcca ccagactatt ttcctgtaaa ccaagtagat ggacgacact
    34261 tagtaaggta gaaatccctg ccaaggtcaa tccatagagt agaagagcaa tgatgaccag
    34321 ttgcaccgtt gccataaaca aggcaccttg ataccagaga atccccaatc ccaaaagact
    34381 ggataccagc actgagcaga taagctgtct cacatcttct aacactggtc tgagagcaac
    34441 tccaaacaag ctctcaccag ctattaagcg aatccctgct tgacgaaggg attttatccg
    34501 ataaatcagg gtcagactca taaaggtcag cagaaaaata gctaaactca gtagcaccat
    34561 aggggtggcc gtcaatagta agactatcga aaatggatct tctccattcg aaacaaagcc
    34621 ttgatagcca agttctttca aggtggtctg taagctcact ccatccaaac ttcctgacac
    34681 aatcaagtaa gaccctaata aatcactcgt ttctgcactc tccttggagg aaatggtcag
    34741 accttctgga agctctccct caccataagt tgcataggta aagcgtgttt ctccagcttc
    34801 atttggctca acgattcgac gggcgatgag actattatgc tctaccgcca agtgactcaa
    34861 agcctctgtc acctcttcgc gactagctac tggttgattt gtcatcattc ctgtcacatc
    34921 aacagaagga tagttaccaa ataaaatctc ttctcgatgg tcaacggaag ttatcaccat
    34981 ataaagcgat accaatacca ttgaaatcaa aataaataaa cgtttcatca tttcctccaa
    35041 aaagttactt ggtcacttag tgagaaggtg accaagtaaa gctaaacaat agggctatac
    35101 cattctaaac attatagtag aatgcaactt tctctcccca agaagtacga atccatgcac
    35161 gagaagtccc tccagcacca gcatatccct tgtcagatga accagttttt ctgctaacaa
    35221 ctgttgaact atggtatttt gaagggtgat agtagtttga gtaagcacca ccgttacctg
    35281 aaccataagt ccaaacacca ccttctgggt attgaacggc tgcagaggca actgctacac
    35341 ttccacctaa tgttgctgca atgctcgcta caagagctaa ttttttaact gtttgtttca
    35401 tattgatact cctctatttt tgattacaag attgttgagt tacttgctcc tctttccatt
    35461 atcaacgttg atactattat attaccaaat gatattctaa aattatttgt ttttctctaa
    35521 attgtcaaaa tagcaccctg aaatgaactt ttatagtcat tatactccat ctttatcaca
    35581 ctatcaagga catcaatgtc cttaaaatct aactatttca tattattttt agcctatatc
    35641 taaaaaaaca gttctaaaga cgaactttag aactgttttg atacgaggac aaggacattt
    35701 ttgtcactga ttcactatgt ttataaatat tttttgacat cctcttgcca ttcctctgtc
    35761 aatttcttta ctagaaattc atctccaatt agctgcgcaa atgttttaga agactgataa
    35821 aatgattcag ctaaactaaa atctctttct tctcttaatg cttgcttcca caaaaacata
    35881 aatacaagag gtttcttttg ataatcttga gttttatcca taatttcttg taaacacgat
    35941 agataatcat taaaacaatc agttactcct accttttcaa gacaacacat tcctgaaata
    36001 agagtatctc taattataaa gaagttttct aatttagtta cctttttctg ttccaaaaga
    36061 aagagcatta gcttttcgat ttgatttata aatttggcaa gatcttttct aatgagcatt
    36121 tgataaaaaa acaaacgaat caacaacata tcatttgttg aataaacttc tttttctatg
    36181 atctgagaca tatgttcctc aagtattaac tctgcatatt caggccttct agttctagaa
    36241 gtatccaaac acgcctgcaa tacttcacat gctaattgtt cttctttagg aagattatca
    36301 aagtatgttt tataaatctc ttccaaacac gcttccttct tatcgtactc ctcttcttta
    36361 ccatagattg gttcacgtaa aatctggtat ttcaattcta aataagcagg aggaagagct
    36421 gaaaaatccg gcataaggct ataaactgga actcctagcc ggcgagcaat ataggctaac
    36481 ttgggcaaac tcggttgcga agctccactt tcaattcgcg acagttgacg aactgtcagt
    36541 tcttgctcat ctccacaaaa atctggacga ctaactcctt tttctatccg aatctcttta
    36601 attttttgac caattaacat cagacgcctc ctcttctacc tgcttcgaaa aatactgtga
    36661 aacttaaaaa attgtaacgg tcacatcttt cctactcata agatttcata gcttcttcca
    36721 cttctgccaa agtaacccca aacaactcta ggcgtttgag gagttgcttg ccgttagaat
    36781 agccgattcg gagagtctct ccgagatatt ccctacgctt acggctgtct gcccctacta
    36841 gaaaaccaag gcgaatcaag tcgctacgac taatgtcaaa ctgactctca tgttcaaatt
    36901 gttctgtcac ctgagctaga gccgttttca ggtcttcata gctggcatgc tcaattccca
    36961 gagaacgccc cttggtcttg gacttgggaa cagcttcatc tcgcttgaga aaggcatgct
    37021 gaactgttgg aatgaccgtc atgatcatgc gccgaatccg ttccccatta aaatctgggt
    37081 ctgtaaagac aatgactcca tgacgttggt gcaggcgctg aatccgctct atatcctgat
    37141 cattgatggc agaacctcga gtctcatagg tctccacatc gaaataacgt ttgagattga
    37201 ccgtatcatc acgcccttca accacaatta cttgggaaat tttctctttc attacttgct
    37261 gtccagtcca aaaattcgtt ctgcatttgc agtcgttgct accgccagct cttctgtcgt
    37321 cataccacgc aagtcagcga taaagtcgac cacatagcga gtataggctg ttttattttc
    37381 acgaccacgc ttgggtacag gtgctaagta aggcgcatct gtttccacca acatcttgtc
    37441 caaaggtaac tctttagctg cttcttggag gtcagttgcc ttcttaaaag tcaccactcc
    37501 tgagaaggaa atggtcatac caagatccac aaacttctct gcccactcaa gcgtccctga
    37561 aaatgaatgc atgataccac cacgaggacc aacgccctca ctcttgataa tctcataggt
    37621 atcttccagc gcatcacggg tatggacaac aaaaggcaaa tccaagtcct tagatagctg
    37681 aatctgacgg cgaaaaacct gctcctgcac ctctttgggc gctgtcatcc aatggtaatc
    37741 taagccaatt tcacctaaag ccacaacctt gggatgtttt aacttatcca acaagtaagc
    37801 ctcaacttcc tctgtataag taccagcttc tgtaggatgc caaccaatag tcgcatagag
    37861 ctgctcatac tcatctacca actccaaggc acgctcaatc gtcggtttat caaaaccaac
    37921 aatattcatc tgtgtcacac ccatctcagc agccaaggca atttcttctg cctcacgacc
    37981 tgcaaattct tctacattca agtgtgtatg tgtatcaaaa atcatctctt ctaacctcgt
    38041 tttctatctt ctattatacc aaaaaagagg aggggcacct aatttttcgg tttcccctcc
    38101 tctcttcaat agagagctat tctgctatct tttctatccg atattgccca tctcctattc
    38161 cacagttaga gacagaagag attggctaca ttgatagact attcctattc agctaaagta
    38221 tgtgattatc ttgggttctc acttttctca cccatcacta ggattgatga cttctcaaaa
    38281 tcccccttat aatctaactt taagtagaga atagaatttt ctagctgttc cattttctac
    38341 gtctagtctt tcttcctagc aaagcaaaac cactggttgc cgccactaga ccaagactag
    38401 caagtgctgc acttgatgct gaacctgtgt taggtaattg tttgccagca ggtgactggt
    38461 aggtaacatc ttgcattgtt cctgcagttg cttgcggtgc acttgttgtc ttaggagcag
    38521 cattaggagc cactggtctc ttaagaactg taaccatggc aatggcttgc actccaatcg
    38581 tttctgcttc cttcacatct tccatagttt tcgtattttc aatctctttg agagctgctt
    38641 gtttttctgc ttccactctt gctaaaagtt ctgctttttc tttatcagaa agcggtgcgc
    38701 ctttgatttc atcctgcttg tccttggctg ctttttcaat ggcattttta gctgattctt
    38761 tttcagtagc taattgctta gaagcttgtg attgagctga gttttgtgaa cctgtgtgag
    38821 ctggtccacc tgcctggcta ccaccgcctg cattcgcatt agcatctgag cttccagtat
    38881 tgcctccctt atctacacct agtgtagttt ctggcttata ctctggtgta gcttcttgag
    38941 ttacagattc acctttcgca gattgttgaa ctgtatcttt tcctagaatc gtcactactg
    39001 aaccatctgg gaatgtgatt gttgctgtac catctccagc tacttcaact ttatagcaaa
    39061 atgaaacaat aacaggacaa atcgatcagg acagtcaaat cgatttctaa caatgtttta
    39121 gaaacagagg tgtactattc tagtttcaat ctactataac atcgcttccg aatccatttg
    39181 catctactga acttttttac aaaaataaaa atcagtagac tcgagttcct actgattttt
    39241 gatagaattc gtttggatta tgcagccaaa actttgcgtc ctttacgacg acgagctgcc
    39301 aatacgcgac gaccattttt agttgacata cggttacgga atccgtgttt gcgcgcacga
    39361 cgaagtttac ttggttgata agtacgtttc acgatgaata cctcctcata gattttgtat
    39421 tcgtttagcc ggctataaag tgatcagtta ctaaacatac tttactattc tatctgattc
    39481 tttcactttt gtcaatagct ctaggcaaat gtttccagct ttttcgaatg caagccctat
    39541 ctacgatact gtttcaagaa acgagtcatc ttttcttgga tttgggctaa ctcatcaaca
    39601 cgaggaaggt aaacgatacg gaagtggtct ggttcctgcc agttaaagcc tcgaccatga
    39661 accaagagaa ccttttcctg cttcaagaaa tcaaggacaa actgctcatc atcatcgata
    39721 cggtacatat tgcggtcgat ttttgggaag atatagagcc ccgccttggg tttaacggca
    39781 gacaaacctg gaatatcttg aatggcatta tagatgaaat ttctttgctc gtagattcgt
    39841 ccaccaggaa gaagcaattc atcgactgat tggtgacccc ccaaggaagt ttgtacgact
    39901 tgttgggcca aaacgttaga gcaaaggcgc atattggaca gcatattgag cccttcgata
    39961 tagcccttaa catgagtctt agggccagac aagaccatcc aacccacacg gaaacctgct
    40021 atgcggtggg attttgacag accattcatg ctgacacaga agacatctgg tgccaagctc
    40081 gccacaggcg tatgcacatg tccgtccatt accatgcggt catagatttc atccgcaaag
    40141 ataatcaaat cgttttgacg ggcaatctca ataatctcca gcaagagttc cttaggataa
    40201 agggctccag ttgggttatt tggattgata aggacaattg ccttggtatt ggaagtgatt
    40261 tttgacttga tatcgtcaat atctgggtac cattccacag cttcatcaca gatatagtga
    40321 acggcatttc ctccagctag gctgacagcc gccgtccata gaggatagtc tggcattggc
    40381 actaagacct catccccatt gtccaaaagc ccctgcatgg acatgacaat caactcactg
    40441 acaccatttc caaggtaaat atcatcaata tctacgtttg ggaatttctt cagctggcaa
    40501 tactgcatga tggccttacg ggctgagaaa atccctttgg agtcagaata gccttcacta
    40561 tcacgcgcat tcataatcaa gtcatgaatg acctcgtctg gcgctgtaaa gccaaattct
    40621 gctggatttc ctgtattcag acgtaaaatc ttttctccat tcgctcgcat ccgcatggct
    40681 tcttccaata caggaccacg gatatcataa gcaacatgct ctaacttact agacttgtta
    40741 tattctttca tcttgtttcc tcaattcatc aggatagtaa cattatacca ctagaaagag
    40801 aatgcgacaa gtttactgaa atgtgttact agtttcgtat agaagaaaaa ccttgctaaa
    40861 ggcgaggtta agaacgtaga gatagcaggt attttgcaaa gacacatcac ataccaaaag
    40921 ataaacctag aaaaagcaag cctagaaagg agtcataaag aagattaaac atgaggaaaa
    40981 gcccccatat catcaagtaa tcccaacgcc cacttcgttt tgcaactaga aataagatta
    41041 gatggtagag tacatgaaaa actaaaaatc caataaaact tggataaaga agcggtacca
    41101 gactctctaa ttgacagatc atgatcactt ctaccaagac tgaaactagg ataattccat
    41161 aataaaggaa atttgatttt tgaaaagagt ttttcatcat tctcccttcc ttcacttctt
    41221 tcctgctatc ctttctttta ttttatcata tatttatata gagtttaagc cctaatattc
    41281 ttttgaaaaa tacttttttt gctttacttc tatagtgaaa aggtttacaa ttatagtaag
    41341 aaaatttcag gaggtttcat tatggcacaa cgttaccaaa atatcatggt cgcaatcgat
    41401 ggttctaagg aagcggactt ggcttttgtc aagggagttc attctgctct acgaaacgac
    41461 gctaaactca ccatcgcaca tgtcattgac acacgcgctc tccaaagcgt atccaccttt
    41521 gatgctgaag tttacgaaga actccaagtc gacgctgaaa gtctgatgaa agagtacgaa
    41581 aaacgtgcta aagatgctgg ggtagcagat gttcatatcg tcattgaaat gggaaatcca
    41641 aagaccctgc tagcacgtac tattccagat gccgaggaag tggacctcat cctcgttggc
    41701 gcaactggtc tcaacgcctt tgaacgcctc ttggtcggct cttcatctga atacatactc
    41761 cgccatgcta aggtcgattt gctggttgtg agagaacaag aaaaaacctt ataatcacaa
    41821 agaaaaggag cccctagctc ctttttgttt acgatttatt tctctcttta tggcgttcgt
    41881 aagccttgag ctggcgctgc agttcctttt taatagcagg ttctggagca tatttttctt
    41941 cccaattatc tggttttaag attttatggg tcactggatc aaaatgagcc ttgccatctg
    42001 gaaaaatttt ccccatattg gcctgatgga caatatcaaa aatacgttct gggtccaccc
    42061 ccatcaagac aaaactgccg taggtgaagt aaagcgtgtc aatcaaggca tccacttgcc
    42121 ctatcaaatc ttgctgagca ggtgtcttct tggctacttt atctgctgcc ttatcaaggg
    42181 cctgatgaag ttgcgataca gcttgaccaa aatcttcttc agaaggactg gctgctcgaa
    42241 caaactccac caattcttct attttaaaac cagccctatg ggttgcaccc tctaaatccc
    42301 aagctcgagg ttcttcttgg gttcgttcat ccatcatgtg gtggaaggtc ttgaccttat
    42361 tgaaatgata gtcacggctg acaaagactt tttctgaaga caaaacacca aaatgttcca
    42421 aggccttgtg gatcccatct tgttgattgc tagtggtaat gtgcttggca gcttccttga
    42481 cactgctact accatttccc atagcgaccg acataccgac gccagccagc atttcaaggt
    42541 cattatctga gtcaccaaaa gccatgactt gattgaggtc aaagccatat tctttcccaa
    42601 ctcggcgaat gccttctaat ttagaatttc cctgattgat gacatccgat gcaaaaggat
    42661 tgctacgtgt caatttcaag tcttcaaaat cagctgccgc cttctcagat tcttctggtg
    42721 tcatcagcat caaaacttgg tagataggct gattcatcag gtgaagcagg tcctcttcct
    42781 tttggggaac aaccttgctg accatgcgat taaaagactg actcaccgtc cgagttaaaa
    42841 cagagggaac gaagcgacta attcgttggg aaaaagaacc cagaccaaag gacatgattt
    42901 tagaacccaa catggcatcc ttggtcccta gggcaatctc cgtgccctct tttttagcat
    42961 agctaattag atggcgcaaa tgtaacttgg aaatagggct cgtgaacaag actctgtctt
    43021 tactaaagat atactggcca ttataggtta ccgcaaaatc cagatccaaa tcgtccatca
    43081 attccttaac aaaaaaaggt cctcgccctg tcgctacgcc aactagtacc ccttgttctt
    43141 tgacaatctt aatcgcatcc ttagtggatt tcaaaacact cttgcgattg ttgaccaagg
    43201 ttccatcgat atcaaaaaaa acagctttga cttccatcct atcccaatct ccccttttgt
    43261 gatacaatga ttataccaca tttcagaaag agttagtaaa tcatgcctaa gaaaatcctt
    43321 gttttacata cgggtggaac tatttccatg caggccgatg cttctggcgc tgttgtgacg
    43381 agttcagata atcccatgaa ccatgtgtcc aacccacttg aaggaatcca agtccacgcc
    43441 ttggactttt ttaaccttcc aagtccccat atcaaaccca aacatatgct ggtcctctac
    43501 cagaaaatta aagaggaagc agataactac gatggagtgg tgatcacaca cggaaccgat
    43561 actttagagg aaacagccta tttccttgat accatggaag ttccccatat gcctatcgtt
    43621 ctaacaggag ccatgcgtag ctccaatgag ctcggtagtg atggtgttta taattaccta
    43681 agtgctttac gagtggccag tgatgacagg gctgctgaca aaggagtttt ggtcgttatg
    43741 aacgatgaaa tccacgctgc caagtatgtc accaaaacac atacgactaa tgtcaacacc
    43801 ttccagactc caacacatgg ccccctcggt ctcatcatga aacaggaaat cctctacttc
    43861 aaaacagctg aacctcgtgt tcgctttgac cttgatcaca tacaaggttt agtccctatc
    43921 atctcggctt atgctggtat gacagatgag ctgattgata tgctggattt agaacacttg
    43981 gacggtttga ttatccaagc cttcggagct ggtaatattc ccaaagaaac ggctcaaaaa
    44041 ttagaaagcc ttctgcaaaa aggaatccca gtcgctctgg tatcacgatg ctttaacggt
    44101 attgccgagc ctgtttatgc ctaccagggt gggggcgtac agttgcaaaa agcaggcgtt
    44161 ttctttgtta aagaactcaa cgcccaaaaa gcccgcttga aactcctcat cgccctcaat
    44221 gccggactaa caggacaggc tttgaaagac tatatggaag gctaatactc ttcgaaaatc
    44281 tctgcaaacc acgtcacgtc gccttaccgt atgtatggtt actgacttcg tcagttctat
    44341 ctacaacctc aaaacagtgt gttgcgcagc ctttaaccag ccgcctagtc cgctctatgg
    44401 tattcattaa gtcaacatct cttgtttaag agcacaaaat caggaaatct tctcgattcc
    44461 ctgatttttt ctatttacgt tttcgtgttg agctacgttc tgtcaaacca tgaggtaaga
    44521 gaacttcacg ttcttccaac tcttccttat gcataatctt ggtcaacata cgcatactaa
    44581 tggcaccaag gtcataaaga ggttgggcaa tcgttgtcaa gtttggacgg gtaaagcgtg
    44641 agatttgtga atcatcacta gtaataattt caaaatcttc tggcacagaa acacccttat
    44701 cagccaaacc gttcaagact cctgctgcca actcatcacc tgtcacaact gctgcagttg
    44761 catttgatga aatcaaacgc tctgctaagg cgtaaccatc atcatagcta tatttagatt
    44821 caaataccaa accctcacta taagcgattc ctgctttttt caaggtttcc ttgtagccaa
    44881 ctaaacgaac cttaccattg atgtcatcca ctagcggacc gctaacgaaa gcaatacgct
    44941 cattttcttt agcaaggtaa ctcactgcat caattgttgc ttgcttatag tcaatattga
    45001 cacttggcaa ctggtgctca acatcgacag ttcctgcgag aacaatcgga gtacgtgaac
    45061 gcgaaaattc tgagcgaatt ttatctgtca agtgataacc catatagata atgccatcta
    45121 cctgctttga aaagagggta ttgacaacag aaacttcttt ctcgttatct tcatcgctat
    45181 tagctaggac aatattgtac ttgtacattt ctgcaatatc atcaatcccc ttagccaaac
    45241 tcgaaaaata accattggta atatttggaa tcacgacacc gacagtggtt gtctttttac
    45301 ttgcaagacc acgcgcaact gcatttggac gataatccaa gcgatcaatt acctctagca
    45361 cttttttacg ggtattctct tttacatttt tattgccatt gaccacacgg ctgaccgtcg
    45421 ccatggaaac acctgcttca cgagcgacat cataaatggt tactgtatca tctgcattca
    45481 ttccttttcc tgtcctttct atctcacaca ttcttttaca agtagaggta ctgattgaag
    45541 ctctatatct acttacaaaa gtgaagatgt gaaaatttcg ttttcatatt tctacttatt
    45601 ccattctatc actaattgta aacactttca agtgtttttt gaagattgat tgaaaaaatt
    45661 tcatagaaaa cctaggttta gctccttgct accaccttag actaaacaaa aaggaggaaa
    45721 ctaagccctc ctaaagttat agtaaaatga aataagaaca ggataaatcg atcaggacag
    45781 tcaaatcgat ttctaacaat gttttagaag tagaggtgta ctattctagt ttcaatctac
    45841 tataggtatt gttccattca ctaccgtcaa ttttagcaca tagtcttcat gaaaatatta
    45901 tatcatcata accaaccaga ttcttttgcg atattagctg cctctgttcg attaccagca
    45961 tccaattttg aaagaatatt ggtgacatag tttcgaatag ttccgtttga gaggtaaagc
    46021 tgatctgcga tttcttggtt ggataagccc cgggcgatcc cctttaagac agcaatctct
    46081 tgttctgtca acggattggg acgggtcatc accacttcca tcaattcagg cgaatactcc
    46141 ttgcgtcctt cgaggacggt gtgcaaggtt tgcatgaggt ctgcaacgct tcgttccttt
    46201 aatacataag catccactcc agccttgacc gcacgttcaa aatacccagc acgcttgaag
    46261 gtcgtcacca caaccacctt tgtttcaagc ctttctgatc gtatccactc caagacttca
    46321 agacctgtct taacaggcat ttctacgtca aggatggcga tatctacaga ctccttttct
    46381 aatagttgga ttgcttcttg cccattcttg gcttgaagga cagactccac atctggttga
    46441 agcgtgagca attgacacat ggcatctcgc aacatacttt gatcttctgc gactaatact
    46501 ttcatcttag tttctctcct tataaggtag tcgaacttgc acttccgttg gatgtttctg
    46561 actgattaca cttacttctc ctgaaaatgg aaaaacacga tctcggattg tatggagctc
    46621 atctcctttt agaaaagcaa agccgcagcc atcatcactt actgttaaaa tgagttcctt
    46681 ctctgtccgt tctaatttta agtaagcttt agacgctttg gcatgtttga tgatattggt
    46741 caccaactca agcaaaatca tagaagccat tgactccaat tcttgagtaa ggctagcagt
    46801 atctagttgg ttatccgttt ccacctcaat tccagcaatt tctaacatct ttttcacagt
    46861 ctctagttcg gatgtcaaag ttctagactt aagattttcc acaatggttc gaacttcacg
    46921 cattgattct ttgctaattt gctgtatttc tcttaattcc ttttccactt gtggataagc
    46981 ctgcatttga aatagctgca aggctagatc tgtcttgaca ctaagcatag caaaggtatg
    47041 tcccagacta tcatgcaaat cctgaccgat acgattgcgc tcattttctg ctagcaatag
    47101 atttatctgg gtattttgct tgacctgagc ttctttcaaa tcctcgacaa ggcgaattcg
    47161 aaccgagccc aaagtcatca aatcgacaaa agtaagaatt acaagcatat agactagaaa
    47221 ctcaacttcg attctctgaa aaatcaaaag tcgccccaca acaaggactt gagcaaggag
    47281 aaatgtccat acatgtaaag actttaaact acgtacgcca aaatgataaa ttaagagatt
    47341 ggaaaggaaa aagaaaaacc agatataatt cccagcaaca aaggcggtat tcccagctac
    47401 atagaccagc atgatccccc agaaaagcca tgatatgcgc tggttcttag ttattaaaac
    47461 acccaaatac gtcactacaa atagaatatc aaccaataaa tgccaagcag gaagctcccc
    47521 agtcactaca ggtaggatgg ggaaaatcat aaaaattaaa cttgcccaaa acatatagtg
    47581 tatgcttttc agtctttcaa gcattaagca ttctccttat gaccttgaag gtaaatggtc
    47641 aaaccaaaca aaactgctga aaaaacaagt agataaactg tggctgatag attgatgcca
    47701 ccctcgttta agaaggtctt gagcaactcc atcaattgat aggtcgggag acacttacca
    47761 actgcttgca tccagtctgg aaataaagaa atgggcatcc agagtccgcc taaaacagcc
    47821 aatcctagat aaagaagatt gcccacaaca gacatcagct gactagttgg taagagagtc
    47881 aaggtcaagc caagtgctac aaaagcaata ctccccacaa tcagcaaaat cgcagctcca
    47941 acccatttta ctagaggcat gtctacacct cttacaaaat gtccaactgt aaaaacaacc
    48001 agaattgaga ccaaataatc aaccagcata cttgttatct ttgatagata atattctacc
    48061 atatttacag ggctatgacg caatgttttc tgccagttgt tcatcttatc ggtatgtaaa
    48121 acagctggaa atgagaggat agttgtcgac atcatggaaa aggcagtcat ggagatgagg
    48181 taatcacgca taaaattcgc gagttcacct ggtgtgtcct gatagatacc agaaaaaaat
    48241 aaatagaaag ccgtcggcat ccctaccgac aatagataat agattaattg tcgtttggtc
    48301 aataaaaatt ctatcttact aagtgctatc catcgtttca tcttagttat ctcccttctg
    48361 cgtctcttca aagattgtat tcaacaaact acgattatta acttcgattt cttgcatcct
    48421 acatcctgct tgggctaata gttcccagaa agcatctgct tctcgagtga ctacttgtaa
    48481 agaatcttgc tttagggtcc agttttcaac caaatttgac tgctctacga cttccttgta
    48541 agctatagga aggataaagt gcttttctat ttcctcgcta cgcatagcta gaggcgtcgt
    48601 atctcgaatc aactctccct tatttaagag caaaatgcgg tctgcagtgt gttccacttc
    48661 ctcaatataa tgggacgaat agagaatggt gactccttgc gcttttaact cctggacaat
    48721 ttcccaaaaa cgttgacgag ttgaggtatc catggacgca gtaggctcat ctaaaaaaac
    48781 aatctttggt cgcccaatta aggtcaagac gaaagaaaag agacgctttt gaccgcctga
    48841 taatttttct gccaactgtt ctttttgttg cttgacaaac tgcaatagtt gatcaatttc
    48901 ctgattgctc aaaggatttg gatagatacg ttgaaagaaa gcaatcaact ctttaacttt
    48961 taatttctga acgattacat tttcttgagg gaggtaagcc ctagtatagt ctaacttaga
    49021 actcgtcact ggtaaacctt gaatagatac ttgaccgctt gtgaccagtt tatctccaag
    49081 caaacaatct aagagtgttg tctttccggc accatttgga ccaattaagg caacacattc
    49141 accatcgttg atttcaaagg agatattccg caaaatttcc ttgtctttta ttttcttact
    49201 caatttctca actttaacca ccgtcatgag actctccttt caaccactcc attcccataa
    49261 ggaaaacgac gaaaatcata aatccaaacc ccaaagcacc acgaatgaat tggcgaagca
    49321 aggcttgatc aaaccaatca gtaaacattt ccactaacca taccaagagt gacaggccga
    49381 taaagaaata gatgatccct ctcttcattc ctcaaactcc tttttcacat ctctgactaa
    49441 tttcaaacct tctctaacaa gccaagacat gattccaaag ccagcaaaga ccttccaagg
    49501 aaaatggtag aaatcctcat ccaatcccga aaacatgaga taggtcataa ctcctgctac
    49561 tactaaactt actgcgataa tcattttatt tctcatctct tcttccccca tttcatacta
    49621 caattatagt cttttaaaat cagaggagac agaagcttct gtcactaaaa aatatgacaa
    49681 atgtcataaa aaattctgtt caaaacaagc aagatacact atacaataaa acacaatcag
    49741 aaaaatctaa ggcaacttcc tcaaaagaga tatcaaaccc aattcacacc ataatgtaaa
    49801 ctaatactta tttaaaatca aaaagagtaa a
//
LOCUS       DAVLDI010000009        48608 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLDI010000009 DAVLDI010000000
VERSION     DAVLDI010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.009"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            165..2798
                     /gene="polA"
                     /locus_tag="VXD01_000483"
     CDS             165..2798
                     /gene="polA"
                     /locus_tag="VXD01_000483"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV0600925.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKSYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            2883..3320
                     /locus_tag="VXD01_000484"
     CDS             2883..3320
                     /locus_tag="VXD01_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV0600926.1"
                     /translation="MSQEFINPSDGVIRRYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLLDVARDFLKADA
                     KIFWAQLGLESLEAEEILRAGGCDDIVMNRCIKREHTRLIGEA"
     gene            3355..3435
                     /locus_tag="VXD01_000485"
                     /pseudo
     CDS             3355..3435
                     /locus_tag="VXD01_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(3640..4650)
                     /locus_tag="VXD01_000486"
     CDS             complement(3640..4650)
                     /locus_tag="VXD01_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV0600927.1"
                     /translation="MSFLSKNGAGILVCLLISILSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            4799..5968
                     /locus_tag="VXD01_000487"
     CDS             4799..5968
                     /locus_tag="VXD01_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0600928.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            5965..6735
                     /gene="recO"
                     /locus_tag="VXD01_000488"
     CDS             5965..6735
                     /gene="recO"
                     /locus_tag="VXD01_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV0600929.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            6732..7724
                     /gene="plsX"
                     /locus_tag="VXD01_000489"
     CDS             6732..7724
                     /gene="plsX"
                     /locus_tag="VXD01_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV0600930.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVRLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTFPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            7730..7963
                     /locus_tag="VXD01_000490"
     CDS             7730..7963
                     /locus_tag="VXD01_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0600931.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            8009..8299
                     /locus_tag="VXD01_000491"
                     /pseudo
     CDS             8009..8299
                     /locus_tag="VXD01_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            8502..8660
                     /locus_tag="VXD01_000492"
     CDS             8502..8660
                     /locus_tag="VXD01_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HEV0600932.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAILGGV
                     AYAATCWW"
     gene            9379..11532
                     /locus_tag="VXD01_000493"
     CDS             9379..11532
                     /locus_tag="VXD01_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV0600933.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKDQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAALSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            11545..12894
                     /locus_tag="VXD01_000494"
     CDS             11545..12894
                     /locus_tag="VXD01_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV0600934.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTVKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAEINLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            13064..13771
                     /locus_tag="VXD01_000495"
     CDS             13064..13771
                     /locus_tag="VXD01_000495"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV0600935.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            13973..17698
                     /locus_tag="VXD01_000496"
     CDS             13973..17698
                     /locus_tag="VXD01_000496"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV0600936.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLA
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFTQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNRVKLDGHKLDSAFQGTLEEVYPTEFTRAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            17791..19233
                     /locus_tag="VXD01_000497"
     CDS             17791..19233
                     /locus_tag="VXD01_000497"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV0600937.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            19270..20292
                     /locus_tag="VXD01_000498"
     CDS             19270..20292
                     /locus_tag="VXD01_000498"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV0600938.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            20289..20834
                     /gene="purN"
                     /locus_tag="VXD01_000499"
     CDS             20289..20834
                     /gene="purN"
                     /locus_tag="VXD01_000499"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV0600939.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            20918..21427
                     /locus_tag="VXD01_000500"
     CDS             20918..21427
                     /locus_tag="VXD01_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0600940.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITNLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            21452..22999
                     /gene="purH"
                     /locus_tag="VXD01_000501"
     CDS             21452..22999
                     /gene="purH"
                     /locus_tag="VXD01_000501"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV0600941.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            23121..24383
                     /gene="purD"
                     /locus_tag="VXD01_000502"
     CDS             23121..24383
                     /gene="purD"
                     /locus_tag="VXD01_000502"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV0600942.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTAIYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQLILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLDYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            24786..25274
                     /gene="purE"
                     /locus_tag="VXD01_000503"
     CDS             24786..25274
                     /gene="purE"
                     /locus_tag="VXD01_000503"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV0600943.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            25261..26352
                     /gene="purK"
                     /locus_tag="VXD01_000504"
     CDS             25261..26352
                     /gene="purK"
                     /locus_tag="VXD01_000504"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV0600944.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIETC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            26362..26589
                     /locus_tag="VXD01_000505"
     CDS             26362..26589
                     /locus_tag="VXD01_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV0600945.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            26652..27950
                     /gene="purB"
                     /locus_tag="VXD01_000506"
     CDS             26652..27950
                     /gene="purB"
                     /locus_tag="VXD01_000506"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV0600946.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(28005..31943)
                     /gene="strH"
                     /locus_tag="VXD01_000507"
     CDS             complement(28005..31943)
                     /gene="strH"
                     /locus_tag="VXD01_000507"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV0600947.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMDFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQEEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(32259..32975)
                     /locus_tag="VXD01_000508"
     CDS             complement(32259..32975)
                     /locus_tag="VXD01_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0600948.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            33323..35110
                     /locus_tag="VXD01_000509"
     CDS             33323..35110
                     /locus_tag="VXD01_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV0600949.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFKTLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            35107..35583
                     /locus_tag="VXD01_000510"
     CDS             35107..35583
                     /locus_tag="VXD01_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0600950.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            35611..36516
                     /locus_tag="VXD01_000511"
     CDS             35611..36516
                     /locus_tag="VXD01_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0600951.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            36503..37318
                     /locus_tag="VXD01_000512"
     CDS             36503..37318
                     /locus_tag="VXD01_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0600952.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            37325..37729
                     /locus_tag="VXD01_000513"
     CDS             37325..37729
                     /locus_tag="VXD01_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0600953.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            38023..39189
                     /locus_tag="VXD01_000514"
     CDS             38023..39189
                     /locus_tag="VXD01_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV0600954.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVMITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            39305..40342
                     /locus_tag="VXD01_000515"
     CDS             39305..40342
                     /locus_tag="VXD01_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV0600955.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            40549..41403
                     /locus_tag="VXD01_000516"
     CDS             40549..41403
                     /locus_tag="VXD01_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0600956.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGEKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGI
                     VTRIRLAR"
     gene            41553..41793
                     /locus_tag="VXD01_000517"
                     /pseudo
     CDS             41553..41793
                     /locus_tag="VXD01_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
     gene            complement(42124..42216)
                     /locus_tag="VXD01_000518"
                     /pseudo
     CDS             complement(42124..42216)
                     /locus_tag="VXD01_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(42252..42548)
                     /locus_tag="VXD01_000519"
     CDS             complement(42252..42548)
                     /locus_tag="VXD01_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0600957.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLISQGLTVTNVEGGMNAWPGQVE"
     gene            complement(42538..42699)
                     /locus_tag="VXD01_000520"
     CDS             complement(42538..42699)
                     /locus_tag="VXD01_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV0600958.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            42769..43533
                     /locus_tag="VXD01_000521"
     CDS             42769..43533
                     /locus_tag="VXD01_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV0600959.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLVGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(43773..43925)
                     /locus_tag="VXD01_000522"
     CDS             complement(43773..43925)
                     /locus_tag="VXD01_000522"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600960.1"
                     /translation="MRTKASLRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTAR"
     gene            44143..45522
                     /locus_tag="VXD01_000523"
     CDS             44143..45522
                     /locus_tag="VXD01_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0600961.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            45536..46201
                     /locus_tag="VXD01_000524"
     CDS             45536..46201
                     /locus_tag="VXD01_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV0600962.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            46331..46411
                     /locus_tag="VXD01_000525"
                     /pseudo
     CDS             46331..46411
                     /locus_tag="VXD01_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            46557..47006
                     /locus_tag="VXD01_000526"
     CDS             46557..47006
                     /locus_tag="VXD01_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0600963.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVEILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGVVNCGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDAFVTNFVYEKEGQSRKKSMSYESVLPVRQIFD"
     gene            47163..47573
                     /locus_tag="VXD01_000527"
     CDS             47163..47573
                     /locus_tag="VXD01_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV0600964.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKRIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            47689..>48608
                     /gene="pavB"
                     /locus_tag="VXD01_000528"
     CDS             47689..>48608
                     /gene="pavB"
                     /locus_tag="VXD01_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV0600965.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRSNGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVK"
BASE COUNT        13520 a         9325 c        11528 g        14235 t
ORIGIN      
        1 caagatgtac tattatagat tcaatatgct atattatagc acatttttaa atctaggttt
       61 actagattct ctggctctat ctatttattc ggaaaaagtt tgaaaaatac ttgctctagc
      121 tcttcccaat ggtatttttt gattctttcc tttataatgg gtgtatggat aagaaaaaat
      181 tattattgat tgatgggtct tctgtagctt ttcgggcgtt ttttgcgctg tatcagcagt
      241 tggaccgttt taagaatgcg gctggtttgc ataccaatgc gatttatggt ttccagttga
      301 tgttgagtca tttgttggag cgggttgagc cgagtcatat tttggtggct tttgatgcgg
      361 gaaagacgac cttccggaca gagatgtatg cggactataa gggtggtcgg gccaagactc
      421 ctgatgagtt tcgtgagcaa tttcctttca ttcgtgagtt gctggatcat atggggattc
      481 gtcactatga gctggctcag tatgaggcgg atgacatcat tgggacgctg gataagctag
      541 cagagcagga tggttttgat attaccattg tcagtgggga caaggatttg attcagctga
      601 cggatgagca tacggtggtt gaaatttcca agaaaggtgt ggctgagttt gaggccttta
      661 cgccagatta cctcatggaa gaaatgggcc tcacaccagc tcagtttatc gatctcaagg
      721 cgctcatggg tgataagtcg gataatatcc ctggggtgac caaagtcggt gaaaagacgg
      781 gtattaagct cttgctggag catggttcgc ttgaggggat ttatgaaaat attgatggaa
      841 tgaagacttc taagatgaag gaaaatctca tcaatgacaa ggaacaggcc tttttgtcta
      901 aaacactagc gaccattgat accaaggcac cgattgcgat tggtttagag gacttggtct
      961 atagtggtcc agatgttgaa aatcttggga aattttacga tgagatgggc ttcaaacagc
     1021 tcaagcaggc tttaaatgtg tcgtcagctg atgtggctaa gggtttagat tttactattg
     1081 ttgaccaaat cagtcaagat atgctgagtg aagagtctat cttccacttt gagctttttg
     1141 gtgagaatta ccatacggat aatttggttg gatttgcctg gtcttgtgag gataagctct
     1201 atgccacaga caagcttgag ctgttgcaag acccgatttt caaggatttc ttagaaaaaa
     1261 catctctgag agtttatgac tttaagaagg ttaaagttct tttgcaacgt tttggtgtgg
     1321 atttgcaggc gcctgctttt gacatccgtt tggctaaata cctcctttcg actgtggagg
     1381 acaatgaaat tgcgaccatc gctagtcttt atggtcagac ttacttggtt gatgatgaaa
     1441 ctttctacgg taagggtgtt aaaaaggcca ttcctgaacg tgagaaattc ttggaacact
     1501 tagcttgtaa acttgctgtt ttggtagaaa cagagcctat tttacttgaa aaactcagcg
     1561 aaaatgggca attagagctt ctttatgata tggagcaacc tctggctttt gtccttgcca
     1621 agatggaaat tgctgggatt atggtcaaga aagagacctt gcttgagatg caggctgaaa
     1681 atgagcttgt cattgaaaaa ctgactcaag agatttacga gctggctggt gaggagttta
     1741 atgtcaactc gcctaagcag ttgggcgtgc ttctctttga gaaattggga cttcctctag
     1801 aatacactaa gaaaaccaag acaggttatt cgacagcagt ggatgtgttg gagcgtctcg
     1861 ctcctattgc tccgattgtt aagaaaatcc tggattaccg tcaaattgct aagattcaat
     1921 ctacttatgt aattggcttg caggactgga ttttggctga tggaaagatt catactcgct
     1981 atgtgcagga tttgacccag accgggcgtt tgtctagtgt ggatccaaac ttgcaaaata
     2041 ttcctgcccg attggaacag gggcgcttga ttcggaaggc ttttgtgcca gagtgggagg
     2101 atagtgtgct actcagctct gactattcac agattgaatt gcgcgttttg gcgcatattt
     2161 ctaaggatga gcacttgatt aaggccttcc aagagggggc agatatccat acttcgacag
     2221 ccatgcgggt ctttggcatt gagcgtcctg atgatgtgac tgcaaacgac cgtcgcaatg
     2281 ccaaggcagt taactttgga gtggtttatg ggatttcaga ctttggcttg tctaataatt
     2341 tgggaattag tcgtaaggaa gccaaagcct acattgatac ctactttgaa cgttttccag
     2401 gtattaaaaa ctacatggat gaagtggtgc gggaggcgcg tgataagagc tatgtagaga
     2461 ccctctttaa gcgtcgccgt gagttgccag atatcaattc gcgcaacttc aatattcgtg
     2521 gttttgcgga gcgaactgct atcaactcac ctatccaggg ttcggcagca gatattctca
     2581 agattgccat gattcagctg gataaagcct tggttgcagg tggttatcag actaagatgc
     2641 tgttacaagt gcacgatgaa atcgtccttg aagtgcctaa atctgaattg gtagagatga
     2701 aaaaattggt gaaacaaacc atggaagaag ccattcaact cagtgttcct cttatcgcag
     2761 atgagaatga aggggcaacc tggtacgagg ctaaataaaa agggggctag tcctcctttt
     2821 ttgtagtaga attctgcaaa ccttttcaaa atatgctata ctgatgaaaa aggaggattt
     2881 ctatgagtca agaatttatc aatccaagtg atggcgtgat tcgtcggtat ctcgcaacga
     2941 gtaaaaccct tgctgtggtg ggtttgtctg accgtgaaga aacaaccagc aatcgagtga
     3001 caaaggaaat gcaggctcgg ggctataaaa tcatcccagt caatcccaag gcggcaggtg
     3061 gcgaaatctt gggtgaaaag gcttatgcta gcctcgctga aattcctttt cctgtagata
     3121 ttgtcaatgt ttatcgtcgc agtgaatttc tgctcgatgt ggcgcgtgat tttctcaagg
     3181 ctgatgccaa gattttttgg gcgcagctgg gacttgaaag tctagaggcg gaagaaatct
     3241 tgcgtgctgg tggatgcgat gacatcgtga tgaatcgttg catcaagaga gaacatacac
     3301 gcttgattgg ggaagcataa gaaaaaggta gctgatgggc taccttttgt gttatactaa
     3361 atgaaaatca aagagcaaac taggaaacta gctgcgggtt gctcaaaaca ctgttttgag
     3421 gttgtagata cgactgacga agtcagctca aaacaccgtt ttgaggttgc agatagaact
     3481 gacgaagtca gctcaaaaca ccgttttgag gttgcagata gaactgacga agtcagctca
     3541 aaacaccgtt ttgaggttgc agatagaact gacgaagtca gtaacatata cctacggcaa
     3601 ggcgacgttg acgtggtttg aagagatttt cgaagagtat tagaaaatgc cgataagggt
     3661 ctgcatacca aggctggtga ggatgatggc aatccagcag acggctccga gaacaatgga
     3721 ttttccactg gatttgacca tagcgaccag attagttttg agaccgatgg cactcatggc
     3781 catgataatg aggaatttag agagttgttt gagaggggta aagaaactac tagacacacc
     3841 gagagaggtc agaagggtgg ttaggagcga tgcaaggatg aagtaaagga taaaaagtgg
     3901 gaagactttt ttcagttgta agccttgctt atttttttgc tcgcgacttt gccagtagga
     3961 gagaaagaga gtgatgggga tgatagctag ggtgcgcgtg agtttgacaa tggttgcgga
     4021 ttcgagggta ttggtctggt agagactgtc ccaagcgcta gctgtggcgg ttacagagga
     4081 agtatcattg accgcagttc ctgcaaagag ggcgaagccg tcattggata gatgaagcca
     4141 ggtgccgagg gttggaaaga tgagcgcagc caagacattg aagaaaaaga taacggagat
     4201 ggcttgggct acttcctttt ccttagcatg gataacaggc gctgtcgctg caatggcaga
     4261 acccccacag atagaagaac ctactccaat caaggtagcc agttttgtat ccagggcaaa
     4321 gaagcgctgg aagaggtagg caacaatcaa ggctattgaa atggtggaaa ggatgacagg
     4381 gagtgaagat tgcccaactg cgaagacttg agagatattg agaccaaaac caagtaagat
     4441 aacggcatac tggagcaatt tcttggaact aaaggtcaat ccaacatcca gttgtttata
     4501 agacgagaga aagggatgta ggagcattcc cataaaaatc gcaaaaacgg gtgcgccaat
     4561 aacagggaag aatcctccta agtaccaaga taggatggaa atgagaaggc agaccaagat
     4621 gcctgctcca ttttttgata gaaatgacat aaaaacctcc aaatagaatc tgttaccatt
     4681 atagacctgt aaagaggaaa agtaaaatag aaagtggaaa gctattctct aatgtatttt
     4741 tgcggtcggg gggcttttgt agtataatag agatacgttt tgaaagtagg aggtatctat
     4801 ggacttaact aagcgcttta ataaacagtt agataaaatt caagtttcgt tgattcgtca
     4861 gtttgaccag gctatttcgg agattcctgg ggtcttgcgt ttgaccttgg gggaacctga
     4921 ttttacaacg ccagaccatg tcaaggaggc ggccaagcga gcgattgatc agaaccaatc
     4981 ctactataca gggatgagtg gtctgctgac tctacgtcag gcagctagtg actttgttaa
     5041 ggaaaagtac caactggact atgctcctga aaatgaaatc ttggttacaa ttggggcgac
     5101 agaggcttta tctgcgactt tgacggctat tttggaagag ggagacaagg tacttttgcc
     5161 agctcctgct tatccaggct atgaaccgat tgttaactta gttggggcag aaattgttga
     5221 gattgatacg actgaaaatg gttttgtctt gactcctgag atgttggaga aggccatttt
     5281 ggagcagggt gataagctca aggcggttat tctcaactat ccagccaatc cgacaggaat
     5341 tacctacagt cgagagcagt tagaggcctt ggcagctgtt ttacgcaagt acgaaatttt
     5401 tgttgtctgt gatgaggttt actcagaatt gacctacaca ggcgaagccc atgtgtctct
     5461 aggaacgatg ttgagagacc aggctattat tatcaatggt ttgtctaaat cgcatgccat
     5521 gacaggttgg cgtttggggc tgattttcgc tcctgcggcc ttcacagccc agttaatcaa
     5581 gagtcaccaa tacttggtca ctgccgcaaa taccatggcg caacatgctg cggtagaagc
     5641 cttgacggct ggtaaaaatg atgcggagcc catgaagaag gaatatatcc agcgtcggga
     5701 ctatatcatc gaaaaaatga ctgctcttgg ttttgagatt atcaaaccag acggtgcctt
     5761 ctatattttt gctaaaattc cagcgggcta caatcaagac tcctttgctt ttctgaagga
     5821 ttttgctcag aagaaggccg ttgcctttat ccctggtgca gcctttggac gttacgggga
     5881 aggctacgtc cgcctatctt atgcagccag catggagact atcaaagaag ccatgaaacg
     5941 acttgaggag tacatgagag aagcatgatt cagtctatca cgagtcaagg cttggtgctt
     6001 tacaatcgca attttcgtga ggatgacaag ctcgtcaaaa tttttacaga gcaggttggc
     6061 aaacgcatgt tttttgtcaa acacgctggt cagtctaagc tggcgcctgt tattcagccc
     6121 ttggtgctgg cacgatttct cttgcgaatc aatgatgacg gactcagtta catcgaagac
     6181 tatcatgagg tcatgacttt tcccaagatt aatagtgacc tctttgtcat ggcctatgcg
     6241 acctatgtgg cagctcttgc agatgctagt ttgcaggaca atcagcagga tgctcccttg
     6301 tttgcttttt tgcaaaagac tttggagttg atggaagcag gcttggatta tcaggttttg
     6361 accaatattt ttgaaattca aattttgact cgatttggaa tcagcctcaa ttttaatgag
     6421 tgtgtcttct gccatcgggt tggtcaggct tttgactttt ctttcaaata tggagcctgc
     6481 ctctgtccag agcattatca tgaggataag agacgttgtc atctcaatcc caatatcccc
     6541 tatctgctca atcaatttca agctattgat tttgagactt tggagaccat ttcgctcaag
     6601 cctggaatca agcaagagct acgccaattt atggatcaat tatatgaaga gtacgttggg
     6661 attcacctaa aatcaaagaa atttattgat tccctagcag actggggaca attactaaaa
     6721 gaggaaaaga aatgaaaaaa atcgcagtag atgccatggg gggcgattac gcacctcagg
     6781 ccattgttga gggtgtcaat caagccctat ctgacttttc agatatcgag gttcgacttt
     6841 acggagatga agctaaaatc aagcaatatc tgacagcgac agagcgcgtc agcattatcc
     6901 atacggatga gaagattgat tcggatgatg aacctacgag agctattagg aataagaaaa
     6961 atgccagtat ggtattggca gccaaggctg tcaaagatgg tgaagcagac gctgtccttt
     7021 cggctgggaa tacaggtgcc ttgttggcag caggattctt catcgtgggt cgtatcaaga
     7081 atatcgaccg tcctggactc atgtctacct ttcctaccgt tgatggaaaa ggttttgaca
     7141 tgctagacct tggtgccaat gcagaaaata cagcccagca cctccatcaa tatgcggttc
     7201 taggttcctt ctatgctaaa aatgtccgtg gcattgcgca accacgcgtt ggtttgctca
     7261 acaacggaac agagagtagc aagggcgacc cgcttcgtaa ggaaacttat gaattactgg
     7321 cggctgatga aagtttgaac tttatcggaa acgtggaagc gcgtgatttg atgaatggcg
     7381 ttgcagatgt tgttgtggca gatggtttca cgggaaacgc tgtgctcaaa tccatcgaag
     7441 ggacagctat gggaatcatg ggcttgctca agacagctat tacaggtggt ggtcttcgag
     7501 cgaaactagg tgccctcctt ctcaaggaca gcctcagtgg tttgaaaaaa cagctcaatt
     7561 attcagatgt tggtggagcg gtcttgtttg gtgttaaggc acctgttgtc aagactcatg
     7621 gctcaagcga tgccaaggct gtttatagta cgattcgtca gatccgtacc atgctagaaa
     7681 cagacgtggt tgcccagact gcgcgtgaat tttcaggaga ataaaagaga tgacagaaaa
     7741 agaaattttt gaccgtattg tgaccattat ccaagagcga cagggagagg actttgtcgt
     7801 gacagaatcc ttgagtctga aagacgattt ggatgcggat tctgttgact tgatggagtt
     7861 tatcttgact ctggaagatg aatttagtat cgaaatcagc gatgaagaaa ttgaccaact
     7921 ccaaaacgta ggagatgtgg ttaaaatcat tcaaggaaaa tagcaatcgg agttccaagt
     7981 caacggaagt agatggtttt tagaaatgag aaatatcgga caagctggta aaatcttggc
     8041 tgacagtggt tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc
     8101 cagcaaactc aagccgctaa cagttgaaga taaagcctgt aatcatgcgc tatctaagga
     8161 gagaagcaag gttgagaata tctttgccaa agtaaaaacg tttaaaatgt tttcaacaac
     8221 ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgattgctg gtattatcaa
     8281 tcatgaacta ggattctagt tttgcaggaa gtctaatagt aaaaaagtga ttagaaaaca
     8341 tcttttttaa aaatagagat gattttgaaa caaaaaagct aattcaagac gtttcgatgc
     8401 caattcaaga tttggatgaa aaaaattaat agatactgtt atactaaact tgtcaagttt
     8461 gtaacaagac aaatattaaa aataaaaaag aggtattcgt tatgaataca aaaaagatgt
     8521 cacaatttga aattatggat actgagatgc ttgcttgcgt tgaaggtggc ggatgcaatt
     8581 ggggagattt tgccaaagca ggtgttggag gaggagctat acttggaggt gtggcctatg
     8641 cagcgacatg ttggtggtaa ttatggattt taaaagtttt attattggtt tagtagttgg
     8701 tatatttggt ccttatatgg atgatttaat tagaaaaaaa tttttaaagt cttcggagaa
     8761 gaaaacagaa aaatctgtta aaaaataatc aaaactataa atgatgaatc tgaatcaaaa
     8821 ttattttgcg catgtaaaga ggagtcttgc agtaacgaat caaaaaaaag gagtaactat
     8881 gaatcgtaat ttagaatggt gttatctatt atgactataa atagatcata ccagaggtgg
     8941 cttagaaata gcagggacat tagaaattga agtaacttta aataggatgt cgtaaatgtt
     9001 gctatcaatg atttatttgt cccaagcttg cctagggtgt cagtaaaaaa tcattttcct
     9061 ttcataccat atttttagta ggtagaacgt ttgttctgcc tattttttta tccaaaaagt
     9121 gcagttggga gggagatagg ctcatttggg aaggaagtcc agtttttgtt tagtgattgg
     9181 ggtaagatag ttgttatcag atgagtttat actcttcgaa aatcaaattc aaaccacgtc
     9241 aacgtcgcct tgccgtatat atgtgactga cttcgtcagt cctatctaca acctcaaaac
     9301 agtgttttga gcagcctgcg gctagtttcc tagtttgctc tttgattttc attgagtatt
     9361 agggaaaagg agatgaatat gaaatttggg aaacgtcact atcgtccgca agtggatcag
     9421 atggactgcg gtgtagcttc attagccatg gtttttggct actatggtag ttattatttt
     9481 ttggctcact tgcgagaatt ggctaagacg accatggatg ggacgacggc tttgggcttg
     9541 gtcaaggtgg cagaggagat tggctttgag acacgagcta tcaaggcgga tatgacgctt
     9601 tttgatttgc ccgatttgac ttttcctttt gttgcccatg tgcttaagga agggaaattg
     9661 ctccactact atgtggtgac tgggcaggat aaggacagca ttcatattgc cgatccagat
     9721 cctggggtga aattgaccaa actgccacgt gagcgttttg aggaagaatg gacaggagtg
     9781 actctgttta tggcacctag tccagactac aagcctcata aggatcaaaa gaatggtctg
     9841 ctctctttta tccctatatt agtgaagcag cgtggcttga ttgccaatat cgttttggca
     9901 acactcttgg taaccttgat taacattgtg ggttcttatt atctgcagtc tatcattgat
     9961 acctatgtgc cagatcagat gcgttcgacg ttggggatta tttctattgg gctagtcatc
    10021 gtctacatcc tccagcaaat cttgtcttac gctcaggagt atctcttgct tgttttgggg
    10081 caacgcttgt cgattgacgt gattttgtcc tatatcaagc atgtttttca cctccctatg
    10141 tccttctttg cgacacgcag gacaggggag atcgtgtctc gttttacaga tgctaacagt
    10201 atcatcgatg cgctggcttc gaccatcctt tcgattttcc tagatgtgtc aacggttgtc
    10261 attatttccc ttgttttatt ttcacaaaat accaatctct ttttcatgac tttattggcg
    10321 cttcctatct acacagtgat tatctttgcc tttatgaagc catttgaaaa gatgaatcgg
    10381 gacaccatgg aagccaatgc ggctctgtct tcttctatca ttgaggacat caatggtatt
    10441 gagactatca agtccttgac cagtgaaagt cagcgttacc aaaaaattga caaggaattt
    10501 gtggattatc tgaagaaatc ctttacctat agtcgagcag agagtcagca aaaggctctg
    10561 aaaaaggttg cccatctctt gcttaatgtc ggcattctct ggatgggggc tgttctggtc
    10621 atggatggca agatgagttt ggggcagttg attacctata ataccttgct ggtttacttt
    10681 accaatcctt tggaaaatat catcaatctg caaaccaagc ttcagacagc gcaggttgcc
    10741 aataaccgtc taaatgaagt gtatctagta gcttctgagt ttgaggagaa gaaaacagtt
    10801 gaggatttga gcttgatgaa gggagagatg actttcaagc aggttcatta caagtatggc
    10861 tatggtcgag acgtcttgtc ggatatcaat ttaaccgttc cccaagggtc taaggtggct
    10921 tttgtgggga tttcagggtc aggtaagacg actttggcca agatgatggt taatttttac
    10981 gacccaagtc aaggggagat tagtctgggt ggtgtcaatc tcaatcagat tgataaaaaa
    11041 gccctgcgcc agtacatcaa ctatctgcct caacagccct atgtctttaa cggaacgatt
    11101 ttggagaatc ttcttttggg agccaaggag gggacgacac aggaagatat cttacgggcg
    11161 gtcgaattgg cagagattcg agaggatatc gagcgcatgc cactgaatta tcagacagaa
    11221 ttgacttcgg atggggcagg gatttcaggt ggtcaacgtc agagaatcgc tttggcgcgt
    11281 gctctcttga cagatgcgcc ggtcttgatt ttggatgagg cgactagcag tttggatatt
    11341 ttgacagaga agcggattgt cgataatctc atggctttgg acaagacctt gattttcatt
    11401 gctcaccgct tgactattgc tgagcggaca gagaaggtag ttgtcttgga tcagggcaag
    11461 attgtcgaag aaggaaagca tgctgatttg cttgcacagg gtggctttta cgcccatttg
    11521 gtcaatagct agaaagagga gaggatgaaa ccagaatttt tagaaagtgc ggagttttat
    11581 aatcgtcgtt accataattt ttccagtagt gtgattgtac ccatggccct tctgctcgtg
    11641 tttttacttg gctttgcaac tgttgcagaa aaggagatga gtttgtccac tagagctact
    11701 gtcgaaccta gtcgtatcct tgcaaatatc cagtcaacta gcaacaatcg tattcttgtc
    11761 aatcatttgg aagaaaataa gctggttaag aagggggatc ttttggttca ataccaagaa
    11821 ggggcagagg gtgtccaagc ggagtcctat gccagtcagt tggacatgct aaaggatcaa
    11881 aaaaagcaat tggagtatct gcaaaagagc ctgcaagaag gggagaacca ctttccagag
    11941 gaggataagt ttggctacca agccaccttt cgcgactaca tcagtcaagc aggcagtctt
    12001 agggctagta catcgcaaca aaatgagacc atcgcgtccc agaatgcagc agctagccaa
    12061 acccaagccg aaatcggcaa cctcatcagt caaacagagg ctaaaattcg cgattaccag
    12121 acagttaagt cagctattga aacaggtgct tccttggccg gtcagaatct agcctactct
    12181 ctttaccagt cctacaagtc tcagggcgag gaaaatcccc aaactaaggt tcaggcagtt
    12241 gcacaggttg aagcacagat ttctcagtta gaatctagtc ttgctactta ccgtgtccag
    12301 tatgcaggtt caggtaccca gcaagcctat gcgtcagggt taagcagtca attggaatcc
    12361 cttaaatccc aacacttggc aaaggttggt caggaattga cccttctagc ccagaaaatc
    12421 ttggaggcag agtcaggtaa gaaggtacag ggaaatcttt tagacaaggg gaaaattacg
    12481 gcaagtgagg atggggtgct tcatcttaat cctgagacca gtgattctag catggttgca
    12541 gaaggtgccc tactagccca actttatcca tctttggaaa gagaagggaa agccaaactc
    12601 acagcctatc taagttcaaa agatgtagca agaatcaagg tcggtgattc tgttcgctat
    12661 actacgactc atgatgccgg gaatcaactt tttctagatt ctactattac aagtattgat
    12721 gcgacagcta ctaagactga gaaagggaat ttctttaaaa tcgaggcgga gattaatcta
    12781 acttcggagc aggctgaaaa acttaggtac ggggtggaag gccgtctaca gatgattacg
    12841 ggcaagaaaa gttatctacg ttattatttg gatcaatttt tgaacaaaga gtaatgttcg
    12901 tgtttttaga gttaaataat ttttaaactg tgagaaagat tcttcttgca gttttttctt
    12961 tacaattttt gaaaaacatc tgctatttat tcggttaaat tcttgtgttt tttggttttt
    13021 tgtggtaaaa tgtgctcaag taatacgaaa ggcgaacttt aaaatgtcaa aacaattgat
    13081 ctattcggga aaagctaaag atatctatac aactgaggat gaaaatctta ttatttcaac
    13141 ttacaaggac caggcgactg ctttcaacgg tgtcaagaag gagcagattg caggtaaggg
    13201 agtcttgaat aatcagatct catcttttat ttttgagaaa ttaaatgcgg ctggtgtggc
    13261 gactcacttt gtggagaaac tttcagacac ggaacaactc aataaaaagg ttaagattat
    13321 tcctttggaa gtcgtgctcc gcaactatac tgctggttcc ttttcaaaac gttttggtgt
    13381 ggatgaggga atcgccttgg agactccgat tgtcgaattt tactacaaaa atgatgattt
    13441 ggatgatcca tttatcaatg atgagcatgt gaaattccta cagattgcgg atgaccagca
    13501 gattgcctac ttgaaggaag aaacgcgtcg tatcaatgaa ctattgaaag tctggtttgc
    13561 tgagattggg cttaaattga ttgactttaa gctagagttc ggttttgaca aggatggcaa
    13621 gattatcttg gcagacgaat tttcaccaga taactgccgc ttgtgggatg ctgatggcaa
    13681 ccacatggat aaggatgttt tccgtagagg attgggagaa ctaaccgacg tttatgagat
    13741 tgtttgggaa aagttgcagg aattgaaata atctgtttgc aatggaaaac cttcgtctct
    13801 caactaaaag gactcaggct gaaaaggtcc cccagacctt ttcactctgt agagaactag
    13861 gtgaaccaac cgatgtttac gaaattgtct gggaaaagtt gcagggttta aaataacaac
    13921 ctcaaggctg tttgggaata ttgcaagagc tgaaataaag gaataagaat tgatggataa
    13981 acgtattttt gttgaaaaaa aggctgattt tcaggtcaag tcagagagtt tggttagaga
    14041 gctccagcac aacttgggac tgtcaagctt gaaaagtatt cgtattgtgc aagtatatga
    14101 tgtatttgac ttggctgagg acttgtttgc acctgcagag aagcacattt tctctgagca
    14161 ggtaaccgac catgttttag atgaagtatc tgtgcaggcg gatcttgcta actatgcttt
    14221 ctttgccatt gaaagtctgc cagggcagtt tgaccagcgt gcagcttcgt cacaggaagc
    14281 cttgcttttg ttgggaagtt cgagtgacgt gacagtcaac acagcccaac tttacttggt
    14341 gaataaagat attgatgcga ctgagttgga agctgtcaaa aactacctgc tcaatccagt
    14401 tgattctcgt ttcaaggata tcacgacagg gattgccaag caggagtttt cagagtcaga
    14461 caagaccatt ccaaaattga ctttctttga aagctataca gcagaagact ttgctcgcta
    14521 caaggccgaa caagggatgg ccatggaagt ggatgatttg ctctttatcc aagactactt
    14581 taagtcaatc gggcgcgtgc caactgagac tgaacttaag gttttggaca cttactggtc
    14641 tgaccactgc cgtcatacga cttttgagac agagttgaaa cacatcgact tttcagcttc
    14701 taaatttcaa aagcaattgc agtcaaccta tgacaagtat attgccatgc gcgaggaatt
    14761 aggtcggtct gaaaaaccac aaaccttgat ggatatggcg actattttcg gtcgttatga
    14821 gcgtgctaat ggacgattgg atgatatgga agtctctgac gaaatcaatg cctgctcagt
    14881 tgaaattgaa gtggacgttg atggtgtcaa ggaaccttgg ctcctcatgt ttaaaaacga
    14941 aacccacaac catccaacag aaattgagcc atttggtgga gcggctacct gtattggtgg
    15001 agctattcgt gatccgttgt caggccgttc ctatgtttac caagccatgc gtatttcagg
    15061 tgctggtgat attacagcac cgatttcgga aactcgcgct gggaaattgc cacaacaagt
    15121 catttctaaa acagcagctc atggttattc ttcatatggt aaccagattg ggcttgcaac
    15181 aacctacgtt cgtgaatact tccacccagg ctttgtagct aaacgtatgg aacttggtgc
    15241 cgttgttggt gcggctccca agggcaatgt tgtccgtgaa aaacctgaag caggtgatgt
    15301 gatcatcctt ctcggaggca aaacaggtcg tgatggtgtc ggtggtgcga cgggctcttc
    15361 taaggttcaa acagttgagt ctgtagagac tgctggtgct gaggttcaaa aaggaaatgc
    15421 catcgaagaa cgcaagattc agcgcctctt ccgtaatggc aatgtcactc gtctgatcaa
    15481 gaagtccaat gactttgggg caggcggtgt ctgtgtggct atcggtgaat tggcagacgg
    15541 tcttgaaatc gacctcaaca aggtgcctct taaataccag ggcttgaatg gtacagaaat
    15601 tgccatctct gaatcacaag aacggatggc ggtcgtggtt cgtcctgaag atgtggatac
    15661 cttcgttgcc gaatgtaaca aagaaaatat tgatgctgtt gtggtggcga cagtaactga
    15721 aaaaccaaat cttgtcatgc actggaatgg tgagacaatc gttgacttgg agcgtcgttt
    15781 ccttgacacc aatggtgtgc gcgtggttgt cgatgccaaa gttgtggaca aggatgtcaa
    15841 actcccagaa gagcgtcaaa catctgctga aacactggaa tcagataccc ttacggttct
    15901 atctgacctc aaccatgcaa gtcaaaaagg attacagact atctttgact gctctgttgg
    15961 acgctcaacg gttaatcacc cacttggtgg tcgttaccaa ctcacaccaa ctgaggcatc
    16021 tgtgcagaaa ttgccagttc aacacggtgt gactcatact gcgtcggtca ttgctcaagg
    16081 tttcaaccca tatgtagctg aatggtctcc ataccacggt gctgcttatg cggttatcga
    16141 agcaactgct cgtttggtgg ctgctggtgc caactggtcc aaggctcgtt tctcttacca
    16201 agagtatttc gagcggatgg acaaacaagc agagcgtttc ggtcagccag tagccgccct
    16261 tctaggttct attgaagcac aaattcagct tggcttgcca tctatcggtg gtaaggactc
    16321 catgtctggt acctttgaag aattgaccgt tccgccaacc ttggctgcct ttggggtgac
    16381 gacggcagat agccgtaagg tgctctctcc agaatttaaa gctgttgggg aaaatatcta
    16441 ctacatccca ggtcaagccc tctctgcaga gattgatttt gacttgatta agaaaaattt
    16501 tactcagttt gaagccatcc aagctgacca taaagtgaca tctgcatcag ctgtcaaata
    16561 cggtggtgta gttgaaagtt tggctcttgc tacctttgga aactatattg gtgcagaggt
    16621 gaccttgcct gaacttaaaa cagctttgac agctcaatta ggcggctttg tcttcacatc
    16681 tcctgaagaa attgctggag tagagaaggt tggacaaacg aaagcagact ttacactgac
    16741 tgtcaaccgt gtgaaactag atggacacaa gcttgacagt gcatttcaag ggacattgga
    16801 agaagtttac ccaacagaat ttacccgagc gaaagaacta gaagaagtac cagctgtggc
    16861 atcagatgtt gtgattaaag ccaaagaaaa ggttgaaaaa cctgtggttt acatcccagt
    16921 ctttccagga accaactcag aatatgattc agctaaggcc ttcgaaaaag aaggtgcaga
    16981 ggtcaatttg gtgccattcg tgaccttgaa tgaagaagct attgtcaagt cagttgaaac
    17041 tatggttgac aatatcgaca agactaatat tctcttcttt gctggtggat tctcggctgc
    17101 ggatgaacca gatggttcag ctaagtttat cgtcaatatc ctgcttaatg aaaaagtgcg
    17161 tgtggctatt gatagcttta tcgcccgtgg tggtttgatt atcggtattt gtaatggatt
    17221 ccaagcctta gtcaaatcgg gtctcctacc ctacggaaac tttgaagctg ctaacagtac
    17281 tagcccaacc ctcttctaca atgatgccaa ccaacacgtg gccaagatgg tggaaactcg
    17341 tattgccaat accaactcac catggttggc tggtgtgcaa gtgggcgata tccacgctat
    17401 tcctgtttcg cacggtgaag ggaagtttgt cgtgacggct gaggaatttg cagagctccg
    17461 tgacaatgga caaattttca gccaatacgt tgactttaac ggtaaaccaa gtatggattc
    17521 taagtacaat ccgaatggtt ctgtccatgc catcgaagga attaccagca agaatggtca
    17581 aatcatcggt aagatgggcc actcagaacg ttatgaggat ggtcttttcc aaaatatccc
    17641 aggcaataaa gaccaacacc tgttcgcatc agcggttaaa catttcactg gaaaataaga
    17701 cttacagatt ttctaataga tagtatcagt aatgtaaaag tcatgtaaat ctagctcttg
    17761 atgattacaa atgaaaatta ggtataaaaa atgacatacg aagtaaaatc tcttaatgaa
    17821 gaatgtggtg ttttcggtat ttggggacat ccagatgctg ctaagttgac ctattttgga
    17881 ctccacagtc ttcaacaccg tggtcaggag ggggcaggaa tcctctccaa tgatcaagga
    17941 caactgaagc gccatcgtga catggggctt ttatcagaag ttttcagaaa tccagccaat
    18001 ttggataaat tgacaggagc tggtgcgatt gggcatgtgc gttatgcgac tgctggcgaa
    18061 gcttctgttg ataacatcca acccttcctc ttccgttttc acgatatgca gtttggtttg
    18121 gctcataatg gaaatctgac caatgcagcc tctctcaaga aagaactgga acaaagagga
    18181 gcaattttca gcgcgacttc ggactctgaa atcttggctc acctcattcg tcgcagtcat
    18241 aatcctagcc tgatgggcaa aatcaaggaa gcgctcagtc ttgtcaaagg tggttttgcc
    18301 tatatcttgc tgtttgagga caagttgatt gcggctcttg accctaatgg ctttcgtccg
    18361 ctttctatcg ggaaaatggc caacggagcg gtggttgttt cctctgaaac ctgtgctttt
    18421 gaggtcattg gtgccgagtg gatttgtgat ttgaagccag gtgagattgt gatcattgat
    18481 gacgagggca ttcagtatga cagctataca gatgataccc agttggcgat ttgttctatg
    18541 gagtatatct actttgcccg ccctgattct aatatccacg gtgtcaatgt ccatacggca
    18601 cgtaagagaa tgggagcgca attggcgcga gaatttaagc atgaggcaga tattgtagtt
    18661 ggtgtgccca attcttccct aagcgcggct atgggatttg cggaagaatc aggcttacca
    18721 aatgaaatgg gtctgatcaa aaaccaatac acccagcgaa cttttatcca accgactcaa
    18781 gaattgcggg agcaaggagt gcggatgaaa ctgtctgctg tttcgggtgt tgtcaaaggc
    18841 aaacgtgtgg tcatggtgga tgattccatt gtacgtggaa caacctctcg tcgtatcgtt
    18901 cagctcttga aagaagcggg tgcgactgag gttcacgttg ccattggaag tcctgcacta
    18961 gcgtatccat gtttctacgg gattgatatc cagacccgtc aggagctgat tgcagccaat
    19021 catacggtcg aagaaactcg ccaaatcatt ggtgcggaca gtctgactta tctttcaatt
    19081 gatggcttga ttgagtcgat tggtatcgaa acagatgcgc cgaacggtgg tctctgtgtc
    19141 gcttactttg acggtgacta cccaacgcct ctctatgact acgaagaaga ctatcgtaga
    19201 agtttggaag aaaagaccag tttttacaag taggcgacag attctccatt aaagaaaagg
    19261 aaaaaacaaa tgacaaataa aaatgcatat gcccagtcgg gtgtggatgt tgaagcgggt
    19321 tatgaagttg ttgaacggat taaaaagcac gtggcccgta cggagcgtgc aggtgtcatg
    19381 ggagctcttg gtggctttgg tggtatgttt gacctttcca agactggggt taaagaaccc
    19441 gtcttgattt cagggactga cggtgtcgga accaagctca tgttggctat caagtacgac
    19501 aagcacgata ccatcgggca ggactgtgtg gccatgtgtg tcaacgacat cattgctgca
    19561 ggtgcggaac ccctctattt tctcgactac gtagcgacag ggaagaatga accagctaag
    19621 ctagaacaag tggttgctgg tgtggcagaa ggttgtgtgc aggctggtgc tgccctcatc
    19681 ggtggggaaa cggctgaaat gccgggcatg tacggcgaag acgactatga cttggctggt
    19741 tttgcggtcg gtgtggctga aaaatctcaa atcattgacg gttcaaaggt ggtagaggga
    19801 gatgttcttc tcggacttgc ttcaagtggg attcactcaa atggttactc tttggttcgt
    19861 cgtgtctttg cggattacac aggtgaggaa gtcctaccag aattggaagg caagaaactt
    19921 aaggaagttc tacttgagcc gactcgtatc tatgtcaagg ctgtcttgcc gctcatcaaa
    19981 gaagagttgg tcaacggcat tgcccacatc acaggtggtg gctttatcga aaatgtccct
    20041 cgtatgtttg cagatgacct agctgctgaa attgatgaaa gcaaagttcc agtgcttcca
    20101 attttcaaag cccttgaaaa atatggtcag attaaacacg aagaaatgtt tgaaatcttc
    20161 aatatgggtg tgggacttat gttggcggtc agccctgaaa atgtagagcg tgtaaaagaa
    20221 ttgttggatg aagcagtcta tgaaattggt cgcatcgtca agaaagaaaa cgaaagtgtc
    20281 attatcaaat gaaaaaaata gcggtttttg cctctggtaa tggctcaaat tttcaggtga
    20341 ttgccgaaga atttccagtg gagtttgtct tttcagacca tcgtgatgcc tatgtgcttg
    20401 agcgtgcaaa gcagctcggc gttctgtcct atgcttttga actcaaggag tttgagagca
    20461 aggcagacta cgaagcagcc cttgtcgaac tcttggaaga acaccagatt gacttggttt
    20521 gcctagcagg ctacatgaaa atcgttggac caaccttatt gtcggcttat gaaggtcgga
    20581 ttgtcaacat tcatccagcc tacttgccag aatttccagg agctcatggg attgaggatg
    20641 cttggaatgc tggcgtgggt cagtctggtg tgaccattca ctgggtggat tcgggtgtgg
    20701 atacaggcca ggtcatcaaa caggttcgtg tgccacgact agctgatgat accattgaca
    20761 gatttgaagc tcgcatccat gaagcagagt acaggttgta tccggaagta gtgaaggctc
    20821 tatttacaga ttgacttttt gatgattcat atgatatctt tgattttaaa ttggagtcag
    20881 tgtttgttga agacggcttc aaacggaggt atttgtaatg ttagaatcta aaaaaacaac
    20941 tcgatatgta ttttatgtct atctgatgtt attaacttgg ggaatcttat ttaagtttga
    21001 aacaaatcct gaatttatag catttttctt agctccaagg tatatcaatt ggattccatt
    21061 ttcagaacca ctaatagtcg atggaaaaat tgtttttgct gaaatgttat ttaatctgat
    21121 tttctttatt ccattaggtg tttgtttccc tttgataaaa actaatttat ctagtttaag
    21181 aatagtcggg acaggtttct tgattagttt attgtttgag tgcttacagt atattttagc
    21241 aataggtata acagatataa cgaatttgac tttaaatacg ctaggtgtct gtgtaggctt
    21301 actgatttat caaattttta taagagtgtt caaatcacag actagaaaat ggatcaatat
    21361 cttaggtatg cttagccttg gttttgctta tcttgtttta ctgttactgc atttaattgg
    21421 tgtttaacta atgattaaaa aggagaatat aatgactaaa cgcgtcttaa tcagcgtctc
    21481 agacaaagcg ggcattgttg aatttgccca agaactcaaa aaacttggtt gggagattat
    21541 ctcaacaggt ggaactaagg ttgcccttga taatgctggg gtggatacca ttgctatcga
    21601 tgatgtgact ggtttcccag aaatgatgga cggtcgtgtg aagaccctcc acccaaatat
    21661 ccacggaggg cttctcgctc gtcgtgactt ggatagccac ttggaagcgg ctaaggacaa
    21721 caagattgag ctcattgacc ttgtggtggt caacctttac ccatttaagg aaactatcct
    21781 taaaccagat gtgacttatg ctgatgcagt tgaaaatatc gatattggtg ggccatctat
    21841 gcttcgttca gcagcgaaaa atcatgccag tgttacagtt gtggtagatc ctgctgacta
    21901 cgctgtggtt ttggatgaat tggcagcaaa cggcgaaacc tcttatgaaa ctcgccaacg
    21961 tttagcagcc aaagtatttc gtcacacagc ggcttatgac gccttgattg cagaatactt
    22021 cacagctcaa gtgggtgaaa gcaagcctga aaaactcact ttgacttatg acctcaagca
    22081 accaatgcgt tacggtgaga atcctcaaca agacgcggac ttttaccaga aagctttgcc
    22141 tacagactac tccattgctt cagccaaaca gctcaacggg aaagaattgt catttaataa
    22201 tatccgtgat gcagatgctg ctatccgtat catccgtgac ttcaaagata gtccaaccgt
    22261 tgtggctctc aaacacatga atccatgtgg aattggtcaa gctgatgaca tcgagactgc
    22321 ttgggactac gcttatgagt ctgacccagt gtctatcttt ggtgggattg tcgtcctcaa
    22381 ccgtgaggtg gatgctgcga cagctgagaa gatgcacggc gttttcctcg aaatcatcat
    22441 tgcaccaagc tatacggatg aagcgctagc cattttgatc aataaaaaga aaaacttgcg
    22501 tatccttgcc ttgccattta atgctcaaga ggctagcgaa gtggaagcag aatacacagg
    22561 tgtagtcggt ggacttctcg tgcaaaatca agacgtggtc aaggaaagcc cagctgactg
    22621 gcaagtggtg actaaacgtc agccaactga gacagaagcg actgctcttg agttcgcttg
    22681 gaaggctatc aagtacgtca aatcaaatgg tattatcgtg accaacgacc acatgacact
    22741 tggtgttggt ccaggtcaaa ccaaccgtgt ggcttctgtt cgccttgcca ttgaccaagc
    22801 caaagatcgt ctggacgggg cggtccttgc ttcagatgcc ttcttcccat ttgcggataa
    22861 cgtggaagaa atcgccaaag caggaattaa ggccatcatc cagcccggtg gctctgtccg
    22921 tgaccaagaa tccatcgaag cagcggataa atacggcttg actatggtct ttacaggtgt
    22981 gagacatttt agacattaag aagataaaag ggaagaaaac agtttctttc cttttttggc
    23041 ttaaaatgct aactgaaaca agattaaaac gaactttttt gatataatgt tggtaaataa
    23101 ttcgcaaaag aggttgagga atgaaactgc ttgttgtcgg ttctggtggt cgtgagcatg
    23161 cgattgctaa aaagttactt gaatcaaaag acgtggaaaa agtctttgta gctcctggga
    23221 atgatgggat gactctggat ggtttggaat tggtaaatat ctctatttcc gaacattcta
    23281 aattgattga cttcgcaaag accaatgatg ttgcttggac ctttatcggt ccagatgatg
    23341 cccttgctgc tggcatcgtg gatgatttta accaagctgg acttaaggcc tttggtccga
    23401 ctagggctgc agcggagctg gagtggtcca aggatttcgc caaggaaatc atggtcaaat
    23461 acggcgttcc gacagcaata tatggcacat tttcagattt cgaggaagcc aaggcctata
    23521 tcgaaaagca tggtgcgcct atcgtagtca aggcggatgg cttggcactt gggaagggtg
    23581 tcgtcgttgc tgagacggtt gagcaagcgg tcgaagccgc tcatgagatg cttttggaca
    23641 ataaatttgg tgactcaggt gcgcgcgtgg ttattgagga attccttgaa ggagaggaat
    23701 tttcactctt tgcctttgtc aatggtgata agttctacat catgccaacg gctcaggacc
    23761 acaaacgtgc ctatgatggc gacaaagggc ctaacacggg tggtatgggt gcctatgcgc
    23821 cagttccaca cttaccacag agtgtagttg atacagcggt tgacaccatt gtcaagccag
    23881 ttctagaagg ggtgattaaa gaaggtcgtc cttatctggg agttctttac gcagggctta
    23941 tcctgacagc tgatggaccg aaggtcatcg agttcaacgc tcggttcgga gatccagaaa
    24001 ctcagcttat cttgcctcgc ttaacctctg actttgctca aaatatcaca gatatcctgg
    24061 atagcaagga gccaaatatc acgtggacgg acaagggtgt gactctgggt gtggttgtcg
    24121 catccaaggg ctacccgcta gattattcaa agggtgttga gttgccagtc aaaaccgatg
    24181 gcgacatcat tacctactat gcaggggcta agtttgcgga aaatagcaga gcactgctct
    24241 caaacggcgg acgagtttat atgctcgtta ccacagcaga taccgtcaaa gaagcccaag
    24301 ccagcatcta ccaagaacta tcccaacaaa aaatagaagg actcttctac cgaacagata
    24361 tcggaagcaa ggcaattaag taaagatata agaataacgc gccgtagtcg ccaaacacga
    24421 taatggtcgt cgtggtgaaa agaccagaac agtgaatgtt ctggtcaggg ggaaacttgg
    24481 agaccgtagg ctcaaagttt aggaatgaaa ccgaaggttt gcttccgcct ccatcaccta
    24541 agaccattat caaaaagaaa aataaaaatt cacaaaatac gttaatggtc gtatggtttg
    24601 cgagcgttag cgagctaata tagaataatc accgccgttg tgaaagaacg attggatgac
    24661 aatccaatcg ttcagggaaa ttggaagacc ttgggtttcc aatttaggca tgagacacct
    24721 ttggtggctg ctgccgtccc tcacaagcta aggtgattgt tgaaaaagag gaaaaaggag
    24781 aagaaatgaa accagtaatt tccatcatca tgggctcaaa atccgactgg gcaaccatgc
    24841 aaaaaacagc agaagtccta gaccgcttcg gtgtagccta cgaaaagaaa gttgtttccg
    24901 cacaccgtac accagacctc atgttcaaac atgcagaaga agcccgtagt cgtggcatca
    24961 agatcatcat cgcaggtgct ggtggcgcag cgcatttgcc aggcatggta gctgccaaaa
    25021 caacccttcc agtcattggt gtgccagtca agtctcgtgc tcttagtgga gtggattcac
    25081 tctattctat cgttcagatg ccgggtgggg tgcctgttgc gaccatggct atcggtgaag
    25141 ctggagcgac taacgcagct ctctttgccc tccgtctcct ctctgtagaa gataagtcca
    25201 ttgcggatgc acttgccaac tttgctgaag aacaaggaaa aatcgcagag gagtcgtcaa
    25261 atgagctcat ctaaaacaat cggaattatc ggtggcggtc aactgggtca gatgatggcc
    25321 atttctgcta tctacatggg ccacaaggtt atcgcgctgg atcctgcggc ggattgcccg
    25381 gcctctcgcg tggcggaaat cattgtggca ccttataacg atgtggacgc cctccgtcag
    25441 ttggcagacc gttgcgatgt cctcacttat gagtttgaaa atgtcgacgc tgacggtttg
    25501 gatgccgtta tcaaggatgg acaactccct caaggaacag atctgctccg catttcgcaa
    25561 aatcgtattt ttgaaaagga ctttttgtca aacaaggctc aagtcactgt ggcaccctac
    25621 aaggtcgtga cttctagcct agacttggca gatatcgact tgtcgaaaaa ctatgtcctc
    25681 aagactgcga ctggtggcta cgatggtcat ggacaaaagg ttattcgttc agaagcagac
    25741 ttggaagcag cctatgcgct agcagactca gcagactgcg tcttggaaga atttgtcaac
    25801 tttgaccttg agatttctgt catcgtgtca ggaaatggca aggaggtgac gtttttccca
    25861 gttcaggaaa atatccaccg caacaatatc ctgtctaaga ccatcgtacc agcccgcatt
    25921 tctgaaagtc tagcagacaa ggctaaagct atggcagtgc gaatcgcaga acaactcaac
    25981 ttgtctggaa ctctctgtgt ggaaatgttt gcgactgatg atgacgttat tgtcaatgaa
    26041 atcgccccac gaccacataa ctctgggcac tattctattg aaacctgtga tttctctcag
    26101 tttgacaccc atattctggg tgttctcgga gcaccattac cagtcatcaa actccatgcg
    26161 ccagccgtta tgcttaatgt cctcggtcag catgtcgagg ctgctgagca atatgtgaca
    26221 gaaaattcaa gcgcccacct ccacatgtat ggtaaaatag aagcaaagca taatcgtaag
    26281 atgggacatg tgactttgtt tagtgatgtg ccggatagtg tggaagagtt tggggaaggg
    26341 attgattttt aggacaagtc tatgatacaa attatcgtta atacatttat tgaaaaggat
    26401 aagactggag cagttgttga agtgttgtat gccagtgctg accaagataa ggtacaagct
    26461 aaatatgaag aactagctgc acaatacccc gaaaattatt tagctatcta tgatgtaccg
    26521 ctggatacgg atttgaatac actagatcat tacccgtctg tgtttattga aaaagaggag
    26581 tttgagtaga aatcttggtt tacctagata gcttattccc aacagcttaa gaagaaagga
    26641 aaaattaaca catgatcaac cgttactctc gccctgagat ggcgaatatt tggagtgaag
    26701 aaaataaata ccgtgcttgg cttgaggtgg aaatcctctc tgacgaggca tgggctgagt
    26761 tgggggaaat ccctaaggaa gatgtggctt tgattcgcaa gaaggcggac tttgacatcg
    26821 accgtatttt ggaaattgag caggagacgc gccacgatgt ggtggctttc acgcgtgcgg
    26881 tttctgagac tcttggtgaa gagcgcaagt gggttcacta tgggttaact tctaccgacg
    26941 tggtggatac tgcttatggt tacctctaca agcaggccaa cgacatcatc cgtcgtgacc
    27001 ttgaaaactt cactaatatc atcgctgaca aggccaagga gcacaagttc accatcatga
    27061 tggggcgtac tcatggtgtg cacgctgagc cgacaacctt tggtcttaaa ttggcaactt
    27121 ggtacagcga aatgaaacgc aatatcgagc gtttcgagca tgcagctgct ggtgtagaag
    27181 ctggtaagat ttctggtgcg gttgggaact ttgccaatat cccaccattt gtagaggagt
    27241 atgtctgcga taaacttggc atccgtgccc aagaaatctc tacacaagtc cttcctcgtg
    27301 accttcacgc tgagtacttt gcggttcttg ccagcattgc gacttcaatc gaacgtatgg
    27361 cgactgagat tcgtggtcta caaaaatctg agcaacgcga agtagaagag ttctttgcta
    27421 aagggcaaaa agggtcttca gcaatgcctc acaaacgcaa cccaatcggt tctgaaaata
    27481 tgactggtct ggcgcgtgtc attcgtggtc acatgattac ggcttatgaa aacgtcgctc
    27541 tctggcacga acgcgatatt tctcactcat cagctgagcg tatcatcaca ccagatacga
    27601 ccattttgat tgactacatg ctcaaccgtt ttggaaatat cgtcaagaac ttgacagtct
    27661 tcccagaaaa tatgatccga aacatgaact cgacttttgg tcttatcttt agccaacggg
    27721 ctatgttgac attgattgaa aaaggcatga cccgtgagca agcctatgac ttggtgcaac
    27781 caaaaacagc ctactcttgg gacaaccaag tagactttaa accacttctt gaggcagatt
    27841 cagaagtaac atcacgtctc actcaagaag aaatcgatga aatcttcaac ccagtttatt
    27901 acaccaaacg agtggatgat atctttgaac gtcttggact aggtgattaa ttaaaaaata
    27961 aacagcgagc ttcaatctcg ctgtttattt tttatcgaaa agacttagtc ttcttttctt
    28021 ttagtgagtc cataggctgc tagtgtggac atgagtcctg cgactactag tcctgcagaa
    28081 tcgtgagttc ctgtttcagg aagttttttc tctgttacca caggagctgg atcttgagga
    28141 agagctttgc tttcctcagc aggagcagtt gatggagctg gttggcttgg gatttctagt
    28201 tttggttttt cttcagcaat agcggcttgt ccgttttcat cgcctacatg tgttaccata
    28261 gttccgactt cgactatttg agtaacggct tcctgtgcta cgacactatt tacaagtgtt
    28321 ttcacttcct taccatcggc agaagtgctc acagagtaga agttgctacg atgtccattg
    28381 acgcccttag taatgacttg tgtttttcct ttgagtaaga gtggattttc acgagtcact
    28441 gtggtaaatg gaatttcttc tttttggata tccagtctag gttttacctc agtagttggt
    28501 gcaagaccac tttcatcacc cttgtgagtt acaggagcgc caacttcaac cacttggttt
    28561 ataacttctt tggttacctg gctatcaagg actgtttctg ttgtttttcc attttcagtg
    28621 agtacagaga tgtaatgagt tcgttcacct ttgactcctg ctgtgataat attttcttga
    28681 ccagctggga ggttaggatt ttctttcttg ataacttcaa atggaatttc ttcagttctt
    28741 gtgatgagtt ctggtctggt ttcaacattg gcagccactt cattttcatc taggcttcct
    28801 gaatgagttg cagctggttt gaggccttga agagcggctt ttaggttggc tacaagtgtg
    28861 tcaagctcag cttgtttatt acggttgagg ttgtaattta gagctgtttt agctgcgtca
    28921 agggcctcaa gactttcttt actatatcct tctaagtttg taggaatttt agctaattct
    28981 tcgcggagag cattataatt agcacggaag tagtctttgt tgtggtctgc aaaggcagtc
    29041 atgagttcaa agatttcctc ttccttgtat tcagcgcttg gtctatctgc ccagattgaa
    29101 agcatacttc cgactgttgg aagatctact tcaggatatt tggtagaagc tagttgattg
    29161 aatggaactt taccagaatt ttcaactgct tttgaaagag ggtaagcttc ctcttgtttg
    29221 tgattgccta taacataata ccagtcaccg ttggtattca agaatttata gcctttgctt
    29281 gctaggtatt gaggtgatgc gaggttatat ccccaccagc ctttagacca gtaagaaatc
    29341 aagacatctt tgtcaaactg aacatcgtcc ttgtcttcat agtagaagcc atcgttgaag
    29401 gccattggtt gaagccctct ttctttggcc atagctgcga gggtgttggc atattcggca
    29461 aatttgccat agagttgata ccacttgagg tagtaccagc cttgggcact agtcgcatcg
    29521 ttggcgtatt cgtcagtacc aaagttgaaa atctttgttt tacctgcaaa gaagtccatg
    29581 tatttaccga tgagggcttt tacaaagtcc atcgcttctt cgtttttcaa gtccatagtt
    29641 gtttttgaaa ctttatcaaa gtgggcttga ggatttttaa tacctaattt ttccatggca
    29701 accagcatag catccatgtg acctggactg ttaatagctg ggatgagacc gatgtcctta
    29761 gatttagcgt attcaattag ctctgtcact tctgcctgtg ttagtgcagt accgtttgga
    29821 tcgtcgtagt aagctttagt tccttcgata atagcttttt taacgtcatc actagcatag
    29881 gtttttccgt tggcagtaat ggtcatatca ttgagtagaa agcgaagtcc gtcatttcct
    29941 agaaggagat ggacatcaga atatccgagc tcactggcct tgtctacgat gcgtttgagc
    30001 tggttcagag taaagtattt gcgtccagca tcgattgaga ttaccttgtt tttggcaagt
    30061 ttttcaacct cacgtttagc ttcttcttct ttttgagctt caggcgtgag ggtcaagttg
    30121 ttgacagttt cttgaagttt agcaatggct tgatcaatcg tatcttgttg ggcacggcta
    30181 aggttgctat cgagagagcg aatagctttt tcagcttctt ttacggccgc gacgctttct
    30241 gcagtataac ggttcaggtc ttttggtacc tcgttaagtg cttgctctgc agattcataa
    30301 tcagctgcga agtattcagc gttggcattt gcaaaatgac gcatgagttt gaagaggcgt
    30361 gatggtgaat aacgtgcaga tggagtgtca gcccaagcag ctaccatacc accgatgatt
    30421 gggatatcag ctccttctgt ttttggtaca gaagtgattg gtgtgttttt aataccattg
    30481 agcccctgat cgagattgta ccagccttgg ccatcagcgt ttcgtccaag aacgtagtac
    30541 caagcatcat tggtattaag gatttggtga cctttttcag ctagtagttt agaagaagcg
    30601 acatcgtagc ctccccaacc accagtccac atagaaacga tgatgtcttt gtcaaaacta
    30661 ccaaagcttg tgtcgctatt gtagtagata ccgtcgttaa aggccattgg tttgagaccg
    30721 tgcgatttta caatacgagc gaggtcattg gcgtaggcaa taaatttttc atagcctttt
    30781 acagggtagc cttcgtttgg atagtattta tcagcttgaa gcacactcca acctttagca
    30841 tctgtcgcat cattggcata ttcatcaagt ccgatgttga agatttcagt ctttttcgcg
    30901 aaataagcag catacttgtc gataagggct tttgtaaaag cgacagcttg ttcgttgtca
    30961 agatcgacag tacgggctga tttcttccca aaatagctaa agttagggtt ttggattccc
    31021 aattctttca tggcattgag aatcgcatcc atgtgtccag gactatttac tgtcggaatg
    31081 agaccgatac ctttatcttt ggcatagtta atcagatctg tcatttgact ttctgttaag
    31141 tgattgccgt ttggatcgtt gtaataatca tttgtacctt tttcaatggc gcgtttgaca
    31201 tcgtcactgg cataggtctt gccgttagct gtgatgctca tatcgtccaa catgaaacgg
    31261 agtccatcat ttccgactaa taggtgtaaa tcagtgtagc cataatgttt cgctttatcg
    31321 atgatttcct tgagctgttc tggtgagaaa tatttacgtc cagcatcaat agaaacaatt
    31381 ttctttttcg ctagtttttc atttacagtt gcagcacgtt cctttcctgc ctctgtttcc
    31441 ggtttgtcag cctctgcttt cgcttcatct tttttagctg gtttatcctt gtcagtcttg
    31501 tctgtatttg actctttaga atcaacctct ttcgcttctt cctttttagg gctagcttct
    31561 tctgcctttt tattagcagt ttctttttca gcagaagttg gagttaccac ctctgcttta
    31621 tcactaggag ttgaactaac ttcctcttgt ggtttttctt ctgtttttgg aagactagct
    31681 accttatcag tagctggagt ttctgtttct acagtttttg gagcttctgg ttgaagctct
    31741 gctttaggtg tttcctcagt ccgattttcg gatgattgag gggaatcaga aactgtatgg
    31801 atggtcggtt ggttttctgt agtagtagta gtaactccat cggctgcaac agtctgtgct
    31861 tggaaggcaa atccaattag aacagaagct gctcctacag cgtatttacg aatagaaaaa
    31921 cgctgttgtt tttcatgttt cattgcaaaa cctcctgatt gcattgttat attgatagcg
    31981 attatataaa tcaacgccct tattttattt cttatattaa cgagagtcaa gaggagatga
    32041 caaaaaacta taataagtat aaaaaaatat aaaatttaaa cttaagattt cagattggtc
    32101 ggaaaaaatg catatatata tctaatataa tttttggttc tatttctata aaatattcca
    32161 caaattatag aatcttccaa aaataggtaa gcgctacctt tttggtgtgg tataataagc
    32221 atagaaaaag cccgagcgat taggctcagg ctttcttctt agtgatcacg gtcacatgag
    32281 ataaatttaa tcttgtagta atcagatcgt ttgtaagttt cactgtattc taaaacttgg
    32341 ccagttgatt cgagtttggt gattttagtt tgtaggacag tagggaattg ttcatcgact
    32401 ccgaggactg aagccgcatg ttctggagtt ggaaagacta tttcgttgat ttcttcaaag
    32461 tgttcatcat tcatgtgaat gtggtagtct aacttgaaac gattatagat agaactatag
    32521 tattcaaggt ttggataatt tgcgttgata tattgttctg ggatgtagga tgtatggtag
    32581 atataaacga caccgtttga ttcgcggata cgttcaatct tgtagtagaa ttgatcgccg
    32641 cgtagaccca atttttccaa gtaaacaagc ttgtttccgc gttcaattga aagaacagtt
    32701 accttatcat ctttagcatt gaagagttca atatctgaaa actctacaag cttgtgtttg
    32761 cgtgcacgtg aaacgaaggt tccttttcct tgttggcgga caatatagcc atctttggca
    32821 aggtcgttta aggcgcgaac aactgtgata gagctgacat cgtacattga aatgagttct
    32881 gcttcagtgt aaaatttatc tccactgcta aactgcccag agatgatttt attttttaat
    32941 tcgtctttta tgtattgata tttgggaatt gccatatttt tacctctatt ttccttctcc
    33001 atagaaaatt ttaccataaa agcgaaaaaa atagtagtct tttgaataaa aaattagaat
    33061 aatagtttga aaaattaagc gatataggga ttgctcatat tttatcaatg tattctatac
    33121 aaaattattt taggtcctat attccgaatt taaagagcgt ttgaaatggg tctaaaaatg
    33181 tttgaaacta attgaatgtg tgtataatag taaaaatgca gtaaatatcc cgacaatttc
    33241 tattgacaat tcaaacagat tggtttataa ttaatataac aacaaatgaa agcgcaaact
    33301 ttcgcggtcg gaaggtagtt ttatgacacg atttgagata cgagatgatt tctatctcga
    33361 tggaaaatca tttaagattt tatctggtgc cattcattat tttagggttc ctccagagga
    33421 ttggtatcat tcgctctata acttgaaggc tcttggtttt aatacggtag agacttatgt
    33481 tgcttggaat ttacacgagc ctcgtgaagg tgagtttcat tttgaaggtg atctggattt
    33541 agagaaattt ctccaaatag cgcaggattt gggtctctac gcaattgtgc gtccgtctcc
    33601 atttatctgt gcggaatggg aattcggtgg cttaccagct tggctcttga ccaagaacat
    33661 gcgaattcgc tcatccgacc cagcatatat cgaggcagtt ggtcgctact atgatcagtt
    33721 attgccaaga ctggtgcctc gtttgttgga caatggtggc aatattctca tgatgcaggt
    33781 tgaaaatgag tatggttctt acggagaaga taaggcttac ctgagagcga ttcgacagct
    33841 aatggaagag tgtggcgtaa cctgtcccct ctttacatca gatggtccat ggcgagctac
    33901 tctgaaagct ggaaccttaa ttgaagagga cctctttgta acaggaaact ttggttctaa
    33961 ggcaccttac aacttttcgc agatgcagga attctttgat gaacatggta agaaatggcc
    34021 actcatgtgt atggagttct gggatggttg gttcaatcgc tggaaagaac cgattatcac
    34081 acgggatcct aaggaattgg cagatgcagt tcgagaggtt ttggaacaag gctctatcaa
    34141 tctttacatg ttccacggtg gtacaaactt tggtttcatg aatggttgct cggctcgagg
    34201 aactttggac ctgccacaag ttacgtctta tgattacgat gcccttctgg atgaagaagg
    34261 aaatccaact gctaaatatc ttgcagtcaa gaagatgatg gcaacacatt tttcagagta
    34321 tccgcagttg gaaccactct acaaagagag tatggagttg gatgctattc cactagttga
    34381 aaaagtttct ttatttaaaa ccttagatag cttgtcaagt cctgtagaaa gtctctatcc
    34441 tcaaaagatg gaggagctgg gacaaagtta tggctaccta ctttatcgaa cagaaacaaa
    34501 ctgggatgca gaagaagaaa gacttcgtat cattgatggt cgagataggg cccagctgta
    34561 tgtcgatggt cagtgggtta aaactcaata tcagacagag attggggaag atatttttta
    34621 tcaaggtaaa aagaaagggc tatctaggtt agatatcttg atagaaaata tggggcgtgt
    34681 caactatggg cataagttct tagcggatac gcaacgtaag ggaattcgga caggggtctg
    34741 taaggatctg catttcttac taaactggaa acactatcca ctcccactag acaatcctga
    34801 gaaaattgat ttttcaaaag gatggactca aggacaacca gccttttacg cttatgactt
    34861 tacagtcgaa gagccaaaag atacttacct agacttgtct gagtttggta agggggttgc
    34921 ctttgtcaat gggcagaatc taggacgttt ttggaacgtt ggcccaactc tctcacttta
    34981 tatccctcat agctatctca aggaaggtgc caaccgcatc attatctttg aaacagaagg
    35041 tcaatataaa gaagagattc atttaactcg taaacctaca ctaaaacata taaaggggga
    35101 aaacttatga caattgtagg atgccgtatt gatggacgtt tgatccacgg acaagtagcc
    35161 aatctttggg ctggaaaact aaatgtttca cgcattatgg ttgtagacga cgaagttgtc
    35221 aacaacgata ttgaaaagag tggtttgaaa cttgcgacac caccaggtgt gaaattgagt
    35281 attttgccag ttgagaaagc tgcagccaat attcttgctg gcaaatacga tagccaacgt
    35341 ctctttatcg tggctcgtaa accagaccgc ttccttggtt tggtagaagc aggtgtacca
    35401 cttgaaaccc ttaatgttgg gaatatgtct caaacaccag aaactcgttc tattacacgt
    35461 tctatcaacg tagtagacaa ggatgtggaa gacttccaca aactggcaga aaaaggtgtt
    35521 aaacttactg ctcagatggt tccaaatgat ccaatttcag actttttgag cttattaaaa
    35581 taggaaaaaa atttttagga ggtcattgtt atgatacaat ggtggcaaat tttacttctc
    35641 actttgtact cagcttatca aatctgtgat gagttgacga tcgtttcatc tgcaggttcc
    35701 cctgtatttg ctggtttcat tactggttta atcatgggag atgtgactac tggtttactt
    35761 atcggtggta acttgcaact gttcgttctt ggggttggta ctttcggtgg tgcttctcgt
    35821 atcgacgcaa cttctggtgc ggttcttgcg acagccttct ctgtttcaca aggaattgat
    35881 gcaccgcttg ccattactac aatcgctgta ccagtagcag ctctcttgac ttacttcgac
    35941 gttcttggtc gtatgactac taccttcttc gctcaccgtg tggatgctgc aatcgaacgc
    36001 tttgactata aaggtattga acgcaactac ttgcttggtg cgattccgtg ggctctatct
    36061 cgtgcccttc cagtcttctt tgcccttgct tttggtggtg cctttgtaca atcagtagta
    36121 gacttcgttg aagcctacaa atgggttgca gatggcttga cacttgcagg acgtatgctt
    36181 ccaggtcttg gatttgcaat cttgcttcgt taccttccag ttaaacgtaa ccttcactac
    36241 cttgctatgg gatttggttt gacagctatg ttgactgttc tttactcata tgtaacaggt
    36301 cttggtggcg ctgttgctgg tatcgtaggt actcttcctg ctgaagttgc tgaaaaaatt
    36361 ggtttcgtga acaacttcaa aggtttgtct atgattggta tttctatcgt aggtattttc
    36421 cttgcagtgc ttcacttcaa aaatagccaa aaagtagctg tagcagcacc ttctacacca
    36481 tcagaaagtg gggaaatcga agatgacgaa ttctaattac aaacttacaa aagaagattt
    36541 taatcaaatc aacaaacgta gcttgtttac tttccaatta ggttggaact acgaacgtat
    36601 gcaagcttct ggttaccttt acatgatctt gcctcagttg cgtaaaatgt atggtgatgg
    36661 aactcctgaa ttgaaagaaa tgatgaaagt tcatactcaa ttcttcaata cttcaccatt
    36721 cttccatacc attatcgctg gttttgacct tgccatggaa gaaaaagatg gtgtaggttc
    36781 aaaagacgcc gttaacggta tcaagacagg tttgatggga ccattcgctc ctcttgggga
    36841 tacaatcttt ggttcacttg tacctgctat catggggtca gtcgcagcaa ctatggctat
    36901 cgctggccaa ccttggggga tcttcctttg gattgcagtt gcagtagcgt atgacatctt
    36961 ccgttggaaa cagttggaat ttgcttacaa agaaggggtt aaccttatca acaacatgca
    37021 aagtaccttg acagctttga ttgacgctgc atctgtactt ggtgtcttca tgatgggtgc
    37081 tcttgtagca acagtgatta actttgaaat ttcttacaag ttgccaatcg gtgaaaagat
    37141 gattgatttc caagacatct tgaaccaaat cttcccacgt ttgcttccag caatctttac
    37201 tgcctttatc ttctggttgc ttggtaaaaa aggtatgaac tctactaaag ctatcggtat
    37261 tattatcgta cttgctttgg ctctttctgc ccttggtcac tttgcacttg gaatgtaatt
    37321 ccttatgact aaatcattaa ttttggtgag ccatggtcgc ttctgtgagg agcttagagg
    37381 tagcacagaa atgattatgg gcccacaaga caacatttac acagtagctc ttcttccaga
    37441 agatggccca gaagaattta ctgctaaatt tgaagctgtt attgaagggt tggatgattt
    37501 cctagtcttt gcggatcttc tcggtgggac accttgtaat gtggtgagtc gcttgatcat
    37561 ggaaggtcgt gatattgacc tttacgcagg gatgaatctt ccaatggtga ttgaatttat
    37621 caatgcgagc cttacaggcg cagatgcgga ctacaagagc cgtgctgcag aaagcattgt
    37681 gaaagttaat gacctgttag cgggcttcga tgatgacgaa gatgaataat actcttcgaa
    37741 aatctcttca aactacgtca acgtcgcctt gccgtaggta tatgttactg acttcgtcag
    37801 tcttatccgg caacctcaaa acggtgtttt gagctgactt cgtcagttct atctgcaacc
    37861 tcaaagcagt gctttgagca gcctgcggct agtttcctat tttagttgga actcgattca
    37921 attcatgtga caacgtgaaa atcgttagag cattttatat agaatataca tgggaatgta
    37981 gcttactccc attcccatat ttaatagaaa aagaggaact caatgctaca ttatacaaaa
    38041 gaagacttgc tcgaattggg tgcagaaatc actacgcgtg aaatctacca acagcctgat
    38101 gtatggagag aagcttttga attttatcaa gcaaaacgtg aagaaattgc agcctttcta
    38161 caagaaatcg ctgataaaca tgactatatt aaggttatct tgacaggtgc tgggacttct
    38221 gcttatgtgg gagatacctt gctaccttac tttaaggaag tctatgacga acgcaaatgg
    38281 aatttcaatg ctattgcgac aacagatatc gttgccaaac cagcaaccta tttgaaaaaa
    38341 gatgtggcaa ctgtccttgt gtcttttgct cgtagtggga actcgcctga aagtgtggcg
    38401 actgttgatt tggccaaatc cttggtggat gagctttatc aagtgatgat tacttgtgca
    38461 gcagatggta aattggctct tcaagctcac ggtgatgacc gtaatctctt gctcttgcaa
    38521 ccagctgtct ctaatgatgc tggatttgcc atgacttcta gctttacgtc tatgatgttg
    38581 acagctctct tggtctttga tcctacagaa tttgctgtta agtctgaacg ttttgaagtt
    38641 gtatctagtc ttgcccgtaa agttttagac aaggcagaag atgtcaaaga gctcgttgat
    38701 ttagacttta accgtgtcat ctatctaggc gctggtcctt tctttggact tgctcatgaa
    38761 gctcagctca agattttgga attaactgct ggtcaagttg cgaccatgta tgaaagccca
    38821 gttggcttcc gtcacggtcc aaaatctctt atcaacgaca atacagttgt tttggtcttt
    38881 ggtacaacga cagactacac tcgtaagtac gacttggact tggttcgtga agttgctggt
    38941 gaccagattg ctcgtcgtgt tgtgcttttg agtgatcaag cttttggtct tgaaaatgtc
    39001 aaagaagtgg cccttggttg tggcggtgtc ttgaatgata tttaccgtgt cttcccttac
    39061 atcgtttatg cccaactctt tgccctattg acttcactca aggtagaaaa taaaccagat
    39121 acaccgtctc ctacaggtac agtaaaccgt gtagtacaag gtgtcataat tcacgaatat
    39181 caaaagtaag acagtgttta tgaattcttg acaagaggat ttgtaaatta tcagataaac
    39241 catagattgt cagtacgctt tctatggttt gtttgcttga gagaaatagt aaaaggagaa
    39301 cagaatgaaa gcatacacag agcgtgtatt tggaaatgtt gagggcgagg atgtcttggc
    39361 ctatcgattt gagacagacg gtggctacca acttgaggtt atgacttatg gtgcgaccat
    39421 cttgcgctat gtcgcacctg acaaggctgg aaattttgcc aatgttatct tgggatttga
    39481 tgactttgat agttatgtag gcaatagtcc caagcatgga gcaagtgtag gtcctgtagc
    39541 gggtcgtatt gcaggtgcga cctttgagct caatggtaag acctatgacc ttgaggttaa
    39601 taatgctagc aactgtaatc acagtggttc aactggttgg gattccagct tgtttgaagt
    39661 tgaagaagta agcgatcatg gcttgactct ctacacagag cgtacagatg ggacaggagg
    39721 gttccctgga aatctcaaga tttggatcag ttatcacttg gaagaaactg gtgcctatga
    39781 aatcagctac aaggtaacga ccgatcagga tacgctggtc aatccaacca accacagcta
    39841 tttcaacttg tctggtgatt tcacgcagac gattgaccgt catgtcttcc aactaaacac
    39901 agagggcatt tactcaatcg ctcctgacgg tgttcctgcc aaaactccag aagccaaccg
    39961 tgatgtggtc aaacacatct acaatggtac cttgttgaag gatatctttg cagaagaaga
    40021 tgagcaaatc cagctggcat caggtttgga tcacccattt gcccttcctg taggccatga
    40081 caatgctgga ttcctttatg accaaaattc aggtcgcttc ctgcttttca agacagaagc
    40141 tccttgcttt gtggtctaca cagcaaactt tgtggatgaa agtgtcatca taggaggtca
    40201 gccaatgcta cagcacaatg ggattgctct tgaagcgcaa gctttaccag atgccattca
    40261 cagtgacctt aaaggccaag tcattcttaa agctggtcaa accttcacca gtaagacacg
    40321 ttatgaactt gttgtgaaat aaaaaagctg gtcaaaaagt ctttaaaatt aaaataacgc
    40381 atattgtcag gtgatgaaaa gtttgataat atgcgtttta ttatgaaatg atttacttta
    40441 tattatcctg aaatggtgtt atttttgagt tatctggctt gactttcttg atggaaatta
    40501 tataatagtt gtaataatta taattacaac gagaaaagag gaccatttat gacctatgaa
    40561 tataagagtc acatttattt ggcagagaca gttttaaatg taaaggattt ggccagtcaa
    40621 acagcctttt atcagcaagt tattggttta gaaatcttat ctcaaactga gacagagtcc
    40681 attctaggcc ttggtgaaaa agtcttggta cagctgattc aagcacaaga gagcggagaa
    40741 gtgagggaac attatggtct ttaccatttg gccattctct tgcccacacg caaggctttg
    40801 gctgatgtct tgaaacacct gacagattta cagattcctc ttgtcggcgg tgcagaccat
    40861 ggttacagtg aagctattta cttggaagat ttggagggaa atggcattga actctatcga
    40921 gataagccag tttccacatg ggatattcga gaagatggac gcattatcgg agtgacggag
    40981 gctcttgcgg cgcaggacat ttatgagttg ggggaaagag tagagccctt tatcctggca
    41041 gaaggtacga gaatggggca tattcatctt tccgtcaagg atagtcgaaa gtccagccag
    41101 ttttatcaaa aggtgttagg gctagaggat aaattcagtg tgcctagcgc tagttggatt
    41161 gcggctggag attaccatca tcatttagca gttaacgaat ggggaggaaa aggtctggct
    41221 tcgcgtaagc aaggcttacc aggtttagcc tactatgtca tcgaagtcgc acataaaaaa
    41281 gaactgttaa cgattgccca acgagcacaa gaagttgacg caccaatcaa atggatgaca
    41341 tcgagcaaat tggaaatcac agactcagat ggcatcgtga cccgtattcg tttagcaagg
    41401 taaaattagg aatttttaat aagttataag tattgctagt ttgctttttg aacggtcttt
    41461 ggtaacagaa ctgcgtgagc tggatgggtg agaattttga caaagaagct gattagagat
    41521 ataatgaaga aaaatcgagc aaggaaaaag aaatgacaaa ttcaaagtat attactcgtt
    41581 tgaaacgttc agagggccag ttgcgtggga ttcaaaagat gattgaagga gatcgtgacg
    41641 caactgacag cagtgagatc tagtgtagag cgcgtgattg agatgataat taccgaaaat
    41701 cttactgaat gtatcaatca gccactagat gattctgaag ctcaaaagga acgcttagaa
    41761 aaggctatcc gatacttgat taaacggaaa taaatgaatg ttttgagacg atatgtgcaa
    41821 aggtctatta actattggaa tagtttaatg ggagtcaaaa gaagttgtaa aaaatcttta
    41881 aaattaaaaa aacgcatagt atcaggtatt gaaatgtact gaccccaaaa agttagattt
    41941 tttctgtcta acttttgggg tgcagttcat aagaaccttg gtaatatgcg ttttattatg
    42001 gggagattta tacttttcga aaatctcttc aaaccaggtc agcttcacct tgccgtagat
    42061 atggttactg acttcgtcag ttctatccac aacctcaaaa cagtgttttg agctgacttc
    42121 gtcagttcca tccacaacct taaaacagtg ttttgagcag cctgcggcta acttcctagt
    42181 ttgcacttta attttcattg agtattactt catcttctca tgaaattgag tttttgccca
    42241 gctcctcttg attattctac ttgaccaggc caagcattca taccaccttc tacgttggta
    42301 acggtgaggc cttgggagat gagaaattgg caggtagatg cagagcggac tcctccttga
    42361 caaataacat agtattcatg gtcaggtttg agttctttgt agccttgctc taaggtactt
    42421 aatggaagat ttttggcacc tggtgcatgt cctgcttgga attcatgtgc ttcacggaca
    42481 tcgataagtt ctagattttc attttggtat tttccataaa agtcagccat gctgatacta
    42541 gtttccatat tctactcctt ctgggttaac cattttgtat agtgaataag cgccgtcaag
    42601 gttttgggcg gtaaatcctg cttgcttgag gataggctct gcgatatagc tgcgcaaacc
    42661 actgtggcag ctgacgatgt aggcttgttt tttgtccagt tcatcagctt cctccttgac
    42721 actcggtcag attttgatac aatagtacaa aattagagga ggcaggctat gattcagaaa
    42781 catgcgattc ctattttaga gtttgatgac aatcctcagg cggttatcat gcccaatcac
    42841 gaggggctgg acttgcagtt gccaaagaag tgtgtttatg catttttagg tgaggagatt
    42901 gaccgctatg cgagggaagt aggggcgaac tgtgttggcg aatttgtttc tgccaccaag
    42961 acctatccag tctatgtcat caactacaag ggtgaggagg tctgtctggc tcaggctcct
    43021 gttggctccg ctccagcagc ccagtttatg gattggttgg ttggctatgg tgtggagcag
    43081 attatctcta ctgggacctg tggtgtccta gctgatatag aggaaaatgc ctttctagtc
    43141 cctgttcgcg ctctgcgaga tgaaggagcc agttaccact atgtggcacc ttctcgttat
    43201 atggaaatgc agccagaggc tattgctgct attgaggaag ttttggaaga cagagggatt
    43261 ccttatgaag aagtcatgac ctggacgaca gacggttttt accgagaaac ggctgaaaag
    43321 gtggcttatc gtaaggaaga aggctgtgct gttgtggaga tggagtgttc cgctcttgcg
    43381 gcagtagctc aattgcgtgg ggttctctgg ggtgaattgt tgttcacagc agattctcta
    43441 gcggacttgg accagtacga cagtcgtgac tggggctcgg aagcttttaa taaggcgcta
    43501 gaactgagtt tagcaagtgt tcaccacctt tagttgtact ggcaaaggat ttgttttatc
    43561 ataaaatgtc tagctcatac ttttcaaaaa tatgtttaaa cgaggtcacc ttcctcttgt
    43621 cctaggcatg ttgaggttgg gaaaaatctt taaaatcaga aaaacgtatc atatcaggtg
    43681 atgaaaactt tgatactatg cgttttatgt tggtaagatt tagagtgaga tgaaatgata
    43741 ctcttcgaaa atctcttcaa accaggtcag cttcaccttg ccgtatagat gttactgact
    43801 tcgtcagttc tatctgcaac ctcaaaacag tgttttgagc tgacttcgtc agttctatcc
    43861 acaacctcaa aacagtgttt tgagcaacct gtgactagct ttctaagcga tgccttggtt
    43921 ctcattgcct ataatcaaaa agagaaattt tctcctgaaa agcatataga gtagctggcg
    43981 ttaaaagctc ctgtcttgct tttttgacct atagtcacat ctatcaagta ttgttcttgc
    44041 ctaagctatc aataaaaagg tggcattttt taggcttggt gttagtagat tttgccttat
    44101 cctatctaag tcatttcgaa ctttttatgg tacaatggaa acatgttatt caaattatct
    44161 aaggaaaaaa tagagctagg cttatctcgt ttatcgccag cccgtcgtat ttttttgagt
    44221 tttgccttgg tcattttact aggctctctt cttttgagct tgccctttgt ccaagttgaa
    44281 agctcacgag cgacttattt tgatcatctt ttcactgctg tctctgcagt ctgtgtgaca
    44341 ggtctctcaa cccttccagt agctcacacc tataatatat ggggccaaat aatctgtttg
    44401 ctcttgattc agatcggtgg tctagggctc atgaccttta ttggggtttt ctatatccag
    44461 agcaagcaaa agcttagtct tcgtagccgt gcaactattc aggatagttt tagttatgga
    44521 gaaactcgat ctttgagaaa gtttgtctat tctatttttc tcacgacctt tttggttgag
    44581 agcttgggag ctattttgct tagttttcgc cttattcctc aacttggctg gggacgtggt
    44641 ctttttagtt ccatttttct agcgatctca gccttctgta atgccggttt tgataattta
    44701 gggagcacca gtttatttgc ttttcagacc gatttactgg tcaatctggt gattgcaggc
    44761 ttgattatta caggcggcct tggttttatg gtctggtttg atttggctgg tcatgtagga
    44821 agaaagaaaa aaggacgtct gcactttcat actaagcttg tactattgtt gactataggt
    44881 ttgttgttat ttggaacggc aactactctc tttcttgagt ggaacaatgc tggaacgatt
    44941 ggcaatctcc ctgttgccga taaggtttta gttagctttt ttcaaacagt gacgatgcga
    45001 acagctggct tttctacgat agattatact caggctcatc ctgtgactct tttgatttat
    45061 atcttacaga tgtttctagg tggggcacct ggaggaacag ctgggggact caagattacg
    45121 acattttttg tcctcttggt ctttgcacga agtgagcttc taggcttgcc tcatgccaat
    45181 gttgcgagac gaacgattgc gccgcgaacg gttcaaaaat cctttagtgt ctttattatc
    45241 tttttgatga gcttcttgat aggattgatt ctgctaggga taacagccaa aggcaatcct
    45301 ccctttatcc acctcatatt tgaaaccatt tcagctctta gtacagttgg tgtaacggca
    45361 aatctgactc ctgaccttgg gaaattggct ctcagtgtta tcatgccact tatgtttatg
    45421 ggacgaattg gtcccttgac cttgtttgtt agcttggcag attaccatcc agaaaagaaa
    45481 gatatgattc actatatgaa agcagatatt agtattggtt aagaaaggaa agatcatgtc
    45541 agatcgtacg attggaattt tgggcttggg aatttttggg agcagtgtcc tagctgccct
    45601 agccaagcag gatatgaata ttatcgctat tgatgaccac gcagagcgca tcaatcagtt
    45661 tgagccagtt ttggcgcgtg gagtgattgg tgacatcaca gatgaagaat tattgagatc
    45721 agcagggatt gatacctgcg ataccgttgt agtcgcgaca ggtgaaaatc tggagtcgag
    45781 tgtgcttgcg gttatgcact gtaagagttt gggggtaccg actgttattg ctaaggtcaa
    45841 aagtcagacc gctaagaaag tgctagaaaa gattggagct gactcggtta tctcgccaga
    45901 gtatgaaatg gggcagtctc tagcacagac cattcttttc cataatagtg ttgatgtctt
    45961 tcagttggat aaaaatgtgt ctatcgtgga gatgaaaatt cctcagtctt gggcaggtca
    46021 aagtctgagt aaattagacc tccgtggcaa atacaatctg aatattttgg gtttccgaga
    46081 gcaggaaaat tccccattgg atgttgaatt tggaccagat gacctcttga aagcagatac
    46141 ctatattttg gcagtcatca acaaccagta tttggatacc ctagtagcat tgaattcgta
    46201 aagagggatg acccctcttt tttgatgccc aagatggcaa atagagacag aagccccttg
    46261 tcttctagtt aaaagttctt caaaggctgg actttatgat aaaatagaaa gaagtgacaa
    46321 gagagagtaa tactcaatga aaatcaaaga tcaaactagg aaactagctg cgggctgctc
    46381 aaaacactgt tttgaggttg tggatagaac tgacgaagtc agctcaaaac actgttttga
    46441 ggttgcagat agaactgacg aagtcagtaa catctatacg gcaaggcgac gttgacgcgg
    46501 tttgaagaga ttttcgaaga gtataagaaa aaatcagtcc cctaaaggag cagattatga
    46561 agttattgtc tatcgccatt tctagctata atgcagcagc ctatcttcat tactgtgtgg
    46621 agtcgctagt gattggtggt gagcaagttg agattttgat tatcaatgac gggtctcagg
    46681 atcagactca ggaaatcgct gagtgtttag ctagcaagta tcctaacatc gttagagcca
    46741 tctatcagga aaataaaggc catggcggtg tggtcaattg cggtttggca gaggcttctg
    46801 ggcgctattt taaagtagtt gacagtgatg actgggtgga tcctcgtgcc tacttgaaaa
    46861 ttcttgaaac cttgcaggaa cttgagagca agggtcaaga ggtggatgcc tttgtgacca
    46921 attttgtcta tgaaaaggaa ggtcagtctc gtaagaagag tatgagttac gagtcagtct
    46981 tgcctgttcg gcagattttt gactaggacc aggtcggaaa tttctccaaa ggccagtata
    47041 tcatgataca ctcgctgatt tatcggacag atttgttgcg tgctagccag ttctaactgc
    47101 ctgaacatac tttttatgtc gatgatctct ttgtctttac gccccttcag caggtcaaga
    47161 ccatgtacta tctgcctgtc gatttctatc gttatttgat tgggcgtgag gaccagtctg
    47221 tcaatgagca agtgatgatt aagcgcattg accagcaact caaggtcaat cgactcttgg
    47281 tagaccagct tgatttgtcc caagtgagtc atcctaaaat gcgagaatat ctgctgaatc
    47341 atattgaaat cacgacggtg atttccagta ccctgctcaa ccgatctgaa acagcggagc
    47401 atctggcaaa aaaacgccaa ttgtggacct atattcagca gaaaaatcca gaagtctttc
    47461 aggctattcg taagaccatg ttgagccgtt tgaccaaaca ttctgtcttg ccagatcgca
    47521 aactgtccaa tgtcgtctat caaatcacca aatctgttta tggatttaat taatataagt
    47581 gttttataag agggatttaa gaaaaatttt aactttttct tagtcctttt taatttcagg
    47641 agattatact agagtcatca aataaagaaa gactctaagg agaatcctat gaaattcaat
    47701 ccaaatcaaa gatatactcg ttggtctatt cgccgtctca gtgtcggtgt tgcctcagtt
    47761 gttgtggcta gtggcttctt tgtcctagtt ggtcagccaa gttctgtacg tgccgatgtg
    47821 gtcaatccga ccccaggtca agtcttacct gaagagacat cgggaacgaa agagggtgac
    47881 ttatcagaaa aaccaggaga caccgttctc actcaagcga aacctgaggg cgttactgga
    47941 aatacgaatt cacttccgac acctacagaa agaactgaag tgagcgagga aacaaactct
    48001 tctagtctgg atacactttt tgaaaaagat gaagaagctc aaaaaaatcc agagctaaca
    48061 gatgtcttaa aagaaactgt agatacagct gatgtggatg ggacacaagc aagtccagca
    48121 gaaactactc ctgaacaagt aaaaggtgga gtgaaagaaa atacaaaaga cagcatcgat
    48181 gttcctgctg cttatcttga aaaagctgaa gggaaaggtc ctttcactgc cggtgtaaac
    48241 caagtaattc cttatgaact attcgctggt gatggtatgt taactcgtct attactaaaa
    48301 gcttcggata atgctccttg gtctgacaat ggtactgcta aaaatcctgc tttacctcct
    48361 cttgaaggat taacaaaagg gaaatacttc tatgaagtag acttaaatgg caatactgtt
    48421 ggtaaacaag gtcaagcttt aattgatcaa cttcgctcta atggtactca aacttataaa
    48481 gctactgtta aagtttacgg aaataaagac ggtaaagctg acttgactaa tctagttgct
    48541 actaaaaatg tagacatcaa catcaatgga ttagttgcta aagaaactgt cgaaaaagct
    48601 gttaaaga
//
LOCUS       DAVLDI010000010        46018 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLDI010000010 DAVLDI010000000
VERSION     DAVLDI010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46018
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.010"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(564..2291)
                     /gene="ezrA"
                     /locus_tag="VXD01_000529"
     CDS             complement(564..2291)
                     /gene="ezrA"
                     /locus_tag="VXD01_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV0600966.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2373..4319)
                     /gene="gyrB"
                     /locus_tag="VXD01_000530"
     CDS             complement(2373..4319)
                     /gene="gyrB"
                     /locus_tag="VXD01_000530"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV0600967.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4334..4897)
                     /locus_tag="VXD01_000531"
     CDS             complement(4334..4897)
                     /locus_tag="VXD01_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0600968.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLVLYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4982..5536)
                     /locus_tag="VXD01_000532"
     CDS             complement(4982..5536)
                     /locus_tag="VXD01_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV0600969.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5547..6770)
                     /locus_tag="VXD01_000533"
     CDS             complement(5547..6770)
                     /locus_tag="VXD01_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0600970.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6807..9257)
                     /locus_tag="VXD01_000534"
     CDS             complement(6807..9257)
                     /locus_tag="VXD01_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV0600971.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9457..10386)
                     /locus_tag="VXD01_000535"
     CDS             complement(9457..10386)
                     /locus_tag="VXD01_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0600972.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDLLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10526..10813
                     /locus_tag="VXD01_000536"
     CDS             10526..10813
                     /locus_tag="VXD01_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV0600973.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10847..12181)
                     /gene="ciaH"
                     /locus_tag="VXD01_000537"
     CDS             complement(10847..12181)
                     /gene="ciaH"
                     /locus_tag="VXD01_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV0600974.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12171..12845)
                     /gene="ciaR"
                     /locus_tag="VXD01_000538"
     CDS             complement(12171..12845)
                     /gene="ciaR"
                     /locus_tag="VXD01_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV0600975.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12954..15500)
                     /locus_tag="VXD01_000539"
     CDS             complement(12954..15500)
                     /locus_tag="VXD01_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV0600976.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15623..16063)
                     /locus_tag="VXD01_000540"
     CDS             complement(15623..16063)
                     /locus_tag="VXD01_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV0600977.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16038..16907)
                     /locus_tag="VXD01_000541"
     CDS             complement(16038..16907)
                     /locus_tag="VXD01_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV0600978.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQEFVKDYLDTICSFYLGKEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLDRILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16885..17385)
                     /locus_tag="VXD01_000542"
     CDS             complement(16885..17385)
                     /locus_tag="VXD01_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0600979.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKARGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVISYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17396..18094)
                     /locus_tag="VXD01_000543"
     CDS             complement(17396..18094)
                     /locus_tag="VXD01_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV0600980.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGFQVYGVDQGENPLLEGDF
                     HFLQRDLTLDLEPIFGWCPQVDVLCNTAGVLDDYKPLLEQTAQEIQEIFEINYMTPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18087..18323)
                     /locus_tag="VXD01_000544"
     CDS             complement(18087..18323)
                     /locus_tag="VXD01_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV0600981.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(18423..19349)
                     /locus_tag="VXD01_000545"
     CDS             complement(18423..19349)
                     /locus_tag="VXD01_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV0600982.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19424..20239)
                     /locus_tag="VXD01_000546"
     CDS             complement(19424..20239)
                     /locus_tag="VXD01_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600983.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LHYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFLLFRGFKKIKWSEV"
     gene            complement(20243..20563)
                     /locus_tag="VXD01_000547"
     CDS             complement(20243..20563)
                     /locus_tag="VXD01_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0600984.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(20815..20895)
                     /locus_tag="VXD01_000548"
                     /pseudo
     CDS             complement(20815..20895)
                     /locus_tag="VXD01_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(20939..22936)
                     /gene="metG"
                     /locus_tag="VXD01_000549"
     CDS             complement(20939..22936)
                     /gene="metG"
                     /locus_tag="VXD01_000549"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV0600985.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23060..24319)
                     /locus_tag="VXD01_000550"
     CDS             complement(23060..24319)
                     /locus_tag="VXD01_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0600986.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKFQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24321..25022)
                     /locus_tag="VXD01_000551"
     CDS             complement(24321..25022)
                     /locus_tag="VXD01_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0600987.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25006..26205)
                     /locus_tag="VXD01_000552"
     CDS             complement(25006..26205)
                     /locus_tag="VXD01_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV0600988.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            26470..27816
                     /gene="gor"
                     /locus_tag="VXD01_000553"
     CDS             26470..27816
                     /gene="gor"
                     /locus_tag="VXD01_000553"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV0600989.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNRESYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            28013..28549
                     /locus_tag="VXD01_000554"
     CDS             28013..28549
                     /locus_tag="VXD01_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV0600990.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            28605..28685
                     /locus_tag="VXD01_000555"
                     /pseudo
     CDS             28605..28685
                     /locus_tag="VXD01_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(28754..28969)
                     /locus_tag="VXD01_000556"
     CDS             complement(28754..28969)
                     /locus_tag="VXD01_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV0600991.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PNHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            29067..29387
                     /locus_tag="VXD01_000557"
     CDS             29067..29387
                     /locus_tag="VXD01_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600992.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(29418..29756)
                     /locus_tag="VXD01_000558"
     CDS             complement(29418..29756)
                     /locus_tag="VXD01_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600993.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(29768..30487)
                     /gene="trmD"
                     /locus_tag="VXD01_000559"
     CDS             complement(29768..30487)
                     /gene="trmD"
                     /locus_tag="VXD01_000559"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV0600994.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(30477..30995)
                     /gene="rimM"
                     /locus_tag="VXD01_000560"
     CDS             complement(30477..30995)
                     /gene="rimM"
                     /locus_tag="VXD01_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV0600995.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(31026..31814)
                     /locus_tag="VXD01_000561"
     CDS             complement(31026..31814)
                     /locus_tag="VXD01_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0600996.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDEYGPELYLKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            31954..32163
                     /locus_tag="VXD01_000562"
     CDS             31954..32163
                     /locus_tag="VXD01_000562"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0600997.1"
                     /translation="MLVINDCGFVFLKDSLGKVNMLDSSNSDGVVNDISQFSGKFLVR
                     ILSLLFDQSAYSKPRLLLRLPPLTS"
     gene            complement(32391..32630)
                     /locus_tag="VXD01_000563"
     CDS             complement(32391..32630)
                     /locus_tag="VXD01_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV0600998.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(32650..32922)
                     /gene="rpsP"
                     /locus_tag="VXD01_000564"
     CDS             complement(32650..32922)
                     /gene="rpsP"
                     /locus_tag="VXD01_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV0600999.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33092..33301
                     /locus_tag="VXD01_000565"
     CDS             33092..33301
                     /locus_tag="VXD01_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601000.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33780..33992
                     /locus_tag="VXD01_000566"
     CDS             33780..33992
                     /locus_tag="VXD01_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601001.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            34075..34878
                     /locus_tag="VXD01_000567"
     CDS             34075..34878
                     /locus_tag="VXD01_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV0601002.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(34934..36475)
                     /locus_tag="VXD01_000568"
     CDS             complement(34934..36475)
                     /locus_tag="VXD01_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0601003.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(36477..36959)
                     /locus_tag="VXD01_000569"
     CDS             complement(36477..36959)
                     /locus_tag="VXD01_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV0601004.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(36959..38044)
                     /gene="rlmN"
                     /locus_tag="VXD01_000570"
     CDS             complement(36959..38044)
                     /gene="rlmN"
                     /locus_tag="VXD01_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV0601005.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHIMVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(38065..38595)
                     /locus_tag="VXD01_000571"
     CDS             complement(38065..38595)
                     /locus_tag="VXD01_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV0601006.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(38752..39357)
                     /locus_tag="VXD01_000572"
     CDS             complement(38752..39357)
                     /locus_tag="VXD01_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV0601007.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(39530..40567)
                     /locus_tag="VXD01_000573"
     CDS             complement(39530..40567)
                     /locus_tag="VXD01_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV0601008.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(40601..41536)
                     /locus_tag="VXD01_000574"
     CDS             complement(40601..41536)
                     /locus_tag="VXD01_000574"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV0601009.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(42089..43279)
                     /locus_tag="VXD01_000575"
     CDS             complement(42089..43279)
                     /locus_tag="VXD01_000575"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV0601010.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(43494..44837)
                     /locus_tag="VXD01_000576"
     CDS             complement(43494..44837)
                     /locus_tag="VXD01_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0601011.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(45217..>46018)
                     /locus_tag="VXD01_000577"
     CDS             complement(45217..>46018)
                     /locus_tag="VXD01_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000465985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV0601012.1"
                     /translation="YTPQVTEETIKVGQTPDLTDNVTNLPNLPAGTKVVDITPAGQID
                     TTKPGTYTGKVRVDYPDGSSTEVSVSVNVLPAPETQTYKVTYRFESATADNNLPAEVL
                     SLLPQSGTYTTSSSVAIAFVPEAPMPVEVAVANGTWTFLGYQEVEEGSNLTFVGKWVF
                     EAKQDPSPQPQPAPTPQPAPQPNPVPPVNPGGEQGTDNNQADRHQSEQPRKPEENPPA
                     QGPAGEKEKQATLPNAGSTAPLSLTGLVTSSLLAGLAVLLLGRKRKDD"
BASE COUNT        13601 a        10069 c         8331 g        14017 t
ORIGIN      
        1 ttggatttct tctttagttg attttatatt actattatat aatacttttt tattttagtc
       61 tagtataaat agcgagaaat atctatccta tcttctagaa tgtcttccaa acgagaaaac
      121 tctcgtaaac aaagaggttt tagaggccta tttaccgtgg gactaaagtt gtacaagaaa
      181 agtgcaaata agaaatctcc agattaggaa ctatccgtga gttctctagt ctggagattt
      241 ttcaatagac ttcgttattg gacggttacc aagttactca aagtacagat ttgaagctgc
      301 agataagact gacgaaatca ctttaatact aaatgaaaat caaaaagcaa actaagaagc
      361 tagcctcagg ctgtacttga gtacggtaag gcgacgctga cgtgatttga agagattttc
      421 gaagagtata aaacactgtt ttgaggtggt ggataaatcg gctgggtaaa aactcaatct
      481 caggagaaaa tgaagtaaat ctccccacaa ctatagaaaa agatttgatt ctgctcctca
      541 cacaataaaa tctttttctt ttattaaaaa cgaatcgttt cacgtgtttt ctcatatgag
      601 gtaacaaagc gattggttac accaggctct gccacttcca atgcttgaga aatcttgtca
      661 aatgaagcgt gataatcaaa ttctttttca aaaatatcta aagcttcgtt aaatgcttct
      721 tgaatgcgtt catcaaatga gcgatagcgg ttagaatatt gcaagagttg ctctgtcaaa
      781 gttgcatatt gtacaatatt ataagtttcc gtttctaaag cttccatatc attcgttgca
      841 atttcaagaa ctcgggtaac agattcaatg ttaatcattt tttgttctaa ctcaaccatt
      901 aaatcctcgg tattattgct tgccgtaaag aataacttca agaaagtttg tggaatacct
      961 ggcagattgc gtttttccat gtatcgcttg atagtatgga gacgattgac ataaacattg
     1021 gccttttgac gtgcattaat atcatctttc tcaatttgtg tcaggcgctc actaactgaa
     1081 atttgctcat cttcaatatc ttttagttga gtttgtaaat cctcaagatt ttcttcaaga
     1141 actgaataag cttgggttgg ttcttcttga ttcgaagtta cctcaacaat agctgcctca
     1201 aaactctcta attctgtctg aatacgacga acatggcttg cagctgtctc aggaagtaaa
     1261 taggtcttgt tcaaacgtgc aatatcttct cccaataaag tattattctc tttcatatgt
     1321 tgaaggtaag ttggaagagt tgcaagtaga ttttccacta ctttctgagc agcaatttct
     1381 cgagtaaaaa tatcatacaa ggcattgatt tcctcttgtg cctgtccatt ctcatattca
     1441 gcattatcca attccaactg acgaatattc tcttggtttt tcttgaatgc ttcataaagc
     1501 aagtggaaac gcgcttcaat atccgtttca acaaaatgat aattagcatc aattagttta
     1561 cgataaccgg cttccaaatc ctgtaattga tctggcaatt ctgtagaaag cgtcgtaacc
     1621 aaggctggaa cacgatccac aatatgactt aaggccaaaa tgtgattttc tgtattatcc
     1681 aaaatcactg cggcttccac agggtcaccc gatgaattca aggttacaaa ttgtgaaaat
     1741 tcagattgga tattttctaa ttgtttttca atttcatcca aggcttgacc atactgttct
     1801 gaattttcag caactctatg ctgaagttcc tcaaataaat ccaaagcatg aagaacacga
     1861 ccactatttt tagattcttg cttctctaag tctgccaaag cattgcgaat tgccgcaata
     1921 tcttcttcaa tcaaagtaat ttgactctca atttggtcaa tttgatgact ggccttgaga
     1981 aaacgaaatg aatggttata gccttctgct tcaaagagat tattttcaat atcggcaaaa
     2041 gagttgagag ataaatcgac ccatttttga ttccattcac ggaaagctac ttgactttgt
     2101 ccaatcaagt gcatattttt tacagcttct acttcatcat ttactggaag attgtatagt
     2161 tcttcttttc tttcttctag cgcctctaat ctcccctcgt ttcgcttacg tagaaagatt
     2221 gccactacat aagccagaac taaaatgact gcaattgcaa ccattaaata aattagttgt
     2281 ccattagaca tatcaaactc cttttttact tgaaacaatc gtaacgatta tatcatattt
     2341 tttagaccaa gggaactact tctccctatt ttttagacat caagtgtact atagacagca
     2401 ttttcttcga taaactcacg acgaggctct actcgatccc ccatcaacat atcaaagatt
     2461 ttatctgctt ctgcagcatc atctacagaa actctagcca tcaagcgatg ttcgggatcc
     2521 atggttgttt cccacagctg atgatcgtcc atttcaccta gccccttata acgctgaata
     2581 gtcggtttgg tacgaccttc actataacgg gctaaagctt cttggagttt gatttcttga
     2641 tctgcacccg gctggatata ttctttaatc tcgcttccaa ccttgacacc atagattggt
     2701 ggttgggcaa tataaacata tccagcttct aggattggtt tcatataacg ataaatcaag
     2761 gttaaaagaa gggtacgaat gtgggctcca tcgacatcgg catcggtcat caaaacgagt
     2821 ttttggtaac gggctttcga aacatcaaat tctgcgccaa atcctgttcc catggctgtg
     2881 aaaagactac gaatttcttc gttggctaga atcttatcca tacttgcttt ttcaacattc
     2941 aaaatcttac cgcgaattgg aaggatagcc tgaaactcac ggttacgacc agatttggct
     3001 gatccaccag ctgagtctcc ttcgacgatg aagagttctg tttcagcagg gttattagaa
     3061 gaacagtctg ctagtttccc tggaaggttg gaaatttcca aaccagattt tttacgtgtg
     3121 acttcacgcg cacgcttggc agccacacga gccttggcag ccaaaattcc tttttctacg
     3181 atacgtttgg caatctgtgg attttccatg aggaaatcgg agaaggcttc actgaagagg
     3241 cgattggtaa tcttgaccac ttcgctattt cccaatttgg tcttggtttg tccttcaaac
     3301 tgtggatttg ggtgtttaac tgagataact gcagttaagc cttcgcgaac atcttcccct
     3361 gttaaattat cttcattgtc tttcagtaac ttattcttac gagcataatc attgataaca
     3421 cgagtcagtg ccgtacggaa accttgttca tgcgttccac cttcatgggt atgaatatta
     3481 ttggcgaaac tcatgacatt ttcatggtaa cctgttgtgt actgcatggc tacctcaact
     3541 gtaatatcat ccatctcacc gtctgtatag attggtgtat caaagattac atccttgttc
     3601 tcgttgatat attcaacgta actagcaatc ccaccttcat aatgataatg cttggtttgt
     3661 tccaaacctt ggcgcttatc agtgatagaa atttgaagac cgcgatttag aaaggccaac
     3721 tcttgaatcc gtttatttaa tttatcaaaa tcaaagattg ttgtttcagt gaaaatttct
     3781 gggtccggtg tgaagtgaac cgttgttcca gttctatctg tatccccaac cacctcaagg
     3841 tctgcaacaa catgaccacg acggtattct tggtaatgaa tcttaccgtt tttatggaca
     3901 tgaacgtcta attgagtgga aagggcatta actactgacg accccacccc gtgaaggcca
     3961 cctgaaacct tgtatccacc accgccgaac tttcctccag catgaaggac tgtaaagacg
     4021 gtctcaacag caggacggcc tgttttttcc tgaatatcga ctgggatacc acgcccatca
     4081 tccacaacag taatcgaatc atctggctca ataaaaactt gaatatggct ggcaaatcct
     4141 gccaaggcct cgtcaattga gttatcaaca atttcccaga ctagatggtg aagaccttct
     4201 tttgaggttg atccaatgta catccctgga cgcatacgaa cagcctctaa gccctctaaa
     4261 acttgaattt gactggcatc ataatcctgt gcctgcagat ttttgatttc ttctgtcatc
     4321 ttattccttt ttcttatatg tctaatactt gtcttaaatt cacgatactg gtaaacaagt
     4381 gggtatcaag tcctgcagct tgacctgctt cgatatcaat cggccgatca ccaatgacaa
     4441 gaccagagct aatctgatac ttttctctta aataaagcat ggattcggga tttggctttc
     4501 tcttaaagcc tgagctagaa gtcaccactt ctgtaaaata agctgctata gaggtttttt
     4561 ctaaaatttc caaaacctga tcatttcgat gagagaccaa aaaatgacgg ccaccttgat
     4621 ttgaaatgac ttccaatagg tcagaaactc cttcaaataa aatcgggtgt tcaagctctc
     4681 tggcttcatt ttccttgtac ttttctaaaa aattctctaa attgggagcg aatgtctcaa
     4741 tcgcaaaagg agtagaaacc tttaaagctt gatagacact gtcatggtct tgtgtgatac
     4801 catacagtac caatgtttca acaaatgcag ctgttgaagt ttcataatta tccagtaaag
     4861 ttccacctaa atcccagatg taatcgtgat atttcatacc cttcattata gcattttttt
     4921 atgaaaaaag cgatgatttc cctgagtttt ccacataaaa aacgagagaa taactcccgt
     4981 tttactgatt tttaccaaag acatctcgat agagcattcc tgttcgtaaa ctctctgcgt
     5041 cccctcctag ttgctccacc aactcgtagg caaaggcaag ggctgttgaa ggaccccgac
     5101 tggttgtcaa ctgaccatct accactactg tttccttgac gtagtgacca tcaaggattt
     5161 gctcttgaac gccgtcataa caagtgtatc gcttattttt caatatctct gcttgattga
     5221 gggcaattgg tgccgcacaa atggctgcta gtttcttccc ttcttgctcg aagctttgca
     5281 attcttgaat caaggtctga ttatcacgta aatgtgcaga accaggcata cctccaggaa
     5341 gaacaatcat atcatagtct gataaatttc catcaaagac atgatctgct cttacttgga
     5401 ttgcatgcga acccgttact tgctcttcaa aaccaaccat atcacatgtg atattggctc
     5461 gacgcaagac atctacaact gtcaaggctt caatttcttc aaagccctga gctaacataa
     5521 ctgctacttt taccatgatt ttctccttat ttaatttgtt ttaatacaac ctttttccgt
     5581 ttgaatggga cttttccgct cttttcttca gctagattag tctggtaact catcgataaa
     5641 agcaaaccaa caccaatcag attactgata atagctgatc ccccttgcga aatgaaaggc
     5701 aagggaatcc ccgtcaaagg aagtagtcca gtcacagcac cgatattctc aaagatgtgg
     5761 aagagcaaca tcataatcaa acctgtggaa atataagtgt agaactggtt atttgattta
     5821 agagtaatct tcaacatacg gtaaatcaac atgagataga gggcaataac caggacagag
     5881 ccaataaagc caaaatcttc tgcaataacc gtaaaaatca tatctgactc tcgaactggg
     5941 ataagcagat tcgaagcatt aaatccctga ccaaataagc caccactccc aatggcaatc
     6001 tgcccttgag cctgctggta agtcgttgtt tgggcaaact caaagggatt gagccaagcc
     6061 aaaatccgat tgatttggta ggtcggcatt ccaatctggt gaagaaaagc tcgtccgtcc
     6121 ttgctaataa agatagctaa gaaaccagca actcctgtta cagcagtcac aaatactggg
     6181 ataataattt tccaagaaac ccctgataat aaaacgattc ctgagaaaat ggctacaaaa
     6241 accaaagccg tccccaagtc actttgaagt gctaaaagaa ctaggactgg aatggtaaag
     6301 agaatcatcc agaaaattaa caaaaagtcc agcgaaaccg tgcgtctcca ttccttatgt
     6361 ttctttgtaa attggacaat gacacgagcc aacatgagga tataggatat cttcataaat
     6421 tctgacggtt gaaatagggt aattccattt attgataccc agtttttggc acccgttgat
     6481 gcaactaagc ttggattata aaatacaatc ggcaagatca taagtcccaa gcctaaaata
     6541 tatagaaagg gggtcacctt ccaaagaaat tctgtattaa agagcatgac cacaaaacca
     6601 atcacaagcc ccaaggcaat ccaggcgacc tgctgcccta aaatgggcag aatattattg
     6661 ggataatcat gactaacggc tatatagata gccaccacac cgatgaccag tagaaaaaat
     6721 actggcaaga gcaaactgta atcgactctt gagtcgagag aacgtttcat atatactaac
     6781 cttatacttt catacaatac tatttatcaa agttcattaa aaaatctatc aatagcctcg
     6841 tcaacttcgg atcgagagat ggttttaaca gtcgcttctt ctgctagaga tgctactatt
     6901 tgtttgccgt atcgttttcc gacgattctc ctatccaaaa taagagttaa ggaacgttgg
     6961 tattcacgtc tcatacttct tcccaaagcc tgttttaaac gaataatggc cattggcaat
     7021 tgataatcat aaaaggcatt tttcccttct tgattcagtt cttgattaat ctttttcgtc
     7081 aagggttctt gaggattttg gaaaggaagc ctcggtacaa cttgaatcac aaaaggatgg
     7141 cttgaaaaat caactccctc ccagaaactt gctgcaccaa gcaagatttg ttgttcacct
     7201 ttttcaaagc gtttctttag ctgatgaaca tccccatttt tatactgggc caagtggcta
     7261 actgtaagta aatccgatac tgctagaagc atgtctttag cggtaaagag aaccaaaatc
     7321 ggttgctgga aagcttgaat ttccactagt aaagcagcta cctctctggc atagacttct
     7381 aaggaggttt ctgttaccag agggaaatct ttgaccataa ccacttcttg ttcctgtttt
     7441 ccccgagatt caatcttgac aaatttggct tcaggatagc ctaaaaggtc tgccaaagaa
     7501 accctctgac taatctcaag agtagccgat actcccaaga cttggcaact ctcaggaagt
     7561 aaagaggaca gaagagtacg gcctgatttt gtagaagaaa tctgaatttt cttttgactc
     7621 gtttcagtta cttcaagcca gtaatcacct tcagctgtaa aatagcgaac cagctcatca
     7681 aagccttcta cttctaattc tgaaaaatac tgatggagat tgtccagaga atctaagata
     7741 tttttcctag atttaccaga ctgaaattgt tctatcaagt agagacactc aaagcgaata
     7801 ctttctagta tccgttgttg aaccctgttt tcttccccta ctaaagcctt atcaattaaa
     7861 tcgataatag attgtatatc gtaggtctct tgaagcagat tttctagagc taacaaaatc
     7921 ttttggactt catcaataat cagtaaacgg tcactgacaa attcaggatt atcttcaagt
     7981 ctggtcacga gataggcatg attagtcact aaaagcttgc aagtctctgc cctttcttga
     8041 ctacgtttcc aaaaatcttc cgtcacaaat aagctctggg atgataaatt cccatcatga
     8101 cgaaggtctg ctagaaaatg ttggtaacgg tagagttgcc cgatttcatc caaatctcct
     8161 gtctctgtct cagtaagcca gaccaagact tgcattttaa agcgtctaaa taagcgattt
     8221 tcatcatttt cctgcaagga atgataaaag gcatccaact tcagataatt ttgtggtccc
     8281 tttaagctat gaatatctgt atggaacact tccttgagac gtttaccttc ttcttccatg
     8341 atttgatttt gaagaatctt tgtcggaaca ctaagaacaa tttgtcgctc tttggattga
     8401 gataaagcgg gtaagagata gccataggtt ttcccaatcc ctgtcggcgc ttgaatcaga
     8461 gagacaggtt catctttcaa tagcaagcca acctctttag caaaactttc ttgttcctcc
     8521 ctcacttcaa ggttcaacag agaaatattt ttagaaaagt cttgagatag ttttcgtagc
     8581 tccagagaag ctgccgtttt cttaaaatac agaccttgaa cttggaccaa gtctggagaa
     8641 ctcaggatag attggttgcg ataagtttcc tcaataacca ggtaggactc atataggaga
     8701 gcgtcagcca tttccagcaa gcgttccaag agacctttag gaagctgggt catcttttcc
     8761 cgtaaaaaaa gaagtaattc tgctgtagct tgggcatctg aaagggctgt gtgtgcgtgt
     8821 ttaagaggaa ttcctaattc tcgacacaaa atcggcaagc tatatttttc cagttcaggg
     8881 aaaaagacct gggccaattc gaccgtatca acacgagggt ttcttagctc atagccttca
     8941 aaaaataaat tttccgccaa gagattagca tcaaactgaa cattatgggc tacaaaaatc
     9001 ccatcctcca ccaagtcaaa tatttttctg gcaacttgcg aaaaatcagg tgcttgcgcc
     9061 agacgttggt ctgtcaatcc tgtcagttct ttgatatgag catccaaggg ttcatgtgga
     9121 ttgacatccg tcgtatagtg atcgacgatt tctccgtcct caatcacgac aattcccact
     9181 tggataattt tagccttact acctgtgcta gttgcctcta aatccaccac aacatagcga
     9241 ttaccaatcg ttttcattat aaaaaattat accaaaaaaa gggccatttg gcacctgcaa
     9301 acataggata attttcaaac tcaagaacac tacttttctt aaaaatccca tcgaatagag
     9361 cattctagcc tgctgatttt tttaaaatag tgaagaaata cgaaaaattg agagaagaaa
     9421 tgttttcatc ttccttctct caacgaatca tgtattttat ttaaccatgt caggatcgta
     9481 gtcataaaat cctgtatcaa ggaaacggtt tttagggtga agtttacgaa cttcttcatc
     9541 cagcaagaag gcttggtcat ggctaaagtt gccctcttga atcaagctac gcgcttggat
     9601 aaagagtttt gcaatctcaa caaagttctg accaggagtg tagagccctt ctagtttcca
     9661 gcgagtaaag ccatgctcca ccaattctgt taatttgatc atcaaatcaa ggtcattgtt
     9721 ggcaaagata tgggtcccat gattatcttc aaaaatggaa tagtggctct ctggatcact
     9781 tggctcagcc aagaagaggt cacgtttatg cgtcttttca tcatcgatat gtgtaaagtt
     9841 atagtagttt tgcaagagcg gacgtttaga atgatggatg acactagcac cgtaaaccaa
     9901 aacttcagca ggaatttcca aaatctctgg cattttgaaa agttcagctg atggaatttc
     9961 acgcgccaaa acagcctcag atgcaccagc cttttgtccc cagaagttaa tctgacgact
    10021 gctagttacc atggttgaag catcgtagat ggtcttaaat gaataaccat cgcggttgac
    10081 tacgtaaaag acgcctgcat ccccaatcgt aatatagtct gtcttgattt cttccaataa
    10141 gtctaagaaa ggcttgatac ggtccatcat atcttggtgc atgagagcat tgaccgcaac
    10201 gatcaattcc ttaccagcat catgaaccaa cttagcgatt tcacgtaatt ggtcataact
    10261 aaaggtcgtt ggcagacgaa ggccaaaatc tttctcaccg acatagatac ggtctacgcc
    10321 agcttcgagt agttgttcaa cttgttcaat actttcagca gttgctgtaa tgacaatctt
    10381 ttccataaga aaaattatac cacatttctc caaaatcagc catgctttga aaatgaaaag
    10441 ggactttatt ctttttgtaa cctttctgta ataattctct gccgaaaaaa tgataaaata
    10501 ggtatgtact gttaaggaga gaatcatgcc cgtaagaaaa ttacaatcct atgaggtaga
    10561 ctatcaagaa gaattaaacc agcagcttcc tcattaccaa gcttatacac ctgaagcgca
    10621 atctgatgcc aatctcaagg aaatcctatt ttttattaat atcgctgttt tttgtatctg
    10681 tattgctatc tttagtttta tctttttagc attaaaatta tcaactgctc ttgcctttgc
    10741 cgcagcaatc ggattcagct tacttgtttt aaaagttcaa cggtctatta tcaaacgaaa
    10801 acgtagaaga taaatccaaa atatcgcccc aattggagcg atatttttat tttttctttt
    10861 tagatggtgt ctgaatggca atcttcactt caaagattgt tcccttgggt ttattatctt
    10921 tgacagtaac agttcctttt agagcatcta caatttgctt ggctagggat aatcctaaac
    10981 caaaaccacc tttttgccgg gttctagcct tgtctactcg ataaaaacgg tcaaaaattt
    11041 tctttttatc ttctgtcgaa ataccgattc cattatcaga aacaagtaaa taaagattgc
    11101 gatcggtcgc cgagataaga aaatcaattt caccatcctc ctcagtatac ttgacggcat
    11161 tatcgaaaag aatggtcatc agttgtttca gaagaagctg atctgtgaca attgttcgat
    11221 ggatacgatt ttcaaaacgg aagacacgat tattttccga agcaatcatc tcatagtttg
    11281 tgaaagttgt attaaaaaag ctagttggaa cttctgcaag ctccggctta atcccatcat
    11341 ctctccgagc taagttcagc aagcttgtcg ttaaaaaacg catatttcgg acttcttcca
    11401 aactcgatgc aatgctttcg ctcacatcca taatggtagc ttctggctta cgaaaaaggg
    11461 tctctaagcg attttgcaaa actgcgagtg gagttcgtaa ctcatgactg gcattttcca
    11521 caaaagactg ttgcttctgc atactctcaa gcaggggcct aacactgacc ctagctagat
    11581 agagactggc aagtaaagac aaaatccaga aactagccat cacgaccaca atcaattgct
    11641 catgcttttg actagcctgc tccaactgac tggtattaat caagacagca gcatacttga
    11701 tattggttga aaccgaacta atattggtct ccatcaaaat cacacgatag atttcttcct
    11761 gcccatagct attaaaaacc tgaatctggt agatatgtcc tagttctttc ttttctaact
    11821 taatcttatc caagcccaaa aatcgatttc cagaaagaag ttgagtaaag tccttatcaa
    11881 agagaataac ttccgtattg gaactgacat taggttttat ttctacttta ctagcgtccg
    11941 ccctagcatt ttctaaatct ttaatctctt ctgttgccct atttatagcc agctgaataa
    12001 ctgcttgagg attttcactc agtccatgaa gcttatcgtc caccgaagta taaagactcg
    12061 aatgcatgac ttgtaaaata atcagagtca ttgtagaaaa aatcagggtg aagacaccga
    12121 agttgcggat aaaataacta aagtcatccg cataccatgt ttttttaagt ttactgaaca
    12181 tcttttaaaa gatacccaac actacgcaag gtttgcaaat tctctgcaaa agtggttccc
    12241 tttaatttct tacggacttt tgaaacatag acttcgacaa ccgaaatcgt tgtatcacta
    12301 tcaaatcccc atagacggtc aaaaatctgc gtcttaggca aaatcacatt ttgattttga
    12361 aggaaataaa ctagtaaatc gaactctttc cccagcaatt cgacaggagt atcttcaact
    12421 ttaacggtat tggttgataa attaaccacg atattcccat aagtcaaggt gttttcatta
    12481 aacttccctg aacgtttgag aagggcctga atccgcattt taagttcttc taggtagaaa
    12541 ggtttggtca gataatcatc cgctcccagt tcaaatccat gtcccttgtc atccaaactt
    12601 tccttggcag tcataatcag aactggtgtc gtaattccct tttcacgcaa ttcttttaag
    12661 acttggaaac catttttttc tggcaacatc aaatccagca aaatcaagtc atagacacca
    12721 ctctcagctt cgtagagacc ttcttctcca tcaaatacct gcataacatc cgcaaaatcg
    12781 tctaaaaagt caaatactga atttgacaga cctaggtcat cctcaaccaa taagattttt
    12841 atcatgagaa actcctcctt attaaaacta ttataccaaa tttgccttaa aaaaaactca
    12901 actctctgca ttttacatga gatagctgag ttttcttttt attttaggct tatttatgca
    12961 tttccgtatt gaagaacaac tgcttcgact gcagcttttt cacggctaat caagtcaaca
    13021 cgtgctgcaa tttccttgat tcccataccg atgttacggc taagagcaag gtcagaaagt
    13081 tgcggctcaa agaactcctt gtattccgcc aagcgttgct gagtcttaaa tacatgagca
    13141 ggaaggataa caaagctatc aaagctcata tctcctccaa gggctgcctt aatccaagcc
    13201 cagttttcac gcgcccaaga ccaagctgtt ttctgagttg cttgatgagc taggaattga
    13261 taataccaag cagacaagtc ctgtggtttg accacaaatt tgtccttcca agaagtaatc
    13321 aagttttgga tattatccgc atctgtactg tatgcaagag ctgctgccaa ctggcgttta
    13381 aagacagcat ctgttgcgtg agtataagta tcaagataaa gtgctaacaa gtctttagtc
    13441 tcatgatgtt tcatctcatt aatcagaact tgtgaacgaa tagctgctgg gagtcctgca
    13501 agattctcct tgtgtgttgc gaagatttgg ctagcgactt gactagcttc tgcatcattt
    13561 gagcgaatca tcatcgaaac agccagctga cgaaccaatt catcctcatc tgattctccg
    13621 tctttagctt caaaaccaag acggtcatag ttatgacgag ccaatttagc aaccagtcct
    13681 ttgaaggctg tttcagcatc cgttccttca tcaataaagc gctcaagggc tgaaatcact
    13741 tgagaaacag ctgaaaccac cagataagac tcttccttag caagtttatc aagaactgga
    13801 agcaagtctg cataagaaat gtgccctgcc tcagccaaca aacgacgttc ttgaacaatt
    13861 tgcagtttgc ttgtgttatc aagtgtctct agctcagcaa gaacagcttc taacaagtct
    13921 ccttgatagt cggtaatata gtgggcagta ttttcagtgt tgagacgaag agctccttca
    13981 ttttcagcaa gaagagctgc gtagccaggg atttcgatac tttcagtttc gagtgtatca
    14041 ggcaagcctt tccagttgct attgaggggc accacccaga gacggttctt gtcttcgttc
    14101 tcaccgatga agaattgttt ttgtgaaatc ttcaagacat cattttcaac tttgacagta
    14161 agaactgggt aaccaggctg ttccaaccaa gaatccatga aggctgcgac atcacgtcct
    14221 gacgcttgac caagggcatc ccaaaggtca ctaccaatgg tgttgctgta ttggtgtttt
    14281 tcaaagtagg cgtgcaaacc tttagcaaaa tcagcatctc ctagccaacg gcgaagcatg
    14341 tgcatgagac ggcttccttt ggcatagacg atagcgccgt caaagagtgt attgatttca
    14401 tctggatgtt taacttcgac gtggacagac tgaacgccat cagtagcgtc acgttcaaga
    14461 gcaagaggta ctccacctgt ttggaaatct tcaaagatat tccagcttgg ttcgatggta
    14521 tccacacaga cgtattccat catattagcg aaactttcat tgagccaaag gtcatcccac
    14581 catttcatag tcacgaggtt cccaaaccat tggtgagcca attcatgggc cacaacaagg
    14641 gcaacttgtt gacggctagc aaatgtagag ttctcatcga caaccaagta aacttcacgg
    14701 taggtcacaa gaccccagtt ttccatagca ccagctgaga agtcaggaag ggcgatgtgg
    14761 agagattgag gaattgggta cttaactcca tagtaatctt cgtaaaactc gatagagcga
    14821 acagcgatat ccagtgagaa atcaagattt gaaagtggat gtgctttggt tgagtagaca
    14881 cctaccaggg taccattttt agttttagcg gtcacccctt gcaaatcacc agcaacaaag
    14941 gccaacaagt aagaagacat gcgaggtgtt gtctcaaact tccagatacc tgtttcctta
    15001 cggttttcaa catcgatttc tggcatgttt gacaaggcca attcaccttc tgcttggtca
    15061 aagcgaagag agaggtcaaa agttgctttg gcttcaggct catccacaca cgggaaagct
    15121 tcacgcgcaa aatggctctc gaactgagta gacaagacct ccttcttgac tccatcaact
    15181 gtataataag aagggtaaat ccctgtcatg ttgtctgtaa ttttaccaga aaaggcaaga
    15241 accaattcaa cttgaccagc ctcagccaat tcgatatgaa gggcttcatt gtcatggtca
    15301 actgtaaatg gacgagcttg acctgcaact tctacagagg tgatttccaa gtctttttgg
    15361 tggagggaga tgcggtcact ctgtgcttga ccagtgatgg tcactttccc agaaaaagtc
    15421 ttggtctcac gactcaaatc taaaaataaa tcataatgtt caggaacaaa ttgcttaata
    15481 aaatgttcaa ctgcttgcat agttttctcc tattctaagt ttaagagctg ctgctcttct
    15541 tcaaacaaac ttattatatc atattttgct tgagaaaaaa ggattggaca gcgatttcca
    15601 aaactttctt ccttctaata gtctacagtg ggtagacctt gcgaaattct tctaaaacaa
    15661 ccttgctttc aggtgtaaaa gtcagcccta cttcacccaa acagtctgtg aaaaagtcct
    15721 catgaacctg gcgccaatag gcaagtgatt tgtctccctc accttcctta aaggcatgtt
    15781 gcgcagaaac ttgattgaag agttcaacag aaacctttgt aatttcgaca atgcagacag
    15841 cctgattttg actatctaaa atgacatcga aggtccctac ttggggaagt ggttcgtctt
    15901 ctagtacata gaggtcatag gctgatgctg ttgctgtctt ttctccttta aacaccaaat
    15961 ccgctaaaag gtctggttca actccaaaag cccaagcatc gatttcatct ccgatcaaag
    16021 gattgatttg cttgtattta ttccacattt cttgcggtgt catgggtact cctttgtaat
    16081 tttttacttt cttcttttat gtgtttaaga tgatctggat ggtcaatctc taaatcaaaa
    16141 atctctggaa tagaactgta gtggataatg cacttgatac ccaactgatt cattttttgt
    16201 atgaaagaag tattcagata gcctgctaca gcaaaattaa tcttgttctt tcttgcttta
    16261 tcctgcatat ctcttagcat atctaacatt attggacttt ccatatcatg ccattgactg
    16321 tttctcatag tcgcaaaaac aaaggaagtc aaatcattca ttccaactac aatctttgaa
    16381 atgcccgttt ccagtatcct atccaagtca aaatacgctg acggtaattc aatcatcgtt
    16441 ccgactttcc cagtaaagcc atactgacgc aatactgtaa tagcttgttt taattggtcg
    16501 gcatcattga caaaaggaaa gataagagat agattgggat tggtttgata aacttctgta
    16561 acgacatgtg cttcagcctg aaattcatcc aaacacgcca gtaaacgcct ggttcctcta
    16621 tagccaaaca agggatgccc ttcgtcaaaa aactctctag tccccactaa acaattggct
    16681 tctgtattcg ttaattcaga aaaacgatac caaacttcct tacctaagta aaaggagcaa
    16741 atagtatcaa gataatcttt cacaaattcc tgacaacttg ctaatatgat gttttgatta
    16801 agctctctca acaaatattc cccacgaatc atgccgacgt ggtgaaatag ttgaggataa
    16861 attttttcaa gaattttttc gccactaagg gcaagttgat ttctcatcat tcaccttcca
    16921 attcatgtaa gaagtcttgt ccagttctgg aaatcctaat aattcagact taaccttcaa
    16981 gactaatggc gatgcatttt cttctgtaat ctcttgaata tccatccaaa tatatccaag
    17041 tgaatcattc gcaccatcag acacagcttc cgaagtcgta acttgaggtg cactctcatt
    17101 catttcaaca tcatacaagg ccatgacatg gtgaaccata aaattggtta actcttctct
    17161 gacgaaaaca tcgtagattc gaggattaga gtagcttata acagtaaatc ccgtctcttc
    17221 cataacttct ctagtcagcg tttccgtcag tccttcacca agttgctgac tgcctccagg
    17281 tagatcatac cgatgttgat aagggcctct cgctttttca atgcagagta acttcccatt
    17341 ttctaagcaa acagcgtaga ctccaaagtg ttttttgatt tccatccaac tcctcctact
    17401 tcaaagacca gccaccatct attgtcaaga tttgtccttg catggcagat gcctttccac
    17461 tggccaaaaa gagactgact tctgccactt cctctggttc aatccagcgc ttgattggtg
    17521 tttcactagc cacccagtca gctaagccac ctggctcaaa atccgcagcg gtcatagccg
    17581 tcttgactgc tcctggagca atcccaaaga cctgaatccc agcttcagca tagtctagag
    17641 ccaactgctt ggtgaagcca gccaaggcat gcttggatga agtataggcg tgaccacctc
    17701 cacctgctag gctagaagca atggaacaca tattgatgat gattcccttt ttattttcca
    17761 gcatttgtgt caaataatac cgagtcaact caacaggagt catgtagtta atttcaaaaa
    17821 tctcttgaat ttcctgcgca gtctgttcca acagtggttt gtaatcatcc aaaactccag
    17881 cagtattaca caaaacatcc acctgagggc accagccaaa aataggttcc aagtccaagg
    17941 tcaaatctct ctgtaaaaaa tggaaatcac cctctaagag tggattttca ccttggtcaa
    18001 ctccataaac ttgaaagccc ttctctaaaa agagtcgagc ctgagccaat ccgatacctg
    18061 aactcactcc tgtaataagt acacgtttag tcatgcactt ctacccaatc cgttgccaaa
    18121 acatcacaag ctgtcgggct ccacatggaa aaaccttctc cttcgccaga aacgttgatt
    18181 aggaaataag gtgtcacttc aagtgcaagc ccgttttgtt caatggtgtc aaaaagttgg
    18241 acatagtttt ccgcacctcc ccaaccagtt cgtacatatt ttttcttagc ctttaagcca
    18301 ggtagaattt cttcaaatgt catgtttttc tcctttaatg tcaataattc tccccttcat
    18361 tataacaaaa aaaccgcttt aaaacggctt tttgactgtg atttatttac atcttcttct
    18421 acttacggca aattattccc tgcagcaaga taaatttcat accattcttt tcttgttaag
    18481 ctaaagtttg ccgctcggct aacttctctc aagtgcttag gatttgttgt acctacgact
    18541 gcctgcattt ttgctggata acgcaatatc caagaaatgg caatagttga agaggttact
    18601 ccatatttaa tagctaaacg atcaagtact tgatttaaag cttgaaattt ctcatttcca
    18661 acaaagttcc ctttaaaata cccgaattgc aagacagacc atgcttgaat gaccacatcg
    18721 tgtaatttgc aatattcaaa aatgctgcca tctcgcatag ctgcttgact atcttccata
    18781 ttaacatgaa aagctgattc aaatcctgga gtaaaagccg cactcaattg tagctgatta
    18841 acagctaacg gctgcttgac atctttttta agcaactcca tcatcatagg attttgatta
    18901 gaaactccaa aatctcgaac cttaccttgt ttataaagga gatcaaaggc ttctgctact
    18961 tggtcagatt ccatcaaagc atctggtcga tgaaggagca agctatctag atgatcaatc
    19021 ttcaatcttt gcaaaatacc gtctactgat tttataatat agtccttaga aaaatcaaaa
    19081 taggtaaatt cttcaatgcg aatgccacat ttggactgaa tccacatctt ttctcttaaa
    19141 tctggacgat tttttaggac aagacctaac agttcttcac aacgaccacg accataaata
    19201 tcagccaagt cgaaggcatt gattccaaca gaaagtgctg tttctacaag ctcttcaact
    19261 tcttttacag acttatcttt tattctcatc attccgagaa caatttctga taattctttg
    19321 tcatcttgac caagagttat gtatctcatc aaatttttct cctttaattt ctaacattct
    19381 tcccttcatt ataacaaaaa accgctttgc aacggctttt tgactatact tcactccatt
    19441 ttatcttctt aaacccacgg aacaagagaa aaatgccaat aaagaggaca gctaaaggaa
    19501 taacttttgt aaggaaaaca tttgaaattc ccatccactc ataataacgg agcagagaac
    19561 ccaccacaag atgggcaata atcatactga caaatggacg aaagaccgct tctttccaat
    19621 tccaaatacc gataactagc gaaatcgtaa agacagacaa actatcccag ggagccggaa
    19681 tataaaaggc tccttcttgt atgaagcttg ccattcctac atatcctaaa acaactagaa
    19741 gaactatagt cccaacaaca atgtaagtgc caattttcat tttaggagaa tcttggacta
    19801 aacttcttcg taaaattgtg gccacaagtc caaatccaat cagaaaaata agaagttgcc
    19861 ctaaaaatgt gagcaaattg actgttaaga gaggaccttt agaaaaatca cttagtagtt
    19921 gataataatg taataccgcc aggacaagaa ttggcgtcaa aagggactct ttgatagaac
    19981 tgcgaggtgc tcccttgaga atctctttca ttattttttt aggattctta cctagataat
    20041 cctctgcact catgccatct cgttctgctt ctgagaaatc tagcatcatc aaatagatct
    20101 gctctctgag atagtcttca tcatagagaa atccagcaag attaaaactt tcccacaact
    20161 cctcaaaata cttttgattc tcctcagaaa actcatgtag caaagcgctt gtttcttcgt
    20221 aatacttcat tttcttcatg gtttaacccc cattcttaat cccttctact ttttgactca
    20281 aatcgtccca ttgttgccaa aagactgaga cacgctcttc tccttctttc attaatgaaa
    20341 aatacttccg atctggacca tctggcgacg ggcgcatgtc gcctcttatc cattgatttt
    20401 tttctaactt ttgcaacaaa ggataaatag ttcctggaac gatagtatca aatccagcct
    20461 ctcgcaaagt ctgaaccaac tcataaccat accgctcttt ttgaccaatc atatccaaga
    20521 cacaaccttc aagaacacct tttaatagct gagtttcttt catcacttct cccttctaat
    20581 ctattttgta atacctacta gtaacttcac ctatagtata ttacttctac actagtttgt
    20641 aaagcataat agttaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccctacc
    20701 gtatgtatgg ttactgactt cgtcagtttc atctacaacc tcaaaacagt gttttgagct
    20761 gacttcgtca gtttcatcta caacctcaaa aacatgtttt gagctgactt cgtcagttct
    20821 atctacaacc tcaaagcagt gttttgagca acctgcggct agcttcctag tttgctcttt
    20881 gattttcatt gagtataaat aaaaaaacag aactagcctg aactagtcct gtctactttt
    20941 acccaatcac acttccattt ggtacagctg gatcaactgt gagaagggtt aatttgccat
    21001 catgttcagc tgagagaatc ataccctggc tgacatattt tttcatcatt ttacgtggtt
    21061 tgaggttagc aacgatttga actttcttgc cgaccaattc ttgttcattt ggatagtatt
    21121 ttgcaattcc tgaaagaatc tgacgatctt ctccatcacc agcatccaag cggaattgaa
    21181 gcaacttatc tgaaccttct actttagaca cttctttgac ttctgcgaca cggatttcaa
    21241 ccttgtcaaa gtcttcaaac ttgatttcat ccttgtttag tttgagctca acttcgtccg
    21301 gattccattc tttttcgact gctggtttat tgccttccat ttgttccttg atataggcga
    21361 tttcttcttc catatttaga cgtggaaaga taggtgttcc tttggcaact acagtcacat
    21421 ctgctgggaa gtcagccaaa ctcaagtttt caagactaga aacttcttcc aaaccaagtt
    21481 gagtcaaaac tgcacgacta gtttccatca taaatggttc aatcaagtga gcaactacac
    21541 gaatgctggc tgccaagtgg ctcatgacac ttgccaattg gtcacgaaga gcttcatcct
    21601 tggccaagac ccatggtgcg gtctcatcga tgtatttatt ggtacgagag atcagagtcc
    21661 agactgcttc aagcgcacgt ggatagtcaa ctgcttccat gtgtgtatgg aagtctgcga
    21721 ttgattgttc tgcaacctca gcaagaacat gatcaaattc agtcacacct tctacatagg
    21781 cagggatttg tccatcaaag tacttattaa tcatggaaac cgtacggtta aggaggttcc
    21841 caaggtcatt agccaattca tagttgatac ggccgacata gtcttcagga gtaaaggttc
    21901 cgtctgaacc aactggaagg ttacgcatga ggtagtaacg aagtggatct agtccataac
    21961 gctctaccaa catttcaggg taaacgacat tcccttttga cttagacatt tttccgtctt
    22021 tcatgacaaa ccaaccatgg gcaatcaaac gatcaggtaa tttaacatcc aacatcataa
    22081 gaaggattgg ccagtagata gagtggaagc gaaggatatc ttttcctacc atatggaaga
    22141 ctgttccatt ccagaacttg tcaaagttac catgttcgtc ttgagcgtag ccaagagctg
    22201 tcgcatagtt aagaagggca tcaatccaaa cgtagacaac gtgttttgga tttgatggga
    22261 caggcactcc ccatgtaaag gttgtacgag ataccgccaa atcttccaag cctggctcga
    22321 tgaagttgcg tagcatttca ttaaggcgac catctggcgt gataaattca ggatgagctt
    22381 tgaaaaattc gaccaaacgg tcttggtatt tgctaaggcg aaggaagtat gattcttcag
    22441 aaacccattc aacctcatga cctgatggag caataccacc agtcacattt ccagcttcat
    22501 cacggaaaac ttctgccagc tggctttctg taaagaattc ttcgtctgat actgaatacc
    22561 aaccagagta ttcacccaag tagatatcat cttgagcaag taagcgttca aagacttgtg
    22621 cgacaacttt ttcatggtag tcatcagttg tacggataaa tttatcgtat gagatatcta
    22681 gtaattgcca gagttcttta actccaaccg ccattccatc aacataggct tgaggtgtaa
    22741 taccagcttc ttccgctttc tgctggattt tctgaccatg ttcatcaaga cctgtcagat
    22801 aaaatacatc gtagcccatc aggcgtttgt aacgtgctag gacatcacat gcgatagttg
    22861 tgtaggcaga accgatatga agtttcccag atggatagta aatcggcgtt gtaatataaa
    22921 aatttttttc agacataatt tttcctttcc aggcaaatga aacctgtttt tctaacactt
    22981 cattatatca catttttaat gaatttcgat agggaaatcc atacaaaaac aagatagacg
    23041 agtgtccatc ttgttgatct cattcataac gaagggcttc aattggatca agtttcgatg
    23101 ccttgttggc tggcaagact ccaaaaatca taccaacact agccgaaact gcaagactaa
    23161 atagggcaac tgggattgat actccaactt ctataccttc tattaaacct tgcagtaaca
    23221 aacctgctaa ggcagttaaa ccacttgcaa ttgtcaagcc aattaagcca cctaacaagg
    23281 tcaaaatcat ggattcaatc aaaaactgaa ttaaaatatt ggcacgtgtt gcacccaaag
    23341 ccttacgaag accaatctca cgagtgcgct ctgtcaccga aaccagcatg atgttcatga
    23401 caccagttcc tccaacaaag agagaaatcc ctgcgatgga actaataatc gtcgtcataa
    23461 aactaaacga ttgttgaatt tctgcaaata caacggactc atctgccacc tggtattctc
    23521 cctgttgtaa gcctgcaagc tctgtcattt ttcgtgccag ttctggaccc agagttgggg
    23581 ttaaactggt atcattcact cgaaagacaa tattagctat ttcatctaca ttaaaattcg
    23641 cagcaaggga gatattggta gtaataggca agccaccaaa cccatatatt tttgatcttt
    23701 tagcctccgg actagtataa accccaatga cccggtaact aaatccattg acttctacaa
    23761 ccttgttaat agcctcttga ggagattcaa ataaactaat ggacaattcc tcatctagca
    23821 aaatgacact tgcaaactct ttgaaatctt gctctctcag actacgacct gcaataattt
    23881 cattcttaac agcgtccatg taagttctgt ttccacctgt caaattagca ttctcaacct
    23941 ttttatcttg ataggtcaag atggcattcg ttgaattggt tacatagtaa ctatccactc
    24001 ccttcagttt agctgcctct tgaacccagg attcttgcgg ttttggcggt tcaacaggaa
    24061 cttcctcttc ctttccagaa accgtaaaag ctgattgttt ctgagtaaaa gacccatctt
    24121 tacttttttt aggagagaaa aagacgctaa tatttttctg aaatttagtc atatctttat
    24181 tgacttgacg agatagggaa tcacccaaag ccataatcac aacaactgat gaaacaccga
    24241 taataatccc aatcatagta agcaaagaac gcatcttgtg agccatgata gatgaaaagg
    24301 caaatttcag attctgcatc ttagttttcc tcctttccta actgagcact gtcagacgaa
    24361 atgaccccat cccgaatgac aatctgacgt ttggcatagg cagcaatctc aggctcatgc
    24421 gttaccatga taatggtttt tccttcttta ttcaaatcaa ccaataattg cataatttgg
    24481 ttacctgttt tggtatccaa ggctcctgtc ggttcatccg ctaggataat agaaggattg
    24541 tttaccaagg cacgcgcaat ggctacacgt tgcttttgac caccagataa ttctgaaggt
    24601 aaatggtgac tacgttctgt caattcaacc ttgtctaaat attcctcagc caacttgcga
    24661 cgttttgaag acgaaactcc tgcgtaaatc aagggcaatt ctacattttg cagagcattg
    24721 agcttcgata gaagaaagaa ctgctgaaag acaaaaccga tttgttggtt acggacctta
    24781 gccagttgtt tttcaccaag cccagccact tcttgacctt caagataata ttctccactg
    24841 gttggtgtat ccaacatgcc aatcgtattc atcagagtgg acttaccaga cccagatggt
    24901 cccatgatgg ctacaaattc accctcattc acttctagat tgatattttt gagaacctgc
    24961 agttcttggt caccattacg gtagcttctg aagatatttt ttagactaat tagttgcttc
    25021 atcagccttc acctcttttc cttcttccaa ggaagatgtt ggattactga tgaccttagc
    25081 accatttgtc aaaccagaag tgatttcttg attttctgcg tcagcatttc ccaatgaaac
    25141 ctcaactttt ttagcctttt gttgttcatc cacaatccag acataatttt tactatcatc
    25201 cattactaga ctgctaacag gaacaagaat agccttagtt ttgcttttaa cctcaatgtt
    25261 gacagaaaaa ccttgtttca aatcaccaac ctcgcctgtc acatcaatag tataagggta
    25321 tttagaacct gtattattcc cggctgctgg actagctgct tcaccattgt ttttaggata
    25381 gtcagaaata tagcttaatt tcccagtcca ttttttatca ggatacactt tagaagtaaa
    25441 gcttacttct tgacctacag aaaggttggc tagattgtac tcagacaatt ctcccttgac
    25501 ttgtaaattt tcattgctga caatatgaac cataacttga ctcgcccctg ttggagattt
    25561 agaaacattg ctattgactt cgaccacagt tccctctagg gtactgagaa cagttgttgc
    25621 atccaattga ctttgagcct tgcttaattg cgccgcagca tctgcacgcg catcacgggc
    25681 atcacccaat tgagcgtcaa tagaagcaac agaatttcca gccactggag ttgggctttg
    25741 caccgttgca tcttctcctc ctactggcgc tggtaactgt ggagccggag ctgaagcggc
    25801 ttcatttcgt gcttgattga gttcattgat atgacgatct gccctagcta ctgctcgact
    25861 agctgaatca taggccgcct gcgcttctga actactgtac ttgactaaag cctgcccttc
    25921 gctgacctta tcgcccacag aaacaaggat ttcatctaaa tcacccttac tagcatcaaa
    25981 ataaacatat tgttcatttt ttgctgttac tgtccctgac aataaaacag aggaggccac
    26041 gcttccttcc ttggcaacaa caagatgagt aggctcatct tttagagcag tctgagaagg
    26101 ttgtctaaag agtaaaatcc ccccagcacc caatacaact acactcgcag caccgattgc
    26161 tgcatacagt tgccactttt tagctttacc attctttttc ttcataatga aactcctttt
    26221 cttttttaca atactttgct attataccaa atttccctcc agcaaacaat acagttcagg
    26281 attaaacaat cgttcggaat tttgcttttc tattgtacta gatatataat acactatctt
    26341 gacttatttg gcaagctttt ttgcaatttt ttgtgcgtag cagatttttg caatcaaatc
    26401 aaaaaaagaa taaaatataa ctatcaaaaa agacgctcta ctatttaaaa gattacaaag
    26461 gagttttcaa tgagagaata tgatatcatt gctatcggtg gaggtagcgg aggaatcgct
    26521 accatgaacc gtgctggtga acatggagcc aaagcagccg ttattgagga aaagaaatta
    26581 ggtggaacct gtgtcaacgt cggttgtgtt cctaaaaaaa tcatgtggta cggggcacaa
    26641 atcgctgaga ctttccatca atttggagaa gactacggct ttaagactac tgatcttaac
    26701 tttgactttg caaccctacg tcgcaatcgt gaatcctaca ttgatcgcgc tcgttcttct
    26761 tatgatggca gttttaaacg caacggtgta gacttgattg aaggtcatgc tgaatttgta
    26821 gattctcata ctgtaagcgt aaatggtgaa ctgattcgtg ctaaacatat cgtgattgct
    26881 acaggtgccc atccaagtat tcctaatatt cctggtgctg agctaggtgg ctcttctgat
    26941 gatgtatttg cctgggaaga acttccagag tcagttgcca ttctaggcgc tggttatatc
    27001 gccgttgaat tagctggcgt actccacact tttggtgtca agacagatct ctttgttcgc
    27061 cgcgatcgtc ctttacgtgg ttttgattcc tacatcgttg aaggtttggt caaggaaatg
    27121 gaaagaacaa acttaccact tcacactcac aaagtccctg tcaagttaga aaaaactact
    27181 gacggcatta ccattcattt cgaagatggt actagtcaca cagctagcca agttatctgg
    27241 gctacaggtc gccgtccaaa cgttaagggc ttgcaacttg aaaaagctgg agtgactctg
    27301 aacgaacgtg gctttatcca agtggatgaa taccaaaata ctgttgttga gggaatctat
    27361 gctctaggtg atgtaacggg cgagaaagaa ctgactccag ttgcaatcaa ggccggacgt
    27421 accctatctg aacgtctctt taacggaaaa actactgcaa aaatggatta ctcaactatt
    27481 ccaactgttg tcttttcaca ccctgctatc ggaactgttg gtttgacaga agagcaagct
    27541 attaaagaat acggtcaaga ccaaatcaag gtttataaat caagctttgc atctatgtac
    27601 tctgcttgca ctcgcaaccg tcaagaatcc cgtttcaaac tcataacagc tggttcagaa
    27661 gaaaaagttg tcggacttca tggaattggc tacggcgttg atgaaatgat tcagggattt
    27721 gccgttgcta tcaaaatggg agcaaccaag gctgactttg atgcaactgt ggcaattcac
    27781 ccaactgcat ctgaagaatt tgtaaccatg cgttaatcga aacaaaagaa gctgatataa
    27841 atatgtctgc ttctttttta atgattttcg aatcaacaaa aaaattatcc aacttgacta
    27901 gtcacgaaaa tcggctgtta cagtttttgt taccttgttt ttaaaaaatg gttgacatcg
    27961 actcctatat gagtataata gttactatac attagaaaag aggttaacta ttttgaaaaa
    28021 agctcacgtt tatgctatcc ctgctattgg ggctgctctc attgctgttt tggcacaaat
    28081 cagtcttcca attggacctg ttcccttcac tctgcaaaac tttgcaatcg gcttgattgc
    28141 tactgtcttt agaccgagag aggctgtact ttctgctgga ctctatcttc ttctaggtgc
    28201 tatcggtctt cctgtctttg caggaggtgg agctggtttt caggctttag ttggccctac
    28261 tgcaggctat ctttggtttt atctcgttta ctctggactt acttcctctc taaccaacag
    28321 caagagtggt gttgttaaga tttttcttgc aaacctcttg ggtgatgccc ttgtctttgt
    28381 cggcgggatt ctcagcttgc atttcctagc tggaatggca tttgaaaaag ctcttgttgt
    28441 gggggttctt ccctttatca ttccagacct tggcaaactt ctggctatta gttttattag
    28501 ccgtccccta cttcaacgcc ttaaaaatca ggcttacttt actaactaaa aaaggatacc
    28561 gagttatcat gactcaatat cctttttttt attttgaaaa cttatactca atgaaaatca
    28621 aagagcaaac taggaagcta gccgcaggct gctcaaaaca ctgttttgag gttgtggatg
    28681 aaactgacga agtcagtaac catacatacg gcaaggcaaa gctgatgcgg tttgaagaga
    28741 ttttcgaaga gtattagttg cctttaaagg catccaccat cgtttgaaat tcttcatttg
    28801 agagagtaat ccctttgccc attttagtat ggtttggact ccaagcacga atatcaaact
    28861 ttgcaggggc accattaaag ctcacacggt taatttcctt ggtccaacct ttttcgtttt
    28921 cagaaagagt caacaagtgc tcttcgattt caaatgtaaa ttctgccatt ttcttctcct
    28981 tttttagttt cattagttta ttcgtaaaat cttgtagatt ttaggaaaat tttatataat
    29041 attgatataa aataagggag gccaatatga gacataaatt ccagcaagtt ctagataaaa
    29101 tacatgattt tttaaatgga catgaccaac ctgaccagac tgaaaccaac tcccttacag
    29161 ccactattga agaggctatc cagaaacaaa ccgctgttca ccttatcttg tctgagacaa
    29221 gttttacagg tgatatcatc aaatatgatc agcaaggcca gcaaattatc gtgaaaaatt
    29281 ttgccaaaaa tgtgagccgg attatccgta taagcgatat tcaacgcctg cgatttgtcc
    29341 cctcaactgt ccaaacagcc caaaaaaata gatttaagaa agagtgagat gtagttgctt
    29401 catcccactc ttttttctta gcgaatttgt tcaaaatgta aatgaactgc aatatgatct
    29461 ccataaccac ttctttccaa gtcacgttgt aaacgatagg aaatgtagtg ttctgcaata
    29521 gtaatgtaac ctgcgcccaa taaacgatgt tcaaccatag attgaatcat actgatagtc
    29581 gcacgttcca ccttggcttc ttgtaaatcc aaaactacct tcttagtgac ttgagcaaga
    29641 ttttgacgca aatcatctgt caaaacataa acagtttggg ctgccttcaa gatggcttgg
    29701 taaatcttat ctggattaaa ttcagcaatt tcgccattac gtttgattac ttgcataggt
    29761 ttctccttta ttctttgttt tctttgattt ctgccagcat tttttcttct tctactgtca
    29821 gttgataatg ttcaagtaaa tccggtctgc gctcgtaggt tttctttaaa ctctcgtaca
    29881 atcgccactg acgaatcttt tcatggtggc cactcatcaa tacatctggc acgaccatgc
    29941 ctcgataatc atagggacgt gtgtactgag gatattctaa aagacctgaa gaaaaactat
    30001 catcttggtg gctagactcc ttgccaatca cttctggaat caggcgaact gtagcatcaa
    30061 tcatggtcat agctgccaat tctccaccag tgaggacata gtcgcctagg gaaatctcat
    30121 ctgttaccaa ggtcttaatg cgctcatcat aaccctcata gtgcccacag ataaagatta
    30181 gctcttcctc ttgagccaaa tcttcagcat aagcctgatc aaactgcttt ccagcaggat
    30241 cgaggagaat aacgcgcgga tttttctttt caatagcatc aaaggaatcg aaaataggtt
    30301 gtgctctgag caacatgccc tgaccgcctc cgtagggctc atcatctaca tgacgggcct
    30361 tttcagcatt ttctcgaaaa ttatgatact ggatatccaa gagccctttt tctcgagcct
    30421 ttccaacgat tgagtgctcc agtggagaaa acatctctgg aaagagggtt aaaatatcaa
    30481 tcttcatcgt ctaacccttc taagatttcc acatcgaccc gtttatttgg aatatcaaca
    30541 ttgagaacca ctggtgggat ataaggtaaa agcaaatcac gtttgccttt tcgtttgacc
    30601 acccagacat cattagcacc tggttgcagg atttccttga tggttccaac caagctatca
    30661 ccctcataga cttccaaacc gataatctcg tgatagtaaa attcaccatc gtctaggtca
    30721 ttcaaatctt cctcagcgac cttgagactg tatcccttgt acttttcgat agtattgata
    30781 tggtacatat ctttgaattt aataatgtca aagttcttct gtttacggtg gctagcgatg
    30841 gtcactgttt ggacaaactg atctttttca tcaaacaaag ccagctcagc tcctttttta
    30901 aaccgttctt ctgcaaaatc cgtcacagac aagactcgca tctcaccctg taatccctgc
    30961 gtattaacga ttttcccaac attaaagtag ttcatcttgt ctcctgtaat ctcctttttt
    31021 ccatcttatt ctgacaattc tcgaataata gccgcaattt tttccgattc tgaccattgt
    31081 aaataatggt gattccctcc taaaatgagt ttagtattgg aagtccaata ttctgattct
    31141 ctgtactctt tttctctata aggctgacaa aaaacaaata caggaatatg agcttctata
    31201 gatacatcct caaaatcttc ctcagtaatc tctccagata tctgaaattc tggatcttga
    31261 ttttccaact ctaagccttt ttcttgcatt aattcccaga tttttttatt cgtttcagga
    31321 ctaaatgttg cttgagttaa attcttcaaa taaagttcag gtccatactc gtcaatcagc
    31381 ctcatctgct cttccatttc tggataagga ttttctgaaa aatcagcaaa catgactttt
    31441 ttagttgtcg gttcaattgc tactaaagtc tgacacttaa ttggtttctc gagtaatttg
    31501 caagctaaaa ttccactcca actatgtgca caaagtatat attcagaaat ccctaattct
    31561 tcaagtactt cataaaccac atctgcaaga ttatctagat tttttccagc ttggtcatga
    31621 atcggactcc tacctgtgtt cggaaaatca attgtcaaat aaccaattgt aggaggaggt
    31681 ttttcaagta taagtgaaaa attttcataa cttggtagca aacctgctcc gtttagacaa
    31741 actagcactt tcttttgctt ttgataagta acagagaggc taccaatttc tgtagatact
    31801 tcaaacctct tcataaagaa atccactcat tctatataat gaattattaa aaatccttat
    31861 cctttatttt atcacgttcc aaggattttc tcaagttgga ggaaggggac aacatctcta
    31921 ctttcccttc aagaatcctt ccaaatcatg tttatgttgg taattaacga ctgcggtttt
    31981 gtctttctca aagacagtct tggtaaggtc aatatgcttg atagcagcaa tagcgacggt
    32041 gtagtaaatg atatcagcca gttctctggc aagttcctcg ttcgaatcct atcccttctt
    32101 ttcgaccaga gcgcctattc aaaacctcgg ctacttctcc gacttcctcc actaacttca
    32161 taaagagacc ttcatcagtc cgagactgct gttaatgttc gagtaagtag tcttggaatt
    32221 gcctaaacgt tcaatctttt atagtatatt gaaactagaa tagtacacct ttacttctaa
    32281 aacattgtta gaaatcgatt tgactgtcct gatcgatttg tcctgttctt gtttcatttt
    32341 actatatctt ctattccaca caaaaaagcg agacatccgt cccgcccttc ttatttttcg
    32401 tcaataacga ttcttacttt tttgtattca gttgggacag agtagacaat cgttcttatc
    32461 gcagaaatag tgcgaccctt acgaccgatt acacgaccca catcgctttg atcaagattc
    32521 aaatgatatt ccaaaaattc tggtgtatcc tcaatcttga tagttaaggc atctggttgt
    32581 gaaattaagg gtttcacaat cgcaataatg agattttcaa tcgtatccat ctgtcaacct
    32641 actttaaact tattttgaaa atttagaatc gtggaatttt ttcaatacgc cttcttttga
    32701 aaggatgtta cgtactgtgt ctgaaggttg agctccatta gccaaccatg caagaacgcg
    32761 gtcttctttc aaagttactt ggttttcagc aacaagtggg ttgtaagttc caactgtttc
    32821 gatgaaacgt ccgtcacgtg gtgaacgtga atctgctacg ttgatacggt agaaaggttt
    32881 tttcttagaa cccatacgag tcaaacggat tttaactgcc atttttaaag tctcatttct
    32941 ttaatttttt atttcggtga aatagctgag ctatttagca catgttctat tatagcagat
    33001 ttctggcatg tgtcaagaaa aaaacttgac agactataaa tttcttaaag tatttagaaa
    33061 tttgttagaa taggaaataa atgtttgaaa gatgctatcc gtgaatacta ttttagaaaa
    33121 attttataaa gaacaccaag tcaaaccctt catatcgcct gaacgagagt tggatacttg
    33181 gcttctaagt cccaagcccg ttcccaagcg aaatatggac ttattagtag atgattcact
    33241 agcaggagat atcattttac tatggagaat ccagtttggt acttttacca ctgaaacatg
    33301 attttaaaaa ctcccattcg aatatgattc aaaattcgct tagaatcaat gttttcccac
    33361 tttttcaaaa aataaatttt catctaattt aaataacttt caattaagtg tgaattttgc
    33421 ttaaaatcat taaaaaacac cccatggtgt gaaccatgaa gtgttgtaaa tgctgtgttg
    33481 tagctagttc ttagcgttta gagaactggc tagctttacg agctttctta agatctggtt
    33541 tccaaaatac tttgagtaca cttatggtat tgatgcccct aaacatctaa aaactctggt
    33601 agaaaaaggg tatgctcttg tcgaaacttc ttttgactca cttgaccatc taaataatac
    33661 catgaaaaag aatatcctga agaagaaggg agttactgga ctttctaaaa tgaaatcttg
    33721 cgacctggat caagcccttc atgagcattt ttcagaagaa gaattagctg gtcactttca
    33781 tgtccttcta tggacttttt tacaatggca ttgctatcac acccaatacc tatctaagcg
    33841 cctggttcgt aaactttatt gcagctcttc ctctaaattt cctaattgtt gaaccaattg
    33901 cccgttttat actaagttct tttcagaaac catttactgg ggaagaagtt gaagattttc
    33961 aagatgatga tgaaatccca actattatct aagccagttc tgtaaactac taatatttga
    34021 aatccacttc cttttagggt acaatggtat aaatgaattt ttgagaggat cagaatgaaa
    34081 aaactagcaa cccttctttt actgtctact gtagccctag ctgggtgtag cagcgtccaa
    34141 cgcagtctgc gtggtgatga ttatgttgat tccagtcttg ctgctgaaga aagttccaaa
    34201 gtagctgccc aatctgccaa ggagttaaac gatgctttaa caaacgaaaa cgccaatttc
    34261 ccacaactat ctaaggaagt tgctgaagat gaagccgaag tgattctcca cacaagccaa
    34321 ggtgatattc gcattaaact cttccctaaa ctcgctcctc tagcggttga aaatttcctc
    34381 actcacgcca aagaaggcta ctataacggt attaccttcc accgtgtcat cgatggcttt
    34441 atggtccaaa ctggagatcc aaaaggggac ggtacaggtg gtcagtccat ctggcatgac
    34501 aaggataaga ctaaagacaa aggaactggt ttcaagaacg agattactcc ttatttgtat
    34561 aacatccgcg gtgctcttgc tatggctaat actggtcaac caaacaccaa tggcagccag
    34621 ttcttcatca accaaaactc tacagatacc tcttctaaac tccctacaag caagtatcca
    34681 cagaaaatta tcgaagccta caaagaaggt ggaaacccta gtctagatgg caaacaccca
    34741 gtctttggtc aagtgattga cggtatggat gttgtggata agattgctaa ggccgaaaaa
    34801 gatgaaaaag acaagccaac tactgctatc acaatcgaca gcatcgaagt ggtgaaagac
    34861 tacgatttta aatcttaaaa accaaaaaaa tacagtatcc acattcggta ctgtatttct
    34921 tttactctca ttcttaagtt aaattattaa aatcccatat ttggtctatc cagccttcat
    34981 aaaagtctgg ctcgtggcag accataagga tagatcccct atattctttg agagcgcgtt
    35041 tgagctcatc ctttgcatcc acatccaaat ggttggtcgg ctcgtccagc actaaaacgt
    35101 tgttttcacg attcatcaag agacagaaac gaaccttggc ttgctctccc cctgataata
    35161 cttgaatctg gctttcaata tgtttggttg tcaaaccaca acgggcaagg gctgcacgga
    35221 cttctgcttg attaagggca ggaaaggcat tccagacagc ttcaagagga gtttggcgat
    35281 taccaccttc tacttcctgc tcaaaataac caagttctaa ataatctcca cgctccactt
    35341 ccccagcgat tggcgagata atgcctaaga gactcttcaa gagagttgtt tttccaatac
    35401 cattagcacc aataatcgca accttttgat tgcgttcgaa ggtaagattt aaaggcttag
    35461 taagaggacg gtcgtaacca atttgcaagt tcttggcttg gaagataaag cgccctggtg
    35521 tacgagctgg tttgaaatca aaggatggtt ttggtttctc actttggagt tcgataatat
    35581 ccatcttatc caatttcttt tgacgagaca tagccatatt acgagttgca acacgggctt
    35641 tattacgagc cacaaagtcc ttgaggtctg caatctcttt ctgctggcgt tcgtaggctg
    35701 cctctagctg agatttcttc atagcataaa cttcttggaa ctggtagtag tcaccagagt
    35761 aacgcgtcag ctgttgattt tccacatgat agacaatatt aataacgtca ttgaggaatg
    35821 gaatatcgtg cgaaatgaga acaaaggcat tctcatagtt ttggagatag cgcttgagcc
    35881 aatcaatatg ctcagcatcc aagtagttgg tcggctcgtc caacagcaag atatcaggct
    35941 tttcaaggag aagttttgcc aaaagcacct tggttctttg cccacctgac aaagaagtta
    36001 catccgtatc catgccaaag tccataacac caagagcacg cgctacttcg tcaatcttag
    36061 catccaaggt atagaaatca cgactctcca gacggtcttg aagttctcct acttcttcca
    36121 tgagagcatc aacatccgcg ccgtcttcag ccattttcat atagaggtca ttgatacgag
    36181 cttcagcttt gaaaagctca tcaaaagccg tacggagaac atcacgcacc gactgtcttt
    36241 cagcaaggac agagtgctga tccaagtaac cagccgtcac atatttggac cactcaacct
    36301 ttccttcatc tggcagcatt ttaccagtca cgatactcat aaaggttgat tttccttcac
    36361 cattggcacc gaccaggccg atatgttctc ccttgaggag acggaaggac acatcttcaa
    36421 aaattgcacg gtcaccaaaa ccgtgactca gatttttaac ttctaaaata ctcattttaa
    36481 ttccttatct tgtttttatg taatcgttta taaaggagcc aagccagata gccacccaaa
    36541 gtattggtcc acaaatcatc aatctcaaag acgcgattga aatcaaagaa aaagtccaag
    36601 attaattgcg tacactcgat tccaagactc acaagaaaac taaaaagaag gacctttttt
    36661 gttttccgca aatttggaaa tagataaagg agttggaaaa tcagaggaaa aaacaagaag
    36721 acattgagga cattttgtaa aaaaatccaa cataattgtc caatgtcact cacttcgccc
    36781 agtttccaga gagaattgaa aggagtcaaa agaaaaacca ggcgtccaag atgctgaata
    36841 cctggagttc ccactcccac ggtagattgt tcttgaggag taaagcaaaa acagacaatg
    36901 caaatgctat agaaaatgac tccccagacc aaaatatgat tataagtctt cttcatcatt
    36961 aaggatttac cgctgcgact gccttctggc ggtcacgttt cattgtgtta gagcgcaatt
    37021 gtccacaagc tgcgtcaata tctgtaccat gctcttgacg aaccacacag ttgacccctt
    37081 ttttcttaag cgtatcatag aaagccaaca cgcgctcttt gggactacgg ctatattggt
    37141 catgctcact aactgggtta taaggaatca agtttacata agacaatttc ttgatgttct
    37201 tgagcaattc agccaattcc aaggcttgtt ctacaccgtc gttgacttca ttaagcatga
    37261 tatattcaaa ggttacacga cggtttgttg tctcaatgta gtattcaata gcagcaaaga
    37321 gtttttcaat cggaaaggca cggttaatct tcatgatact tgaacgaagt tcattgttgg
    37381 gtgcgtgaag agacacggca agattgacct gaaccccttc atcagcaaag tcacgaattt
    37441 tatgagccaa acctgaggtt gaaaccatga tgtgacgagc accgatagcc attcctttat
    37501 catcattgat agtacgaaag aaattcaaga cattgttgta attatcaaag ggctcaccga
    37561 ttcccatgac aacgatatgg ctgacgcgtt catcctgacc acgctcatca aagtatttct
    37621 gaaccagcat gatttgcgct acgatttcac cgttattgag gtcacgttgc ttcttaatca
    37681 aaccagaggc acagaaggta caaccgatat tacagccgac ctgagtggtc acacagacag
    37741 ataaaccata gtgttgacgc atgagtacag tctcaattaa cataccgtcg ggcaattcaa
    37801 agagatattt gactgtacca tcagcagact cttgcacaat acgttgtttc aagggattga
    37861 ccacaaactg gtcattgagc ttagcaatca aatccttgga aaggttggtc atttcttcaa
    37921 atgactgcac acgtttacgg tagagccatt cccagatttg atctgcacgg aatttctttt
    37981 ctccctgctc caatacccat tcctgcatgg tttgatgtgc caaactatga attgagggtt
    38041 tcatttcttc tccttattct ctactcactt ctgacgaatg acaaaatgac gttgtccctt
    38101 gtcctctttc tgagaatgct ggtctttctg acgacgtcta ttcttcttat ctgcattcga
    38161 ctttcgttta gtttgagtcg gtttctttcc ttttctagaa ggtgtttctt cttccgtctt
    38221 acgcattttc ttgtcaaatg atgctcgctt aggggcttca ttttctaaga caaaataggc
    38281 acaaccataa ctacaatact ctaaaaggta gtcttgtaaa cgactgattt tttcaagttt
    38341 ttcttctgtt cggtcatcct tgtaaaaacc tcgtaggcga agctgttcgt tgctccagtc
    38401 ccccacgata taatcaaact tggttaatac ttctgaaaaa cgctgattaa aagtcgtcac
    38461 atcaaaggca tccttgatat tttcaaccaa ggaaaaagct atcccttccg tttcgacctt
    38521 gtccccgtgt aaatggaact ccggaccagg aaacttgtta tagttgtata attcaggtgc
    38581 aatttctttt cgcatagata tccttttttc acgattactt aatactttat tctaccataa
    38641 tttctagcag ttagcacgtt tctcataaaa atgaaaaaag tctaacgatt ttgtcagacc
    38701 agaatcttat aacctaaaaa agagaagaac aattcttccc tccaactatc attatttagc
    38761 agctgcgtac aattcatcta ctttattcca gttgattact gaaaagaaag ctttgatgta
    38821 gtcaggacgc acgttgcggt atttcacgta gtaagcatgt tcccaaacgt ccaagcccaa
    38881 gattggtttt ttaccttctg agattggtgt gtcttggttt gctgttgaag tcacttcaag
    38941 ttttccttct ttgttgacaa ccaaccatgc ccaacctgaa ccaaaacgag ttgttgctgc
    39001 tgcagtgaag gctgcttgga attcttcaaa tgaaccaaat gttgcatcga ttgctgctgc
    39061 cagttctgct gaaggagctg ttttctcggg agtcatcaat tcccagaaaa gagcgtggtt
    39121 caagtgtccg ccaccattgt tgataagtgc ttgacggata tcagctggga tagattctac
    39181 atcagcaagc aaggcttcaa ggtcttcacc gatttcaggg tgtttttcta aagctgcatt
    39241 ggcattgttg acataagttt gatggtgttt gtcatggtgc aaatgcattg tttccgcatc
    39301 gatgtatggt tccaaagcgt cgtatgcata tggaagttct ggtaagataa tagccatctg
    39361 taatacctct ttttctttct atatgaaaat gataacgcaa acattcactt ttttcaagtt
    39421 ttttgcttat agataaggaa atcactgaca tactttctaa taaaataagc aaatcagcaa
    39481 gaaacccacg acaagataat cctgatgcgg gttgtagttt caacaaatgt caattgacct
    39541 gactagcaat ctgtaagagt gccttttcaa aaaggaaacc tttttcataa agacctgtct
    39601 taatctgata gtctgtctca atcaaatagg aaatagcttg cttcagaaag ctcaaagaaa
    39661 gtcctctcga atctcttaat gcaaacttga tttgataagg atttgggtta cgtcccagat
    39721 aactacctaa actacttgca atctgcgatt ctgtttggcc agactccgcc aaaatcttca
    39781 cctgagtaaa agtccgaaat tgtcccagca tgactgcaat cagtttgatt tcatcttccc
    39841 cttgcaaggt caagtctctc accaaatcgc gcgcctgatc catcttttta gtcagaataa
    39901 actgagttaa atcaaaaata ttgtcctgca aggtcttggg aattgcgtta acaatatcct
    39961 cttcctcgat aacagaatcc gccttatagg actgtaaaaa gagaagattt ttctggattt
    40021 cgctaaattg aaaccccgac ttgatgagga gattttcaaa agaatgattg gtaaactgca
    40081 gaccttgttt ctgactccac ttttggaagt actggcgcaa ttcttgttct tttacttcta
    40141 ctgcatcgaa ggccttggca tcacgcttaa gtaatttgac taaccgtctt ttgctatcca
    40201 gctttccttc tgcaaagatt atcaacttgg ttgttggaga aggattgtca aggtattcct
    40261 caaatgactt aagctcatca tctgtcaaaa agcgtttctt agcagtcgtg atatccataa
    40321 aataatctaa tatcacgatt ttctcatccg caaagaaagg aaggctgacc aactccagtt
    40381 ccacatcctt gtaaactact tctttcatat caaagtaggc aaagttgagg tcagcagaat
    40441 catacccaat ctgtttcaac acttgactct tcatcacttc aaactgcccc tgatctgtcc
    40501 ctgtaaatag gctcaggctc ggtaaatttg ataaagtcaa cttctgactt tcttcaatgg
    40561 ctagcatcgt ctctcctttc ttcagatttt tcgatttaat ttagtcaata tagcgcaatt
    40621 tcccacggaa atcttctaag ctctcgtagc ctttttccac catgattgct ttcagttcat
    40681 tggtaatgcg gtcaaaagca ctgacgcctt ctttgtgaag ggtcgttccc acctgcacca
    40741 tacttgctcc acagaggatg tgttcaaagg catctcgacc agtcagaacg ccacctgttc
    40801 cgataatttg gatttgagga tttaaacgtt gataaaaggc gtgaacattg gctagagcag
    40861 tcggtttgat gtattctcca ccaattccac caaaaccatt cttaggccga ataacgacag
    40921 attcgtcttc tatatagagg ccgtttccga tagagttaac gcagttgaca aacttgagcg
    40981 gatatttgtt gaaaatagct gccgcttgat caaagtgaac aatatcaaaa taaggtggca
    41041 atttaattcc aagaggtttg gtgaagtaag caaacacttc tgccaaaatc cggtctgttg
    41101 tctcaaaatc ataggcaatc tgaggtttac ctggaacatt tggacaggaa agatttagct
    41161 cagtcagacc acgaaaatca ctctcttgga cttttttcaa aatagtatgg gtttcctctg
    41221 gagacatgcc gaccagagat aagaagaaag ttcggttcga ctctttttcc tgcaaatcta
    41281 aaagataatc caaataatag tctaagccat tatttggcaa gcccatagag ttgatggaac
    41341 caagtggaac atcttggtag cgtggctcag gattcccctg acggaagtcc aaggtcgctg
    41401 tcttagtaac aaaggttcct gccgctgagt ttttgacctc ttctaactcc tctatcgtca
    41461 tacaagccac acctgctgca ttcatcaagc aattgtcaaa ctcaaaacca gcaatttgtg
    41521 ttttcgttga taccatgatt ctaatcctcc agatttcttt tattgctaat attataccat
    41581 aattttaatt ctaggtttac tagattctgt ggttctatct atttattcgg aaaagaaagt
    41641 ctagtacaga agtcatgcta tggaaacagc tagtatattg gaagtttgaa caaggcttgg
    41701 gtaacagact tttgaatgaa gtccaagcaa caaggagaaa tctcaaccat gagtccattc
    41761 catgactctg ttgctctaga aaaccttgca atagtcaagt gataacgaat aaaactttgg
    41821 attgaaatat ctccatgatt atctattacg aggagaaatc tcaaccttta tcatttttaa
    41881 agaaatatag taaaatgaaa caagaacagg agaaatcgat caggacagtc aaatcgattt
    41941 ctaacaatgt tttagaagtt gaagtgtact attctagttt caatctacta tacatgtaaa
    42001 tctctacttt cgcaaaatgg attttcagaa cagtatccca atatagttaa aaactataaa
    42061 aaagagagga cgttcccctc ttaaaatctt attttactgc ttctttcaaa gcatctacct
    42121 tatccaaacg ttcccatgga agatcaatat ctgtacgtcc catgtgaccg taagccgatg
    42181 tttgacggta aattggacgc ttgaggtcca gcatttggat aatccctgca gggcgaaggt
    42241 caaagatttg acgagccgct ttttcaagtt gactttcagc tactgttcct gtaccgaaag
    42301 tatcgatacg aacagaaaca ggttgcgcaa caccgatagc ataggccaac tgcacttctg
    42361 ccttcttagc aaggcctgct gcaacgatat tcttggcaat atagcgagcc gcataagagg
    42421 ctgaacgatc caccttagtc gcatctttac cagagaaggc accaccacca tgacgagagt
    42481 agccaccata agtatctaca ataatcttac gaccagtcaa acctgagtcc ccttgaggac
    42541 caccgattac aaaacgacct gtcggattga taaagaattt tgtcttatca tcaagataag
    42601 aagatggaat aacttctttg atgaccttgt caatcacatc ttgatggatt tgttcattag
    42661 tggcctctgg atcatgctga gtagaaataa cgactgtatc tacacgtacc ggacgatcat
    42721 tttcatcgta ctcaactgta acttgtgatt ttgcatctgg acggagatag ctaatttctc
    42781 cagacttacg aagttctgcc agacgacgaa ccaatttatg actgagtgca attggcaatg
    42841 gcatgagctc ttctgtttca tctactgcaa atccaaacat gagcccttgg tcacctgctc
    42901 caatcaagtc cagtggatct tgatcagcat ttccacgaac ctccaaggct tcgttaacac
    42961 cttgagcgat gtcaggagat tgttccacca aagatgggtg tactcccacc gtctcagcag
    43021 aaaatccata ttctgtattg gtataaccaa tctctgcaat ggtatcacga accacacggt
    43081 taatatccac ataggcattt gtagaaattt caccaaaaac gtggacagaa ccagtatata
    43141 cagctgtttc agcagcaacg tgcgcctctg gatcctttgc taaaatagca tccaaaatcg
    43201 catctgaaat ttggtctgca atcttatccg gatgcccctc agatacagat tcagacgtga
    43261 ataatttacg ttctgacata aaaatgtccc cccttaaaaa atattgttat agagttacaa
    43321 agtactgata ggaaaactct ttgtaataaa tacctaccat cttatcggga ctatataact
    43381 ttatcattat accattttta atcgcaattt gcagtcttta atgtagtgtt tcggtttaga
    43441 tagttcgttc tcataaataa aaaagttgga gctcaatact ccaacaattt ctattaaaat
    43501 gtttggcgtt tagctttacg ctctgcacga ccgcgagcgc gattttcagc acgcttggtt
    43561 ttacggcgct tttcatcaac cgcccattga attttcttct tataacccgg tttgactttt
    43621 ttctttttct ttttaaccaa accaatcatt tcgatatcaa gtttatcttg ttttttctca
    43681 cggttagcac gacgatcacg gtcataggta tcttgaaatt ccccgtcttt gaccatctta
    43741 ggactaaact tgattcccaa tttctccaac tcacggatat ccgagtcatc acttggctga
    43801 taaagggtaa tagctgtacc tggtaggcca tttcgtccag tacggccaac acggtgaaca
    43861 aaaaaagata agtcttgcgg aatggcatca ttgatgacat ggctgacacc ttcaatgtca
    43921 atcccacgcg ctgccaaatc tgttgcgaca atatactcaa aatccagatt ttgcacctga
    43981 ttcatgattc gcttgcgttc acgaggggca atatcgccat ggatttttgc aaccttcaag
    44041 ccttgagcag tcagatatga atgcaattca tcagcacgcg ttttagtgtt aacaaaaatc
    44101 attgccaaat acggctgcat caactgagtc aactggtaaa tttgagcatt cttatcatgt
    44161 cccttggtcg aaatcaacca attatcaatg gtgtcagaaa taaccgtttt agtcttaatt
    44221 ttctccataa caggatttga taagtatttt ttcaagaatg gttgcagttt ttgtgggata
    44281 gtcgctgaga agaccatgaa ttgcaagtct tttggaagac tgccagcaat cttatcaaca
    44341 gtttccaaga atcccatatc caaggtcata tctgcttcat caacaacaaa tgtcttggct
    44401 ttatgaatag ctaaatcacc agatttaacc aagtcgtaga tacggcctgg tgttccaata
    44461 acaatatgag gctgattgct tgccaatttc tcaatctggc gagccttatc cgtaccaccc
    44521 acataattaa ccacacgaac ttcgacatct gagtgagctg aaatctgacg cgctacttgg
    44581 taaatttgag tagccaactc acgactcggt gcagtaatca ctgcttgtac actatcgcta
    44641 gcttcatcta attgctggaa aatcggtaac aagaaagtgt gagtcttacc tgaacctgtt
    44701 tttgattctc ctactaggtc acgacctgcc aaaacaatag gaatcaactt gtcttgcacc
    44761 tctgttggag ttgtaaattt taactccttc aaggcttctc taatatagtt tttaaattga
    44821 aatttcgtaa atgacataac atcctcgatt ctatctatct tatcaattat accatatttt
    44881 gaacattttc agtagtccga ctcatctgac ctatcacaag gctctcaatt tctctaaata
    44941 tagtaaaatg aaataagaat aggatgaatc gatcaggaca gtcaaatcga tttctaacaa
    45001 tgttttagaa gcagaggtgt actattctag tttcaatcta ctatacctct cttatactaa
    45061 aaatcataca tttgctttct ttccaaaatg caaaaagaga agaccaaatt ggtcttctct
    45121 cagccttaaa gcttgcgact cagatagatt tgtcaaacag tcaaacagtt gcttaagaat
    45181 cttgtaaaag tcgaaagctt ctagaaaaat tagtacttaa tcatctttcc gcttgcgacc
    45241 aagaagcaac actgctagac ctgcaagaag agagctagtc actagtccag tgagtgaaag
    45301 tggtgcagta ctacccgcat ttggcaatgt agcttgtttt tccttttctc ctgctggacc
    45361 ttgagctggt ggattctctt caggttttct tggttgttct gattgatgtc tatctgcctg
    45421 attattatca gttccctgct ctccccctgg attcactggt ggaactggat ttggttgagg
    45481 tgctggttgt ggcgttggtg ccggctgtgg ttgtggacta ggatcttgct tagcttcaaa
    45541 gacccactta ccgacgaagg ttagatttga cccctcttcc acttcttggt aacctaagaa
    45601 tgtccatgta ccatttgcaa cagcaacttc tacaggcatc ggtgcttctg gaacgaaagc
    45661 aatcgctaca gaagaacttg tagtatatgt tccactttgt gggagtaagc tcaatacttc
    45721 tgctggcaag ttgttgtctg cggttgcact ttcgaagcgg taagtcacct tataggtttg
    45781 agtttctggt gcaggcaaaa cattaactga tacagacacc tcagtagaag aaccatctgg
    45841 atagtcaact cgcaccttac ctgtgtaagt acctggtttt gttgtgtcaa tttgacctgc
    45901 aggtgtaata tcaactacct tagtgccagc tggaaggttt ggcaagttcg tcacattatc
    45961 ggtcaagtca ggtgtttgtc caaccttgat agtttcttcc gttacctgag gcgtataa
//
LOCUS       DAVLDI010000011        45525 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLDI010000011 DAVLDI010000000
VERSION     DAVLDI010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45525
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.011"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            511..963
                     /locus_tag="VXD01_000578"
     CDS             511..963
                     /locus_tag="VXD01_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0601013.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            982..2319
                     /locus_tag="VXD01_000579"
     CDS             982..2319
                     /locus_tag="VXD01_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV0601014.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIRGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2398..3282
                     /locus_tag="VXD01_000580"
     CDS             2398..3282
                     /locus_tag="VXD01_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0601015.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3282..4115
                     /locus_tag="VXD01_000581"
     CDS             3282..4115
                     /locus_tag="VXD01_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0601016.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4133..6226
                     /gene="nanB"
                     /locus_tag="VXD01_000582"
     CDS             4133..6226
                     /gene="nanB"
                     /locus_tag="VXD01_000582"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV0601017.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFENATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6239..7342
                     /locus_tag="VXD01_000583"
     CDS             6239..7342
                     /locus_tag="VXD01_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0601018.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7516..8214
                     /locus_tag="VXD01_000584"
     CDS             7516..8214
                     /locus_tag="VXD01_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0601019.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8233..9750
                     /locus_tag="VXD01_000585"
     CDS             8233..9750
                     /locus_tag="VXD01_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0601020.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9875..11203
                     /locus_tag="VXD01_000586"
     CDS             9875..11203
                     /locus_tag="VXD01_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0601021.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11455..12321
                     /locus_tag="VXD01_000587"
     CDS             11455..12321
                     /locus_tag="VXD01_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0601022.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12337..13176
                     /locus_tag="VXD01_000588"
     CDS             12337..13176
                     /locus_tag="VXD01_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0601023.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13448..13900
                     /locus_tag="VXD01_000589"
     CDS             13448..13900
                     /locus_tag="VXD01_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0601024.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14033..14341
                     /locus_tag="VXD01_000590"
     CDS             14033..14341
                     /locus_tag="VXD01_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601025.1"
                     /translation="MDGQGITVDEMAWIIRGIVNGLIGRYIKLGTYAAKYGISMARSI
                     LSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFANNIAAAWDAHDKIPNNGRINF
                     "
     gene            14351..14650
                     /locus_tag="VXD01_000591"
     CDS             14351..14650
                     /locus_tag="VXD01_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601026.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFDEHTWSTILIASLFGV
                     YDYKPIDKNRKKSKRKKKKEKIDLFMVGTYESFTDKKENSLQRKMMEEQTWHKKE"
     gene            14632..15276
                     /locus_tag="VXD01_000592"
     CDS             14632..15276
                     /locus_tag="VXD01_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV0601027.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15445..16362
                     /locus_tag="VXD01_000593"
     CDS             15445..16362
                     /locus_tag="VXD01_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV0601028.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16380..17264
                     /locus_tag="VXD01_000594"
     CDS             16380..17264
                     /locus_tag="VXD01_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0601029.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17280..18131)
                     /locus_tag="VXD01_000595"
     CDS             complement(17280..18131)
                     /locus_tag="VXD01_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV0601030.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18331..20388
                     /gene="pbp2b"
                     /locus_tag="VXD01_000596"
     CDS             18331..20388
                     /gene="pbp2b"
                     /locus_tag="VXD01_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV0601031.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMAIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQPIVFQGSAPINSWYTQAYGSFPITAVEALEYSSN
                     AYMVQTALGIMGQTYQPNMFVLTNNLESAMGKLRSTFAEYGLGASTGIDLPDESTGFI
                     PKEYNFANYITNAFGQFDNYTPMQLAQYVGTIANNGVRIAPHIVEGIYGNNEQGGLGN
                     LIQSVESKEMNKINISESDVSILQQGFYQVSHGGSALTTGRAFSNGASVSISGKTGTA
                     ESYVEGGQEANNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYNQHH
                     PMN"
     gene            20399..20995
                     /gene="recR"
                     /locus_tag="VXD01_000597"
     CDS             20399..20995
                     /gene="recR"
                     /locus_tag="VXD01_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV0601032.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSDDDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21171..22214
                     /locus_tag="VXD01_000598"
     CDS             21171..22214
                     /locus_tag="VXD01_000598"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV0601033.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHDPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALELAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22298..23671
                     /locus_tag="VXD01_000599"
     CDS             22298..23671
                     /locus_tag="VXD01_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV0601034.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGENIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGVHDQILLKGSNSMNLAKLVE
                     SLENETK"
     gene            23658..24269
                     /locus_tag="VXD01_000600"
     CDS             23658..24269
                     /locus_tag="VXD01_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0601035.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIAALQFFAIDQLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            24360..25064
                     /locus_tag="VXD01_000601"
     CDS             24360..25064
                     /locus_tag="VXD01_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV0601036.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25283..26656
                     /gene="ftsA"
                     /locus_tag="VXD01_000602"
     CDS             25283..26656
                     /gene="ftsA"
                     /locus_tag="VXD01_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV0601037.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26673..27932
                     /gene="ftsZ"
                     /locus_tag="VXD01_000603"
     CDS             26673..27932
                     /gene="ftsZ"
                     /locus_tag="VXD01_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV0601038.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVSPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27937..28608
                     /locus_tag="VXD01_000604"
     CDS             27937..28608
                     /locus_tag="VXD01_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV0601039.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28618..29157
                     /locus_tag="VXD01_000605"
     CDS             28618..29157
                     /locus_tag="VXD01_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV0601040.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29157..29420
                     /locus_tag="VXD01_000606"
     CDS             29157..29420
                     /locus_tag="VXD01_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV0601041.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29417..30202
                     /locus_tag="VXD01_000607"
     CDS             29417..30202
                     /locus_tag="VXD01_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV0601042.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEYL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30211..30999
                     /gene="divIVA"
                     /locus_tag="VXD01_000608"
     CDS             30211..30999
                     /gene="divIVA"
                     /locus_tag="VXD01_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV0601043.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPVPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31347..34139
                     /locus_tag="VXD01_000609"
     CDS             31347..34139
                     /locus_tag="VXD01_000609"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV0601044.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            34548..34928
                     /locus_tag="VXD01_000610"
     CDS             34548..34928
                     /locus_tag="VXD01_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601045.1"
                     /translation="MKSKRLALISGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGW
                     VGGILAIIGGSLFLATLKKFKSEE"
     gene            35224..35412
                     /locus_tag="VXD01_000611"
     CDS             35224..35412
                     /locus_tag="VXD01_000611"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601046.1"
                     /translation="MENNDSFTKLKESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQ
                     TVLSFLVLTSFFVKNCVK"
     gene            35463..36155
                     /locus_tag="VXD01_000612"
     CDS             35463..36155
                     /locus_tag="VXD01_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV0601047.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            36208..38619
                     /locus_tag="VXD01_000613"
     CDS             36208..38619
                     /locus_tag="VXD01_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV0601048.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYETYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TDVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGNGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            38830..39531
                     /locus_tag="VXD01_000614"
     CDS             38830..39531
                     /locus_tag="VXD01_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601049.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            39533..42241
                     /locus_tag="VXD01_000615"
     CDS             39533..42241
                     /locus_tag="VXD01_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0601050.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEDHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAS
                     IVTFTTMTRFVDEERTHAGIFKALGYRSKDIITKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATDQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNVSAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPSTI
                     LFYPQVGWEVYVIPVVAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(42337..42828)
                     /gene="tpx"
                     /locus_tag="VXD01_000616"
     CDS             complement(42337..42828)
                     /gene="tpx"
                     /locus_tag="VXD01_000616"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV0601051.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(42951..43880)
                     /gene="psaA"
                     /locus_tag="VXD01_000617"
     CDS             complement(42951..43880)
                     /gene="psaA"
                     /locus_tag="VXD01_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV0601052.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(43912..44760)
                     /locus_tag="VXD01_000618"
     CDS             complement(43912..44760)
                     /locus_tag="VXD01_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV0601053.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(44757..45479)
                     /locus_tag="VXD01_000619"
     CDS             complement(44757..45479)
                     /locus_tag="VXD01_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV0601054.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT        13854 a         8147 c         9994 g        13530 t
ORIGIN      
        1 tttttggtga aacgagatgt agaaaggaga tttagccaaa gagtctatta gtgctagaat
       61 aatagattag aattatttta gaaaaacgaa gtgagcagct tataaattca agtccccaaa
      121 tagattcata ctagtatctt ttgcaaaaaa taaagggcga cttccttcat gaatatcaat
      181 ttcatctata aggaaggtag ctaattgaac taacttattt attctgtttg tcgctagaaa
      241 aatcagacct ccttgtgaag attgaggaga tactgaatga aaatcaaaga agaaactagc
      301 aagctagtag cagattgccc aaaacaccgc tttgaggttg tagataagac tgacgtatat
      361 aatccaaggt gaagcgactg tggtttgaag agattttcaa agagtatagg ctagagagta
      421 gtgtttttat gtccttctag tagaaaatgc tagacagaag aatggggaac ttggatagga
      481 gaaatagatt gagaaaggag gttagaagag atgattatta caaaaattag ccgtttagga
      541 acttatgtgg gagtaaatcc acattttgca acattaatag attttctaga aaaaacagga
      601 ctagaaaatt taacagaagg ttcgattgct atcgatggta atcgattgtt tgggaattgc
      661 tttacttatc tagcagatgg tcaagcaggg gctttctttg aaacacacca aaaatatttg
      721 gatattcatt tagttttgga aaacgaagaa gccatggctg ttacatcgcc ggaaaatgta
      781 agcgttaccc aagaatatga tgaagagaaa gatattgaat tatacacagg gaaagtggaa
      841 cagttggttc atttgagagc tggtgaatgc ctcatcactt ttccagaaga tttacatcaa
      901 cccaaggttc gtataaatga tgaacctgtg aaaaaagttg tctttaaagt tgcgatttct
      961 taatgtagaa agagaagaac gatgaaaaaa atgagaaagt ttttatgtct agctggaatt
     1021 gcgctagcgg ctgttgcctt ggtagcttgt tcaggaaaaa aagaagctac aactagtact
     1081 gaaccaccaa cagaattatc tggtgagatt acaatgtggc actcctttac tcaaggaccc
     1141 cgtttagaaa gtattcaaaa atcagcagat gctttcatgc aaaagcatcc aaaaacgaaa
     1201 atcaagattg aaacattttc ttggaatgac ttctatacta aatggactac aggtttagca
     1261 aatggaaatg tgccagatat cagtacagct cttcctaacc aagtaatgga aatggtcaac
     1321 tcagatgctt tggttccgct aaatgattct atcaagcgta ttggacaaga taaatttaac
     1381 gaaactgcct taaatgaagc aaaaatcgga gatgattact actctgttcc tctttattca
     1441 catgcacaag tcatgtgggt tagaacagat ttgttaaaag aacataatat tgaggttcct
     1501 aaaacttggg atcaactcta tgaagcttct aaaaaattga aagaagctgg agtttatggc
     1561 ttgtctgttc cgtttggaac aaatgactta atggcaacac gtttcttgaa cttctacgta
     1621 cgtagtggtg gaggaagcct cttaacaaaa gatcttaaag cagacttgac aagccaactt
     1681 gctcaagatg gtattaaata ctgggttaaa ttgtataaag aaatctcacc tcaagattct
     1741 ttgaacttta atgtccttca acaagctacc ttgttctatc aaggaaaaac agcatttgac
     1801 tttaactctg gcttccatat cggaggaatt aatgccaaca gtcctcaatt gattgattcg
     1861 attgatgctt atcctattcc aaaaatcaaa gagtctgata aagaccaagg aattgaaacc
     1921 tcaaacattc caatggttgt ttggaaaaat tcaaaacatc cagaagttgc taaagcattc
     1981 ttagaagcac tttataatga agaagactac gttaaattcc ttgattcaac tccagtaggt
     2041 atgttgccaa ctattagggg gattagcgat tctgcagcct ataaagaaaa tgaaactcgt
     2101 aagaaattta aacatgctga agaagtaatt actgaagctg ttaaaaaagg tactgctatt
     2161 ggttatgaaa atggaccaag tgtacaagct ggtatgttga ctaaccaaca cattattgaa
     2221 caaatgttcc aagatatcat tacaaatgga acagatccta tgaaagcagc aaaagaagca
     2281 gaaaaacaat taaatgattt atttgaggct gttcagtaga tgtaaaagac tagaaaatag
     2341 gtgggctagt gagctgaaaa gttctagccc aatcttgtaa aagaagggag aaggagaatg
     2401 gttaaagaac gtaatttaac tcgctggata tttgttttgc cagctatgat tatcgtagga
     2461 ttactctttg tttatccgtt tttctcgagt attttttata gctttaccaa taagcatttg
     2521 attatgccta attataaatt tgttggtttg gctaactata aagctgtgct atcagatccc
     2581 aacttcttta atgcgttctt taattcaatt aagtggaccg ttttctcatt agttggtcaa
     2641 gttttagtag ggtttgtatt ggctttagct cttcacagag tacgccactt caagaaatta
     2701 tataggacct tattgattgt tccttgggca tttcctacca tcgttattgc cttctcttgg
     2761 cagtggattc taaacggggt ttatggctac ttacctaatc taatcgtaaa attaggttta
     2821 atggaacata cacctgcatt tttgacagat agtacatggg cattcctatg tttggtgttt
     2881 atcaacattt ggtttggagc accaatgatt atggttaatg tgctttcagc tttgcaaaca
     2941 gtaccagaag aacaatttga ggctgctaag atagatggtg cttcaagttg gcaggtgttc
     3001 aagtttatcg tctttccaca tattaaagtg gttgtaggac ttctagttgt tttgagaact
     3061 gtatggatct ttaataactt tgacattatc tacctcatta ctggtggtgg accagccaat
     3121 gctacaacga cgcttccaat ttttgcttac aacctgggtt ggggaactaa attgttgggt
     3181 cgtgcttcag cagttacagt attgctcttt atcttcttgg tggcgatttg ctttatctac
     3241 tttgctatca tcagtaagtg ggaaaaggag ggtagaaaat aatgaagaag aaatccagta
     3301 tttatttaga tattctctca catgtacttt tagttggtgc gaccatcgtt gcaattttcc
     3361 cattggtatg gattatcata tcttctgtca aagggaaagg ggaattaact cagtatccaa
     3421 cacgattttg gcctgaacag tttacattag attatttcac tcatgttatc aacgatttgc
     3481 acttcattga taacattcga aacagtttaa tcattgcctt ggctacaacc ctcattgcga
     3541 ttattatttc tgctatggca gcctatggta ttgttcgatt ctttcctaaa ttgggagcaa
     3601 tcatgtcgag actactcgtc attacctaca ttttcccacc aattttgtta gcaattccct
     3661 attcaattgc cattgctaaa gttgggttaa caaatagttt atttggcttg atgatggttt
     3721 atctatcttt tagtgttcca tatgcagttt ggctcttagt tggatttttc caaacagttc
     3781 caattggaat tgaagaagcg gctagaattg atggtgcaaa taaatttgtt acgttttata
     3841 aggttgtgct accgattgta gcaccaggta ttgtagcaac agctatttat acatttatca
     3901 atgcttggaa tgaattcctg tatgccttga ttttaattaa caatacagga aagatgacag
     3961 tagcagtagc ccttcgttca cttaatggtt cagaaatact agactgggga gatatgatgg
     4021 cagcgtctgt tattgtagtt cttccatcaa ttattttctt ctctatcatc caaaataaga
     4081 ttgcaagtgg attatcagaa ggatctgtga agtagacgaa agaaggaaaa aaatgaataa
     4141 aagaggtctt tattcaaaac taggaatttc tgttgtaggc attagtcttt taatgggagt
     4201 ccccactttg attcatgcga atgaattaaa ctatggtcaa ctgtccatat ctcctatttt
     4261 tcaaggaggt tcatatcaac tgaacaataa gagtatagat atcagctctt tgttattaga
     4321 taaattgtct ggagagagtc agacagtagt aatgaaattt aaagcagata aaccaaactc
     4381 tcttcaagct ttgtttggcc tatctaatag taaagcaggc tttaaaaata attacttttc
     4441 aattttcatg agagattctg gtgagatagg tgtagaaata agagacgccc aaaagggaat
     4501 aaattattta ttttctagac cagcttcatt atggggaaag cataaaggac aggcagttga
     4561 aaatacacta gtatttgtat ctgattctaa agataaaaca tacacaatgt atgttaatgg
     4621 aatagaagtg ttctctgaaa cagttgatac atttttgcca atttcaaata taaatggtat
     4681 agataaggca acactaggag ctgttaatcg tgaaggtaag gaacattacc tcgcaaaagg
     4741 aagtattgat gaaatcagtc tatttaacaa agcaattagt gatcaggaag tttcaaatat
     4801 tcccttgtca aatccatttc agttaatttt ccaatcagga gattctactc aagctaacta
     4861 ttttagaata ccgacactat atacattaag tagtggaaga gttctatcaa gtattgatgc
     4921 acgttatggt gggactcatg attctaaaag taagattaat attgccactt cttatagtga
     4981 tgataatggg aaaacgtgga gtgagccaat ttttgctatg aagtttaatg actatgagga
     5041 gcagttagtt tactggccac gagataataa attaaagaat agtcaaatta gtggaagtgc
     5101 ttcattcata gattcatcca ttgttgaaga taaaaaatct gggaaaacga tattactagc
     5161 tgatgttatg cctgcgggta ttggaaataa taatgcaaat aaagccgact caggttttaa
     5221 agaaataaat ggtcattatt atttaaaact aaagaagaat ggagataacg atttccgtta
     5281 tacagttaga gaaaatggtg tcgtttatga tgaaacaact aataaaccta caaattatac
     5341 tataaatgat aagtatgaag ttttggaggg aggaaagtct ttaacagtcg aacaatattc
     5401 ggttgatttt gatagtggct ctttaagaga aaaacataat ggaaaacagg tccctatgaa
     5461 tgttttctac aaagattcgt tatttaaagt gactcctact aattatatag caatgacaac
     5521 tagtcagaat agaggagaga gttgggaaca atttaagttg ttgcctccgt tcttaggaga
     5581 aaaacataat ggaacttact tatgtcccgg acaaggttta gcattaaaat caagtaacag
     5641 attgattttt gcaacatata ctagtggaga actaacctat ctcatttctg atgatagtgg
     5701 tcaaacatgg aagaaatcct cagcttcaat tccgtttgaa aatgcaacag cagaagcaca
     5761 aatggttgaa ctgagagatg gtgtgattag aacattcttt agaaccacta caggtaagat
     5821 agcttatatg actagtagag attctggaga aacatggtcg gaagtttcgt atattgatgg
     5881 aatccaacaa acttcatatg gcacacaagt atctgcaatt aaatactctc aattaattga
     5941 tggaaaagaa gcagtcattt tgagtacacc aaattctaga agtggccgta agggaggtca
     6001 attagttgtc ggtttagtca ataaagaaga tgatagtatt gattggaaat accactatga
     6061 tattgatttg ccttcgtatg gttatgccta ttctgcgatt acagaattgc caaatcatca
     6121 cataggtgta ctgtttgaaa aatatgattc gtggtcgaga aatgaattgc atttaagcaa
     6181 tgtagttcag tatatagatt tggaaattaa tgatttaaca aaataaagga gaaaaaacat
     6241 ggttaaatac ggtgttgttg gagcagggta ttttggagct gaattggctc gctacatgca
     6301 aaagaatgat ggagcagaga ttactcttct ctatgatcca gataatgcag aggcgattgc
     6361 agaagaattg ggagcaaaag tagcaagttc cttagatgag ttggtttcta gcgatgaagt
     6421 agattgtgtt atcgtcgcaa ctccaaataa tcttcataag gaaccggtta ttaaggctgc
     6481 acagcatggt aaaaatgttt tctgtgaaaa accaattgcg ctttcttatc aagattgtcg
     6541 cgagatggta gatgcgtgta aagaaaacaa tgtaaccttt atggcaggac atattatgaa
     6601 tttctttaat ggtgttcatc atgcaaaaga actcattaat caaggagtta tcggagacgt
     6661 tctatattgt catacagctc gtaatggttg ggaagaacaa caaccgtcag tatcatggaa
     6721 aaaaattcgt gaaaaatcag gtggtcactt gtatcaccac atccatgaat tggattgcgt
     6781 tcaattcctt atggggggca tgcctgaaac tgtaaccatg acaggtggaa atgtggccca
     6841 tgaaggtgaa catttcggtg atgaagatga tatgattttt gtcaatatgg aattttctaa
     6901 taagcgtttt gctttgttag aatggggttc agcttatcgt tggggtgaac attatgtctt
     6961 aatccaagga agcaaaggtg ccatccgctt agacttattc aactgtaaag gaactcttaa
     7021 gctagatggg caagaaagct atttcttgat tcacgaatcg caagaagaag atgatgatcg
     7081 gactcgtatc tatcatagta cagagatgga tggagcaatt gcttatggta aaccaggtaa
     7141 acgtactcca ttatggctat catctgtcat tgataaagaa atgcgctatc tgcatgagat
     7201 tatggaagga gctccagtat cagaagaatt tgcaaaactt ttgacaggtg aagctgccct
     7261 agaagcaatt gctactgcag atgcttgtac ccagtctatg tttgaagatc gcaaagtaaa
     7321 attgtcagaa attgtaaaat aaattttggt attctcctat ttataggtcg acttgctcct
     7381 ctgaaagtac ttttagagga gctgtttgac tttgctagtt tttgaaactg aaatctatta
     7441 tactacaaac tattgaaagc gttttaattt taaggtataa taatctcata gaaataaaga
     7501 aaaggaggaa agaggatgcc acagattagc aaagaagcct tgattgagca aatcaaagat
     7561 ggaatcatcg tttcttgtca ggctcttcct catgaaccgc tttatacaga agcgggaggg
     7621 gtgattccct tgctggtcaa agcggctgag caaggtggag cagtcggtat ccgagcaaac
     7681 agtgttcgcg atatcaagga aattaaggaa gtcactaaac ttccaatcat tgggattatc
     7741 aaacgtgatt atccacctca ggaacccttc atcacggcta ctatgaaaga agttgatgaa
     7801 ttggcagaac tggacatcga ggtgattgct ctggattgta ccaagcgtga acgctacgat
     7861 ggtttggaaa ttcaagagtt cattcgtcag gttaaggaga aatatcctaa tcagcttttg
     7921 atggctgata ctagtatctt cgaagaaggg ctagcagctg tagaagcagg aattgacttt
     7981 gtcggaacaa ccttatcagg ctacacatcc tacagtccaa aagtagacgg tccagatttt
     8041 gaattgatta agaaactctg tgatgccggt gtagatgtca ttgcagaagg aaaaattcat
     8101 acaccagaac aagccaaaca aatccttgaa tatggagtgc gaggcatcgt tgttggtggc
     8161 gccattacta gaccaaaaga gattacagaa cgcttcgttg ctagtcttaa ataagatgtg
     8221 agggggagtt ttatgtttaa agttttacaa aaagttggaa aagcttttat gttacctata
     8281 gctatacttc ctgcagcagg tctacttttg gggattggtg gtgcactttc aaacccaacc
     8341 acgatagcaa cttatccaat actagacaat agtatttttc aatcaatatt ccaagtaatg
     8401 agctctgcag gagaggttgt attcagtaat ttgtcactac ttctctgtgt gggattatgt
     8461 attggcttag cgaaacgaga taaaggaacc gctgcgttag caggagtaac tggttactta
     8521 gttatgactg caacgatcaa agctttggta aaacttttta tggcagaagg atctgcaatt
     8581 gatactggag ttattggagc attagttgtc ggaatagttg ccgtatattt gcacaaccga
     8641 tataacaata ttcaattacc ttccgcttta ggattctttg gaggttcacg cttcgttcct
     8701 attgttacat cgttctcttc tatcttgatt ggctttgtct tctttgttat ttggccacct
     8761 ttccaacaac ttcttgtttc tacaggtgga tatatttctc aggcgggtcc aattggaact
     8821 tttctatatg gatttttaat gagactttct ggagcagtag gcttacatca tataatttac
     8881 cctatgtttt ggtatactga acttggtggt gttgaaactg ttgcaggaca aacagtggtt
     8941 ggagctcaaa aaatattttt tgctcaatta gccgatccgg cccattctgg attatttaca
     9001 gaaggaacaa ggttttttgc aggtcgtttc tcaacaatga tgttcggttt accggctgcc
     9061 tgtttagcga tgtaccatag tgttcctaaa aatcgtcgta aaaaatacgc gggtttgttt
     9121 tttggagttg ctttaacatc ttttattacc ggtattacag aaccaattga atttatgttt
     9181 ctattcgtca gtccggttct atatgttgtt cacgcattcc ttgatggtgt tagcttcttt
     9241 attgcagacg tcttaaatat ttcaatagga aacacatttt caggaggtgt aatcgatttc
     9301 actttatttg gaattttgca ggggaacgct aagacgaatt gggttcttca gattccaatt
     9361 ggacttattt ggagtgtttt gtattatatt atttttagat ggttcattac tcaattcaac
     9421 gttctaacgc caggacgagg agaagaagta gattctaaag aaatttctga atccgcagat
     9481 tcaacttcaa atactgcaga ttatttaaaa caggatagcc tacaaattat cagagccttg
     9541 ggtggatcaa ataatataga agatgtagat gcttgtgtga cacgtttacg tgtagctgta
     9601 aaagaagtta atcaagttga taaagcactt ttaaaacaaa ttggtgcagt tgatgtctta
     9661 gaagtgaagg gtggcattca agcaatctat ggagcaaaag caatcttata taaaaatagt
     9721 attaatgaaa ttttaggtgt agatgattaa gtacttactg acttaataaa aaacagagga
     9781 gagtgatgga tgagtaggat gaaatgaaat cgcatacaag aaataaagaa ctcattatcc
     9841 aagttggata cgcttattac ataggagaat acaaatgaaa tttagaaaat tagcttgtac
     9901 agtacttgcg ggtgctgcgg ttcttggtct tgctgcttgt ggcaattctg gcggaagtaa
     9961 agatgctgcc aaatcaggtg gtgacggtgc caaaacagaa atcacttggt gggcattccc
    10021 agtatttacc caagaaaaaa ctggtgacgg tgttggaact tatgaaaaat caatcatcga
    10081 agcgtttgaa aaagcaaacc cagatataaa agtgaaattg gaaaccatcg acttcaagtc
    10141 aggtcctgaa aaaatcacaa cagccatcga agcaggaaca gctccagacg tactctttga
    10201 tgcaccagga cgtatcatcc aatacggtaa aaacggtaaa ttggctgagt tgaatgacct
    10261 cttcacagat gaatttgtta aagatgtcaa caatgaaaac atcgtacaag caagtaaagc
    10321 tggagacaag gcttatatgt atccgattag ttctgcccca ttctacatgg caatgaacaa
    10381 gaaaatgtta gaagatgctg gagtagcaaa ccttgtaaaa gaaggttgga caactgatga
    10441 ttttgaaaaa gtattgaaag cacttaaaga caagggttac acaccaggtt cattgttcag
    10501 ttctggtcaa gggggagacc aaggaacacg tgcctttatc tctaaccttt atagcggttc
    10561 tgtaacagat gaaaaagtta gcaaatatac aactgatgat cctaaattcg tcaaaggtct
    10621 tgaaaaagca actagctgga ttaaagacaa tttgatcaat aatggttcac aatttgacgg
    10681 tggggcagat atccaaaact ttgccaatgg tcaaacatct tacacaatcc tttgggcacc
    10741 agctcaaaat ggtatccaag ctaaactttt agaagcaagt aaggtagaag tggtagaagt
    10801 accattccca tcagacgaag gtaagccagc tcttgaatac cttgtaaacg ggtttgcagt
    10861 attcaacaat aaagacgaca agaaagtcgc tgcatctaag aaattcatcc agtttatcgc
    10921 agatgacaag gagtggggac ctaaagacgt agttcgtaca ggtgctttcc cagtccgtac
    10981 ttcatttgga aaactttatg aagacaaacg catggaaaca ataagcggct ggactcaata
    11041 ctactcacca tactacaaca ctattgatgg atttgctgaa atgagaacac tttggttccc
    11101 aatgttgcaa tctgtatcaa atggtgacga aaaaccagca gatgctttga aagccttcac
    11161 tgaaaaagcg aacgaaacaa tcaaaaaagc tatgaaacaa tagtccttag ttattctata
    11221 aaaagtagtt ttttaaagaa cctaagagtg tataccccct tttccctcta cacagatagt
    11281 gtaagaaaag ggggcttttg tttaaaatgt aagaaactgt cacgaaatta aaatgaagtt
    11341 cttacataag cgaatcataa aaaatttcat tttgatttta aaacagttca agaaagtcaa
    11401 aaaattattc tatttgaaag agaggtgccg actgtgaaag tcaataaaat ccgtatgcgg
    11461 gaaacagtga tttcctacgc tttcctagca ccagtattat tcttctttgt catctttgtg
    11521 ttggctccga tggtgatggg cttcattaca agtttcttta actactcaat gactaaattt
    11581 gagtttgtag gcttggataa ctatatccgt atgtttaaag atcctgtctt tacaaaatct
    11641 ctgattaaca cagttatttt ggttattgga tctgtaccag ttgttgttct attctcactc
    11701 tttgtagcat ctcagaccta tcatcaaaat gtcattgcca gatccttcta ccgtttcgtc
    11761 ttcttccttc ctgttgtaac gggtagtgtt gccgtgacag ttgtttggaa atggatttat
    11821 gacccactat cagggattct aaactttgtc cttaagtcca gccacatcat cagccaaaac
    11881 atttcttggt tgggagataa aaactgggca ttgatggcga ttatgattat tctcttgacc
    11941 acttcagttg gtcagcccat catcctttat atcgctgcca tggggaatat tgacaattca
    12001 ctggttgaag cggcgcgtgt tgatggtgca actgagtttc aagttttttg gaagattaaa
    12061 tggccaagcc ttcttccaac aactctttat attgcaatca tcacaacaat taactcattc
    12121 cagtgttttg ccttgattca gcttttgaca tctggtggtc caaactactc aacaagtacc
    12181 ttgatgtact acctttacga aaaagccttc caattgacag aatacggcta tgccaacaca
    12241 attggtgtct tcttggcagt catgattgct atcgtaagct ttgttcaatt taaagtactt
    12301 ggaaacgacg tagaatacta aagaaaggag acagctatgc aatctacaga aaaaaaacca
    12361 ttaacagcct ttactgttat ttcaacaatc attttgctct tgttgactgt gctgttcatc
    12421 tttccattct actggatttt gacaggggca ttcaaatcac aacctgatac aattgttatt
    12481 cctcctcagt ggttccctaa aatgccaacc atggaaaact tccaacaact catggtgcag
    12541 aaccctgcct tgcaatggat gtggaactca gtatttatct cattggtaac catgttctta
    12601 gtttgtgcaa cctcatctct agcaggttat gtattggcta aaaaacgttt ctatggtcaa
    12661 cgcattctat ttgctatctt tatcgctgct atggcgcttc caaaacaagt tgtccttgta
    12721 ccattggtac gtatcgtcaa cttcatggga atccacgata ctctctgggc agttatcttg
    12781 cctttgattg gatggccatt cggtgtcttc ctcatgaaac aatttagtga aaatattcct
    12841 acagagttgc ttgaatcagc taaaatcgac ggttgtggtg agattcgtac cttctggagt
    12901 gtagccttcc cgattgtgaa accagggttt gcagcccttg caatctttac cttcatcaat
    12961 acttggaatg actacttcat gcaattggta atgttgactt cacgtaacaa tttgaccatc
    13021 tcacttgggg ttgcgaccat gcaggctgaa atggcaacca actatggttt gattatggca
    13081 ggagctgccc ttgctgctgt tccaatcgtc acagtcttcc tagtcttcca aaaatccttc
    13141 acacagggta ttactatggg agcggtcaaa ggataatact ctgagaaaat ctcttcaaac
    13201 tacgtcagcg tcaccttgcc atacttaagt attgcctgcg gttagcttcc tagtttgttc
    13261 ttcaattttc attgagtata ggaaaatcaa tctatcaaga tacagaagta tattttatag
    13321 atttagagaa tatagaggtt ataagtgtct acaaaatgga gggtatgcag ttactttatg
    13381 aagttttgtc agacacttat aaacttaaga atggttttag ttaactatca gaaacgaagg
    13441 aaagagtatg atttttgacg atttgaaaaa catcaccttt tacaaaggga ttcatcctaa
    13501 tttagacaag gctatcgact atctctacca acatcgtaag gattctttcg aattaggaaa
    13561 gtatgatatt gatggagata aagtctttct agttgttcag gaaaatgtcc tcaatcaagc
    13621 tgaaaatgat caatttgagt atcataagaa ctatgcagat ttgcatttgc tggtagaagg
    13681 acatgaatat tcgagctacg gttcacgtat caaagacgag gcagtagcat tcgacgaagc
    13741 gagtgacatt ggctttgttc attgtcatga acactaccca ctcttgttgg gttatcacaa
    13801 ttttgcgatt ttcttcccag gtgagccaca tcagccaaat ggttatgcag gcatggaaga
    13861 aaaggttcgg aaatatctct ttaaaatttt gattgattaa aaataggatg aattgttttt
    13921 ttgtaaagct ttgacaatac tctaccatga aattgatctt tgtgaggtag ggaaatgaga
    13981 ataaaatatt taaaaattgg tatcttctaa gtatgctgca agagctagtt tcttggatgg
    14041 acagggaatt acagttgatg agatggcttg gataattagg ggcattgtga atggattgat
    14101 tggtagatac ataaaattag gtacttatgc agccaagtat ggtattagta tggcgcgttc
    14161 gatcttaagt agggcagctg caactgcagc agcaagagta ggattatcga ccaagatttc
    14221 tggatggatt ttacgagtag ctgtgaatgt agctgatgta tatggtaatt ttgccaacaa
    14281 tattgctgca gcttgggatg cacatgataa aattcctaac aatggtcgta taaactttta
    14341 aaatgcgaga atgaaagcac tttgtatttt tttattgaat atgttagctt ggacagtgct
    14401 tgcaatgata attcgtggag ggctagatgg atttgatgag catacttgga gtactatttt
    14461 aattgcttcg ctgttcgggg tatatgatta taagcccata gataaaaata gaaaaaagtc
    14521 caaaagaaaa aagaaaaaag aaaaaataga tttgttcatg gtagggactt atgaaagctt
    14581 tactgacaaa aaagaaaaca gtttacaaag aaaaatgatg gaggagcaaa catggcacaa
    14641 aaaggagtaa gccttatcaa ggcagcattt gatacagaca actttctcat gcgttttagt
    14701 gagaaagtct tggacatcgt gacagccaat cttctttttg tcgtctcttg tttgcccatc
    14761 gtgacgattg gagtggctaa aatcagcctc tacgagacca tgttcgaagt taagaagagc
    14821 agacgggtgc ctgtttttaa aatctatcta agatctttca agcaaaatct gaaactaggt
    14881 cttcagctgg gtttaatgga gttaggaatt gtgtttctta ccctttcaga tctctatctt
    14941 ttctggggtc aaacagctct gcccttccaa ttgctgaaag ccatttgttt aggtattctg
    15001 atttttctta ctatcgtgat gctggctagt taccctatcg cggcacgtta tgacctatct
    15061 tggaaagaaa ttcttcaaaa aggattgatg ttggctagtt ttaactttcc ttggttcttc
    15121 ctcatgttag ccattcttgt cctcattgtg atggttcttt atctgtccgc cttcagtcta
    15181 ctcttaggtg gctcagtctt cttacttttt gggtttggac tattggtctt tatccagact
    15241 ggattgatgg agaaaatttt cgcaaaatac caataggagc cttatttctg aaactacttt
    15301 caaacgctcc aaacgctatt ctataagcga gaaactaaaa tctaagtgtc tataagatat
    15361 tgaaagcctt ttcggtaaag tgtatactaa agaagtaaag aaaaatctgc tttagcagaa
    15421 aataaaaata ataggagaaa atctatgtca gatttgaaaa aatacgaagg tgtcattcca
    15481 gccttctacg catgttatga tgatcaagga gaagtaagcc cagaacgtac gcgtgccttg
    15541 gttcaatact tcattgataa aggtgttcaa ggtctttatg tcaatggttc ttctggtgaa
    15601 tgtatctacc aaagtgttga agaccgcaag ttaatcttgg aagaagtcat ggcggtagcc
    15661 aaaggtaaat tgaccatcat tgctcatgtt gcctgcaaca atactaaaga tagtatggaa
    15721 cttgctcgcc atgctgaaag cttgggagta gatgctattg caacgattcc accaatttat
    15781 ttccgcttgc cagaatactc agttgccaaa tactggaacg atatcagttc tgcagctcca
    15841 aacacagact acgtgattta caacattcct caattggcag gggttgcttt gactccaagc
    15901 ctttacacag aaatgttgaa aaatcctcgt gttatcggtg ttaagaactc ttctatgcca
    15961 gttcaagata tccaaacctt tgtcagcctt ggtggggaag accatatcgt ctttaatggt
    16021 cctgatgagc agttcctagg aggacgcctc atgggtgcta gggctggtat cggtggtact
    16081 tatggtgcta tgccagaact cttcttgaaa ctcaatcagt tgattgcgga taaggaccta
    16141 gaaacagcgc gtgaattgca gtatgctatc aacgcaatca ttggtaaact cacttctgct
    16201 catggaaata tgtacggtgt cattaaagaa gtcttgaaaa tcaatgaagg cttgaatatt
    16261 ggatctgttc gttcaccatt gacaccagtg actgaagaag atcgtccagt tgtagaagcg
    16321 gctgctgcct tgattcgtga aaccaaggag cgcttcctct aatataaaag gaggtattta
    16381 tgacatacta cgttgcaatt gatatcggtg gaaccaacat caagtatggt ttggttgatc
    16441 aagaggggca acttcttgaa tcgcatgaaa tgccaactga ggcgcataag ggtggacctc
    16501 atatcttaca aaagaccaaa gatatcgtag ctagttattt agaaaaaggc ccagtagcag
    16561 gtgttgccat atcttctgct gggatggtgg atccggataa gggtgagatt ttctatgctg
    16621 ggcctcaaat ccctaactac gcaggcaccc agttcaaaaa ggaaatcgaa gaaagcttta
    16681 ctattccttg tgagattgaa aatgatgtca actgtgcagg tcttgctgag gcagtatctg
    16741 gttcaggcaa gggagcaagt gtgacacttt gcttgaccat tggaaccggt atcggtggtt
    16801 gcttgattat ggataggaaa gtcttccatg gttttagcaa ttcagcctgt gaagtcgggt
    16861 atatgcatat gcaggatgga gcttttcagg atctcgcttc tacaacagct ttagtgaaat
    16921 atgtagctga agcccatgga gaagatgttg atcagtggaa tggccgacgt atctttaagg
    16981 aagctactga aggaaacaaa atctgcatgg aaggtattga ccgtatggtt gactatctag
    17041 gaaaaggtct ggcaaatatt tgttatgtgg ccaatccaga agtggttatt cttggtggtg
    17101 gtatcatggg gcaagaggct atcctcaaac ctaagatccg cacagccttg aaagaggcat
    17161 tggtaccaag tttagcagaa aaaacacgat tagaatttgc ccatcaccaa aatacagcag
    17221 ggatgttggg tgcatattat cattttaaga caaaacaatc ctagtttggc tcagccaaac
    17281 taggattttc ttacacgttt ttgtctacga tagccgttga gttttttatt ttcccagtag
    17341 ctattaaaga ttttttcctt gctttcgcga ttgatttcca aaaagtaggc ataaatcaaa
    17401 tcgataaaga agagcatagg aagttgagcg gatattcgtt ggatgtagga gggttggctg
    17461 tgggtggcta caagaacagt ctctgtatag gtctggctat ctttattggg aacacttgta
    17521 aagagtacag tctttgcccc catctccttg gcatctaata gactatctaa aatagaagga
    17581 gttgagcctg aaagtgagaa acccagtact agacaatttt catccatgat gctggttgtc
    17641 caggcaaagc cgtcttggtc tgtcaaagct tcgcagacca cacctagtcg cataaaacgt
    17701 aatttcattt cacgggcgac gaggccagaa ctccctgttc caaagaagta gatacgctca
    17761 gcatcttcga ttagctgggc aattcgctct agttggattt cgtcaatcaa gtcttgtgtt
    17821 tgttccctca tgttgctata acttctgagg actcgtttgg tcagtggact gtgcttggaa
    17881 acttggttgg cttgattttc tgcctgatgt tggtattgga aaataaattc tcggtagcca
    17941 gtaaagccac actttttagc aaagcgggtc aaagcagctt gagaaatatg taatttttgg
    18001 gtgacttgtt gagaagataa atcatctgta atcgtttcag cttgcaaaaa atagcgagcg
    18061 atttcttgct ctaggtctgt catttcttca aaatgtgaat caatgatagt tgcgatatct
    18121 ggtttgtcca tagggaaagc tcctttacat gagtcatact ggaagactag atcagggaat
    18181 agtcacactt cattataaca cataatataa ggatagataa ataaaaacgc atctctgttt
    18241 taaaaacgaa aaaatcgaaa aagcttctct cttttccata attttctact caaattgtgg
    18301 tacaattaag agtaagattt taagttagaa atgagactga tttgtatgag aaaatttaac
    18361 agccattcga ttccgattcg gcttaattta ttgttttcaa tcgtcatttt actctttatg
    18421 gccattattg gtcgtttgtt gtatatgcag gttttgaaca aggattttta cgaaaaaaag
    18481 ctagcctcag ctagtcagac caagattaca agcagttcag cccgtgggga aatttatgat
    18541 gctagtggaa aacctttggt agaaaatacg ttaaagcagg ttgtttcctt tacgcgtagc
    18601 aataaaatga cggctacaga cttaaaagaa acagctaaaa agttactgac ttatgtgagc
    18661 atcagttctc caaatttgac agaacgccag ctggcggatt actatttggc tgatcctgaa
    18721 atctataaaa aaacagtgga agctctccca agcgagaaac gcttggattc agatggcaat
    18781 cgtctatccg aatcagaact gtataacaat gcggtcgata gtgtacaaac gagtcaacta
    18841 aactatacag aggatgaaaa gaaagaaatc tatcttttta gtcagttaaa tgctgttgga
    18901 aactttgcga caggaaccat tgcgacagat cctctaaatg attctcaggt ggctgttatt
    18961 gcctctattt caaaggagat gcctggcatt agtatttcta cttcttggga tagaaaggtt
    19021 ttggaaactt ccctttcttc tatagttggg agtgtatcca gtgaaaaagc tggtctccca
    19081 gcggaagaag cagaagccta tcttaaaaaa ggctattctc taaatgatcg tgtaggaacc
    19141 tcctatttgg aaaagcaata tgaagagacc ttacaaggaa aacgctcggt aaaagaaatc
    19201 catctggata aatatggcaa tatggaaagc gtggatacaa ttgaggaagg tagtaaggga
    19261 aacaatatca aactgaccat tgatttggct ttccaagata gcgtggatgc tttactgaaa
    19321 agttatttca attccgagct agaaaatggt ggagccaagt attctgaagg tgtctatgca
    19381 gtcgccctta acccaaaaac aggtgcggtt ttgtctatgt cagggattaa acatgacttg
    19441 aaaacgggag agttgacgcc tgattccttg ggaacggtaa ccaatgtctt tgtgccgggt
    19501 tctgttgtca aggcggcgac catcagctct ggttgggaga atggagtctt atcagggaat
    19561 cagaccttga cagaccaacc gattgtcttc caaggttcag ctccgattaa ttcttggtac
    19621 actcaggctt acggttcatt cccgattaca gctgtggaag ccttggagta ttcttctaat
    19681 gcctatatgg ttcaaacggc tttgggcatt atgggtcaga cctatcaacc caatatgttt
    19741 gttctaacta acaatttaga atccgccatg gggaaacttc gctcgacatt tgcggaatat
    19801 ggtcttggag cctcaacagg cattgacctt ccagatgagt caactggttt tataccaaaa
    19861 gagtataatt ttgctaatta cattaccaat gcctttggtc agtttgataa ctacactcct
    19921 atgcaattgg cccagtacgt tggaaccatt gccaacaacg gtgttcggat tgcacctcac
    19981 attgtcgagg ggatttatgg aaacaatgaa caaggcggct tagggaactt aatccaatct
    20041 gttgaatcca aggaaatgaa taaaattaat atttctgagt ctgatgtttc catcctccaa
    20101 caaggctttt atcaagtgtc acatggtggt agtgctttga caaccggtcg tgccttttca
    20161 aatggcgcaa gcgtatcgat tagtggtaaa acaggtactg ccgaaagtta tgttgagggt
    20221 ggtcaagaag ctaacaatac taatgctgtg gcctatgcac catcagataa tcctcaaatc
    20281 gctgtagctg ttgtcttccc tcataacacc aaccttacaa atggtgtcgg accttccatt
    20341 gcgcgcgata ttatcaacct ctataaccaa catcatccaa tgaattagaa aggaacatat
    20401 gctttatcca acacctattg ctaagctaat tgacagttat tctaagttac cgggtatcgg
    20461 gattaagacg gctacacgtc tggccttcta tactattgga atgtctgatg acgatgtcaa
    20521 tgaatttgct aaaaatctcc tttctgctaa gagagagctg acctactgtt ccatctgcgg
    20581 tcgcctgact gatgacgatc cttgctctat ctgtaccgat ccgactcgtg accagacaac
    20641 gattttagtt ctcgaagata gtcgcgatgt ggcagccatg gagaatatcc aagaatacca
    20701 tggactctat catgtcttgc atggactcat ttctcccatg aatggtatta gtccagatga
    20761 tatcaatctc aagagcctca tgactcgtct tatggatagt gaagtttcag aggtaatcgt
    20821 agcaacaaat gctacagcag atggtgaagc gacatccatg tatctttcac gtttgctcaa
    20881 gccagctggt atcaaggtta cgcgtctagc acgaggtctc gctgtcggag cggacattga
    20941 gtatgcggat gaagtgacgc tcttacgagc cattgaaaat cgaacagagt tgtaagtgta
    21001 ggcaaattta cgaactccat tcatttataa aaaatcaaag aggctgaaaa tcgttcctat
    21061 cggcctcttt ttgtatagtg tgatgagtag gatcaggttc aagttttaaa aaaccaagca
    21121 aatatgatat actaaagagc gagtattcta gtagaattag gacgaataat atgaaacaaa
    21181 cgattattct tttatatggt ggacggagtg cggaacgcga agtctctgtc ctttcagctg
    21241 agagtgtcat gcgtgcggtc gattacgacc gtttcacagt caagactttc tttatcagtc
    21301 agtcaggtga ctttatcaaa acacaggaat ttagtcatga tccggggcaa gaagaccgtc
    21361 tcatgaccaa tgaaaccatt gattgggata agaaagttgc accaagtgct atctacgaag
    21421 aaggtgcagt ggtctttcca gtccttcacg ggccaatggg agaagatggc tctgttcaag
    21481 gattcttgga agttttgaaa atgccttacg ttggttgcaa cattttgtca tcaagtcttg
    21541 ccatggataa aatcacgact aagcgtgttc tggaatctgc tggtattgcc caagttcctt
    21601 atgtggctat cgttgaaggc gatgatgtga ctgctaaaat cgctgaagtg gaagaaaaat
    21661 tggcttatcc agtcttcact aagccgtcaa acatggggtc tagtgtcggt atttctaagt
    21721 ctgaaaacca agaagaactc cgtcaagcct tagaacttgc cttccgatat gatagccgtg
    21781 tcttggttga gcaaggagtg aatgcccgtg aaattgaggt tggcctcttg ggtaactacg
    21841 atgtcaagag cacgctacca ggagaagttg tcaaggatgt tgccttttat gactacgatg
    21901 ccaagtatat tgataacaag attactatgg atattcctgc caaaatcagt gatgatgtgg
    21961 tggctgtcat gcgtcaaaat gcagaaacag ccttccgtgc cattggtggc cttggtctat
    22021 ctcgttgcga tttcttctat acagataagg gagagatttt tctcaacgag ctcaatacca
    22081 tgccaggttt cacccagtgg tctatgtacc cactactttg ggacaatatg gggatcagct
    22141 acccagaact aatcgagcgt ttggttgacc ttgccaagga aagttttgac aagcgcgaag
    22201 cgcatttgat ataaaatgaa agagagggta gaagccagaa ccatcactgc acggtgacta
    22261 gagttctcgg acttcagccc tttttaaagg agtagaaatg aaattaacaa tccatgaaat
    22321 tgcccaagtt gttggagcca aaaatgatat cagtatcttt gaggacaccc agttagaaaa
    22381 agctgagttt gatagtcgtt tgattggaac tggagattta tttgtgccac ttaaaggtgc
    22441 gcgtgatggc catgacttta ttgaaacagc ctttgaaaat ggtgcagcag taaccttgtc
    22501 tgagaaagag gtctcaaatc atccttacat tctagtagat gatgttttga cagcctttca
    22561 atccctagca tcctactatc ttgaaaaaac gactgttgat gtctttgctg ttacaggttc
    22621 aaatggcaag acaacgacta aggatatgtt ggcgcattta ctgtcaacaa gatacaagac
    22681 ctacaaaaca caaggcaatt acaataacga gattggcctt ccttacacag ttcttcatat
    22741 gcctgaaggg acagaaaagt tggtcttgga gatggggcag gatcacttgg gagatattca
    22801 tctcttgtct gaattggctc gtccaaaaac agccatcgtg accttggttg gagaagccca
    22861 tttggccttt ttcaaagacc gttcagagat tgctaaggga aaaatgcaaa ttgcagacgg
    22921 aatggcttca ggttccttgc ttttagcgcc ggctgaccct atcgtagagg actatttgcc
    22981 aactgataaa aaggtggttc gttttggtca aggagcagag ctggaaatta ctgacttggt
    23041 tgagcgcaaa gatagtctga ccttcaaggc caatttctta gagcaagtcc ttgatttgcc
    23101 agtgactggc aagtacaatg cgacaaatgc tatgattgca tcctatgttg ccttgcaaga
    23161 aggagtttca gaggagcaaa ttcatcaggc cttccaaggt cttgaattga cgcgtaatcg
    23221 tactgagtgg aagaaagcag ccaatggagc agatatcctg tcagacgtat ataatgccaa
    23281 tccaactgct atgaagctga ttttagagac tttctctgcc attccagcca atgaaggtgg
    23341 caagaaaatt gcagtgttgg cggatatgaa ggagcttggt gaccagtcta ttcaactcca
    23401 taaccagatg attttgagcc tttctccaga tgtgcttgat accgttattt tctatggaga
    23461 aaatattgct gaattagccc aattggctag tcaaatgttc ccaataggcc acgtttacta
    23521 cttcaagaaa acagaagacc aagaccaatt tgaagaccta gtcaagcagg tcaaagaaag
    23581 ccttggagtc cacgaccaaa tcctgctcaa aggctctaac tctatgaatc tagccaagtt
    23641 ggtagaaagt ttagaaaatg aaaccaagtg attttgttaa gtatctgcaa agaatgattg
    23701 cccttacaga tactggctta acctttacaa aagatccttt tgaccgtgag cgctacgaag
    23761 acttgcgaag tctgttatct gaaatgttga atcaggtatc agacctggat gcagaagaag
    23821 tagcagaagt cttgaaacca acttcagctt atgcgactcc cttaatggac gtccgtgctt
    23881 ggattgttga ggatgagaag atttgtctgg ttaggggaca aggagaggat agttgggctt
    23941 tgccaggtgg ctttggtgaa gtcggctatt ctccaactga aaatattctc aaggaaattg
    24001 aagaagaaac cggttttaaa gccaaagttg aaagactgct agctgttttt gataccaatc
    24061 gtttccaact acagagcaaa caatatgcaa agtttgtttt tgaatgtaag cttctcgatg
    24121 gacaattcca agaaaatcaa gaaatcgctg cccttcaatt ttttgcaatt gaccaactgc
    24181 cgaatttatc tgaaaaacgc attaccaagg agcaaatcga gattctttgg caggtttatc
    24241 aaggtcagag ggagcaatat cttgactaag aagatgatta tcgtatttct aaatccattt
    24301 ttgacaacta gcatggtata ataatatgca ggaaaatttt gaatcatgag gaagactaga
    24361 tgaatttatg ggatattttc tttacgactc aggcaaccga gccgcccaaa tttgaccttt
    24421 tttggtatgt tagcctattt acgctcttag ccttaacctt ttatacagcc catcgctatc
    24481 gtgaaaagaa ggtttaccaa cgatttttcc aaatcttgca gactgttcag ttaatccttc
    24541 tttatggttg gtactgggtc aatcatatgc cactgtcaga aagcctaccc ttttaccatt
    24601 gccgtatggc tatgtttgtg gtactcttgc ttcctggtca gtccaaatat aaacaatact
    24661 ttgcattatt gggaacattt gggacattag cagcctttgt ttatccagtg ccagatgctt
    24721 acccttttcc acatatcacc attctatcct ttatctttgg tcatttagca ctcttgggga
    24781 actctctagt ttatctattg agacagtata atgcgcgatt gctggatgtg aagggaattt
    24841 ttctcatgac ctttgcccta aatgccttga tttttgtggt caatttggtg acaggtggcg
    24901 attacggatt tttgacaaaa ccgccattgg ttggggatca cggtctagta gctaattatt
    24961 tacttgtttc aattgtgctg gtagctacta tcagtttgac taagaaaatc ttagaattct
    25021 ttttagctca agaagcagaa aaaatgattg caaaggaagc ttaacacaga gctttctttt
    25081 ttgctcttag agagttttta caagcagctt ataaaataag aatttctgaa tagacaaact
    25141 caaaaaatgg ctgggaaatt taggaaaaaa gcaagcacga ttaaattttt tgtgttataa
    25201 tattttgtga atagctatgc ctatgtttag ctatggaata atacgaagtg cgaaacttgg
    25261 aagatagaga ggaagcgatg taatggctag agaaggcttt tttacaggtc tagatattgg
    25321 aacaagctct gtcaaggtgc ttgtggccga gcagagaaat ggtgaattaa atgtaattgg
    25381 cgtgagtaat gccaaaagta aaggtgtaaa ggatggaatt attgttgata ttgatgcagc
    25441 agcaactgct atcaagtcag ccatttccca agcggaagaa aaggcaggca tttcgattaa
    25501 atcagtaaat gtcggcttgc ctggtaatct tttgcaggta gaaccaactc aggggatgat
    25561 tccagtaaca tctgatacta aggaaattac ggatcaagat gttgaaaatg ttgtcaaatc
    25621 agctttgaca aagagtatga cacctgaccg tgaagtcatt acctttattc ctgaagaatt
    25681 tattgtggat ggtttccaag ggattcgtga cccacgtggc atgatggggg ttcgccttga
    25741 aatgcgtggt ttgctttata caggacctcg tactatcttg cacaatttgc gtaagacggt
    25801 tgagcgtgca ggtgttcagg ttgaaaatgt tatcatttca ccactagcaa tggttcagtc
    25861 tgttttgaac gaaggggaac gtgaatttgg tgctacagtg attgatatgg gggcaggtca
    25921 aacgactgtc gctacaatcc gtaatcaaga actccagttc acacatattc tccaagaagg
    25981 tggagattat gtaactaaag atatctccaa ggttttgaaa acctctcgca aattagcgga
    26041 aggcttgaaa ctgaattacg gggaagccta tccgcctctt gcaagcaaag aaaccttcca
    26101 agtagaggtt attggagaag tagaagcagt cgaagtgacg gaagcctact tgtcagaaat
    26161 tatttctgca cgaatcaagc acatccttga acaaatcaag caagaattag atagaaggcg
    26221 tctattggac ctccctggtg gtattgtctt aatcggtggg aatgccattt taccaggtat
    26281 ggttgagctt gctcaggaag tctttggcgt ccgtgtcaag ctttatgttc caaatcaagt
    26341 tggtatccgt aatccagcct ttgcgcatgt gattagttta tcagaatttg cgggtcaatt
    26401 aacagaagtt aatcttttgg ctcagggagc gataaaaggt gagaatgact taagtcatca
    26461 gccaattagt tttggtggga tgctgcaaaa aacagctcag tttgtacaat caacgcctgt
    26521 tcaaccagct cctgctccag aagtagagtc ggtggcgcct acagaaccaa tggcggattt
    26581 ccaacaagct tcacaaaata aaccgaaatt agcagatcgt ttccgtggct tgatcggaag
    26641 catgtttgac gaataaagag gaaaaataaa ttatgacatt ttcatttgat acagctgctg
    26701 ctcaaggggc agtgattaaa gtaattggtg tcggtggagg tggtggcaat gccatcaacc
    26761 gtatggtcga cgaaggtgtt acaggcgtag aatttatcgc agcaaacaca gatgtacaag
    26821 cattgagtag tacaaaagct gagactgtta ttcagttggg acctaaattg actcgtggtt
    26881 tgggtgcagg aggtcaacct gaggttggtc gtaaagccgc tgaagaaagc gaagaaacac
    26941 tgacggaagc tattagtggt gccgatatgg tcttcatcac tgctggtatg ggaggaggct
    27001 ctggaactgg agctgctcct gttattgctc gtatcgccaa agatttaggt gcgcttacag
    27061 ttggtgttgt aacacgtccc tttggttttg aaggaagtaa gcgtggacaa tttgctgtag
    27121 aaggaatcaa tcaacttcgt gagcatgtag acactctatt gattatctca aacaacaatt
    27181 tgcttgaaat tgttgataag aaaacaccgc ttttggaggc tcttagcgaa gcggataacg
    27241 ttcttcgtca aggtgttcaa gggattaccg atttgattac caatccagga ttgattaacc
    27301 ttgactttgc cgatgtgaaa acggtaatgg caaacaaagg gaatgctctt atgggtattg
    27361 gtatcggtag tggagaagaa cgtgtggtag aagcggcacg taaggcaatc tattcaccac
    27421 ttcttgaaac aactattgac ggtgctgagg atgttatcgt caacgttact ggtggtcttg
    27481 acttaacctt gattgaggca gaagaggctt cacaaattgt gaaccaggca gcaggtcaag
    27541 gagtgaacat ctggctcggt acttcaattg atgaaagtat gcgtgatgaa attcgtgtaa
    27601 cagttgttgc aacgggtgtt cgtcaagacc gcgtagaaaa ggttgtgtct ccacaagcta
    27661 gaactgctac taactaccgt gagacagtga aaccagctca ttcacatggc tttgatcgtc
    27721 attttgatat ggcagaaaca gttgaattgc caaaacaaaa tccacgtcgt ttggaaccaa
    27781 ctcaggcatc tgcttttggt gattgggatc ttcgccgtga atcgattgtt cgtacaacag
    27841 attcagtcgt ttctccagtc gagcgctttg aagccccaat ttcacaagat gaagatgaat
    27901 tggatacacc tccatttttc aaaaatcgtt aagtaaatga atgtaaaaga aaatacagaa
    27961 cttgtttttc gagaagttgc agaggctagt ctgagtgctc atcgagagag tggttcggtc
    28021 tctgtcattg cagttaccaa gtatgtagat gtaccgacag cggaagcctt gcttccgcta
    28081 ggtgttcatc atatcggtga aaatcgtgta gataagtttc tggaaaaata tgaagcttta
    28141 aaagatcgag atgtgacttg gcatttgatt ggtaccttgc aaagacgtaa ggtgaaagat
    28201 atcattcaat acgttgatta tttccatgca ttggactcag taaagctagc aggggaaatt
    28261 caaaaaagaa gtgaccgagt catcaagtgt ttccttcaag taaatatttc taaagaagaa
    28321 agcaaacacg gtttttcgag agaggaactg ctggaaatct tgccagagtt agccagacta
    28381 gataagattg aatatgttgg tttaatgacg atggcacctt ttgaggctag cagtgagcag
    28441 ttgaaagaga ttttcaaggc ggcccaagat ttacaaagag aaattcaaga gaaacaaatt
    28501 ccaaatatgc ctatgaccga gttaagtatg ggaatgagtc gtgattataa agaagcgatt
    28561 caattcggtt ccacttttgt tcgtataggt acatcatttt ttaagtagga gagaaccatg
    28621 tctttaaaag atagattcga tagatttata gattatttta cggaggatga ggattcaagt
    28681 ctcccttatg aaaaaagaga tgagcctgtg tttactccag taaattcttc acaggaaccg
    28741 gctctcccaa tgaatcaacc ttcacagtcg gctggtacaa aagagaacaa tatcaccaga
    28801 cttcatgcaa gacaacagga attggcaaat cagagtcagc gtgcaacgga taaggtcatt
    28861 atagatgttc gttatcctag aaaatatgag gatgcaacag aaattgttga tttattggca
    28921 ggaaacgaaa gtatcttgat tgattttcag tatatgacag aggtgcaggc tcgtcgttgt
    28981 ttggactatt tggatggagc ttgtcatgtt ttagctggaa atttgaaaaa ggtagcttct
    29041 accatgtatt tgttgacacc agtgaatgtt attgtaaatg ttgaagatat ccgtttacca
    29101 gatgaagatc aacagggtga gttcggtttt gatatgaagc gaaatagagt acgataatga
    29161 tttttttaat tcgtatgatt tataatgcag tggatattta ctccctgatt ttggtagcct
    29221 tcgctgtcat gtcttggttt ccaggtgcct acgaatccag tttaggtcgt tggattgtag
    29281 cgttggtgaa accagtgctt gctcccttgc aacgcctgcc tttacagata gcgggtcttg
    29341 atttatctgt ttgggttgcg attgttttgg ttcgattttt aggagaaaac ctagtgcgtt
    29401 ttctggcgat gataggatga ataaagggat ttatcagcat ttctccatag aagatcgtcc
    29461 atttcttgac aagggaatgg aatggataaa gaaggtagaa gatagctatg ctcctttttt
    29521 aactcctttt atcaatcctc atcaggagaa gctattaaag attttggcca aaacctatgg
    29581 tcttgcttgt agcagtagtg gggaattcgt ctcgagtgag tatgttcgag ttttattata
    29641 cccagattat ttccaaccag agttttcaga ttttgaaata tctctccagg aaattgtgta
    29701 ttccaataaa tttgaatatt taacgcatgc taagatttta gggacagtca tcaatcaatt
    29761 agggattgaa cggaaacttt ttggagatat cctagtagat gaagaacggg cgcagattat
    29821 gattaatcag cagtttcttc ttctctttca agatggacta aagaaaattg gtcgtatacc
    29881 tgtttcgctg gaggaacgtc ctttcaccga gaaaatagat aagctagaac agtatcgaga
    29941 actggattta tctgtgtcta gttttcgatt agatgttctt ttatcaaatg ttttgaaact
    30001 atctaggaat caagcaaacc agttgattga aaagaaactt gtccaagtaa attatcatgt
    30061 ggtagacaaa tcagattaca ctgttcaagt tggagacttg attagtgtga gaaaatttgg
    30121 tcgcttgaga ttacttcaag ataagggaca aacgaaaaaa gagaagaaaa aaataaccgt
    30181 ccagttatta ttaagtaagt gaggaataga atgccaatta catcattaga aataaaggac
    30241 aagacttttg gaactcgatt cagaggtttt gatccagaag aagtcgatga atttttagat
    30301 attgtggttc gtgattacga agatcttgtg cgtgcgaatc atgataaaaa tttgcgtatt
    30361 aagagtttag aagagcgttt gtcttacttt gatgaaataa aagattcatt gagccagtct
    30421 gtattgattg cccaggatac agctgagcga gtgaaacagg cggcgcatga acgttcaaac
    30481 aatatcattc atcaagcaga gcaagatgcg caacgcttgt tggaagaagc taaatataag
    30541 gcaaacgaga ttcttcgtca agcaactgat aatgctaaga aagtcgctgt tgaaacagaa
    30601 gaattgaaga acaagagccg tgtcttccac caacgtctca aatctacaat tgagagtcag
    30661 ttggctattg ttgaatcttc agattgggaa gatattctcc gtccaacagc tacttatctt
    30721 caaaccagtg atgaagcctt taaagaagtg gttagcgaag tacttggaga accgattcca
    30781 gttccaattg aagaagaacc aattgatatg acacgtcagt tctctcaagc agaaatggaa
    30841 gaattacaag ctcgtattga ggtagccgat aaagaattgt ctgaatttga agctcagatt
    30901 aaacaggaag tggaagctcc aactcctgta gtgagtcctc aagttgaaga agagcctctg
    30961 ctcatccagt tggcccaatg tatgaagaac cagaagtagc tccagtgcat ccgacaggtc
    31021 caacaccagc tacagaaact gttgattcag caccgggatt tgaagcaccg caagaatctg
    31081 ttacaatttt ataagaaata ttctgagaac aatatcttat ccttatattc ccagcgagca
    31141 ggagatggtg tgagtcctgc attccctatc gataagatta tcctctcaaa aactcaagtc
    31201 tgaatctagt aagatttgac gttccccacg ttacgggata agagggagaa agactaaaac
    31261 tttttccgaa taaaggtggt accacgattt tcgtcctttt tggaagtcgt ggtttttaat
    31321 ttgttattat ttataaagga gataccatga aactcaaaga cacccttaat cttgggaaaa
    31381 ctgaattccc aatgcgtgca ggccttccta ccaaagagcc agtttggcaa aaggaatggg
    31441 aagatgcaaa actttatcaa cgtcgtcaag aattgaacca aggaaaacct catttcacct
    31501 tgcatgatgg ccctccatac gctaacggaa atatccacgt tggacatgct atgaacaaga
    31561 tttcaaaaga tattattgtt cgttctaagt ctatgtcagg attttacgca ccatttattc
    31621 ctggttggga tactcatggt ctgccaatcg agcaagtatt gtcaaaacaa ggtgtcaaac
    31681 gtaaagaaat ggacttggtt gagtacttga aactttgccg tgagtacgct ctttctcaag
    31741 tagataaaca acgtgaagat tttaaacgtt tgggtgtttc tggtgactgg gaaaatccat
    31801 atgtgacctt gactcctgac tatgaagcag ctcaaattcg tgtatttggt gagatggcta
    31861 ataagggtta tatctaccgt ggtgccaagc cagtttactg gtcatggtca tctgagtcag
    31921 cccttgctga agcagagatt gaataccatg acttggtttc aacttccctt tactatgcca
    31981 acaaggtaaa agatggcaaa ggagttctag atacagatac ttatatcgtt gtctggacaa
    32041 cgactccatt taccatcaca gcttctcgtg gtttgacggt tggtgcagat attgattacg
    32101 ttttggttca acctgctggt gaagctcgta agtttgtcgt tgctgctgaa ttattgacta
    32161 gcttgtctga gaaatttggc tgggctgatg ttcaagtttt ggaaacttac cgtggccaag
    32221 aactcaacca catcgtaaca gaacacccat gggatacagc tgtagaagag ttggtaattc
    32281 ttggtgacca cgttacgact gactctggta caggtattgt ccatacagcc cctggttttg
    32341 gtgaggacga ttacaatgtt ggtattgcta ataatcttga agtcgcagtg actgttgatg
    32401 aacgtggtat catgatgaag aatgctggtc ctgaatttga aggtcaattc tatgaaaagg
    32461 tagttccaac tgttattgaa aaacttggta acctccttct tgcccaagaa gaaatctctc
    32521 actcatatcc atttgactgg cgtactaaga aaccaatcat ctggcgtgca gttccacaat
    32581 ggtttgcctc agtttctaaa ttccgtcaag aaatcttgga cgaaattgaa aaagtgaaat
    32641 tccactcaga atggggtaaa gtccgtcttt acaatatgat ccgtgaccgt ggtgactggg
    32701 ttatctctcg tcaacgtgct tggggtgttc cacttcctat cttctacgct gaagatggta
    32761 cagctatcat ggtagctgaa actattgaac acgtagctca actttttgaa gaacatggtt
    32821 caagcatttg gtgggaacgt gatgccaaag acctcttgcc agaaggattt actcatccag
    32881 gttcaccaaa cggcgagttc aaaaaagaaa ctgatatcat ggacgtttgg tttgactcag
    32941 gttcatcatg gaatggagtg gtggtaaacc gtcctgaatt gacttaccca gccgaccttt
    33001 acctagaagg ttctgaccaa taccgtggtt ggtttaactc atcacttatc acatctgttg
    33061 ccaaccatgg cgtagcacct tacaaacaaa tcttgtcaca aggttttgcc cttgatggta
    33121 aaggtgagaa gatgtctaaa tctcttggaa ataccattgc tccaagcgat gttgaaaaac
    33181 aattcggtgc tgaaatcttg cgtctctggg taacaagtgt tgactcaagc aatgacgtgc
    33241 gtatctctat ggatatttta agccaagttt ctgaaactta ccgtaagatt cgtaacactc
    33301 ttcgtttctt gattgccaat acatctgact ttaacccagc tcaagataca gtcgcttacg
    33361 atgagcttcg ttcagttgat aagtacatga cgattcgctt taaccagctt gtcaagacca
    33421 ttcgtgatgc ctatgcagac tttgaattct tgacgatcta caaggccttg gtgaacttta
    33481 tcaacgttga cttgtcagcc ttctaccttg attttgccaa agatgttgtt tacattgaag
    33541 gtgccaaatc actggaacgc cgtcaaatgc agactgtctt ctatgacatt cttgtcaaaa
    33601 tcaccaaact cttgacacca atccttcctc acactgcgga agaaatttgg tcatatcttg
    33661 agtttgaaac agaagacttc gtccaattgt cagaattacc agaagttcaa acttttgcta
    33721 accaagaaga aatcttggat acatgggcag ccttcatgga ctttcgtgga caagcacaaa
    33781 aagccttgga agaagctcgt aatgcaaaag ttatcggtaa atcacttgaa gcacacttga
    33841 cagtttatcc aaatgaagtg gtgaaaactc tactcgaagc agtaaacagc aatgtagctc
    33901 aacttttgat cgtgtctgag ttgaccatcg cagaaggacc agctccggaa gctgccctta
    33961 gcttcgaaga tgtagccttc acagttgaac gtgctgctgg tgaagtatgt gaccgttgcc
    34021 gtcgtattga cccaacaaca gcagaacgca gctaccaggc agttatctgt gaccactgtg
    34081 caagcatcgt agaagaaaac tttgcggaag cagtcgcaga aggatttgaa gagaaataag
    34141 attgaaaagt ctaggcaaaa ttcaatttga gaagaaaaga caactaattt tatagtctat
    34201 taaacgcatt gtatcacgtt tttgaacacc tgatacgatg cgtttttatt tattttgaaa
    34261 atttgtgagg tgtgactttt tatactcaac aagaatcaaa gagaaactta gcaagctaac
    34321 agtagtaaga taaaatagga atttgatatt agggataaga ttggtaaata gtgtaatatt
    34381 tttacaacaa taaatttata tagttatttc tggttgctga aaagtattat attatatttt
    34441 atttcatatt atacaaattt ttattttata atatcagaaa atactttttt aaaaaagcaa
    34501 atatgataca attttatttg aaaaaaaata aaaaaggaga ttttattatg aaatcaaaaa
    34561 gacttgcttt aattagtggt atcgtcggtc ttgtgggagg aattttactt cttatttgtc
    34621 cttttgtctt gttgggaaca gcggtaaata cagctgctac aactcttaat ggaggagcta
    34681 ctgcaggggc tttttcaggt gttgccttac tcttgaatgc cttgaagatt gcaaatcttg
    34741 ttcttggtat cattgctatt gtttactata aaggagataa gcatgtaggt gcagctccgt
    34801 ctgtactaat gattgtttct ggtgaagtta gtctcattcc attcttagga tgggttgggg
    34861 ggattcttgc tattatcgga ggatctctat tccttgcaac attgaagaaa ttcaaatcag
    34921 aagaataaaa ggtattttag catgaaaaga ataaaaacgt ttatcggtat aggagtagct
    34981 ctattatctc tttctcttct agttgcatgt ggaacataaa gttcaaagaa tacttcaaca
    35041 agtaatgatg agaagacagt agcaacatcc aatagttcaa aagaaacaat cactttcgat
    35101 acaccggttg taacagacga tgcgattgaa tcaatacgca cttatgcaga ttatatagat
    35161 ctttataaaa atatttttga tgattatttt actaaaactg aggaaggttt caaaggcaca
    35221 gttatggaaa ataatgactc gtttactaaa ctaaaagagt caactcaaaa attattcgat
    35281 gcgcagaaaa aaaggttaaa taatgaagat agaatagaaa caaccaaaaa caatgtgatt
    35341 gccaaacatt gtcaaacagt cctttccttt ttggttttga ctagcttttt tgtgaaaaat
    35401 tgtgtaaaat agaatagata aacgagggga aacctcggaa aatttaaagg agaatccatc
    35461 taatggtaaa attggttttt gctcgccacg gtgagtctga atggaacaaa gctaaccttt
    35521 tcactggttg ggctgatgtt gatttgtctg aaaaaggtac acaacaagcg attgacgctg
    35581 gtaaattgat caaagaagct ggtatcaaat ttgaccaagc ttacacttca gtattgaaac
    35641 gtgctatcaa aacaactaac ttggctcttg aagcttctga ccaattgtgg gttccagttg
    35701 aaaaatcatg gcgcttgaac gaacgtcact acggtggttt gactggtaaa aacaaagctg
    35761 aagctgctga acaatttggt gatgagcaag ttcacatctg gcgtcgttca tacgatgtat
    35821 tgcctccaaa catggaccgt gatgatgagc actcagctca cacagaccgt cgttacgctt
    35881 cacttgacga ctcagttatt ccagatgctg aaaacttgaa agtgactttg gaacgtgctc
    35941 ttccattctg ggaagataaa atcgctccag ctcttaaaga tggtaaaaac gtattcgtag
    36001 gagctcacgg taactcaatc cgtgcccttg taaaacacat caaaggtttg tcagatgacg
    36061 agatcatgga cgtggaaatc cctaacttcc caccattggt attcgaattc gacgaaaaat
    36121 tgaacgtcgt ttctgaatac taccttggaa aataaaaaat tgtaagtcta gaattgattt
    36181 ctaggctttt tatgttagta tggaagtatg ataaggaata aaaaacaaga ttatgtactg
    36241 gcctacaagc aaccagcttc aaccacttac atgggttggg aagaagaagc tttaccgata
    36301 ggcaatggtt ctttaggagc aaaagtattt ggccttatag gggctgaacg gattcaattt
    36361 aatgaaaaaa gtctctggtc tggaggtcca cttcctgata gttcagatta tcagggtgga
    36421 aatcttcagg atcagtatgt ttttttggct gagattcggc aggctttgga gaagagagat
    36481 tacaatctgg ctaaggaact ggctgagcag cacctaattg ggccaaaaac gagtcaatat
    36541 gggacctatc tgtcttttgg ggatattcac attgagttca gccagcaagg tacgactttg
    36601 tctcaggtga cggactatca gagacagctg aatattagta aggcacttgc gacgacttct
    36661 tatgtctata agggaacgcg atttgaacgt aaagcttttg cgagttttcc agatgatctc
    36721 ttggttcaat gttttactaa ggaagggttg gaaactctag attttactat agaactatcc
    36781 ttgacctgtg atttggcttc tgatggaaag tatgagcagg aaaaatctga ttacaaggag
    36841 tgtaagttgg atattactga ttctcatatc ttgatgaagg gaagagttaa ggataatgat
    36901 ctgcggtttg ctagttatct agcttgggaa acggatggag atattagagt ttggtcagat
    36961 agggttcaga tatcaggagc cagttatgcc aatctcttct tggccgctaa gacggatttt
    37021 gcccaaaatc ctgctagcaa ttatcgcaag aaactagatt tagagcaaca ggtgatagac
    37081 ttggtggaca cagctaaaga aaagggctat acccaattga aatcaaggca tatcgaggac
    37141 taccaagcct tattccagcg tgttcaattg gatttggaag ctgatgttga cgcatccact
    37201 acagatgatt tgttaaaaaa ttataagcca caagaagggc aggctttgga ggagctgttc
    37261 ttccagtatg gacggtattt attgattagt tcgtccagag actgcccaga tgctctacca
    37321 gctaacctac agggagtctg gaatgcagtc gacaatcctc cttggaattc ggactatcac
    37381 ttaaatgtca atctgcagat gaattattgg ccagcctatg ttaccaatct cctagaggcg
    37441 gtctttccgg tcatcaacta tgtagatgat ttgcgtgtct atggtcgtct agcggctgta
    37501 aagtatgcag gaatcgtctc tcagaaaggt gaggagaatg gttggttggt tcatactcaa
    37561 gcgactccct ttggttggac ggcacctggt tgggattact attggggttg gtcaccagct
    37621 gccaatgcgt ggatgatgca aaccgtttat gaaacctatt cattttatag ggaccaagac
    37681 tatctcaggg agaaaattta tcccatgttg agggaaacgg ttcgtttttg gaatgccttt
    37741 ttacataagg atcagcaggc gcagcgttgg gtgtcttctc cgtcttattc cccagaacat
    37801 gggccgattt cgattggcaa tacttatgac caatctctga tttggcagtt atttcatgat
    37861 tttattcagg ctgctcagga attgggactg gatgaggact tgttgactga tgttaaggag
    37921 aagtctgatt tactaaatcc tttgcaaatc actcaatctg gtcgaatcag ggagtggtat
    37981 gaggaggaag agcagtattt tcaaaatgag aaagtggagg cccagcatcg gcatgcttcc
    38041 catctagtgg gactctatcc tggcaatctc tttagctaca agggacaaga gtatattgaa
    38101 gcggcgcgtg ctagcctcaa tgatcgtgga aatggcggca caggctggtc caaggctaat
    38161 aagatcaatc tctgggcgcg tttgggagat ggcaatcgag cccataaatt attggcagag
    38221 cagttaaaga catccacctt gccaaacctt tggtgtagcc atcctccttt tcagatagat
    38281 ggtaattttg gtgctactag tggcatggca gaaatgttac tccagtctca tgcagcttat
    38341 ctggtacctc tagctgccct acctgatgct tggtcaacag gttctgtttc aggcttaatg
    38401 gcacgtggac attttgaagt gagcatgagc tgggaagata aaaaactctt acagttgacc
    38461 attttatcaa ggagtggagg agatttgcga gtttcttatc cagatattga gaagagtgtg
    38521 attaaaatga atcaagaaaa aataaaagcg aaatgcatgg ggaaagattg tatttcggtg
    38581 gcaacagcag aaggtgatct tgttcaattt tatttttaat aaggatttaa gaatataagc
    38641 agttttcaac tagttgaaaa agcgttataa tgataatagg aagtaatact caatgaaaat
    38701 caaagagcac aaactaggaa gctagccgca ggttgctcaa aacagtgttt tgaggttgca
    38761 gatggaagct gacgtggttt gaagagagat tttcgaggag tataatttgt ttgatagagg
    38821 gtgggtctga tggcttatat tgagatgaaa cactgttaca agcgttatca ggttggggac
    38881 acggagattg tggccaatcg tgatgtgaat tttgagattg aaaaggggga gctggttatt
    38941 atccttggag cttcaggtgc aggcaagtca acagttctta accttcttgg gggaatggat
    39001 accaatgatg aaggggaaat ctggattgat ggtgttaata ttgcggatta tagttcccac
    39061 cagcgcacca attaccgtag aaatgatgtg gggtttgttt ttcagtttta taatctagtt
    39121 tctaatctga cagctaagga aaatgtggaa ctggcttctg aaattgtgac agatgccttg
    39181 aatcctgatc aggtcttgac agatgtaggt ctggctcatc gtctcaataa ctttccagcc
    39241 cagctttctg gaggggagca acagcgagtc tccattgcac gcgcggtagc caaaaatcct
    39301 aaaattctcc tttgtgatga accgactgga gccttggatt atcagacggg caagcaggtt
    39361 ttgaaaattc tccaagacat gtctcgtcaa aagggagcga cggtgatcat cgtgactcat
    39421 aatggagctt tggcgcccat tgctgatcgc gtgattcaaa tgcacgatgc cagtgtcaag
    39481 gatgtggtgc tcaaccagca tcctcaggat attgacagtt tggagtacta gcatgatcaa
    39541 gcgaaaaact tattggaagg acttaattca gtccttcaca ggctccaagg ggcgtttttt
    39601 atccatcttg atcctgatga tgttgggatc tctagcctta gtaggcctca aagtaaccag
    39661 tcccaacatg gaggcgacag ctaatgctta tttaacaact gctcaaacct tggatttggc
    39721 agtcatgtct aactatggct tggatcaagc agaccaagaa gaactaaaac agacggaggg
    39781 cgcagaggtc gagtttggct atttgacaga tgtgactatg gataatgggc aggatgccat
    39841 tcggctgtac tccaaaccag agcgaatttc aacctttcag ctaagaaagg gacgacttcc
    39901 tcagtcagac aaggaaatcg ctttggccac tcatttgcaa ggccaataca gcgtgggaca
    39961 ggagattagt tttaaagaaa aagaagagga tcattcctct ttaaaagacc atacttatac
    40021 cattactggt tttgtggatt cggctgaaat cctctcccag cgagatatgg gctacgcagg
    40081 aagtggaagt gggactctga cagcctatgg ggtgatttta cctagtcagt ttgatcagaa
    40141 agtctacaat atagctcgtt tgaaatatca agatttagca ggtttaaatg ccttttcatc
    40201 agcttatgaa gaaaaatcca agcaacatca ggaagacctt gaacaaactt tatcagataa
    40261 tggcaaggta cgtctgcaac ttttgaaaaa agaaggacaa gagtctctag acaaggggca
    40321 agagaccctt gacaaggctc agactaattt gcaggaaggc aagcgtcgtt tagcagctgc
    40381 tcaagctcgt atacaggctc aagaaagtca actagccttg tttcctcaag ttcagagaga
    40441 gcaggctagt gctcaactta cccaagccaa gcaggaattg ggcaaggaag aggacaaact
    40501 aaagcaagct gaacaaaatc tagcccaaga aaaggaaaaa ttagaaaaac atcagcaagt
    40561 cttggacgat ttggcggagc caaggtatca ggtctataat cgtcagacca tgccaggtgg
    40621 tcagggctat cttatgtata gcaatgcttc atccagtatt cgagcagtgg gcaatatctt
    40681 tcctgtggta ctttatgccg tagcatccat agtgaccttt acgaccatga ctcgctttgt
    40741 agacgaagag cgaactcatg cagggatttt taaggccttg ggttaccgta gtaaggatat
    40801 tatcaccaag tttctccttt atggactagt agctgggact gtcggaacgg ctctaggtag
    40861 tatacttggt cattatttgc tagccagtgt aatttcaagt gtcattacaa aaggcatggt
    40921 ggtgggagaa acccagattc agttctattg gacctatagc ttactagctc ttgtcttgag
    40981 ttggttggcg agtgtgttac cagcctatct ggtggcttgg agggaacttc atgccgaagc
    41041 agcccagctt ctacttccta aacctcctgt caaaggagct aaaatcttat tggagcgtat
    41101 cggttttatc tggcgtcgtc tcagttttac tcataaggta acagcccgca acatctttcg
    41161 ttataagcag agaatgttga tgacaatctt tggtgtggca ggttctgtag ctctgctctt
    41221 tgcaggtttg ggaatccaat cttctgtagc aggagttccg tctaaacagt ttcaacaaat
    41281 ccaacagtat cagatgcttg tctctgaaaa tcctagtgcg accgatcagg acaaggtaga
    41341 gctagcagaa gtgttgaaag ggcaggagat actagcctac cagaaaatct attctaaaac
    41401 gctagacaag gatttcaaag gcaaggctgg tcttcaaaac attactctta tgatgataga
    41461 gaaggaagat ttgactccct ttatccatct tcaacatcat cagcaggagc tgacattaaa
    41521 agatggcatc gttattacag ctaaactcgc ccagctggca ggtgtcaagg ttgggcagac
    41581 tttagaaatt gaaggtaagg aactaaaggt cgctgctatt actgagaact acgttggtca
    41641 ctttatttat atgagtcagg ctagctatga gcaactttac ggacagctac cccaagccaa
    41701 cacttatctg gtctcattaa gggataccag tgcaactagt atcgaaagtc aggcgggctt
    41761 gcttatgaat caatctgcgg tgtccagcgt tgtccaaaat gtttcagcca ttcgactctt
    41821 cgactctatc gctagctcac tcaatcagac catgaccatc ttggtcatcg tatcggttct
    41881 attagctatt gtcatccttt acaatttgac caatatcaac gtagctgaga gaatccgtga
    41941 actctccact atcaaggttc tcggttttca taataatgaa gtcacactct acatttaccg
    42001 tgagacgatt gtgctgtccc ttgtgggaat cgtacttggt ctggtagctg gtttctattt
    42061 acaccaattt ttgattcaaa tgatttcgcc ttcgactatt ctcttttatc cgcaggtagg
    42121 ctgggaagtc tatgtaatcc cagtggtagc agtaagcatc attttgacct tgcttggttt
    42181 cttcgtcaat tattatctga gaaaggttga tatgttagaa gccctgaaat ctgtagagta
    42241 aggtagttat ttttagctga ttgaacttct atttactaat attcaaaaat cctccgtttc
    42301 aaagagcagg gaactctttg tgacagagga ttttttctat agggctttag cagctgcaat
    42361 tgcggcttcg aagtttggct cagaattgat attatccacg tattcaacgt agcgaatcgt
    42421 attgtcagta tcgaggacaa agactgcgcg tgctaatagg tgccattcgt tgatcaagag
    42481 ggcataatcg tgcccgaaag aatggtcaaa gtagtctgaa agcataatgg cattgtcaag
    42541 gccttcagca ccgcaccaac gtttttgagc aaaaggtagg tccattgaaa cagtcaatac
    42601 gaccgtgttg tccagtccag ccaattcttc attaaaacga cgtgtttgag ttgagcagat
    42661 gcctgtatcg atagaaggaa cgacactcaa gacttttttc ttgccatcaa aatcagccag
    42721 agatttttta gaaagatctg ttgtagtaag agaaaaatca agcgccttgt cgccgacttg
    42781 tagttgttta cctgtaaagc tcacaggatt tccgagaaaa gttaccatag gatactccaa
    42841 tcttttttct tccattgtat ctgaaacagt cagaattttc caatgatttg accggaaatg
    42901 tgggcataga aaaaacgcca gctcacatga gaatgacgtt tttcaaaggc ttattttgcc
    42961 aatccttcag caatcttgtc aaggttgtat ttcatcatgc tgtagtagct gtcgccttct
    43021 ttaccttgtt ctgcgataga gtcagtaaag atttgtgcgt agattgggat gtttgtgtct
    43081 tgagaaacgg ttttcattgg acggtcatcc acacttgatt ctacaaagag tgatggaact
    43141 tttgtttggc gaagtttttc aaccaaggtc ttgatttgtt caggagttcc ttcttcttca
    43201 gtattgattt cccagatgta ggcacttgga acaccatagg ctttagagaa gtatttgaat
    43261 gctccttcgc tggttacaat gagtttcttt tcagcaggga tcttattaaa tttatcctta
    43321 ctttctttat caagtttgtc taacttatca gtatattctt tgagattttt ttcatagaat
    43381 tctttattgt tagggtcttt ggcgctcaat tgtttggcga tatttttagc aaaaataata
    43441 ccgttttcaa ggttaagcca agcgtgtggg tcttcttttc ctttttcatt ttgaccttca
    43501 aggtagataa catcaacgcc gtcgctgact gcgaagtagt ctttgttttc agttttcttg
    43561 gcattttcta ccaattttgt aaaccaagca ttgccacctg tttcaaggtt gataccgtta
    43621 tagaaaatca aatcagcctc agaagttttc ttaacgtctt caggaagtgg ttcgtattcg
    43681 tgtgggtctt gcccaatcgg aacgatacta tgaaggtcaa ttttgtcacc agcaatattt
    43741 ttagtaatat cagcgatgat tgagtttgta gcaacaactt ttagtttttg accagaagtt
    43801 gtatcttttt ttccgctagc acatgctaca agaatgattg cagaaagaaa gagaacgagt
    43861 aatgtaccta attttttcat tagatcctcc aatttattag ggctttgccc cttattttaa
    43921 caaatgttta tttttcagtt tcaaatatcg ttgtttggga gcgataaaga agctaatgag
    43981 aaagaaacta gcagctgtaa gcacgatact agaacctgcc gcaacattaa aactatagcc
    44041 aataaagagt cccaaaactg aagcagtagc tccgaaggtt gaggaaagga aaatcatact
    44101 tttcagacta ttagcataca gataagcagt tgcagctggg gtaatcagca tggctacaat
    44161 caggatagtt ccgacacttt gcatggctgt cacagacacg agagtcagga gtaccatgag
    44221 aaggtagtga tagaaattga caggcattcc catggcttta gccaagagtt catcaaagga
    44281 agttatcaag agttgcttga agaaaatcca gattaacaag aggatggctg cccccacacc
    44341 catagtaata aacatatccg tatcttggac ggccagaata ttaccaaaaa ggatatggaa
    44401 aaggtcagtt gaacttttag cgacaccaat caagatgata ccgagggcta agaaagaaga
    44461 aaaggtaatg ccgatggcgg tatcgctttt gataatcgag tttcctttga tgtaggtaat
    44521 gatgatggca gctagcaatc caaagacaat ggctccgata aagaagtcaa ggcccaagat
    44581 gaaggagagg gctacacctg gtaagacagc atgtgaaatg gcatctccca tgagtgacat
    44641 cccgcgtaga ataatgaaac atcccacagc tccagctaca atcccgacga caatagctgt
    44701 tatcaaggca ttttgtagga aatggaattt ttgcaatcca tcgataaatt ctgcaatcat
    44761 aggtcacctc cattgaaaaa gagttgatta ccgtaagctt cttttagatt ggtttcggta
    44821 aaagtttctt ttgttggacc aaaggcaatc acttctcgat tgacaagtaa gacttgatcg
    44881 aagtagtggg gaatcttgct gaggtcgtgg tgaacgatga gaaccgtctt cccagctttt
    44941 ttcaaatctc tcagcgtatt catgatgatt tcctcactga cagagtcaat cccagcaaag
    45001 ggttcatcca agaggatata gtcggcttcc tgcaccaaac atctggcaat caagacccgc
    45061 tggaattgac ctccagacag ttgactaatt tgacgttcag cgtagtcagc taggccgacg
    45121 atttcaaggg cctcttgcac tttcttccaa tgtttagcct ttaaacttcg aaagagagga
    45181 atagagggaa atagtcctaa cgagacgcat tccttgacct tgatgggaaa gttgtagtcg
    45241 atattgattt tttgttcgac ataggcaatt cggtgtaagg attttttaac ttccttgtca
    45301 tcgagaaatg cctgaccttg atgtgggata attcccaaca taccttttaa tagtgttgat
    45361 ttcccagcgc cgtttggacc aatgatgccg gtaattgttg gtccatggag cactagtgaa
    45421 atatccttaa gtgccaacgt ttctttgtag gagacactga ggttttcgat acgtatcata
    45481 aacttgtatt cctcctgtct cttaatatac attaaaaaaa aaatt
//
LOCUS       DAVLDI010000012        43024 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLDI010000012 DAVLDI010000000
VERSION     DAVLDI010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43024
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.012"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..3542)
                     /locus_tag="VXD01_000620"
     CDS             complement(<1..3542)
                     /locus_tag="VXD01_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0601055.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQVIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGIEAKIQAQIEAADAAFDAEFDKREKAITDAIELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQAEALSRTKNELAGASTLIAQE
                     AKRIGLDSVARLEAFKLQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQVEV
                     LSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELSSKIASVQV
                     GGRNYIRGTKRMMLARGLWASGTFRPSGAGTAKTIDVLDSPATGFDKAIRLTSSNARD
                     QIGIAQDGFYISQGTYTMSCWVKGRRGQKVKLQTYWQVNDNSGISPIFTLKDENWTKL
                     SFTSARNRAGVASIGYVYLVNAEVGEYLDVLAPQLEDGSLATSSKEAPEDIEGQISTV
                     ESNFKQRADSLEAGVSRLTEGLRTKVDISSLNVTAENIRQSVKSLETDTQNKLNQKLS
                     QAEFEVRAGSIRQEILNATKDKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQD
                     IPKTGIWTTSTYTATIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIP
                     GSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNES
                     KQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQISTVESNFKQRADSL
                     EAGVSRLTEGLRTKVDISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSI
                     RQEILNATKDKADKTLVVSEAGKLREEFSKMKVGG"
     gene            complement(3547..3897)
                     /locus_tag="VXD01_000621"
     CDS             complement(3547..3897)
                     /locus_tag="VXD01_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601056.1"
                     /translation="MAQLTINGVAVKPPKYFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSKFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     FKPWSGAKFNLVER"
     gene            complement(3906..7559)
                     /locus_tag="VXD01_000622"
     CDS             complement(3906..7559)
                     /locus_tag="VXD01_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601057.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIKSTEAFKRFSNGQSWDQLDFQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIKRIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERITRALVALFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVVPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPIVALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICQAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTSALANIGAWFTDMFQKAWTGLTNIFSKLGSWFGERWNDVTSALSKVASWFGD
                     IFGKAFDAVKNAFSSIGDFFKGVWDTVKSIFVNAGQMVGEAVGGAFKSAVNAVLGTIE
                     NVVNGFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEA
                     VVPLENTGFIQTLGRVVSSAVVNAMAGVSPQGGFSGDGDIVIQIAGHEFGRVAIQEIN
                     KEHERAGQTLLKI"
     gene            complement(7546..7896)
                     /locus_tag="VXD01_000623"
     CDS             complement(7546..7896)
                     /locus_tag="VXD01_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601058.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQRQALLLHKERMRDFAE
                     RHNRKRKEEINGNS"
     gene            complement(7935..8315)
                     /locus_tag="VXD01_000624"
     CDS             complement(7935..8315)
                     /locus_tag="VXD01_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601059.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVVK"
     gene            complement(8320..8733)
                     /locus_tag="VXD01_000625"
     CDS             complement(8320..8733)
                     /locus_tag="VXD01_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0601060.1"
                     /translation="MLANGITLSYGEAKGTYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKEKLYFEQAYPDGTKVTFEG
                     QVSVKLGGGGVNAVIDFTLKIALQSELEFADGVGG"
     gene            complement(8736..9104)
                     /locus_tag="VXD01_000626"
     CDS             complement(8736..9104)
                     /locus_tag="VXD01_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601061.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            complement(9101..9616)
                     /locus_tag="VXD01_000627"
     CDS             complement(9101..9616)
                     /locus_tag="VXD01_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV0601062.1"
                     /translation="MSELLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPKGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            complement(9591..9929)
                     /locus_tag="VXD01_000628"
     CDS             complement(9591..9929)
                     /locus_tag="VXD01_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601063.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHKVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            complement(9910..10221)
                     /locus_tag="VXD01_000629"
     CDS             complement(9910..10221)
                     /locus_tag="VXD01_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEV0601064.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGERSRTEGGIAVVYGEKGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            complement(10223..10411)
                     /locus_tag="VXD01_000630"
     CDS             complement(10223..10411)
                     /locus_tag="VXD01_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601065.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGGELEITEERYVELADNIASNGVA
                     ISDVLEKILPEPEFLEED"
     gene            complement(10401..10583)
                     /locus_tag="VXD01_000631"
     CDS             complement(10401..10583)
                     /locus_tag="VXD01_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HEV0601066.1"
                     /translation="MSLLLRRHYIQEEQVSQYSDLENKTLEELKNLAKEAGIAGAYKL
                     SKAEIVEVLEDLKSEV"
     gene            complement(10588..11433)
                     /locus_tag="VXD01_000632"
     CDS             complement(10588..11433)
                     /locus_tag="VXD01_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HEV0601067.1"
                     /translation="MTAGQTKLATMVNPEVMADMVAAKLPKLIKFTPLAYVETKLEGQ
                     PGSTLTVPAWEYAGDATEIEEGQAITPDQLTTKKTTMTIKKAGKGYEITDESLLSGLG
                     DPLGQATYQLGLAIANKIDNDLVAVAKTATQHITETPTTLEAIDKALDIFEDEEDAQY
                     VAIINPKDATKLKTDVAKEWTKGSELGADMVVSGTFGEVAGVQIVRSKKVDEGKGFIV
                     KVSPSQTQTDDANKYGAFVIMLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGEG"
     gene            complement(11440..12009)
                     /locus_tag="VXD01_000633"
     CDS             complement(11440..12009)
                     /locus_tag="VXD01_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEV0601068.1"
                     /translation="MNEETQTVETVEEQKVPAEPAQQPQDEKKYTDADVDAIIDKKFA
                     KWKSEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAKAMLSE
                     RDLPVELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPVDSDGI
                     TKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            complement(12212..12463)
                     /locus_tag="VXD01_000634"
     CDS             complement(12212..12463)
                     /locus_tag="VXD01_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601069.1"
                     /translation="MLEKAKQLASQEFSRLSGREIKAEDCFVVWFSKTLQNWKALVST
                     NAITSSEPCGDYAEITHNGDKNETYVDVYAKVSNRAIKD"
     gene            complement(12465..12710)
                     /locus_tag="VXD01_000635"
     CDS             complement(12465..12710)
                     /locus_tag="VXD01_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601070.1"
                     /translation="MKYRKKPVVVEAVQWNGNNHKEVIDFAENKIWFDALGNIWIATL
                     EGDMVAKKGDYIIKGVQGEYYPCKLDIFAETYEKTEE"
     gene            complement(12753..13166)
                     /locus_tag="VXD01_000636"
     CDS             complement(12753..13166)
                     /locus_tag="VXD01_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0601071.1"
                     /translation="MIDIALAIAKKAHAGQVDKAGVDYIQHPLYVASQVNTEQEKAVA
                     LLHDVIEDSDITAADLFASGLSNEVVTAVQILTKKKGQSYQEYLGKVKSNNLARVVKL
                     ADLKHNSDLSRLKSVTNTDYERVKKYKNAIHYLST"
     gene            complement(13163..13372)
                     /locus_tag="VXD01_000637"
     CDS             complement(13163..13372)
                     /locus_tag="VXD01_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601072.1"
                     /translation="MKDIKYYRTTTNNAQVLRLIDGVMQVFDIEKKWVNSMDWFNKIF
                     FNDFTDFEEISENDAFTYIDRMVAA"
     gene            complement(13374..15011)
                     /locus_tag="VXD01_000638"
     CDS             complement(13374..15011)
                     /locus_tag="VXD01_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEV0601073.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEI
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPENEIKHLQSFSWVGDGSTYSTDIWKNTGKLTSSIKDELLMSLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLSYEEADIEKYIFVAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKVEYVPADM
                     TYKEWYSKYVAKDGEKVYNQDTREAKAKFYSEQLLSKISGVEPKITSDMQRIAGENKL
                     AGLEFRKKTVESLSRKITTDSQAENISLSKATSKINDALRYTTIFDPDTFAKEYLKMK
                     QKLIAEGYKIVKVKNTWLVDGPYKGVNTVVEKDGINFEMQYHTQESFDLKNGSLHELY
                     EKYRDTNTSDLERMKLFKEMLDLSNGLEIPKNIERVK"
     gene            complement(14920..16389)
                     /locus_tag="VXD01_000639"
     CDS             complement(14920..16389)
                     /locus_tag="VXD01_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0601074.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHNTESSHLKKLKSYYM
                     GEHAILKHTRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMTELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRPVR"
     gene            complement(16401..17699)
                     /locus_tag="VXD01_000640"
     CDS             complement(16401..17699)
                     /locus_tag="VXD01_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV0601075.1"
                     /translation="MSQTYQIKQNDIVVDLPKTVGAGYGQFWHSRSLYRVVKGSRGSK
                     KSKTTALNYVVRLLKYSWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFNKDELLQDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAELRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            complement(17677..18117)
                     /locus_tag="VXD01_000641"
     CDS             complement(17677..18117)
                     /locus_tag="VXD01_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV0601076.1"
                     /translation="MSGLRIKQKRFADEYIISGNATEAYKKAGYRVSSDRVAGVEGHK
                     LLKNPKIKSYIDERLKQLDSEKIADQQEVLSYLTSVMRGETQEQTLISIGELGQTITD
                     IDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            complement(18406..18488)
                     /locus_tag="VXD01_000642"
     tRNA            complement(18406..18488)
                     /locus_tag="VXD01_000642"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18455..18457),aa:Tyr,seq:gta)
     gene            complement(18569..18973)
                     /locus_tag="VXD01_000643"
     CDS             complement(18569..18973)
                     /locus_tag="VXD01_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV0601077.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWTDVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            complement(19044..19415)
                     /locus_tag="VXD01_000644"
     CDS             complement(19044..19415)
                     /locus_tag="VXD01_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601078.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFKEVPIVEEVKVEFEVE
                     ASTGRIYPETIIHLDISGYGNRVHSVHRFPGVFLTVGESIQLKILFYKRLRNFTADRF
                     LTFRESDWKFFIRDLVNEFVR"
     gene            complement(19412..19624)
                     /locus_tag="VXD01_000645"
     CDS             complement(19412..19624)
                     /locus_tag="VXD01_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000160160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601079.1"
                     /translation="MTKFVKIQSCYRGHTEDELINIDDIGRICLGPNILFLRTPYNLG
                     EHHISITQNSVDKLLKVLDIIGEDGK"
     gene            complement(19625..20125)
                     /locus_tag="VXD01_000646"
     CDS             complement(19625..20125)
                     /locus_tag="VXD01_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0601080.1"
                     /translation="MNIKALIKKYEELWNEHSPFYEPVPYTSMVELFLKELKQLDEPQ
                     KVKIPQFVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLDGYE
                     VEEEKRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEEAKFGWVFDCEGI
                     DIEEVE"
     gene            complement(20127..20441)
                     /locus_tag="VXD01_000647"
     CDS             complement(20127..20441)
                     /locus_tag="VXD01_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601081.1"
                     /translation="MEELKKKVNAVYNWTVEDGKPQPPKQNLPQAVKDRADYFWEMAE
                     DGMTFMGAMECIFADEKPTDYDLGSTKDWLPKSKEFDDWVGYSPSMARVIIAVYLIYR
                     GN"
     gene            complement(20592..20930)
                     /locus_tag="VXD01_000648"
     CDS             complement(20592..20930)
                     /locus_tag="VXD01_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601082.1"
                     /translation="MSYDLEILAKIESGDYICIAEPRYSSPTYNFGKMFRVAMDWDFD
                     QGTIYNVADIFENIKRGITELERQPEKYVQYEPANKWGTINDALYVLRSLRDCILEQD
                     IDTKYLYVRW"
     gene            complement(20930..21082)
                     /locus_tag="VXD01_000649"
     CDS             complement(20930..21082)
                     /locus_tag="VXD01_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601083.1"
                     /translation="MSYTVTLYFDNMVDETHFFKKEGDAAKCKAQLESKYRGDRMYKV
                     KMEEME"
     gene            complement(21376..22719)
                     /locus_tag="VXD01_000650"
     CDS             complement(21376..22719)
                     /locus_tag="VXD01_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0601084.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSNQAMLDGMET
                     FFSERSYNPVIEYMERAAEKWDGRNRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFIIARTTNQTEYLKDKTGER
                     RFLPIMADSRQQKKHPMEIDPDTIEQIWGEAVTIYRAGANLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKNSEKTNR"
     gene            complement(22722..23543)
                     /locus_tag="VXD01_000651"
     CDS             complement(22722..23543)
                     /locus_tag="VXD01_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEV0601085.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLIDFADKPAMTPSEIE
                     NFWDGYPNANIALKTTNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKDLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPNPLPEKEMMRTIESMIKKDRR"
     gene            complement(23716..24219)
                     /locus_tag="VXD01_000652"
     CDS             complement(23716..24219)
                     /locus_tag="VXD01_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601086.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKDLNWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALQRKAVGSYYNLVISVTKGKDGREFRNYDLEEEAQPLTEADI
                     DEDDLPF"
     gene            complement(24239..25015)
                     /locus_tag="VXD01_000653"
     CDS             complement(24239..25015)
                     /locus_tag="VXD01_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0601087.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYVNH
                     VDDKAILKILATIRGAVEPAKTEKTKEAPKKEVASDDELF"
     gene            complement(25015..25332)
                     /locus_tag="VXD01_000654"
     CDS             complement(25015..25332)
                     /locus_tag="VXD01_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601088.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            complement(25351..26544)
                     /locus_tag="VXD01_000655"
     CDS             complement(25351..26544)
                     /locus_tag="VXD01_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HEV0601089.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            complement(26507..26992)
                     /locus_tag="VXD01_000656"
     CDS             complement(26507..26992)
                     /locus_tag="VXD01_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601090.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            complement(26992..27351)
                     /locus_tag="VXD01_000657"
     CDS             complement(26992..27351)
                     /locus_tag="VXD01_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601091.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            complement(27351..27833)
                     /locus_tag="VXD01_000658"
     CDS             complement(27351..27833)
                     /locus_tag="VXD01_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEV0601092.1"
                     /translation="MASLYELTGQFLTIYQMDIDDETKTDTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            complement(27826..28548)
                     /locus_tag="VXD01_000659"
     CDS             complement(27826..28548)
                     /locus_tag="VXD01_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV0601093.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTTYTKTQIGEVRRRLGLPVGKV
                     YQGKLLTKEQHDYLVSIQKNKISRDVANEMNLKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNGGQFKKGNRPPNYVPVGTINYTTDGYPKEKIGEPNQW
                     VLKHRKVWEEHHGPIPKGHSIVFLDGDKTNYDILNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            complement(28562..28792)
                     /locus_tag="VXD01_000660"
     CDS             complement(28562..28792)
                     /locus_tag="VXD01_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601094.1"
                     /translation="MVRNKLTDLTNTLFAQLETLDDRDLTADELKTELQRSKQMVAIS
                     SQILQAGQLALDAKKFKDKAGEDNAPIALLEG"
     gene            complement(28793..29134)
                     /locus_tag="VXD01_000661"
     CDS             complement(28793..29134)
                     /locus_tag="VXD01_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601095.1"
                     /translation="MTQAERIREYYREHPAASYDEVAEVVGTTNSNVRANLAKDIKAG
                     RCVRLEDKSYDYSPYYNHTQALTELVDWKNDIRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            complement(29146..29337)
                     /locus_tag="VXD01_000662"
     CDS             complement(29146..29337)
                     /locus_tag="VXD01_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601096.1"
                     /translation="MMEYIYLVIIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMN
                     LRNSDKQFTYDVEPPEGLK"
     gene            complement(29334..29528)
                     /locus_tag="VXD01_000663"
     CDS             complement(29334..29528)
                     /locus_tag="VXD01_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601097.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEK"
     gene            complement(29525..29797)
                     /locus_tag="VXD01_000664"
     CDS             complement(29525..29797)
                     /locus_tag="VXD01_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601098.1"
                     /translation="METVQIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            complement(30040..30576)
                     /locus_tag="VXD01_000665"
     CDS             complement(30040..30576)
                     /locus_tag="VXD01_000665"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601099.1"
                     /translation="MESVLESLKQEKDHLEKIIKVVTSGGKFLRLPYQKKSRSISENL
                     KLISQNLDRLSCLYNQRGERMTDRELFKLPEDYVESTGLDKITFEVPFELFTKILKGY
                     GHKLAWEDFRQIKIHPSTRTKKTVGQCQFLFSIWMNDHLKPAIKPSKELQKEPVRKTK
                     KQKRLHKLAQNLLHRMKG"
     gene            complement(30608..30823)
                     /locus_tag="VXD01_000666"
     CDS             complement(30608..30823)
                     /locus_tag="VXD01_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001198773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0601100.1"
                     /translation="MQWTLEAMRINKGLTQAELAEKFEVSSQTIARLEKDSSDIGYQL
                     LKKYMFFFNVKFDDIFLGKKYENFVND"
     gene            complement(30836..31021)
                     /locus_tag="VXD01_000667"
     CDS             complement(30836..31021)
                     /locus_tag="VXD01_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0601101.1"
                     /translation="MWEQLNRIMQERNLNGYQLSKMSGVNRSFFSDLKSGKVKYLSWT
                     NICKIADALEVSLDEFR"
     gene            31169..31360
                     /locus_tag="VXD01_000668"
     CDS             31169..31360
                     /locus_tag="VXD01_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601102.1"
                     /translation="MKSFKYFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
     gene            31577..32266
                     /locus_tag="VXD01_000669"
     CDS             31577..32266
                     /locus_tag="VXD01_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEV0601103.1"
                     /translation="MIFQVKVNSSVSRPVTVEDICPNCKKPTNPDLVNSSYFSLGENK
                     TSLVLTCRCLGCKHFWTEEFIATRFLINDYTEKYEIEHIKVIPNLPSDIPISDDVEIV
                     SPIGKQIYVQALKAEHEQLDHIAGIGYRKALEFFVKDFSIVTNPDDEDKIIKMSLKQV
                     IEKYIKDEDLKTFALASAYIGNDEGHYYRNNPDKGFTDLKNYLHGVIHYMEMKLNFLD
                     AQELVNRSKKS"
     gene            32528..33295
                     /locus_tag="VXD01_000670"
     CDS             32528..33295
                     /locus_tag="VXD01_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001023158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0601104.1"
                     /translation="MQIIAENITHFRKQRGITQKELAKEVGITASTMTDYMKLRSAPS
                     FGVIQKLADYFGVKKSDIDTTFKEESTNSLPDAPDSLTQQIMDKVVQLITPNKKIVLR
                     TSEELLESQKNEEETKVNEVSENIIRLDDYRQTTYRRVTGVVSAGSGSIQDDDLDMEV
                     SFYEDEIPDDYDAIAYVVGNSMEPKIKNGDYLFIKNTQQVDYNTIGIFQVDGANYVKK
                     LRQGYLESLNPDYEDIHLDESNDIRTIGKVVSVYREK"
     gene            33317..34387
                     /locus_tag="VXD01_000671"
     CDS             33317..34387
                     /locus_tag="VXD01_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601105.1"
                     /translation="MELKEIIENIKKEIPVLDSSTDYWLVRANSGEYYTDFNLNGYIG
                     IGWNEITLEDIRRADNNSNVLKEILKEKLTFQDDSEPSENKYGITAGQLLRFVNNIKR
                     NDIVVVPSEGSERFLVGKVTGPLYELNQSQLEEYKSEELTHNRSDFAKRWKVYWLGWF
                     NRSDADSALYKMIYSHATLSNINDYKPFINRALFPCYIEDEKLYISYHVTEEKDIQGV
                     YLGQFVYQYSLLTRLLFPETRVDSKINVQSEGIIELITHTVNYGLIISAILSGAIVLT
                     SGGKLKFMGLELEVPGLINTYQEYQKNKLERIKQAKELADELGVPISELGIRIPRKLT
                     TAIESQKNVKLASSNPPEKSGE"
     gene            34757..35884
                     /locus_tag="VXD01_000672"
     CDS             34757..35884
                     /locus_tag="VXD01_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0601106.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMKEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(35972..36883)
                     /gene="whiA"
                     /locus_tag="VXD01_000673"
     CDS             complement(35972..36883)
                     /gene="whiA"
                     /locus_tag="VXD01_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV0601107.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(36880..37857)
                     /locus_tag="VXD01_000674"
     CDS             complement(36880..37857)
                     /locus_tag="VXD01_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV0601108.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(37854..38744)
                     /gene="rapZ"
                     /locus_tag="VXD01_000675"
     CDS             complement(37854..38744)
                     /gene="rapZ"
                     /locus_tag="VXD01_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV0601109.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(38796..39176)
                     /locus_tag="VXD01_000676"
     CDS             complement(38796..39176)
                     /locus_tag="VXD01_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV0601110.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(39187..39774)
                     /locus_tag="VXD01_000677"
     CDS             complement(39187..39774)
                     /locus_tag="VXD01_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV0601111.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(39783..41015)
                     /gene="clpX"
                     /locus_tag="VXD01_000678"
     CDS             complement(39783..41015)
                     /gene="clpX"
                     /locus_tag="VXD01_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV0601112.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(41047..41217)
                     /locus_tag="VXD01_000679"
     CDS             complement(41047..41217)
                     /locus_tag="VXD01_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601113.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            complement(41217..41723)
                     /locus_tag="VXD01_000680"
     CDS             complement(41217..41723)
                     /locus_tag="VXD01_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV0601114.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLSAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(41853..42371)
                     /locus_tag="VXD01_000681"
     CDS             complement(41853..42371)
                     /locus_tag="VXD01_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV0601115.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
BASE COUNT        11905 a         9703 c         7565 g        13851 t
ORIGIN      
        1 cctcccacct tcatttttga aaattcttca cgcaatttcc cggcttcaga tacaactaaa
       61 gtcttatctg ctttatcctt ggttgcgttc aagatttcct gacggataga gccggctcgc
      121 acctcaaatt cagcctgact caacttctga tttagcttgt tctgcgtgtc tgtctcaaga
      181 ctcttcaccg attgccggat attttcagca gtcacattga gtgagctgat atccactttg
      241 gttctaagcc cttcagtcag acggcttaca ccagcttcga gtgaatcagc acgctgttta
      301 aagttggatt caactgttga aatctgacct tctatatctt caggagcttc tgaataagaa
      361 gtatctacat cgcttatttc aaacttcggc atccaaatcc aaacagttcc ttcctggttg
      421 aaattgaaca accattcatt tgtggtctgc ttggattcgt ttgtccaacc ttttggaata
      481 tggacaacat atcgtttaat ttctgtcgac aatgtcacat ttccagtttt atatccgata
      541 ttccctaatc gagatcttag cattattcca tttttatttg ccttagcata aaaactaatg
      601 gttacatctt gattagtcgt acttccggga attactttcc cgaattgacc cagagctgga
      661 taagtaacct tgggattccc tccatcacga ccagatggat tcagacctat aattttaaga
      721 gccttgtgtc caagatactt actttcgcta tcgatagtag ccgtatatgt actcgttgtc
      781 caaattcctg tttttggaat atcctgcttg aatagtgagt tcaagaatag atttcgaccg
      841 gatgcctgca cactcgcaat ccgactagcc agctcctcag ctgtctgcgt gagttctgac
      901 ttgctggctt tatccttggt tgcattcagg atttcctgac ggatagagcc agctcgcacc
      961 tcaaattcag cctgactcaa cttctgattt agtttgttct gcgtgtctgt ctcaagactc
     1021 ttcaccgatt gccggatatt ttcagcagtc acattgagtg agctgatatc cactttggtt
     1081 ctaagccctt cagtcagacg gcttacacca gcttcgagtg aatcagcacg ctgtttaaag
     1141 ttggattcaa ctgttgaaat ctgaccttct atatcttcag gagcttcttt tgagcttgtt
     1201 gccaaacttc cgtcttccag ctggggcgca agaacatcta aatattctcc gacttcagca
     1261 tttacgagat acacatagcc aattgatgcg actccagccc tatttctagc gctagtaaac
     1321 gatagctttg tccaattttc atcctttaat gtaaagatgg gcgaaatacc cgaattatca
     1381 ttgacttgcc aataagtttg tagcttgacc ttttgacctc ttctgccttt gacccaacaa
     1441 gacatcgtgt atgtgccttg cgagatataa aatccatctt gagcaatacc tatttggtct
     1501 ctagcattgc ttgaggtcaa tcgtatcgct ttatcaaagc cagttgctgg actgtctaat
     1561 acatcaatcg tctttgccgt cccagcgcct gacggtctaa aagtacctga tgcccacaat
     1621 cctctggcta acatcatgcg ctttgtaccc cggatataat tcctaccccc gacctgcaca
     1681 ctcgctatct tactagagag ctcctcagct gtctgcgtga gttctgactt gctggcttta
     1741 ccattggcca agttggtcag ttctgacagt ctacgagtcg tcgtctcctc atacgtcgct
     1801 tgcgctgact tcacgccagc cagttcattc ttagtccgac taagtacttc aacttgcttg
     1861 gcaatctcag cttcagcctg tgcttgcttc ggtcgaatat cgtttgcgat agttcgtttc
     1921 agggcatcca agtcacctga caaagccgtc tgagcgctcg tagtctgcaa cttaaacgct
     1981 tcaagtctag caacagaatc cagtccaatc cgcttagctt cctgtgcaat tagggtactt
     2041 gcgccagcca gttcattttt agtccggcta agtgcttcag cttgcttggc aatctcagct
     2101 tcagcctgtg cttgcttcgg tcgaatatca ttcgcgatag tccgtttcag agcgtccaag
     2161 tcacccgaca gagccgtttg tgcgctcgta gtctgcgact taaacgcttc aagtctagcg
     2221 acagaatcca gcccaatccg cttagcttcc tgtgcaagca gggtacttgc gccagcattt
     2281 cgcaaagctt cctcagcctt gcgcttagtt tctttcaatg gcccgttgtc aaagctatta
     2341 aagcgctgat tgatagtgtc agacagttct ctcttgactt cttcagctct ggctttggca
     2401 agttcgatgg catccgtgat agctttctca cgtttgtcaa attcagcgtc aaaggctgcg
     2461 tctgctgctt ctatctgcgc ttggattttg gcttcaatgc catcttgttg cttaatctgc
     2521 ttggtaatcg taccctcgta agaatactgc gtatcatttc cagctttact atctgcgctg
     2581 atacgacctc ttagaccacc tttgaaagta aagctctgac ttaagacagg aactttaaag
     2641 gtttctttct tgttggtctg aatggttacc cactgcccaa cctcaagcag taaatgccct
     2701 tggtagttga gattatacgg atagtaagtt aggtttttca gtttgtaata caggtcattt
     2761 aaagcgctct gggtcatgaa gacattgtcc agttccaaag accggcctgt cttcataccg
     2821 accgtcagag acttcttgtc cgtcttacaa gtgataccag ctatctgata ctcaatctca
     2881 ctcttggtca agccatgcaa gaaataactg tcagcgttga tcgtgatatt ggactcagtc
     2941 aaatcacgga tttccatctt gccttctctg ttgaagaaac aagacatccc aatcacctga
     3001 gtcatagcgc tcagcatatc cctaaaggaa agtttcttac cctcaggaac ttgctcaata
     3061 tgataacgca tcgcgctgat tccgaaatag tcattcgcta actcaatgcc tgttttcagg
     3121 cagatttcct gaataacctc tcgtacttca gctgggaaat gcaaatccgt cacgtactca
     3181 cgattgagct taaacatacc gtccataagt tcaagtgtgg ttgtgttgcg gtttcggtca
     3241 atctcaatat cgttgatgaa gtattccccc atcttgaccc actggtaggt atccccaacc
     3301 agtagaccaa tctcagggtg cagggtatcc agcttattga acgtggtaat gatactggta
     3361 aaggtaattt taccgctacc agcgcaggtt ccaccaggct tataagtatc gcccttgatg
     3421 tagccatact caaaactagc ctctttgata tcccgtgaag catattcacc aacacgaata
     3481 gccagcgtcc tttccttggc aaacatggct ctgtcaaatt gtcgtctagt taaagcgtcc
     3541 attttcttac ctctctacca gattaaattt agcgccagac caaggtttaa acttctcagt
     3601 aaaggtatag ctaggagctg tcctatcacc gacatagaaa gtctttgtga cttggccatc
     3661 catggggtct ggataagata cctcaaaaaa tttagatgat acagcatgta aaagctgact
     3721 tatttctccc tgagtcatca taccccattc acagtctagt ttgcgtttgg tcgtgatacg
     3781 gtcacgcacc atgtcgccat tggcattacg ccctgtctct ccatcgatat cttgaatacc
     3841 gacttgaaaa tatttgggag gcttcacagc caccccattg attgtcaatt gtgccattta
     3901 acctcctaaa tcttgagcaa ggtttgacct gctcgttcat gctccttgtt gatttcttgg
     3961 atggctaccc gtccgaactc atggcctgcg atttggataa cgatgtcgcc gtcgccagag
     4021 aatccacctt gtggactaac accagccatg gcatttacta ccgcactgct gactactcgt
     4081 ccaagtgttt ggataaatcc tgtattttca agtggtacga ccgcctcttt accagcttca
     4141 ccaatcatgg cgattgttgg actatcgacg ataccaccac gggcaagacg agggaggcta
     4201 actgtactta cactaccaac ccatcctaga ccaggtaagt ttctgacaac gcctaaaact
     4261 ccattaatca ttccgatgaa gccattgact acattttcaa tcgttccaag aaccgcattg
     4321 accgcactct taaacgctcc acctactgcc tcgccgacca tctgaccagc attaacgaag
     4381 atacttttga cagtatccca aacgccttta aagaagtctc cgatagagct aaaggcattt
     4441 ttaacagcgt caaaagcttt tccgaatata tcgccaaacc agcttgctac tttggaaagt
     4501 gcacttgtaa catcgttcca tctctcgcca aaccaagaac ctagtttgct aaagatgttt
     4561 gttaagccag tccatgcttt ttggaacatg tcagtaaacc atgccccgat attagccaac
     4621 gcactagtca catctgccca acgttgtccg aaccatgagc cgattggtgt gaagatatta
     4681 acgatagcgt cccatgcacc ttggaataca ccagagaacc actctccgat gccagagaat
     4741 atgtttacaa tggcgtccca tgcttgctgg aatttctcgc caaaccattg acctatcggc
     4801 tcaaagattt cttgtagttt cgtccataga ccgctgaaaa attcgccaat cgcttgacaa
     4861 ataccactga taaaatcaca tagtccttgc catgcagttt tagcaaactc aacaacagtg
     4921 tcccagtttt gatagagcaa aacaccaata gcaatcaaag ctgcgattgc tgcaataatc
     4981 catgttattg gacttgtcaa aactgctaac gctgcattaa aagcccatgt tgcagctgta
     5041 gcgactcctg ctgcaacaga atgtgcaaat tccgccgcgg ttgctaatcc cattttcgct
     5101 gcatgagcag tccatgctag agctgattta ccaagttcta aagcagtttt tcctagctgt
     5161 gcaattgttt tacctgaatt gaccacaaaa tcttttgcat ataaggtgtt caaatagatt
     5221 gtttcaccaa aactgaccaa cttatcaaat gtcaatgctt taatagcaag acctagattc
     5281 ttaatccctc caacaatcaa agagacctta ctacctaaca agctgaatgc tcctgcaagt
     5341 cctccagctt gttctgccca tgataagaaa ttaatcgttt gccaagttgt tatcaaagct
     5401 acgataggtt ctttgttttc tttacaccag tcagaaaaaa cggtgaaacc atctgccact
     5461 aacttaatag catccgccaa tagtcccaaa gtggctaaaa ggccacctcc taataaatct
     5521 gaaattcctt caatactaac accgaatact cctgataaaa actcagcaaa aggttgccag
     5581 gaattctccc agagaatctg aataatgtca attagcccat taaaagcatt agcaatagag
     5641 ttaatagcag ggactacatg ttcatcataa acacgactta agccatcgcc aaatttgtta
     5701 acagaccttt caatgctctc aaatacaggc gcaacagtat ctaataaact ttggaagact
     5761 gatgaaattt taggagcgct tgtcacaacg actttttcaa aacctttaaa caaacttcct
     5821 gctaatttac taccaacttc aacaatggta gatgtcaaac tcaacagagt tgacacaata
     5881 gcgctaccga tacgaaccgc accagttgag gtaatgacgt cgtagaaagc actagaaaag
     5941 tcctgagcta tgtttcctac tgcctcggaa aggttaccaa cattatcaaa caaagcgact
     6001 agcgccctgg taatgcgttc tttttgcctt ccaaggccat ttgcaatact ttcggcaagg
     6061 aaaacaccga tacctagccc gatagtggtt attgagcctg tcacttgccc taaagcataa
     6121 gcaattttct cagccattcg gttaaaggca ttcacaaccc ttgggtcagt ggcgatttct
     6181 cccattgtct tagctatttg gtctaaggca gtcttaatgc gttttatacc ttctggtcta
     6241 aatgctgcat caaaaccttt cttgaagagg tcaaacaacc ctttgagctt atctccaaga
     6301 ccatcaaaaa tgctcttgaa tttgttgtcc atgtcggtca actcgacttc tggcaagatg
     6361 tctttgaaag gtccgccacc gcctcccttt cctttaccac ctttgccacc gcctccagaa
     6421 ccgcctgcgt cgtcatcttt tggtttttgc aagatgttaa tctcatcaaa tcccaaaaga
     6481 cctagcaact ctttagcagc tttcttagcg tttttggcgg agtctccaag attgtcagca
     6541 agtcctcctg ctgaatctcc agcgtcgtct actgcgtcag caaggtctcc tgctccgcct
     6601 gcagcgtctt tcatggcgtt ccccatgtct ccaactgctc caccgacacc atctttaact
     6661 gtagctttct tgttgaacat caaagcgata aactcagcga gtttagcagt cacgttcttc
     6721 aagaccatcg caaaagagtt taagacgggc ataatggcat tgataatcgg taacatagag
     6781 ttaccaaggt tcaatgctgc gtccttcatt agcgacttaa acaggctgat acgaccattt
     6841 acagaattag acaaggtatc tccatacttg gctgtagctt gctccaggat agccataaga
     6901 cggatttgtt gctgggtttg aaagtcgagt tggtcccaac tttgaccatt tgagaaacgt
     6961 ttaaaagctt cagtggactt aatcatagcc acattgacgt tgattcctag gtcctcaatt
     7021 gcttcggtgt tccctagcaa acctgagcga atccgctcca taacgtctgt aatcgtgcgc
     7081 cctgagcctt cagcaaccac tgccgatgtc tgcaacatct tagcagtata agcacttagc
     7141 ttgttggtgt ccttaataaa tccagaaaat aggtttgagt agactgcacc gtagttagta
     7201 gcctcaccca cacccatatt catagcgttg gcgttatcgt taacccattt taagaaagat
     7261 tgcgaactct cgcccatctg tcgcttgatt tggttcatag acgctgacac ttcaagagct
     7321 gtctgcgttg aatacatccc aacatcaagt aatttcttac caaggattgc aaaaccagca
     7381 aacttagcca gcttaccaaa cgcactaccg attgagttcg actgttcacg aactttggca
     7441 gtggcatttt tcacttggtc agatgttcct ttgacctgat tctcgacttc tttcatcttc
     7501 ttcctgaaag gcgctatctc agcgtcaatc atgaccttca attcatcaag agttgccatt
     7561 tatttcctcc ttcctttttc gattgtgtct ctctgcaaaa tcacgcatcc gttccttatg
     7621 caacaaaagc gcttgtctct gtcgttcctg ttctactgct tgttgttctt ctacaaacaa
     7681 ctcaggcgca tattcccaga actcaaaggc cttggcatct ttggataaca ataaagaaac
     7741 gtggttggat atcatctgcg aaagtctgta tgagtcaata atcttttctt tacgctcttg
     7801 gattttgaca cggttgtagc tttctatcat ttccctgatt tcaagcaccg tcaaatccca
     7861 aaaatcaaga ggcttgcccc cgatgtccaa aaacatagga taaagcctct caataatctg
     7921 agttaccgtt aagattactt gactactgtc attttcttct tggaagtttt cttgtccttg
     7981 cttcctcgtg gagtaaaacc cgatacttca aagagtggca ttaaaacctc tgtcatgaat
     8041 gttgtttggt ctcccccatt gtccacgtat tcatcgtata ggtcgtagac atcttcaaag
     8101 gaatacccat gttcatactg ctgcaaggct ccatgaacta acaacaacat aactttcaaa
     8161 ggtggcaaag tgaactcttc gcctgcttca ggcatgaaaa tcttcagcaa gttcatgccg
     8221 attttttctt ccacagttgc agcttgatga gatgtcaaac gtagcttcaa ctctttttcg
     8281 tcagtaactt tccaagttgt gtattttaac gccatttaat taacctccaa caccatctgc
     8341 aaattccaac tctgactgta aagcaatttt aagggtgaaa tcgataacgg cattgacacc
     8401 gccaccgcca agttttacgg atacttgacc ttcaaatgtg accttagtac cgtctggata
     8461 agcttgttcg aagtagagtt tttccttgtc gtctgctgcc ttacgcaata cacgataagg
     8521 agcagttgcg cttgaattat tataagagaa cttgtactca agttctccta tgtccccaat
     8581 accaaactcg tacttcttca ctgtatcttc aagagtagta ttttctactt tttcgagttc
     8641 aataccaaac tctggcactt ctttcaatcc aacaagttta gtataagttc ctttagcttc
     8701 gccataagat agcgtaattc catttgctaa catgtttaat tctccattct aaattgaaaa
     8761 acaagctctg agtctaaatc aacgacacct tcaaaacgca tgaccttatg tctcaaatga
     8821 gacgggtctg gcacgtcttg gcagtcggtt cttcgcaaac ctaaagactc aaaaatctga
     8881 ttgattttaa cagctaactc actagtgctg gtatcatcaa agatatccac cttgtagcgg
     8941 atagaggatt tttgttcctg gtcatcaaac caatcacccg gcttgttttg ttcttctaaa
     9001 aaaataacga ctgggaaagt ctcccaatcg ctaggataag tatcagtcac attatctgcg
     9061 accttttgca attctttata aataacaggc ttgatattaa tcattttatt tgttctctta
     9121 tctttctacg gacataattc gaaatattct tagacacacg ctcttgattg tctctcaaag
     9181 ctggataaag ataaggctgg gcaggttgac catacatctt gtagaactcc ccaatctttt
     9241 gaaagtggta aggtcctaca ttgatttggt cttcatgcac ataccacgga ctagacttgt
     9301 aagttacgct gacctctgga gagataccag aatggctagc ttgtcctttt ggtcccgttc
     9361 caaactcaac gtaaggagcg tattttaggt tggtgtaaac ctcgcctata gccttatctc
     9421 cgtccatttt tgccctagtt ttgatactag ttataagctc tccatctctc gctggtgcga
     9481 gtcttcttgc atctgcttgg acaaccttta tagtagcatt gtgtaccgca cgtaagacga
     9541 tatcctcgcc agttttttta ctagccaatc gtctacattt agctataagc ctatctgccc
     9601 ctagtagctc tgacacgctc taactccaaa acttgatgat gtgtgtagac ctttttagaa
     9661 atgaccttat gagtcacttc tgtctggcta tcgatacaca caccatcttt cactttgata
     9721 gtagctgatt tgttggcatt ggcattcaaa atatcattga cacgctcacc atacaattca
     9781 gattgcaact tgctactagc tggccacaat tcaagacgga ctgtctcagc ttccttggca
     9841 tacccttctt ttgcgacacc ttcctctgtg acagtctttt caaaccgtcg catcggataa
     9901 ggtttcagtc tactctgctt caaaaacatg gcctgccacc cttgctaatc tgtgcatgcg
     9961 tatacgctgt aaaagacccg tagacaggcc tttttctccg tagactactg ctataccacc
    10021 ttcggttcta gaacgctctc cttccgctcc tgagcggttg tggagctcga tagcaacctc
    10081 aggtatcaaa agacttaaag caggtgtcaa agatgtgcga ttagtctctg acaagataag
    10141 atttgtagcc cttgtttgga gcaacatgag aagctgagta tcttcttcgc ctgttaattt
    10201 cttcagcaac tctatagaca tatcaatcct cttctaagaa ctcaggttca gggaggattt
    10261 tctcaagaac atctgagata gcgacaccgt tgctggcaat attgtcagcc agctcaacat
    10321 agcgctcctc agtaatctca agctcccctc ctgccagtcg tttcacattt gattcccaat
    10381 catagaaatc ttgtttaatt ttaaacttca ctttttaaat cctccagcac ctctacaatt
    10441 tcggcttttg ataacttata ggcgccagct atgccagctt ctttggctag attcttcaac
    10501 tcttctagag tcttattctc taaatcagaa tactggctaa cctgctcctc ttggatataa
    10561 tgacgtcgta gcaataagct catgccgtca cccctcaccg aattttacaa ctcgtgtagg
    10621 gtcgtaaagg taaacaccat agtgttcatc accagtgata accgttgtct ttttaaggat
    10681 gtcacggtct gtttcgatag ccacatcacg ttttagcatg ataacaaacg caccatattt
    10741 gttggcatcg tctgtctgag tttggctagg agagactttg acgataaatc ctttaccttc
    10801 atcaactttt ttagaacgga cgatttgcac accggcaact tcaccgaacg ttccggatac
    10861 aaccatatct gcaccaagct ctgaaccttt agtccattct tttgctacgt cagtttttag
    10921 cttagtagca tctttagggt tgatgatagc aacatactgt gcatcttctt cgtcctcaaa
    10981 gatatctaga gctttatcga ttgcctcaag agttgttgga gtttctgtaa tatgttgtgt
    11041 tgcagtttta gctaccgcta ccaaatcatt atcgatcttg ttggcaatag ctaaaccaag
    11101 ctggtaagtc gcttgaccta gtgggtcacc aagacctgac aaaagagact catcggtaat
    11161 ttcataacct ttacctgctt ttttgatggt catagtagtc tttttagtag tcaattggtc
    11221 tggcgtaatt gcttggcctt cttcaatttc agtagcgtct cctgcatact cccatgctgg
    11281 cactgttaaa gtgctacctg gttgaccttc aagctttgtc tctacatacg ctagcggtgt
    11341 aaatttaatc aatttaggta atttagcggc taccatatcc gccattactt ctggattaac
    11401 catagtggct aatttagttt gtcctgctgt cattttctat tatcctttca atttcttata
    11461 aagctctggg ttcttttgat agagctcatt tcgactctga taacccatac gagcaaattc
    11521 ttcttttgtg ataccgtcac tatcgactgg cgcttgtttc attggagctc cgccttttag
    11581 tttttcttga acgccttttt gcacggcttg ctcccatgat ttctgcaata cagcgacaga
    11641 ctgcgatacc gtctctgcgc ttgtcaaatc aactacattt actaactcaa caggtaagtc
    11701 acgttcactt agcattgctt tagcttctgc ggtcaattcc ttgcgagcaa tggccttttc
    11761 acggtcggct agttcttgct cacgctgatc caactgatat ttctgcttct catcagcgtt
    11821 catcttagca agcttcttcg cttcgttttc tttagcttct tgctctgatt tccacttggc
    11881 aaacttctta tcgatgatag cgtcgacgtc tgcgtccgtg tacttcttct cgtcttgcgg
    11941 ttgttgtgca ggttctgcag gtaccttttg ttcttcaacc gtttcgactg tttgtgtttc
    12001 ttcgttcatt gcgaacctcc tatttttaaa gtcgtccccg actgtaattt ccatagcttt
    12061 tagtgtcgtc aatgcttgga caatataaaa accgtacggg attccatacg gttagggcat
    12121 aggaaaaccg catcaaatat gacacggttt atagcaattt acagtaattt atagcagtct
    12181 attcctgcaa gtcaagatgt tggatcacct cctaatcttt aatggcacga tttgaaacct
    12241 tggcgtaaac atccacataa gtctcattct tatctccgtt atgcgtaatt tctgcataat
    12301 ctccacaagg ttcgcttgat gtaattgcgt tcgtactaac aagagctttc cagttttgca
    12361 gggtcttgct aaaccaaact acaaagcagt cttctgcttt gatttcacga cctgataagc
    12421 gtgaaaattc ttgcgatgcc aattgttttg ctttttctaa cattttattc ctccgttttt
    12481 tcatatgttt ctgcaaaaat atccagcttg catggataat attctccttg cacgcctttg
    12541 ataatataat cccctttttt agctaccata tcaccttcaa gtgtagcaat ccatatattc
    12601 ccaagtgcat caaaccaaat cttattttct gcaaagtcaa ttacctcttt atggttattg
    12661 ccgttccact gcacagcctc gaccactact ggttttttac ggtatttcat tcctcactcc
    12721 tttctgggta cgaaaaaagc acttagatct ctctaggtgc ttaagtagtg aattgcattt
    12781 ttatattttt taacacgctc gtagtctgta ttggtaacag atttcaaacg tgataaatct
    12841 gagttatgtt tcaaatctgc aagttttaca actcttgcta aattatttga ttttactttc
    12901 ccaagatatt cttgataact ttgacctttt ttctttgtca aaatttgtac cgctgtaaca
    12961 acttcatttg acaagccaga cgcgaataaa tcggcagcag ttatatcgct atcctcaatc
    13021 acatcatgta aaagagcgac agctttttct tgttcagtgt tgacttgact ggccacatag
    13081 agaggatgct gtatgtaatc aacacccgct ttatctacct gccctgcatg tgctttttta
    13141 gcgatagcca aggcaatatc aatcatgccg ctaccatcct gtcaatataa gtaaatgcat
    13201 cattttctga aatttcttca aaatccgtaa agtcattaaa aaagatttta ttaaaccaat
    13261 ccatgctatt aacccacttt ttttcaatgt caaaaacttg catgacacca tcaatcaaac
    13321 gaagtacttg agcattgttc gtcgttgtgc ggtagtattt aatatctttc atatcacttc
    13381 accctctcta tatttttagg aatctcaagc ccattgctta aatcaagcat ttccttaaat
    13441 aatttcatgc gttctagatc agatgtattc gtatcacgat acttctcata gagttcatgt
    13501 aatgaaccat tttttaagtc gaaactttcc tgagtatgat actgcatttc aaagttgata
    13561 ccatcttttt caacgactgt attcacacct ttgtatggtc catctactag ccaagtgttt
    13621 tttactttta caattttata accttctgcg ataagcttct gtttcatctt caaatactct
    13681 tttgcgaaag tatcgggatc gaaaatagtt gtataccgca aagcatcgtt aattttactt
    13741 gtagcctttg ataaacttat attttcagct tggctatctg ttgtaatttt acgtgataat
    13801 gactcaactg ttttcttcct aaattcaaga cctgccaatt tgttttctcc tgcgatacgt
    13861 tgcatatcac ttgtaatttt tggctcaact cctgaaattt tggacaatag ttgttcgcta
    13921 taaaatttcg ccttggcttc tcttgtatct tgattataca ccttttcccc gtctttcgca
    13981 acatacttgc tataccactc tttataagtc atatcggcag gcacgtactc aactttacct
    14041 gtctctggat tccttgctct gcgcttcaac ttgctgtagt ctgcgtcctc atcgtatccg
    14101 acagtagtag acctacacca agggtgcata ggcggacaat tgacaccagg gacagcctta
    14161 tccctatcat agacctgatt gtcatgctcc tgacaaatgc gtgatgtacg cttgtctaag
    14221 acggccacaa agatatactt ttctatgtct gcttcttcat agctgagtag ttccatttgg
    14281 ttatgaaaaa aggctgattc tgtccgaacc aaacgtcttg catcgttctg acctacattg
    14341 aacctctcag caattgcttg tgcagtttct cgtgtatctc ggcctgtcat gaggctcata
    14401 agtagttcat cttttatgct agaagtaagc ttccccgtat tcttccagat gtctgtagag
    14461 taggtacttc cgtcacctac ccaactgaaa gactgtagat gtttaatctc gttctcagga
    14521 agcccagaaa agccatatgc tagtcctgtc tgctgttgta ggtcaaaggt agccttgtag
    14581 taactatcct tcatcaggtc gctataaaag gcatctgatc ctgtcttttc tgaatgatag
    14641 atagattcac gcatacggtc taaatcatca ctcaaacgct ctaggcgctt catgcggaaa
    14701 gaataagctg ggctgtctaa gtcagctagt aatctttgga tgttcgggtc attcggtctc
    14761 gcttcaagta ctttacgaag ttcattcaga tttttcttgt ctttcatgtt cttcaagact
    14821 tgtctagctt ctacctgact tagaccataa tcacgttgga atttatcgaa aatcttattg
    14881 atttccttat ccaagtaagt cttagcttcc tgatagacct tatcgaactg gtctgcctgc
    14941 ttttcggcct tgtccatctg ctggtaaatc agattggctt tcctcttcgc ccaatactcc
    15001 tgattcttca tcctctacct cgtcttcggg tttcgtgttg tctttgttga acatcggcat
    15061 gtcttccatg ttcttctttt tctcttcttc caaggcttcc agctcagcgt cagggtcttc
    15121 cacaaacggc aagagagaaa taagctgtct attggtcact ttgccttcca aattgttcac
    15181 aatctgagag atttctaaca agttcttagg caaaccacga ctgaattgtg gaacgattga
    15241 atgagactct aaagcaatct gcttcatgcc taagtaatga gcaaaaatcg caatacgctg
    15301 acgcaatcct cgcttatagt tcgcttcctt ggtcttagta atcatctcaa ggcccatcag
    15361 cttaaattcc atggctacgc ctgatgtatt ccctgcgaaa ttctcatcag tcaaattagg
    15421 cacatggcta aatgtgtaga tgtcctcttt aagagctgta cgcaagattt cagtagcact
    15481 ttcgtccagc gtattcttca agaactcagc ccttgcacta tcgcccggca attccaaaag
    15541 accttcttca gaaagaatct tcattgctac cttagcgtct tctggagtgt ctgctaactg
    15601 cgtgccatac aagacaagta tagactctac agcctgttcc ttatcattga cacgattccc
    15661 catcaaggaa ttataagcgt ctatcaagct aatttgttgc tcgtagtcgc caatcgcaaa
    15721 gtgattattg cgatactcga taattgggat ttgaccaagg ttgtgaggtg ttgcctcctc
    15781 gctctgagtt gttcctgaat ctgtacttct cagcaccatg tgatagtgca gattttcggt
    15841 aaagacctca gcctggtgct tggtagtgtc tttcgtatcg tcttttactt catagtaata
    15901 gaccgcaaac aaaggcttcc gctcaatact atcatcgtag accatgaaag tattctccgg
    15961 atcaatacta gttgaatcca actcagtcat accctcttta gcatagatgt actcgtaagc
    16021 acgaccatag atagccatgt tcaaagcatt ctgagcatct acttggtcaa tctcagcacc
    16081 atcaaaggct gtaagtagtt catcaatatc accgtcagca gtattgttat acttgatagg
    16141 attgcccata aaatagcccg tagccgtgtc tgcgatatcc ttggcatgat tagctaccgt
    16201 cttgtaattg ggtgcgttca cgttgcgtct cgtgtgtttt aagatagcat gctcgcccat
    16261 gtagtagctt ttaagcttct tcaaatgtga actttcagtg ttatgtatcg ttatcaattt
    16321 gtaaatcagg tctttcttca aagaaccctc atcatatcca tcccgtggat aggttaaata
    16381 ttggtacatg tctttcctct ctatagacca taatcagaac gtctgcggac ggttgctttc
    16441 ccaccttcga tacattgaag gctgtaacgc aaagcgtcca tcaagtggtt gtttttatcc
    16501 tctggtttat tcaaccagtt gccttcttta tctcgctggt agcagtaact ataaaattca
    16561 tccatgatgt ttttacaatc tggatgcaca taaatagcgt atccttgcaa tttggataca
    16621 cctgccataa tactatcctt acctttccga ctctctttta ttctagatat gccatgttct
    16681 gacctgagct cttcaatcag tcgtaattca gcgctatcag caatgatttg tgagcgatga
    16741 taacctttgt cctttatcat cttcgcaact tctttggtta tcaatccgac tttatacgcc
    16801 tcatcaaaga cataaatctc tttcgtcgtg tcatttatca acgaacaaca caaagcagtt
    16861 ggatcatgag taaaaccaaa gtcaagaccg atacataact tattagctga atcttgtagt
    16921 aattcatctt tattgaaatc cttgacagtc acgttttcgt agattaaacc ttcagcaact
    16981 ccccattcgc catcacaaac gattctagca cgtctggggt tcgtatgata caaatcctca
    17041 tagcgtttga tatcgacttc atcaagccac tcattgcatt tgtaagtggt tgtagtagcg
    17101 aatgtgtcag cccgtctcgt ctcttcatcg aagaatacac gcttgagcca atgcctctca
    17161 ttccacgggt taaatgtgac tgtgatttgt ttaaagaaat caggtacatc taagctacca
    17221 cggatagact caacaaccgt gctgaacttg tcttcagtct caatttgata tgcttcctcg
    17281 aaccatgccc aacaaagact gccgacatcg accgtgatag atgtgatttt gagttcatca
    17341 tccaaaccac ggaataggat tttttgacca gtcgctttta tggttatttc aggcaaagac
    17401 tcattgaatt taaacaaatg agtcaccccc aacacattac acgcccattt aaaatccgta
    17461 taagttgatt gcttgttggt attcgaatac ctacgaataa caagcaagtt ggcccaggaa
    17521 tatttcaaaa gacggacaac atagtttaaa gcggttgtct tggacttctt cgaaccacgg
    17581 gaccctttga ctacacgata aagacttctt gagtgccaga actgtccgta cccagctcct
    17641 actgtcttag gtaagtcaac gacaatatcg ttttgcttaa tctggtatgt ctgactcatt
    17701 tgcaaacacc accgttccag aaacgtctgc ctctactttg tctgtccaaa gcctatgacg
    17761 ttttcctaat agttcggctg ccttgattct gtcttttgct ccaacatcaa tatccgtaat
    17821 cgtttgaccc aattctccga tgcttatcaa agtctgttct tgcgtctctc ctcgcattac
    17881 cgaggttaga taactaagga cttcttgctg gtctgcgatt ttttcagaat caagctgttt
    17941 caaccgttca tctatataac ttttaatctt aggattcttt agtaacttat gtccttcaac
    18001 gcctgccact ctatcactag aaacacgata acctgctttc ttataggctt ccgtcgcatt
    18061 acctgagatg atgtactcat ctgcaaatct cttttgtttt attctcaatc cactcaattt
    18121 tccatcacca cctttcaaac aatcaaaaaa gccacacgat gtgcgacctt cttgcaaggc
    18181 gactacaacc ttgcgtgcgt attaaatttt gacttctttt tttatttttt gtagtcttta
    18241 aaacctctga gggaatcaaa ccctctagct tataacttat ccggaatata attagctacg
    18301 caatcatgcg aggtccagtc gcttccgcaa ccatttttaa gttaatgagt gatatgtgaa
    18361 tccccaccca gaagatttaa ctcattctgg gacacaaaca ctcaaaggag aggggaggac
    18421 ttgaacctcc aaggccatta cagccccctg acattacagg taaccatcta ccaattctga
    18481 gacctctctt ttcaattctt gatactacca ttctaacaga tttttagaac cgtgctgttc
    18541 caaaaagtcc cataagctca ctatgaggtt agatgacttc ttccaaagct aagaccgcct
    18601 cattttttaa cctgtagtag gttgtacgac tcatattcaa atcataacaa acgctatcag
    18661 cggtgccttt gttgatgtaa gtcattctta atactgccct gtactttgga tttttaagcc
    18721 tattgatcat tctacctaat tcaagttttc tgttaatgac ctctttagta tcctgctcta
    18781 tagcctcttt catcactacc aactgagtat agacgtcatc aacttttcta gtctgtccgc
    18841 cttggacttt gacgtcagtc cacttggggc ttgagagtaa acctgcctca agctcattga
    18901 tttcatctat acggctttga atgtccatgt ccagatcctg tagctctttc aagagctctt
    18961 tagccttgtt cactctctat ctccttttgt ggtataataa tattattgag attatagctg
    19021 agacagagag tgtcttggct tttttatcgc acaaattcgt tgaccaggtc acggataaag
    19081 aacttccagt cggattctct aaacgtcaag aaacgatccg cagtaaaatt tctaagcctt
    19141 ttataaaaga gtatctttag ctggattgac tcgcctacag tcaggaagac accagggaaa
    19201 cgatgtaccg aatgcactct atttccatac ccagaaatat ctaaatgtat tatcgtttct
    19261 ggatatatgc gccctgtact agcttcaact tcgaactcaa ccttaacttc ttctacaatt
    19321 ggaacttctt taaaaattgg tcgtgcagaa aatattggcg acggtgtttc ttgctttttt
    19381 cttcttcctg aatatggata tttacaaggt ctcatttgcc gtcctcccca ataatatcca
    19441 atactttcaa aagtttatct actgaatttt gagtgataga aatatgatgt tctcctaaat
    19501 tgtaaggtgt tcttaaaaac aagatattag ggcctagaca gatgcgccca atatcatcta
    19561 tgttgataag ctcatcttca gtatgtcctc tataacaaga ttgtatttta acaaattttg
    19621 tcatttattc cacctcctct atatcaattc cttcacaatc aaacacccag ccgaactttg
    19681 cttcttctag ttctttttga gtacctttat aattcctagc tgttatatct tgactaaaat
    19741 aaagagtact ccctgattgc gatttgacca aaggctgcct attttttaaa gtcaccaaat
    19801 accgcttctc ttcctcgacc tcgtagccgt caagccaagc aagacagaat ttttcgatgt
    19861 tattttcgta aaaccaatca ggaactttct tatcataatg atcttcaatt actctcattg
    19921 caccgtaaac atgaaaattg tttttctttt taaattctat atattccgcc acaaactgcg
    19981 gaattttgac tttttggggt tcgtctagtt gtttcaactc tttcaaaaaa agttcaacca
    20041 ttgaagtata aggtacaggt tcataaaaag ggctgtgttc attccacaat tcttcatact
    20101 tcttaatcaa tgccttaata ttcatcttag tttcctctat aaatcaaata aactgcaata
    20161 attacccgag ccatgcttgg cgaatagcca acccaatcat caaactcctt agattttggc
    20221 aaccaatcct tagtagatcc caaatcatag tctgtaggct tttcatcagc gaagatgcat
    20281 tccatcgctc ccataaacgt cataccatct tctgccattt cccaaaaata gtccgcccgg
    20341 tctttcaccg cttgtggtaa attttgcttg ggaggttgcg gcttcccgtc ttctaccgtc
    20401 cagttgtata ctgcattaac ttttttcttt aactcttcca tcacttcaac tccttgtcct
    20461 taatttctcc agtaagtcta ttttctaaaa tgtgacttgt atagcaaata tcgtttttat
    20521 aagtatagtg atcaacggtt tcttcaaccc attgattttt agtgtacggg tatctgtttg
    20581 gtcgtttcaa tttaccacct cacatataaa tatttcgtat caatatcttg ttctaaaata
    20641 cagtccctta acgatctcaa aacatataac gcatcattga tcgttcccca tttatttgca
    20701 ggttcatatt gtacatattt ttcaggttgc ctttccaatt cagttatgcc acgtttaata
    20761 ttttcaaaaa tatcagcaac attgtaaatt gtgccttggt cgaaatccca atccatagcc
    20821 accctaaaca tttttccaaa attgtaggtc ggagaactat atctaggttc agcaatacaa
    20881 atataatctc cactctctat tttcgctaag atttccaaat cataactcat tactccatct
    20941 cctccatctt tactttatac attcgatcac ctcgatactt gctctcgagc tgagccttgc
    21001 attttgcagc atcaccctct ttcttaaaaa agtgggtttc gtctaccata ttgtcaaaat
    21061 atagtgttac tgtgtatgac atttttacct ctttttttca aactgctacc gtgctaccga
    21121 taaaatctaa aaaaataaaa agttttttca agaatcccta ttttataggc tttctttatt
    21181 attactatta ttttatatac tttttttaaa aatataggta gaagagtagc attatatata
    21241 aatattaaat aaaagtcagt aatatcaagg ggttagactg ctaccgatgt gctaccgatg
    21301 tctcatttta tcggtagaat gctaccgatc taccccctca actgctaccg atgactaccg
    21361 ataattttta aattgctacc gattagtttt ttccgaattc ttcactctta cgaacccttt
    21421 tgtactttta cctcctgccc ggaaaacact ttttttccaa tcaggatgat tatccatgat
    21481 catgttaatc ttcgttgaca acttcctgtc attcgaattt ctcataaata agttgtacat
    21541 catttcacga gttgagacct tatctagttt tttgcttcca ggatcaaagt cgctactatt
    21601 atcgaaatat ttacttgtgt attgatgttg ttgctgaata gaccagtttt gccaattttc
    21661 agggacgggc atatcaagat attcaagcac ttgtaattca acttcatcac gatacatgaa
    21721 ctgttcacgg tagatattca attcatcctc tgtattttca tcaaacatca aattagcacc
    21781 agcacgatag attgtaacgg cttcgcccca aatttgttcg attgtatcag gatcgatttc
    21841 cattggatgt ttcttttgct gcctgctatc tgccataatc gggagaaatc gacgttctcc
    21901 ggttttgtcc ttcaggtatt ctgtttggtt agtagttctg gctataatga agtttttggc
    21961 aaactcttct gtgcgtttca tgtagggctt acgataccgt aagctagttt ttgatataaa
    22021 ggctttcgtt tcagcaaagc tcatccgatt actggccacc atttcatcat cgttgacgat
    22081 tagactcttt aacataatgt cgtaattatc tttattagag aaatcagtca cggcatccgt
    22141 ataccattcg ccacccaatt tttgaaggag ggacgttttc ccaactcctt gtccaccaac
    22201 cagatccaga acatagtcaa acttaacgta tggatcataa actttagcaa ctgcaccaac
    22261 tagccacatt tgagcgattt tagaaactaa agggatatct tcagcgccga gatatacttg
    22321 aagcatgcgg tcaatccggt ttctgccgtc ccacttttca gctgctctct ccatatactc
    22381 aataactgga ttgtatgatc tttctgaaaa gaaagtctcc atgccatcaa gcatcgcttg
    22441 gtttgagaaa gcaacaccta acacactttc aaagtaaact tttacgactg aatcaaagtt
    22501 agaagggagc tcaccttttt taaaaagagt gttgccgatc ttgatatctt taaggagttc
    22561 atgctcttgg gaaaaatcgt tgtgctttag gtaaatactc aactgatcat cagctttgaa
    22621 agacatcaac acattacttg gactgttggc cttgatgtct cccttggcag tcgttatcat
    22681 cttaggttgt gagtcaatac ttactacatt accaatcaca atcacctcct atctttttta
    22741 atcatacttt caatagtacg catcatttcc ttttcaggca aagggtttgg actatttgca
    22801 tttgctaatc ttgcaagttg aacaactaca ccatcgtcga ccgcacgata taagagacca
    22861 cctacgaatt ttgctagttt gtcatttcgt ccaccttcat caccaaaacc aagggcgatg
    22921 gtttcaaaga gatctgtagt ctgtgttcgg tctctagtat gtgaacgtct aactaaatcc
    22981 ctaagaccgt ccttaccatc atacttatag ccgtgagttt cgccatactg tttttttata
    23041 gactggatta aatcttttga aggagtgacc atcgtgccac cttccttaga cttttccaga
    23101 tcccactcat actgcccttt atctgtggca gagggtgcga ctaacacata attattttcg
    23161 tgagccttaa tatcaacacc aggcaagaat ccaatcatct gagtgatcgg ctcatcttct
    23221 cgtttgaagt agaatagatg tttaccgcca ctagccgtct tagcttgcag tgtcggttcg
    23281 attaaattta gatgtttcca tttttttagc gattcaaaac cgttcgattt gccgtgtttg
    23341 tcaatatcaa tgacaaagaa gttggtagtc tttagggcaa tgtttgcatt agggtagccg
    23401 tcccaaaagt tttcaatctc agatggagtc atggctggct tatcagcaaa atcaatcaaa
    23461 ggcatcttgt ttttaggatt gattggaatg actgagaacc ctaacttttg atactgtaat
    23521 gcgtattctt tcatcgacgg catgattact tctcctcttt gtaaatataa acaagttctt
    23581 gggccatata atttgattga tattcatctt cagtcgtttt taaataaaat aacaacgatt
    23641 gataagcctc ttcaaatgta ttgaatggtc ctaatctttc atcagtttca tcaatgaccc
    23701 aaaacttgct attttttaga aagggaggtc atcttcatca atatcagctt cagtcagcgg
    23761 ttgtgcttct tcttcaaggt catagtttcg gaactcacgg ccatctttcc ccttagtcac
    23821 agagataaca aggttgtagt aagagccaac tgccttacgt tgtagagcct cttccaaggc
    23881 tttaccgtct tcttcatttc cttgcatact gtcgccagca aggaccaagg ctttgataaa
    23941 gaatttcatg gtgcgttcaa ctgcccagtt aaggtcctta ccgttccatt cagtcagtgt
    24001 gccaaatgtt gcaaattcag agcgtccact gtaatcaccg ccacggattt caaattgata
    24061 accaaggctt tcccagcctt tgtccgatac gttgaaggtt gctttcttca ggactactgg
    24121 ataagtacca gctgggattg gtgcaggacc gttggcgctg tctttgcgtg ggtcaaagcc
    24181 ctcttttttg attgattttg cgatatctag taagctcatg tgtattctcc tttatttctt
    24241 aaaatagttc atcatcagag gcaacttctt tcttaggcgc ctcttttgtc ttttcggttt
    24301 ttgcaggttc aacagcccca cggatagttg ctaagatttt caaaatagcc ttgtcatcaa
    24361 catggttcac atagtaggtc ttacgcttgc ggtcaacctc acggttgtag ttgttgccga
    24421 gtttttcagt gtggatcatc aaatcagagt ttccattgat aagattgaca tacttatctt
    24481 tcaagcttgg tttgtctttg gtggcattgc cattgtcatc atattcagat acctgacggc
    24541 tgatgtaaat aacattcatt ggcaatgctt tgaggtcaat gactaattct gtgatagctt
    24601 ggttaaagaa gtcgtatcct ttgccgtatg gaatttccga caaggatttc aagcgaggtt
    24661 taccaactgg ggttaattca tcacaaactg caatcttaat catttcaata acatcgtcaa
    24721 ttacatcaat aacgactgtt tcataagagt gcttctgtgt ctggagagca agcaagatat
    24781 ctccaagctg cttaattact gaattggtaa ttcgtccctt gtcatctttt tcattgatca
    24841 gctgaatgct tggaacagtg ttagcttctg cattcccgtc tgtgttcaaa acgattggat
    24901 ttgggaattc atttgcaaga taagactttc cgctcatggt ttcaccgtag atgaaaaaat
    24961 ttcgtggggt atctttagga acttgtggtt tatttgctgg aagtgtaaat gccattagag
    25021 aacccctcca ataatatcct taatcatgtc ctcaattgat gaacggtcac gcttgatagg
    25081 ttcaacttct gatccattcg gataggtcaa tttgtattcc gcttcaactg cgacaatttc
    25141 acagtcaaaa gctgcagcaa gagccttgta agtctttttg ttgtcttcgt attttttacg
    25201 aggaagcttc aaacaatatt ccaagctaca aaagtcagct gcaaatgcta aagaacttct
    25261 gtccttgtaa gaattaagaa attctccagt tttacggcta cgaaatacga tcatttcagt
    25321 tgttttattc attttgtttt cctctttttt ttaactttct ttataataaa attcaattac
    25381 atttacatca tgctgctgac gacttcctgt tatgcgccag agcaattgtc gataatcatc
    25441 atattctcca gaaccttctt ctactggatc caatacgaca atagtttggt atttgtgttg
    25501 caagccgtct actccgacac ctaacacttg actagtagca accacgaatt tcttataaag
    25561 tccttcttga atatcgcccg tccagattcc aatttcagga tggcgctcgc taatgacgtt
    25621 gacaatctgc ttagatttac tgacaatcaa catatcgtgt ggtgctcgtt cgattaaacc
    25681 gtcaagttgt aacatcaatg gcgtatccgc atttactggc tttaattttg gaaaatcgac
    25741 tgctacgcct gtttgattaa ggtagcgttc aaaggtcttt cttccaaacg attgcttggc
    25801 cattgcagtt ttgccgtcca ctgttacaag atttagtttt ctaaattctg caagtttttc
    25861 tggattgcca gaggcgactc tcttttggta aaacttaatc tcaaaaccgt tattctcaac
    25921 tgcattctca attccttcaa tctcttccca gcggaagaaa ttaggcaagc tcgagatata
    25981 actttcataa ttttgaaaat cttcccactt ctcttttgaa tagctaaatg gatcatagac
    26041 catttttcca tgagtctttt gccagtcaaa tttattattt ggggttgccc aaccaaatac
    26101 cgttttttca agcggataga aattttgtcc ttttttccga attggtgtcg ctgaaagacc
    26161 tatcgtgtat tttcgcttta ttttgcgata taaggccact tgtttgtcag aagacatatt
    26221 ctgccattcg tctactatca gcacatcaca atctaattta tgcccctttt tgacttgatt
    26281 ttgaagatat ctatctgtct gaatgataat ctcaacacct ttatcaaaat tcataaactt
    26341 gactgcatct atccaaccat tcagaatagc tagtcgattg tttgtgatga tgattttttt
    26401 agctttttta tgttttgcaa tagcaagtgc acagatagtt ttgcctctgc ccccaagagc
    26461 ctctaaaaag attccattag ataaatgttc acttctttta atcgcttcag cttgccactt
    26521 tcttagcgtt attgtgatac tcactcacca cctttccgat atcatgaacc acttcttcaa
    26581 tatcatttct cattgcccaa aataatccaa gtcttgctgc tgctcgaata tcttgatgat
    26641 gacttttttc aaatttccaa aggtctaaga ttttcaaaag atcgtttgga atatccgact
    26701 tgtaacctgc attgaattga agaatggcac ctggatagca aagttggata taggcgatgg
    26761 tttctgccac gctattatct ttcgacttgt cgttatccct cgccttaaat tcttcaacaa
    26821 taactacatc gaattcaaga tttgttccga tttcgtgaaa ccaatcagcg aaacctctca
    26881 taccataaga gacaacccag ctatcaacta atcttgcatt atccaacaag acaactcctg
    26941 ttgtgctggt ttcaatttta ttactgcttg gatcaatagc taaaattttc atcaaacacc
    27001 aactttctca gtcagcactc ctggataaag ggcagtgtta aaccaatttt gtttatttac
    27061 ctttgcaaag gcaaatagcg atttaacttc ttttgcttgc ttctcaaatt ttcgaatatc
    27121 ttcctccgat tcaaagatag gtttttcctt gtatttagca actgtgacca gcttgtattc
    27181 cggagtgaat actggctttt catttccttg atcaagattg gtttcgtcta cttttacaaa
    27241 acgaatcgca acatcaaata gaaaaccttc agtaacaagt acttcaatcg attctggtcc
    27301 aatcacaact gctagtgaat ctgttactcg tgttttattc atcaattcca ttacttaatc
    27361 accaactttt ctgtccggac aagttccgca cctttgactt tcttgccaga tttaagcaac
    27421 tctttgagtg tttttttgtc cggcgcaagc gtcacttttt ttgtaaaata ttttttcgga
    27481 aggtcgtctt cgttgacctt gactgattct ggattcttag caatttttat aatcagggca
    27541 ccactcttaa cttcggtttg ccccgtgaca ttcatagctg ccataatgtt atcctttaca
    27601 taatccagct ttttctgtgc cacctgtttc ttggctttga agctctcttc ctcagccttg
    27661 tacatggcca cgtcggcttc tagattcttg ataacatggg catatccttc tgctttctgt
    27721 tcgaattgtt cttgccaatc gatagcctca agtgtgtccg tttttgtttc gtcatcaata
    27781 tccatttgat aaattgtcag aaactgacct gtcagttcgt ataaactagc catttttttc
    27841 tacctctctg attttgtttg tgagttttgt tagtccaata cctgatttgg ttaaatcagc
    27901 gttggacgta aataaatgat tttgattcat tctagcaatt tcgtttttag ataaacatgc
    27961 caggtttaaa atatcatagt ttgttttatc accgtccaag aagacaatcg aatgcccttt
    28021 tggtattggc ccgtgatgtt cctcccaaac cttgcggtgt ttcaaaaccc attgattagg
    28081 ttctccaatc ttttcttttg gataaccgtc tgttgtgtag ttgatagtac cgacaggtac
    28141 ataattcgga ggtcgattac cttttttgaa ctgcccgccg ttttttggca tattggggta
    28201 cttcttcccc ttattgtgag gagtctgacc tttctcgaat cttcctgtca aaccactatg
    28261 tagattatta tttcttcgat aactcttaat ctgtttctca gtcagtgata atccaaattt
    28321 taggttcatt tcatttgcga catcgcgaga aatcttattt ttttggattg acacaaggta
    28381 atcatgttgt tcttttgtca acaatttacc ttgatatact tttccaacag gtaaccctaa
    28441 acgtctgcgt acttctccta tttgagtctt ggtataggtc gtaccaaatt tctcatttag
    28501 taacctggtt acttcaggag ttaatcggcc agggcatatc tcatgcatgt actctgtata
    28561 ctcatccttc cagcaaagcg atcggggcat tatcctcacc tgccttatct ttgaacttct
    28621 tagcatccag ggcgagctgt cctgcttgta agatttggct agagatagcg accatctgtt
    28681 ttgaacgttg gagttccgtc tttaattcat ctgcagtaag atccctatcg tccaatgttt
    28741 ccaactgggc gaaaagagta ttggttaaat ctgtcaattt atttcgaacc atctacttcg
    28801 tcacctcttt catcaattta tttgcttctt tgattaacaa acgcataaca ttgctatccg
    28861 tttctttttc tgctgctctt gtcagcatat ccacccactc acgtctaata tcattcttcc
    28921 aatcaaccaa ctcagtgagt gcctgtgtat ggttatagta aggcgagtag tcgtatgact
    28981 tatcttccaa gcgaacgcat ctacctgcct tgatgtcttt ggccaggttc gctctcacat
    29041 tactatttgt tgtaccaacg acctcagcca cttcatcata tgaggcagca gggtgctctc
    29101 tataatattc cctaattcgt tcagcttgag tcatgtttct cctccttatt tcaacccttc
    29161 aggcggttct acatcataag taaattgctt atctgaattt ctcagattca tccgtgcaac
    29221 attgtttgcc atcagctggc gctctttttg tttcatttca gcgtggtcat ctagtttatt
    29281 tactagcgac catagtccaa ttcctacgat tattaccagg taaatgtatt ccatcatttt
    29341 tctttctcct tttctttgta gattgctacg attttcttca agtctgcgat ttcttgattc
    29401 gcttcttgaa gtttttcctg tgtttcaatt agtgattgat tgaggtctaa agcgacctct
    29461 ttccagtcga gattagtttc tttgacctct tccgaaaaat agtttttgat tcttgatagt
    29521 aggttcatcc tgctgacctc attttcttgc ttgtttccat ttcttttttc caagctttag
    29581 ttccacgata ttgcaagtat tcatagaaac ctttaatcgt tacaagttgt ccactatcca
    29641 aaagatgttt ttgctgacta gggagttttt gcatttctct tcttcgctct cctgcttgtc
    29701 gttttgaaca tccaaagata cgttttaact cttcatcatt agcagagact ttttcaatga
    29761 tcacgtcttt aattctcacg atttgaactg tttccatttt tgctcctttc gtgttataat
    29821 ttagttagtt atttttgatg agcgcctgac ttcgttaggt gcttttttct gctactcaat
    29881 cttcttatcc tttcttctct cgttttctgc tataatacat acagaaagga ggataactta
    29941 tgactaagtc tgatttggga ccttatctag atgcagttac aaacgaagat ggtactcttc
    30001 taatctgcaa aacagagcaa ggtgcataca ttggcgattt caacccttca tgcgatgaag
    30061 aagattttgt gctaacttat gaagacgttt ctgtttcttt gtcttacgca caggttcttt
    30121 ctgcaactct tttgaaggtt taatcgctgg cttcaaatga tcattcatcc aaatactaaa
    30181 caaaaactga cactgtccaa ccgtcttttt tgttctagtg cttgggtgga tttttatttg
    30241 tcggaaatcc tcccacgcta acttatgtcc gtaccctttt agaattttcg taaacaattc
    30301 aaaaggtact tcaaatgtaa tcttgtcaag tccagtagat tctacataat cttctggtaa
    30361 cttaaatagt tctctgtctg tcattctttc tcctctttgg ttatataaac agctcagtct
    30421 atcaagattt tgagaaatca atttcagatt ctcactaatc gagcgtgact ttttttgata
    30481 cggcaatctc agaaatttac caccagaggt aactacctta atgatttttt cgaggtggtc
    30541 tttttcttgt ttcaagcttt caagaacgct ttccatctat gtgttcctcc ttcttatttt
    30601 tttgtttcta gtcatttacg aaattttcgt attttttacc taaaaaaata tcatcgaatt
    30661 tcacattgaa aaaaaacatg tattttttca atagctgata accgatatca gagctatctt
    30721 tttctaatct agcaattgtt tgacttgaaa cttcaaattt ttctgccaac tctgcttgag
    30781 taagtccttt gttgattctc atagcttcta aagtccactg cacgttccta cctccttatc
    30841 taaattcatc caagctgact tccaatgcat cagcgatttt gcatatatta gtccaagaaa
    30901 ggtactttac ctttccactt ttcaaatcag aaaagaaact acggttgact ccagacatct
    30961 tagataattg ataaccattc aaatttcttt cctgcattat tcggtttaat tgttcccaca
    31021 ttttacaccc ccaaaaacac tatatgttgt taaacaaata tatttaatta acaatatgtt
    31081 gtgtttttct gttatctatg ttataatcat tcttgactaa gacctctcac cgttttagtc
    31141 aaaattccaa tagaaaggag gagattttat gaaatccttt aaatattttc gagaatcttt
    31201 aacagctgaa gatatgcaag ctatctctgc taaagctaat gaagctacta aacagattga
    31261 ccatacagac ggattgcaac tggggaaggt cagtggtttg acttctgtaa taactactat
    31321 tgagttactt gagaagtatc atgaatggct tcatagctaa gacgcttaaa ttcttctaag
    31381 tctatctgaa aattgatagg ctttttttgt aaacactcaa gaaaactagt gtttcttaaa
    31441 agtttttcaa ctaactcagg gtcggccttt acaaaggtgg actctttttt cccactatac
    31501 ggatatcgtc ttggtctcat ttcctcaccc cctttcaaat atggtataat caaaataaaa
    31561 cgattggaga aatcttatga tatttcaagt gaaagtaaat tcttctgttt ctaggcctgt
    31621 aaccgttgaa gacatttgcc caaattgtaa aaaaccaacc aatccagatc ttgtgaactc
    31681 ttcttatttt tctcttggag aaaataaaac aagcttagta ttaacatgta gatgcttagg
    31741 ttgtaagcac ttttggacag aggagtttat agctacaaga tttttaatca atgactatac
    31801 cgaaaaatac gaaattgaac atatcaaagt aatccctaat cttccgagcg atatacctat
    31861 atctgacgat gtagagatag tttctccaat tggtaagcaa atctatgtcc aagcactgaa
    31921 agctgaacac gaacaactag accacattgc aggtattgga taccgtaagg cgcttgagtt
    31981 ctttgttaaa gatttctcca ttgttacaaa tcctgatgat gaagataaaa tcattaaaat
    32041 gtcattaaaa caagttattg aaaaatatat caaggatgaa gaccttaaaa catttgcgct
    32101 tgcatctgct tatatcggta acgatgaagg tcattactat agaaataatc ctgataaagg
    32161 ttttacagac ctaaagaact acctacacgg agttattcac tacatggaaa tgaaactcaa
    32221 tttccttgat gctcaagagc ttgtgaatcg ttcaaagaaa tcttagaatc tacttcatcc
    32281 aacttctcag ctatatatgt cacagtcctc aatatctcat tgagggctgt tctttctagt
    32341 tcgttcattt gtcttacctc cttttcctta agcttgattt aattataata cgattttttc
    32401 gtattgtcaa tagtttttat caaaaaaata ggattttttc gtatttttga ttgtttatca
    32461 ttcaaaaatg atatataatg taattataaa aaatacgagg taatcgtaaa tggacgaaaa
    32521 aaaacgaatg caaattattg ctgaaaatat tacacacttt agaaagcaac gtggcatcac
    32581 ccaaaaagag ttggctaaag aagttggaat tacagcaagt actatgacag actatatgaa
    32641 gttaagaagc gctccttctt ttggtgttat ccaaaaactg gctgattatt tcggtgttaa
    32701 aaaatcagat atagatacta cttttaaaga agaatccacc aactcactgc cagacgctcc
    32761 agattcgctc acacagcaga taatggataa ggtagtgcaa ttaatcactc caaacaaaaa
    32821 aatcgttctt cggacgtctg aagagcttct ggagagtcaa aaaaacgaag aagaaacgaa
    32881 ggtaaacgaa gtatcggaga acatcatcag actggacgac tacagacaga ctacttaccg
    32941 acgtgttact ggggttgtct ctgctggtag tggttcgata caggacgacg atttagatat
    33001 ggaggtttcg ttctatgagg atgaaatccc agacgactac gacgctatcg cttatgtcgt
    33061 cggcaactct atggagccaa agataaagaa tggcgactat ctttttataa agaataccca
    33121 acaggttgat tataacacta tcggcatctt ccaagtagac ggcgctaact atgttaagaa
    33181 actgcgtcag ggatatctgg aaagcttgaa tccagattat gaggatatac acctagacga
    33241 aagcaacgat atccgaacta ttgggaaagt cgtgagtgtg tatagagaga aataaaaaag
    33301 aaagtaggta attacaatgg aattaaaaga aattatagaa aatataaaaa aagaaatccc
    33361 tgttttggat tcttctaccg actattggct agtacgtgct aactctggag aatattacac
    33421 ggattttaat ctaaatggct atataggtat cggatggaat gaaatcaccc tcgaagatat
    33481 tagacgagca gataataact cgaatgtatt aaaagaaatt ttaaaagaga aattaacatt
    33541 tcaagatgac tcagaaccat ctgaaaacaa atatggtatc accgcaggtc aactccttcg
    33601 ttttgtaaat aacattaaaa gaaatgatat agttgttgtg ccatccgaag ggtctgaaag
    33661 atttttagtt ggtaaagtaa ccggaccgct ctatgaactt aatcaatctc aacttgagga
    33721 atataaaagc gaagagttga cacataatcg gtcagatttt gcaaaaaggt ggaaagtcta
    33781 ttggttggga tggttcaatc gttccgacgc agacagcgca ttgtataaaa tgatctattc
    33841 tcatgcaaca ctatcaaata taaatgatta taaaccgttc attaaccgcg cactttttcc
    33901 ttgctatatt gaagacgaaa agctatatat tagctaccat gtaacagaag aaaaagatat
    33961 tcaaggggta tatttaggtc aatttgttta tcaatattct ctattaacaa ggttgctttt
    34021 ccctgaaaca cgagtagatt caaaaataaa cgtacaatct gagggtataa tagaacttat
    34081 tacacacact gtaaattacg gacttataat ttcagcgata cttagtggag caattgttct
    34141 gacaagtggg ggaaaattaa agtttatggg attagaacta gaagttccag gattaataaa
    34201 tacatatcaa gagtatcaaa aaaataaact cgaacggatt aagcaagcaa aagaactagc
    34261 tgacgaactc ggtgtaccaa tatctgaact aggcattcgt attccaagaa aactaacaac
    34321 agctattgaa agccaaaaga atgtaaaact tgcttccagt aatccgccag agaaatctgg
    34381 agaataaaaa aagtctaaca tcagttagac tcgaagaaaa tgaatttctt tagttttaat
    34441 gagataagca tagctatcgc taaggaaaga taatcgtttg tgataaaaat tgtggttatt
    34501 gagaaaaata tcttgaaaat caagagaaat aaaaatatag atacaataaa attttttaac
    34561 tttgttttca acatattttt tctccttatt cttttgaaac aattataaca caattatctg
    34621 ttaaagttaa ataattctaa aaaatcccca cactctccat cgccaaactt tgagtgtgag
    34681 gatatcctgg atagtaaaag gcattaaaaa gccctcttta ctatacccat tttatcaaaa
    34741 agtgaggtta aaatcaatgt ggatggaaga attaccaaac ggcaaatata aattttttga
    34801 gcgatacaaa gatccatata ctgagaaatt aaaaaaagtt tcagtaacca tggagaagaa
    34861 aactccccag gcaagaaatc aagctgctat cttgttgcaa gagaagataa ataaaaaact
    34921 tagcacaaaa caagtagaaa gcattacatt tgaagaaatc tataaccttt tttataaatc
    34981 atgggcgcaa acagtaaagg aatcaacaaa acataattgt aaatcagttg ataagaagat
    35041 gaaggaagtc ataccatccg ataccatact tgctaatctt gacaggcgtt ttcttcaaga
    35101 ggctattgaa aaaattattg aaagcaacgg atatattaca gctaaaaaag tacggcatag
    35161 gctcagaggt atctttaatt acgctgttca atactcttac attgaaaaca acgaggtcga
    35221 ttatactacg attcctcaaa aaccaaagac tttagaagaa ctggaaaaaa agcgtaacaa
    35281 ctttctcacc atgaaagaaa taaaagcact tgtcgatgtc cttaatcgtc gagaatatca
    35341 ccaaaagtac gctgatatgg ttcttgtgct gacattaact ggtatgagat atggtgagtt
    35401 aactgcctta caactgaaga atatagactt cgaaaacaac aaaattgaga tcacaggtaa
    35461 ttttgattca gtaaacaaaa tcaagacgct accaaagact acaaattcaa tacggacaat
    35521 caaagtatca gagagtgtca tagaagctat tcaaagacaa atagtacgac ttagcgaacg
    35581 tttccagcca ttgtcaagcg atgattatat tttctgtttt gaaaaatgga atcaacctac
    35641 aacaatagct tgcttcatac agatattaaa aaaatatgga aaacaggcca aaatagaaaa
    35701 aaacttatct agccatattt ttaggcattc tcatatttcg tttttagcag agtctggcct
    35761 cccaataaaa tcaataatgg atcgagttgg gcactcaaat gcaaaaatga ctttggaaat
    35821 ctattctcat actactgagg atatggagga taaactggtc aataaattag atactatttt
    35881 ttaattctgc cccttggttg cccctttttg atttcataac acaacaaaac cccttgaaga
    35941 tattgataat tcaaggggtt gctttatatc gttataattc atccgctatc ttattgattt
    36001 ttctgagtct gtgattgaca ccacttttgg tcagaggggt gctgagacta tctgctaact
    36061 gctggataga gtagtctggg tgctgaatcc tcagttgcgc cacttcctgc aaatctactg
    36121 gcaaattttc taagcccatg atatctttga ttttactgat attgttaatg gtcttcatgc
    36181 tggcagaaac tgtccgagcg atattagctg tctcggcatt attagcccga ttgaggtcgt
    36241 tacgggtttc tcgcaaaatc ttaacccgct caaaatcatc acgtgcctgc atggctccga
    36301 ttactatcaa gaagtccata atgtcttctg ctcgctggag ataggtcaca gcccccttct
    36361 tgcgctcaag caccttggca tccagtaaaa actgttggag aagggaggca attccttgcg
    36421 cgtggtccag ataaacagaa ctgatttcca actggtactt gcctgactca gggtcacgaa
    36481 tgctcccatt tgccaagaaa gcgccacaga gataggcacg acctgcttcc tcatccgata
    36541 aaatcgcctc atcaatacct gtttccaggc caaagaaaga gtctgccaag tgcaaatcac
    36601 ttaacaaatc ctgcaccttt tcatctgtaa aaacggtata gacgcgattc ttgcgaagat
    36661 tgctccgttg gtggtgacga atttcagatt tgatttcata gaaatgaaga aaggactcat
    36721 agaggtgacg ggccagtttg gcattttctg tcacaactga caaagtcaag cccgaagtcg
    36781 agagaccgat gctaccagac attttgataa tggcagataa ttcatgccag ctcagatggt
    36841 gttggcccag gatttcttct tttactgcta ctgtgaaact cattttttca cctgtataat
    36901 gcgcatcaac tcgtccacaa tcaaatctcc atcgtggaag gcaccgccat tttccagacg
    36961 aaggaagtta gatgaaatca cgcgcgaaac ttgcttacaa agacctacaa aatcgtgttc
    37021 cacttgcact aagtattcat caaaacggtt ggaattcatg tattcctgag gcactttttc
    37081 aatattcacc aagacagtgt cgataaaagg gcgaccaagg tgacgatgca agacttccac
    37141 gtggtcgcta tctgtaaagt gttccgtctc cccacgttgg gtcatgatat tgcagacata
    37201 ggcaatttct gccttagttt ccaaaagagc ccgcccaatt tccttaatca cgatattggg
    37261 caaaatagag gtaaagaggg aacctggccc taggacaatc atgtcacttt caaggatggt
    37321 ctgcactact cgacggctgg ccagaggcgt atcatcgttt agggcattgg tcacatagac
    37381 attgtcaatt atgcctcgat ggtctacaat atgactctct ccagccactt ctgtcccatc
    37441 ctgaaagact gcatgaaggg tcaaaggatg gtcactggaa ggataaattt tccctgttgt
    37501 atggaaaaat ttgctcaata actgcatggc attataggtt gaaccctgca tttctgacaa
    37561 gccagcaatg atgagatttc ccaatggatg gccagcaaag gctccggcat cctcagagaa
    37621 ccgatactga aagaccttct cataaaactt aggcatatcc gacatggcca caaggacatt
    37681 acgaagatca cctggcggtg tcaactgttg catatttttt cggagttcac ctgaagaacc
    37741 accatcatct gccaccgtca cgatagctgc gatttccaca tctttttccc gcagactttt
    37801 tagaatgacg ggaattccag tccctccacc aatcaccgtt atctttggtt ttctcatgaa
    37861 cggtttaccg tttcctttct gcggtctttg tcgcgatgcc cttcattaac agaccaattc
    37921 ttggataagt cctgcgccaa gcgtttagca aatgccacac tacggtgttg tccacccgta
    37981 catcccatag caatggtcaa aacggactta ccttcctttt ggtaacttgg cagaatcggc
    38041 tcaatcaagg ccaataaatg ttgataaaag tcttctgact caggatggtt catgacataa
    38101 tcataaacag gttcatccac acccgtttgg tttctcagtt ctggtagata atagggattt
    38161 ggcaagaaac ggacatcaaa gaccaagtcc gcatcaatcg ggattccata cttaaatccg
    38221 aaagacatga cttcgatacg gaaagactgg gcttgttctt ggtctgaaaa ctgctctgca
    38281 agggttttgc gcagttcacg tggagtgagt tcagtcgtat ccaccacatt ttggctcata
    38341 tttttcaaag gtgccaagag ttcacgttcc aacttgattc catctaaaat acgaccgtct
    38401 gctgctagtg ggtgactccg tctggtttcc ttgtaacgag cgaccaattc cttatcagcc
    38461 gcatccaaaa agaggatttt gaaatccaaa ccatcttgat tttccaactc atccaaaaca
    38521 gcttgaatct ctgaaaagaa agaacggcta cgcatatcca ctaccaaagc caacttagga
    38581 ttatcttcct taatttcaac cagctgcaaa aacttaggca agagagctgg cggcatatta
    38641 tcaatggtga aataacctag atcctcgaag gactgaatgg ctacagtttt ccctgcgcca
    38701 ctcatccctg tcacaatcac caagtgaagt tgtttctttg tcatcttttt ctccttatat
    38761 caaaagaagt ttggcaacac caaacttcaa ctagcttatc caatctctgc gatgacttca
    38821 atttcgactt ttacatcacg aggaagacga gctacctcca cagctgaacg agctgggaat
    38881 tcctctttga aggccgtttg gtaaacctca ttaaaaggaa caaagtcgtt catatcgctc
    38941 aagaagcaag ttgttttgac aacatggtca aagtctgttc ctgcttctgc caaaatagca
    39001 ccgatgtttt tcaagacttg ctctgtctgt tcttggatat tctctcctac aatttcccca
    39061 gtttcagggg ataggggaac ttgaccgcta gcaaacaaaa ggttgccaac gatttttcct
    39121 tgaacatagg gtccgatagc ctttggggcc ttatctgtat gaattgtttt tgccattttc
    39181 ttttcctcac aatttttcta agattgcatc ccaagcctca tccatccctg ccttgctgac
    39241 agatgaaaag aggatgaaat cgtcactcgg gtcaaagttt aatttctttt tgattgctga
    39301 ttcatgcttg ttccatttac cacgaggaat cttgtccgcc ttggtcgcca caatgatgac
    39361 tggaatctca taatacttga gaaattcgta catctgcaca tcatctgctg acgggtcatg
    39421 acgaaggtca actagactga caaccgcacg gagattttcc cgagtcgtta agtactcctc
    39481 aatcatgcac ccccactttt cacgttcctt tttagaaaca cgagcatagc cataaccagg
    39541 cacatccaca aagcgcatct tgtcatcaat gttaaaaaag ttcaggagct gggttttacc
    39601 aggttttcct gatgtacggg cgagattctt acggttcaac atagtgttga taaagctgga
    39661 tttaccaaca tttgaacgcc ctgctagggc aatctctggc agttcatcct gcggatagtg
    39721 ggacttatta gctgcactga gcaagatttc agcattgtgt gtattaagtt ccatagtcac
    39781 ctctaggctg tttctaggat cggtttatcc gttccatcga cagtttcttt agtgatgcga
    39841 accaatttca cattttcctg actcggcacc tcaaacataa catctagcat ggtttcttcg
    39901 atgatggagc gaagtccacg cgcccctgtc ttccgttcga ttgctttatt agcaatctct
    39961 tgaagggctt cgtcgtcaaa ttccaactca acatcatcat aagaaagcaa ggtttggtat
    40021 tgtttcacca aggcatttct tggctctttc aagatgcgaa ccaagtcatc aacggtcaat
    40081 tgctcaagag ccgcaaaaac aggcaagcgt ccaatcaact cagggataat accaaatttt
    40141 tgaatgtctt cagcgatgat ttcttgcatg tatgagctgt tttcgtcaat cgccttattg
    40201 ttttgaccaa atccgatgac tttttcaccc agacgttgtt tgacaatttc ttcaatacca
    40261 tcaaaagcac cacccacgat gaagaggata ttttttgtat ccacttgaat catctcttgt
    40321 tgtggatgtt tgcgtccacc ttgaggcggt acgctagcaa cagttccctc gataatcttg
    40381 agaagggctt gttgcacccc ttcaccagaa acatcacgtg tgatagacac attctcactc
    40441 ttcttggcaa tcttgtcaat ttcatccaca tagataatgc cacgctctgc acgttcgatg
    40501 ttaaagtcag caacctgcaa gagtttgagg aggatatttt ccacatcctc acccacataa
    40561 ccagcctccg tcagagctgt cgcatccgca atagcaaaag gtacattcaa gctcttagcc
    40621 aaggtctggg caaggaaagt tttccctgaa ccagttgggc caatcatcaa aatgtttgac
    40681 ttctgcaaat ccacatcttc tgactcttcg cgtgtatcgt ggaaattgat gcgtttgtag
    40741 tggttataaa ccgccactgc caaggcacgc ttggcacgat cttgaccaat tacatagtgg
    40801 ttcaagatat ggaggagttc aattggtttt ggcacctcag acaagtctgc caagacttcc
    40861 tcaaccaatt cttctcgaat gatttcctga gctaactcca cgcattcatt acaaataaaa
    40921 gcattgttgc cagcaattat tttttgtact tcttcttggt ttttgccaca aaatgagcaa
    40981 taaaccatca tatcattttt tctatttgta gacatgattt ccttccattc tatactgtca
    41041 ttctatctaa aataaggtca tgtaaaaagc atgaatacta ttgaccagat tggtaaaggc
    41101 atttaaccaa aggaggatag aaagcccgta acgcttttta cgaaaagctt gtgctcctgc
    41161 cagaaagcag atgaaacaca gaaaagccgt gaatagacca aataaactcc gttccattag
    41221 acttcctttc tcttgcggta ttggatggta aaatcataag gattcttctc atctttggcg
    41281 taaaatttgc ttgaaactgt ctcaaaaaga gacaagtcaa gttcttcagg gaaataggta
    41341 tctccttcca cccgagcatg aatgtgagtg acaatcactt catcaaggta aggttcaaaa
    41401 gcctgaaaaa tttgcttccc accgataatg tagagattct tttcttgagc ctgataccag
    41461 tcaagaacag actggacgtc ctgaaaagta gcaaccccat ctatcttttc ttccggatta
    41521 cgcgtcaaaa tcaaggtttc ccgttttgga agcaagcgac gccccatccc atcaaaggtc
    41581 acacgcccca tcaagatagc atgattcaga gttgtttctt taaagtgctg caattctgct
    41641 gacaaatgcc aaggcagacg attttcctta ccaatcacac cctcttcatc ctgggcccaa
    41701 atagctacga ttttcttagt catgcttcca tccttttcac tgatagtact attttatcaa
    41761 aaaactcaaa aaaagactgg tttggaatag cttacaaaat agaaaaaatc tgtaagaaat
    41821 ttcctacaga tttatctatg tttccttatt tcttacaaac caggtgcttg tccaagttcg
    41881 gctgcaagca tccaaattgt tttatctgtt tcagttttag cgcctgcaaa gataccgttt
    41941 gtcacatcgt caccttcttc atcagtgaca tccaaacctt tttggaaaag ttctgacaag
    42001 taacggtaga taacaagaac acgttccaag ctttcttcaa cattacggta ttcaccagct
    42061 tcttcttcga tttcactatt ttgaaggaac tctgtcaatg tagagaatgg gcttccaccg
    42121 agtgtaatca agcgttcgct gatttcatcc aattgaccgt caagagcttc catgtactca
    42181 tccatttttg gatgccatac aaggaaacca cgaccatgca tataccagtg cacttggtgc
    42241 aaagcaacgt gagctacata caaatcagca acagcttggt tcaagacttc ctttgttttt
    42301 gccaatgcta ctggcgctgc ttttgtcaat gatgttacgt cttttactgc ttcttttttc
    42361 aattctacca ttttctttac ctcattcatt attttttgta accacttctt aatgattact
    42421 accttagtat actactaagg aaaaccaata gcaagacaaa gaacttatat gagaaaagtt
    42481 gcaatagact gataatttaa gaattcttta gaagacaaaa aagagggttg gatgcttata
    42541 gtcaatggaa atccatcagc aaactaggaa actaaaccca gcttgaccaa agcacaagtt
    42601 ttgaggtcgc aggtagaact gaccaagctg atgtggtttg aagaaattcc ccaatactat
    42661 aatagattga aataagatga aaccaagtcg attaggaaag gtaaatgaat ttctaaaatg
    42721 ttttaccaat cacaaggtct ttgtctatat tcaatctact atataagctt catttccgag
    42781 caagatcttg aatttactcg aggatgaact atcataaaac gactctataa tatttgtagt
    42841 gggtaaatcc actatagata ttatggagcc tattttattg tagaaaaaaa gtcccataag
    42901 atctataatg aaaagcgacc aaacaactca ttagaaagat tcatatggaa caattacatt
    42961 ttatcacaaa actactcgat atcaaagaca caaatatcca aattatagat gtcgtcaata
    43021 ggga
//
LOCUS       DAVLDI010000013        41249 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLDI010000013 DAVLDI010000000
VERSION     DAVLDI010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41249
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.013"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..603)
                     /locus_tag="VXD01_000682"
     CDS             complement(<1..603)
                     /locus_tag="VXD01_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="HEV0601116.1"
                     /translation="MTIKINYMFFVCLSFFGIVLSSSQVIVNLGLSSIVQYIAYFLLL
                     LCIFFTLIKNSPDVIANRIAYFSIISFLFIIGINLQNLPFSTKIYLSFSMLIISSLST
                     LPIKLINNINDFRRISYFLLNGILLSTFLGWLFNISLVTVAVEGIGFAYGFNGGLTHK
                     NFYAITILVSYILLFISRKHGTKYQVDSLVLWFDLFLLLVS"
     gene            complement(904..2082)
                     /locus_tag="VXD01_000683"
     CDS             complement(904..2082)
                     /locus_tag="VXD01_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV0601117.1"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNDAICYNIDVPNIGPARAIAYDIAAVNKAIEIAKKNKDEAPIF
                     YILACRIGPFIARLKKKIQAIGGTLFVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKYA
                     DLLVCDSKNIEKYIQNDYKQYQPKTTYIAYGTDTSPSILKSEDLKIRSWYQEKGLSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSKKDFVLITNVEQNKFYDQLLQETGFDKDPRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWRKDNLHKVIEESEQKTIEEIKEIDILSTEQVEKRFTWDFIVNEYENLFLLGK
                     "
     gene            complement(2114..3475)
                     /locus_tag="VXD01_000684"
     CDS             complement(2114..3475)
                     /locus_tag="VXD01_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0601118.1"
                     /translation="MNEKLAKSSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYIL
                     HYFVFYISDYGRNFFKRRYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LLLHVFLVYMLNLFIKWYWKRAYPNFKGSKKVFLLTATSHVEKVLDRLIESDDVVGEL
                     VAVSVLDKPDFQHDDLKVVAEGEIVNFATREVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDWARNKQICEMAGLNVVTFSTTFYKTSHVIAKRVIDIIGSLVGLILCG
                     LVSIVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMCVDAEDKKRELMEQNTMQG
                     GMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQK
                     RRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVVYIDGWTIWKDIEILLKTVKVVLMKD
                     GAK"
     gene            complement(3490..4179)
                     /locus_tag="VXD01_000685"
     CDS             complement(3490..4179)
                     /locus_tag="VXD01_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV0601119.1"
                     /translation="MPTLEISQAKLELAKKTEEYYNALCTNLQLSGDDLKVFSISSVK
                     AGEGKTTTSTNIAWAFAHAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPIALLQSKNFSTMLGTLRKYFDYIVVDTAPIGIVI
                     DAAIIMQKCDASILVTKAGETKRRELQKAKEQLEQTGKSCLGVVLNKFDTSVDKYGFY
                     GSYGSYRKQKK"
     gene            complement(4189..4881)
                     /locus_tag="VXD01_000686"
     CDS             complement(4189..4881)
                     /locus_tag="VXD01_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEV0601120.1"
                     /translation="MKEQNTIEIDVFQLLKTLWKNKLIILLVALVTGAGAFAYSIFIV
                     KPEYTSTTRIYVVNRNQENKPGLTNQDLQAGTYLVKDYHEIILSQDVLEKVATNLKLD
                     IPVKTLTSKVQVTVPADTRIVSISVKDKQPEEASRIANSIREVAAEKIIAVTRVSDVT
                     TLEEARPATTPSSPNVRRNTLVGFLGAAAVTVITVLLIELFDTRVKRPEEVEDVLQMP
                     LLGVVPDFNKMK"
     gene            complement(4890..5621)
                     /locus_tag="VXD01_000687"
     CDS             complement(4890..5621)
                     /locus_tag="VXD01_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV0601121.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLGKLEKNRIPTLNNS
                     RYALIEFSMNTPYRDIHSALIKILMLGITPVIAHIERYDALENNEKRVRELINMGCYT
                     QVNSSHVLKSKLFGEPYKFMKKRAQYFLERDLVHVIASDMHNVDSRPPHMAEAYDLVS
                     QKYGETKAQDLFIDNPRKIVMDQLI"
     gene            complement(5623..7068)
                     /locus_tag="VXD01_000688"
     CDS             complement(5623..7068)
                     /locus_tag="VXD01_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0601122.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYFNLVVTALVLLVALVGLLLIIHKKAAKFTIFLLVLSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNIDLT
                     VNQSSSYLATYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDIHYYVRLNFTSFLKLIDLLGGVDVYNDQ
                     DFTSLHGKFHFPVGNVHLDSEQALGFVRERYSLADGDHDRGRNQQKVIAAILQKLTSS
                     EALKNYSMIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGRGRTDLPSY
                     AMPDSNLYMMEINDSSLASVKTAIQDVLEGR"
     gene            7245..8630
                     /locus_tag="VXD01_000689"
                     /pseudo
     CDS             7245..8630
                     /locus_tag="VXD01_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
     gene            8578..9412
                     /locus_tag="VXD01_000690"
                     /pseudo
     CDS             8578..9412
                     /locus_tag="VXD01_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9490..11100)
                     /locus_tag="VXD01_000691"
     CDS             complement(9490..11100)
                     /locus_tag="VXD01_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV0601123.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDFLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLAQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEEINVQEALANSDSIFYTYQKL
                     IQIRKENSWLIRADFKLLDTADKVFAYIRKDGDRRFLVVANLSNDKQNFSVDGKVRSV
                     LIENTAAKEVLEKQVLTPWDAFCVEMTD"
     gene            11253..12737
                     /locus_tag="VXD01_000692"
     CDS             11253..12737
                     /locus_tag="VXD01_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV0601124.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            12832..13314
                     /locus_tag="VXD01_000693"
     CDS             12832..13314
                     /locus_tag="VXD01_000693"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV0601125.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(13610..15715)
                     /locus_tag="VXD01_000694"
     CDS             complement(13610..15715)
                     /locus_tag="VXD01_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV0601126.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(16324..17304)
                     /locus_tag="VXD01_000695"
     CDS             complement(16324..17304)
                     /locus_tag="VXD01_000695"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV0601127.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIKFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLIASVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVVFYLFYERGGDMLSVFGYQVHLGIFYILFALFWLVGF
                     SNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(17306..19558)
                     /locus_tag="VXD01_000696"
     CDS             complement(17306..19558)
                     /locus_tag="VXD01_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEV0601128.1"
                     /translation="MKWTKKVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGSKGNGITY
                     ANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQ
                     MNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTKDFVWRDILYQSNYE
                     PGSTMKVMTLAAAIDNNTFPGGEVFNSSELKVADATIRDWDVNEGLTGGGMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGIPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFITALYDPNNQSVRKSQKEIVGNPVSKDAA
                     SQTRTHMVLVGTDPRYGTMYNHSTGKATVNVPGQNVALKSGTAEIADEKNGGYLVGST
                     NNIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERAVAMKDSLNLQSTA
                     KTLDQVTNQSAYAMPSIKDISPGDLAEALRRNIVQPIVVGTGTKIKESSVEEGSNLAP
                     NQQVLLLSDKAEEVPDMYGWTKATAEAFSKWLNIELVFEGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(19562..19879)
                     /gene="ftsL"
                     /locus_tag="VXD01_000697"
     CDS             complement(19562..19879)
                     /gene="ftsL"
                     /locus_tag="VXD01_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV0601129.1"
                     /translation="MAERMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(19891..20841)
                     /gene="rsmH"
                     /locus_tag="VXD01_000698"
     CDS             complement(19891..20841)
                     /gene="rsmH"
                     /locus_tag="VXD01_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV0601130.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQQRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQEASLTAYEVVNHYDYHDLIRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMEMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            21007..21201
                     /locus_tag="VXD01_000699"
     CDS             21007..21201
                     /locus_tag="VXD01_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0601131.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            21217..21759
                     /locus_tag="VXD01_000700"
     CDS             21217..21759
                     /locus_tag="VXD01_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV0601132.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKAGITAIDPDMLSEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLGILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKDPDED"
     gene            21769..22011
                     /locus_tag="VXD01_000701"
     CDS             21769..22011
                     /locus_tag="VXD01_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601133.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTIIFFIIPPIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            22022..22357
                     /locus_tag="VXD01_000702"
     CDS             22022..22357
                     /locus_tag="VXD01_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601134.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(22467..23468)
                     /locus_tag="VXD01_000703"
     CDS             complement(22467..23468)
                     /locus_tag="VXD01_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0601135.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(23528..25429)
                     /locus_tag="VXD01_000704"
     CDS             complement(23528..25429)
                     /locus_tag="VXD01_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV0601136.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPHSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYHFFADKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPRSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(25451..25744)
                     /gene="yajC"
                     /locus_tag="VXD01_000705"
     CDS             complement(25451..25744)
                     /gene="yajC"
                     /locus_tag="VXD01_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0601137.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIHVEKESVMGKTKELLFK"
     gene            complement(25744..26562)
                     /locus_tag="VXD01_000706"
     CDS             complement(25744..26562)
                     /locus_tag="VXD01_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0601138.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(26549..27328)
                     /locus_tag="VXD01_000707"
     CDS             complement(26549..27328)
                     /locus_tag="VXD01_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV0601139.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFVFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(27343..27834)
                     /locus_tag="VXD01_000708"
     CDS             complement(27343..27834)
                     /locus_tag="VXD01_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV0601140.1"
                     /translation="MTMPNIVMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKNVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKVALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(27845..29035)
                     /locus_tag="VXD01_000709"
     CDS             complement(27845..29035)
                     /locus_tag="VXD01_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEV0601141.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(29047..29481)
                     /locus_tag="VXD01_000710"
     CDS             complement(29047..29481)
                     /locus_tag="VXD01_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0601142.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVVAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            29753..30568
                     /locus_tag="VXD01_000711"
     CDS             29753..30568
                     /locus_tag="VXD01_000711"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV0601143.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIQAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            30587..31228
                     /locus_tag="VXD01_000712"
     CDS             30587..31228
                     /locus_tag="VXD01_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV0601144.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            31259..32260
                     /locus_tag="VXD01_000713"
     CDS             31259..32260
                     /locus_tag="VXD01_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV0601145.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISALEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKETYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            32270..32899
                     /locus_tag="VXD01_000714"
     CDS             32270..32899
                     /locus_tag="VXD01_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV0601146.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(33278..33663)
                     /gene="tnpA"
                     /locus_tag="VXD01_000715"
                     /pseudo
     CDS             complement(33278..33663)
                     /gene="tnpA"
                     /locus_tag="VXD01_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(34016..37219)
                     /locus_tag="VXD01_000716"
     CDS             complement(34016..37219)
                     /locus_tag="VXD01_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV0601147.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIETKDG
                     TITISSPEKLRAALHRMVPIEAKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WLHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKSPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKGINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            37442..37918
                     /locus_tag="VXD01_000717"
     CDS             37442..37918
                     /locus_tag="VXD01_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV0601148.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            complement(38140..40353)
                     /locus_tag="VXD01_000718"
     CDS             complement(38140..40353)
                     /locus_tag="VXD01_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV0601149.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(40754..40930)
                     /locus_tag="VXD01_000719"
     CDS             complement(40754..40930)
                     /locus_tag="VXD01_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601150.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
BASE COUNT        12373 a         9067 c         7209 g        12600 t
ORIGIN      
        1 agatactaaa agtaaaaaaa gatcaaacca taatactaag ctatcaactt ggtacttcgt
       61 accatgtttt ctactaataa acaataggat ataggaaact aaaattgtaa ttgcataaaa
      121 attcttatgc gtcaacccac cattaaatcc atatgcaaaa ccaatcccct caacagcaac
      181 agttactaat gaaatattaa atagccaacc taaaaatgtt gataatagga tgccatttaa
      241 taaaaaatag gatattcttc taaaatcatt tatattattt attaatttaa tcggtaaagt
      301 cgatagacta gaaataataa gcatggaaaa cgataaataa atctttgttg agaaaggaag
      361 attttgtaaa ttaatcccta tgataaacaa aaatgaaata atagaaaaat aagcaattct
      421 attagcgatt acatccggac tatttttaat taaggtaaaa aatatacata gcaacaataa
      481 aaaataagct atatactgaa ctatactgga caaacccaga ttcactatta cctgtgaact
      541 acttaaaact ataccgaaaa aagagagaca aacaaaaaac atataattaa ttttaatagt
      601 catacttgat acctttgact aaatgacaat atagaataag aacacgtttt tgatttaata
      661 agaactactt atttcttaaa tctccaccag tttgtcttaa aactatgtcg tttaacccta
      721 cccaaaaaca ctatcaacta ctgggcatat ttcctctcta taattttagt atctttgcaa
      781 aaagggagaa tatctatcat tttaaaaact tcatgaataa cataagttat ttagataatt
      841 gtctaagaaa gtgatgaact tccatcaaag cttcctcaaa taaaatcctt gtaacttaga
      901 taattatttc cctagtaaaa ataaattttc atattcatta acaataaaat cccaagtaaa
      961 tcttttttct acctgctctg tagatagaat atctatttct tttatttctt ctattgtttt
     1021 ttgttcactc tcttcaataa ccttatgaag attatctttt ctccaataaa tagccccgtc
     1081 ttcaccaacc tcacggttaa aaccaacatc tagcaacaaa ttcagttttg tggatgctag
     1141 agcttctagt agagaagggt tggtccctcc aacctcatgc ccatggaaat aggcaaaagc
     1201 attttcacga atgtacttaa gcaattcttg gtcatagaca gtacctacaa atttaaccct
     1261 aggatctttg tcaaaaccag tctcctgtaa caactggtcg taaaatttat tctgctccac
     1321 atttgtgatg aggacaaagt ccttcttgga cttagatttg ataaattcac gaatcatggt
     1381 ttcgtagttg ttttcaggga cgaatcgtcc caccactaga taatagccat tttcgctaag
     1441 tcctttttcc tgataccaac tacgaatttt tagatcttcg gatttcagga tagacggact
     1501 tgtatccgtc ccgtaagcaa tataagtcgt ctttggttga tattgcttat agtcattctg
     1561 gatatatttt tcaatatttt tgctatcaca gaccaataaa tctgcatatt tgaccatcaa
     1621 ctgttccgaa aatttccaat actttcgaac cggcaggctc catttagccc gaagccactc
     1681 atgtccatct ggattgacaa acagagtacc tccgatagct tgaatctttt tcttaagtct
     1741 agctataaaa ggcccgatac gacaagctag aatgtaaaaa ataggagctt catctttgtt
     1801 tttcttagct atttcaatcg ctttattcac agcagcaata tcataagcaa tggctctagc
     1861 aggaccaata ttaggcacat caatgttgta acaaatagca tcattgtact caaatgtatc
     1921 tgctgtaaat cctgattttg cagaattttc gcgcatgcag gcaacatagt attggatgtt
     1981 accatctttt tgatattctg ttaatttctc aacaaaggtt tcaaagcccc catacttagc
     2041 gggaatccct tttgaaccaa tgatataaac tgacttcttc atttttctcc taatagtctg
     2101 aaacaaaagc aaactatttc gctccatcct tcatcaatac aactttaact gtcttcaata
     2161 aaatttcaat atctttccag attgtccaac catcaatata gaccacatct aatttgacaa
     2221 cttcatcgaa atttttgatt tcacttcgtc cactgacctg ccataagcct gttataccag
     2281 gtttaaaact tagccgacgt ttttgttctg gggtatagtg ttcatactcg tccactgttg
     2341 gtggtcgtgt acctaccaaa ctcatatctc cctttagaac attataaaac tgtggtagct
     2401 cgtccaagct cgtcttccgt ataaaatgac caattttcgt gatacgagga tcatcgtcca
     2461 ccttaaacat tccaccctgc atggtatttt gttccatgag ttctctcttt ttatcctcag
     2521 catctacaca catagagcga aacttgtaaa aagtgaaatg gcggccattt tttcctatac
     2581 gcgtctgagc aaaaatagca gagcccccat cctttcgaat caaaggaacc agcacaatac
     2641 tgactagacc acatagtatc aaacctacca gggaaccgat aatatcaata acccgcttag
     2701 caatcacatg gctagtctta taaaatgttg tagaaaaagt cacaacattt agtcctgcca
     2761 tctcacaaat ttgcttgtta cgtgcccaat cgaaagcatt tagattgact gttacatcaa
     2821 ttcccatcgt ttcaaactga gagacaagct ctccaatatt gtatttttca cttggaagat
     2881 tgataaagac ttcatcgacc acctcacgag tcgcaaagtt tacgatctcc ccctctgcta
     2941 caacctttaa atcatcatgc tgaaaatctg gtttatctaa aacactgacg gctaccaact
     3001 ccccaacaac atcatctgat tctattagtc tatccagtac cttttcgaca tgagaagttg
     3061 ctgtaagtag gaaaaccttc ttacttcctt taaagttggg ataagcccgc ttccaatacc
     3121 acttgataaa taggtttagc atatagacta agaaaacatg taataggagg aagtaaatca
     3181 tgcctcgtct ggaaatacta aatcgatcct ctaagaaaaa attagaaata ctaatcgcta
     3241 gcgcaaagaa taggatatat ttcaatgtct ggacaagttc aatcaaatat ctccttttaa
     3301 agaaattccg tccataatca ctgatataaa agacaaaata gtggaggata taaagtacaa
     3361 tagctgttgt tgaaacaatc tctgtttctc tcacagcgct aagtagataa gtcaataaaa
     3421 taacaagaaa actctggact atagctactg aagactttgc tagtttttca ttcatctcta
     3481 tccctcaacc tattttttct gtttcctgta actcccataa ctcccataaa aaccgtattt
     3541 gtctactgaa gtatcgaatt tattcaacac aactcctaaa cacgacttcc cagtttgttc
     3601 caactgttct ttcgcttttt gaagttcccg tcgttttgtt tcacctgcct tcgtcactaa
     3661 aatagaagca tcacatttct gcataatgat agccgcatca atcacgatac cgataggagc
     3721 agtgtctacg acgatatagt caaaatattt acgcaaggtt ccaagcattg tactgaaatt
     3781 cttactttga agaagggcta tcggatttgg tgacacagag ccagcctgaa tcacaaagag
     3841 attctcaaca ttggtatcgc aaagcccctg tgacaggtct gttgtccctg atagaaattc
     3901 tgttagccca gtaatccttt cccttgattt aaagacacct gacataacgg agttacgcat
     3961 gtctgcatca atcagcagcg ttttgtaacc tgcatgcgca aaagcccaag cgatattggt
     4021 ggaagtcgtt gtttttcctt ctcctgcttt cacagaactg atagaaaata ctttcaaatc
     4081 atctccactt aactgtaggt tcgtgcacaa agcattataa tattcctctg tctttttcgc
     4141 aagttctaat ttcgcctgtg agatttctaa cgttggcata acttcctcct atttcatttt
     4201 attaaaatct ggaacgactc ctagaagtgg catttgcagt acatcttcaa cttcttcagg
     4261 acgttttaca cgggtatcga acaactcaat caaaagaaca gtaattactg ttacggcggc
     4321 ggctccaaga aaaccaacta aggtgttgcg tcgaacattt ggagaagagg gagtcgtagc
     4381 tggtcgcgct tcttcaagcg tcgttacatc agatactcgc gttacagcga tgatcttttc
     4441 tgcagcaact tctcgtatag aattagcaat gcgactggct tcctctggtt gtttatcctt
     4501 gacagagatt gagacgatac gagtgtcggc tggtacagtc acttgcactt tgctagttaa
     4561 cgtttttact ggaatatcca atttcaaatt tgtcgctacc ttttccaata catcttgcga
     4621 aaggataatt tcgtggtagt cttttaccag ataagttcct gcctgcaagt cctgattcgt
     4681 cagtcccggc ttattttctt gattacgatt gactacgtaa atacgcgtgg tgcttgtata
     4741 ttctggctta acaataaaaa tgctatatgc aaaagctccc gcccctgtca caagtgccac
     4801 taataaaatg attagcttgt ttttccacaa ggttttaagt aattgaaata catcgatttc
     4861 tatcgtgttt tgttctttca ttatttctcc taaattagtt gatccattac aatttttcga
     4921 ggattgtcta taaaaaggtc ctgagccttc gtttctccgt atttttggga aacaaggtca
     4981 tatgcttctg ccatatgggg aggtctgctg tccacattat gcatatcact tgcaatcaca
     5041 tgaaccaaat cacgctccaa gaaatactga gctctttttt tcatgaattt ataaggttct
     5101 ccaaaaagtt tggatttgag gacatgtgaa ctatttactt gcgtgtaaca gcccatatta
     5161 atcagctctc gaacgcgttt ttcattattt tcaagagcat catagcgctc gatgtgggca
     5221 atgactggag taattcccaa catcaatatt ttaatcaagg cactatgaat atcgcgataa
     5281 ggggtgttca tactaaactc tatcaaggca taacgactat tattgagggt cggaatccga
     5341 tttttttcca gcttacccaa aacatctggt gtgtagtaaa tttcggcccc ataagcaatg
     5401 accaagtcac tcgcgacttc cttagctatt tcccgaacct gaagaaagtt ttctgctatc
     5461 ttctcttctg gagtttcaaa catgcccttg cgacggtgag aggtagagac aatggttcgc
     5521 accccctgcc tgtaggcttc tgtcaagaga gccttacttt cctctcttga cttgggacca
     5581 tcatctacat caaagacaat gtgcgaatga atatcaatca tttcatctgc cctccaacac
     5641 atcctgaata gcagttttga cagatgcaag gctactgtcg ttaatttcca tcatatagag
     5701 gttactatct ggcatcgcat aggaaggaag atccgtccgt cccctaccct tcaagtcttg
     5761 cgaatttact ttgtacgttc caccactttc taactgagca ttgaccaagt ttatcatggt
     5821 ctcaaggggc atgtttgttt ggatagaatc ttgcaagcta tcaatgatca tactataatt
     5881 tttcagcgct tcgctcgaag ttaatttttg aaggatagcc gcaatcacct tttgttgatt
     5941 gcgcccgcgg tcatgatcac catccgctag ggaatagcgc tcacgaacaa atcccagagc
     6001 ctgctcagaa tctaagtgga catttccaac tgggaaatgg aacttcccgt gtagagatgt
     6061 gaaatcttgg tcattataaa catctacccc acccaacaaa tcgatcaatt tcaagaaaga
     6121 agtgaagttc aaacggacat agtaatggat atccactcca tagagatttt ctaaggtgtg
     6181 aatggacgaa tcaactccat agatgcccgc atgggtcaat ttatcttttt gattattccc
     6241 accatctgcg attggtacat aagcatcacg tggcgttgtg gtcaagagaa ttttcttggt
     6301 atctcgattg acagtcatca ggatattgac atctgaacgc gacaccgaac taatcggacc
     6361 ataagtatca attccactaa catagatatt gaaagactga ttcttagacg tcttaggagc
     6421 ttctactttt ttagtgaatc ccttggtata aatctttttt atcttcgatg cgtaatctgg
     6481 atactccgat tcgatgatat tttcaaagac actatttaag acaatggcct tagtctctcc
     6541 tgcaatcaaa ctcttgtaag ttgccaagta agacgaactt tgattgaccg tcaaatcgat
     6601 attctgactt gatttgatat cagctagtag tttttgaatg ttttcattat cagtcccagt
     6661 cggtgctgtc acactcgtca gttgcgtaac attctcaatc tcactatctg ctaaaacagc
     6721 gacactgatc gaatattctg agtaattaga agtcgcattt aaacgattgg tcagtcccac
     6781 aaactgctgt actgcaaaga gcgacacaga gctgacaaga atagagagca ccaacagaaa
     6841 aatagtaaac tttgcagctt ttttatggat aatcaagagt agccctacca aggcaactag
     6901 taggactaac gcagttacca ctagattaaa atatctaaaa gcaaggatat tgtacttaaa
     6961 gattaagaac aataaaaaac aaactaacaa taaataaata gtcaacaaaa ctatattaac
     7021 acttcgcttc actttctgtg aacctgattt tttaaaacgt ctactcatga ttaacaccta
     7081 tacattgaac atcttacaat tatatcactt ttttacggta atgtctacac ctttttttca
     7141 ctatctgcat cttgtgtaat tcgaatgtga taatgtcttt agtaaatcga acgtaaaaat
     7201 gtcccatttg gtagaatagt catatgtaaa ggatccaact gaatatgaat gaaacgaaaa
     7261 aatatcttgt gataaaagct atagcccaag gaaagaaaac aaagaaacga gcctgtgtcg
     7321 agctcaatct ttctgaaagg caaatcaatc gtctgctact agcctatcaa cagaaaggaa
     7381 aagaagcctt cagacacgga aacagaaatc gaaaaccaaa acatgcaatc cctgatgaaa
     7441 tcaaagaacg tatcctaaag aaatacctct cctatgaaac atataaacca aatgtccgtc
     7501 atttctgtga attgctagct gaagaagaag gaattcagct ctctgataca actgttagaa
     7561 aaatactcta taagaaaaat atcctgtcgc ctaagtccca tagaaagaca aagaagagag
     7621 taagaaagca agctaaactg aaccccaagc aacccctaga caatccaatc ttaccgacgg
     7681 ctgaaaactt cctggaagac cctaaaaagg tacatcctag tagacccaga aagaaatttg
     7741 ctggagaact catccaaatg gatgccagcc ctcatgcctg gtttggagca gaaacctcta
     7801 acttacacct agccattgat gatgcttctg gcaatatcct aggcgcttat tttgacaaac
     7861 aagagacctt gaatgcttac tatcatgtcc tcgaacaaat cttagccaac cacggcattc
     7921 ctgttcaaat caaaacagat aagagaactg tttttaccta tcaagcctcc aactctaaga
     7981 aaatggagga cgacacccat acacaatttg gatacgcctg tcaccaactg ggaattctcc
     8041 ttgagacaac ctctatccct caagctaaag ggagagtcga aagactcaat cagatactac
     8101 aatctctcct gcctatcgaa ctggaacgaa acaagattca taccttggaa gaagccaata
     8161 cctttctgcc ttcctatatc caaaccttta atgaacagtt tggaaacaag acaaaactct
     8221 ctgtctttga ggaggctcct aagccctctg aacgaaatct cattctagct aaactggcgg
     8281 gagagagtcg tcgatagtgg acaccatatc cgattccaaa atcgttgcta tatccctacc
     8341 gagcaaggaa aagaagtcta tttcatcaga aagacaaaag cattagttat aaaagcattt
     8401 gatggtgaca tctacctcaa tatcgctgac aaaatctatc acacaaagga gctactaaat
     8461 catgaactct attcgaaaaa ccttgaacaa gaaccagaac aaaaaaagaa agacgcaagt
     8521 atatccctcc acaaacccat ccgtggaaac tcacatcttt caaacaatat cttcataaaa
     8581 ataaaaagga ttatgaagag tttaaaggag gatttttcag tacgtgctga aaaatatgag
     8641 aactatcagg agacatttca agggcctaac agtttttcca aaaccgatcc agatgccact
     8701 tttatgcgga tgaaggaaga acatatgaaa aatagtcaac ccaaggctgc ttataatctt
     8761 caaatcgcta cggaaaacca atttgttctt cactatgatg tcttttcaaa tccgacagat
     8821 accaagactc ttctgccatt ccttgaaacc tatccgcatg acttgaagac agttgtcgca
     8881 gatgctggat atggaagtga agagaacctc cttcgtttag atgaaaagga ggtaaaccat
     8941 ctgattaaat atgccatgtt tgataaggaa cagaagagag gctataaaca gtcagctaga
     9001 aacttagcga attggcacta taatgacaag gaggatagct atacacatcc tgatggctag
     9061 tattatcgtt ttcaccatac caaacatcag aaaacacaga cagactttca acaagaaatc
     9121 aaggtttact acgtcgacga acctgaatca gcccctcaaa aggggactgt atatgaacga
     9181 aggctatcaa aacttgaaag ctaaagaatg tcaggcgctt ttatctcccc aaggtagaca
     9241 gattttcgct caacgcaaga ttgatgtgga acctgtcttt gggcagataa aggcttgttt
     9301 gggttacaag agatgtaatc tgaggggcaa gcgtcaagtg agaattgaca tgggattggt
     9361 acttatggcc aataacctcc taaaatacaa taagagaatg actcaaaatt aaaaagctag
     9421 agttccacaa ttggaaatct ctagcttttt tgtggtcgag aactattttg tcccaggctc
     9481 ttgctcattc tagtcagtca tttccacaca gaaagcatcc catggagtca agacctgttt
     9541 ttcaagtact tctttagccg cagtgttttc aatcaagaca gatctaactt ttccatctac
     9601 tgaaaagttt tgtttatcat tggataaatt agccacgact aggaagcgac ggtcaccgtc
     9661 cttacggata taagcaaaga ccttatcagc cgtatcgagt aatttaaaat cagctcgaat
     9721 caaccagctg ttttccttac gaatctggat gagtttctga taggtataga aaatagaatc
     9781 tgagtttgcc agtgcttctt gaacgttgat ttcttcgtag tttggattaa ccgccaacca
     9841 aggttgacct gttgagaaac cagcgttttt gctctcgtcc cattgcatag gggtacgggc
     9901 attgtcacgt ccaataacac ggatactgtc catgatttct tcaatcggaa cacctttttc
     9961 aagagcctca cgcgcatagt tgagagattc aatatcttct acttgagcca gtgtttcaaa
    10021 cggatagttg gtcatcccaa tctcctcacc ttggtagata taaggagttc ctctcatgag
    10081 atgaagtaag attgcaaagg ctttggcaga tttttcgcgg tattcttggt catttcccca
    10141 gattgagaca atacgaggga ggtcatggtt gttccagaag agggaattcc agccgtcctc
    10201 aactcctaac tctgtctgcc atttgttgaa gatttctttt aacttagcga tattcagctc
    10261 tttttgatag tgccatttag gctgaccttc ctgatactga agaccgatat gttcaaactg
    10321 gaagaccata gacaattctt gcccctttgg atcagagtag agcttggcaa tctctggcgt
    10381 tgctccccaa gtctccccta ctgtcaagaa atccttatct ccaaaggtcg cctgattcat
    10441 ttccttgaga tagggatgga gcataggacc attattgact accttctcgt caggaatttt
    10501 gccaatcatg tcaataacat ccatacggaa accaccaata cctttatcaa tccagaagtt
    10561 catcatctca taaattttct ggcgaagttt ttcattttcc cagttgagat ccggctgttt
    10621 cttgctgaaa aagtggagat agtattgacc tgacttttca tcgtattccc aagcagaccc
    10681 actaaagata gaatctaggt cattgggttc atcgcgccag atatagtagt ctcgctcagg
    10741 gctattagga ttttcacagg cctctacaaa ccaggcatgc tcatccgagg tatgattgac
    10801 caccaagtcc atgatgatac ggatatcacg cttcttagct tctgcaatca gttgatccat
    10861 atcctccatg gttccaaaaa tcgttgcaat cgcttgataa tcagcaatat cgtagccatt
    10921 atcatccata gggctgtcat aaacgggaga aagccaaatt gctgtgattc ctagcttggc
    10981 tagatagtcc aacttactgg taattcctgg caaatcgcca attccatctc cattactatc
    11041 cataaaactc tttggataga cttgatagac tacggcatta tgccaccatt tttcttgcat
    11101 ctgtttacct cattattttc ataatctata gtctatgata gcacttttta aaattttgtg
    11161 caagcgtttg cttaatcttt ttaatttctt ttttagctcc gtagtttcct aacttccaat
    11221 tttttattat aatagagtcc agaggtaaaa aaatgaaaaa acaagctttt agttctgaac
    11281 aatatttgaa tttacaacgc gaccatattt tggagcgcat taaccaattt gacggcaagc
    11341 tctacttaga gtttggcggt aaaatgttag aagatttcca cgctgctcgt gtccttcctg
    11401 gttatgaacc tgacaacaaa atcaagctct tgcaagaatt gaaagagcag gttgaggttg
    11461 tgattgccat taatgctagc aacattgaac attccaaagc acgtggcgac ttaggcattt
    11521 cttatgacca agaagttctt cgtttgattg acaaattcaa tgaattaggg atttttgttg
    11581 gttccgttgt cattacacaa tacgctggcc aacccgctgc agatgccttc cgcaaccaac
    11641 ttgagaaaaa cggaattgat tcttatcttc attatccaat caaaggatat ccgacggata
    11701 tggatcacat catttcccca gaaggcatgg gcaaaaacga ctacatcaaa accagtcgca
    11761 acttgattgt cgtaaccgct cctggacctg gttctggaaa attggcaacg tgtatgtcca
    11821 atatgtatca cgaccaaatc aatggcatca aatctggcta cgctaaattt gaaaccttcc
    11881 ctgtttggaa tcttcccctt catcatccag ttaacttggc ttatgaagct gccacagctg
    11941 accttgatga tgtcaacatg attgacccct tccatcttca aacctatgga gaaaccactg
    12001 tcaactacaa ccgtgatatc gaaatcttcc cagtgctcaa gcgcatgttg gaacgtattc
    12061 tcggaaaatc accatacgct tcaccgacag atatgggtgt caacatggtt ggtttcgcta
    12121 ttacagatga cgaggctgct gtcgaagctt ctaaacaaga aatcatccgc cgttactatc
    12181 aaacagttct tgacttcaaa gctgaaaaag ttggcgaagc tgccgtcaag aaaattgagt
    12241 tgctcatgaa cgacctcggt atcacacctg cagaccgtaa ggttgctgtc gttgcgcgcc
    12301 aaaaagcaga agaaactggt ggaccagccc tagcctttga attgccaaat ggggaaatcg
    12361 tcactggtaa gaactcagaa ctctttgggc ctacagccgc tgccttgatc aacgccatca
    12421 aaaaatcagc tgacatcgct aaagaagtaa aattaatcga gccggaagtt gttaagccaa
    12481 tccaaggtct taaaatcgat catctcggta gccgcaatcc acgccttcat tcaaatgaaa
    12541 tcctgattgc acttgctatc acagctacag aaaatcctga tgctgcccgc gctatggaag
    12601 aactcggcaa cctcaaagga agcgaagccc actcaaccat catcttgact gatgaagaca
    12661 agaatgtcct tcgtaaactg ggtatcaacg taacctttga cccatactac caatacgacc
    12721 gcttatatcg taagtaaaga tttcaacctc tccagcctcg gagaggtttt ctctctgtct
    12781 caggagcaac ctttatgata taatgagaga agaaaactga aaggatttac catgtcaaaa
    12841 gaagttattg tcgaaagttt tgaacttgac cacaccattg tcaaagcacc ctatgttcgc
    12901 ttgattgggg aagaaacagg accaaaagga gacatcatct ccaattatga tattcgcttg
    12961 gtgcaaccaa acgaagactc catccctacc gccggccttc acactatcga gcacctctta
    13021 gccaaactca tccgtacccg cattgacggc atgattgact gttcgccatt tggttgccgc
    13081 acaggcttcc acatgattat gtggggacgt cacaccagtg ctaaaattgc agctgttatc
    13141 aaggattcgc tcaaggaaat cgctgaaact actacttggg aagatgtccc agggacaacc
    13201 atcgaatctt gcggaaacta caaggaccac agcctcttct ctgctaaaga atgggcaaaa
    13261 ctcatcttgg aacaagggat ttcagatgat gcctttgaac gtcatgtgat ttaaaatcga
    13321 gtaggggata atctctagcc cctctcacac caccgtacgt gccgttcggc atacggcggt
    13381 tcaactaact tttaacgcat gtcgttcaag gtaataatcc aaacacgaaa ccagtccacg
    13441 tttttcaagg actggttttg atatagcacg tttaagtacc gacttctgag ctactatagt
    13501 atattgaaac tggaataata cacttctact atacgacatg cctgtcgtac ctaaaaagga
    13561 accagttttt ttcagctggc tccttctttt ttatcctcaa aattctatct taggctttct
    13621 cacgaataac caaaacgcca tcttccatat ctgcttccag atgtttagca tctaaatgat
    13681 ctaagtggaa gtctgtcacc ttatcacgaa tttcttgttc aaccacgcga cggagaggac
    13741 gaacccccat gacttcgtcg taaccttctt ctgtgatata atctttagcc gcttgactaa
    13801 ctaccaagtc aatgtctttc ttagccaagg tttggttaac ttcagccaac atcaaatcta
    13861 caatcttaga aaggtcttcc ttagtcaagt gcgagaactc gatgactgca ttaaagcggt
    13921 tgaggaattc tggacggaag aagggtttca aacggtccat caattctggt ttatccgcat
    13981 cttctgtcaa gttggcttca tagccaaatc cagcatttga ggtcgcaata atgacagtgt
    14041 tcttgaagtt tactgtattt ccttgaccat ctgtcaaacg accatcatct agaacttgga
    14101 ggagaagggt aataacttga ggatcagcct tttcaatttc atccaagaga atgatagagt
    14161 atggattgcg acgaacacgt tctgttaagg tattgctatt gtcatcataa cccacatagc
    14221 ctgctgttgt accaattagc ttagaaacag ctgtacggtc actgtattca gacatatcca
    14281 aacggataat cgcatcctgg gttccaaaca tatcgagtgc caattgctta gcaagctccg
    14341 tcttaccaac cccagtagac cctacaaaga ggaagctgcc gattgggcga tttccttcat
    14401 caaaaccagc acggttacga cggatagcac gagctacagc ttctacggcc ttatcttgac
    14461 caatcacctt gtcttgcaag cgatgggcca tatctttcaa acgttcgata tctgaagctc
    14521 ccatttgcga tactgggata cctgtcattc gttccacaga ttcagccaca tcgttgacac
    14581 ttgcagtcac tttcatatct tctgtgtggt tttcgatttt cttttccaat tctgcaatgc
    14641 gtgttttata gtttagagct gcttcaaaat cttctgcttc aactgctttt tcttgcttgt
    14701 ctttttccgt ttcgatttct cgttcaacag catgcacatc tgttactgga tgttgagccg
    14761 ccaagtgagc agccgttaca tcgacaaggt caatagcctt atctggcaag ctacgttgag
    14821 gaatgtattg aacagaataa tccaccgctg ctttcaagac ttcgtctggc aagatgacat
    14881 tgtggtgttg ttgatagagg tcacgaattc cttgaagaat tttaaaagta ttctctgccg
    14941 aaggagcatt gaccttcact tcgttgaaac gacgagcaag agcagcattc ttcaagatgg
    15001 tgttacggta ttcgtcttga gttgttgccc caatcactgt caattctcca cgagagagag
    15061 ctggcttgag aatatccgca agtcctttag aaccactgtc tccaccagtg ctaccagcac
    15121 caagaatttg gtgaatttca tcaaagaaga ggataatatt ccctgcttct ttcacttcat
    15181 tgactaagtt ttggacattt tcttcaaagc taccacggta ttgagtacca gcctcaagac
    15241 ctgagatatc aatagaaata atttccttgt tcttgatagc agcaggaaca tctccgttca
    15301 caatggcttg cgctagacct tcgacaactg ctgtcttacc aacacctgca tctccgacca
    15361 aaacaggatt gttcttggtg cggcgtgaga ggatttcaga tgtttcttga atttccttgt
    15421 ttcgtccgat aacaggatcc aacttgccct cacgcgcttc tgctgttaag tttcgaccta
    15481 gttttgcaag gacaccgtct tgtttcatac ctgatgcctg ttgtggcatt tgcacatcag
    15541 tttctgcatt tcctggtaat tgaccagtcg cacgatagtg agcaaattcc tcaggtgtga
    15601 cttcgcgtcc attaattaag taacggcgat tttcagaact gtatcctcgc ataccaccca
    15661 tcaattggtt aaataaatca tccatgttat taaaattatt aaagttgtta ttcatattct
    15721 ttacctcttt ttgtttactt agttatgatt actgatattg actatctttg accattgttt
    15781 taaaaaattt agactagcta gatcgctacc ctacgtacta tttctggttt ttctttttca
    15841 agcaggagta gactatcttt acttctgaag atttctagat gaaacataga cccacctctt
    15901 tctattttac tttaaataag tgttctagta aggctttcat ttaccttacg ttcataatat
    15961 actacattgg tcagaaaagg tcaagagttt tgactttaac tgaccaatat ttttttacac
    16021 tcttcgaaaa cctcttcaaa ccacatcagc ttctccttat ctacaacctc aaaaccgtgt
    16081 tttgagctga cttcgtcagt tctatcaacc atctcaaaac tgtatattaa aacgaaataa
    16141 gaacaggaca aatcaatcag gacagtcaaa tcgatttcta acaatatttt agaagtagat
    16201 gtgtactatt ctagtttcaa tctactatat tttgagcagc ctaaagttag ctttctagtt
    16261 tgttctttga ttttcattgt gtatttaaac acaaaaacac cctgaaacat cagggtgcca
    16321 ttcttacatc aaatataaaa ttgcgagggt caggagactt gctagaagtc ccactcccca
    16381 aaagaagaag tcaaccttcc actcgctcca aggatttcct ttaccagaca atcccccaag
    16441 ctcaaaatgg tgatgtacag gcgtcatacg gaaaatacgt ttaccacctg tcagtttgaa
    16501 ataactgact tgcatcataa cagaagttgt ttcaaaaaca tacacaattc cgataatcaa
    16561 gagagtccat tcttggtgga gagccataga gatagctgcc agcatcccac ctagggccaa
    16621 acttcccaca tcacccataa agaccttagc aggcttatgg ttaaagacga agaaaccaag
    16681 cagaccacca atcatggcaa gaatcactag aaggatatcc atctgacctt gcacataggc
    16741 aataactcca taggcagaca aactaatcac aacagaaata ctagccagac catcaattcc
    16801 gtctgtcaag ttgactgcat ttgaaaaacc gactagccag aaaagggcaa aaagaatata
    16861 gaaaatccct agatgcactt ggtaaccaaa gactgaaagc atatcgccac cacgctcata
    16921 gaaaaggtag aaaacgaccc cacctaaaag ctgaagagcc aatttttgct taggattcag
    16981 cccctcattg attttacgaa agaccttgag aaagtcatct aaaaatccga caagtccata
    17041 aaggaccaag atgaacaaaa tcattcctac attattgctg aattggctac taaatagggc
    17101 aaaaaagaag gcaaccaaaa cagaagcaat taagaaaacc aaacctccca ttgtaggagt
    17161 cccagctttt gcctgatgct gtttgacatc ctcatgcatc tgctggcctg taatttgcgc
    17221 ctttctataa aatttgataa aggccggaat tcctactaaa gttagtaaaa atgtcacaat
    17281 tccagcactg atggaaataa acatattagt ctcctaaagt taatgtaatt tttttaatgt
    17341 ccttgattgc tgtattagca cgaacatctt gcttctgaac agtagagccc gaaccttcaa
    17401 atacaagttc tatatttaac cacttagaaa aagcttctgc ggttgctttt gtccaaccat
    17461 acatatctgg aacttcctct gctttatcag ataagagaag aacttgctgg ttaggagcaa
    17521 gattgcttcc ttcttctaca gatgattctt taatctttgt tcctgttcct acaacgattg
    17581 gttgcacaat attgcgacgt aaggcttccg ccaaatcacc gggtgaaata tccttgatgc
    17641 taggcatggc ataagcgctt tgattggtta cctgatctaa cgttttagcg gtagattgga
    17701 ggttaaggga atctttcatg gccactgctc tttccaagat aggattggca aattctccca
    17761 actggatacc tgaataatgt tcaggttgtt ggaccgtcac atacaagata aaatcaggat
    17821 tttcggcagg gttcatagcc acaactgaga aaatgttgtt ggtagaacca accaagtagc
    17881 ctccattttt ctcgtcagcg atttcggctg taccagactt gagggctaca ttttgacctg
    17941 gaacattgac agttgctttt cctgtactat gattatacat agttccatat ctaggatccg
    18001 ttcctactaa gaccatatga gtccgagttt gacttgccgc atccttagaa acaggattcc
    18061 ctacaatttc tttttgagat ttacgaacag attggttatt tgggtcatac aaggccgtaa
    18121 taaatttagg ctccaacatg acgccatcat tggcaatggc tgtaaaggca cgaatcattt
    18181 gtgtttgagt tactgaaatc ccttgtccaa atgaactctg agcgatattg acaatattgt
    18241 cagctggaag ttgacctgca tattcatccg tcaagccaaa acgagtcgga ataccaaatt
    18301 taaagcgatt gagataatca agccaggtag catctcccat cttttgctca agaagcgtca
    18361 tcccaacgtt acttgagtgc gcgaaacctt gagaaaaggt catcattcct ccgccagtta
    18421 atccttcatt gacgtcccaa tctcggatag tagcatctgc tacttttaac tcactactat
    18481 tgaaaacttc tcctcctggg aaagtgttat tatcaatagc agcagcgaga gtcatgacct
    18541 tcatggttga ccctggttca tagttacttt gatagaggat atcacgccaa acaaagtcct
    18601 tagtcagccc ctccttagta tcagcatcga aggtcggccg ttgcgttgtt gcaagaattt
    18661 cccctgtttt agcactgacc aaggtagccg tcatatactt gccttttact ttttcttgaa
    18721 aggcattcat ctgggtctcc atgaaggact gaagggtgct ggaaatagtt gtataaacat
    18781 ccttgccatc taccgtttgt tgggaaactt gttccgttcc ggggacaata ttacccagac
    18841 gatctttttc ataggtaata ataccgtctt tccctgcaag aatactgttc aaggaactct
    18901 ccatcccaga agttcccagc aaactcttgc tcccatcttc attttcatgg agctgagcta
    18961 gtccgataaa actagaagca aattgtccgt ttgggtaact acgattggga ctggttgtaa
    19021 aatcaatccc cttgacctct gcagtttcca actctttttt gatagccatc atattggcat
    19081 aggtaatccc attgcccttc gaaccaaagg aaacttgctt gagattaggt tgcgagagtt
    19141 gctctcttac ataggattct tccatgtcca gatacttatg aaagacctct gcaaccttgt
    19201 taaattgtgt tttttctacg taaagaatct tacccgttgc tgacttatag ttctcatcaa
    19261 tgaccgcata gacattataa gatgtcgcat cctcagcaat cgggactcca tttcggtcat
    19321 aaatagtccc acgtttggca ggaactgtac gggtggtttg atgaaccttc ttagcttcct
    19381 tcgctaaatc cgttccaaag cgagtgcccg tcccaataat gaccgcaaaa ttgactaaaa
    19441 aaacggcaaa aacaaagaca gataataaac tcagactttt tccaactctg cgtctgtttt
    19501 cagccggcga tttccgattt ttggtcgcat aacggattac tttttttgtc cacttcatat
    19561 cttactccgc tattcgaata ttttcattgt ttaattgcaa atcgtgtgaa ttggcaattt
    19621 ctttcaaacg ttctgcacgt aatagttcat tgacctcttg cttggcatcg tccaattcgg
    19681 tcttcttttc ttctatctgc gcattgattt ttgtcaaatc attctgcact tgcaagagct
    19741 tggtctgcat aaaaataata ctaatggcta caataagagt ggttacagca atggaaaagt
    19801 aaaaagcttt ttccacacgc gaaaaccgtt taagttgcat ctgtagtatt tgacctgttt
    19861 tttccattct ttctgccatc ttttttcctc ttacttgtga atttttctgg ccacgcgcaa
    19921 cttggctgag tgcgagcggt tattggcttc taattcttct gcacttggca agattggctt
    19981 acgggacacc aattccatct taggcttgag atcatctggg atgaaaggca aacctttggg
    20041 aacttcaacc gttgaagctt ccttgaacaa ttgcttggtc aagcggtctt ccaaggaatg
    20101 aaaggtaatc actgaaattc taccatccag agccaacatc tccatagcct gctggatgga
    20161 ctcatctgcc gctcccagtt catcattgac ttcaattcga atagcctgga aaatctgctt
    20221 ggcaggatga cccttcttct taagttcctt ggcaggtttg gccgacttga taatttctgc
    20281 caattcagtc gtagtctcga taggtttgac ttctcgagct tgctcaatct tacgcgcaat
    20341 ctgtttagag aatttgtcct ctccatactt gaagaaaata cgaatcaagt catgatagtc
    20401 atagtggttc accacttcat aggctgttag actagcttcc tgattcatgc gcatgtccag
    20461 tggcgcatcc ttcttataag aaaaacctct ctcacgctgg tccaattgag gactagacac
    20521 tcccaagtca taacaaatgc catcaatttc ctgaacacca gcttcgcgca aacgtgcctg
    20581 caaatgacgg aagttatcct tgataaaagt caccattccc ttttcaatgt agggtgccaa
    20641 gcgttgttgc gcattgtcaa tggcattctg atcctggtca aaggcataga gatggccttt
    20701 ttcacttaat ttacttaata aatactcgct atggcctgct ccacccaaag tcgcatcaac
    20761 gtagataccg tcaggcttta cgtcgagcat atcaatcgtt tcgtggagta agaccgttac
    20821 atgatgaaat tcttttgtca tatcttatct attttaccac aaatctgacc agcttgcact
    20881 agtcagacaa atcagacaag agcgctaata tttcttcaaa aaatatgtca aaaatacttg
    20941 acactttatg tttaaaagaa tataatatag tcaaatatat acgacacact tcagaaagga
    21001 gaccagatga atcgtgtgaa agaatttcgc aaggaattgg gtatttccca gctcgaactc
    21061 gccaaggata tcggtgtctc gagacagacc atcaatatga ttgaaaacga caagtacaat
    21121 ccaactctgg aactctgtct caatctcgcc cgcagcctcc aaactgacct caacagtctc
    21181 ttttgggagg aagattttta aaaaaggagc aaacttatga aaaaagaaac ctttactgaa
    21241 aaactgatca aacgcacata cggtatttct ggtccccttg acgaatacaa acggcgtgag
    21301 gccgatagta ttgggaacca agtctttatc gtcctctttt atctgatgat tttcggaaat
    21361 cttattccac tccttctggc ctataaatac cctcaagaag tggctctaat ctatcctcct
    21421 ctgattttag tgattgccct catcgctgct ggctatgtca cctaccaaat gaaaaaagca
    21481 gggattacag ctattgatcc agatatgctg agtgagaaag aaagtaagca actacattac
    21541 ccaggtctga aagcaggttt gttctttggt ctatggatgt tttttataac tcctcttctc
    21601 ggtatactca taggtgaagg tcaggactat tttcattctc ttctcactat aagaaatggt
    21661 gtatcaagca ttctcggttc tatcttcttc ggagcgagca tacagttcct catctcccgt
    21721 cgcattgcaa aaactaagaa agatccggat gaggattagg aggaaactat gaaaaaagaa
    21781 aagaaacagt tacgttatcc tggtctgaaa gcaggttcga tttatggaac aataatattt
    21841 tttataattc cacccattga taccctaaca agtgaaaatc caaattttat cagttctctt
    21901 ctaaatacaa aacatatttt taaaactata ctgggagctt tctttttcgg agtgatgata
    21961 catattgtcg actcacttcg tattgcaaga gctaaaaaag accaggatta ggaggtacct
    22021 tatgaaatca ctagctagac tactgatcat tcatgttttt atcagtattt tccttttctt
    22081 tgcccttatt tcaggagctg tttctcatac agttttacta ctcctactcc tctttcttcc
    22141 tgcgctcaat aaaggacttg agaaaataca atcaaaacgg atacctgtcc tcaacgcagc
    22201 cctcttcttt ctcctcatat cctttccaca acttttaacc aaccctgtcc aatggaaatt
    22261 ttcaatattc ctagtcgtaa ccatcatttc aagtttggcc tacttctata acttttatca
    22321 agtagttaaa gaagtagatc aaaaacagtt gatttaggag cttgctccca taatttctca
    22381 tttcataggc aaataatccc acctagcttg ttctaggtgg gattatttta tttcttaaca
    22441 gaaattgcaa gtcattttcc ttcattttag aaagtcgact ctttccaatt cacactacaa
    22501 tccaagactt gttgcctttc ttcttgattg cggccttcaa tctgatcaat caaaatcttt
    22561 gtagcctgtt gtccttcctc aaaggagggc tgaaccagcg tcgaaacact tggagaagaa
    22621 aagcaagtcc actccgtatt gtcaaaacca atcaacccaa cttgcggcaa gttataattc
    22681 aactctttga taacggtaaa gactagaggt agggcccaac agttagggat aaataccaga
    22741 gttttttcat cgggatcgat ttctttttgt aaaaattctt taatttgttc caaattcgta
    22801 tgcttatctt caatggttag actggcgtga cgcatattag catctgttaa agcatccaca
    22861 aaaccacttg cccgctcaat ccgagtactc aaacgactcg tatccgctgt aatcaagaga
    22921 aaatgctcat aacctttttc gatacaggac tgggtcatgt cataaacggc atcatagtta
    22981 ttggttttaa cccagctagt ccggtgttca tagagctgac tatcaaaaaa gaccattttc
    23041 ttctttttct catcgatgat acgagaatat tttcggaaat tagaggtcgg ctgaataata
    23101 aagccgtcta ctcccaagag aagcatgctt tcaatatacc ggtcctcact ctcttggctg
    23161 taattactat ttcctatcat tacctggtag ccattctggc tggcgatatc ctcaattccc
    23221 ttaacaattt ggtttgagaa actgttggta atatcaccga tcaaaacacc gattaatttt
    23281 gttcgtttgg agtttaagct acgcgcaaca atgctcggtt tgtaatttgt ttcatgaata
    23341 actttttcaa tcttttcacg tgtctcttgg gacatttttt catatttccc gtttaggtaa
    23401 aatgacacgg ttgttttcga ggtctgagcc atttccgcaa tgtcttttat ggtcagtttc
    23461 ttctccaatc taaaacacct cctactaata cttattataa catattcact attcaaaatg
    23521 cctatttcta gcactgcaag cgaatcattc tctcatttat tttatcatat actagacatt
    23581 ttccacgcat ttttgttccg tcaacgaggc acaatttttc acctacacaa atatcctcgc
    23641 ttaataacag aatcagcttg tctgtttcgt catttttcac ttcaaaagcc agagcatttt
    23701 ccacttcacg atcatctgtc tggtagacag aatgacggat gatttcaaaa ctctcatgcg
    23761 caatgatggt ataatccagc atctgattct caaagaattg gcgcttggtg agtttgttac
    23821 ttctttcaag ctcattgtat ttaggagaaa tgatggtatc ttccaaatca aaatcaactt
    23881 cactccatag tctcaactga ttgattttcc catcttgata ggtcacatcc ttgtcaagga
    23941 taaactgagt caacgcctca tgctgacctt gacacctgat gtcatctacc aagagccaga
    24001 catcctctac caacatgagg atttttctct tgtgaagata aggcaaatca ggttctgctg
    24061 accaataagc cccttcaata taatgcactc cctccctttc tttatggtga caaaacaggg
    24121 agtgaggata gtattcatat tcccaggatc ccgtgattct ttccggagct ttcccatcta
    24181 caatgcaggt cgaatgactc caagcactct ttaagagata acgttcatat atctcccgat
    24241 aagaataacg cccagcatct atgaaaatag gttggccttg atactgtaag caaaaactat
    24301 tctcgtcact atggctatgg gcacttccta gcggaccatt tttgaaaaat agataacgat
    24361 gttcatcctt aatgcagaca tgtccagagt cttcaaagat catggaccta ggctgccaag
    24421 ctctcttttc aaattcctgc agtcgcttga ccttttctcg ccccaggaac aagaggctaa
    24481 gcaaatcgac tttaacatcc agaccgttaa gaaggtcttc cttgttcaaa accacagcag
    24541 acaggctcaa catttctgtc gtttctgtag aatcgctatc accaaaagcc aaagttcgtc
    24601 catctaagcc tgtcatcatt tgaatatagg tcgccatctt ttccagcaac tcttggtaac
    24661 tatcttgcaa gtctggaagc aagagacaca aatccagcaa ggctttataa acctctacat
    24721 gatagagaat cgactgttca aactggcttc catctcctaa aatctgtgtc tcaatttgct
    24781 gtttcaactc ctctgaagca aaatggtaag cttcttctag gtccatctta tctgcaaaga
    24841 aatgatagat agcaagcatc ggaattgttt gtaaaattcc ccagttacta agggtgtact
    24901 tggcgcgata gtggcttttc ataaagtcaa tctgcttttc tagactgacc aaaattttct
    24961 ctagttcttt ctcctctagc aagtcaaatt tcaagaggag caagagtagt ttcaaccaag
    25021 taaaggaacg aatacccgta tccaaggttc tagtcatcaa ggagtgagga gaaaattctc
    25081 tcacctgctc aatccaatca aatagaaaga acttgcactt ttgaatatag tccttatctc
    25141 cttctaccac ataccctatc ataaactgca agagatattc ttgtcgattg agcatataag
    25201 cccattctgg atcatcttca aatacttgat cccataccat cggttggatt tgatggattt
    25261 ttgaacaagg ctccatatcc caaggactat caaacataaa acgattgtcc atcaagcgtt
    25321 caagggaact cttgactttc tcatagtctt ttgaacagtg cgacaagata taatcacgac
    25381 attggtttcc atcgattctt tcaaaaaatt gtcttctttc ttctttcatt atctattacc
    25441 agaaaaagaa ctacttaaaa agcagttctt ttgtctttcc cattacactt tccttttcta
    25501 catggatgac cacacctttt gcaatctgca aggagaccaa gtcatcttgg atagaaatga
    25561 tttttccatg aattccagac aataacaaca cttcatcacc agatgttaaa gaagctaaat
    25621 actcttgtcg ttgctccatc tgtttgcgaa gcaacttttg ctgacgaata gaatgaaagc
    25681 ttgacagtaa aaggggactc actgccaaga caatcactat tccataaaac aatgttgtat
    25741 ccattaagct ataatcttaa gccagcttcc gataattccg atgataactg ttaaaataac
    25801 gagtttatat gttgtccatt tcttttcttt gatcaagtag taaactaaaa gtgtaaatag
    25861 ggctggtaga agagctggag caaccttatc aagcattccc tgaatactta cgatactttg
    25921 tttagcgtct gctttaactt cccctgcagc aaaggtaatc ggcaccataa tcttaacaga
    25981 tgtcgctgcc aaaccagcaa ttacggttac accgataata ttggcaatac gagaaatcgt
    26041 tgccatctgt tcgcttagtt tatcaatcac agttgttcct agtttgtatc catacagacc
    26101 agttgacaat ttaatcgctg ttaaaatcgt attcatcgca aggaagaaca agattggacc
    26161 gacaaccaag ccttcttgag caaacgaagc tgcgatggtt gagaacaatg gagctaaaca
    26221 gaattgagag agagaatccc caatacctgc taatggtccc atcaaggcca tcttgatgct
    26281 acgtgtttct tttgttggtc ggccattttc caacattaca aggtgcaagc tggtaataaa
    26341 aggcaggaag tgtggattgg tattatagaa ttcacagttt tcttccaagg cttggtagaa
    26401 accttcctga tcctctccat agtgtttttt caaagcagga tacatcacat tggcatatcc
    26461 caacccttga tagttactat agttaaatcc attttgacaa aagaatgccc gcaaagacgt
    26521 tttaagataa tcacgttttg ttaatttgtt agatccagtc atcgtgtgct tcctcctcta
    26581 ccacatgatc cgctgttttt ggcttgttat aaaattcaat caaagcaaag atagtaccta
    26641 caattgcaat accaattgtt gggatgttta gataagctgc acaaacatat cccaacaaga
    26701 caaagggaat caactctttc ttagccatca ctgacaagat catcgcaaaa ccgatagctg
    26761 ggagcatttt accagcaact gtcaaacctg taagcaatac cggtggaatg tagtctacga
    26821 gtttcaacaa ggtatccatt gaaagggcgc ccaagcaacc caaggtaaat ccaataaaga
    26881 caaacaacca aattgttgca tttagagtga acttgaattt cttcaaatta tggtttttca
    26941 agtgcttcat cgccgtttca ggcgcaccag cacgtacagt gtaggcgaaa gtttgtaaga
    27001 attgaatcgc cacagcaatc ggagtagaga gggcaagagc cgcttctgga ctgactttac
    27061 cagcactagt gatagccatc aaggtaccaa agataccagg tccgattggg tttggtggaa
    27121 cagtacctcc agcaccaaca ccgaatccca tataagccaa ttcaccaata gctcccattg
    27181 caagagcagt aggcagatca cctagaataa ttccgacacc aaatgacaga acaatacatc
    27241 tattggtgta aattcctaac agcattccac taaaacagaa agctgtccat aatccaatta
    27301 aaatcgcttg aaatacatta atcgacataa cgatctcctc ttttaaatat agtccataat
    27361 gttgacttga acagctccat catttcctgt tggagttgtt ttcgtattaa atgttacttg
    27421 atgagtttgg ctcaattcct tgagggccac cttgtcctct tcacccagga agatggagcg
    27481 tgtcacttgc tctttaccag tagcattgtg aatgttccca atattgattt ctttgatagg
    27541 gacaccacct tctaccaagg ttaaagcatc cttcacattc tttacaacga taaagatcgt
    27601 ttgagcagga ttagccttgt gaatgatatc aatcaccttt tgcaaaggga agaaacgcat
    27661 ggcaactgag tctggcacaa ctgttttcat cagagtttgt tgcatcttgt ccgtgcttac
    27721 ttcgtcattg gcaacaatga ccgtattaca acctaggtat tttacccaaa gttgtccttg
    27781 tccatgaatc aaccgttcat cgatacgggt cataacaata tttggcattg tcatatttct
    27841 cctcctacca atataggttc cagtctttgt agaaacggat aagggcttct aggtaatagt
    27901 agtcacccca gatattgcct tcatccactc ctttacctga atgccatgag tacacaccgt
    27961 ggaggagact tgtcccacca ggggtaaatt gatcatttgc ataatgttcg atcaaggaac
    28021 gaagcatggc atgcatagca tgtttataaa tatctttgtc agcatccacc tctgggagat
    28081 gttttagcat ttcatgaatc ccacagacgg cgatagctgt tgctgaagaa tctcgtgatt
    28141 gagcactacc atcattaaaa atcaaatccc aataggacac atgatctttt ggcagacgat
    28201 tcaagaaata attggtcaca cccttaaaca agtcaaagca ggactcgtct tttaagtgac
    28261 gataagtcaa aggaatacca tagactcccc atgattgacc acgtgcccag catgaatcat
    28321 cactataccc ttgtctcgtt acacctttaa agggttgacc tgtctcagga tcaaaataga
    28381 aggtgtggaa ggacgaagcg tcatcacgga ttacattatt agctgaagca tagaaatgac
    28441 tttctgcaat atcgtagtat ttttgatcgc ctgtttcttg ataagcaaag aataagagtt
    28501 ggatattgag caagcagtcg ataatcaaac ggtaatgctc tttcttgccc aagtctcccc
    28561 aagcttgaat aaaaccacct ttttcttgat agcgttcaat caacttatct gcagctttca
    28621 aggttgcttc tctagcctct ccatctccat ttatcttata ttcagccata caagacggtg
    28681 tgtacaagaa gccgagatca tggtgatcca attctactct cttattgaca cgatccagga
    28741 aagaaagaac atttttatga gcgatgtttt taaatgcatc ctgttgactg tattcataag
    28801 ccaaccacag ttctcctgtc cagaaaccat tggtccattc cgtgttatcc atgattggat
    28861 agacattatc aaaggtagct ggtgtcggga aatcttcctt gaaatagtca aggttgagtt
    28921 ctaactgccg aataacctta tcgattgcct ggccgacttc ttctttcgtc agaagtggta
    28981 cttctaagaa gcgctcaggc gattttattt tttcaatcgt aacctttttt atcattcttt
    29041 taccctttaa atacccgatt cgaaatcttc ttcctcttcc tctgcatccg ttgaaaacaa
    29101 ttctttacca tttacgactc cgccctgggc caccactact gatttattaa caacctcatc
    29161 aaagctatga gccattctag caaagactgc ttccattaac atggctaagt tcaaacccga
    29221 gagaacattc attgttttgg ctggattttc tcccattatg gtagaagaaa ccttgaatgg
    29281 cgatcctccc aagagatcac ttaggattaa aacttcttct tcatttgaaa ttgcaagtaa
    29341 gattttttgc ttgagttcat ctgctgacat tccttccaca aagtcaatcg cctccacatt
    29401 ttcttgatta cctgcaatca attgtaaaga actataaatc cctgtagcaa aatgtccatg
    29461 ccctacaagt acaattttca tcttttctcc tttcttgttt aggtttaccg gtttacttta
    29521 tattccccat tgtaatcctt tatttttatc ttgtcaatag tttttttaaa aaaaatatta
    29581 gcgctttcat tatcttttta atcattttaa tagacagaaa tttcaaaata ttccattttt
    29641 aagggaaata aatcttttta taaataaaaa tatttattta ttgacaaaac cggtttacta
    29701 gaatataatt tgattataga gaagtcttaa caaatttgaa aggaagtatc aaatgacaaa
    29761 tacatcattc tcaattgagc agttttcttt aaaaggaaaa attgctctca tcaccggcgc
    29821 ttcttatgga attggatttg ctattgccaa atcctacgct gaagccggcg ctactattgt
    29881 ctttaacgat atcaatcaag atctggtcaa taaagggatt gaagcttatc gtgaagttgg
    29941 catccaagcc catggatatg tctgtgacgt gacagacgag gacggtatcc aagccatggt
    30001 caagcaaatc gaacaagagg ttggtgtcat tgacatcctc gttaataacg ctggtattat
    30061 ccgccgagtt ccaatgtgcg aaatgagcgc cgctgatttc cgtaaggtca tcgatattga
    30121 cttaaacgca ccatttatcg tttcaaaggc agttattcct tctatgataa agaaagggca
    30181 tggaaagatt atcaatattt gttcgatgat gagcgaactg ggacgtgaaa cagttagcgc
    30241 ttatgctgct gctaaagggg gcttgaaaat gttgacccgc aacattgcgt ctgaatacgg
    30301 tggagccaat atccaatgta acggaattgg accaggttat attgccactc ctcaaacagc
    30361 acctcttcgt gagttgcaag aagatggttc tcgccaccca tttgaccagt tcatcattgc
    30421 aaaaacacct gctgcacgtt ggggaaatcc tgaagatttg atgggccctg ctgtctttct
    30481 cgctagtgat gccagcaatt ttgtcaatgg ccacatccta tatgtagatg gcggtatctt
    30541 agcctacatc ggaaaacaac ctgagtaaaa atagaaagaa gatcttatga aaatcgcatt
    30601 aatcaatgaa aatagtcaag ctagcaagaa tcacattatt tacgatagtc taaaagaagc
    30661 gacagataaa aaagactacc aattatttaa ctatggtatg cgtggagaag aaggagaaag
    30721 tcaattaact tatgtgcaga acggactaat ggctgccatc cttttaaata caaaggcagt
    30781 tgactttgtt gttaccggct gtggtacggg tgtaggggct atgcttgctt taaacagctt
    30841 ccctggtgtt gtctgtggtc tagcagtgga cccaactgac gcttaccttt attctcaaat
    30901 caatggtggt aacgccttgt ctatccctta tgccaaagga tttggctggg gggcagaact
    30961 gaccctcaaa ttgatgtttg aacgcttatt tgctgaagaa atgggcggtg gctacccaag
    31021 agaacgtgta atccctgaac aacgcaacgc tcgtatctta aacgaggtga aacaaatcac
    31081 ccacaatgat ttgatgacca tccttaaaac aatcgaccaa gacttcctca aagacaccat
    31141 ctctggcaaa tacttccaag aatacttctt tgaaaactgc caagatgatg aagtcgctgc
    31201 ttatttgaaa gaagtattag ccaagtaaag ctattctaaa ccagaaagga actaatggat
    31261 gacgaaaata ttactgtttg gcgaaccatt aattcgaatc tcaccattag atgccaccag
    31321 tatcggcgat catgttgcca gttcgactta ttttggcgga tcagaaatta acatcgcttg
    31381 taatttgcaa gccctgggta tctcaacgaa agtctttacc gcactccctg ccaacgagat
    31441 tggagatcgt tttctcacat tcttgaaaca gcaccaaatc gataccagtt caatctgtcg
    31501 gcttggcgat cgaatcggcc tctactattt ggagaacggc tttggttgtc gtcaaagtga
    31561 agttttctac gatcgtaagc atacgagtat cagccagatt cggccaaaca tgctagatat
    31621 ggattctctc tttcagggga ttagccattt tcattttagt ggaatcacca tagctatcgg
    31681 tcaagaggtc cgtgcgatcc ttctcctact cttggaagaa gccaagcgcc gaggaattgt
    31741 cgtttcaatg gatctcaatc tgagaacaaa gatgatttca gccctagaag ccaagtatga
    31801 attttctaag tttgcacgtt ttactgacta ttgcttcggt attgatcctc tcatgattga
    31861 tgaccaaaat ctagagatgt ttccaagaga cagtgctagc ctagaagagg tggaaaatcg
    31921 catgcgactt ttaaaagaaa cctatggttt caaggctatt ttccataccc tccgatctag
    31981 tgatgagcaa gacaaaaatg tctatcaagc ctatgctctg gaagaacgat ttgaagagtc
    32041 tgtccaacta aaaactgcag tctatcaacg aattggtagc ggggatgcct ttatatctgg
    32101 tgccctttac caactactcc atcattcctc cctaaaaact accattgact ttgcagttgc
    32161 gagcgcaact ctcaaatgca ctcttccagg agaccatctc tccacttccg caactagtat
    32221 tgaaaattta ctggcaaatg cacaagatat cattcgttag gagaattaca tgaccaaatc
    32281 agatacgatt attgaactaa aaaaacagaa aattgtcgct gtcattcgag gaaatacaaa
    32341 ggaagaagga ctacaagcct cgattgcttg tatcaagggc ggtatcaaag ctattgaaat
    32401 cgcctatacc aatcagtatg caggacaaat catcaaggaa cttgtagact tgtatcagga
    32461 cgatcagagt gtttgtatcg gtgcaggtac tgtgcttgat gccgtaactg ctagagatgc
    32521 cattctagct ggagcaaatt acgttgtttc tccatctttc catgctgaaa ctgcgaaaat
    32581 gtgcaatctc tacagcacac cgtacattcc aggctgtatt accctcacag agatcacgac
    32641 tgcacttgaa gccggtagtg aaatcatcaa actcttccca ggtagtactc tcagtccagc
    32701 atatatctct gcagtcaagg caccgatccc acaagtttcc gtaatggtaa ccggaggagt
    32761 cggcctaaac aacatccctc aatggttcgc tgctggtgca gatgccgttg gaattggtgg
    32821 cgaactcaat aaactcgctt cccaaggcaa ctttgaccgc atcagcgaga ttgcccaaca
    32881 gtatattaca ctcagataaa atcataacta cccgtctaac gggtggttta tctcagagct
    32941 ataagcccaa atcatcagcc agcgcctaaa gacgctggct ttcacgttgt tcaagcctta
    33001 ttgctcttga ctcgtcactt gcctctttaa gagactttgg tattacttac cactatccct
    33061 aaagggatcc tcatattctt ttacactcaa tttatctagt gctatagtag attgaaactg
    33121 gaatagtata cctctacttc taaaacattg ttaaaaatcg atttgactgt cctgatcgat
    33181 ttcgtcctgt tcttatttca ttttactata tatcatactt tactagttct caaattttca
    33241 tactcgtgaa gaaatcatcc actcgataat ttctttaatc ttgactatat ttcttaattg
    33301 tggcttcatt aagccctact ggacttacat aataaccttc cgcccagaaa ttccgattcc
    33361 caaacttgta cttgagattg gcgtgtttgt caaacatcat gagtgcactt ttgcctttta
    33421 aataccccat aaaacttgaa acacttagcc tcgacggaat actgactaac atgtgtacat
    33481 ggtctggcat taagtgaccc tcgatcattt caacaccttt ataactacac aagcgatgaa
    33541 atatttcgcc taaactactt ctatattgat tatagatgac ttttcgtcta tacttagggg
    33601 tgaacacaat atgatagaac acatccactt tgtgtatgat aaactatgag tcttttgtgc
    33661 catatttttt ctcctttcgc tttacaattg gattgaatac ctttattgta tcgcgtttgg
    33721 agtttttttg gtataacctt cgacgcgcac ctcacggagc gagacggact tatatagtgg
    33781 agtgaaatag gatacgaaca aattgattag gaaaatcaaa tgaatttata gaaatctttt
    33841 agcagttata acgttctatt ctagtttcaa aacgctatag tcacataata atgaagtaaa
    33901 aaaggataag tatcaactta tcctttttta aaagaaaaat ccgaagatat ttggccttct
    33961 tcggattttt tctattttcc acagtttcat gtaattcatc tagatgatga acaaattagt
    34021 tgttctttcc tctacggaat agataaaatg ccccaagtag caagaaccct agacttgcca
    34081 agattgactg accttctcct gtctgaggga gattcttttg atccgaatgg ttcttttcct
    34141 cttcagattt ttccttttct tttgaattct gtacttgtgg ctgagctgct tgctctagct
    34201 ttttaaagac ttcctgatct ggagctgatt cctgggtttc aggattatag taggcaatct
    34261 tatattcatc cccttctttt cgaatggtat agactccacg tttcaaaact tggaattggt
    34321 tggaaatagt agagacagaa tcatcatatt tcacaatgcc ccaaactcct tgtttagcat
    34381 cataaacaga ctgaagggtt tcgttatttt cgatgaggct actttctaac tcttttatca
    34441 tttgattgaa ggtggcacga tccacgttag gaatgagcat atagccataa gaatctccat
    34501 tttgcttatg agcctgacta atcgtaagaa attcattttc aacttccttg tctgactgtc
    34561 cttcattgat acccttccag gctccctttt gcaaagcctt actcatgctg attgaactct
    34621 tcttaaagaa aaagtaacca atattctttt tcgaatcgga cgattctaaa aagacacttt
    34681 gggtttcagg ataatccttt tcttgttctg taagggaggc ttctttatca ttgacataga
    34741 ctttatatgg attacttgat tccagttttc tctggtcgat tgtagttgca gcagtatctg
    34801 ttgaagtgtt ttggatattg cttcctaaaa aggcaatctt atcctttagc ataaaccagc
    34861 tcttatgagc agtcaatgtt tgattccagt tggtgaaatc catggttgct gtcgcattgg
    34921 catcatctag tttgctcgtt ccaacgaaag cagacggtaa aactttacct gtatcgctat
    34981 ccgctctctt agcatccgtc tctgttgtac caggcatctt atatggatta actgttggcc
    35041 agtagccatc gctatagtga ctcaaatcgc cattgtaaag atagaacatc ccatcactcg
    35101 tataccaacc acgtttattt tccttgttca tgtgttcgta attcaaggta cgactggaaa
    35161 agagtgacaa gccaaatcca aaccctttct ctgcattgta catggctgtt ttatccatct
    35221 tgttaaaggc agataggtaa cttggtcttg gaacacttgc gactcctgca tcacttaaca
    35281 aggattgcat caaactgata tccttataag tcttcaaatt cttaaagaca tcataataac
    35341 tatccgattg aacaatggtc ttcacaagac tctgcaaacg ttgtttggtt tctccttcag
    35401 acatatccgc tattcggtga atccctctta gtacttctac tgcggccacg tgcccctcgc
    35461 tatttgcacg actgatcgag cgtccacgac tcatatccat cagttctcca ttcaccagca
    35521 aaggagcaaa cgatttatca atccagtggt acatggtttg cattttatct ttatcgattg
    35581 gactcttggt cttttgaatg actggcaaca gttgagacag gccatcaatc aaaacattcc
    35641 cataagcacc cgtataggca acattggtgt ggtcgatata ggatccatct tgataaaaac
    35701 cttcaccttg gtctaccaac ttgaacactt gctcaatcga gcgaatggta gaagaaattt
    35761 cttgatcatc tttacgcagt aaaccagcta ttacttttac tcttcccata tcaactaagt
    35821 ttccacctag agccttaaat gggttatcag tcgtctttcg gaaatgttcg gggtctggta
    35881 caaatttttc aattacatct gtatattttt taatttcctc atcagagaag tattctttca
    35941 tcagagacaa ggtattgttg atggcacgag gtgtaccgat ctcataatcc caccagttcc
    36001 caacaatgct cttttcacta ttgtagacat gtttatgcag ccattccatg gaatccctga
    36061 ctgttcgaac gacagtttca tcttgataat aacgagaaga aggattggtc acttgcttgg
    36121 ccatctcctc caatttccga taagtggcag tcagatttgc agacgtttta taatttgaaa
    36181 atttttccca caaataggtg cggtccgcct gacttgaaat actggatagg ctatcagcta
    36241 cctttccttc caattcctgg tttaatttgg ccatctgttc atttttagaa tcatagtatt
    36301 gattcccagc gatgatgcca ttccagtcat ccaaacggtc tgtgtatgca tccttaacag
    36361 aggccagaat cttcaaagga atctttttca cttccttgcc atctttactg acaatgacat
    36421 tggttgtccc ttccttaaga ggttctaaaa ttccattttt gactgaagca acgtcaggat
    36481 tttctacctt ataagtatag tccgcaagag aaaaaacatg tttttttcca attggtaaat
    36541 caatcttttc ctcaagctgt ttatctgttt gagaatcctc agaaagctgg tctgctacct
    36601 ctaccagctc aatatcctta aaggaaacag tcccagttcc tgtttcatag aataactcca
    36661 gcttgatttt atcaacatct aaagtcgggc tatagtctgc ttcaatggtc tgccagtcct
    36721 ttgttcctga cgtcgttgca gaattccaca atcgcttgtc cttaccactt tcctcaatga
    36781 tacgaacttt ggcaatcccg attttattat ctgttttaat cttgaaacgc agtttatact
    36841 ttttcttagc ttcaatagga accatacggt gaagcgctgc ccttaatttc tcagggcttg
    36901 agatagtgat agtcccatcc ttagtctcaa tgactcgagt tgaggcatct gcagaactat
    36961 tcttctggtc tacccaagct gaccacccct gagctttgct tcctgtccac ggactgcttc
    37021 cgtcctccgt ctgaccaaaa tcaccatttt caactaaatt ttttgtatcc ctttgctgat
    37081 actgaacttc cttctggctt tgctgaatgg tattcgtagt cgtttcttcc gctccaactg
    37141 tcatataatg gtttaataaa aatcctgata aaacaagtga agacaaactc acaatgagct
    37201 tctttgtttt tgtttgcatg tatacactcc aataaacata ttgtaaaatc aataggaact
    37261 aaatctcaaa ttagagattt atagcaacta agtaaaccgg tttaattaaa ttataccatt
    37321 tttaaagtta tttgtaaacg gtttctatca tattgagggc ttattcttca acaatatctt
    37381 ccatccgact cgacgaaaaa agtaaaaact gttacaatgt agaaaaagaa aagaggccct
    37441 catgacttca ctttatgatt tttccgtttt gaaccaaaac aaccaagcaa ctcccttgga
    37501 tagctatcgt ggcaaagttc tcttgattgt caacactgct actggatgtg gtttaacgcc
    37561 ccagtaccag ggacttcaag aactctatga acgctatcaa gatcagggct tcgaaatatt
    37621 ggatttccct tgcaatcagt ttatgggaca agcacccggc agcgcagagg aaatcaacgc
    37681 cttctgtagc ctacattttc aaaccacctt cccacgtttt gccaagatta aggtcaacgg
    37741 taaggaagca gaccctctct atgtctggtt aaaagaccag aaatctggcc cactaggaaa
    37801 acgaatcgaa tggaatttcg ctaagtttct catcggtcga gatgggcaag tctttgaacg
    37861 cttttcttca aaaacagacc caaaacaaat tgaagaggcg atacaaactc tactataatt
    37921 cacaatctca ctatgattag gtttccttta acctgatgaa tagtgagatt ttttgattgg
    37981 ctttgactta aatagaaaaa caccccatga tatgaaacat gaagtgttgt aaagtctatg
    38041 ttgtaggtgc ttatttcaca ttttcaatgt gaccaatgat aacaaatacc atacagaatc
    38101 ttcatataca ctaaacaaat gactttctaa ttatttcaat tagttttggc tagtaaatat
    38161 catttccaac aaacgccctc tcaattcctt atcctgatga tgcaagatat tcattaagtc
    38221 atgagagttt ttggcattga tgaattgatt taacaatcta tcttttaatt catatggaag
    38281 agaagctgtc tttagtagtc taaaaacttc gtcatttaaa gatgtccttt tattatcttt
    38341 ccattcaaat ttagctgtat cattcttatt tggcaattca attatagaca cattcgttcc
    38401 tttaaaatga attctatgtt ttctattgct tggaacgata ctagaatctc cttgtaatgc
    38461 taactctacc attcccattt cccaatcgat tgataatctt gttttatatc tttgaccatt
    38521 ttgatcttca agcatttcaa aagaatgttg tttccctggg aatacatacc aatctacaac
    38581 ctcaggtaaa tcaacaccca tacctatctc agaaccaacc aagggaatga ttgcaccact
    38641 ttttgcaaac acaggcgtag tcgagatgtc cctataaaca cttaacttca caccacctgt
    38701 gtattttttc tctgaaaaga agtcatacca ttcaccttca gggaaccata catctacttt
    38761 tgcagattgg aatgtcaaat ccatcttttc tacaatggga gccaccatca gttctgttcc
    38821 aaaaaagtat tggtttggaa cattatagct ctcatcattc tctggataga aataatagat
    38881 tggactgatt aatggggcac cttcctcatg tgtctttaca ttcatggtat atagataagg
    38941 aatcatctga tgtctcaaac gaaggtattt cttcataatc ttagatgttg tttctgaaaa
    39001 aaaccaaggt tctttactat taaaaggact tctagaacta tgtaatcgag taatcggact
    39061 aaaaacacca aactgtagcc atctagtttg tagctcttcg tcataatccc ccaacatatg
    39121 tccaccgata tcatgactcc accaactata accgatatta gatgctgtcg ctgtaaaata
    39181 gggttgaaat cttaaggaat tccaactaat aatagtatcc cctgaaaaac caacagggta
    39241 gcggtgacta ccaggacctg catatcttga taaaatcaaa ccaccttctg catttttaca
    39301 actatcctga tagtgataat ggtttaaaag ccaaagtgga tctagcatgc cttgtgtccc
    39361 ttgttgccag tcaatccacc aaaaatctac tccctgcttt tctagctcat aatgaacatc
    39421 tttaaagtag gcttccctaa aagagggatt aaaaaaatca aaaatagcag gttcttctag
    39481 ttctacattt aaccccaatc gttttgcgat ttgaggataa gcttcttcat aagcccgtat
    39541 cccatcagca ggatggacat ttaaggagag ttttaacttt ctatcatgaa gttgttgcaa
    39601 taactgttct ggatttggta ttaagtttct attccaacta tatcctgtcc agccacttcc
    39661 aaaacgagct ggaatgtcag ttatatgcca atccatatct aacacaccga tagataatgg
    39721 aattttctct gtttcaaatc tgtctattaa atccaagtat tcatccgacg tataaggcca
    39781 atatctactc caccaattgc ctaaagcata tcttggcaac aagggtgttg aaccagtcaa
    39841 atggtaaaag tctctgattg ctcctctata atcatgccca taggcaaaga aatacaggtc
    39901 aatttgattt tctctctcaa tataaccaga ttgttcatcc caaataaatc cttgagaatc
    39961 atccaataag gctataccat ttcggctaat aattccatct tctaacgaga ttgctccatc
    40021 tgccttatcc agagtccgag ctgttccttt taacgtttca atagattcac caaaatacca
    40081 gcgactacca tatacggcaa aatttccttt taattctata aataaatttt cggcgttaaa
    40141 ttctccttta ttaaagtgca gatgaaaata gtccgtcata atatctagta cgtttgatgt
    40201 ctcgatataa tctaacgaaa tttggccaaa atctctatta tagataagtt gtgtcgttct
    40261 atcctcaaaa tttccagttc gagagtattc taaccttact agcttgtctg ttaatacaga
    40321 gattcgataa aactctccct taaaaatttt caatttgttt tcctcctttt atggtagcat
    40381 aaaaacagaa cgcaccattt ttgatgcgtt tttcattatt ctgaatgcaa tgttctatct
    40441 gttatatcta tgacaaataa tagtcaattg aaaaaatgca gtggacaaaa tatcttttaa
    40501 caaaccaaga gtttattaaa gagttatcac ttttcaactt ttctaagctt atgcagttgt
    40561 gaaacaaact acttttaaac tattaactaa gataggattg ataaataatt tcaaactctt
    40621 actagcaatc atacgatatt caagctcacg tgcttttttc cttcctgctt atttcttaga
    40681 actgaagaac ccggatcggt atataaatta tccggatcaa catagtcata agattcataa
    40741 cagttgcgct tcattaagtc atccccagag caagagcttc atctcgtaat ttttcaacat
    40801 cactaaccgt aggtcgccat ccttcaatca tatttgtact taaagcatac caaacactct
    40861 taaaaacgga tcggttttca aaagctattc ccatgattgt catcttttct ttatctatat
    40921 ctaaggacat atgctacctc ctttagatac attataccat gtttctctgt agcttttaaa
    40981 aattttattt tgtttgtcat atctaagttt tcagcacgct tatcctattt atccgagaat
    41041 aattaaatat ctatctcata aactagcagt agttgttagt aatagaccat atacccaaca
    41101 atttgttctg ccatgagttt ttcatttcac taatttctta aatgcttcta aatgacttgt
    41161 taacacaaat gattcaacat caacaagtac aatttctttt tctatcttga agatatttaa
    41221 atagttccag atattatttc taaacaatt
//
LOCUS       DAVLDI010000014        37462 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLDI010000014 DAVLDI010000000
VERSION     DAVLDI010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37462
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.014"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..1179
                     /locus_tag="VXD01_000720"
     CDS             <1..1179
                     /locus_tag="VXD01_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001161118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601151.1"
                     /translation="GVAGKAGADGRTPYVHFAYSENADGSGLTMTDNGQRYFGHYSDY
                     EKPDSSDKTKYKWADRWAKVDGGYVNIYALSKNRSIGKSYHVSEFNMDVLSGNITLKA
                     IGSDPYIGAVSSHPGIFIKQQGMKIPVIQGRSICITITNPLFRKNYISFFNSLGKTVK
                     TYKHYNTNKFLISSADLVGVEFIALRYGAGSSNIQIGTVLETKVKVEYGTVHSDWSPA
                     PEDIESNINSKADQGLTQEQLNALNEKSQILEAEMKAKASMEAFSELEKAYNAFVKLN
                     ADSQKKSESDLVEAGRRIDLLTTQFGGLAELKTFIDTYMKSTNEGLIIGKNDASSTIK
                     VSSDRISMFSAGKEVMYISQGVINIDNGIFTASIQIGRFRTEQYHLNKDVNVIRYIGG
                     "
     gene            1190..3268
                     /locus_tag="VXD01_000721"
     CDS             1190..3268
                     /locus_tag="VXD01_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="structural protein"
                     /protein_id="HEV0601152.1"
                     /translation="MTKFINSSGSLHLNIYIEQVSQDIANNSSRVSWKATVDRDGAYR
                     TYTYGNISNLSVWLNGSSVHSSHPNFDTSGQEFTLASGEVTIPHSGDGTKTFAVWASF
                     DPNNGVHGNITVSANYTLSSIPRSSSVSDNALSGNRRLGSPHTLTIDRKSSLFTHQVW
                     YRVFGSNWIDLGKNHATGVSFVPNIDLARYNTKAKSGTMDICVRTYNGTTQVGNDVYS
                     NGWYFEIPESVKPTFSGITLTDMNTVARQLLSGNNFLQIISDIQVNFNNPSGAYGSTI
                     TGYRAEIVNKNQVITVNGGRLGMMNFNGSATIRASVVDSRGRQSDTRDITINVIEYFA
                     PAFSFTAFRTREIPNIIQVVRNAKIAPITLSGSQKNVMTLSFKVARLGSTTFTADHGR
                     ASGIWTTQHTLNNSAANMAGNYVATKSFVVIGTLSDKFTSTEFTATVATESVVMSYDK
                     DGRVGIGKVAEQGGAGSLDVLGDIYARNKPIQQYQLTDNNGCGKLIKQDFNTMKETGT
                     WWINGSSQNNPFSGTWGMLEVFRPNPGSHERIQRFTTSTGYMAVRENGYDNNWRPWRY
                     LVQQSKSTNNSDYVALLKSESTPTPWQNAILQNGWNHHRDYGGVQFSKTFDGVVCFKG
                     TCKGGKIARESIILTLPEHFRPSTTLFKTALNNDYGSAVIGIYPNGNVVVKSNVDATW
                     LNFDNVFFKI"
     gene            3328..3591
                     /locus_tag="VXD01_000722"
     CDS             3328..3591
                     /locus_tag="VXD01_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601153.1"
                     /translation="MLKVTKTRQLVTEFFAQDGDQQKLVKTTVINTDNKAVSTISETL
                     HDPELYANNRISMRKHEQELREMRYKIEDAILAELEADAEHKE"
     gene            3601..4017
                     /locus_tag="VXD01_000723"
     CDS             3601..4017
                     /locus_tag="VXD01_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEV0601154.1"
                     /translation="MKIEFFNFLRSVVQTEDGLVLYALTLIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSICLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            4021..4353
                     /locus_tag="VXD01_000724"
     CDS             4021..4353
                     /locus_tag="VXD01_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV0601155.1"
                     /translation="MQQITEIITNGAISILVVLAGVVVRAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            4357..5313
                     /gene="lytA"
                     /locus_tag="VXD01_000725"
     CDS             4357..5313
                     /gene="lytA"
                     /locus_tag="VXD01_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0601156.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIADKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(5619..6761)
                     /locus_tag="VXD01_000726"
     CDS             complement(5619..6761)
                     /locus_tag="VXD01_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0601157.1"
                     /translation="MWMEELPNGKFKYFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKIKQKLGEKQHSVSNITFEKLYEEFEENWKHGVKNSTVYASKNVKKEILKQIE
                     GDYLVRNIDRRLLQKVIDQLLQDGRSHNYVSKIKFKLNQIMKFAIRMNYIDTNEMLFV
                     ETPRKVITSDELRKKNTKYLDQKEFKLFIQNLKDEALCDYRITKYIRIAKVLFLTGMR
                     YGELAALNYKEDIDFSKKTIHIKHTYDFRQKERTTPKTIKSDRVITAPQKVLDIIKEQ
                     IIENATNGFDTDFIFINTLGEPITNARVICALKRHGQKIGIEKNITTHTFRHSHISLL
                     AELGIPLTAIMDRVGHSDSKTTLEIYSHVTQKMVSDISSKLDKVKF"
     gene            complement(6880..7230)
                     /locus_tag="VXD01_000727"
     CDS             complement(6880..7230)
                     /locus_tag="VXD01_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601158.1"
                     /translation="MNIIAIIIIVIFVGGVIGAVIDNQKKSPEQRERELETFRANQEK
                     KKQEKKQNIITCPNCKSKDVTFLQQDKKAFSVGKAVGGAVLTGGVGALAGFAGKKGNK
                     QWHCQNCGNFFETK"
     gene            complement(7244..7624)
                     /locus_tag="VXD01_000728"
     CDS             complement(7244..7624)
                     /locus_tag="VXD01_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV0601159.1"
                     /translation="MTEKEFSQNLGIDIEIFEDGLFPDEAFYIPALKTMFLSDAISDE
                     KRVQVALHEIGHRNHAPDTYQLFREKCELEANRNMIHHLMKAELDIAEDATTFNYLVF
                     MEKYNLKTIADEIMVKEEYLALLN"
     gene            complement(7646..8002)
                     /locus_tag="VXD01_000729"
     CDS             complement(7646..8002)
                     /locus_tag="VXD01_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0601160.1"
                     /translation="MTILDRIRSLANDRKVTLAELERNLNFSNGSLRKWETSTPSGDK
                     IEKIADYFNVSTDYLLGRTDNPTIANKKEQFFFEGKEVDVEELASTAMRFNGKPLTEE
                     DKKAIQNIIEIYLRKQ"
     gene            8278..8463
                     /locus_tag="VXD01_000730"
     CDS             8278..8463
                     /locus_tag="VXD01_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0601161.1"
                     /translation="MIYDKIKEIASEKGISIYRIEKDLDLGNGAISKWNNSSPSATTL
                     NSIANYLNVRLEQLLEE"
     gene            8465..9163
                     /locus_tag="VXD01_000731"
     CDS             8465..9163
                     /locus_tag="VXD01_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEV0601162.1"
                     /translation="MNELINVTLNDNQEPVVSGRQLHEALGVNSRYTTWFDRMKEYGF
                     TEGQDFLPNLGKSTGGRQATDHIIKLDMAKEIAMIQRTERGKQVRQYFIQVEKDFNSP
                     EKIMARALLMADQKVHKLEAQIEADKPKVLFADAVSASHTSILVGELAKLISQNGYKI
                     GANRLFSWMRENGYLIKRKGSDWNMPTQRSMDLKLFEIKETNVQHADGHITVNKTPKV
                     TGKGQQYFIDKFLN"
     gene            9349..9690
                     /locus_tag="VXD01_000732"
     CDS             9349..9690
                     /locus_tag="VXD01_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEV0601163.1"
                     /translation="MMVVLANHPNWQVYPDEIAKRKGVNRKTIDKYFKIFEEAGYLRK
                     IRKKPPGNGGSHIFRFFSDVKISDFQFDIMKQRLNLSIKRASMNYNSDIPKSEMSESE
                     MSESEMSDFGH"
     gene            9847..10113
                     /locus_tag="VXD01_000733"
     CDS             9847..10113
                     /locus_tag="VXD01_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601164.1"
                     /translation="METVQIVRIKDVIIEKISANDEELERIFGCSKRQAGDMRREMKK
                     LPSQQKYLRNDGQLVTIKGFDAYLQYRGSQSWKKEMAKTVKMTR"
     gene            10197..10649
                     /locus_tag="VXD01_000734"
     CDS             10197..10649
                     /locus_tag="VXD01_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601165.1"
                     /translation="MPNWAEGTLKLRGRRENVASALKEMLLGDEGATLEEEYDGTLLR
                     FKNEYDYFYINGTRRAFISSKDIEIWLDDDFVIIELEDFEQAWAALADNYTEISSKFD
                     VDIKIFTFEMGMEFTQEIEISKGEIIKNIVNENFTNYSWDVPFSRLGG"
     gene            10655..11356
                     /locus_tag="VXD01_000735"
     CDS             10655..11356
                     /locus_tag="VXD01_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEV0601166.1"
                     /translation="MADLTFAELQRKMQIEKQTKQGVKYPFRTAEDINNKFKSLDSGW
                     SVSFPEDDIIQKGDKLYYKAVAVAKRESDGTIEKAIGWAREEDVPIFHTQKGDVKQMQ
                     DPQWTGAVGSYARKYALQGLFAIGGEDVDEYPVEESQEQGQNNQQQKPNNQQAQGQNQ
                     VRYIDNIQYQEINDLINDIAKIKGMPFDTLANYVLSEKLKGLQDFHRVQVGDYEVLKN
                     YLTEQLAKAKAKRGN"
     gene            11359..12351
                     /locus_tag="VXD01_000736"
     CDS             11359..12351
                     /locus_tag="VXD01_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEV0601167.1"
                     /translation="MVKDVTNSLTEIKVDFQPAVINVDREAIEAQVAAAIAQYSGREV
                     TVDNYKEVYEERTRFNKLIGGLDTQRKDFNRQINEPAKDFDKWVKEKVIKPIEGVTDA
                     MSAGLNAIDEHERLMRVDVVRATFEDKCMVAGIEKSTFADKYDEYSLKKYFKTGKYEL
                     KKTTLDEMDGLVLSEFDALEEYKANKQAIQEQAQEYDLPADSYIRHLEDGKSLVDILK
                     MMKTDRDAEIARKEQKEAQEKAKAERLEEIAQSAKKNANANIKAYDAETGEILEQGTI
                     TPEPQNNAREVAKFEPSEPLVKLVRLELHGGLEQWENTQEYFEDNFIGFETLED"
     gene            12373..12549
                     /locus_tag="VXD01_000737"
     CDS             12373..12549
                     /locus_tag="VXD01_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601168.1"
                     /translation="MRCFYVSGKIADLDLGSEINAENSFMAAIEFVKRYTGLLKFGSN
                     EIKVSEVEEVQNDK"
     gene            12539..13084
                     /gene="ssb"
                     /locus_tag="VXD01_000738"
     CDS             12539..13084
                     /gene="ssb"
                     /locus_tag="VXD01_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0601169.1"
                     /translation="MINNVVLVGRLTRDAELRYTQSNIAVATFTLAVNRPFKNEAGER
                     EADFINCVIWRQSAENLVNWAKKGSLIGVTGVIQTRSYDNQQGQRVYVTEVVASNFQL
                     LESRNSQQNNQGHQDHHGGYQQQGYSNQGSSFQNGNSYGQQGSFLEGNTTNLVPDFTR
                     DNNPFGRPTNPLDISDDDLPF"
     gene            13110..14249
                     /locus_tag="VXD01_000739"
     CDS             13110..14249
                     /locus_tag="VXD01_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV0601170.1"
                     /translation="MKFLDLFAGIGGFRIGMESAGHECIGFCEIDKFARASYKAIHDT
                     KGEIELHDITTVSDDTIRGIGHVDVICGGFPCQAFSIAGNRRGFEDTRGTLFFEIARF
                     ASILKPRYLFLENVKGLLNHDRGNTFEVILSALDELGYDVEWQVLNSKDFGVPQNRER
                     VFIIGHSRKRGTRRVFPIGRANREFDFEPKIKIVGNTKNPNGTSQGTGSVVYDSNGLV
                     GTLCARDYKEPKQVAIPVLTPDRVNKRQNGRRLKKNGEPMFTLTAQDRHGILIKEATK
                     KGYAEATVGDSVNLSHPNSKTRRGRVGNQIANTLLTGESQGVVEPDFRIRKLTPRECW
                     RLQGFPDWAFDKAQEVNSNSQLYKQAGNSVTVNVISAIAQGLGGN"
     gene            14284..14487
                     /locus_tag="VXD01_000740"
     CDS             14284..14487
                     /locus_tag="VXD01_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601171.1"
                     /translation="MTKIEIVMVLTTLMSITWAAIVTIHTMQAIKKHKAKVDYYQKPQ
                     VQCEIARHVLKNKWYSDGGEVFR"
     gene            14541..14975
                     /locus_tag="VXD01_000741"
     CDS             14541..14975
                     /locus_tag="VXD01_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601172.1"
                     /translation="MDKKLIGLDLTHIADGGLQEKLDKELEKVFDNILDLNTDAKAKR
                     KVTITLTMSANEERTVVDTTMEVKSKFAPQNGVATTILIGRDFDTGQVHANELKSTVP
                     GQMYFDENGEILTDIGQPVAEIEQQAETKPDIIDFNKKKVGN"
     gene            14977..15714
                     /locus_tag="VXD01_000742"
     CDS             14977..15714
                     /locus_tag="VXD01_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601173.1"
                     /translation="MTTENLKAALEYAVELNEHGLEILTAADGTEYYDANKFNLKELD
                     PKRYPKTLELSTLTSLVDYLKTDLNNLKNQRLIVAVEKNDEVCVWSENDELERRTLLV
                     DVKARIPELSFGRFLSSEQFNIMLQSNFIDDNDRGTLLEFASALKIENGAEIEDNGVS
                     QVATVKTGVASLAKGKAPNPVTLRPYRTFSEVEQPASLFVFRIDKQANMALFEADGKR
                     WVADAVGNIAAYLKEQLADQKLITVLA"
     gene            15731..15943
                     /locus_tag="VXD01_000743"
     CDS             15731..15943
                     /locus_tag="VXD01_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601174.1"
                     /translation="MSDYKQRMIEEYKQLKERTNKLSLMISNYYVGTLDFKLKCPIEL
                     LETQHYTMCAYLKILEQRAEIENIEF"
     gene            15954..16355
                     /locus_tag="VXD01_000744"
     CDS             15954..16355
                     /locus_tag="VXD01_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601175.1"
                     /translation="MKFEFSLPRNTKLKSLNMVINSNDRQHQTDKAKVTKRIRAFAYW
                     HTSMNKDKGRAAFSPSNPCEVTVTIYSPTKSKLDPPNLYPTVKAIIDGMTDAGIWTDD
                     NHKVIKKLSFVYGGLSEEKGHYRLEFDIEEV"
     gene            16357..16563
                     /locus_tag="VXD01_000745"
     CDS             16357..16563
                     /locus_tag="VXD01_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601176.1"
                     /translation="MIEVNIKFDNFEAHGFYQDDTKLGKIRDAIISQMNNGHVVILGE
                     DRSILLNPKVIKCVQFEVVEDDQI"
     gene            16613..16927
                     /locus_tag="VXD01_000746"
     CDS             16613..16927
                     /locus_tag="VXD01_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601177.1"
                     /translation="MEELKKKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMAE
                     DGMTFMGAMECIFADEKPTDYDLGATKDWLPKSKEFDDWIGYAPSMAQVVIAVYLIYR
                     GN"
     gene            16929..17429
                     /locus_tag="VXD01_000747"
     CDS             16929..17429
                     /locus_tag="VXD01_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0601178.1"
                     /translation="MNIKALIKKYEELWNEHSPFYEPVPYTSMVELFLKELKQLDEPE
                     KVKVPQFMADWIDYFKKNGDWDLFQAMDYLFGKKEIREWLEYKNNQDLFARAWLDGYE
                     VEKEKRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEDAKFGWVFDCPGI
                     EIEEVK"
     gene            17429..17722
                     /locus_tag="VXD01_000748"
     CDS             17429..17722
                     /locus_tag="VXD01_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601179.1"
                     /translation="MTQTLEEGMKNQSKCIKIPMEIRPFDIGYRIVNQHGNPLALKNG
                     ASIFDLPSLAEKAIKKEFSKDDPDFDIEKHFVEEVAIVNLSKFHSYFEEVIHD"
     gene            17722..18114
                     /locus_tag="VXD01_000749"
     CDS             17722..18114
                     /locus_tag="VXD01_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601180.1"
                     /translation="MTKKKIERLSVIHRREINWLKWYFLRDKKNPKRTILEQKIIVSH
                     IKTDRLEAKFLTNLKKSTEDFIDGSDPKYLRAIKEVYVYENMNVIGACQKILFYSPTQ
                     AYVLLNAWFNDYFRATYTELLENAILDK"
     gene            18180..19274
                     /locus_tag="VXD01_000750"
     CDS             18180..19274
                     /locus_tag="VXD01_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000425577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4417 domain-containing protein"
                     /protein_id="HEV0601181.1"
                     /translation="MEMLQIEYVDIKSIKPYHKNARHNDGEATEKVAASIKAFGFQQP
                     ILVDDNNIIITGHTRLKAALSLGIDTIPIAHAVNLTDEQIKAYRLADNRVAEYSTWDS
                     ELLNIELSQFETIDMAQFGFELSVTGFNFGNEEEQQEETENEEEDAEDFHRDTTINQY
                     NLFNYDDTRVEGFYNMPKIEGVDHIPKDFQGFNYVLNKPDYSSCVHFFLDDYQFERIW
                     QRPDFYIEKLLEFDSALAPDFSLYLDMPIAMQVWNIYRSRLIGQIMQDYGLTVIPTVS
                     WASEESFDFCFDGLPKNSTLAISTIGVKQNKEQFEVWKNGVTEMIKRLTPKRIVVYGG
                     KVEYDYKDIEVVYFENATTERMKESGTKTN"
     gene            19255..20001
                     /locus_tag="VXD01_000751"
     CDS             19255..20001
                     /locus_tag="VXD01_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601182.1"
                     /translation="MAQKLTKLKDIFKHVSSIDLGKEILFEDLELYNKETETSKQYQS
                     IEEAENDLSLMEKVNKINFTLGGGRGANFEKGKDGKYPGFRGAGGARDSGSSKALHPA
                     SLNNQGRFSSVEGAIQGFIKKHGGSRTEYSTAVDSQGFAHNYVHGGKNSVQILPISGG
                     FTAIHNHPNGSNFSSTDLHSFAALKGMNTLVATNSSKAYRITKGANFDAKGFDKAVSK
                     SRFTTKDYNKGADLWLKKNAKKYGYTYSYE"
     gene            20205..20660
                     /locus_tag="VXD01_000752"
     CDS             20205..20660
                     /locus_tag="VXD01_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein"
                     /protein_id="HEV0601183.1"
                     /translation="MPRDGTKNLKPVTERTKDEARAISSKGGKASGIARRKKADLKKA
                     FETLLSLDVTDSKIKKQLEEMGMAGNNEALLAFATFQQAVKGNQKATENIIKLTNTKD
                     KYDIQEQKERIKALKYENRERAEAEKGSSETIEIVDAWAEDVRGATDDL"
     gene            20650..21960
                     /locus_tag="VXD01_000753"
     CDS             20650..21960
                     /locus_tag="VXD01_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV0601184.1"
                     /translation="MTFNVQKNINPHFKSVWISSLPYNVLKGGRNSFKSSVIVLKLAY
                     MMIRYIIAGEAANIVVIRKVANTIRDSVFNKVWWALNLFGIAEQFTKTVSPFKIVHKT
                     TGSTFYFYGQDDFQKLKSNDIGNIIAVWYEEAAEFNDQEDFDQSNVTFMRQKHPRAKF
                     VQFFWSYNPPRNPYSWINEWFESIKTNKNYLAHSSTYLDDELGFVTEQMLEDIERIKE
                     NDYDYYRYLYLGEAVGLGNNVYNMSMFHAIDALPSDDKLIGISFALDGGHQQSATACC
                     AFGITAKGKVILLDTWYYSPAGQVVKKAPSQLSKEIYTYIRSVIEKYRVQALQYTIDS
                     AEGALRNQMFLDFGLKWHPVAKLRKVTMIDSFQSLLAQGRFYYLNTENNKIFIEEHKM
                     YRWDEKTIKSDNPSVIKEDDHTCDTTQYFVLDNAKLLGLRVGNV"
     gene            21973..23541
                     /locus_tag="VXD01_000754"
     CDS             21973..23541
                     /locus_tag="VXD01_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0601185.1"
                     /translation="MSLFQKVKDFFSRGRYYMQTSNLNSILEHPKIAVTQEEYDRIKR
                     NLVYYQSKWDDVQYKNTDGDIKSRPMNHLPIARTASKKIASLVYNEQATITTKNEILQ
                     KFLDDMLTNDRFNKNFERYLESCLALGGLAMRPYIDGDKVRVAFIQAPVFFPLESNTQ
                     DVSSAAILTKTIKSEGRKNVYYTLVEFHEWVTADGQETGSTNDKKYYRITNELYRSDV
                     NDVLGQRVNLSELDKYKNLEPVTVFENLSRPLFTYLKTPGMNNKDINSPLGLSIFDNA
                     KTTIDFINRSYDEFMWEVRMGQRRVIVPEHLTQRQYQRPDGTIDFRPRFDVEQNVYMQ
                     IGGSSMDAGGITDLTSPIRANDYILAISEGLKLFEMQIGVSSGMFTFDGQGMKTATEI
                     VSENSDTYQMRSSIVALVEQSIKELCVSMCELGKAVGVYSGEIPELDDISVNLDDGVF
                     TDRHAELDYWAKMVAAGFSTKKRAIGKTLNISGVEAEKELNAINSELLPMNDAELAIY
                     GMHDQNEEEADDKG"
     gene            23528..23701
                     /locus_tag="VXD01_000755"
     CDS             23528..23701
                     /locus_tag="VXD01_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601186.1"
                     /translation="MTKVKFGVTSVDYSASIEDTPTIKLGLIIRGSGRLDASSVIKKL
                     IKDVSELEYELEE"
     gene            23744..24895
                     /locus_tag="VXD01_000756"
     CDS             23744..24895
                     /locus_tag="VXD01_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000730221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor capsid protein"
                     /protein_id="HEV0601187.1"
                     /translation="MKKKRKQITFNDQQFPLQMQGVGDIYEKLQIDIFDRMIKRLKER
                     GSIDLMRNPYIWQLEKLNDMHMLNEQNLKLISERTGIAERLLRDVIENEGLKVYKDTK
                     QQLEEDLNKIPEGEISNGVTDSLEAYSRQAVSDLNLINTTLPKSLQVAYKSIVEETVA
                     QVVAGTKTSDVALHDTIMKWQKNAFTGFVDKGGRHWKADSYARAIIKSTTYKVYNEMR
                     TRPAEELGVDTFYYSMKAMARPACSPLQGQIVTKGAGRKIDGITIYSLLDYGYGTAAG
                     CLGIHCGHYLTPFIVGVHELPNLPDYLKNLTPEQAEENARIEAGQRGLERLIKTHKER
                     LHYAHTLQDDKMIQAERLKVRGYQTKIRNLINQHDFLTRDYRREKLYIS"
     gene            25034..25597
                     /locus_tag="VXD01_000757"
     CDS             25034..25597
                     /locus_tag="VXD01_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000896122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HEV0601188.1"
                     /translation="MAFTTEELLNLGLTEEQAKSVFALRGKELNEDKSALETIKQERD
                     SLKSQLQKAEEQVEHLKSLENISAEQKDAIDKLQAEYDKYKNEAAAELAQTKKVSAIS
                     LALKDTNAFNPDKLMKFIDVDAIQLDDNGKPQIDEVINGLKESDPYLFKAEESKPSPN
                     ILPQGNPAGEGTSDVDPFQAIIDGYGK"
     gene            25615..26496
                     /locus_tag="VXD01_000758"
     CDS             25615..26496
                     /locus_tag="VXD01_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEV0601189.1"
                     /translation="MPSNQNNAVRRYEKQYAGILETVFRVRAAFSNALASIQILDGVQ
                     ENSKAFSVKTNNTPVVIGEYKTGENDGDFGDNSGAQSRFGGLTEVKYENTDVNYDYTL
                     TIHEGLDRYTVNNDLNAAVADRLKLQSEAQTRTVNKRIGKYLSDNATNTEALADFTDD
                     KVKALFNKLSAFYTNNEVTAPITVYLRSEFYNAIVDMASVTSAKGATISLDENGLPKY
                     KGFTLEETPAQYFETGVIAIFSPNGIVIPFVGISTARVIEAENFDGVKLQAAAKGGTY
                     TLDDNKKAIYKVTGTIV"
     gene            26507..26740
                     /locus_tag="VXD01_000759"
     CDS             26507..26740
                     /locus_tag="VXD01_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001240344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601190.1"
                     /translation="MAIYKATKNLFFEQLNMDVIVNDIIELDEDYAKEVNKKLKNAFP
                     DVKNVLELVDKNGTLEPEDAPSVDDASQATVED"
     gene            26783..27175
                     /locus_tag="VXD01_000760"
     CDS             26783..27175
                     /locus_tag="VXD01_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013794407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601191.1"
                     /translation="MTYLTQEEFDELDFDEVTDFEKLAKRAKIAIDLYTNGIYQKDID
                     FEKEIAYRKSAVKLAMAFQIAYLDASGIMSADDKQLANSVSIGRTSISYSTSQSTLAG
                     QRFNLSMDAENALRQAGFSLVVGVAYDR"
     gene            27165..27536
                     /locus_tag="VXD01_000761"
     CDS             27165..27536
                     /locus_tag="VXD01_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV0601192.1"
                     /translation="MIDKRLLKGIDKRLLKDVLTIKKVADKNDYGDEVYSEPLTIKNV
                     RFDRSVGGSGNRNSKTGTGNSKSRQKQGVIYLYPSLSFVTVDNSWMGAKVNDGIGDYT
                     INGFQTNYYDGEIFSQEIEVI"
     gene            27536..27880
                     /locus_tag="VXD01_000762"
     CDS             27536..27880
                     /locus_tag="VXD01_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV0601193.1"
                     /translation="MNIAIKVDLQKAKQKLSNESMTRGKIAVASKILLDNEQYIPLRG
                     GELRASGRIVGQGDAVVYGTVYARAQFYGANGIVTFRRYTTPGTGKRWDQVATSKHAE
                     EWARAFVKGMGL"
     gene            27880..28287
                     /locus_tag="VXD01_000763"
     CDS             27880..28287
                     /locus_tag="VXD01_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV0601194.1"
                     /translation="MRENDFQNVLLKHIKTLNLPVEPRFDYFEDDKDDLVINQIPGGK
                     VDREYMDGTQEVSLPFEIAVKAKKNSVANDTIWLVTSELAKIDLVLPSDNNSYEYMGM
                     EVSRPAMKGKDEQGYYYYTIEIVAKIVIERNKQ"
     gene            28284..28733
                     /locus_tag="VXD01_000764"
     CDS             28284..28733
                     /locus_tag="VXD01_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0601195.1"
                     /translation="MTRQKNALRGHFVAPYNGGTEPTTEDTWLELAKWISDVSDDTDE
                     KTDDQAYYDGDGVEETTVVSVKGAYTFEGTYDPDDKAQALIAGMKYKTGDDRKLWHKV
                     VSSDKKKQWVGAATATEIKAGSGAASDYEVFGCKLSYNSTPKETGIG"
     gene            28798..29286
                     /locus_tag="VXD01_000765"
     CDS             28798..29286
                     /locus_tag="VXD01_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601196.1"
                     /translation="MTDIQIELKRTGFPVKIGEVELWFDTSQESLMRFYDMEEELKRR
                     LVQYELDVVSANINNKIERDGVTKEVVAGAIELEKKQLEIQYDLIFGDGTFDKLYSVY
                     PDYNALNNALEQTAIMLHDKLEELAEQHKTVVKERASHYLNKGKVTPIKNNKKQKKNK
                     KK"
     gene            29299..29868
                     /locus_tag="VXD01_000766"
     CDS             29299..29868
                     /locus_tag="VXD01_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601197.1"
                     /translation="MSMKLNDALITNFSIADKEYDIDLSFNKVLDVFEILKEDEMTRL
                     EQAQLIVHLLTGQELYDIKEVVDCWIYIKEHFLGIEKETVQYDLLGNPMPKAKGEEEQ
                     EKLIDFEQDAEYIYASFLQAYGINLLKVQNELTWTEFKALLNALPDNTIMQQIIEIRA
                     WKPEYGGDKNKMRKLQAKYSLGKEGEDND"
     gene            29861..33163
                     /locus_tag="VXD01_000767"
     CDS             29861..33163
                     /locus_tag="VXD01_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEV0601198.1"
                     /translation="MTDGKVTIVVDVDGNKVKVLNDELDKTAQKGDRGSDSLKKFAIG
                     GAAFKLASKAVDLLTDSLGGAIQRFDTLESYPRVMQAMGHSTEDVTRSTKKLAAGIEG
                     LPTTLNEVVGTAQRLTSITGDINKSTDLTLALNNAFLASGSSSADASRGLQQFSQMLS
                     AGKVDMQSWKTLQETMPYALQKTAESFGFAGQSAQNDFYSALKEGRITFNQFSSKLVE
                     LNGGVGGFAELAKTNSKGIQTSFGNLKNAVVKGVANTIKALDDLTKAATGKTIAENFD
                     ALKVIINAAFGVIVNVIKASTPVFQTLFSILGIGASVISFLRPAIIGLVAALVTMRAI
                     NQAVKTTKDLISAWKIFKLTATRAIRIINLLTAAQATYGSITKAQLVAHLANNGALTA
                     SNLLYGVLTGSISLQTAATIAATAATTAFKAGLTAVKAALTALTGPIGLVVAGVGLAV
                     GALVGLWQWLTAESEETKRLKSEQEELVKSTDQLTDSVKQSAKERQKNLESVKGNTES
                     YQKLADEIVQLSQKTNKTAADKKNLKKKIDALNASVSGLNLAYDKNSDSLSHNSDEIK
                     ARISAMEAESTWETSQKNLLDIEQKRAEIGEQLKQIAEQRKKWNEESNVSDGVRKERL
                     QELNDKETELKNTQTELQTEYEKTSQVQQAASEAMAAAAENGSNRQVVAYENMSKSQQ
                     KAIDDMRTKYNELLETTTNMFEQIKYKSAISVDEMIANLQKNQEAVNNWATNLNTLAE
                     RGVNEGILAKLQAMGPQGGLYVQELVNASDEKLATLNEVFTQGGESAMNGLTAGMDTG
                     ALGITDKIKGIVQSQVSSLQEEIAAADFSSLGQEIPNGVSQGIEQGASTAGESSKNMA
                     NDIKESFTSEMDINSPSRVFNEYGGFITTGLAEGVDKGTNQPVSSVTNLANQIKKPFD
                     SLQSDFTYIGEMAMSGLNAGLWSGSGSVMATANSIAERVKATIKSALDIHSPSRAMRD
                     EVGRFIPQGIAVGIEADAGVVEKSMLRLKESMMIDTRPEIALGLNKKLGAQVTVKQSS
                     KQTIAEKIKVTMDKSSELLKKALDVAETAVRRPNEMYLNDGTLVARTGDKFAKYQSEQ
                     LRRDNRMKGVLS"
     gene            33160..34674
                     /locus_tag="VXD01_000768"
     CDS             33160..34674
                     /locus_tag="VXD01_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEV0601199.1"
                     /translation="MTKIMTFNGVDMSKFFRITDIIRPIGNKRSVSTDNAPLLGVNIQ
                     QVKIGEKEHIIKFDIKTTNAIEMEQLKHDLAGILNVLEPVKITYGDEPDKYYMGLPVD
                     EITPENLTRWFQRSELKIIIPDGVAHSTTLKNFDIDTNETSAPDRIVFNLTNTGTEPA
                     YPIIRIKHNSENGYIGVVNNRAAFELGNREEADTEKYRDSETLIDYRGTNILKGFQNG
                     TKGVAVTNDNKERLVGTLSTTSMWGRNHIELSNRGTVEKNRNNAQSLTWAIPVDSSGE
                     VGSLNDYLLWRQVFMAAVANQYGFIKVTVSDTDGNFLYGVETYKRYQTLDCEYSFFTT
                     DGKGGYKFIKWWYFTGTGAQVGKLDPFSAEKGWSELKRNDDRVQVFFDGSHYDFIIPE
                     IKDKKSAKIHITLGALRDWPLVSHMYVDEFMYRKDFVTKSRDIPNRYPIGSNVVINSE
                     DDSVYIDGISKVSEVVDGSHWPAIPPGKSQLELYFSRFVKKKPTVTIEFEERWI"
     gene            34676..>37462
                     /locus_tag="VXD01_000769"
     CDS             34676..>37462
                     /locus_tag="VXD01_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0601200.1"
                     /translation="MLLTIHDANLQKVAFIDNEKQGTLNYYDDTWTRSLATGSSTFEF
                     TVFKKAVKSDLPLAKAYHHLNEHAFVSFKYKGKSFVFNIIIVEENEQTIKCYCENLNL
                     ELINELANPYKSNKAMTFKEYCEAMDLLNYTHLSIGINEISDYKRTLEWEGQETKLAR
                     LLSLAKRFDAEIEFDTQLNADSTIKKFSVNVYHENDDNHQGVGRVRNDVIVKYGKNIH
                     SITRKVDKTGIFNTIRPTGKMPTVEEEPSGDKGSKSETVKNADGSTTKTTISTASDGT
                     KSKTIVHTKVTKLADKTRITTTTTTRSDGSIEQTVTTSKKGGASTSETKVLKKPNPKE
                     KTNTTEDVLTIEGLDEWEVKNEKGIVEFYQRGQALYAPISMQLYPSTFTHSTGELDQW
                     TRKDFHFETDEPNELRRLGYLKLKKYCYPAITYEVDGFVDADIGDTVKVHDDGFAPLL
                     MIQARVTDQKISFTNPVRNKTIFDNFKALENKLSADIQSAFERLFEAAKPYTIKLSTD
                     NGVIFKNQIGQSLVTPTLYKGGKPVVVGVTWRWALDGEVTTGMTYLVRGSNVTDTVTL
                     TVAAYIGNKEVAVDEISLVNVADGKLGTPGTPGRDGRTPYVHTAWANNATGTDGFSLD
                     SSINKLYIGIYTDFEPNDSTDPKKYKWAKVKGEKGEKGDKGEPGQRGLDGLQGARGEQ
                     GLPGRNGADGRTQYTHIAYSNSADGTKDFSVSASDRAYIGMYVDFNRADSNTPSDYNW
                     TLVKGSDGANGVAGKAGTDGRTPYLHIAYATSNNGSQGFSTTDSTNKTYIGTYTDYTQ
                     SDSTDYRVYKWTLIKGADGTGISNVTNYYLATTVSTGITRTSAGWTTTPQPITSDKRY
                     LWNYRVELYTNGTSKTTEPTVIGVHGDKGERGLQGLQGLQGARGEQGIPGPRGADGRT
                     QYTHMAYADNATGGG"
BASE COUNT        12826 a         6240 c         8131 g        10265 t
ORIGIN      
        1 ggcgtggcag gtaaggctgg tgcagatggt aggacacctt atgttcactt tgcgtattct
       61 gaaaatgcag atggatcagg tttgacaatg acagataacg gacagcgtta ttttggtcat
      121 tattcagatt atgagaaacc tgatagttcg gataaaacta agtacaaatg ggctgatcgt
      181 tgggctaaag ttgatggagg ttatgtaaat atctatgcat tgtctaagaa tagaagtatt
      241 gggaaatctt atcatgtttc tgaatttaat atggatgtac tttcagggaa tatcactcta
      301 aaagcaattg ggtcagatcc atacattggc gccgtttctt ctcatccagg tatttttata
      361 aagcaacagg gaatgaaaat cccagttata caagggagat ctatttgtat aacaataaca
      421 aatcctttat ttagaaaaaa ttacatctcg ttttttaatt cattaggtaa aactgttaaa
      481 acatataagc attacaacac aaataaattt ttaatatctt cagctgattt ggtaggtgtt
      541 gaatttatcg ctttacgata tggtgcagga agctcgaata tacaaattgg aaccgtacta
      601 gagacaaaag taaaggtaga atatggaacc gtgcatagcg actggtcgcc cgctccagaa
      661 gatattgaaa gtaatattaa ctctaaagct gatcaggggc tgactcaaga gcagttaaat
      721 gccctcaatg agaagtcaca gattttagag gctgaaatga aagcgaaagc atcgatggag
      781 gcctttagtg aattagaaaa agcatataat gcctttgtga aattaaatgc agatagtcaa
      841 aaaaaatctg agtctgattt agttgaagca ggtagaagaa ttgatttgct gacgacacaa
      901 tttggaggat tagcagagct taaaacattc attgatactt acatgaaaag cacaaatgag
      961 ggcttgatta taggtaagaa tgatgcaagc tctactatta aggtatcaag tgatagaata
     1021 tccatgtttt ctgcaggtaa ggaagttatg tacatttcgc aaggtgtaat aaatattgat
     1081 aatggtattt ttactgcatc aattcaaatt ggacgtttta gaacagaaca gtatcatctt
     1141 aacaaagatg tgaatgtcat acgatatata ggaggttaaa aagagggaaa tgactaaatt
     1201 tatcaattct agcggttcac tacacttgaa tatttacatc gaacaagtta gtcaagatat
     1261 cgctaacaat tcctcaagag ttagttggaa agctactgtt gaccgtgatg gagcttaccg
     1321 cacatatact tatggtaata ttagtaactt gtctgtatgg ttaaatgggt caagtgtgca
     1381 tagtagtcat ccaaactttg acacatccgg gcaagagttt actttagcaa gtggggaagt
     1441 aaccatccca cacagtggtg acggaactaa gacttttgca gtatgggcat cgtttgaccc
     1501 aaacaacgga gtacatggaa acattaccgt atcagcaaac tatactcttt caagcattcc
     1561 tcgatctagt agtgtaagcg acaatgctct ttcaggaaat aggcggctcg gaagtcctca
     1621 cactctcact attgatcgca aatctagctt atttactcac caagtatggt atagagtgtt
     1681 tggtagcaac tggattgatt taggaaaaaa tcacgcaaca ggcgtttctt tcgtacctaa
     1741 tattgaccta gctagataca acacaaaagc aaagtctggc acgatggaca tatgtgttcg
     1801 aacatataat ggaactactc aagttggaaa tgacgtttac tcaaatgggt ggtattttga
     1861 aattccggaa agcgtgaaac ctacattttc tggaattaca ttgactgata tgaatactgt
     1921 tgctaggcaa ctattgagcg gaaataactt tttacagatt atttctgata ttcaggtcaa
     1981 ctttaataat ccatccgggg cttatggttc gactatcaca ggatatcgtg ctgaaatcgt
     2041 aaacaagaat caggttataa ctgtaaacgg tggtaggctt ggtatgatga atttcaatgg
     2101 ttcagcaacg attcgagcta gtgtggttga tagccgaggc aggcaatcag atactagaga
     2161 tattacaatc aatgttattg aatattttgc accagctttt agttttacag cttttaggac
     2221 gcgggaaata cctaacatta ttcaagttgt caggaatgct aaaatcgctc ctatcacttt
     2281 atcaggtagt caaaaaaatg tcatgacact atcattcaaa gtagctcgat taggtagtac
     2341 aacttttaca gctgatcatg gtagagcttc tggtatttgg acaactcaac acaccttaaa
     2401 taattcagct gctaacatgg caggtaatta tgttgcaacc aaatcatttg tggtcatagg
     2461 aactctatct gataagttta caagcacaga atttacagca acagttgcaa ctgaaagtgt
     2521 ggtaatgagt tatgacaaag atggccgtgt gggcattggt aaagttgcag agcaaggtgg
     2581 tgcagggtca ttggatgtct tgggagatat ctacgctaga aataaaccta ttcaacaata
     2641 tcaattgact gacaataatg gatgtggaaa acttatcaaa caggatttta atacgatgaa
     2701 agagactgga acgtggtgga taaatggtag ctctcaaaac aacccctttt ctggaacttg
     2761 ggggatgcta gaggtattca gacctaatcc aggctctcat gaacgtattc aacgcttcac
     2821 tacctcaaca ggatatatgg cagttaggga gaatggttat gataacaact ggagaccatg
     2881 gcgctatctg gtgcaacaat ccaagtctac taataactct gactatgtag ctttgctaaa
     2941 atcagaaagc actccgactc cttggcaaaa tgccatttta caaaatggct ggaatcatca
     3001 cagggattac ggaggtgtcc aattttcaaa aacattcgat ggtgttgttt gttttaaagg
     3061 aacatgtaag ggcggaaaga ttgcacgtga gtcaatcata cttactttac ctgaacattt
     3121 cagaccatct acaacattat tcaaaactgc tctgaataat gattacggtt cagccgttat
     3181 aggaatttat ccaaatggaa acgtagttgt caaatctaat gtagatgcta cttggcttaa
     3241 ttttgataat gtgtttttca aaatataaca accgtaaaaa atccctaatt attaacggat
     3301 aattaattta taaaggagga aatgacaatg ttaaaagtca ctaaaacacg tcagctagta
     3361 actgaatttt tcgcacaaga tggcgaccaa caaaaattgg tcaaaactac tgtaatcaac
     3421 acagacaata aagctgtttc aacaatatct gaaacgctgc atgacccgga actgtacgct
     3481 aacaatcgta tcagtatgcg taagcatgag caagagttac gagaaatgcg ctataagatt
     3541 gaagatgcca ttttggcaga gctggaagca gatgctgagc ataaggaata ggaggtgtgt
     3601 atgaaaattg aatttttcaa ttttctaaga agtgtcgtac agactgaaga tggtttggtc
     3661 ttgtacgctc taacactgat tgtctcaatg gaaatcattg attttgtcac agggacgatt
     3721 gcggcgatta tcaatcctga catcgagtac aagagcaaaa tcggcattaa cgggctcctt
     3781 cgtaagattt caggggttct cttactgatg atcctcattc cggcgtccgt tttgttgcct
     3841 gaaaagacag gttttgtatt cttgcattca atctgtctcg ggtacatcgc atttactttt
     3901 caatctctca ttgaaaatta ccgcaaatta aaaggaaatg ttactctttt tcagccgatt
     3961 gtaaaagtat ttcagcgatt acttgaaaaa gatgatgata cgaaaaaagg agaataacaa
     4021 atgcaacaaa ttactgaaat cattactaat ggagcaatca gcatcctagt cgttttggca
     4081 ggggttgtag ttagggcagt caaggactac ctggttcaaa aaggtggaga aaagaccatc
     4141 aagattgttg aaatcttggc caaaaatgca gtaaatgccg tggagcaggt agctgctgaa
     4201 actggctaca agggagatga aaaactggca caggctcgcg ctaaagtccg tgctgagctt
     4261 acaaaataca atattagtat gactgacaaa gacttagaca ccttcgtaga gtcagcagtg
     4321 aagcagatga atgacgcatg gaaaggacga tagggaatgg atatcgatag aaacagacta
     4381 cgtacaggct tgccccaggt tggggtgcag ccttatcgac aagtacatgc tcactcaaca
     4441 ggtaaccgca actcaaccgt acagaatgaa gcggattatc actggcggaa agacccagaa
     4501 ttaggttttt tctcgcacgt tgttgggaac ggtcgcatca tgcaggtcgg acctgtgaac
     4561 aacggaagtt gggatgttgg gggcggttgg aatgctgaga gttacgcagc ggttgaactg
     4621 attgaaagcc attcaactaa ggaagagttt atggctgact atcgcctcta tatcgaattg
     4681 ctacgcaatc tagcggacga agcaggcttg ccgaagactc ttgatacaga cgacttggca
     4741 ggtatcaaga cgcatgaata ctgtaccaat aaccaaccaa acaaccactc agaccatgtg
     4801 gatccatatc catatcttgc aagttggggc attagccgtg aacagtttaa gcaagacatc
     4861 gaaaacggct tgagcgctgc aacaggctgg cagaaaaatg gcactggcta ctggtacgta
     4921 cattcagacg gctcttatcc aaaagataag tttgagaaaa tcaacggtac ctggtattat
     4981 ttcgatggct caggctatat gctttcagac cgctggaaga agcacacaga cggtaattgg
     5041 tactactttg accaatcagg cgaaatggcc acaggctgga agaaaatcgc tgacaagtgg
     5101 tactattttg atgtagaagg tgccatgaag acaggctggg tcaagtacaa ggacacttgg
     5161 tactacttag acgctaaaga aggcgccatg gtatcaaatg cctttatcca gtcagcggac
     5221 ggaacaggct ggtactacct caaaccagac ggaacactgg cagacaagcc agagttcaca
     5281 gtagagccag atggcttgat tacagttaaa taaatagaaa ggaaactttc taaattgttc
     5341 tttcaccgca ggctcaggct tgcggttttt ttgttttaaa aaaggggcaa aaaaggggca
     5401 aaagtgtcgt aaacctctgt aaaacgatgt aaaaaatcaa ctttgccctc gctttaaagc
     5461 tctaaatttc aacgtattgt gaaacagtgt aaattatcgt atcgcctata attgttgtgt
     5521 gctctttttt cgtgcacttt aaaaaccctt taaaatcaac actttaaggg gtttttgttt
     5581 gtcttgtata agaaaaaggg gcagacgagg ggcacaattt aaaattttac cttgtctaac
     5641 ttgctagata tgtctgatac cattttttga gtaacgtgag aataaatctc tagtgtggtc
     5701 tttgagtcac tatgccctac tctgtccatg atggcagtca agggaatgcc cagctcagca
     5761 agtagggata tgtgagaatg tctaaatgta tgtgtagtta tgtttttttc tatgccgatt
     5821 ttttgaccat gtcttttcaa tgcacaaata accctggcat ttgttattgg ttctcctaga
     5881 gtattgatga aaataaaatc tgtatcaaat ccatttgtcg cattctctat tatttgctct
     5941 ttgataatat ctaacacttt ttgaggtgct gttataaccc tatcggactt gattgtcttt
     6001 ggtgtagttc tctctttttg tctgaaatcg tatgtatgct tgatgtgaat agtcttttta
     6061 gaaaaatcta tatcttcctt gtagtttaag gctgccagct ctccatacct catgccagta
     6121 agaaaaagaa ctttagctat tcggatatac tttgtaattc gataatcaca tagggcctcg
     6181 tcttttaaat tttggatgaa taacttaaac tctttttggt ctaagtattt tgtatttttc
     6241 tttctgagtt cgtcggatgt aattactttt ctaggcgttt caacaaatag catttcattt
     6301 gtatcaatat aattcattct gatagcgaat ttcattatct gattgagctt gaacttgatt
     6361 ttagaaacat agttatgaga tctcccatct tgtaatagtt gatctattac tttttgtaat
     6421 aaacgtctat caatatttct aactaggtag tcgccctcta tctgctttaa aatctctttt
     6481 tttacatttt ttgaagcata gactgttgaa tttttaacac catgtttcca attttcctca
     6541 aattcctcat atagtttttc aaaagttata ttagaaacag aatgttgttt ttcccctaac
     6601 ttttgtttta tcttttcctg caacaagatg gcggcttgat ttcttgcttg tggagttttc
     6661 ttctccatgg ttactgaaac tttttttaat ttctcagtat aagggtcttt gtatcgctca
     6721 aaatatttaa acttgccatt tggcaattct tccatccaca ttgattttac ctcacttttt
     6781 tgataaaatg ggtataagaa aacgaccttt tgaatggttg tttcctatac atgatttcct
     6841 cacactcaag atttggcgat gacgagtgtg gggatttttt tatttcgttt caaagaaatt
     6901 tccgcaattt tggcaatgcc actgtttatt tccttttttg ccagcaaatc cagctaaagc
     6961 accaactcca ccagtcaaaa cagctccacc aacggccttt ccaacagaaa aggctttttt
     7021 gtcttgttgt aagaaagtca catctttaga cttacaatta gggcaagtga tgatattctg
     7081 ctttttctct tgctttttct tctcttgatt tgctctaaat gtttcaagtt cacgttctct
     7141 ctgctctgga gatttttttt ggttatcaat tactgcacct atgacacctc caacaaaaat
     7201 aacaattatg ataatagcaa ttatattcat tttctctcct tttttaatta agtagtgcta
     7261 aatattcttc tttgaccatg atttcatcgg caatggtttt taaattatac ttttccataa
     7321 ataccaggta attaaatgta gtggcatctt cggctatatc caactcagct ttcataaggt
     7381 gatggatcat attcctatta gcctcaagct cacacttttc cctaaaaagt tgataagtat
     7441 ctggcgcgtg gtttctatgg cctatctcat gtaaagcgac ttgtaccctt ttttcatcag
     7501 atatagcatc actcaaaaac atagttttga gggctgggat gtaaaaggct tcatctggaa
     7561 atagaccatc ttcaaaaatc tctatatcta tacctagatt ttgagaaaat tctttttcag
     7621 tcataaacaa tccaaccttt tattattatt gctttctgag ataaatctct attatgtttt
     7681 gaattgcttt tttatcttct tcagttagtg gtttaccatt gaagcgcata gcggtagagg
     7741 caagttcctc aacatcgact tctttgcctt cgaaaaagaa ttgttctttt ttattagcga
     7801 tggtaggatt atctgtgcga ccaagtaagt agtctgtaga tacgttgaag tagtcagcga
     7861 ttttttcaat tttatcgccg ctaggagttg aagtttccca ttttctgaga ctgccattac
     7921 taaaatttaa attcctttcc aattcggcaa gagtaacctt tctatcattg gctaacgagc
     7981 gtattctatc taaaatagtc atgtgtaaaa acctccaaaa ataaggcttt acaaaataat
     8041 gtaaaatttt ctactaaaat gattgacaga tagaaaattt tccgttatac ttattttgta
     8101 agctagttga ccagctgaca taaatacaaa tagaataatc cgccaagatt ttcgttatat
     8161 ctgtttttat gatatagctg tattttttat acccttataa tagactattt tctattattt
     8221 gtcaatgaat aatgcttatt ttcttataaa attttctatc aaaaggaggt gccggaagtg
     8281 atttatgaca aaataaaaga aattgcttca gagaagggga tttcgattta tagaatcgaa
     8341 aaagatcttg atttaggtaa cggggcaatc agcaaatgga acaacagttc gccatctgcc
     8401 actactctaa attcaattgc aaattattta aatgttcgtc ttgaacaatt gctggaggaa
     8461 taacatgaac gaactcatca acgtaaccct gaatgacaat caggagccag tagtgtcagg
     8521 aagacaacta catgaggcgc tgggtgttaa ttcaagatat acaacatggt ttgaccgtat
     8581 gaaggaatac ggatttacag aaggtcagga ctttctccca aatttgggaa aaagtacagg
     8641 agggcgacaa gctactgacc acatcatcaa gctagacatg gccaaggaaa ttgctatgat
     8701 ccagcggacg gagagaggca agcaagtccg acaatacttt atccaagtag aaaaagactt
     8761 taatagccct gagaagatta tggcaagagc attgctcatg gctgatcaga aagtccacaa
     8821 gctggaggct cagattgaag cggacaaacc caaagtcctc tttgcagacg cagtaagtgc
     8881 aagccataca tctatcttgg ttggcgaact tgccaagctc attagccaaa acggctacaa
     8941 aatcggtgcc aatcgcctct tttcttggat gcgcgaaaat ggctacctga ttaagcgcaa
     9001 aggctcagat tggaacatgc caacccaacg tagcatggac ttgaaactct ttgaaatcaa
     9061 ggaaacaaac gtgcaacacg cagatggaca tatcactgtg aacaagacac caaaggtcac
     9121 aggcaaagga caacagtatt ttatcgataa gttccttaat taggaatacc tgacaggtta
     9181 gaaagtagaa agaatgattg aaaataagtg aagagaaagg agactgtatg acagacttta
     9241 aaaatttaga ttgtcaattt atctttcaag aatgcgactg aaaattatac tgctgttagt
     9301 aatagtttta tcaacgatcc tgcgctggat tttacagcgg ttggcatcat gatggtagtg
     9361 ctggctaatc acccaaattg gcaagtctat ccggatgaga tagctaaaag aaaaggtgtt
     9421 aaccgaaaga caatcgataa gtatttcaaa atctttgaag aggctggata tttacgaaaa
     9481 ataagaaaaa aacctcctgg aaatggaggg agtcatatat tcagattctt ttcagatgta
     9541 aaaatatctg atttccaatt cgatattatg aaacagagat tgaacctatc tatcaaaagg
     9601 gcgtctatga attataattc tgacattcca aaaagtgaga tgtcagaaag tgagatgtca
     9661 gaaagtgaga tgtcagattt tgggcactaa taaatactaa ctaacaacaa gtattaaata
     9721 acaataaata ctaactaaca acaagtacta ctcttaataa ataaaagaga gtatacaaaa
     9781 aagtatctga gaaactcaga cactttctaa aaaaatctaa cttaattata gcatgaaagg
     9841 ggaaaaatgg aaacagttca aatcgtgaga attaaagatg tgatcatcga gaagatttct
     9901 gcaaacgatg aagaactaga gcgcatcttt ggatgttcaa aacggcaagc gggagatatg
     9961 aggcgagaga tgaaaaaatt gcctagtcag caaaaatacc ttagaaacga tggtcagctt
    10021 gtcacaatca aaggttttga tgcttatctg caatatcgag gcagtcaatc atggaagaaa
    10081 gaaatggcta aaaccgttaa gatgacacga tagcagaata ataactacta acaaataaca
    10141 aactcatact tatagataat aagggaatta cagagttttt aaaggaggaa agaaatatgc
    10201 caaattgggc agagggaact cttaaattaa gaggcagacg cgaaaacgtt gcatcagctt
    10261 taaaagaaat gctattagga gatgaaggcg caacgcttga agaagaatac gatggcactc
    10321 tactaagatt taaaaacgag tatgattatt tttatataaa cggtacaaga cgtgcgttta
    10381 tttctagtaa agatattgaa atttggttgg atgatgattt tgtgattatc gaacttgaag
    10441 atttcgaaca agcatgggca gcattagctg acaattacac agaaatttct agtaagtttg
    10501 atgttgatat taaaattttc acttttgaaa tgggtatgga atttacacag gaaattgaaa
    10561 tttcaaaagg tgaaatcatc aagaatattg taaacgaaaa ctttactaac tattcatggg
    10621 atgtgccttt tagtagactt ggaggataga taatatggct gatttaacat ttgcagaatt
    10681 acagcgaaaa atgcaaatcg aaaaacaaac gaaacaggga gtgaaatatc cgtttagaac
    10741 cgcagaggac ataaataata aatttaagtc tttggatagc ggttggagtg tatcatttcc
    10801 agaagatgac atcattcaaa aaggtgacaa actgtattat aaagcggtag ctgttgctaa
    10861 aagagaaagt gatggcacga ttgaaaaagc tattggatgg gctagagaag aagatgtacc
    10921 aatttttcac acacaaaaag gggatgtgaa acagatgcaa gatccacaat ggacaggtgc
    10981 ggttggttct tatgctagaa aatatgcttt acaaggttta tttgccattg gaggtgagga
    11041 tgttgatgag tatccagtag aagaaagcca agagcaagga cagaataatc agcaacagaa
    11101 accaaacaac cagcaagccc aaggacaaaa tcaagtaagg tatattgaca acattcagta
    11161 tcaagaaatt aacgacctta taaatgatat tgcaaaaatt aaagggatgc cgttcgatac
    11221 gcttgctaac tatgtactat ctgaaaaatt aaaaggttta caagattttc atagagtaca
    11281 agttggtgac tacgaggtat tgaaaaacta tttaactgaa caactagcaa aagcaaaagc
    11341 aaagagaggt aattaaacat ggtaaaagat gtaactaata gcttgacaga aatcaaggtg
    11401 gattttcaac ctgcagtaat taatgttgac cgtgaggcga tcgaggcaca agtagccgca
    11461 gccattgcac agtatagcgg tcgcgaggtt actgttgata attacaaaga agtttatgaa
    11521 gagcgaaccc gctttaataa gctgattggg ggcttagaca ctcaacgcaa agattttaac
    11581 cgacaaatca atgagccggc aaaagacttt gataagtggg tcaaagaaaa agtcatcaag
    11641 cctattgagg gcgtaacaga tgctatgtca gcaggactta atgcgattga tgaacatgaa
    11701 cgattgatgc gcgtggatgt cgtgcgtgct acatttgagg ataagtgtat ggtcgcaggg
    11761 attgaaaaat ccacattcgc tgacaaatac gatgagtaca gcctcaagaa atattttaaa
    11821 acaggcaagt atgagctgaa aaagacaaca cttgatgaaa tggatggctt agtactttca
    11881 gaatttgatg ccctggaaga atacaaggct aacaagcaag ctatccaaga gcaagctcaa
    11941 gagtacgatt tgccagctga tagctatatc agacatcttg aagatggtaa gagtcttgtt
    12001 gatatactca agatgatgaa aactgaccga gatgctgaga ttgcacgcaa agagcagaaa
    12061 gaggctcaag aaaaagcaaa agctgaacga cttgaagaaa ttgctcaatc ggccaagaaa
    12121 aatgctaatg cgaatatcaa ggcttacgat gccgaaacag gcgagatttt ggaacagggt
    12181 acaattacac cagaacctca aaacaatgcg cgagaggtgg caaaatttga gcctagcgag
    12241 cctttggtca aattagtacg tcttgaattg cacggtggtt tagaacagtg ggaaaataca
    12301 caagaatatt ttgaggataa ctttatcggt tttgaaactt tggaggatta agtagaataa
    12361 ggagtcagac ctatgagatg tttttatgtc agcggtaaaa ttgcagatct tgatttgggg
    12421 tcagaaatca atgcagaaaa ttcatttatg gccgctattg agtttgtgaa acgatatacc
    12481 ggcttattaa agtttggttc aaatgaaatc aaggtatcag aagtagagga ggtgcaaaat
    12541 gataaataac gttgttttag tagggcgact tacaagagat gccgaactga gatacacgca
    12601 atctaatatt gcggttgcta cgtttactct tgctgtaaac cgtccattta agaacgaggc
    12661 tggagagcgt gaggctgatt ttatcaattg cgttatctgg agacagtcag ctgaaaatct
    12721 tgttaattgg gctaaaaaag gttctcttat cggagttaca ggagtaattc aaacacgtag
    12781 ctatgataac cagcaaggtc aacgtgttta tgtcacagaa gttgttgcca gtaattttca
    12841 actgttggaa agtcgtaaca gtcagcaaaa taatcaaggt catcaagacc atcatggcgg
    12901 ttatcagcag cagggctaca gtaatcaagg cagttctttc caaaatggaa atagttacgg
    12961 gcaacaaggc agtttccttg aggggaacac aacaaatcta gttcctgatt tcacccgtga
    13021 taacaatcca tttggcagac ccacaaatcc attggatatt agtgatgatg atttaccgtt
    13081 ttagcgaaag gggatattct agttaagtta tgaaattctt agacttattt gctggcattg
    13141 gaggttttag gatcggcatg gaatcagccg ggcatgaatg tataggattt tgtgaaatag
    13201 acaaattcgc tagagctagt tataaagcta tacacgatac gaaaggagaa attgaattac
    13261 atgacattac aacagtatca gatgacacta ttcgaggaat cggacatgtt gatgttatct
    13321 gtggaggatt tccgtgccag gctttcagca ttgcaggaaa cagacgagga tttgaagata
    13381 caagaggaac tctcttcttt gaaatcgcaa ggttcgcatc tattctcaaa cccagatatc
    13441 tattccttga aaacgtcaag ggactcctca accacgacag aggaaatacc tttgaggtca
    13501 tcctctcagc gttggatgaa ctggggtatg atgtggaatg gcaagtgctt aacagcaaag
    13561 attttggagt cccccaaaat cgggaacgtg tgttcattat cggacattct agaaaaagag
    13621 gcaccagaag agtttttcct atcggaagag caaatagaga atttgatttt gaaccaaaaa
    13681 taaagattgt tggtaacact aaaaatccga acgggacaag tcaagggact gggagcgttg
    13741 tttacgactc aaacggttta gtcggtacgc tttgcgctag agattataaa gagccaaaac
    13801 aagtagctat accagtattg acacctgata gagtaaataa acgacagaat ggtagacgtt
    13861 taaaaaaaaa cggtgagcct atgtttacgc tgacggcaca agaccgtcat gggattttaa
    13921 ttaaagaagc aacaaaaaaa ggttatgcag aggctacagt tggtgatagt gtaaacctat
    13981 ctcatccaaa ctctaaaaca aggcgaggta gagttggtaa tcagatagca aatactctct
    14041 taactggaga gagtcaaggt gtggttgagc ctgattttag gattaggaag ctaacaccta
    14101 gagaatgctg gaggttacaa ggttttcctg attgggcttt tgataaggcg caggaggtca
    14161 actctaacag tcaattatac aagcaagcag gcaatagcgt aacagtaaac gttatttctg
    14221 caatagcaca gggtttagga ggaaattaac cctatttaaa ccaatttgaa aaggaaacag
    14281 aaaatgacaa aaattgaaat cgttatggta cttacaactt tgatgtctat cacatgggca
    14341 gcgattgtta caattcacac tatgcaagct atcaaaaagc acaaggcaaa agtggattat
    14401 tatcagaaac cacaagtgca atgtgagatt gcacgtcatg tacttaaaaa caaatggtac
    14461 tcagatggtg gggaggtgtt tagatgaaag tatttgatgg cgctatttca aattagctta
    14521 atttaaagca ggaggacaat atggataaaa aacttattgg gttagatcta acccacattg
    14581 cagatggagg attacaggag aaactagaca aagagcttga aaaagtcttt gataacatcc
    14641 ttgacctaaa tacagatgcg aaagcaaaac gaaaagtgac tatcacactt acaatgtcag
    14701 caaatgaaga gcgtacagtt gttgatacta ccatggaggt gaaatcaaaa tttgcgcctc
    14761 aaaatggagt agctacaaca attcttattg ggcgtgattt tgatacaggg caagtacatg
    14821 ctaatgagct aaaaagtaca gtacctggtc aaatgtactt tgatgaaaac ggagaaattc
    14881 tgacggatat tgggcaacca gtggcagaaa ttgaacaaca agcagaaaca aaaccagata
    14941 ttattgattt caacaaaaag aaagtaggta actaatatga caacagaaaa tcttaaagca
    15001 gcattggaat acgcagtaga actaaatgag catggtttgg aaattttaac agctgcagat
    15061 ggaacagagt attatgatgc caacaaattc aacctcaaag aacttgaccc taaacgctat
    15121 cctaaaactc tggagctatc aaccttgaca agccttgttg actatctcaa aacagaccta
    15181 aacaatttga aaaaccaacg cttgattgta gcagttgaga aaaatgatga ggtttgtgtg
    15241 tggtctgaaa atgatgagtt agaacgtcgc acattacttg ttgatgttaa ggcacgcatc
    15301 ccagagttat cttttggccg tttcctatca tcggaacagt tcaatatcat gttgcaatca
    15361 aactttattg acgataacga tcgtggcaca ttgctagaat ttgctagcgc attgaaaatt
    15421 gagaatgggg ctgaaattga agataatgga gtatctcaag tagcaacagt taaaacaggg
    15481 gtggcaagcc ttgctaaagg caaagcacct aatccggtta cattgcgccc atatcgtaca
    15541 tttagcgagg ttgagcaacc ggcaagccta tttgtcttta ggattgataa gcaagccaat
    15601 atggctttat ttgaggcaga tggtaagcgt tgggtagctg atgcagtagg aaacattgca
    15661 gcctatctaa aagagcagct agcagaccaa aaacttatca cagtattagc ataagaaagg
    15721 ggaaattaaa atgagtgatt acaaacaacg gatgattgaa gaatacaaac aattaaaaga
    15781 gcgcaccaat aagttaagtt tgatgattag taactattac gtaggaacac ttgattttaa
    15841 actaaaatgt cctattgagt tacttgaaac tcaacactat acaatgtgtg catatctcaa
    15901 gatccttgaa cagcgtgcag aaattgaaaa cattgagttt taaggtaatc aaaatgaaat
    15961 ttgagttttc tttgcctcgg aatactaagc taaaatctct aaacatggtt atcaatagta
    16021 atgacagaca acatcaaaca gataaggcta aagttactaa gcgcattaga gcttttgctt
    16081 attggcatac atcaatgaac aaggataaag ggagggctgc ttttagcccc tctaaccctt
    16141 gtgaggttac agttacaatt tacagcccta ctaagtctaa attagatcca cctaacttgt
    16201 atccgacagt caaggctatc attgatggca tgactgatgc aggtatttgg acagatgata
    16261 atcataaggt tatcaaaaag ttatcctttg tttatggtgg cttaagtgag gaaaaagggc
    16321 attatagatt agagtttgat atagaggagg tttaaagtga ttgaagttaa tataaaattc
    16381 gataattttg aagcgcatgg cttttaccaa gatgatacta aactaggaaa aattagagat
    16441 gcaatcatat ctcaaatgaa taatgggcat gtggttattt taggggaaga tagaagtatt
    16501 ctattaaatc ctaaagttat taaatgtgta caatttgagg ttgtagaaga tgaccagatc
    16561 taatcgtttt ttgaccttta gagaatctga gttattttga ggaggtggag tgatggaaga
    16621 gttaaagaaa aaagttaatg aagtatacaa ctggacggta gaagacggga agccgcaacc
    16681 tcccaagcaa gatttaccac aagcggtgaa agaccgagcg gactattttt gggaaatggc
    16741 agaagatggt atgacgttta tgggagcgat ggaatgcatc ttcgctgatg aaaagcctac
    16801 agactatgat ttgggagcta ctaaggattg gttgccaaaa tctaaggagt ttgatgattg
    16861 gattggctat gcgccaagca tggctcaggt agttattgca gtttatttga tttatagagg
    16921 aaactaagat gaatattaag gcattgatta agaagtatga agaattgtgg aatgaacaca
    16981 gcccttttta tgaacctgta ccttatactt caatggttga actttttttg aaagagttga
    17041 aacaactaga cgaaccagaa aaagtcaaag ttccgcagtt tatggcggat tggattgatt
    17101 atttcaaaaa aaatggtgac tgggatttgt ttcaagcgat ggattatttg tttggaaaaa
    17161 aagaaataag ggaatggctt gagtataaaa acaaccaaga cctcttcgct cgtgcttggc
    17221 ttgacggcta cgaggtcgag aaagagaagc ggtatttggt gactttaaaa aataggcagc
    17281 ctttggtcaa atcgcaatca gggagtactc tttattttag tcaagatata acagctagga
    17341 attataaagg tactcaaaaa gaactagaag acgcaaagtt cggctgggta tttgattgcc
    17401 cagggattga gattgaggag gtgaagtaat gacacaaaca cttgaagaag ggatgaagaa
    17461 tcaaagtaaa tgcataaaaa tacctatgga aatcagaccg tttgatatag ggtatcgaat
    17521 agtgaatcaa catggaaatc cgcttgcttt aaaaaacgga gcaagtatat tcgatttacc
    17581 ttcgctagct gaaaaagcta ttaagaaaga gtttagtaaa gatgacccag attttgatat
    17641 tgaaaaacat ttcgttgaag aggttgctat tgtcaattta agtaaatttc atagttattt
    17701 tgaggaggtg atacatgact gatgacgaag aaaaaaatag agcgcttgtc agttatccat
    17761 cgcagggaaa tcaattggct aaagtggtat tttttgagag ataagaaaaa tccgaagaga
    17821 acaattctgg agcaaaaaat tatagtttct catatcaaaa ctgataggct tgaagctaag
    17881 tttttaacta acttaaaaaa atcaactgaa gattttatag atgggtctga tcctaaatat
    17941 ttgcgggcga taaaagaggt ttatgtttac gaaaacatga atgtcattgg agcttgtcaa
    18001 aaaatactat tttatagtcc gactcaagcc tatgtattac ttaatgcgtg gtttaacgat
    18061 tattttcgtg cgacttacac agaattacta gaaaacgcca tcttagataa ataaccgtaa
    18121 aaaatccaaa gcttatgtat ctataatcaa gatatataag ctttttcgaa aggagagata
    18181 tggagatgtt acagattgaa tatgtagata taaaatccat taaaccatat cacaaaaacg
    18241 ctaggcataa tgacggagag gcaacagaga aagttgctgc atccataaaa gcttttggtt
    18301 ttcagcaacc tatcttagta gatgataata acatcattat tacaggacat actaggctaa
    18361 aggctgctct ttctttaggt atagacacaa tacctatcgc tcacgctgta aacctcacag
    18421 atgagcagat aaaagcttat agactagcag ataatcgagt tgctgagtat tcaacgtggg
    18481 actcagaatt attaaatatt gagctttctc aatttgaaac aatagatatg gctcagtttg
    18541 gttttgagtt atcagttaca gggttcaact ttggtaacga ggaggagcag caagaggaaa
    18601 ctgaaaacga ggaggaagat gctgaggatt ttcatagaga taccacaata aaccaataca
    18661 acctttttaa ttatgacgat acaagggttg agggttttta taacatgcct aaaatcgagg
    18721 gcgtggatca tattcctaaa gattttcaag gctttaatta tgttttaaat aaaccagatt
    18781 acagctcatg cgtgcatttt ttcctagatg attatcaatt tgaaagaata tggcaaagac
    18841 cagactttta cattgaaaag ctgctagaat ttgatagcgc cttagctccg gattttagct
    18901 tatatcttga tatgcctatc gctatgcaag tatggaacat ttacaggtca aggctgatag
    18961 gtcagattat gcaagattac ggccttacag ttatccctac tgtatcgtgg gctagtgagg
    19021 aaagctttga tttttgtttt gacggcttgc ctaaaaactc aacgctagca atcagtacaa
    19081 taggcgtaaa gcaaaacaaa gagcagtttg aggtatggaa aaatggagtt actgagatga
    19141 taaaaaggtt gactccaaaa agaattgtag tatatggcgg aaaagtggaa tacgattata
    19201 aagatataga ggttgtatat tttgaaaatg caacaacgga aaggatgaaa gaaagtggca
    19261 caaaaactaa ctaaactaaa agatattttt aaacatgttt caagtattga tctaggtaaa
    19321 gagattttat ttgaagatct tgagctttac aataaagaaa cagaaacaag caaacaatac
    19381 caatctatcg aggaggcaga aaatgaccta tctttgatgg aaaaagtaaa taaaatcaat
    19441 ttcactctag gcggtggacg tggtgcaaat tttgagaaag ggaaagacgg taagtatccg
    19501 ggttttagag gtgctggtgg tgcaagagat agtgggagct caaaagcctt acatccagca
    19561 tctttaaaca atcaagggcg cttttcaagt gttgagggag ctattcaggg atttattaaa
    19621 aaacacggtg gctctagaac agaatacagt acagcagttg actctcaagg ctttgctcat
    19681 aattatgtac acggtgggaa aaacagcgta caaattttgc ctatctctgg tggatttaca
    19741 gcaatacata accatccgaa tggcagcaat ttctcaagta cagatttaca tagctttgca
    19801 gcattaaaag gtatgaatac actagttgca acgaatagct ctaaagcgta tcgaattaca
    19861 aaaggggcta actttgatgc taaaggcttt gataaagctg tgagcaagtc acgttttact
    19921 acaaaagatt acaataaagg agctgaccta tggctcaaga aaaacgctaa gaaatacggg
    19981 tacacttact catacgagta aaagaaaaga ggctaaggta tgggtggtag aggagcaaaa
    20041 ttaaacttgt caacaacgaa aatgacaact caaaatatag agacttgatt aacaaaatcg
    20101 aaaagttatt aggaatagcg taaaacatcc ccttttttaa catatacaat gaaatcataa
    20161 gtataaaatg cttgtgattt ttttgtttga aaggagggtg gaaattgcct agagatggaa
    20221 ctaaaaattt aaaaccagtt acagaacgaa ccaaagatga agcaagagct attagctcaa
    20281 aaggaggtaa agcatctggc atagcaagaa gaaaaaaagc tgatctcaaa aaagcatttg
    20341 aaaccctctt atctttggat gtgacggata gtaaaatcaa gaaacaactt gaggagatgg
    20401 gtatggctgg caataacgag gctttgctag cctttgcaac ctttcagcaa gctgtaaaag
    20461 gcaatcagaa agcgactgag aacataatca agctgacaaa tactaaagat aaatacgata
    20521 tacaagaaca gaaagagcgt attaaagcac tcaaatatga aaatagagag cgtgctgaag
    20581 ctgagaaagg ctcaagtgaa actatcgaga tagtggatgc atgggctgaa gatgtgaggg
    20641 gggcaacgga tgacctttaa tgtccagaag aacatcaacc ctcatttcaa atctgtttgg
    20701 atttctagct taccttataa tgttttgaaa ggtgggcgta actcttttaa atcatcggtt
    20761 attgtactta aactagcgta tatgatgata aggtatatta tcgctggaga ggcggccaat
    20821 atcgttgtta tccgtaaggt ggccaatact attagagaca gtgttttcaa taaagtttgg
    20881 tgggcattga acctttttgg tatagctgag cagttcacaa aaacagttag cccgtttaaa
    20941 atcgtacaca aaacgaccgg ctcaacattt tacttttacg gacaagatga ctttcaaaaa
    21001 ctcaaatcaa acgacattgg aaatatcata gcggtttggt atgaagaggc tgctgaattt
    21061 aatgaccaag aggactttga ccaatcaaac gtgacgttca tgaggcagaa acacccacgc
    21121 gccaagtttg tacaattctt ttggagttac aatccaccta gaaatccata tagttggatc
    21181 aatgaatggt ttgagagcat caaaacgaat aagaactatt tagctcactc aagcacctat
    21241 cttgatgatg aactcggatt cgttactgag cagatgctag aagatataga gcgtatcaaa
    21301 gagaatgact acgattatta cagatactta tatctaggtg aggcagtggg attaggtaac
    21361 aacgtgtata acatgagtat gtttcatgct attgatgctt tgcctagcga tgataagctg
    21421 attggcatat catttgcgct agatggcgga catcaacagt cagcaacagc ttgttgtgct
    21481 tttgggataa cagctaaagg aaaagtaatc ttacttgata cctggtacta ctcacctgct
    21541 ggccaagtgg tcaagaaagc acctagtcag ctatccaaag agatatatac ttatatacgc
    21601 tcagttattg agaagtacag agtacaagcc ttgcaataca caatagatag tgctgaggga
    21661 gcattgagaa accagatgtt tcttgacttt ggtttgaaat ggcatccagt cgctaaactt
    21721 agaaaagtga ctatgattga cagttttcaa tctttgcttg ctcaaggtcg cttttactat
    21781 ctcaacaccg aaaacaacaa gatatttatt gaagaacaca agatgtatcg ttgggatgaa
    21841 aagactatca aatctgataa tcctagcgtt atcaaagaag atgaccatac atgcgacaca
    21901 acacagtatt ttgtgttaga caatgcaaaa ttgctcggtt tgcgtgttgg taacgtttag
    21961 aggaggacga tcatgagcct atttcaaaaa gtaaaagact tttttagtcg agggaggtat
    22021 tacatgcaga catcaaacct taatagtatt ttggaacatc caaaaattgc agtgactcaa
    22081 gaggagtatg accggattaa gagaaatcta gtctactatc aatcaaaatg ggatgatgtt
    22141 cagtacaaga atacggatgg agatattaaa tcccgtccaa tgaatcactt gccaattgca
    22201 agaacagcat cgaagaagat tgctagctta gtttacaatg aacaggcaac tatcacaaca
    22261 aaaaacgaaa ttttacagaa atttttggat gacatgctaa ctaacgaccg attcaataag
    22321 aattttgagc ggtatctaga aagctgtttg gcacttggtg gcctagctat gcgcccttat
    22381 attgatgggg ataaggtcag agtggcattt attcaagcgc ctgtgttctt tccactagaa
    22441 agcaacacac aagatgtttc aagtgctgca atccttacta agactatcaa atctgagggg
    22501 cgtaagaacg tttactatac ccttgttgaa tttcacgaat gggtaacagc agacggacaa
    22561 gaaacaggta gcacaaacga taaaaagtat tatcgtatta caaatgaact ttataggtca
    22621 gatgtgaatg atgtgttagg tcaacgtgtg aacttgagtg aactagacaa gtacaaaaat
    22681 ttagagcctg taacagtctt tgaaaaccta tcaagacctc tatttactta tctaaaaact
    22741 ccaggtatga ataacaaaga catcaacagc cctcttggat tgtctatctt tgataacgca
    22801 aagacgacta ttgacttcat caatcgttct tacgatgaat ttatgtggga agtgaggatg
    22861 ggacaaagac gagttattgt gcccgaacat ctaacacaaa gacaatatca acgtccagat
    22921 ggaacaatag attttagacc acggtttgat gttgagcaga atgtttatat gcaaattggc
    22981 ggctctagta tggatgccgg gggcattaca gaccttacct caccaattcg agcaaatgat
    23041 tatattttgg cgatttcaga gggattgaaa ctctttgaaa tgcagattgg tgtatcaagt
    23101 ggcatgttta cattcgatgg tcaaggaatg aaaactgcaa cagaaattgt cagcgagaac
    23161 tcagacactt atcagatgcg aagtagtatt gtcgcacttg ttgaacaatc tatcaaggag
    23221 ctttgtgttt caatgtgtga gctcggtaag gcggtagggg tttatagcgg agaaattcca
    23281 gaacttgatg atatttcagt taatttggat gatggtgtat ttactgatag gcatgcagaa
    23341 cttgattatt gggctaaaat ggtagccgca ggattctcaa ccaaaaaacg ggcaattggt
    23401 aagacattaa atatttctgg tgttgaggca gaaaaagaac tcaatgctat caatagtgag
    23461 ttgctaccta tgaatgatgc cgaacttgct atttatggta tgcatgacca aaacgaggag
    23521 gaagcagatg acaaaggtta aattcggagt tactagtgtt gactactcag caagcattga
    23581 agatacgcca acaataaaac taggtttaat aattagaggg agcgggagac tagatgcctc
    23641 ttcagttatt aaaaaactaa tcaaggatgt ttctgaacta gaatacgaat tagaagaata
    23701 aactggtcaa ttggccaatt ttctttcaag agagggcttt tgaatgaaaa aaaagagaaa
    23761 acagatcacg tttaacgacc aacaatttcc tttgcaaatg caaggcgttg gggatattta
    23821 cgaaaaatta cagattgata tctttgaccg tatgataaaa cgcttaaaag agcgtgggtc
    23881 tattgattta atgagaaacc cttatatctg gcagttagag aaactaaatg atatgcacat
    23941 gctcaatgaa cagaatctaa agcttatttc agagcgtaca ggaattgctg aaagattgtt
    24001 gcgtgatgta attgagaatg aaggtttgaa agtctataag gacactaaac agcaacttga
    24061 agaagatttg aataaaatac ctgagggaga gatttcaaat ggcgtaacgg acagcttaga
    24121 ggcttattcg aggcaagcag ttagtgattt aaaccttatc aatacaacat tacctaagag
    24181 cttgcaagta gcttataaat cgattgtgga ggagacagtc gcacaggtag ttgcaggaac
    24241 taaaacaagc gatgttgctt tgcatgatac catcatgaaa tggcagaaga acgcttttac
    24301 gggctttgtc gataaaggtg ggaggcattg gaaagctgat agctatgcga gggctattat
    24361 caagagcaca acatacaaag tttataacga aatgcgtact agacctgctg aggagttagg
    24421 agtagatact ttttactatt cgatgaaagc aatggctaga ccagcttgta gtccgttaca
    24481 agggcagata gttacaaaag gggctggtag gaagatagac gggataacta tctattcatt
    24541 attggattat gggtatggaa cagcagcagg atgtttagga atccattgtg gtcattatct
    24601 gacaccgttt attgttggag ttcatgagtt accgaactta ccagactacc tgaagaatct
    24661 aacaccagaa caagctgaag aaaatgcacg cattgaagca ggtcaaagag gccttgagag
    24721 acttatcaag acacataaag agcggttgca ttacgctcat accttgcaag atgacaagat
    24781 gatacaagct gagcgtttga aagttagagg gtatcaaact aagatccgta acttgataaa
    24841 tcagcatgat ttcttaacaa gagattacag acgagagaaa ttatatattt cataaaggat
    24901 ttgtgtttca caagtccttt tttgtgttta aaaccgtaaa aaatccctat ccatcaaagg
    24961 tatattgaga gagtaaataa tattttgctt taggtgggag ttatccacct aaaaaagaac
    25021 taggagggta caaatggcat ttacaactga agaactactc aatcttgggt tgacagaaga
    25081 acaggctaag tcagtctttg ctttgcgagg aaaagagctg aatgaggaca aatcagcctt
    25141 agaaactatc aaacaagagc gagatagtct caaatcacag ttgcaaaaag cagaggagca
    25201 agttgaacac ttgaaatcgc ttgagaatat cagcgctgaa caaaaagatg cgattgataa
    25261 attgcaagct gaatatgaca agtataaaaa cgaagctgca gctgaacttg cacagacaaa
    25321 aaaggttagt gctatcagtc tagctctgaa agatacaaat gctttcaatc cagacaaatt
    25381 gatgaaattc attgatgttg atgctatcca gttagacgac aacgggaaac ctcagattga
    25441 tgaagtaatc aacggtttaa aagaaagtga tccatatctg ttcaaagctg aagaaagtaa
    25501 gcctagcccc aatattttac ctcaaggtaa tccggcagga gagggtacaa gtgatgttga
    25561 tccgttccaa gcgattattg acgggtatgg caaataacag aaaggagatt acaaatgcca
    25621 agtaatcaaa acaacgcagt gcgccgctat gagaaacaat atgcgggcat tcttgagaca
    25681 gtttttagag tgcgggcagc attttcaaac gctctagcat ctattcagat tttggatggg
    25741 gtacaagaaa actctaaggc tttctcagtt aaaacaaaca acacaccagt tgtaatcggt
    25801 gagtacaaaa ccggtgaaaa tgatggtgat tttggtgata actcaggggc tcagtcacgc
    25861 tttggtggtt tgacagaagt taaatatgaa aatacagatg tcaactatga ctataccctt
    25921 acaatccatg aggggcttga ccgttacaca gtaaacaatg atcttaacgc tgctgttgcc
    25981 gaccgtttga agttgcaatc cgaggcacaa actcgaacag tgaacaagcg aattggtaaa
    26041 tacttgtctg acaacgctac taatacggaa gcccttgctg attttacaga tgacaaagta
    26101 aaagctttat tcaataagtt gtcggctttt tacacaaaca acgaagttac agcgccgatt
    26161 actgtttact tgcgttctga attttacaac gccatcgtag atatggcatc agttacaagc
    26221 gccaaagggg caactatctc ccttgatgaa aacgggctac caaaatataa gggctttacc
    26281 ttggaagaaa cgccagcgca gtactttgag acaggagtta tcgctatctt ctcaccaaac
    26341 ggtattgtca ttccgtttgt tggtatctca acagcccgtg taattgaggc tgaaaacttt
    26401 gatggtgtga aattgcaagc tgctgctaag ggtggtactt acactcttga tgacaataag
    26461 aaagcaattt acaaagttac aggaactatt gtataggagg tagaacatgg caatttacaa
    26521 agcaacaaaa aatcttttct ttgagcaact caacatggat gtgattgtca atgacattat
    26581 tgaacttgat gaagattatg ctaaagaagt caacaagaaa ctaaaaaatg cttttccaga
    26641 tgtgaaaaat gttttagaac ttgttgacaa aaatggaacg cttgaaccag aagatgcccc
    26701 atctgtagat gatgcatctc aggcaactgt tgaagattaa ataaggggtg gcaacaccct
    26761 ttatttttaa gggaggttac acatgactta tttgacacaa gaggagttcg atgagttaga
    26821 ttttgatgaa gttacagact ttgaaaaatt ggcaaaacgg gcaaagatag cgattgacct
    26881 atacactaac ggtatttatc agaaagacat tgattttgaa aaagaaattg cctatcgcaa
    26941 atctgctgta aagcttgcta tggcattcca aatagcctat ctcgatgcct ctggtattat
    27001 gtcagccgat gacaaacagc tagccaatag tgtctctatt ggccgtacat caatctctta
    27061 tagcacctca caaagcacat tagcaggtca gcgatttaat ttgtctatgg atgctgaaaa
    27121 tgctttgaga caagccggct ttagcctagt tgttggagtt gcctatgatc gataagcggt
    27181 tattaaaagg gattgacaag cgtttgttaa aggatgtgct aaccataaaa aaagtagctg
    27241 ataaaaacga ttatggggat gaagtatatt cagaaccgtt gactattaaa aatgtacgtt
    27301 ttgatagatc agtgggggga tctggtaatc gtaattcaaa aactggtaca ggaaattcaa
    27361 aatcaaggca aaaacaaggg gttatatacc tctatccctc gctatctttt gtgacagttg
    27421 ataacagttg gatgggtgca aaagtaaacg atgggatagg agattacaca attaatggat
    27481 ttcaaactaa ctattatgat ggtgagatat tcagtcaaga aattgaggtg atctaatgaa
    27541 tatcgccatt aaagttgact tgcagaaagc taaacagaaa ctttcgaacg aatccatgac
    27601 aagaggaaag attgcagtcg ctagcaaaat cttgctagac aatgagcaat atatcccctt
    27661 gaggggtgga gagttgagag cttctggccg aatcgttgga caaggtgatg ctgttgtcta
    27721 tggaacagtt tatgctagag cgcaatttta cggagcaaac ggcattgtca cctttaggag
    27781 atataccact ccaggtacag gaaaacgatg ggatcaagtt gctactagta aacatgctga
    27841 agaatgggct agagcttttg tgaaaggaat ggggctttga tgcgagagaa tgactttcaa
    27901 aatgtacttt taaagcatat caagacttta aatttaccag ttgaaccacg ctttgattac
    27961 tttgaggatg acaaagatga tctggttatc aatcagatac caggcgggaa agtggataga
    28021 gagtatatgg atggcacaca agaagtttct ttgccgtttg aaatcgccgt aaaggcaaaa
    28081 aagaactcag tagccaatga cactatttgg ttagtcacct cagaactagc aaagatagac
    28141 ttagttttac caagtgacaa taattcttat gaatatatgg gaatggaagt cagcaggcct
    28201 gccatgaaag gcaaggatga gcaaggctat tattattaca caattgaaat tgtggcgaaa
    28261 atcgtaatag agaggaacaa acaatgacaa gacaaaaaaa cgccctacgt ggccattttg
    28321 tagctccata caatggagga actgaaccaa caacagaaga tacatggttg gaacttgcta
    28381 aatggatctc agacgtatca gatgatacag acgagaaaac agatgatcaa gcatactatg
    28441 acggtgatgg agttgaagaa acaaccgtgg tcagcgtaaa aggtgcttat acctttgagg
    28501 gtacttacga cccagacgat aaggcacagg ctcttattgc tgggatgaag tacaagacag
    28561 gggatgaccg taagctatgg cacaaggttg tttcttctga caagaagaaa caatgggtgg
    28621 gagctgcaac tgcaacagaa atcaaagcag gttctggtgc tgcctctgac tatgaggtgt
    28681 ttggatgtaa gctttcttac aactcaacgc caaaagagac tggtattggg taatagcttt
    28741 tgataagggc gggcattgag ccttgccctt tttaacaaca ggaaaaggag taaagacatg
    28801 acagatattc agattgaact aaaacgtaca ggatttccag taaaaatcgg agaagtagag
    28861 ctatggtttg atacaagtca agagagctta atgcgctttt atgacatgga agaagaacta
    28921 aaacgtcgcc ttgtccaata tgaattagat gtggtatctg caaatatcaa taacaaaatt
    28981 gagcgtgatg gagtaactaa agaagtagtt gctggggcta ttgaattgga gaagaaacag
    29041 cttgagattc aatatgatct tatttttggc gacggtacat ttgacaagtt atattctgta
    29101 tatccagatt ataacgccct aaataacgct ctagaacaga ccgcaatcat gttgcatgac
    29161 aagttggaag aacttgctga gcaacacaaa acggtggtga aagagcgtgc tagtcactat
    29221 ttaaacaagg gaaaagtcac tccaatcaag aacaacaaga aacaaaaaaa gaacaaaaag
    29281 aaatagcagg taaaaaatat gtctatgaaa ttaaatgatg ccttaatcac aaatttttct
    29341 attgctgata aagagtacga catagacctg tcttttaata aagttctaga tgtctttgaa
    29401 atcctaaaag aggatgaaat gacgcgtcta gaacaagctc agttgattgt ccatttgcta
    29461 actggccaag aattatacga catcaaagag gttgtagatt gttggattta cataaaagaa
    29521 cactttctag ggatcgaaaa agaaactgtt cagtatgatt tgctaggcaa tcccatgcca
    29581 aaggcaaaag gtgaagaaga acaagaaaaa ttgattgatt ttgaacaaga tgcagagtac
    29641 atttacgcta gttttttaca agcctacggc atcaatcttt tgaaagttca aaatgagttg
    29701 acatggacag aatttaaagc acttttgaac gctttgccag ataacacaat catgcaacag
    29761 attatagaaa tccgagcatg gaaaccagaa tatggtgggg ataagaataa aatgcgtaaa
    29821 ttacaagcta aatatagttt aggaaaggag ggagaagata atgactgatg gaaaagtgac
    29881 catcgttgtc gatgtggatg gtaataaagt caaggttcta aacgatgagt tagataaaac
    29941 ggcacagaaa ggtgacagag ggagcgattc tctaaagaag tttgcgattg gtggtgctgc
    30001 ttttaaactg gcatctaaag cggtagatct tctaacagat tccttgggcg gagcgattca
    30061 acgttttgat actcttgaaa gttatccaag agtgatgcaa gcgatggggc atagtacaga
    30121 agatgtcacg cgctcaacta agaaactagc ggcaggtatt gagggtttgc ctacgacttt
    30181 aaatgaagtg gtaggcacag ctcaacgcct tacctcgatt actggcgata taaacaaatc
    30241 aacagattta acacttgctc ttaataatgc ctttcttgcc tctggatctt ctagtgctga
    30301 tgcaagccgt ggtttacaac agttcagtca gatgttatca gctggtaagg ttgacatgca
    30361 aagttggaaa acgttacagg aaaccatgcc ttatgctttg caaaagactg ctgaatcatt
    30421 cggttttgct ggccaatctg ctcagaatga tttctattct gcattaaaag aagggcgtat
    30481 cactttcaac caattttcaa gcaaattggt tgaattgaat ggtggcgttg gtggttttgc
    30541 agaacttgct aaaactaaca gtaaagggat ccagacatct tttgggaact taaagaatgc
    30601 ggttgttaaa ggtgtagcta atactatcaa ggctcttgac gatttaacaa aggcagcaac
    30661 aggtaagacg attgctgaga acttcgatgc attgaaagta atcatcaatg cggcttttgg
    30721 tgttattgtc aacgtaatta aagctagcac acctgttttt cagactttgt ttagtatttt
    30781 gggtattgga gcttctgtaa tctcattttt gagaccggct attatcggtt tagttgctgc
    30841 tttggtaact atgcgtgcca tcaatcaagc ggtaaaaacg actaaggact tgataagcgc
    30901 gtggaaaata ttcaaactaa cagccacaag agcgattcgg atcatcaatc tactgacagc
    30961 tgcccaagct acttatggct caataacaaa ggctcaactg gttgctcact tggccaataa
    31021 cggagctttg acagcatcca atttgcttta tggggttcta actggctcta tcagcttaca
    31081 gactgctgct actattgctg cgactgctgc aactaccgca tttaaagcag gactgaccgc
    31141 agttaaagca gcgctgaccg ctttaactgg cccgattggt ttggttgttg ctggtgtagg
    31201 tcttgctgtt ggggcattgg tagggttgtg gcaatggcta actgccgaga gtgaggagac
    31261 caaacgcctc aaatcagaac aagaggagtt agtcaagagt acggatcaat taacggattc
    31321 tgttaaacaa agcgcaaaag aacgtcaaaa aaatcttgag tctgtaaaag gtaatacaga
    31381 atcttaccaa aaattggctg acgaaattgt ccagttatca caaaagacaa ataagacagc
    31441 agcagacaag aaaaatctca agaaaaagat tgatgcttta aatgcctctg ttagtggtct
    31501 aaatctagct tatgataaga actcagattc tttgtcacac aatagcgatg aaatcaaagc
    31561 tagaatctca gctatggagg cggaatcaac atgggagaca tcccagaaga acctgcttga
    31621 tatcgaacaa aagcgcgctg aaattggcga gcaactgaag cagatagctg aacaacgcaa
    31681 aaaatggaat gaagaatcca atgttagcga tggtgtccgc aaagaaagac tgcaagaact
    31741 caacgacaag gaaactgagc taaaaaatac tcagacagaa ttgcaaactg agtacgaaaa
    31801 aacgtctcaa gttcaacagg cggcatctga agcgatggct gctgctgccg aaaatggttc
    31861 aaatagacaa gttgtagcat acgaaaatat gtctaaatct caacaaaaag caatagacga
    31921 tatgcgtact aagtacaatg aattacttga gacaactacg aacatgtttg aacaaatcaa
    31981 gtataagtct gctattagtg tcgatgaaat gattgccaac ctccaaaaaa accaagaggc
    32041 ggttaataat tgggcaacaa acctcaatac attggccgaa cgtggggtaa acgaggggat
    32101 tttagctaaa ttacaagcga tggggcctca aggtgggttg tacgttcaag aactcgttaa
    32161 tgcatcagac gaaaaattgg caacattgaa cgaagtcttt actcaaggtg gtgagtcagc
    32221 tatgaatggc ttaactgctg gtatggatac gggtgctttg ggtatcacag acaaaatcaa
    32281 gggtattgta caaagtcaag tttcaagctt acaagaggaa attgcagctg ctgacttttc
    32341 tagtttgggg caagaaatcc ccaacggggt cagtcaaggg atagaacaag gagcttctac
    32401 tgccggagaa tcttctaaaa acatggctaa tgatataaaa gaatccttta cgagcgaaat
    32461 ggatattaat tccccatctc gtgttttcaa tgagtatggt ggttttatca ctactggttt
    32521 agctgagggg gtagataaag gtaccaatca acctgtatca tctgttacta atttagccaa
    32581 tcaaattaag aaaccatttg atagtctgca gagtgatttc acgtacattg gtgaaatggc
    32641 gatgtctggt cttaatgcag ggctttggag tggctctggt tctgttatgg caacagctaa
    32701 ttcaattgct gaaagggtaa aagcgaccat caagagcgca ttagatattc actcgccatc
    32761 tagagcaatg cgtgatgaag tcggacgttt cattcctcaa ggtatcgctg ttggtattga
    32821 agcagatgca ggggttgttg aaaaatcaat gttgcgatta aaagaaagca tgatgattga
    32881 tactagacca gaaattgcac ttggcttaaa caagaaacta ggtgctcaag tgactgttaa
    32941 acaaagtagt aagcagacaa tagctgaaaa aatcaaagtt actatggaca agtctagcga
    33001 actactcaaa aaagccctgg atgtagctga gacggccgtt agacgaccaa atgaaatgta
    33061 cttaaacgat ggtactttag tcgccagaac aggcgataaa tttgctaaat atcaatcgga
    33121 acaactaaga cgagataata ggatgaaagg ggtattgtca tgacaaagat aatgactttc
    33181 aacggagttg atatgtctaa attctttcgt ataacagata ttatccgccc tatcgggaac
    33241 aagaggagcg tatcaactga taacgctccc ttattgggcg tgaatatcca acaggttaag
    33301 attggagaaa aagagcatat cataaaattt gacatcaaaa ccacaaatgc aattgaaatg
    33361 gaacaattaa agcatgattt ggcaggcatt ctaaacgttt tagagccagt aaagattact
    33421 tatggcgatg agccagacaa atactatatg gggttgccgg tagatgagat tactccagaa
    33481 aatttgacaa gatggttcca gcgctcagag ttaaaaataa taattcctga tggcgtggct
    33541 cacagcacga ctttaaaaaa ttttgatatc gatacaaatg aaacaagcgc accggatagg
    33601 atagtattta atttaacaaa tacaggaaca gagccagctt atccaattat tagaattaaa
    33661 cacaactcag agaatggata tattggagtt gttaacaaca gagcggcgtt tgagttagga
    33721 aatcgtgaag aggctgatac tgaaaaatac agagactctg aaacattgat agattataga
    33781 gggactaata ttctaaaagg atttcaaaat ggcactaaag gagtagctgt aacaaatgat
    33841 aataaggagc gtcttgttgg cactttgagt acaacaagta tgtgggggcg taatcatatc
    33901 gaattatcaa accgtggtac agttgaaaaa aatcgaaata atgcacaaag tttgacatgg
    33961 gctattcctg ttgatagtag tggagaagtt ggttcattga atgactacct gctttggaga
    34021 caagttttta tggcagctgt cgctaatcaa tatggtttca taaaggttac tgtatcggat
    34081 acagacggca atttcttgta tggggtggaa acttacaaac gctatcagac acttgattgt
    34141 gagtatagtt ttttcaccac tgacggcaaa ggtggataca agtttatcaa atggtggtat
    34201 tttactggga caggggctca agtaggcaaa cttgatccat ttagcgcgga aaagggctgg
    34261 tcagagttaa aaagaaacga tgatagagtt caagtgtttt ttgatggctc tcattatgac
    34321 tttattattc cggagataaa agacaaaaaa tcagcaaaaa tccatatcac gcttggagca
    34381 ctcagagact ggcctcttgt atcacatatg tatgttgatg agttcatgta tagaaaagac
    34441 tttgtgacaa agagtagaga tattcctaat cgctatccaa taggttcaaa tgttgtaatc
    34501 aacagtgagg acgatagtgt gtatattgac gggatatcta aagtaagcga agttgtagac
    34561 ggttcacatt ggccagcaat tcctccagga aaatctcaac tagagttgta tttttcacgt
    34621 tttgttaaga aaaaaccaac tgtaacaatc gaatttgaag aaaggtggat ataagatgct
    34681 tttgacaatc catgatgcaa atttacaaaa ggtagcattt attgataacg aaaaacaagg
    34741 tacgttaaat tattacgatg atacttggac aagaagtctt gcaacaggtt cgtcaacgtt
    34801 tgagtttacg gtatttaaaa aggctgtaaa gtctgattta cctcttgcta aagcctatca
    34861 tcatttgaat gagcatgcat ttgtctcatt taagtacaag ggtaaaagct ttgtgtttaa
    34921 tatcattatt gttgaagaaa atgagcagac aatcaaatgt tattgtgaaa atctcaatct
    34981 tgagttaatc aatgagcttg cgaaccctta taaatctaac aaagcgatga ctttcaaaga
    35041 gtattgtgag gcgatggatc ttttaaatta tactcacctt tctattggta tcaatgaaat
    35101 atcagattat aagcgtactc tggaatggga ggggcaagaa accaaactag cccgtctatt
    35161 aagcctagcc aaacgatttg atgctgagat tgaatttgat acacagttaa atgctgatag
    35221 cactatcaaa aagtttagtg ttaatgttta tcatgaaaac gatgacaacc atcaaggggt
    35281 gggacgtgta agaaatgatg tcattgttaa atacggaaaa aacatccact ctattacaag
    35341 aaaagtggat aagactggta ttttcaatac aatcagaccg actggtaaaa tgccaacggt
    35401 tgaagaagaa ccgagcggag ataagggctc caaaagcgaa actgtaaaaa atgcagatgg
    35461 ttcaacgacg aaaaccacaa tctctacagc ctcagatggg actaagagca aaactattgt
    35521 ccacactaaa gttacaaagt tagcggacaa gacacggatc acaacgacca caacgactcg
    35581 ttctgatggt tccatagaac aaactgttac aaccagcaaa aaaggcggag catcaacgtc
    35641 tgaaacaaaa gtcttgaaaa aaccaaatcc aaaagaaaaa acaaatacaa ctgaggatgt
    35701 tttgacgatt gagggattgg atgaatggga agtaaagaac gagaaaggga tagttgaatt
    35761 ttatcaaaga gggcaagcac tgtatgcgcc tatttcaatg caactatatc cctcaacctt
    35821 tactcattca acaggggagc ttgaccagtg gacaagaaaa gattttcatt ttgaaacaga
    35881 tgagccaaac gagttaagac gtttaggtta tctcaaattg aaaaagtatt gttatccagc
    35941 tatcacttat gaagttgatg gctttgtcga tgctgatatt ggagatactg ttaaagtcca
    36001 tgatgacggt tttgcccctc tattgatgat tcaagcacgg gttactgatc aaaaaatcag
    36061 tttcacaaat ccagtgagaa ataagacaat atttgacaat ttcaaggcac ttgaaaacaa
    36121 actatcagct gatatccagt cagcctttga gagattgttt gaagctgcta aaccatatac
    36181 tatcaaattg tcaacggaca atggtgttat ctttaaaaat cagatcggcc agagtctagt
    36241 aaccccaacc ttatacaagg gaggaaaacc agtcgttgtt ggtgttactt ggcgatgggc
    36301 acttgatgga gaagtaacaa cagggatgac ttacttagtt agaggctcaa atgtaactga
    36361 tacagttact ctgacagttg cagcttacat tggaaataaa gaggttgctg ttgatgagat
    36421 atcgcttgtt aatgttgctg atggaaaact tggtacacct ggaactccag ggcgagatgg
    36481 ccgtactcct tatgtccata cagcatgggc taataatgca acaggaacag atggatttag
    36541 tcttgatagc tcaatcaata aactctatat tggtatttat acagactttg aaccaaacga
    36601 tagcacagac cctaaaaaat acaagtgggc taaagtaaaa ggagaaaagg gagaaaaagg
    36661 agataaagga gaaccgggac aacgtggttt agatggcttg caaggtgcaa gaggtgaaca
    36721 aggattacct ggtcgcaatg gtgcagatgg ccgtactcaa tacactcaca tagcttacag
    36781 caatagcgct gatggaacta aggatttttc tgtaagcgcc tctgatagag cttatatcgg
    36841 tatgtatgtt gattttaata gagctgatag caatactcca tctgattaca attggacact
    36901 tgtaaaagga tctgatggcg caaacggtgt ggcaggtaag gctggtacag atggtaggac
    36961 accatactta cacatagctt acgccacatc aaataatggt tcacaaggtt tttcaactac
    37021 tgacagtaca aataaaacgt atatcggaac atacacagat tacactcagt cagatagtac
    37081 agattacaga gtgtataagt ggacgttgat aaaaggggca gatggtactg gtatttctaa
    37141 tgtaactaat tattatttag ctactacagt ctcaacaggt atcacaagaa caagcgcagg
    37201 gtggacaact acgccacagc ctatcacatc agacaagcgt tatttatgga attatcgagt
    37261 tgagctatac acaaacggta caagtaagac aacagagcct actgttattg gtgtgcacgg
    37321 ggataaagga gaacgtggat tacaaggttt acaaggcttg caaggcgcac gaggtgaaca
    37381 aggtattcct ggacctagag gggcagatgg ccgtacacaa tatactcaca tggcctatgc
    37441 cgataacgca acaggtggtg ga
//
LOCUS       DAVLDI010000015        36638 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLDI010000015 DAVLDI010000000
VERSION     DAVLDI010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36638
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.015"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            112..1890
                     /locus_tag="VXD01_000770"
     CDS             112..1890
                     /locus_tag="VXD01_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV0601201.1"
                     /translation="MSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIY
                     WNKKTNKYKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIG
                     RSAMVTKLLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYP
                     ELEPSKLGTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGK
                     TYLAKEIAKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKD
                     FCQKAKEPQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSG
                     VPGWSLPSKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKF
                     VFIIDEINRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIG
                     TMNDIDRSVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIEN
                     VQELNSHYHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAF
                     DLTNNEQKDQAVADDNEGDENDDADY"
     gene            1877..3193
                     /locus_tag="VXD01_000771"
     CDS             1877..3193
                     /locus_tag="VXD01_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV0601202.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNPLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRSHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIENQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            3368..4354
                     /locus_tag="VXD01_000772"
     CDS             3368..4354
                     /locus_tag="VXD01_000772"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV0601203.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            4418..4489
                     /locus_tag="VXD01_000773"
     tRNA            4418..4489
                     /locus_tag="VXD01_000773"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4451..4453,aa:Arg,seq:ccg)
     gene            4672..5370
                     /locus_tag="VXD01_000774"
     CDS             4672..5370
                     /locus_tag="VXD01_000774"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV0601204.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            5361..8900
                     /gene="smc"
                     /locus_tag="VXD01_000775"
     CDS             5361..8900
                     /gene="smc"
                     /locus_tag="VXD01_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV0601205.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAVLEDKRNS
                     LSQEKSDKESSLVLLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKASQQKDELETAKVQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAASAGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARKVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVTDIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELDNLNLAEQEVQDLEK
                     AIRSLGPVNLDAIDQYEEVHSRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            8897..9691
                     /locus_tag="VXD01_000776"
     CDS             8897..9691
                     /locus_tag="VXD01_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0601206.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            9691..10509
                     /locus_tag="VXD01_000777"
     CDS             9691..10509
                     /locus_tag="VXD01_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0601207.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKVAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            10513..11790
                     /gene="ftsY"
                     /locus_tag="VXD01_000778"
     CDS             10513..11790
                     /gene="ftsY"
                     /locus_tag="VXD01_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV0601208.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETVE
                     ENNSEILEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(11836..13323)
                     /locus_tag="VXD01_000779"
     CDS             complement(11836..13323)
                     /locus_tag="VXD01_000779"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV0601209.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(13472..14212)
                     /locus_tag="VXD01_000780"
     CDS             complement(13472..14212)
                     /locus_tag="VXD01_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0601210.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(14212..16377)
                     /locus_tag="VXD01_000781"
     CDS             complement(14212..16377)
                     /locus_tag="VXD01_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0601211.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            16550..17503
                     /locus_tag="VXD01_000782"
     CDS             16550..17503
                     /locus_tag="VXD01_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0601212.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            17580..19568
                     /gene="uvrB"
                     /locus_tag="VXD01_000783"
     CDS             17580..19568
                     /gene="uvrB"
                     /locus_tag="VXD01_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV0601213.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVVAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            19578..20141
                     /locus_tag="VXD01_000784"
     CDS             19578..20141
                     /locus_tag="VXD01_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0601214.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            20107..20616
                     /locus_tag="VXD01_000785"
     CDS             20107..20616
                     /locus_tag="VXD01_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0601215.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALDHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            20669..21136
                     /locus_tag="VXD01_000786"
     CDS             20669..21136
                     /locus_tag="VXD01_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0601216.1"
                     /translation="MSRSQLTILTTICLIEDLETQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMESPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(21133..21648)
                     /locus_tag="VXD01_000787"
     CDS             complement(21133..21648)
                     /locus_tag="VXD01_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV0601217.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(21660..22187)
                     /locus_tag="VXD01_000788"
     CDS             complement(21660..22187)
                     /locus_tag="VXD01_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0601218.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(22469..23032)
                     /locus_tag="VXD01_000789"
     CDS             complement(22469..23032)
                     /locus_tag="VXD01_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0601219.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILSLAIVPRLQTLKK"
     gene            complement(23016..23567)
                     /gene="coaC"
                     /locus_tag="VXD01_000790"
     CDS             complement(23016..23567)
                     /gene="coaC"
                     /locus_tag="VXD01_000790"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV0601220.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLSLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(23579..24268)
                     /gene="coaB"
                     /locus_tag="VXD01_000791"
     CDS             complement(23579..24268)
                     /gene="coaB"
                     /locus_tag="VXD01_000791"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV0601221.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPESHPNLSIREITNTKDLLIEMQERVQDYQILIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            24498..26168
                     /locus_tag="VXD01_000792"
     CDS             24498..26168
                     /locus_tag="VXD01_000792"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV0601222.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKLR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKSQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            26496..27671
                     /gene="mutY"
                     /locus_tag="VXD01_000793"
     CDS             26496..27671
                     /gene="mutY"
                     /locus_tag="VXD01_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV0601223.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            27726..28430
                     /locus_tag="VXD01_000794"
     CDS             27726..28430
                     /locus_tag="VXD01_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0601224.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            28423..29772
                     /gene="vicK"
                     /locus_tag="VXD01_000795"
     CDS             28423..29772
                     /gene="vicK"
                     /locus_tag="VXD01_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV0601225.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            29774..30583
                     /locus_tag="VXD01_000796"
     CDS             29774..30583
                     /locus_tag="VXD01_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0601226.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            30674..30916
                     /locus_tag="VXD01_000797"
     CDS             30674..30916
                     /locus_tag="VXD01_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV0601227.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            30918..31172
                     /locus_tag="VXD01_000798"
     CDS             30918..31172
                     /locus_tag="VXD01_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0601228.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQINVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            31219..31992
                     /locus_tag="VXD01_000799"
     CDS             31219..31992
                     /locus_tag="VXD01_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEV0601229.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENVFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIILVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLLGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLQDELSSPRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(32255..33241)
                     /locus_tag="VXD01_000800"
     CDS             complement(32255..33241)
                     /locus_tag="VXD01_000800"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV0601230.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            33435..35903
                     /gene="gyrA"
                     /locus_tag="VXD01_000801"
     CDS             33435..35903
                     /gene="gyrA"
                     /locus_tag="VXD01_000801"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV0601231.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            35903..>36638
                     /gene="srtA"
                     /locus_tag="VXD01_000802"
     CDS             35903..>36638
                     /gene="srtA"
                     /locus_tag="VXD01_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV0601232.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQ"
BASE COUNT        11267 a         6437 c         8159 g        10775 t
ORIGIN      
        1 tatagtctaa ataaagaaga gttattaaat aaggcaactg ttggtgaaaa gtttaatgat
       61 aaattaaaag aagagtttct ccaggaatgg cctttggata ggattttaac aatgtcaatc
      121 gatgaatatg taataggaaa gggacagcaa aataagtctt tatgctacgc tcttgagaag
      181 ggaaaataca aaaatctatt tcttggaatt tctggtggct cagcttcaaa atttggtatt
      241 tattggaata aaaaaacaaa caaatataaa gatcaagcta ataatgagat ttcagagttg
      301 gatcagcgat tttcaaaatt aaaatcagat ttgtatgaaa ttatcaaaga aggtattcgt
      361 tttaactttg aaaatcctat ttttgatatg aaaagatcaa caaatgaatt tattggtcgt
      421 tctgctatgg tgacaaaatt actttgtatc tatactgagg gagatccttt ctttggtgta
      481 aatattaata gtcagaaaga attttggaac cactttgttt ctcagacaaa tcaaggtgga
      541 ccttatctgc aaaatcataa aataattgaa ctggtgtcca aaacttatcc tgagttggag
      601 ccatcgaaat taggaactat gctttttgag tattctaagc tttttatgga aaataaggaa
      661 gacaatagta caatggattc atcaaacaat tttagtcatc aattaactca atctctatta
      721 aagtctccaa accttatcct tcgtggtgct cctggcacag gaaagactta tcttgctaaa
      781 gaaattgcca aagaattaac ggatggcaac gaagaccaaa tcggatttgt acaatttcac
      841 ccatcctatg attatacgga ttttgtagaa ggtttaagac cagtatcaaa tggggatgga
      901 gctattgagt ttaggctaca ggacggtatt tttaaagatt tttgtcagaa agcaaaagaa
      961 ccccaattga ttggaggaca agataatttt gatgaggctt gggattctta cttagaatat
     1021 ataaatgttg ctgaagaaaa agaatatata acaaaaacat cttacttatc tgttaatagt
     1081 agacaaaatt tgtcagtaaa ttatgatagt ggtgttccag gatggtcact acctagcaaa
     1141 tatgtttacg agttgtataa agataaaaat tataataagc aagaatacta caaaagtggt
     1201 ggaaaaactg tcctagaaac attgagaaag agatttggtt tgaaagacta tgtttcccca
     1261 acagaaattg atactgataa gaaattcgtc ttcatcatcg atgaaatcaa tcgtggggag
     1321 atttctaaga tttttggcga actctttttc tctatcgacc ctggctatcg tggtgaaaaa
     1381 ggaagtgttt ctacccaata tgcaaatcta cacgaaactg atgaaaagtt ctatatcccc
     1441 gaaaatgttt acatcatcgg aactatgaat gatattgatc gttcagtgga tacctttgat
     1501 tttgctatgc gtcgtcgttt tcgttttgtt gaagttactg ccgagggtca agttggcatg
     1561 ttggataaag agttgaatat ccatgcagaa gaagcaaaaa ttcgtctaag aaacttgaac
     1621 gctgctatcg aaaatgttca ggaattaaac agtcattatc atattggacc aagttatttt
     1681 cttaagttga aggatgtaga ttttgactat gaattactct ggtctgatta tattaagcct
     1741 ctcctagaag actacttgcg aggttcttat gatgaggttg aaactttgga aactttgaaa
     1801 aaagcatttg atctgacaaa taatgagcaa aaagatcagg cagtagctga tgacaatgaa
     1861 ggcgatgaaa acgatgatgc ggattactga taatcaacac aagattatta aagaaaaatt
     1921 tgttgaagaa tatcctaaac taagcaatcc tcttttagac agaaccttgg aaagtctatc
     1981 ccaagatgaa cgtattttca tttttccaaa tgatttgact catactcctg atttggataa
     2041 ggaccaaaag atttttgaaa cagtcaatca gaaaattaag acagggaacg tgattggttt
     2101 tcttggatat ggtcaggaaa gattaacgat ttcctcacga ttttctgatg agagtaatga
     2161 ccattttttg cattatctct taaacaaggt tcttcatatc aatctcacta gtttagatgt
     2221 tgctttgtct cgtgaagaga ggctttatca acttttgatg tatctcttcc ccaagtatct
     2281 acaagctgct attcgaaaag gtctttataa ggaatatcat cgattttctc ataacgacag
     2341 tcatgttaag ggagtgattg atgtaagaag ccatctcaag aaaaatcttc ctttcacggg
     2401 aaatattgcc tacacaacga gagagttcac ctatgataat cccctcatgc agttggtccg
     2461 tcacactatt gaatacattg agaatcagaa aagcattggt caaggggtac tagataatct
     2521 ctcaactagt cgtgaaaacg tatctgaaat cgtgcgtgta acgccctctt ataaactagc
     2581 tgatcgtgct aagattattc ggggaaatca atctaaacct atacgtcatg catactttca
     2641 cgagtacaga aacttacaag aactttgtct gatgatccta aaccaagaaa agcacggttt
     2701 agggtatcaa gatcaaaaaa tctatggtat tctctttgat gttgcctggc tttgggaaga
     2761 gtatgtttac accttgttgc caaaaggttt tgtacatccc agaaataagg ataagacgga
     2821 tggaatttca gtattttctg ttgggaaacg aaaagtatat ccagattttt atgacagaga
     2881 acgaaagatt gttctagatg caaaatataa aaaactggaa ttgactgaaa aaggaatcaa
     2941 ccgtgaggac ttattccagc tgatttccta ttcttatatt ttaaaagctg agaaggctgg
     3001 actgattttt cctagtatgg agcagtcagt aaatagtgaa ataggaaaag tagctggcta
     3061 tggagctcaa ttgaagaagt ggtctattcg aatccctcag aatgcctcat cctatagtgc
     3121 attttgtaaa atgatggaaa attcagaaga aaattttaaa gcgattattg atgaagaagt
     3181 ggggagaaaa taatttcccc tctttctttt atttttaaca caagcaaaac ccgaacgata
     3241 tattttaatt cataaaataa tttgacaaaa actgtacttt ggtttataat aaattaagga
     3301 aacgtcggaa aaggcgtagt gatgcgagag cataggtagg tcattacaaa agaaacgaga
     3361 catcgatatg ttaaatgaat ttccaatttt tgattacgaa gatattcaat tgattccaaa
     3421 taaatgtgtc attaaaagcc gtgcagaagc ggatacaagt gtcactttag gaaatcacac
     3481 ctttaaacta cctgttgtgc cagcgaatat gcagacgatt ttggatgaaa atgtagcaga
     3541 gcaactggct aaaggtggtt acttctacat tatgcaccgt tttgatgagg caggacgcat
     3601 tccttttatt aaacgaatgc acgatcaagg gctcattgct tccatatctg tcggtgttaa
     3661 ggactatgag tatgatttcg ttagacagct caagactgat gctcctgagt atatcactat
     3721 tgatattgct catggtcatg cggatagcgt gatttctatg attcaacaca tcaagaaaga
     3781 attgccagat acctttgtaa ttgctggaaa tgtgggaaca ccagaagctg tgcgtgaatt
     3841 ggaaaatgct ggtgcggatg ctactaaggt cggaatcggt cctggtaagg tttgtatcac
     3901 caaggttaag actggttttg gtacaggtgg ttggcagttg gctgctctac gctggtgtgc
     3961 caaggctgcg cgtaaaccga ttatcgctga tggaggaatt cgtactcacg gtgatattgc
     4021 caagtctatc cgcttcggtg ctagcatggt catgattggt tccctctttg caggacacat
     4081 tgaaagtcca gggaaaacga ttgaagtcga tggtgaacag ttcaaagaat attatggttc
     4141 agcctcacaa tatcaaaaag gtgcttacaa aaatgtggaa ggcaaacgta tcttgcttcc
     4201 tgctaaaggt catctgcaag acactttaac tgagatggaa caagaccttc aaagtgctat
     4261 ttcttatgca ggtggacgtc aggttgctga ccttaaacac gttgattatg tgatcgtgaa
     4321 aaactccatc tggaatgggg atgcttccca ctaagacggg gtctttgacc aaaaaacttg
     4381 ttattagagc aaatttctgt tataataaaa caagtttcca cccttagtgt aatggatatc
     4441 acgtaagatt ccggttcttg agatgggggt tcgattccct cagggtggat gtaaacatcc
     4501 taaaaagcct ttaatagggc ttttttcttt atcctgaccc aaatttgccg ctaaaactga
     4561 gaatctctgt ctaaagaatt cccaaatgct ttccagtccc gttttagagt gactcagggg
     4621 gctttttttg atataataaa aaggactatt atcagttaga aagaggttgg tatgaaagaa
     4681 ttacaaactg tactaaagaa tcattttgca atcgaatttg cagacaaaaa tttactggaa
     4741 actgccttta ctcatacgag ttatgccaat gagcaccgcc tcttaaaaat ttcacacaat
     4801 gaacgcttgg aatttttagg agacgctgtt ctacagttat tgatttcaga atatctatat
     4861 aaaaaatatc ctaaaaagcc tgaaggtgac ctatcaaaac tccgtgctat gattgtccgt
     4921 gaggagagtt tagctggttt tgcgcgtgat tgccagttta accagtttat caagttgggt
     4981 aaaggggaag aaaaatcagg tggtcgcaat cgtgacacca ttcttggtga tgcctttgaa
     5041 gcctttcttg gtgcccttct tttggataag gatgtggcca aggtcaagga atttatctat
     5101 caagtcatca ttcctaaggt tgaagcaggc gagtttgaga tgattacaga ctataaaacc
     5161 catctccaag agttgcttca ggtcaatggt gatgtggcta ttcgttatca ggtgatttct
     5221 gaaacagggc ctgctcatga taaggtcttt gatgtagaag ttcttgttga aggtaagagc
     5281 atcggtcaag gccaaggtcg ttctaagaaa ttagcagagc aggaagctgc caaaaatgcc
     5341 gttgagaagg ggctggattc atgtatttaa aggaaatcga aattcagggg ttcaagtctt
     5401 ttgctgataa gaccaaggtc gtttttgacc aaggtgtgac ggcagttgtt ggacccaatg
     5461 gatctggaaa gtccaatatt acagaaagtc tgcgttgggc tttgggggag tctagtgtca
     5521 agagtctccg tgggggcaag atgccggatg tcatctttgc tggaaccgaa agtcgcaaac
     5581 cgctcaatta tgcttctgta gttgtgactc tggataatca tgacggattt atcaaggatg
     5641 caggtcaaga aatcagggtg gaacgccata tctatcgtag tggagatagc gaatacaaga
     5701 ttgacggcaa gaaagtccgt ctgcgtgata ttcatgacct cttcttggat actggattgg
     5761 gacgagattc cttctctatt atttcccaag ggaaggttga ggagattttt aattccaagc
     5821 ctgaggaacg acgagctatt tttgaagaag ctgctggagt tttaaaatac aagactcgca
     5881 gaaaagaaac cgagagtaaa ctgcagcaaa ctcaggataa tctggaccgc ttagaggaca
     5941 ttatctacga gttggataat caaatcaagc ctcttgaaaa gcaagctgag aatgcccgta
     6001 agtttttaga cttggaagga caacgtaagg ctatttattt agatgttctg gttgctcaaa
     6061 tcaaggaaaa taaggctgaa ctagagtcga cagaagaaga gttggctcag gttcaagaac
     6121 tcttgatgag ttattaccaa aagcgtgaaa aattagaaga agaaaatcaa actcttaaaa
     6181 agcaacgcca agatttacag gctgaaatgg ccaaagacca aggcagtttg atggatttga
     6241 ccagtctgat tagtgattta gagagaaaat tagccctatc gaaattagaa tctgagcaag
     6301 tagccctgaa tcaacaggaa gcacaagctc gtttggctgt tttggaggat aagagaaatt
     6361 cactcagcca agaaaaatct gataaagaaa gctctttagt acttttagag gaaaatctag
     6421 tccaaaataa tcaaaaactc aatcgtttag aagctgaatt gctagctttt tcagatgatc
     6481 ctgatcagat gattgagctc ttacgtgaac gctttgtagc tcttttacaa gaagaagcgg
     6541 atgtctcaaa ccaactgacc cgcatcgaga atgagttgga aaatagtcgt cagctttctc
     6601 aaaaacaagc agatcaacta gaaaagctga aagagcaatt agctacagct aaagagaagg
     6661 ctagtcagca aaaagacgag cttgaaactg ccaaggtgca ggttcagaaa ttattggctg
     6721 actatcaagc tattgccaag gagcaagagg agcaaaaaac ttcctatcaa gctcaacaaa
     6781 gtcaactctt tgaccgtctg gatagtctta aaaacaagca ggctagagct caaagtttgg
     6841 aaaacatcct tagaaatcac agtaactttt atgcaggtgt aaagagtgtt ctccaagaaa
     6901 aagaccgcct tggtgggatt attggtgctg ttagtgagca tttgaccttt gatgtgcatt
     6961 atcaaactgc cttagagatt gccttagggg caagtagcca gcatatcatc gtagaagatg
     7021 aagagtcggc aaccaaggct attgacttcc ttaaacggaa cagagccggt cgtgcaacct
     7081 tccttccgtt gacgactatc aaggcgcgta cgatttctag tcagaaccaa gatgttatcg
     7141 ctgcaagtgc gggatttcta ggcatggcag atgagttggt gacattcgat acgagactgg
     7201 aagctatttt caagaacttg ctagctacga cagcgatttt tgataccgtt gagcatgcgc
     7261 gtgcagcagc gcgcaaagtt cgttatcagg ttcgtatggt gactttggac ggtacagagt
     7321 tgcgcacagg tggttcttac gcaggtggag ccaatcgtca gaataacagt attttcatca
     7381 agccagaact ggagcaatta caaaaagaaa ttgctgaaga agaagcaagt ttgcgttcag
     7441 atgaagtgag tttgaagaac ttgcaagatg agctagctag attgacagaa agattagaag
     7501 ccatcaaatc tcagggagag caggctcgta ttcaggagca aggcttgtcc ctcgcctatc
     7561 agcagaccag tcagcaagtt gaagagctag aaactctttg gaaactccaa gaagaggaat
     7621 taaatcgtct ttctgaggga gaatggcaag cggataagga aaaatgccaa gagcgcctta
     7681 ctacaatcac tagtgaaaag aataatctgg aagctgagat tgaagagatt aagtctaata
     7741 aaaacgccat ccaagaacgt tatcaaaact tgcaggaaga gctagctcaa gctcgtctac
     7801 ttaagacaga actgcaaggg caaaaacgtt atgaagtgac tgatattgaa cgcttaggta
     7861 aggaactaga taatcttgat attgagcaag aagaaattca gcgccttctt caagaaaagg
     7921 ttgacaatct tgagaaggtt gatacagaat tgctcagtca acaggcggaa gaatccaaaa
     7981 ctcagaaaac gaacctccaa caaggtttga ttcgcaaaca gtttgagttg gatgatatag
     8041 aaggtcagct ggatgatatt gctagtcatt tggatcaggc tcgccagcag aatgaggagt
     8101 ggattcgcaa gcaaacacgt gctgaagcca agaaagaaaa ggtcagcgag cgcttgcgcc
     8161 atctacaaag tcaattaaca gaccagtacc agattagcta tactgaagca ctagaaaaag
     8221 cgcatgagtt ggacaatctc aatctggcag agcaagaggt gcaggattta gagaaggcta
     8281 ttcgctcact gggtcctgtc aacttggatg ctattgacca gtacgaagaa gttcacagcc
     8341 gtctggattt cctcaatagc cagcgagatg acattttgtc agcgaaaaat ctgcttcttg
     8401 agactattac agagatgaat gatgaggtca aggaacgctt taaatcaacc tttgaagcta
     8461 tccgtgagtc ctttaaagtg accttcaagc agatgtttgg cggaggtcag gcagacttga
     8521 tattgactga gggcgacctt ttaacagctg gtgtggagat ttctgttcaa cctccaggta
     8581 agaaaatcca gtcgcttaac ctcatgagtg gtggtgaaaa agctctatcg gctcttgcct
     8641 tgcttttctc cattattcgt gtcaagacca ttccttttgt catcttggat gaggtggaag
     8701 ctgcgctgga tgaagccaat gttaaacgtt ttggggatta cctcaaccgc tttgacaagg
     8761 acagccagtt tatcgttgta acccaccgta agggaaccat ggcagcggct gattccatct
     8821 atggagtgac catgcaagaa tcgggtgttt caaagattgt ttcagttaag ttaaaagatt
     8881 tagaaagtat tgaaggatga caattaaact agtagcaacg gatatggacg gaaccttcct
     8941 agatgggaat ggacgctttg atatggatcg tctcaagtct ctcttggctt cctacaagga
     9001 aaaagggatt tactttgcgg tggcttcggg tcggggattt ctgtctctgg aaaaattatt
     9061 tgctggtgtt cgtgatgaca ttattttcat cgcggaaaat ggcagtttgg tagagtatca
     9121 aggtcaggac ttgtatgaag cgactatgtc tcgtgacttt tatctggcaa cttttgaaaa
     9181 gctgaaaacg tcaccttatg tagatatcaa taaactgctc ttgacgggta agaagggttc
     9241 atatgttcta gatacggttg atgagaccta tttgaaagtg agtcagcatt ataatgaaaa
     9301 tatccaaaaa gtagcgagtt tggaagatat cacagatgac attttcaaat ttacaaccaa
     9361 cttcacagaa gaaacgctag aagctggtga agcttgggtt aatgaacatg tccctggtgt
     9421 taaggccatg acaactggct ttgaatctat tgatattgtt ctggactatg tcgataaggg
     9481 tgtagctatt gttgaattag ctaaaaaact tggtatcaca atggatcagg tcatggcttt
     9541 tggagacaat cttaatgact tacatatgat gcaggttgtg ggacatcctg tagctcctga
     9601 aaatgcacga cctgaaattt tagaattagc aaagactgtg attggtcacc ataaggaacg
     9661 gtcggttata gcttatatgg agggcttata atggcagata taaaattgat tgcattggac
     9721 ttggacggga ccttgctgac tactgataaa aggctgacgg atcgtaccaa ggaaaccttg
     9781 aaagctgcgc gtgatcgtgg tatcaaggtc gtattgacaa ctggtcgtcc cttaaaagcc
     9841 atggatttct ttctccatga gttagggact gacggtcagg aagatgagta taccattact
     9901 tttaatggtg gattagttca gaaaaataca ggagaaatcc ttgataaaac agtcttttca
     9961 tatgatgatg tggcacgttt gtatgaagaa acagagaaat tatcactgcc tcttgatgcc
    10021 atctcagaag gaacagttta tcaaatccaa tcggaccaag aaagtcttta tgccaaattc
    10081 aatccagctt tgacctttgt tccagtggac tttgaagact tatctagtca aatgacctac
    10141 aacaaatgcg tgactgcctt tgctcaagaa cccttggatg cagccattca gaagatttct
    10201 ccagaattgt ttgaccaata tgaaatcttt aaatcacgtg aaatgttgct agaatggtca
    10261 ccaaagaatg ttcataaagc aacaggtttg gcaaaactaa tcagccatct tggaatcgac
    10321 caaagtcaag tgatggcttg tggtgacgag gccaatgacc tctctatgat tgaatgggca
    10381 ggtcttggtg ttgctatgca aaacgctgtt cctgaagtaa aggtagccgc aaatgtagtg
    10441 acgccgatga ccaacgatga ggaagctgtc gcctgggcta tcgaagaata tgtgctaaag
    10501 gagaactaag atatgggatt gtttgaccgt ctattcggaa aaaaagaaga acctaaaatc
    10561 gaagaagttg tgaaagaagc tctggaaaat cttgatttgt ctgaagatgt tgatcctacc
    10621 ttcacagaag ttgaggaagt ttctcaggaa gaagcagagg ttgaaattgt tgaacaagct
    10681 gtgttccaag aagaggaaat ccaagacaca gttgaagaaa gtctggattt agagccagtt
    10741 gtagaagttt ctcaaaaaga agtcgaagaa tttccacact cagaagaagg gaatactgag
    10801 tttttagaga ctgtagaaga aaataattct gaaattcttg aagcagaaag gcctcaaaca
    10861 gaagaaactg ttcaggaaaa gtatgaccgc agtcttaaga aaactcgcac aggtttcggt
    10921 gcccgcttga atgccttctt tgctaacttc cgctctgttg acgaagaatt tttcgaggaa
    10981 ctggaagaac tgttgattat gagtgatgtt ggtgtccaag tcgcttctaa cttaacggag
    11041 gaactacgtt acgaagccaa gcttgaaaat gccaagaaac ctgatgcact tcgtcgtgtc
    11101 atcattgaga aattggttga gctttatgaa aaggatggta gctacgatga aagcatccac
    11161 ttccaagata acttgacagt tatgctcttt gttggtgtga atggtgttgg gaaaacaact
    11221 tctatcggaa aactagccca ccgctacaaa caagctggta agaaggtcat gctggttgca
    11281 gcagatacct tccgtgcggg tgcagtagct cagctagctg aatggggccg acgagtagat
    11341 gttccagtag taactggacc tgaaaaagct gatccagcca gcgtggtctt tgatggtatg
    11401 gaacgtgccg tggctgaagg tatcgatatt ctcatgattg atactgctgg tcgtctgcaa
    11461 aataaggata accttatggc tgagttggaa aagattggtc gtattatcaa acgtgttgtg
    11521 ccagaagcac cacatgaaac cttcttggca cttgatgcat caacaggtca aaatgcccta
    11581 gtacaggcca aagaattttc gaaaatcaca cctttaacgg gaattgtttt gactaagatt
    11641 gatggaactg ctcgaggagg tgtggttcta gccattcgtg aagaactcaa tattcctgta
    11701 aaattgattg gttttggtga aaaaatcgat gatattggag agtttaactc agaaaacttt
    11761 atgaaaggtc tcttggaagg tttaatctaa tcagaagcaa aaatcctgca aggcataaac
    11821 ttgcaggaaa tttttttatt ctaagcgacc atcttgacga taggtgatat ctggttgcca
    11881 agtccatttg gcaccgaatt tttcaagtag gtcaaagctg gcttgaggtc ccatgcttcc
    11941 agctttatag tcatgaagtg gggcaccatt ttcagcccag agcttttcaa tacggtcaat
    12001 caacttccat gacgcacaaa cttcatccca gtggctaaag ttagttgagt tgttatttag
    12061 gacatcataa atcaattttt cgtatggttc tggagaagca ccagttgcag tcgcatctgt
    12121 acggtaatca agtgagttag gagccaagtt aaattcttct cctacttgct tcccatttag
    12181 gctaagagag aagccttctg ttggttgaat atagatggtc aaaatatttg gagcaagtgg
    12241 ttctccaaag atagaatcca tttgtttaaa gacgatgttg acatgggttc ctttttcagt
    12301 cagtcgttta cctgtacgga aaaagaaagg aacactacgg aatcgatcgc tgtctacaaa
    12361 gaaggcacca gatgtaaagg tttcagttgt tgattctgga ttcacatttg gctcgctacg
    12421 ataagagatg tatttcatgc catcaatctt accagagcgg tattgcccac gtataaagtg
    12481 ttctttgagt tcttcatcag ttggatgata gaggttttta aagaccttaa tcttttcagc
    12541 acgaatctcg tcttttgtga agcttgctgg tttgtccatg gcgaggagcg aaagaagttg
    12601 tagagtgtgg ttttggacca tgtcacggag ggcaccggat tggtcatagt agccaccacg
    12661 ttcttctaca cccaagcgct ccgcaaaggt aatttgaaca ttgtcgataa aatccttgtt
    12721 ccaaacgttt tcaaaaatca agtttgcaaa gcgaactgca aagatgcttt ggatcatttc
    12781 cttaccaaga taatggtcga tacggaaaat ttgttcttcg tcaaatgttg ctaggagttc
    12841 gtcattcaac ttgcttgcag ttgcgtaatc tgtaccaaat ggtttttcaa cgatcaagcg
    12901 ctcaaaacct ttgccatcga caatgttttc agatttgagg tgtttggcaa tggttccaaa
    12961 gaactgaggt gccatagaca agaagaagag cttattgtgt tcagcttggt atttttcatt
    13021 aagctcagct tgtaattgac gcaaagcaat ataatgttcc gaatcattga catcatggct
    13081 ttgatagtag aagtggctag caaattcttg ggcttgctcg gtactatctg ccaaatcaag
    13141 gatggactcg acaactacag attcaaaata ttccttactc caaggtctac gggcagttcc
    13201 aataacggca aagtgcttgg aaagattgcc ggatttatat agtctaaaaa gggaagggta
    13261 gagcttgcgt ttagccaggt ctccactcgc accgaaaatt gtaacaataa ccttagatga
    13321 catctagcta cctaatttct atttttattc ctagtcttgc taggtatgag gaaacctcat
    13381 ttcataaact taattctaac ataattttcc gaaaaatcaa aaattccaat acgaggtaga
    13441 aaaactgcaa ggaaatcctt acagtttgag tttagacgtt taagacctta tctaagaact
    13501 ctttcagacg agggtgttgt gggttatcaa agatttggtc aggtgttccg tcttcaagga
    13561 actcgccatc tgcagtaaag ataacgcggt tggcaacctg acgagcaaat cccatctcat
    13621 gggttacgat aatcatggtc atgccttgct cagccaattc cttcataacg ttaagtacgt
    13681 ctccaaccat ctcagggtca agggcagaag ttggttcatc gaagagcatg atgtctggat
    13741 tcattgctag gccacgagct atggccacac gttgtttttg accacctgat aggctatctg
    13801 gattggcatt agctttatct gctagtccaa ccttttcaag caactccatt cccaatttct
    13861 cagcttcttc cttagtcatc aacttgtgct caataggagc aaaggtgatg ttgtccaata
    13921 cagacatatg agggaagagg ttgaagtgtt ggaataccat gccgatattt tcacggacgt
    13981 ggtcaacatt ggttgttttt tcagttaaat catagccgtt cacagtgatg tgaccgctag
    14041 tgacttcttc taaaagattg aggctacgga ggaaagttga cttaccagaa cctgaaggac
    14101 cgatgataca aacaacatct ccttcataga acttagtcgt aattcctttt aggacttcat
    14161 tttttccata gtgcttgtgt aaatcattta catcaatttt taattttgcc attaacgaat
    14221 cctcttttct aagcgtttcg ctagtctagt caaaagtgtg ataattacaa gatagaagat
    14281 agcaaggatt gcatacatct tgaaactttg gtagttacga gcaatgataa tcttaccagt
    14341 ttggaagagt tcaaccaaac cgatagcaga tacgatagtt gtatctttaa gagcgataac
    14401 gaattggttg acaaagtttg gcaacatcaa tttagttgct tgtggcaaga taatcttacg
    14461 catggttttt ccataagaga tacccaagct tcggctggct tccatttggc caactggaac
    14521 ggcctgaata ccaccacgaa cgatttcagc gatataagca gccgcattga gtgagagggc
    14581 aatggttcca gctacaaagt cgttaattgg gctttgttgg cctgtgatag actcgatgaa
    14641 gtttggaatt ccccagaaga tgaaggctgc aagaatcatc aatggaatac cacgaataac
    14701 gtcaacgaaa atctcagaga tgacgcgaag agatttgtat gggctaacgc taaacatacc
    14761 gaagataatt ccgatgacaa tggcaatagc aaatgagata agagctagag caagagtgat
    14821 accaagaccg ctaaggagtt gtttgtagtt gttttgaagc aagccccaga gcgttgtttc
    14881 gtcaacagta cttgttgaag cagttgaaga ttcgctagct aggtatttgt caagaatctt
    14941 ttggaattca ccgtttgctt taaggtttgc aagtccgttg ttgaacattt caatcagttc
    15001 tggatttgct ccttttttaa cggcaaaggc tgtttcaccg attggagttc cagagattgg
    15061 agttttcaat ttttgacctt ggctgataga atatttgaga acaggttcat catccataac
    15121 ggcatcaatg gcaccagtgt ttaaactgtc atacattgaa gaaccatcag caaaggtttt
    15181 gattttgtag ccgtatttgc tttgattttc tgttaggaag gtttgagaag cagttccgtt
    15241 tttaacaccg actgtctttc cttttagatc ttcataagaa gcaatattgc ttgattcttt
    15301 gacaccaaga atggtattag cagtgtagta tgattctgag aagtcaaaag ttgccttacg
    15361 agcatctgtg acagacatac cagcgatgat accatcggct tgaccagctt ggacagcact
    15421 gatagcagca tcaaaaccag ggttggtgat ttcaatttca aaaccttggt ctttagcgat
    15481 tgccttaatc aattccatat caataccagt gtattggttg cttgaatttt ggaaaacaaa
    15541 aggtgcaaaa gaagaatcgc tggcaatgat atatttagcc ttaacaggaa tagcttttaa
    15601 tcctgcgaga gtagttgtag ttggcactgc tgaagatgat gaagcagtcc atttcttgat
    15661 aattttatca agactaccat cttttttcat ttcagacaag gcttggttaa attcagtaac
    15721 taggtgctcg tatttacttc cttttttcac accgaaagca aaacttccta cagcttcacc
    15781 atccatttca atatggaggt cttgaccttg gttaatggca tattcgataa caggtttgtc
    15841 atccatcatg gcatcgatgg caccagcact caagctgttg ttcattaaat caccagtgtc
    15901 aaatgtttta atagtaaagc cgtatttatc tttgattgtt tcaaggaaac gttgagcggc
    15961 agttccgttt ttaacaccaa cggttttgcc agttaattgg tcgtacttgc taattttgtg
    16021 tgactttgta gtagcaatga caacttttgt atcatagtaa gtatcagaca tggtgaagac
    16081 tttttcacgt tctttagtct ttgtcatccc tgccatgata gcgtcggctt gcccagcttg
    16141 aaccgcattg actgctgcgt caaatccagg ataggacatc tgaatgttcc agcctttaat
    16201 ctcagcgact ttgttaataa tgtcaacatc aattccttta taagtttgat ctgaatcttt
    16261 aaactcaaaa ggtgcatagg cggtatcaga aacaatctta atcgtttctg ctttggcaat
    16321 acctaatgag aaaattggga ataaaattag caaaaatgct agaaattttt tcttcatttt
    16381 tagtctcctt ttccgaatat tctctcatta tatcagaaaa agtaaaaaaa ggcaaatttt
    16441 tatatttttc gtgtcagaaa atataacatt gatttttcct tttctttctt gaattgctat
    16501 taaaaagtgc tataataata gtatatatag aagaaaagag gacggggata tgaagaacaa
    16561 aagaatattt aaagacttcc aagcttcaaa aatgagttta aacatttaca caagcccctt
    16621 gttagccttt gtttttgtct tcataggaga gtttgtggct tttactttgt atggtattgg
    16681 cttgttagct ctcatcggac ttgctagaaa ttttggagag gctggtcaaa atcttgcaag
    16741 ctacttgcag accttgcatc agagcttgac ggataaaaca agtgactttc gtttaatttt
    16801 aggattactg gcctttggtt ttattcttaa cactgtgttc agatggacaa gaaaagttga
    16861 gaaaagacct attcgaacct tgggatttta tagagagaat ttcctcagca atcttctgaa
    16921 aggatttagt ctaggcttgg cactttttct tctgaccttg ttaggtttag tggtcttagg
    16981 tcaatatcgt ttggaatcca ttcacttgaa tccttattct cttgcctttg tcgtctttac
    17041 tatcccattt tggattttac aggggacagc agaagaagtg gtggcccgtg cttggctact
    17101 tcctcaattg gcctcaagaa ccaatctaaa actagctatt cttatatcta gcctgttctt
    17161 taccctgctt catatgggca attctggcct cacccctcta tctctagtaa atctcttttt
    17221 attcggagtt gccatggctc tttatcttct caaaactgat acagtttggg gtgttgcagg
    17281 tattcatggt gcttggaatt ttgctcaggg taatctcttt gggattttag ttagtggtca
    17341 accgtcagga acgtctctga tgaccttttt accacaaggc aatcaagatt ggctatcagg
    17401 tggttctttt ggcatagaag gttccattat gacaagtctg gtattactac tgctgattgt
    17461 ctatcttgct aataaattaa agaaagaaaa tgaaaggatg tgacttcggt ccgtcctttt
    17521 cttcgtgaaa atactataag tatgctaaaa taggaatagc acatggagag aggattctta
    17581 tgatcaatca cattacagat aatcaattta aactagtatc aaaatatcaa ccatcaggag
    17641 atcaacccca agctatcgag cagttggtgg ataacattga ggggggagaa aaagctcaga
    17701 ttctgatggg ggcgactgga acagggaaga cctatactat gagtcaggtc atttctaaag
    17761 tcaataaacc aactctggtt gttgcccaca ataaaactct ggctggtcag ctctatgggg
    17821 agtttaagga atttttccct gaaaatgcag ttgagtattt cgtatcctac tatgattatt
    17881 accagccaga ggcctatgtc ccttctagcg atacctatat tgagaaggat agttctgtca
    17941 atgacgagat tgacaagctt cgccactcag ctacctcagc ccttttggag cgtaatgatg
    18001 ttattgtcgt ggcctcagtc tcttgtatct atggtttggg ttcgcccaag gaatacgctg
    18061 atagtgtcgt tagtctccgt cctggtctag agatttctcg tgataaactc ttgaatgact
    18121 tggtcgatat tcagtttgaa cgtaatgata ttgatttcca acgcggaaga tttcgcgttc
    18181 gtggggatgt ggtagagatt ttcccagctt cccgagatga acatgccttt cgagtagaat
    18241 tttttggaga cgaaattgac cgtattcgtg aagttgaggc tctgacaggt caggtgttgg
    18301 gagaagtgga tcatttggcg attttcccag ctactcactt tgtgaccaat gacgaccata
    18361 tggaagttgc cgttgccaag attcaagcag aattagaaga gcagttagct gtctttgaga
    18421 aggaaggtaa attgcttgaa gcccagcgct tgaaacaacg gacagagtac gatatcgaaa
    18481 tgctgcgcga gatgggctat acaaatgggg ttgaaaatta ttctcgccac atggatggac
    18541 gtagtgaagg tgagcctcct tatacgcttc tcgacttctt cccagatgat tttttgatta
    18601 tgattgacga gagtcatatg actatgggac aaataaaagg catgtacaat ggagaccgtt
    18661 cgcgtaagga aatgctagta aattatggtt tccgtttacc gtctgccttg gacaatcgtc
    18721 ctctccgtcg tgaggagttt gaaagccatg tgcatcagat tgtttacgtt tcagcgacac
    18781 ctggtgacta tgaaaatgaa cagaccgaga cggtgattga gcaaatcatt cgaccgacag
    18841 ggcttttgga tcctgaggtg gaagtccgtc cgactatggg acagattgat gatctcttag
    18901 gtgaaatcaa tgcccgtgtt gaaaagaatg aacgaacctt tatcaccacc ttgaccaaga
    18961 aaatggcaga ggacttgacc gactatttca aggaaatggg catcaaggtc aagtacatgc
    19021 actcggatat caagaccttg gaacggacgg agattatccg tgacctgcgc ttgggtgtct
    19081 ttgatgtctt ggtcggaatt aacctgctcc gtgaaggaat tgacgttcct gaagtgagcc
    19141 tcgtagctat tctcgatgct gacaaggaag gtttccttcg caacgaacgt ggactcatcc
    19201 agactattgg acgtgctgct cgtaacagtg aaggccatgt catcatgtat gcagacacgg
    19261 ttacccagtc tatgcaacgt gctatcgatg aaactgcccg ccgtcggaaa attcagatgg
    19321 cctataatga agagcatggt atcgtaccac agacaatcaa gaaagaaatc cgtgacctga
    19381 ttgccgtgac caaggcagtt gctaaggaag aggacaagga agtcgacatc aatagcctca
    19441 acaaacaaga gcgcaaagaa ctcgtcaaga aactagaaaa acaaatgcaa gaagccgtcg
    19501 aagtgcttga ctttgaactg gcggctcaga tccgtgatat gatgttggaa gtcaaggcct
    19561 tggattaggg gaatagtatg atttatttaa gaaagttaaa gagagaagat ttgatgtctt
    19621 tatgggaaat ggcttattca caacttaatc cagtttggaa acagtatgat gctccctatt
    19681 atgatgatta tcagtatttt tcaaatttta aagaattcga actacaaaaa tcagaatcca
    19741 ttttaagcaa ctcaaatcgc cttggtattt ttgttgatga taaactagtt gggactgttt
    19801 cgcgttattg ggtatgtaaa caaacaagat ggatggaatt gggaattggt atttatgata
    19861 aaaaattctg gaacactggt attgggaaag ttgctatgtt gcagtggata gataggacgt
    19921 ttcaggatta cttggagttg gagcatctgg gtttgacaac ttggtcaggg aatcttggta
    19981 tgatgaaact tgctgaaaaa ttaagaatga aaaaagaagc tcatattcca aaagttcgtt
    20041 attatcaagg taaatatttt gatagtatta aatatggtat tttgagagaa gactgggaga
    20101 aaataaatga cggttattat caaatcaatg gaaactcctg aagagataga aggtaaatcc
    20161 ctcgttcact ggcaaacgtg gagagaggct tatgatgacc ttttgcctgc agaatttcag
    20221 gagacaatga cattagaaag atgtcgactc tttagtcaaa agtatccaga aaatacattg
    20281 attgcgatag gtgatctgaa ggtagttggt tttatcagtt atggtaactt tcgtgatgag
    20341 actattcaag ctggtgaaat tattgcttta tatgttttaa aagactatta cggaaaaggc
    20401 atagcacaaa agttaatgaa agcagctttg actgctcttg atcatttttc tgaaattttc
    20461 ttatgggtat tgaaagataa caagcgagcc attgctttct atcaaaaaat gggttttact
    20521 tttgatggac aagaaaagat acttgaactt ggaaagccta taaaggaaaa acgaatggta
    20581 ttctattcta aaataatttt aaaaagtaga agctaatggc actggtacca agtctgaaaa
    20641 tttaataaat tagaaagcga gtaaatttat gtcccgttcc caattaacga ttttaacaac
    20701 catttgtctg attgaagacc tcgaaacgca gcgcgtggtg atgcagtacc gcgctcctga
    20761 aaccaatcgc tggtctggtt atgcctttcc aggaggtcat gtagaaaatg gcgagtcttt
    20821 cgcggagtct gtcattcgtg aaatatatga agaaacaggg ttgactatcc aaaatcctca
    20881 acttgtcggc attaaaaatt ggccactaga tacaggtggg cgctatattg tcgtttgtta
    20941 taaggctact gagttctctg gtacccttcg ctcttcagat gaaggagaag tttcttgggt
    21001 gcaaaaagac cagattccaa acttagatct ggcctatgat atgctacctt tgatggagat
    21061 gatggaatct ccagacaaat ctgaattttt ctaccctcgc cgtacagaag atgattggga
    21121 gaagaaaatc ttctagtctt ttactaaata acctagctga tccaaggcct cctcgatata
    21181 gtggaggtct tgttgtgttt cggcttcgac taggtggtaa tggatgccat ctgtcaattc
    21241 agatagaggt ctaaagtcag aatgctcgac ttgttctaga aaatgttgca catctctgcg
    21301 acaagacagt ttaagcaagg tttcaatttc tccataaacg ggatggtcaa tcaaggtatt
    21361 ctggacatgc ccaccattat cgacaatagc aaggagttcc tgaccgattt cttcaacttc
    21421 atgtttcact ttgaaaagtt tgtgaacata aggattggta tcaatttgct tatagatgta
    21481 gccacgattg gtggatagga taggagcgcc atcggctctc aaaattgcaa tgtcctgcac
    21541 aatgacctga cgtgtgacat gaaaatgttc cgccaaactt tggccattaa gggctttagg
    21601 agcttctttc aagagttgga gcagggcttg tttgcgatct tttgtcatag cttttccttt
    21661 taacggcgtt ttcgaagcac tttatagaca gctagtgcta atgtatagtc taccatacta
    21721 tggataattg tgccaaatcc aactagtaca aatagaacat agaacatgtt ttctacattg
    21781 gtacccgaag ttgcgtaaaa aaggacacag gctaatactt cagcaagggc atgaacaaca
    21841 gccaaaacaa aattgaaaac ccaggaagat tttggtttat ctagggtatc ggggaatttt
    21901 tgtaggtaaa gagctcctaa agcaccaaaa gatatatggg aaaaggcccg aaaaacgata
    21961 accatgggat agccagccat caaaaatcca aaactagagg ctaggatgac aaaaactgcc
    22021 atcaagggcg acaagaacat ggctataaaa atagcgatgt ggctccccaa agtataggaa
    22081 gcaggtggaa tgacaatctt gaaaggcata acaattggaa tcaaaatcgc aatagccgtt
    22141 aaaagggctg tcattgtcat aaattgtgtc tttttccgtg tattcacaag aatctccttt
    22201 ttaactgcat atacactagt atggtacaat aaaccagaca ataaagcaag aatttacttg
    22261 ggtttataga tcatttttta gttaaaagtt atagtggatt gaaactagaa tagtacacct
    22321 ctacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttg tcctgttctt
    22381 atttcgtttt actatagtaa agatttcatt aaaaagaaac tgtatagagc aaaatctcca
    22441 ccttcaggtt tgaaagcgga gattgttttt attttttcaa ggtttgtagt cgtggaacaa
    22501 tggctaggga tagaattgca gaaatgacca attcagcaat tgaatttgtt gagataacgg
    22561 ttgccagaag aagttggata tttccattat aaacatttcc aaataggaag aagattcctc
    22621 caaggacaaa gatagtattt gtcaaggaac caagggcccc agctaaaatc agaccagtct
    22681 tgtttttcat cagtttatag actaagtaag gagttaaacc aatcaaaata cgtgggacaa
    22741 tggcaatgat agctgagtag atgtttccgt ttggtacgaa gggagagaag aggtagcttg
    22801 tcggtagaat cgtaatcgtg ttaaccgtca agctaagtaa tcccatcaaa aatccaagtg
    22861 taaccccaac tcgtggacca taaataatgc tggcaataat gacaggaata tgaacaatgg
    22921 tcggtttgat tggaaatgga aaaaggttaa agataagtga gctcagaaag tgtatcacga
    22981 gcatggtagc aaaaaagata gcaatgggtg caatattaga gcgttttttc atcgatagtt
    23041 tcctttattc tttctaaaat aattgtgagg tcagctaaag ctcctcgtcc gtggtctcca
    23101 caagctagta gggattcctt aggagcaatc agctgatagc cgtaggtttc taatgttttc
    23161 agattattct gagttactgg atggtcatac atttttgtat tcatagcagg agctattagt
    23221 ttgggaatat gacttggtag ggctagagct gtactggtta ccatgttgtc cgcaaagccg
    23281 tgagctagtt ttgcaatagt gttagcagtt gcaggtacca cgataaataa atctgctttt
    23341 tttccaagtt cgatatgatt gacctgatca ggatagggtt ccttcatgac atccaagtgg
    23401 acaggattct gtgagagtac ctgtagtgac aaaggttgga taaactctgt agcagcctga
    23461 gtcattaaga cagtgacttg atggccttgt ttttttagag aactgactaa atctgccgac
    23521 ttataagagg cgattgaacc cgttacagcc aagagaatgt ttgccatagt tttcctttct
    23581 aagaatgata ggcttgaatt ttttcaagga ggagttctgc aatttcttct ttagtctgga
    23641 ctgtttgaag ctgatttttc tcaacaaata tagctcggtg ctgatctgct gaaatttgag
    23701 tcaggtcatt cgcgatgatt aaatctgctt gattcttgat aagacttttt cgtgcaatat
    23761 caaccagatg atcttcggta acatcaacca gcagtttgaa accaatcaga tgaatagtag
    23821 gattccattc cttgactagg gatatgattt tgggtgtctt tttaaggaac aaaacctgaa
    23881 cctcatcagt tgaagaaatc ttggcctgat gattctgctt gcttaaaaat tcttttagat
    23941 tggagctagc ctgaacttcc tcaagccctg tcatataaac aggagtgtag tcagaaacag
    24001 ccattgagtg gatcaagatc tgataatcct gaacacgttc ttgcatttct attagaaggt
    24061 ccttggtatt ggtaatttct cgaatactta ggttaggatg agactctggc ttcagagctc
    24121 gttttgtcgt aattaaacaa acttcatgcc ctgcagaaag caaagtttct gtgataattt
    24181 tccccaagtg acctgtagaa tggttagtga tagagcggac gctatcgata gcttcactgg
    24241 taccgcccga tgtaactaaa attttcatag cactattgta cacaaaaata agcggtaagt
    24301 aaaatgaaag tgataaattt ttggtaaaaa cgaagattta ttatagtttc aaactataaa
    24361 gccatataaa atttaagaaa ggactctaaa agtcttaaaa acagagatat ttacgaacgt
    24421 ttagagagtt ttaggatgtt aaaaatcttg ttttgtgata taatgaatta tcatataaga
    24481 ggttagagga attttgaatg aaaacagata ttgaaatcgc acagagtatt gagttgaagc
    24541 caattgttga tgttgtagag aaacttggta tttcttacga cgatttggag ttgtacggaa
    24601 agtacaaggc taaactcagc tttgataaaa ttcgggcagt tgagagcaat ccagtcggta
    24661 aattgatctt ggttactgcc atcaacccaa cacctgcagg tgaaggaaag tcgacgctta
    24721 ccattggtct tgcggatgcc ttgaacaaga ttggcaagaa aaccatgatt gctatccgcg
    24781 aaccgtctct tggtccagtc atggggatca agggtggtgc tgctggtggt gggtatgcac
    24841 aagttctgcc aatggaagac atcaacctcc actttactgg agatatgcat gctattacaa
    24901 ctgccaacaa tgccctttct gccttgattg acaaccactt gcaccaaggg aatgagctgg
    24961 gaattgatca acgtcgtatc ctctggaaac gcgttgtgga cttgaacgac cgtgcgctcc
    25021 gccatgtgac tgttggtctt ggtggtcctc taaacggtat tccacgtgag gacggttttg
    25081 atattacagt tgcttcagaa atcatggcaa ttctttgctt ggcaacggac atcgaggact
    25141 tgaaacttcg tttggcgaat atcgttattg gttatcgcta tgaccgtacg cctgtttctg
    25201 taggtgattt gcaggttgag ggtgccttgg ctttgatttt gaaggatgct attaagccaa
    25261 acttggttca gacaatttac ggtacacctg cctttgtaca cggtggtcca tttgccaata
    25321 tcgctcatgg ctgtaactct gttttggcga cgacaacagc ccttcacttg gctgattaca
    25381 ctgttactga agctggtttt ggtgcggacc ttggtgctga gaaattcctt gatatcaaga
    25441 caccaaactt gccaacatct ccagatgcag ttgttattgt cgcaaccctt cgtgccctta
    25501 agatgaatgg tggtgtggct aaagacgctc tgactgaaga aaatgtagag gcagttcgtg
    25561 caggttttgc taacttgaaa cgccacgttg aaaatatccg taagttcggt attccagcag
    25621 ttgtagctat taacgaattt gtatctgata cagaagctga aattgcagtc ttaaaagaac
    25681 tctgtgcctc aatcgatgta ccagttgaat tggctagtgt ctgggctgat ggagcagaag
    25741 gtggagtagc acttgccgaa acagttgtta agacaattgc tgaaaatcca gctaactata
    25801 aacgtttgta tgataatgac ctttctgtcc aagaaaagat tgaaaaaatt gtcactgaaa
    25861 tctatcgtgg tagcaaagtg aactttgaga agaaatctca aacacaaatt gctcaaatcg
    25921 ttcaaaacgg ttgggacaaa ttgccaatct gtatggctaa aactcaatac agtttctcag
    25981 acaatccaaa tgcgcttgga gcaccagaaa actttgaaat taccattcgt gaattggtac
    26041 caaaattagg tgcaggcttc atcgttgcct taactggtga tgttatgacc atgccaggtc
    26101 ttccaaaacg tccagcagct ctcaacatgg atgttgaaag cgatggaact gtactaggct
    26161 tgttctagtg gattgaaatt gactttaagt gagtttggaa ataatatcca agctcatttt
    26221 ttctcagact gcaagcagtt catcaataag atttatactc ttcgaaaatc tcttcaaact
    26281 acgtcagctt caccttgccg taggtatatg atactgactc tgtcagttct atccacaacc
    26341 tcaaaacagt gttttgagca acctgcggct agcttcctag tttgctcttt gattttcatt
    26401 gagtataagt agatagaaaa gttatatact atctattgaa aatattataa atcagataca
    26461 aagacaggtg aaaccttctg tgttatacta gagatatgtt agatttgaaa gaatacggta
    26521 tcgtcatgtg gccggaggag aaagtcattt ctttccgtga gaaacttctc gcttggtatg
    26581 atgaaaacaa aagagatttg ccttggagga gaagtaaaaa tccttatcac atctgggtat
    26641 ctgaaatcat gcttcagcag accagggtgg atacagttat cccttactac gaaagatttt
    26701 tggactggtt tccaactgtc gaaagtctgg caactgcgcc tgaggagagt ttactgaaag
    26761 cttgggaggg cttgggttat tattctcgag ttcgcaatat gcaggctgca gcccagcaga
    26821 ttatgactga ctttggtggc caatttccaa atacctatga aggaatttcc agcttgaaag
    26881 ggattggacc ttacacagca ggagccattt ccagtattgc ttttaacttg cctgagccag
    26941 ctgtagatgg taatgtcatg cgggtcttgg cgcgtctgtt tgaagtcaac cacgatattg
    27001 ggattccaag taatcgaaaa atttttcagg caatgatgga gatcttgatt aatccagatc
    27061 gtccgggtga ttttaatcaa gccttgatgg acttagggtc tgatattgag tctcctgtaa
    27121 atcccagacc tgaagaaagc ccagtcaagg actttagtgc ggcatatcag aatggaacca
    27181 tggaccgtta tccaattaaa tctcctaaga aaaagccggt tcctatttat cttaaagcct
    27241 tagttgtgaa aaattctcaa ggacaatttt tacttgaaaa aaatgaaagc gaaaagctct
    27301 tggcaggttt ttggcatttc ccctttatag aagttgataa cttttcgcaa gaagagcagt
    27361 ttgacctctt tcatcaggtt gcggaagaaa gtgtgaactt tggccccagt ccagaagaga
    27421 gtttccagca ggactatgac ctagatgttg attggcttga tgtttgtttt gatacagtcc
    27481 agcatgtttt tagtcatcga aaatggcatg tacagattgt agcaggtcag gtgagtgact
    27541 tccatgattt ttcagatagg gaagttcgtt ggctttcacc agaagaattc aagaattacc
    27601 cacttgccaa accccaacaa aaaatctggc aggcttatgc acaagccaac ttagacagta
    27661 gccaagacta gctattgtgt cttctgacta ttttttggta taatagtaga gaaaaaggtg
    27721 aacatatgaa aaaaatacta attgtagatg atgagaaacc aatctcggat attatcaagt
    27781 ttaatatgac caaggaaggt tacgaagttg taactgcttt taatggtcgt gaagcgctag
    27841 agcaatttga agcagagcaa ccagatatta ttattctgga tttgatgctt ccagaaattg
    27901 atggtttaga agttgctaag accattcgta agacaagcag tgtgcccatt cttatgcttt
    27961 cagccaaaga tagtgaattt gataaggtta tcggtttgga acttggggca gatgactatg
    28021 taacaaaacc cttctccaat cgtgagttgc aggcgcgtgt taaagctctt ctgcgtcgtt
    28081 ctcaacctat gccagtagat ggtcaggaag cagatagtaa acctcaacct atccaaattg
    28141 gggatttaga aattgttcca gacgcctacg tggctaaaaa atatggcgaa gaactagact
    28201 taacccatcg tgaatttgag cttttgtatc atttagcatc gcatacaggt caagtcatca
    28261 cgcgcgaaca cttgcttgag actgtctggg gttatgacta ttttggtgat gtccgtacag
    28321 ttgatgtgac tgtacgacgt ctgcgtgaga agattgaaga tacgcccagc cgaccagagt
    28381 atatcttgac gcgccgtggt gtagggtatt acatgagaaa taatgcttga tttactgaaa
    28441 caaaccattt ttaccagaga ttttatcttt atcctgattt tgttaggttt catccttgtt
    28501 gtgaccctct tattactgga aaatagacgt gataatattc agttgaagca aatcaatcaa
    28561 aaggttaaag atttgattgc aggagattat tccaaggttc ttgatatgca aggtgggtct
    28621 gaaatcacca atattaccaa taatttgaat gacttgtcgg aggttattcg tctcactcag
    28681 gaaaatctag aacaagagag taagaggcta aatagtattc tgttttatat gacagatggg
    28741 gttcttgcga ccaaccgtcg gggtcagatt atcatgatta acgatacagc caagaagcaa
    28801 ctggggttgg ttaaggaaga tgttctgaat agaagcattt tggaattgct caagatagaa
    28861 gaaaactatg aattgcgtga tttgattacc caaagtccag aattgttgct agattcccaa
    28921 gatatcaatg gcgaatattt gaaccttcga gttcgctttg ccttgatacg tcgagagtct
    28981 ggctttattt caggtttggt ggctgttttg catgatacga cggagcagga gaaggaagaa
    29041 cgcgaacgaa gactctttgt ttccaatgtt agccatgagt tacggactcc tctgactagc
    29101 gtaaaatcct atcttgaagc cttggatgag ggggctttgt gtgaaactgt agcaccagac
    29161 tttatcaagg tttctcttga tgagaccaac cgtatgatgc gcatggtgac ggatctcctc
    29221 catctttcac gtattgataa tgctaccagt cacctagatg tggaactgat taacttcact
    29281 gcttttatta cctttatcct caatcgtttt gacaagatga aaggacagga aaaggagaaa
    29341 aaatatgagt tggtgagaga ttatcccatc aattctatct ggatggaaat tgatacagat
    29401 aagatgacgc aggttgtcga caatatttta aataatgcta ttaagtattc gccagatggg
    29461 ggtaaaatca ctgtcagaat gaagacaact gaagaccaga tgattttatc catttctgac
    29521 cacggtttgg ggattcctaa gcaggattta ccacgtatct ttgaccgttt ctatcgtgtg
    29581 gatcgtgcta gaagtcgtgc acaaggtggt acaggtctag gactgtctat cgctaaagaa
    29641 attatcaaac aacataaggg ctttatttgg gccaagagtg aatacggcaa gggttcaacc
    29701 tttaccattg tgctccctta tgataaggat gcagtgaaag aagaagtatg ggaggatgaa
    29761 gtagaagact agaatgagtg aaataggctt taaatacagt attttagcgt cgggttccag
    29821 tggaaattct ttttatctgg aaacctcaaa aaagaagctt ttagtagatg caggcttgtc
    29881 tggcaagaaa attaccagtc tgctagctga aattaaccgt aagccagaag acctggatgc
    29941 catcttgatt acccatgagc attcagatca tatccatgga gtaggcgttt tggctcgcaa
    30001 gtatggtatg gatctttatg ccaatgaaaa gacctggcaa gctatggaaa atagtaaata
    30061 tcttggcaag gtggattctt cgcaaaagca tatttttgaa atgggtaaaa ccaaaacctt
    30121 tggagatatc gacatcgaga gttttggtgt aagccatgat gcagtcgcac cgcagttcta
    30181 tcgctttatg aaggatgata agagttttgt ccttttgaca gatacaggtt atgtcagtga
    30241 ccgtatggcg ggcattgtcg aaaatgcgga tggctatctt atcgaggcca accatgatgt
    30301 agagattttg cgatcaggtt cttacgcttg gcgactcaaa caacgaatcc tatctgacct
    30361 tggtcacctt tctaacgagg acggtgctga agctatgatt cggacgctag gaaatcgtac
    30421 taagaagatt taccttgggc atttatctaa ggaaaacaat atcaaggaac tggctcatat
    30481 gaccatggtc aatcagctgg ctcaagctga tctgggagtc ggagtagact ttaaggttta
    30541 tgatacctca ccagataccg caacaccatt gacagagata tagaaagaac gctgagaagg
    30601 tgttcttttt atattgactg aacacctaaa aagtaataca atggtgttac cattaaaaaa
    30661 gggagcacaa aagatgacta ctattacatt aaaagtttct gaagctgata aaacatttat
    30721 gaaagcaatg gctaagtttg aaggagtttc cctttcggaa cttattcgca ccaaaactct
    30781 tgaagcccta gaagatgaat acgatgctcg tgtggcagat ttagcctatc aagagtattt
    30841 agaagacttg gaaaaaggag ttgaacccat tacttgggaa gaaatgatgc atgatttagg
    30901 cttgaaggat gaataatttg tataaattag ttccaacaag acgtttcatc aagcaattga
    30961 aaaaattgga ccgttatacg cagaagctaa ttacaaacta tttacaaatc aatgttttgg
    31021 aagacccaag acgacacgga aaggctttgg ttggtaatcg cgttggtcaa tggcgctata
    31081 gaattggtaa ttatcgagtt atcgtacaaa ttgtagatga tgaattagtt gttgctactc
    31141 tagaagttgg tcatcggaga gatatttatt gaattaaagc tgagtaataa caatatagaa
    31201 agtaaggaga gtaaaaattt gaagaaaaaa tggttttttg cagattatta tgatacaaca
    31261 attattttac ttgctttaat ctctgttatt ctggtattac ttggatttgc tgagatgatt
    31321 gatttggaca atccgcctta tagtattatt gatttagtaa tctggggtgt ttttgtaatt
    31381 gattatagtt ggcgcttttt tattactaaa agaaaatggc gctttattct tgaaaatgtt
    31441 tttgatttat tggctattct ccctttaaat gctattttca cagtttttcg attagggcgt
    31501 atctttcgtt tagttaaact aacaaaatta ctgaaactga ctcgtttact tagaataatt
    31561 ggacttacag gtaaattaga aagaaaaatt agtagattct tacggacaaa tggcctgatt
    31621 tatatcttat atgttaatat ctttattatt ctagtaggaa gttcaatttt atctgtagtt
    31681 gaagaaaaat ccttctcaga tagtctttgg tgggctcttg tgacagtaac tactgttggt
    31741 tatggtgata ttgttccagt ttcccttttg gggaaatggc tagcagtttt actgatgctt
    31801 gtcggtattg gaacaatagg gatgttaaca agtgctttga cgaacttttt tgtaaaggat
    31861 aatccagatg aacagataaa acttgataaa ctccaagatg aattatctag tccgagaata
    31921 ttactagaga aacaatctaa aaagatagaa gaactacata aaatgataca agatttgatt
    31981 gaaaaaacat aataaaaata aagatgagaa aaagtttgaa ctgaggagaa atcaagtaag
    32041 ttttgacaca atagaacgca tattatcagg tataaaaact tgatattatg cgttttattg
    32101 tgggaagatg tataatggat tgaaataaga tatgaacaaa tcgattagga atttaaagca
    32161 ttttataaca acgttttaga gtaacggggt actatttcat ataatacagg aaaaaacaac
    32221 tccctgatga ttcaaggagt tgtctatagt taaattagtt tttagaagct tcttggaatt
    32281 ctggattttt ccatgcttcg tcaataatag cttgcaattc tttagcagat gcttgcattt
    32341 tttgagtttc tgcatcgttc aatggaatgt ttactggacg aacgatacca tgtgcaccaa
    32401 caacagctgg ttgaccgata aagacattct caactccgta ttgaccttct tggaatactg
    32461 aaagtggaag tactgcgttt tcatcgtcaa ggattgcttt agtgatacga gcaagggcta
    32521 ctgcgatacc gtagtatgtt gcaccttttt tgttgatgat tgtgtaggct gcatcacgaa
    32581 caccttcgaa caattcaatc aattcagctt cttgaacatt ttgagtgtct ttaaggaatt
    32641 cttcaaggtt tacaccagcg atgttagcgt gtgaccaaac agcgaactca gagtcaccgt
    32701 gttcacccat gatgtaggcg tgcactgaac gagcatccac atccaatttt tcagcaagtg
    32761 cttgacggaa acgagctgag tcaagtgaag tacctgaacc gataacgcgt tctttaggga
    32821 aaccagagaa tttccaagtt gagtaagtca aaacgtcaac tgggttagca gcaacaagga
    32881 agataccttt gaaaccagat tcaacaactt gagttacgat tgatttgttg atagcaaggt
    32941 ttttacctac aaggtcaaga cgagtttcac ctggtttttg aggtgcacct gcagtgatca
    33001 caacaaggtc agcgtctgca cagtcagagt attgagctgc atagattttt ttaggtgaag
    33061 tgaaggcaag ggcgtgacta aggtcaagcg catcaccaac agctttttca tgcaattgtg
    33121 gaatttcgat aattccaagc tcttgtgcaa ttccttggtt aacaagtgca aaagcgtaag
    33181 atgaacctac agcaccatca ccgacaagga taactttttt gtgttgttta gttgaagtca
    33241 ttgttttaaa catctcctta attttattag gggattttcc ctagacaact tcattctatc
    33301 acttttaaaa aactttgtca cgaatatgcc ttatagttct cgatgtaaac gttttagtgg
    33361 tttagaggct gaaatagatg ggaatttatg gtataatgtt gttacttact aattgtgaaa
    33421 tgaggcattt attaatgcag gataaaaatt tagtgaatgt caatctgaca aaggagatga
    33481 aggcaagttt tatcgactac gccatgagtg ttatcgtagc gcgagctctt cctgatgttc
    33541 gagatggctt aaaacctgtt caccgtcgca ttctctacgg aatgaatgaa ttgggtgtga
    33601 ccccagacaa accccataaa aaatctgctc gtattacagg ggatgtcatg ggtaaatatc
    33661 acccacacgg ggattcctct atttatgaag ccatggtccg tatggctcaa tggtggagct
    33721 accgttacat gcttgtagat ggtcatggga attttggttc catggatgga gatagtgctg
    33781 ccgctcaacg ttataccgag gcacgtatga gcaagattgc tctggaaatg cttcgtgata
    33841 tcaacaaaaa tacagttgat ttcgttgata actatgatgc caatgaacgg gaacccttgg
    33901 tcttgccagc gcgttttcca aaccttttgg ttaatggagc aactggtatc gcggttggga
    33961 tggcaaccaa tattccacct cataatctgg gtgaaaccat tgatgcagtg aagttggtca
    34021 tggataatcc tgaagtgact accaaggact tgatggaagt cttgcctgga ccagattttc
    34081 caactggtgc tcttgtcatg gggaaatcag gtatccataa ggcttatgaa acaggtaaag
    34141 gttcgattgt cctacgttct cgtacagaga ttgaaacgac taagactggt cgtgagcgta
    34201 tcgttgtaac agaatttcct tacatggtca ataaaaccaa ggtgcatgag catattgttc
    34261 gcttggttca ggaaaaacgc attgagggta tcacagcagt acgtgatgag tcaaaccgtg
    34321 aaggtgttcg atttgttatt gaagtcaagc gcgacgcctc agccaatgtt attctcaata
    34381 acctcttcaa aatgacccaa atgcaaacca attttggttt caatatgctc gctatccaaa
    34441 atggtatacc gaaaattttg tctcttcgtc agattttgga tgcttatatc gagcaccaaa
    34501 aagaagtggt tgttcgtcgt acacgttttg ataaggaaaa agcggaagcg cgcgctcata
    34561 tcttagaagg tctcttgatt gcgctagacc atatcgacga agtgattcgt atcatccgtg
    34621 ctagtgaaac ggatgcggaa gctcaagctg agttgatgag caagtttaag ctttctgaac
    34681 gtcaaagtca agctatcctt gatatgcgtc ttcgtcgttt gacaggtttg gaacgcgata
    34741 agattcaatc tgagtatgat gacctcttgg ctctgattgc ggatttagca gatattcttg
    34801 ctaagcctga acgtgtttct caaattatca aagacgaatt ggatgaagtt aaacgtaaat
    34861 tttctgataa acgccgtaca gagttgatgg ttggacaggt cttgagtctc gaggatgagg
    34921 acttgattga agaatcggat gtcttgatta ccctttctaa cagaggctac attaagcgtt
    34981 tggatcagga cgagttcact gctcaaaaac gtgggggtcg tggtgtccaa ggaacgggag
    35041 tgaaagatga tgactttgtt cgtgagttag tgtcaactag tacccatgat catctgctct
    35101 tcttcacaaa caagggacgt gtctatcgtc ttaaaggtta tgaaattcct gagtatggtc
    35161 ggactgccaa agggctacca gtagtcaatc tcttgaaatt ggatgaagac gaaagtattc
    35221 agacggttat caatgttgag tctgatcgca gtgatgatgc ttatctcttc tttacaaccc
    35281 gtcacggtat tgtgaagaga accagtgtta aggagtttgc caatattcgt caaaatggtc
    35341 tcaaagcgct gaatttaaag gatgaagatg agttaatcaa tgtcttgttg gcagaaggag
    35401 atatggatat tatcattggt accaagtttg gttatgcagt tcgctttaat caatcagccg
    35461 ttcgtggtat gagccgtatc gccactggtg tgaaaggtgt taaccttcgt gaaggagaca
    35521 cagttgttgg tgccagcttg attactgatc aagatgaggt tcttattatc acagaaaaag
    35581 gatatggtaa gcgtacagtc gctactgaat acccaacaaa aggtcgtggt ggtaagggaa
    35641 tgcagacagc taaaattacc gaaaaaaatg gcttgctggc cggtcttatg actgttcaag
    35701 gggatgagga tttgatgatt atcactgata caggtgtcat gattcgaacc aatcttgcca
    35761 atatttcaca aacaggacgt gcaactatgg gagttaaagt aatgcgcctg gatcaagatg
    35821 ctcagatagt gactttcaca acggttgcgg tggcagaaaa agaagaagtt gggacagaaa
    35881 acgaaacaga aggtgaagca taatgtctca aaaaaataat aaaaagaaaa acaagcgaaa
    35941 aaatctgctg acaaatatcc tagcaggatt tctgatatta ctgtcactgg ctttgatttt
    36001 taatactcaa attcgaaata ttttcatagt ctggaatacc aataagtatc aagttagcca
    36061 ggtatcaaaa gaaaaattag aagaaaatca ggatacagaa ggcaattttg actttgattc
    36121 tgtcaaagct atctcttcgg aagctgttct aacttctcaa tgggatgctc aaaaattacc
    36181 agttattggg ggaattgcaa ttcctgaatt ggaaatgaat ttgccgattt ttaaaggact
    36241 tgataatgtt aatctcttct acggagctgg tacaatgaaa cgcgagcaag taatgggaga
    36301 aggaaattat agtctagcta gtcaccatat ctttggtgtt gataatgcta ataaaatgtt
    36361 attttctcct ttagataatg ctaaaaatgg catgaagatt tatctaaccg ataaaaataa
    36421 agtttatact tatgaaatac gtgaagtcaa acgtgtgaca ccggatcgtg ttgatgaagt
    36481 tgatgataga gatggggtca atgaaatcac attagtaacc tgtgaagacc ttgctgctac
    36541 agaacgtatt attgtcaaag gtgatttgaa agaaacaaaa gattattcac aaacatctga
    36601 tgaaatccta acagctttca atcaaccata taaacaat
//
LOCUS       DAVLDI010000016        36604 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLDI010000016 DAVLDI010000000
VERSION     DAVLDI010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36604
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.016"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            20..5620
                     /locus_tag="VXD01_000803"
     CDS             20..5620
                     /locus_tag="VXD01_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEV0601233.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKLAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDLDK
                     GYSGFRAAPAPTNKLVTNLGNNTVFTDISRGSHTFRGNGNSRGGNPIHFDVTTTRVGN
                     RVEFSIAYSGPGEFVNNNFLLDKGNGFGEPSRATISTNRLRDQTKDIRKGANFVSHSS
                     YSLTSAVETNSNQTIRFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQIIY
                     KVHQLGNETILGLPISNSVIKEVKPRIMQIGVAKDLIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGVQGERGLTGAQGQAGRDGVTPTVTVKD
                     NKNDGTHTITINDGRGNVASTVVRDGFDGASPLVATQRNEADKTTTVIFYYDQNGNNE
                     LDASDKKLKEVIIADGAKGEQGLQGRDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPG
                     KDGKSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSV
                     QNGKNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPD
                     VTTTIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEG
                     NIKGPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEA
                     HQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDG
                     HSTDITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENN
                     DGKYTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPE
                     KPLAVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGAT
                     GQDGQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSP
                     SRIRRDTDAAATPTRNGIRVTVYDDVNDNGVYDGGVDKVLNSKDIYNGIDGRDGSAPT
                     ITTKDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGS
                     TKETVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTE
                     NPDGSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTT
                     ETTVRDGKSPKVTITDEQNGTHKISVLNGDGTTTETIITDGKSPVATVRDNQDGTYTI
                     RVENGNGTVSETTVRDGKSPTAKVVDNGDGTHTITVVNSDGTTTTTTVRDGREPKLEV
                     IDNNDGSHTIKVTGADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSII
                     KDGKDGKDSVSPTVTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGD
                     GSHTITIINSDGTVTKTVIKDGKDGRDGRDGRDGKDGKDGKCGCQDKPVTPSNDKPVP
                     PTPNVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVAPTTGKENRGDKLPETGSQ
                     SDYISVLLGSGILLSLYVGRRKED"
     gene            complement(5857..6405)
                     /locus_tag="VXD01_000804"
     CDS             complement(5857..6405)
                     /locus_tag="VXD01_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV0601234.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALASKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            6726..7214
                     /locus_tag="VXD01_000805"
     CDS             6726..7214
                     /locus_tag="VXD01_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV0601235.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            7211..8398
                     /locus_tag="VXD01_000806"
     CDS             7211..8398
                     /locus_tag="VXD01_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0601236.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEVA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEESEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            8391..8615
                     /locus_tag="VXD01_000807"
     CDS             8391..8615
                     /locus_tag="VXD01_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0601237.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEV"
     gene            8772..10118
                     /gene="asnS"
                     /locus_tag="VXD01_000808"
     CDS             8772..10118
                     /gene="asnS"
                     /locus_tag="VXD01_000808"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV0601238.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            10271..10561
                     /locus_tag="VXD01_000809"
     CDS             10271..10561
                     /locus_tag="VXD01_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV0601239.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            10573..11043
                     /gene="ssbA"
                     /locus_tag="VXD01_000810"
     CDS             10573..11043
                     /gene="ssbA"
                     /locus_tag="VXD01_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV0601240.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            11075..11314
                     /locus_tag="VXD01_000811"
     CDS             11075..11314
                     /locus_tag="VXD01_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV0601241.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            11609..13009
                     /locus_tag="VXD01_000812"
     CDS             11609..13009
                     /locus_tag="VXD01_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV0601242.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIGKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            13011..13370
                     /locus_tag="VXD01_000813"
     CDS             13011..13370
                     /locus_tag="VXD01_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV0601243.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHYLKKKK"
     gene            13424..14173
                     /locus_tag="VXD01_000814"
     CDS             13424..14173
                     /locus_tag="VXD01_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV0601244.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPHSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            14163..14462
                     /locus_tag="VXD01_000815"
     CDS             14163..14462
                     /locus_tag="VXD01_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV0601245.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            14533..15468
                     /locus_tag="VXD01_000816"
     CDS             14533..15468
                     /locus_tag="VXD01_000816"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV0601246.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            15555..16067
                     /locus_tag="VXD01_000817"
     CDS             15555..16067
                     /locus_tag="VXD01_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV0601247.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAAFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERDLHDSDF"
     gene            16092..16700
                     /locus_tag="VXD01_000818"
     CDS             16092..16700
                     /locus_tag="VXD01_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV0601248.1"
                     /translation="MFGELIRYLDQYEDVILREIKSQFPDVAVDKLMEEYIKASLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDRKYELAIDFDKERLTFYLA"
     gene            16801..16995
                     /locus_tag="VXD01_000819"
     CDS             16801..16995
                     /locus_tag="VXD01_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0601249.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(17041..18486)
                     /locus_tag="VXD01_000820"
     CDS             complement(17041..18486)
                     /locus_tag="VXD01_000820"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV0601250.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKILAFTGTKGKTTAAYFAYNILSQRYPTALLSTMNTTLDGTTFFKSSFS
                     TPENIDLFDMMAQAVKNGRSHLVMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            18592..20214
                     /locus_tag="VXD01_000821"
     CDS             18592..20214
                     /locus_tag="VXD01_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0601251.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            20415..22376
                     /locus_tag="VXD01_000822"
     CDS             20415..22376
                     /locus_tag="VXD01_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0601252.1"
                     /translation="MKKSKSKYLTLAGFVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRATTNDIVTNLVDGLMENDQYGNYVPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGI
                     KALDDQTVQYTLARPEPYWNSKTTSTILFPVNADFLKSKGDDFGKVDPANILYSGPFL
                     MKAFVSKSVIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQDALVRNFTDGAYSYARLYP
                     NSSSFEGIKEKYKDDIIYSMQDATSYYWNFNLDRQAYKFTSKTTDIEKKSTQEAVLNK
                     NFRQAINFAYDRTSYGAQTQGEDGATKILRNLVVPPTFVSIKGKDFGEVVASKMVNNY
                     GKEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDATVDQASKKGIQE
                     VSSMKQSIEAALGTENVVIDIQQLSTEDYDNSSYLAQTAIQKDYDLYNGGWSPDYLDP
                     STYLDIFSVKNGGVLQNLGLDPGEANDKAKAVGLDTYTQMLEEANKEQDPAKRYEKYA
                     DIQAWLIDSSLAIPNVSLGGTPSLRKTVPFSAPYSLAGNKGVESYKYLKVQDKIVTTD
                     EYAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            22548..22781
                     /locus_tag="VXD01_000823"
     CDS             22548..22781
                     /locus_tag="VXD01_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEV0601253.1"
                     /translation="MKLKLLRVDTKVIMWSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            22787..24229
                     /locus_tag="VXD01_000824"
     CDS             22787..24229
                     /locus_tag="VXD01_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601254.1"
                     /translation="MRKKVIEGLIYAEKSFFDKSQSGELTSAIVNDMSVIREFLITTF
                     PNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMMFIILPLSNISEKYSRRLQEEIG
                     FLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSFETPFALLFI
                     FATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTIYSSSKGSSVA
                     LENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPS
                     GSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDN
                     LCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIART
                     YLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLE
                     EGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            24387..25481
                     /locus_tag="VXD01_000825"
     CDS             24387..25481
                     /locus_tag="VXD01_000825"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0601255.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            25489..26655
                     /locus_tag="VXD01_000826"
     CDS             25489..26655
                     /locus_tag="VXD01_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV0601256.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVMDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            26748..29846
                     /locus_tag="VXD01_000827"
     CDS             26748..29846
                     /locus_tag="VXD01_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0601257.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            29894..30511
                     /locus_tag="VXD01_000828"
     CDS             29894..30511
                     /locus_tag="VXD01_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV0601258.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            30522..31856
                     /locus_tag="VXD01_000829"
     CDS             30522..31856
                     /locus_tag="VXD01_000829"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV0601259.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            31866..32330
                     /locus_tag="VXD01_000830"
     CDS             31866..32330
                     /locus_tag="VXD01_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0601260.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            32327..32821
                     /locus_tag="VXD01_000831"
     CDS             32327..32821
                     /locus_tag="VXD01_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0601261.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            32902..34557
                     /gene="mltG"
                     /locus_tag="VXD01_000832"
     CDS             32902..34557
                     /gene="mltG"
                     /locus_tag="VXD01_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV0601262.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADESQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATEIVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            34628..35110
                     /gene="greA"
                     /locus_tag="VXD01_000833"
     CDS             34628..35110
                     /gene="greA"
                     /locus_tag="VXD01_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV0601263.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(35278..35355)
                     /locus_tag="VXD01_000834"
                     /pseudo
     CDS             complement(35278..35355)
                     /locus_tag="VXD01_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            35483..35881
                     /locus_tag="VXD01_000835"
     CDS             35483..35881
                     /locus_tag="VXD01_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0601264.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            36339..>36604
                     /locus_tag="VXD01_000836"
     CDS             36339..>36604
                     /locus_tag="VXD01_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0601265.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSVT"
BASE COUNT        11421 a         6765 c         8164 g        10254 t
ORIGIN      
        1 tactatctag gagtttaaaa tgaaacattc acataaaaaa tcatttgact ggtatagcat
       61 gcaacaacgt tattctattc gtaagtatta ctttggtgca gttagtgtct tgctcggtac
      121 cgctttggta ttaggtgcag cagctagtgt ccaaacagta caagcggaag aaaacaaaca
      181 agaaactacc aatagtattt ctgttggtag gggagaagca gctactaaac tagcagaggt
      241 ttctgcgtct aataaagaga aaacctatgc agctccaact gtagctaatc cagtagaaac
      301 gactccagtt aaaactggag aagttactaa accagcagaa aaagttgaag aagcaaaaga
      361 caaaaaagag gaagtaacgc atcaagatgc tattgacaag tcaaaattgt taacggctct
      421 ttcgcgtgct aaaaagttag aaagcaagtt atatacagaa gcaagtgctg ctaacttgca
      481 aacaagtatc caagctggtc aaagcttgct tgggaaagca gatgcatctg aagctgaatt
      541 atcagcagca gagtcatcta ttcaatcatc tattattggt ctagaacttc gttctaactc
      601 taacaaagga actgtatcag aaactcctgt agcgaagaaa gctaatatag ttgaagcgaa
      661 ggaagagact aatccagctg caacaactga tcgttcagct gttgatagtg ctgttttgcc
      721 aactagcaca gctgccaaag tagaaacaac ttcagctcca gcatctatta atgaaatctt
      781 gaaaccaggt ttgagccttt ctgatgctcg ccaaaatcca gctatccgta aagaagactt
      841 ggataagggg tatagtggtt ttagagcagc acctgctcca acgaacaaac tagtaactaa
      901 tctaggaaat aatactgttt tcactgatat tagcagaggg tctcatactt tccgtggtaa
      961 tgggaattca cgtggtggaa acccgattca ttttgatgta acaacaacta gagttggaaa
     1021 tagagtagaa ttctcaattg catattctgg tccaggtgag ttcgttaata ataactttct
     1081 cttagacaaa gggaatggat ttggagaacc atctcgtgca actatttcaa caaacagatt
     1141 aagagatcaa actaaagata taagaaaggg tgcaaatttt gtatctcatt caagctacag
     1201 tttaacatct gctgttgaaa caaacagtaa tcaaactatt agatttagtt tacctatagc
     1261 caaccctaat ggtgatctgt ctgttcgatt aagacctgtt acttttaatg taggtcaagg
     1321 ggaatcagga tctgcaacta gtaatgatcc atatagtaac tctaactatt acttcagaga
     1381 aaaaccactc ctcttggatg caaatccaaa tggtggtact aataataaga ctgtttcaga
     1441 agacattgac ttccaaactg tctatcttcc aactagtaag ttaccagaag gtcaaactag
     1501 attagttcga gaaggtgaaa aaggacaacg tcaaatcatc tataaagttc atcaattggg
     1561 taacgaaaca atcctaggat tgccaattag taattcagtt attaaagaag ttaagccacg
     1621 tattatgcaa attggtgtgg ctaaagatct aatcgataca gtaaaaccac gtgttgatca
     1681 aaataaagtc ggtgatacaa ataacctcac tttctatctt gataacgatg gaaacggtgt
     1741 ttatactgag ggcgtagacg aacttgttca aaaaattgct attaaagatg gtgctaaagg
     1801 tgaaaaagga gtccaaggcg aacgcggcct gactggagcg caaggtcagg caggtcgtga
     1861 cggtgtaact ccaaccgtaa ccgttaaaga taataaaaat gacggcactc atactatcac
     1921 tattaacgac ggtagaggta atgttgcaag tactgttgta agagatggtt tcgatggcgc
     1981 aagtccatta gttgcgactc aacgaaatga agcagataag acaacaactg ttatcttcta
     2041 ttatgatcaa aatggaaata atgaattaga tgcttctgat aagaaattaa aagaagttat
     2101 tattgcagat ggtgccaaag gtgaacaagg tcttcaaggt cgtgatggag ctcaaggacc
     2161 aaaaggcgca gatggacaaa gaggaccagc gggaccacaa ggaccaaaag gagaacaagg
     2221 taatccagga actccaggta aagatggaaa atctctaatt gctgttaaaa atggaactga
     2281 aacaaaagtc tatgtagagg atccggctag accaggacaa ccacttaatc caaaccaacc
     2341 attagcaact atcactgatg gaagaaatgg tactaatgga caatcaccaa caattacagc
     2401 gacacgaagt gttcaaaatg gtaaaaatgg tgtattagta acaattacac cagtaggagg
     2461 tcgtccacaa acaacatttg tagaggatgg acaaaaaggt gctgatggga aaaccccaac
     2521 agtaacaata actgaggggc aaaacggcac acatacatta acggttcata atccaggaag
     2581 tccagatgtg acaactacga tccgtgatgg agctacagga caagcaggtc gtgatggtaa
     2641 agatgtatta aacggaaaag taaatccaca accaaaccaa ggtaaaaatg gagataaata
     2701 tattaatacc gaaaccggtg atgtctatgt taaaaacaat ggaaactggg ataaagaagg
     2761 caacatcaaa ggccctaaag gggacaaagg tgcagatggt gctaaaggcg aaaaaggaga
     2821 ccaaggcgaa cgcggcctaa ctggagcgca aggagctaaa ggtgcggatg gcgcagtagg
     2881 tcgtgatgga cgtgacggta aagacgtgtt gaacggcaaa gctaacccag aagcacatca
     2941 aggtaaagac ggcgataaat acgttaatac agaaacaggc gacgtcttcg ttaagaataa
     3001 cggcaactgg gataaagagg gcaacatcaa aggccctaag ggtgacaaag gtgaacgcgg
     3061 agaagatggt aagactccag aagtaactgt aactccaggt aaagatggcc atagtactga
     3121 cattacattc actgttccag gtaaagatcc agttacagta aatgttaagg acggagaaaa
     3181 tggtctgaac ggtaaaactc caaaagttga tttacttcgt gtccaaggaa aaaacggaaa
     3241 tccatctcat acaattgtga cattctatac agatgaaaac aatgacggca aatatacacc
     3301 aggaactgat gaacttctag gttcagaaat gattaaagat ggtgctaaag gcgcggacgg
     3361 acgagatggt aaatcattgc ttactgtcaa ggatggtaaa gaaactaaag tttaccaaga
     3421 agatccagct aacccaggac aaccattaaa tccagaaaaa ccacttgcgg taattagaga
     3481 tggagtagat ggaaaatcac ctacagttac agctgttcgt aaagatgaag cagggcataa
     3541 aggtgtagaa atcactgttg ataaccatga tggttcacaa ccaactacag tctttgttca
     3601 agatggtgct aagggagaaa ctggtgcaac cggtcaggat ggacaaactc ctacaatcac
     3661 tactcaacgt ggacaagatg gccaaagcac tgttgtaact atcacaacat caggtaaaga
     3721 tccagtaacc ttcactgtaa aagatggtaa gaatggtaaa gatggccgtg caccgaaaat
     3781 caaagtagaa gatattactt caccttcaag aattagacgc gatacagatg ctgctgcaac
     3841 tccaacgcgt aacggtatcc gtgttacagt ttatgatgat gttaatgaca atggggtata
     3901 cgacggaggt gtcgataaag tattaaatag taaagatatt tataacggta tagatggacg
     3961 tgatggttca gctccaacta ttactacaaa agataatgga gatggaacac acactatcac
     4021 agttcaaaat cctgatggtt ctgaatcaac aactgttgtt aaagatggta aagacggtaa
     4081 aactgcgaat atcactacaa cagaaaaccc agatggaagc cacacaatta cggtgacaaa
     4141 tccagatggt tcaactaaag aaactgttgt taaaaacggt aaagacggta agactcctaa
     4201 agttgaagta acggataaca acgatggaac acacacagtt aaagtgacgg atggagacgg
     4261 caatgttacc aacgctatca tcaaagatgg taaagatggt aaagctgcaa cagcaacaac
     4321 tactgaaaat ccagatggaa gccacacagt aacaatcact aacccagacg gaactaagaa
     4381 tgagtttgtt gttaagaatg gacgtgacgg tgttgacgga cgtactccaa ccgcatctgt
     4441 tcgtgataat ggagacggaa gtcatacaat cgttattaca aatccagaag gtgtgacaac
     4501 tgaaaccaca gttcgtgatg gtaaatcacc aaaagtgact ataactgatg aacaaaatgg
     4561 aactcataag atctctgttc taaatggtga cggaacaact actgaaacaa tcattacaga
     4621 tggtaaatca ccagtagcaa cagttagaga taaccaagat ggtacttaca ctattcgtgt
     4681 ggaaaacggt aatggtactg tttctgaaac cacagttcgt gacggtaaat caccaactgc
     4741 taaggttgtg gataatggag atggaactca cactatcaca gttgtgaact cagacggaac
     4801 aactacaaca actacagttc gtgatggtag agaaccaaaa cttgaagtta ttgataacaa
     4861 cgatggttca cacactatta aagtgacagg tgctgatggt aaaggaacga caactacaat
     4921 ctttgatggt aaatcaccaa aagcgaacat cgttgataac ggagatggaa ctcatacatt
     4981 aacaatcgta gattctgatg gtcgtgaata caaatctatt atcaaagatg gtaaagacgg
     5041 caaagatagc gtttcaccaa ctgtaactgt taaaaataat aacgatggaa ctcacgttgt
     5101 tacaatcact aatccagatg gaagtaagac agaaatggtg attaaagacg gtaaagatgg
     5161 taaatcacca aaagtttctg ttgaagataa tggtgatggt agtcatacaa tcacaatcat
     5221 caattctgat ggaactgtga caaaaacagt tattaaagat ggcaaagatg gtagagatgg
     5281 acgtgatggt cgagacggca aagacggtaa agatggaaaa tgtggatgcc aagacaaacc
     5341 agtaacacca tcaaatgaca aaccagttcc tccaacacca aatgtgccga caccagaagt
     5401 accggttaaa ccagtaccag cggttccaga acaaccagta gtaccaacac cggctcaacc
     5461 agcaactcca gtaaatgcta acccagtagc accaactaca ggtaaagaaa accgtgggga
     5521 caaattacct gaaactggaa gccaatctga ttatatctct gttcttttag gtagcggtat
     5581 tctattgagc ctatatgtag gacgaagaaa agaagattaa tcagccaaaa gcagtcacta
     5641 atttctcgaa agaagatgat aagtgataga tctcgaatga aagaatattc ttagaatgat
     5701 tttcctatga tggaaaagac tgctaaaaac cttgagtggt aacgctcaag gtttttttgg
     5761 atggctgatg tttgtctgaa aatcttgatt gagaaataaa aagccaccct attaggtggc
     5821 tataattgat ttagactttc taaaattttc tattttttac tgaatcgctt cgaccaagtc
     5881 ttgagcttgt ttttcaagtg agtttaggac tgtttcttca agaaccaatt ttccgtctgc
     5941 ccaggcagag tcattaacac gtgcagcagt gaaatcacca acgccttgtg tacggataaa
     6001 tggcaagagg tctttgtaga tagcgaaaag ttgatcgtgc cctgcattgg ctacagatga
     6061 tactgtgaca aacttgtctt gaagggcaga aacgccacgt gtatcagaca agtcaagggc
     6121 acgagatagc cagtcaagca agtttttcac tgtaccaggg atagagaagt tgtagactgg
     6181 agagaaaatc cagatagcat ccgcaacgag aactgcttca cgagcggcag ctacagctgg
     6241 atgtgttggg acttccaaat cttggctgaa gagaggaagg gctgaataat caaggtagct
     6301 aacttccgct ttactagcaa gtgctttctc agcttcgagc gccatttggt ggttgaaaga
     6361 accttgacgt agtgatccga cgataaataa tactttttta gacatgatgt gtctcctttt
     6421 tcttaaaatt tcgagaactc tctcgttgtt ataaaatata ttacaacaaa acaaaagaac
     6481 ttgcaagaaa tttgctcaga gtttatttga aaattgtaaa atttcggaaa ctctaatcat
     6541 ttgtgactga aaaagtaaga actgtttcac tttaaaaatc ggttttgttt gaagggagaa
     6601 atagaattgg ttgctcaaag cacagctttg aggttgcaga taaagctgac gtggtttgaa
     6661 gagattttcg aagagtattc ttatattcac ttgtaataaa gcttaataga tggtaaaata
     6721 gacgagtgaa aaaaagacaa aacaaagcaa aaaataatct actgtggcag tatggtctag
     6781 ggatgacgat tttgtttgtg gttatcagtg cttcctttct gtatatggtt tctcttagca
     6841 tgaaacccta tcaaacagct aaaagtgaag gagaaaaatt agctcagcag tatgcaggat
     6901 tagagcaggt cgatcaggtt gatttataca atggcttgga atcttattac agcgttcttg
     6961 gtcgtaataa acagcaagaa gcgcttgctg tcctgattgg taaagatgat cataagattt
     7021 acgtttatca gctaaatcag ggtgtttcac aagaaaaagc agaaacggtt tctaaggaaa
     7081 agggagctgg cgaaattgac aagattatct ttggtcgtta tcaagataag ccaatctggg
     7141 aagtcaagtc aggatctgat ttttatctag tagattttga aacaggagca ttggtcaaca
     7201 aggagggcct atgaaattat ccaaccgtgt tttagaaatg gaagaaagtg tgactttggc
     7261 tgctggagcc cgtgccaaag cactgaaggc tgagggtaga gatattttgt ctctaacctt
     7321 gggtgagcca gatttcacta ctcccaaaaa tatccaagat gccgccattg catcgattcg
     7381 agatgggcgt gcttcttttt atacagtaac ctcaggtctg ccagagctta aggcggtggt
     7441 caatagctac tttgagcgct tttacggcta ttctgtagcg tcaaatcaag tgacagtcgc
     7501 tgcgggagcc aaatattctc tctatacctt ctttatggct gtggtcaatc caggtgatga
     7561 agtcatcatc ccaaccccat actgggttag ctatggagat caggtcaaga tggcagaagg
     7621 cgttcccgtc tttgtttctg ctaaggaaga caatcacttt aaggtgaccg tagagcagtt
     7681 agaagtagct cgcactgaca agaccaaggt tttggtgctg aattcgccat ctaatcccac
     7741 aggtatgatt tacacccgtg aggaactctt ggcaattgga aactgggctg tagaaaatga
     7801 tattctcatc ctagcagacg atatctatgg ccgcttggtt tataatggtc atgagttcac
     7861 accgatttct agcctatcgg aagcgattcg caagcaaaca gtggtcatca atggtgtgtc
     7921 taaaacctat gccatgactg gttggcggat tggttatgcc gttggagaag cagacattat
     7981 cgctgccatg tccaagattg caggtcaaac aacttcgaat ccgtcagcag tagcccaata
     8041 tgcagcagtt gaggctctat caggtgagca agatactgta gaaagcatgc gtcaggcctt
     8101 tgaggaacgt cttaatacca tctatcccct ccttgcagag gtgccaggat ttgaagtggt
     8161 caaaccgcaa ggggccttct atctcttccc aaatgtcaaa aaggccatgg agatgaaagg
     8221 ctacacggat gtgacagact ttacaactgc tatcttagaa gaatccgaag tggccttggt
     8281 aacaggagct ggatttggag caccagaaaa tgtccgcctc agctatgcga cagacctaga
     8341 cacgcttaaa gaagcagtcg aacgcttgaa agcatttatg ggtagtgaga atgattgatc
     8401 attttgagat taaggtaaag gatttacaaa tttcagaagg attttatagg agttttctcg
     8461 ctcctttgga ctataaattg gcttttaaga ctagttctct aattagtttt ctatccccga
     8521 acagccctca tcctggtggt gatttttggc tgactcaggg aacacaagat cctgttcatt
     8581 ttgctttttt agcagaaaat aaggaagaag tttaggcttg ttatgaggct ggcttagagg
     8641 caggtgggcg agacaatggg gctcctggtt atcgaagtga gcgtccgatt tactatgctg
     8701 cttttatgat tgacctggat gggaacaata tagaggtggt ttgccataaa gaataaaaaa
     8761 gaaaaggaaa aataatgaca aaacgtgtaa cgattattga cgtaaaagac tatgttggtc
     8821 aggaagtgac gattggcgct tgggttgcca ataaatcagg aaaagggaaa atcgctttct
     8881 tacaattgcg tgatggaaca gccttctttc aaggtgtggc ttttaaacca aactttgtcg
     8941 aaaaatttgg tgaagaagtg ggacttgaga agtttgatgt tatcaaacgc ttgagccaag
     9001 aaacgtctgt ttatgtgaca ggtattgtca aagaggacga acgttctaaa tttggctatg
     9061 agttggacat cacagacatc gaagtgatcg gtgaatctca agactaccca atcacaccaa
     9121 aagaacacgg aacagacttt ttgatggata accgtcactt gtggctacgc tctcgtaagc
     9181 aagtagctgt gttgcaaatc cgtaacgcta ttatctatgc aacttatgag ttctttgaca
     9241 agaacggttt tatgaagttt gacagcccaa ttctttcagg aaatgcggca gaagattcta
     9301 cagaactctt tgaaactgac tacttcggaa cgccagccta cttgagccaa tcaggtcaac
     9361 tttacctaga agcaggggct atggctcttg gtcgtgtctt tgactttggt ccagttttcc
     9421 gtgctgaaaa atcaaaaaca cgccgtcact tgactgagtt ctggatgatg gatgctgagt
     9481 actcatactt gacacatgat gagtcgcttg acttgcaaga agcttatgtg aaagctcttc
     9541 tacaaggtgt tcttgaccgc gcgcctcaag ccttggaaac cttggaacgt gatacagaac
     9601 tcttgaaacg ctacattgca gagccattca aacgtatcac ttacgatcaa gccattgacc
     9661 tcttgcaaga gcatgaaaat gatgaagatg ctgactacga gcatcttgag catggtgatg
     9721 actttgggtc accacacgaa acttggattt caaaccactt tggtgtgcca acatttgtca
     9781 tgaactatcc agcagccatc aaggccttct acatgaaacc agttcctgga aatccagagc
     9841 gcgtgctttg tgcagacttg cttgctccag aaggctatgg agaaattatc ggtgggtcta
     9901 tgcgtgagga agattacgat gcccttgtcg ctaagatgga tgaacttggc atggatcgta
     9961 cagaatatga attctacctt gaccttcgta aatacggtac agttccacac ggaggatttg
    10021 gtatcggtat cgaacgtatg gtaaccttcg cagcaggaac aaaacatatc cgtgaagcta
    10081 ttccattccc acgtatgttg caccgtatca aaccataaga acaggaaaac gcccatgtgg
    10141 cgttttttcg aattctagtg tttttacttg cgtaaaaaaa ttttttctag tataatagtt
    10201 tattgtgagc gaacctcact taccccttgc aaagtcttgg ggtcattaga ccaaaaggag
    10261 gaacatatca atggctaaat acgaaattct ttatatcatt cgtccaaaca ttgaagaaga
    10321 agctaaaaac gctttggtag cacgttttga ctctattttg actgacaacg gtgcaactgt
    10381 tgttgaatca aaaacttggg aaaaacgtcg tcttgcatac gaaatccaag atttccgtga
    10441 aggactttac cacatcgtta acgttgaagc aaatgacgat gcagctctta aagagtttga
    10501 ccgtctttca aaaatcaacg ctgacattct tcgtcacatg atcgtcaaaa ttgacgcgta
    10561 agaaggtaaa ctatgattaa caatgttgta cttgtagggc gtatgacacg tgacgctgag
    10621 ttgcgttata ccccatcaaa tgtagcagtt gcgactttta ctcttgcagt aaaccgtaca
    10681 tttaagagtc aaaatggtga acgtgaggct gattttatca atgtcgttat gtggcgccaa
    10741 caggctgaaa atcttgctaa ctgggctaaa aaaggctcac ttatcggggt gacaggtcgt
    10801 atccagactc gtagttacga taaccagcaa ggacaacgtg tctacgtgac agaggtcgtg
    10861 gctgagaatt tccaaatgtt ggaaagccgt agtgtgcgtg agggtcacac aggtggagct
    10921 tactctgcac caactgcaaa ctattcagca cctacaaatt cagtaccaga cttttcacgt
    10981 aatgaaaatc catttggagc aacaaaccca ttggatattt cagatgatga tttaccattc
    11041 taatggacaa ctaaacttat aaaggagaaa aaacatggct caacaacgtc gtggcggatt
    11101 caaacgccgt aaaaaagttg attacatcgc agcaaataaa attgaatatg ttgattacaa
    11161 agatactgag cttcttagcc gtttcgtttc agaacgtggg aaaatccttc ctcgtcgtgt
    11221 aacaggaact tcagctaaaa accaacgtaa agtaacaaca gctatcaaac gcgctcgcgt
    11281 aatggctttg atgcctttcg taaacgaaga ttaaagaaaa gacccggttg ggtctctttt
    11341 tcatgagctt gaaaacaaga aagcgaatta agaccccaac gggtcttttt tcacaagctt
    11401 tgaaatgaga gagcgagtta ggctcagtgg ctcccttttt acgagtttga aaacaagaga
    11461 acacattaca agcacgatgg agctttttca taaatatgtc tcttttctca tccaagaaat
    11521 taaaataaaa atgataaact ttttgaaaat aggggatttg cctactttat gatataatgg
    11581 aaagagttag attgaaagag gtagtgagat ggacgcgaaa ttaagataca aggcaaagaa
    11641 gatcaagatt gtcttttttg atattgatga tacattgcgg aattcaaaga cagggtttat
    11701 tccaactaca attcccactg tttttaaaca gttgcgtgaa aaaggaattt taacaggaat
    11761 cgcctctgga cgtggcattt ttggtgttgt tccagagatt cgtgatctca agcctgactt
    11821 ttttgtaact ttgaatgggg cttatatcga agataaaaaa ggtcaggtca tttatcagca
    11881 tcagattgga aagtcagatg ttgaggagta tatctcttgg gctaagcaag aaggaattga
    11941 gtatggcttg gttgggagtc atgatgccaa gttgtcgact cgcaccgata tgatgagtga
    12001 agctatcaat ccaatttatc ccgacttaga tgtagatccc gatttccatg aaaaagaaga
    12061 tatctatcag atgtggactt ttgaagataa gggagatgac ttgcacttgc ctgacagtct
    12121 ctcagacaaa cttcgcatgg ttcgttggca tcaacattcc tctgatattg tgccgatttc
    12181 aggctccaaa gcgacggggg tggaaaaggt tgtggaacac cttggcttga aaccagagaa
    12241 ggtcatggtt tttggagatg gtctcaacga cttggaactc tttgattatg ctggaatcag
    12301 cgttgccatg ggaatttctc atgataaaat caaagaaaaa gcagattata ttacaaaaac
    12361 attagaagaa gatggcattt ttgatgcctt agaagtattt ggtatggtag aaaaagaatt
    12421 gcattttcca caagtagaca ttgaaacagt agaaggtcct cttgcgacta ttaagaccaa
    12481 tcacggagac ttacgtatca agcttttccc tgaacatgct cctaaaacag tggctaactt
    12541 tgtatctctt tcaaaagatg gctactatga tggtgtcatt ttccaccgta ttatcaagga
    12601 ctttatgatc caaggtggag acccaactgg aactggtatg ggtggcgagt caatctacgg
    12661 cgaatctttt gaggatgaat tctcagaaga gctttacaat atccgtggtg ctctttccat
    12721 ggcaaatgct ggtccaaata ccaacggcag ccagttcttt atcgtgcaaa accaacacct
    12781 accttattct aagaaagaaa ttactcgtgg tggttggcca gaaccgattg cagaaatcta
    12841 tgccaatcaa ggtgggacac ctcacctaga ccgccgtcac acggtttttg gtcagttagc
    12901 tgatgaagca tcttacgctg tcttggatgc cattgctgct gttgagacag gagctatgga
    12961 caagccagtt gaagatgttg taattgaaac tattgaaatc gaggactaag atgaaaatcg
    13021 gtgataagct aaaggggcgt attacaggga ttcagcccta cggtgccttt gttgagttag
    13081 agacgggtga tacggggctg attcacattt cagaaattcg gacaggattt attgaaaata
    13141 ttcatgaaac cttgaaagtc gatgaagagg ttcaagttca ggtagtggat ttagatgaat
    13201 ttacggggaa agccagtctt tctatccgca ctttggagga agaaaagtac cagtttccta
    13261 gacggagacg cttttcaagc gaccgcttta actacggttt tgctcccttt cgacgaatgc
    13321 taccaatctg gactggagaa gccctgcact atttaaaaaa gaagaagtag tttagagttt
    13381 tatatttttt gtaatgttaa tataaatttg ctataatagg accatggaag aagaacaatt
    13441 attaaaatca ggagagcgca ttaaccagct cttttcgaca gatatcaaaa tcattcaaaa
    13501 tagagaggtt tttagctatt cggtggatag tgttctctta tcacgatttc cacgttttcc
    13561 taagaagggg ttgattgtag atttctgtgc tgggaatgga gcagtggggc tttttgctag
    13621 cactcgtact caagcacaga tattgtctgt tgagattcag gagcgtttgg cggatatggc
    13681 tgaacgctct gtccgtttga atggattaga ggagcaaatg caggtcatct gcgatgattt
    13741 gaaaaatatg cctgctcaca ttcaggggag taaggtggat atgattttgt gtaatccacc
    13801 ctatttcaag gtggatcctc attctaatct gaacgagagt gaacattatc tcttggctcg
    13861 acacgaaatc acgactaatt tggaagaaat ctgtcatagt gcccagagta ttctcaagtc
    13921 taatgggcgt ttggccatgg ttcatcgtcc tgatcgactt ctggatattt tggatacgtt
    13981 aaaacgacat aatctagccc ctaagcgcct gcagtttgtt tatccaaaaa gagaaaagga
    14041 agccaatatg cttttgattg aggcgatcaa ggatggctca acaagtggct ttaaggtctt
    14101 acctcctttg attgtccaca atgatgatgg ctcttatacg cccgaaatcg aagagattta
    14161 ttatggatca taaggcttat atgtacgttc tggagtgtcg tgatggatcc tactatatag
    14221 gctatacgac tgatgtgaga agacgcctcg ctatccacaa tagtgggaag ggagccaaat
    14281 atacacgagc acgcttgcca gtcaaactta tctatgctca aggttttgcc agtaaggaag
    14341 aagccatgtc ggctgaagct cttctcaagc gtaagaagag gccacagaag gaagaatttt
    14401 tatctgaaaa tcaagataga aatttactca gttattttga agaatcgtgg ggagtccttt
    14461 gactcctctt acctttgtca aaaagcgaaa aaaatgctac aataaagaaa ataaacaaaa
    14521 tgaggtatta tcatgtccaa gattctagta tttggtcacc aaaatccaga ctcagatgcc
    14581 atcggatcat ctgtagcttt tgcctacctt gcaaaagaag cttacggttt ggatacggaa
    14641 gctgttgccc ttggaactcc aaatgaagaa acagcctttg tcttgaacta ttttggtgtg
    14701 gaagcaccac gtgttatcac ttctgccaaa gcagaggggg cagagcaagt tatcttgact
    14761 gaccacaatg aattccaaca atctgtatca gatatcgctg aagtagaagt ttacggtgtt
    14821 gtagaccacc accgtgtggc taactttgaa actgcaagcc cactttacat gcgtttggag
    14881 ccagttggat cagcgtcttc aatcgtttac cgtatgttca aagaacatgg tgtagctgtg
    14941 cctaaagaga ttgcaggttt gatgctttca ggtttgattt cagataccct tcttttgaaa
    15001 tcaccaacaa cacacccaac agataaaatc attgctcctg aattggctga attggctggt
    15061 gtgaacttgg aagaatatgg tttggcaatg ttgaaagctg gtaccaactt ggctagcaaa
    15121 tctgctgaag aattgattga catcgatgct aagacttttg aactcaacgg aaataatgtc
    15181 cgtgttgccc aagtgaacac agttgacatc gctgaagttt tggaacgcca agcagaaatt
    15241 gaagctgcaa tgcaagctgc caacgaatca aacggctact ctgactttgt cttgatgatt
    15301 acagatatcg tcaactcaaa ctcagaaatc ttggctcttg gtgccaacat ggacaaggtc
    15361 gaagcggctt tcaacttcaa acttgaaaac aatcatgcct tccttgctgg tgccgtttca
    15421 cgtaagaaac aagtggtacc tcaattaact gaaagcttta atgcgtaaga ttttgggtgt
    15481 cagctcaaaa tcggaaagtc tagtttgcct tatatcgaaa ggagtttcgg ctcctttttt
    15541 tctaggagtg aagtatgtta gaaaatggcg atttgatttt tgtgagagat gggtcagaca
    15601 tgggacaggc catccagact tccacaggta actatagcca tgttgccatt tatttggatg
    15661 ggatgattta tcatgctagt ggacaggctg gtgttgtctg tcaagaaccg gcagacttct
    15721 ttgagtccaa tcatttatac gacctctatg tttacccaga aatggatatc cagtcggtga
    15781 aggaaagagc ttgcagacat cttggagcac cctacaatgc ttctttctat ccagatgcag
    15841 ctgctttcta ctgctcccag tatatagcag aaatcctacc tatttttgaa actattccta
    15901 tgaaatttgg agatggggaa caggagatta gtgatttttg gagggagtat tacatagaac
    15961 taggtctgcc tgttcctctg aaccaagctg ggaccaatcc tagtcagttg gcagcatcgc
    16021 ctctgttaca atgtaaagaa agggatcttc atgattcaga tttttaatcc atctcgtttg
    16081 acgagacagc catttttgga gaattgatcc gctatctgga ccagtatgag gatgtgattc
    16141 tacgggaaat taagtctcag tttccagatg ttgcagttga taaactcatg gaagagtata
    16201 taaaggcaag cttgattcta cgtgaaaata agcgctatta ccttaatttt cctacgcttg
    16261 aatcacttga tagtcttgaa ctggatcaag agatttttgt cagagaagct agtccggtct
    16321 atcaagcctt gttggagcag agttttgaga cggaattgcg caatcaaatc aatgcagcta
    16381 ttttagttga aaagacggac tttgcgcgca ttaaaatgac cctgtccaat tatttttaca
    16441 aggtcaaaca gcagtatcct ttgacagaaa aacagcagga gctctatgac attttaggag
    16501 atgttaatcc tgagtatgcc ctcaagtata tgacggcttt tttgttgaaa tttctcaaaa
    16561 aagaccagct tatgcagaaa tgccgtgata tctttgtgga cagtttggtt gtcttaggct
    16621 atattgtgca aaatgaagat agaaagtatg agttggctat cgattttgat aaggagagat
    16681 taactttcta cttagcgtga tttcttgttt ctgagcacat tgtttgactt tccttagtat
    16741 tcggtataaa ctatatgtaa ccggtaacac atatcggaat aaactaaagg agacaatcat
    16801 atgtcacttg aaaacaaatt ggaacaagca acaggcgctg tcaaagaagg ttttggtaaa
    16861 gttactggag acagcaagac agaacttgaa ggagctgttg aaaaaacagt tgctaaggca
    16921 aaagacgttg tagaagacgc aaaaggtgct gtagaaggtg ccgttgaagg tttgaaaaac
    16981 gtttttacta aataatagga aaaaatcaag ggtttcattt tcccttgatt ttttctattc
    17041 ttataaataa ttttctgcga cggctgtatc tcctgggtag gattctttct tgccctggat
    17101 gatttggtaa caatcggctc ccttacccgc aataataact gcatctaatt cgtgatttgt
    17161 gatagccatt gccgccttga tggcttcttg gcgatccgca atcttttcaa caggatgatt
    17221 gatgtagcta ctaatttcat ctgcaatggc cattgggtct tcatagttag ggtcatcagc
    17281 agtcagaaag acttgaatct cagggtgttg attgaggagg aggccaaagt ccttacgacg
    17341 actttctccc ttgtttcctg ttgatcccag aaccagagca atctttccgg tttgatgagt
    17401 ttcaaccaca ttgatgagtt ttttcagact atccccattg tgggcatagt cgatgaagac
    17461 cttggctcca tttttctgag tgaggacttc catacgacca ggaacgcggg ttgcagcgat
    17521 gccttttttg atgtcctcaa gacttgctcc gagacggaga caagcaagtc cagcagcaac
    17581 tgcattttct tggttgaagt tgccaatgag ttggatatca taatctccag cgagtttacc
    17641 cgtagctgaa aagctaaagg ctttggaatt ctcgatttgg ttatcaaatt ggctaccata
    17701 gaaatcatgg tcttgatctt caacctgttc tttcaagact gagaagtggt ccatgtcact
    17761 gttaatgatg actgctcggc tattttccat caagagacgc ttgtggtaga aatagtcttc
    17821 aaagctaggg tgttcaatcg ggccgatatg gtcaggagtg atgttaagaa agactcctac
    17881 atcaaaggtc agtccataga ctcgatggac tagataggct tggctagaga cttccattac
    17941 gagatggctt cttccattct taacagcttg agccatcatg tcaaagaggt cgatattttc
    18001 aggtgttgag aatgaagatt taaagaaagt tgtgccatcc aaagttgtat tcatggttga
    18061 taagagggcg gttgggtaac gttgagatag gatgttgtaa gcaaagtaag ctgctgttgt
    18121 cttaccctta gttcctgtga aggcgagaat tttgagtttc tcttgtggat taccatagaa
    18181 ctccatggca atcaaactca tggctttctt tatatcgttc acaatgatga cagggatacc
    18241 gacttcgtag tccttttcag ctacatacca agctaaacct tgtgttatag cagaaagaag
    18301 gtattctttt ttaaaggcag caccttttgc aaaaaaaaga gtgtcttctg ttacttttcg
    18361 gctgtcgtag ctgatgctat caaaaacaac tttgctgtag ttgtagtggt aatgaccttg
    18421 gtcaataatt tcgcgaaaaa ggccatcttt ctttaaaata tctaatacag tttcaatttt
    18481 tatcatactt tctattgtaa accgaaagtc gcaaatttac aagtaacaag gaaaagttta
    18541 taatggaaga taaggagttt ttcctagtta tcaaaattga atgaggaatc tatgtcgcac
    18601 gaaaacaatc accagcaggc ccagatgtta cgggggactg cttggctaac ggctagtaac
    18661 tttatcagtc gcctactcgg ggctgtttac attatccctt ggtacatctg gatgggggct
    18721 tatgcagcta aggcaaatgg tctctttacc atgggttaca atatctatgc ttggttcttg
    18781 ttggtttcaa cagcggggat tccagttgcg gtggccaagc aagttgccaa gtataatacc
    18841 atgcgagaag aagagcatag ctttgccctg attcggagct tcttaggctt tatgacagga
    18901 ctaggcctgg tttttgcttt agtcttgtat gtctttgctc cttggctagc agacttgtct
    18961 ggcgtgggca aagacttgat cccaatcatg caaagcttgg cttggggagt cttgattttc
    19021 ccgtctatga gtgttatccg aggatttttc caagggatga ataacctcaa accttatgcc
    19081 atgagccaaa ttgctgagca ggtcattcgt gttatctgga tgctcctagc aacctttatc
    19141 attatgaagc tcggttcagg agattatcta gcagccgtta cccaatcaac ctttgctgcc
    19201 tttgtcggta tggtagccag ttttgcagtc ttgatttatt tccttgccca agaaggttca
    19261 ctcaaaagag tctttgaaac aggagataag attaacagta agcgtctctt ggttgatacc
    19321 attaaggaag ccattccttt tatcctgaca gggtctgcca tccagctctt ccagattttg
    19381 gatcagctga cctttatcaa tagtatgagc tggtttacca actacagcaa tgaggacttg
    19441 gttgtcatgt tttcttattt ctcagccaat cctaataaaa tcacgatgat tttgatttct
    19501 gtaggggttt cgattgggag tgttggtttg ccacttttga cggaaaacta tgtcaagggg
    19561 gacttgaaag cggcttctcg tctcgttcag gacagtctca ccctactctt tatgttcttg
    19621 ctaccagcaa cggttggagt ggttatggta ggagaacctc tttatacggt cttctatggt
    19681 aagccagata gtttggctct gggcttattt gtctttgcag ttttgcagtc tattatttta
    19741 ggcttgtaca tggtcttgtc tccaatgctt caggccatgt tccgcaaccg caaggccgtt
    19801 ctctatttta tctatggttc tattgccaag ctagtcttgc aactacctac catcgccctc
    19861 ttccacagtt atggtccttt gatttcaaca accattgctc tcatcattcc taacgtcttg
    19921 atgtatcggg atatttgtaa agtaactggt gtcaagcgca aggtgatttt gaagcgaacc
    19981 attttaatca gtttgctgac cctagtcatg tttctgttaa taggaaccat ccagtggctg
    20041 ttaggatttt tcttccaacc aagtggacgt ttgtggagct tcttttatgt agctcttgtc
    20101 ggtgccatgg ggggtggact ttatatggtt atgagtctgc gtacctattt attagataag
    20161 gtaataggaa aagcccaagc agatcgcctg cgagcaaaat ttaagctttc gtaaggtagc
    20221 atttataaat aaaaggaata agttgaacaa tcttttagga gaacttgaaa cttattcctt
    20281 ttttagcgtc aaaatagcta aaattatctt tcaaaaatag aaaatgagtt ttttgatttt
    20341 ttggaaaaaa caattgacta aacaaaccaa tagttgtata ataaaacaaa tatttaaagc
    20401 aggaggttct ggaaatgaaa aagtctaaga gcaaatatct aaccttggca ggttttgtcc
    20461 tgggtacagg agttttattg agcgcgtgtg gaaattctag cactgcatca aaaacctata
    20521 actatgttta ttcaagtgat ccatctagtt tgaactatct agcagaaaac cgcgcaacaa
    20581 ccaatgatat tgtgaccaat ctggtagatg gtctcatgga aaatgaccaa tatgggaact
    20641 atgtgccatc cttggcagaa gattggactg tttctcagga tggtttgacc tatacctaca
    20701 aacttcgtaa ggatgccaag tggtttactt ctgagggaga agaatatgca cctgtaactg
    20761 cccaggattt tgtgacagga ttgcaatatg cagctgataa aaaatcagaa gccttgtatc
    20821 tagtgcagga ctctgttgca ggtttggatg actatatcac tggtaaaaca agcgactttt
    20881 caactgtcgg tatcaaggct cttgatgatc aaaccgttca atacaccttg gctcgaccag
    20941 aaccttactg gaactcaaaa acaacctcaa ccattctttt cccagtcaat gcagatttct
    21001 tgaaatcaaa aggggatgat tttggcaagg tagaccctgc taatattttg tacagtggac
    21061 ctttcttgat gaaagctttt gtttcaaaat ctgtcatcga atacaagaaa aatcctaact
    21121 actgggatgc taaaaatgtc tttgtagacg atgtgaaatt gacctactat gatggtagtg
    21181 accaagatgc tcttgttcgt aactttacag acggagccta tagctatgcc cgtctctatc
    21241 cgaatagttc aagttttgaa gggattaaag aaaaatacaa agatgatatc atctacagta
    21301 tgcaggatgc tacgtcttat tactggaatt ttaacctaga tagacaagct tataaattta
    21361 cttctaagac gaccgacatt gaaaagaaat caactcagga agcagttctt aataaaaact
    21421 tccgtcaagc tattaacttt gcctatgatc gtacctccta tggggctcaa actcagggag
    21481 aagacggagc gactaagatt ttgcgtaact tggttgttcc tccaaccttt gtaagtatca
    21541 aaggaaaaga ttttggtgaa gtagtagcct ctaagatggt caataattat ggtaaggaat
    21601 ggcaaggcat caactttgcg gatggtcaag acccttacta caatcctgag aaagccaagg
    21661 ctaaatttgc tgaggccaag aaagagctag aagctaaggg agttcaattc cctattcatt
    21721 tggatgcgac agttgaccaa gcttctaaga aggggattca agaagtaagc tccatgaagc
    21781 aatctattga agcagcttta ggtacggaga acgtcgttat tgatatccaa cagttatcaa
    21841 cagaggacta tgataactca agttaccttg ctcagactgc tattcagaaa gactacgacc
    21901 tttacaatgg tggttggagt cctgactact tagatccatc aacctatctt gatatcttta
    21961 gtgtcaagaa tggtggggtt ctacaaaatc ttggactcga ccctggtgaa gccaatgaca
    22021 aggctaaggc agttggactt gacacttata ctcaaatgtt ggaagaggct aataaggagc
    22081 aagacccagc caaacgttat gagaaatatg ctgatattca agcatggttg atagatagtt
    22141 ctctagcgat tccaaatgtt tcattaggtg gaacgcctag cttgagaaaa acagttcctt
    22201 tctcagcacc ttattcattg gctggtaata aaggggttga atcatataaa tacctcaaag
    22261 tacaagataa gattgtcaca acagacgaat atgcaaaagc cagagaaaaa tggttgaaag
    22321 aaaaagaaga atccaataaa aaagcccaag aagaattggc aaaacatgtc aaataaaatc
    22381 taattgtaga taagtttgtg taagaagtct ttgtgcttaa aaacgcataa tatcaggtat
    22441 ataaaatcct agatgttatg cgttttgtta taggaagatt tattagattt tatcctcaaa
    22501 ttgagttatt cccgacttta tccgttgaaa tattataagg agtatttatg aaattaaaat
    22561 tattaagagt agatactaag gtgattatgt ggagtttctt acttgttctg tctagtctac
    22621 ttgctttgtt gcttcccctt atcttaaagg gtttaataga tgggagttct attgaaaata
    22681 taggttccaa agtatttcaa tcgtttttga tttttattgg tcaagccttg ttttcttcta
    22741 ttggttacta tctgtttagt caatcgggtg aaaaaagata gcaaaaatca ggaaaaaagt
    22801 gatagagggg ttgatttatg cagagaaatc cttctttgat aagagccaaa gtggggagtt
    22861 gacttctgcc attgtcaatg acatgagtgt cattcgtgag tttttaatta cgactttccc
    22921 aaatattatt ctgagtttag ttatggtact tggttccatt gtagtcttat ttagtcttga
    22981 ttggaatctt tctctacttt tattcatcac tcttccttgt atgatgttta ttatcttgcc
    23041 cctttccaat atcagtgaaa agtatagtcg tcgtttacag gaggaaatcg gatttttaac
    23101 agggcaattg actgaaaaga ttcaagaaca tgaattaatt aagactaacc aagcagagaa
    23161 aagtgtacag gatgttttgg ataattgtat tgaaagggta caaaacaatt cactgaaatc
    23221 agatagggtt acttcttttg agaccccgtt tgctctctta tttatctttg cgactatagt
    23281 tgtgatgcta acctatgggg gttatcgggt cagcgcagga tatatatctg tgggaacctt
    23341 ggtttcgttt ttgatttacc tctttcaatt acttaatcct attagtaata tagctaattt
    23401 tgtaactatt tattctagta gcaagggatc ttcagttgca ctggagaact tgcttgcagt
    23461 tcctaaagaa aaatttgagg gaggaaaatc ggtatcagga caagggttga attttaacca
    23521 tgtctatttt ggttatgatg aaaatcgacc tgtcttaaag gatattactt gttcaatttt
    23581 caaggggcaa aaaattgctt ttgttggacc atctggatca ggaaaatcaa cgattgtgcg
    23641 tttgttagag cggttttata aaccgctttc aggagatatt ctaatggagc aatcaagtat
    23701 atatgatttt aacttaaaag aatggagaag taaaatcgct tgggtttcac aaaataatgc
    23761 agtcttatct ggcagtattc gtgacaatct ttgtctcggt ttgaatcgct tagtaactga
    23821 tgatgaattg atgaaagtgc tagacttagt atcactaggt gatgagattc gctccatgaa
    23881 agagggacta gatactgaag ttggtgaacg cggacgattc ttgtcagggg ggcaaagcca
    23941 aagacttcaa atagctagaa cctacttaaa agatgctgaa attcttatat ttgatgaagc
    24001 cactgctaat cttgatgcgg attctgagta tgcgattatc agtagcctct attctgtatt
    24061 aaaggagaag acggttgtga ttatagcgca tagtttgtcc acggtaaaag atgtggattg
    24121 tattttcttc ttagaggagg ggaaaatcac tggctcagga actcataagg aactactgga
    24181 aaatcatgag cgttatgctc gttttgtgca ggagcaaatg atagagtgaa ggtgtctttt
    24241 gagattcacc attttatagt ctattaaagg gagcaggaaa aactcccttt ttatatagtt
    24301 tgaaactata actagctctt gaaaagaaga aaatgagttg atgaaaataa gtggtacaat
    24361 agttactata gatttggagg tattgtatga gcaaggaatt acacattaac acaattttgg
    24421 cccaggcggg tattaagtca gatgaggcaa caggtgcttt ggtgacacca cttcattttt
    24481 caacgaccta tcagcatcca gagtttggtc gatctactgg gtttgactat acgcgcacta
    24541 aaaatccaac tcgtagtaag gctgaggaag tcttggcggc tattgagtca gcagactatg
    24601 ccctagcgac tagctcaggg atgtcagcta ttgtactggc ctttagcgtc tttccagtag
    24661 gaagtaaggt cttggcagtg cgtgatcttt acggtggttc ttttcgctgg tttaaccaag
    24721 tggagcagga aggtcatttc cattttacct atgccaatac agaagaagag ttgattgccg
    24781 agttagaaaa ggatgtggat gttctctata tcgaaacccc aaccaatccc ttgatgttgg
    24841 aatttgatat cgaaaaacta gcaaaattgg ctcatgctaa gggtgccaaa gtggtggtgg
    24901 acaatacctt ctatagccct atctaccaac gtccgattga agatggagca gatatcgttc
    24961 tccattcagc aaccaagtat ctagcaggcc acaatgatgt cttggctgga gtggttgtga
    25021 ccaatagttt agaactatac gagaagcttt tttacaatct caatacaaca ggggcagtct
    25081 tgtctccatt tgacagctac cagttgcttc gtggtctcaa gaccttatct cttcgtatgg
    25141 agcgctcaac agctaacgcc caagaagtgg ttgccttttt gaaggattct ccagcagtta
    25201 aggaagttct ctacactggt cgtggaggca tgatttcctt taaagtagcc gatgaaacac
    25261 gcattcctca tattttgaac agtctcaagg tcttctcttt tgcggaaagt ttgggcggag
    25321 tggaaagtct tattacttat ccaacgactc aaactcatgc tgatattcca gcagaagtac
    25381 gccattctta tggtttgaca gatgacctct tgcgtttgtc tattgggatt gaggatgcta
    25441 gagatttgat tgcagatttg cgccaagcct tagaaggata agacaaagat gggaaaatat
    25501 gattttacaa gcctgcccaa ccgtttaggg caccatacct ataaatggaa agaaacagaa
    25561 acggatagtg aagttctacc agcttggata gcggatatgg actttgtggt cttgcctgaa
    25621 atccgccaag ccgtgcaaac ttacgcagac caactggttt atggttatac ctatgccagt
    25681 gaagacttaa ttaaggaagt tcaaaagtgg gaagctacac aatacggtta caactttgac
    25741 aaagaggctc ttgtctttat cgagggtgtg gtaccagcca tctcaacagc tattcaaacc
    25801 tttacaaaag aaggcgaggc ggttttaatt aacacgcctg tctacccacc ctttgctcgc
    25861 agtgtcaagt tgaataatcg tagattgatt actaattcct tagtggaaaa ggatagtctg
    25921 tttgagattg actttgacca acttgaaaag gatttggtgg aagaggaggt taaactctat
    25981 gttctttgca accctcacaa tcctggtgga cgtgtttggg aaaaagaagt gttggagaag
    26041 attggccaac tctgccaaaa acacggtgtt ttgttagttt cggatgagat tcaccaagat
    26101 ttgaccctct ttggtcacaa acaccagtct ttcaatacca tcaatcctgc cttcaaaaat
    26161 tttgctatcg tcttgagcag tgccactaaa acatttaata ttgctggaac aaaaaattcc
    26221 tatgcagtca ttgaaaatcc taagttgaga ctggctttcc agaaacgcct gttggccaat
    26281 aatcagcatg aaatttcagg cttgggttat ttggcgacag aagctgccta tcgatacggt
    26341 aaagattggc tagaggaact caagcaagtc tttgaagacc acatcaatta tgtgatggat
    26401 ctatttggaa aagagactaa aatcaaggtc atgaaaccgc aaggtaccta cttgatttgg
    26461 cttgactttt cagcttatga cctgactgat gaaacattgc aagagttgtt gagaaatgaa
    26521 gccaaggtta tcctcaaccg tggtttggat tttggagagg aaggaagtct ccatgcccgc
    26581 atcaatatag ctatgcccaa atctctgttg caagaagtct gtcagcggat tgtggctact
    26641 tttgccaaac gttaaaaatc cagccttcta ggagaaaagt cttcctagaa ggctattttc
    26701 ataggcgaaa atatggtata ataaaaagat aaggtaaagg tgaaaatatg gctaaattga
    26761 ttccggggaa agttcgtatc gaaggtgttg ccctttatga aactggtaag gttgatatca
    26821 tcaaggaaaa gaacaatcgg ctctacgctc gcgttgcaga agaagaactg cgctatagtt
    26881 tagaggatga tttggttttt tgtgcctgtg atttttttca aaagaggggt tactgtgtgc
    26941 atttggcagc gctagagcat tttctgaaaa atgatgagcg tggtcaggaa atcttgtgga
    27001 gtctggaaga aggtcatgaa gaaaaagagg ccgttgaaac caaggtgacc ttgggtggca
    27061 agtttttgga tcgaatttta tctccaaaat cagaatgcgc ctatgagtta tcagctgtgg
    27121 gtcaggtgga agcaggaacc aatcatatct tgtggactct gagaatcggc caaatcaata
    27181 gccaaaaata ctatgtcatt cgggatattc cacttttttt aaggattgtc gagcagagaa
    27241 agtcgtatat gattggcaag atttatgagg agtctctttc ttgggaagcc tttgatgatg
    27301 ccagccaaga acttttgact ttcttgcacg gactaacgga ggaagggctg gtttcagacc
    27361 tctttttcca aaaccaaggt cggcacctct ttttccctct gacctttttt gagcagggtg
    27421 tgaatttact gatggccttg ccccattttc aatttgacca tcaagtggat agctaccaaa
    27481 ccctgctttt tcaggatatg catgctgatg ccaatctatt tgcctttaca gtaacagaat
    27541 actcggacta ttttgaaatg gaaatcagtg agagtcctag ggtcaatgtc ttttatcagg
    27601 gagcagtact tttccataaa ggtcaggttt attttttaac agaccagcag atgcgtcttc
    27661 tcaaggaaat taaagcgtta cctgtgggtc aacaaggaaa gaaatacctg caatttgata
    27721 gcagtgatcg agacaaattg gcctcctgtc tgactctttt tatccagatg ggcaccgttt
    27781 cagctccaga acgtctacaa atcaaaactt ttgcgccctc tttttacttt gacagggaag
    27841 aagataatcg gattcgtttg gaaattcagt ttgattatgg aaatagacag gtatctagcc
    27901 gacaagagct agaagaatta ccattttcaa gtgacgcaga cttagaagaa agaattttcc
    27961 aagtctgttt ggctgcgggc tttgaagccg attttcaatc ttggcgtcag gccttaaaag
    28021 cggagtctgt ctatcatttt tttcatgata tcattccagt ctttgaaaaa ctcgggcatg
    28081 ttgacctatc agataaacta gaagagcttt atagcctagc aagtcctcag gtgcagattg
    28141 cctccaaggg aggtctcttg gaaatccagt ttgattttca agatattgcc caggaggaaa
    28201 tcgaccaagc catgcaggcc ttggttgcca atcaggattt ttatattgat tcgtctaatc
    28261 aagtttactt tttcgatgaa gaaaccaaga aaattcgcca aaatctacag gaactggggc
    28321 aatttgaatt aaaagatggg accttgcagg ctcggaaatc cttggcctac agtttagctc
    28381 atctctttga agggcgagac cgtgtttctt tttcacaaga attccagaat ctggcccagg
    28441 atttgacaca tccagaggac tttcctcgac aggcaactca ggttcaggct gacttgcgag
    28501 attatcagga aaagggaatt ggctggttgc agatgctcca tcattatggt tttggtggga
    28561 ttttggctga tgatatggga cttgggaaaa cccttcagac cattgctttt ttgactagtc
    28621 aagtgacaaa agaaagtcgg gttttgattc tcgctccgtc aggtttgatt tacaactggg
    28681 cagatgagtt tcagaaattt gccccacagt tggatgtggc tgttgttcat ggtttgaaag
    28741 caagtcgtga ggagattctt gccgagagcc atcaaatcta tgtgactagc tatgccacct
    28801 tccgtcagga cagtgagttt tatcagggga tggcctttga cttccttttc ttagatgagg
    28861 ctcaggtcat gaaaaatgcc cagaccaaga ttgcccagac cttgagacaa tttgtggtgc
    28921 cgtcggtctt tgccttgtca ggaactccga ttgaaaacca tctgggtgag ttgtggtcta
    28981 ttttccaaat cgtcatgccc ggacttttgc caagcaagaa agaatttatg aaattgccag
    29041 cagagcgagt ggctcagttt atcaagcctt tcgtgatgcg acgcaagaaa gaagaagttc
    29101 tgactgaatt gccagacttg attgaggtgg tttataaaaa tgaactggaa gaccagcaaa
    29161 aggctattta ccttgcccag ttacaacaga tgcgagacca tctggctcaa gtgtcagaac
    29221 aggaatttca gcgaagtcgt gtggaaattt tatctggttt gatgcgcttg cgtcaaatat
    29281 gtgacactcc tgccctgttt atggaagatt atcagggagc cagcggcaaa ctagatagtc
    29341 tccgagacct actggtacag gtggcagacg gcggacaccg tgtcttgatt ttctctcagt
    29401 tcaagggaat gttggaaaaa attgaacaag aactgccaga cttgggcctg acatccttta
    29461 aaattacggg ttcaacccca gccaaggaaa gacaagacat gaccaaggcc tttaaccaag
    29521 gagaaagaga tgcctttctg atttccctca aggctggtgg ggtcggtctg aacctgacag
    29581 gtgcagatac agtgatcttg gttgaccttt ggtggaatcc tgcggtggaa gcgcaagcca
    29641 ttggccgtgc ccatcggatg ggtcaggaag aaacggttga ggtctatcgc ttggtgacca
    29701 agggaaccat tgaagaaaaa attcaggaac tccaagaaca aaagaaacat ctggtgtcac
    29761 aagtattgga tggcacagag tcacgtggta gtctgaccct agcagaaatt agagaaattt
    29821 tgggaatttc tgaagccagc acttgaaaaa tcaagacaat acgctataat gaagtgttga
    29881 aaggaaatag aaaatgaaac aagaacgatt tccattggtg tcagatgacg aggtcatgtt
    29941 gactgaaatg ccagtcatga atctctatga tgagtctgat ctgatcagta atatcaaggg
    30001 tgagtatcga gataaaaatt atttagaatg ggctcctatt actgaagaaa aaccagtaaa
    30061 accgattgaa aagcaagtcg aaaaacctaa aaaggctcct ttaggggtta aaaaagaagg
    30121 aaagagctat gcggaggtgg cgcgtgaaga agcgcgtgcg gacttgaaaa agaaacgctc
    30181 tgctaactac ctaactcagg atttcagcct tgcgagacgt cattctcagc ccagtctagt
    30241 tagacagggc aatcaaccga caactccttt ccaaaaggaa aatcctggtg aatttgtcaa
    30301 atatagccaa aaattgaccc agtctcatta tatcttggcg gaagaagttc attctatccc
    30361 taccaagaat gaagaagtgt cagcacctgc tccaaagaaa aacaattatg attttctaaa
    30421 gaagagccaa atctacaata aaaaaagtaa acaaacagaa caagaacgtc gggttgccca
    30481 agagttgaat ctgaccagaa tgacagaata ggggagaaaa catgtcaaag acatatcatt
    30541 ttatcggaat taagggatca gggatgagtg ccttggcctt gatgttgcac cagatggggc
    30601 acaaggttca gggatcagat gttgaaaagt actactttac ccaacgcggt cttgagcagg
    30661 caggaattac cattcttcct tttgatgaaa agaatctaga cggtgatatg gaaattatcg
    30721 ctggaaatgc ctttcgtcca gataacaacg tcgaaattgc ctatgcggac caaaatggta
    30781 tcagctacaa acgttaccat gagtttctag gtagctttat gcgtgacttt gttagcatgg
    30841 gagtagcagg agcacatgga aaaacttcaa cgacaggtat gttgtctcat gtcttgtctc
    30901 acattacaga taccagcttc ttgattggag atgggacagg tcgtggttcg gctaatgcca
    30961 aatattttgt ctttgaatct gacgaatatg agcgtcactt catgccttac cacccagaat
    31021 actctattat caccaacatt gactttgacc atccagatta tttcacaagt ctcgaggatg
    31081 ttttcaatgc ctttaacgac tatgccaaac aaattaccaa gggtcttttt gtctatggtg
    31141 aagatgctga attgcgtaag attacgtctg atgcaccaat ttattattat ggttttgaag
    31201 ctgaaggcaa tgactttgta gctagtgatc ttcttcgttc aacaactggt tcaaccttca
    31261 ccgttcattt ccgtggacaa aacttggggc aattccacat tccaaccttt ggtcgtcaca
    31321 atatcatgaa tgcgacagcc gttattggtc ttctttacac agcaggattt gatttgaact
    31381 tggtgcgtga gcacttgaaa acatttgccg gtgttaaacg tcgtttcact gagaaaattg
    31441 tcaatgatac agtgattatt gatgactttg cccatcatcc aacagaaatt attgcgacct
    31501 tggatgcggc tcgtcagaaa tacccaagca aggaaattgt agcagtcttt caaccgcata
    31561 cctttacaag aaccattgcc ctgttggacg actttgccca tgctttaaac caagcagatg
    31621 ctgtttatct agcgcaaatt tatggctcgg ctcgtgaagt agatcatggt gacgttaagg
    31681 tagaagacct agccaataaa atcaacaaaa aacaccaagt gattactgtt gaaaatgttt
    31741 ctccactcct agaccatgac aatgctgttt acgtctttat gggagcagga gacatccaaa
    31801 cctatgaata ctcatttgag cgtctcttgt ctaacttgac aagcaatgtt caataggatg
    31861 ttcccatgga aattccaatt aagatcattc aggcaagcaa gtttgatttg cctgagatag
    31921 gggcacttca gacctcgtct tttccagctg aaaagcagca actttcccat attttagaag
    31981 aaagtatccg taagtgtgcg gatacctttc ttctagctag ggatgaaaat caacttttag
    32041 gctatatttt atcaagtccc cagtcagaca atccgcaatg tctaaaagta cattctttag
    32101 tcatcgagtc tgaccatcag agacagggcc tgggaacact tcttcttgca gccttgaaag
    32161 aggtggcagt tgagctggat tacaaaggga ttcgtttgga gagtcctgat gagctgcttt
    32221 cctattttga aatgaacggt tttgttgatg aagaagaaac tttgctctat gcaactagcc
    32281 agggctatag tatgatttgg tttaatccct tttatctgga ggaacaatga aaatcagaca
    32341 agcaagatta gaagatttgg atcggattgt tgaacttgaa tttgaaaatt tttcggtcga
    32401 agaagccatt cctccttctg tctttgaagc acatttgaga gaaattcaga cctcttttct
    32461 ggttgctgaa aaagaaggaa gaatcatggg ttatatcgaa ggaccagttg gcctgcaccg
    32521 ccatctgcaa gaccagtctt ttacagaaga aataaaagac tatagtcatg agcctggtgg
    32581 ttatatctct gtgacctgtc tgtctattgc caaggaggca cagggactcg gactgggtca
    32641 gaaattgctg acagccttga aagaagttgc tcttgaagat gagagagatg gcattaatct
    32701 aacctgtcat gactatctca tcgcctatta tgaaaaacat ggatttgtca acgaaggcca
    32761 gtcccagtca acctttgcag gggaaacatg gtatgatatg gtctgggaaa tgaaaaaata
    32821 agttaggaaa agtatcatag attgcttttt ttggactttt aagatataat attatggatt
    32881 atcaacaagg aggaaaaact tttgagtgaa aagtcaagag aagaagagaa attaagcttt
    32941 aaagagcaga ttctgagaga tttagaaaaa gtaaaaggct atgatgaagt tctgaaagaa
    33001 gatgaggcag tagttcgcac tcctgcaaat gaaccttcag ctgaagaact catggctgat
    33061 tccttgtcaa cggtagagga gattatgaga aaagctccta ccgtgcctac tcacccaagt
    33121 caaggtgtac cagcttctcc agcagatgag agtcaaagag aaactcctgg tgttccaagt
    33181 catccaagtc aagatgtacc ttcttctcca gcggaagaaa gtggatcaag accaggtcca
    33241 ggtcctgtta gacctaagaa acttgaaaga gaatacaatg aaaccccaac aagggtagct
    33301 gtttcctata cgacggcaga gaaaaaagca gaacaagcag gtccagaaac acctacgcct
    33361 gctacagaaa tagtggatat catcagtgat acatcacgtc gtagccgtag agaaggagca
    33421 aaacccgtta agcctaagaa agagaagaag tcacatgtga aagcttttgt gatttcattc
    33481 cttgtattcc ttgccttgct ctcagcaggt ggttacttcg gttaccagta cgtgctagat
    33541 tctttgttac ctatcgatgc taattctaag aaatatgtga cggttggaat tccagaaggt
    33601 tcaaacgttc aagaaatcgg tacgacgctt gaaaaagctg gtttggtaaa gcatggtctg
    33661 atttttagtt tttatgccaa gtataaaaat tataccgact tgaaagcagg ttactacaat
    33721 ttgcaaaaga gtatgagtac agaagactta ctcaaagagt tgcaaaaagg tggaacagat
    33781 gaaccgcaag aacctgtact tgcgactttg acaattccag aaggttatac cttggatcag
    33841 attgctcaag ctgtgggtca attgcaaggt gacttcaaag agtctttgac agcggaggct
    33901 ttcttggcta aagttcaaga tgagacgttt atcagtcaag cagtagcgaa atatcctact
    33961 ttactggaaa gtttgcctgt aaaagacagc ggtgcgcgtt atcgtttgga aggatacctt
    34021 ttcccagcta catactctat caaggaaagc acaactattg agagcttgat tgatgagatg
    34081 ttagctgcta tggataagaa cctatctcct tactatagta ctatcaaatc taaaaatttg
    34141 actgtcaatg agttgttgac cattgcttcc ttggtcgaaa aagaaggtgc caagacagaa
    34201 gatcgtaagc tcattgcagg tgtattctac aatcgtttaa atcgtgatat gccacttcaa
    34261 agtaatattg caatcttgta tgcccaagga aaactggggc aaaatatcag tctagctgag
    34321 gatgttgcga ttgataccaa cattgattca ccttataatg tttataaaaa tgtaggtctc
    34381 atgcctggtc cagtcgatag tccaagtctg gatgcgattg agtcaagcat caatcaaact
    34441 aagagcgata acctctactt tgtagcagat gtcacagaag gcaaggtcta ctatgctaac
    34501 aatcaagaag accacgaccg caatgtcgct gaacatgtca acagcaaatt aaactaaaca
    34561 aactaaaatt atgtgatacg tcacataatt ttctttagaa aatattatca gaagaaagtt
    34621 gagaaaaatg gcagaaaaaa catatcctat gacccttgag gaaaaggaaa aacttgaaaa
    34681 agaattagaa gaattgaaat tggttcgtcg accagaagtg gtagaacgca ttaagattgc
    34741 ccgttcatac ggtgaccttt cagaaaacag tgagtacgaa gcagctaagg atgaacaagc
    34801 ctttgtcgaa ggacaaatct ctagcttaga aacaaaaatc cgctatgctg aaatcgtcaa
    34861 tagcgacgca gttgcccagg acgaagtagc gattggtaaa acagtcacca tccaagaaat
    34921 tggtgaggac gaagaagaag tttatattat cgtaggttca gctggtgcgg atgcctttgc
    34981 aggtaaggtt tcaaatgaaa gcccaattgg gcaggccttg attggcaaga aaacaggtga
    35041 cacagcaacc attgaaacgc ctgttggtag ctatgatgta aaaatcttga aggttgaaaa
    35101 aacagcctaa aaacagaaaa aggagtgggg aggcgatgtg cttcactcac tcctttttcc
    35161 attttgctat tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttgc cgtatgtatg
    35221 gttactgact ttgtcagttt catctacaac ctcaaaacca tgttttgagc tgacttcgtc
    35281 agttctatct acaacctcaa aacagtgttt tgagcaacct gcggctagtt tcctagtttg
    35341 ctctttgatt ttcattgagt attagatgta tagtgcattg aagttaaaat agtaaacttt
    35401 gatttctaag acattattag aaattagatt aaattcctta atcgatttgc gcatgtttta
    35461 tttcatttca ttatacttta gattggaaaa taaggaatca cataaatcgc aagaaatagg
    35521 gaatctgatt cgtgtttata accgttcaaa aagggaagag gctgaaagtg agccacttaa
    35581 tctttatgtc gaagatgaaa agggcaatct ccttgcgggt ttgatagcag agacttttgg
    35641 aaattggcta gaaatcgagt atttgtttgt aaaagaggaa ctgcgagggc aaggaatcgg
    35701 ttcaaaacta ttgcaacagg cagaaagtga agctaagaat cgaaattgtt gttttgcctt
    35761 tgtcaatact tatcagttcc aggcaccgga cttttatcag aaacatggct acaaggaagt
    35821 tttttctttg caagactatc tctacattag gcaaagatat tattaccaaa agaatctgta
    35881 aggtgagtat ggaggtataa tacaaagaga ggctcgcaca taagtatgga ggtgtactga
    35941 tgtatatgag taactatcga taaataccag ttataaccta gaaattgtgt ctttctagac
    36001 gatattgagg acaatataat cgtagctcca aaattaggaa tcaaggctta tcaggttaag
    36061 aaaagaagtg atgttgttga tattttaaaa caatttattt aaactaaaaa ctctctatct
    36121 ttttaaattg acattaatcc gagattcccc tctaggattt tgtgttgctt tcattaaatt
    36181 tacaggtaag acttgctagc ttcagtaaat atacacaagt ttttcagaat agagtgaaat
    36241 ccgaaagaaa atggaaataa tgaaaactct tgtaggcata agaaaacacc tctgtgttat
    36301 acttgttgtt caaccacaaa cacaagaaag gcacagaaat gcaagacaat tatactacaa
    36361 aagccaaaca tttgacaatc gatagccgtc gcttaatcga aagatggaaa aaagaaggga
    36421 aatcaaatag agaaattgcc tctctacttg gaaaagctcc tcaaactatc cacactgaaa
    36481 tcaagcgtgg gacagtccga caatgtcttg gaaaagggcg cttcaaagag gtttattctg
    36541 ccgactatgc tcaacagtct tatgaaaaca atcgcaagcg ctcggtcaag aaatcaagcg
    36601 tgac
//
LOCUS       DAVLDI010000017        35839 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLDI010000017 DAVLDI010000000
VERSION     DAVLDI010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35839
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.017"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(279..1913)
                     /locus_tag="VXD01_000837"
     CDS             complement(279..1913)
                     /locus_tag="VXD01_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601266.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEIPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALAGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVTLVMVVAVHFLAQTTVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(1894..2643)
                     /locus_tag="VXD01_000838"
     CDS             complement(1894..2643)
                     /locus_tag="VXD01_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601267.1"
                     /translation="MIEFQNVSKLYGDKKALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            2822..4276
                     /locus_tag="VXD01_000839"
     CDS             2822..4276
                     /locus_tag="VXD01_000839"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV0601268.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVHSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4366..6984)
                     /gene="alaS"
                     /locus_tag="VXD01_000840"
     CDS             complement(4366..6984)
                     /gene="alaS"
                     /locus_tag="VXD01_000840"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV0601269.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNHNASQLSSKLVAIVADNAEVEAVSEGTTSLIFAETPFYAEMGGQVA
                     DHGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(7006..7491)
                     /locus_tag="VXD01_000841"
     CDS             complement(7006..7491)
                     /locus_tag="VXD01_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV0601270.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(7766..8005)
                     /locus_tag="VXD01_000842"
     CDS             complement(7766..8005)
                     /locus_tag="VXD01_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601271.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILSHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(8250..9320)
                     /locus_tag="VXD01_000843"
     CDS             complement(8250..9320)
                     /locus_tag="VXD01_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0601272.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9317..10090)
                     /locus_tag="VXD01_000844"
     CDS             complement(9317..10090)
                     /locus_tag="VXD01_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0601273.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(10087..10893)
                     /locus_tag="VXD01_000845"
     CDS             complement(10087..10893)
                     /locus_tag="VXD01_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0601274.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWIMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10874..12031)
                     /locus_tag="VXD01_000846"
     CDS             complement(10874..12031)
                     /locus_tag="VXD01_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601275.1"
                     /translation="MKKSIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRNIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(12192..13097)
                     /gene="murB"
                     /locus_tag="VXD01_000847"
     CDS             complement(12192..13097)
                     /gene="murB"
                     /locus_tag="VXD01_000847"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV0601276.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(13209..13961)
                     /locus_tag="VXD01_000848"
     CDS             complement(13209..13961)
                     /locus_tag="VXD01_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV0601277.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(13971..14702)
                     /gene="budA"
                     /locus_tag="VXD01_000849"
     CDS             complement(13971..14702)
                     /gene="budA"
                     /locus_tag="VXD01_000849"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV0601278.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIGEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            14844..16115
                     /locus_tag="VXD01_000850"
     CDS             14844..16115
                     /locus_tag="VXD01_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV0601279.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(16135..16950)
                     /locus_tag="VXD01_000851"
     CDS             complement(16135..16950)
                     /locus_tag="VXD01_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0601280.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(17107..17760)
                     /gene="phoU"
                     /locus_tag="VXD01_000852"
     CDS             complement(17107..17760)
                     /gene="phoU"
                     /locus_tag="VXD01_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0601281.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(17772..18530)
                     /gene="pstB"
                     /locus_tag="VXD01_000853"
     CDS             complement(17772..18530)
                     /gene="pstB"
                     /locus_tag="VXD01_000853"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0601282.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(18543..19346)
                     /gene="pstB"
                     /locus_tag="VXD01_000854"
     CDS             complement(18543..19346)
                     /gene="pstB"
                     /locus_tag="VXD01_000854"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0601283.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(19357..20241)
                     /gene="pstA"
                     /locus_tag="VXD01_000855"
     CDS             complement(19357..20241)
                     /gene="pstA"
                     /locus_tag="VXD01_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0601284.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(20231..21148)
                     /gene="pstC"
                     /locus_tag="VXD01_000856"
     CDS             complement(20231..21148)
                     /gene="pstC"
                     /locus_tag="VXD01_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0601285.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGIWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(21148..22026)
                     /gene="pstS"
                     /locus_tag="VXD01_000857"
     CDS             complement(21148..22026)
                     /gene="pstS"
                     /locus_tag="VXD01_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV0601286.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(22600..23904)
                     /locus_tag="VXD01_000858"
     CDS             complement(22600..23904)
                     /locus_tag="VXD01_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV0601287.1"
                     /translation="MQFPEGFVEKYKEILGDEARNFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKSSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(23905..24678)
                     /locus_tag="VXD01_000859"
     CDS             complement(23905..24678)
                     /locus_tag="VXD01_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV0601288.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(24668..24946)
                     /locus_tag="VXD01_000860"
     CDS             complement(24668..24946)
                     /locus_tag="VXD01_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV0601289.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(24946..25347)
                     /locus_tag="VXD01_000861"
     CDS             complement(24946..25347)
                     /locus_tag="VXD01_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV0601290.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(25557..26174)
                     /locus_tag="VXD01_000862"
     CDS             complement(25557..26174)
                     /locus_tag="VXD01_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV0601291.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(26164..26937)
                     /locus_tag="VXD01_000863"
     CDS             complement(26164..26937)
                     /locus_tag="VXD01_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV0601292.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRGIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(26948..27685)
                     /locus_tag="VXD01_000864"
     CDS             complement(26948..27685)
                     /locus_tag="VXD01_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV0601293.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSVVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(27690..28820)
                     /locus_tag="VXD01_000865"
     CDS             complement(27690..28820)
                     /locus_tag="VXD01_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV0601294.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(28904..29293)
                     /locus_tag="VXD01_000866"
     CDS             complement(28904..29293)
                     /locus_tag="VXD01_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV0601295.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(29309..29692)
                     /locus_tag="VXD01_000867"
     CDS             complement(29309..29692)
                     /locus_tag="VXD01_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV0601296.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(29693..30481)
                     /locus_tag="VXD01_000868"
     CDS             complement(29693..30481)
                     /locus_tag="VXD01_000868"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV0601297.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGVLVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(30474..31409)
                     /locus_tag="VXD01_000869"
     CDS             complement(30474..31409)
                     /locus_tag="VXD01_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV0601298.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(31539..31715)
                     /locus_tag="VXD01_000870"
     CDS             complement(31539..31715)
                     /locus_tag="VXD01_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV0601299.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(31855..32562)
                     /locus_tag="VXD01_000871"
     CDS             complement(31855..32562)
                     /locus_tag="VXD01_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV0601300.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESNLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            32713..33741
                     /gene="queA"
                     /locus_tag="VXD01_000872"
     CDS             32713..33741
                     /gene="queA"
                     /locus_tag="VXD01_000872"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV0601301.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            complement(34402..35529)
                     /locus_tag="VXD01_000873"
     CDS             complement(34402..35529)
                     /locus_tag="VXD01_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0601302.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFTTEYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNASGELAVNTSIDGYRVNDNGEWVR"
BASE COUNT        10698 a         8170 c         6761 g        10210 t
ORIGIN      
        1 ataatttcac ctatctgcat cattctattt cgaattctaa atatatgttc tatcaagaat
       61 acttggaaca cacacattat agtaattaac gtttttgaaa ttgaaaaata tccaaataaa
      121 taaactataa acaacaaaaa tagaactatg ttatatttct tattcaaaac attcctccct
      181 atatttttga ttaccaatct taatcattta caactacatt ctaacaaact ataaaagcgt
      241 ttgtcgaatt gaatttatca agcaagcgac caaccagctc atcttttttc tatttctgcc
      301 aatatgcgtg acaggtaata atgatagcca aaaatagcaa gagcaagcag gaggataaga
      361 gctcctactc ccaagctgat ggcaaggata gtggagagag actgaaccaa gaatatgctc
      421 ccaattacaa gggccatcag gattgcacta taaataaaca ataaaactat ggcgactatg
      481 ccatttgaac gattcaccag gtccgtaatg ctactccaat tggttgacag atttttaacg
      541 tccttaaagt aatggtggca agaaaggatg acactggcaa ggatccatgc cacaataagg
      601 taaatcatcg aaatgatggg caagcctaga tatagagaaa gaccaagcaa agtcagaact
      661 ggtaaaaagg actggacagc atatataatc caaaatttca ctttcacata acgagcaaag
      721 tcaaagggta aactcttaag aaaatcaaca ttttccctct ccaaggacaa ggcaattgaa
      781 tgcaggctgg tgatattgtt attgacaact gctataaaca ctcctacaaa aaacaagggt
      841 aaccagtatg gaggatgaat gtctggaact atctgagaat ctcggatttt ggaaatcaga
      901 ccgatcatca tgagataagg aaagaaagca cttgtaaaaa gcactgtaac cacgccagta
      961 ccctgtccca agagggtgag gtggtagcgt aaaaccatgc ggaaaaatcc ctttttagtg
     1021 gttgaaattc tctccttgct gcgacgttct tttttgacct tctcctcact attaagcagg
     1081 atcacgtcat aaaaacgagg aaggaccttc tttttggtca gataaagcag gaagagagtt
     1141 agtcctatcc aagcgagcag acccaatatg gcttctgtcg aaaaaggctc cactgctatt
     1201 ttgtaaaaga tatgaagagg ataaaggaga aatggaatgt ctctaacttt gtcaacaata
     1261 cttccaaaag tcgactgaag aaagaagata aatattaaag gtatgagaac tcctatccca
     1321 atcatcacat tcgaaaaaat agactgatac tttctgaaga ccgtagtttg agccaagaaa
     1381 tgtactgcca ctaccatcac taaagtaaca gagacaaata ataaggtcaa ggacagtagc
     1441 atcaaaggca aacccaacca cagagaaggt gctagcctaa tgtagaggac cagaaaataa
     1501 gctaggattg gtacaattcc agctagagct ggcaagagga cagacagacc tttggccatt
     1561 ataatctctg attctttaaa ggcatagggc ctataggagg ccaggtcctt actctcataa
     1621 aagacattgt aaaatgcagt gaaagaagtt gaaaaggcca gcaccagtaa aatagcaacc
     1681 atcgagctaa aataaatagg tatttcctca aaaggaaaat gaatggctat attactaaaa
     1741 cagatgagca tcaagagact ggaaaaaatg taagaactta ggactctagc ggaaacattt
     1801 acttttttcc caggattctt agcctgcttc tttcgtagat tagccagatt agcttcttga
     1861 gatgaataga ggatattgat atcaactaat tttttaatga ccttgagacg catctgaaac
     1921 ctcctctttt ctaccagcaa ggctaaggta gatactttcc aaagactggt ctgggttgtc
     1981 ttttctcaag tcctctacct taccacaata aatcaaatgc ccctttttca aaatagcaat
     2041 ccgatcacag acttgctcag ctacctctag cacatgagtt gaaaacaaaa ctgtcttacc
     2101 tttttgcgca tgctccttca tcatttgctt caaatcaaag gcggcctggg gatccaaacc
     2161 agtcaagggt tcgtccaaaa cccaaatatc aggatcagac aagagtgccc cgatgacaaa
     2221 gactttctga cgcattccat gagaaagagt ttcaataacc tgatagcgat tttcagcaaa
     2281 atcaaaaacg ttcaatagcc tagctagact agcctccaag tcagatctac tcagatcata
     2341 ggatgaggcg atcaattccc aaaattcatt ggccgttaag cgtaaaaata agtcaggcga
     2401 gtctgctacg tagccaatct ttcgtttaat agccaagcga ttttccgata actcctgacc
     2461 gtctaccaaa atacgaccac tgctgggtga aatgatactg actagggatt ttatagtggt
     2521 cgattttcca gccccattat gaccaatcaa gcccataatc tctccatttt caatctgcaa
     2581 attgagatta ctcaaggcct ttttatcacc atacaactta ctaacatttt gaaattcaat
     2641 catgggacaa ctcctatctt tatctgtatt atatatcgct atactagcac tttgatacaa
     2701 aaaaatcaat actttatttt aagtagttaa aatagtttcc ttctatctta cgcaaacgtt
     2761 tgcgctaata gatactttat gatagaataa agaacaagat tgacaagtaa gaggaaacat
     2821 tatgcaaaat caaacactca tgcaatactt tgaatggtat ctgccccacg acggtcaaca
     2881 ctggacgcgt ctggctgaaa atgctccaca cctagctcat ctggggatca gtcacgtctg
     2941 gatgccacca gccttcaagg caaccaacga aaaagatgtc ggctatgggg tctatgactt
     3001 atttgactta ggagagttca accaaaaagg gactgtccgc accaagtatg gtttcaaaga
     3061 agactatctt caagccattc aagcccttaa agcgcaggga attcaaccta tggccgatgt
     3121 ggttctcaac cacaaggctg ctgctgatca cagggaagcc tttcaagtta ttgaagtgga
     3181 tcctgtagac cgtacagttg aacttggaga acccttcacc atcaatggct ggactagttt
     3241 taccttcgat ggtcgccaag atacctacaa tgacttccac tggcactggt accacttcac
     3301 aggtacagac tatgatgcca aacgccgtaa gtctgggatt tatctgatcc aaggggacaa
     3361 caagggctgg gctaacgagg aattggtcga taacgaaaac ggaaactacg actacctcat
     3421 gtatgccgac ctagacttta aacatcctga agtcatccaa aacatctatg actgggctga
     3481 ttggttcatg gaaacgactg gtgtagctgg tttccgtttg gatgccgtta agcatattga
     3541 ctctttcttt atgcgcaact tcatccgcga tatgaaggaa aaatacggtg acgatttcta
     3601 tgtttttggt gaattttgga acccagacaa ggaagccaat ctggactatc tcgaaaaaac
     3661 ggaagaacac tttgaccttg tcgatgttcg tctccatcag aatctctttg aagccagtca
     3721 agctggcgca aactatgacc ttcgtggcat tttcacagat agcctggttg aactcaagcc
     3781 tgacaaggct gtgacttttg tcgacaacca cgatacccaa cgaggacaag cccttgagtc
     3841 taccgttgaa gaatggttca agccagcagc ctatgccctc attttgttac gccaagacgg
     3901 ccttccatgt gtcttttacg gagactacta tgggatttca ggccagtatg ctcaagaaga
     3961 tttcaaagaa atccttgacc gcctcctagc catccgaaaa gatttggcct atggagaaca
     4021 aaatgactac tttgaccatg ctaactgtat cggttgggta cattcaggtg ctgaaaatca
     4081 atccccaatc gcagtcctta tctcaaatga ccaagaaaac agcaagtcaa tgtttgtcgg
     4141 tcaagaatgg actaatcaaa cctttgtaga tttacttggt aaccaccaag gtcaagttac
     4201 aattgatgag gaaggttatg gacaattccc tgtctcagct agatccgtaa gtgtctgggc
     4261 agtcaatacc atctaatagc tcataataac caagctaggt ccaagcggat ttggcttttt
     4321 tgtattcaca aaaagaccta cccaaatgga tagatcttta cttgattaca atttacctgc
     4381 tactgcatcc aacaattctt ggatcttagg ttggttgctt cctcctgcca tggccatgtc
     4441 tggtttacca ccaccacgtc catcgatgat tggtgctaat tctttgacaa ggtttcctgc
     4501 atgaaggtct tttgtcttgc ttgctacaag gacattgact ttgtcaccga tagcggcaac
     4561 taggacaaga agatcagagt agtctttttg tttccagtta tctgcaaagg tacgaagggc
     4621 acctgcatcg gatacagaca cttgactagc aatgtaacga tgaccgttga cttccttaac
     4681 atctttgaag atatcgcctg cggctgcagc tgcggctttt tctttcaact cagcattttc
     4741 tttttgaagt tgacgaagtt gttcttgaag tccttctacc ttgtgaggta cttccttgac
     4801 ttgaggtgct ttcaaggttg ctgcgacagc tttaagagca tcctcttgtt cacgataggc
     4861 ttcaaaggct tccttaccag tcactgccaa gatacggcga gttcctgaac cgattccttc
     4921 ttctttgaca attttgaaga gaccaatctc agaagtgttg ccaacatgag taccaccaca
     4981 aagttcaata gagtagtcac caatagtcac gacacgaact tccttgccgt atttctcacc
     5041 aaagagggcc atcgctccca tttctttagc agtgtcaata tccgtttcaa ctgtcttaac
     5101 ttcaagagct tcccagattt tttcgttgac ttgctgttca atcgcacgca attcttcagc
     5161 agttacagct tggaagtggg taaagtcaaa gcgaaggaat tcaacttcgt taagagatcc
     5221 tgcctgtgtt gcgtggtttc caaggatatt gtgaagggca gcgtgaagca aatgagtcgc
     5281 agtgtggttt ttcatgacac ggtgacggcg attgctatca attgccaagg tatattcttg
     5341 gttcaaggca agcggtgcaa ggacttcaac tgtatgaagg gcttgaccat ttggggcttt
     5401 ctgaacattg gtcacagtag ccacaacctt acctgactca tccaagattt gtccgtggtc
     5461 agcgacctgt ccacccattt cagcatagaa tggcgtttcc gcaaagataa gtgaggtagt
     5521 tccttctgat acagcttcta cttctgcatt gtcagcaacg atagccacca atttagaaga
     5581 caattggcta gcattgtggt tgaagacact ttctacagtg atgttttgaa gagtttcatt
     5641 ttgcataccc attgagccac ccttgacagc tgacgcacgc gcgcgttctt gttgttcttt
     5701 catggctgct tcaaaacctt cacggtctac agtcatacca gcctcttcag caatttcttc
     5761 agtcaattca actgggaatc cgtatgtatc atagagttta aagacatctt gaccagcaat
     5821 gacagattga cctttttctt tcaagtctgc cacaatgcct tgggcaaagt gttgacctga
     5881 gtgaagggta cgggcaaatg attcttcttc gctcttaacg attttctcaa taaagtcacg
     5941 tttctcaagc acttctgggt agtagctttc catgattttt ccaacagttg gaacgagttt
     6001 gtaaaggaaa ggctcgttga tacccaattt ttgaccatgc atagaagcac gacggagaag
     6061 acgacgaaga acataaccac gaccttcatt tcctggaagg gcaccatcac cgatagcaaa
     6121 tgaaagagaa cgaatgtggt ctgcgataac cttgaagctc atgttgtcgc catcttggtc
     6181 ataaacctta ccagacaatt tctcgacttc acggataatc ggcatgaaga ggtccgtttc
     6241 aaagttggtc ttagcccctt ggataacggc caccaaacgc tccaaaccag cgcccgtatc
     6301 aatgttctta tgtggtaatt ccttgtattc gctacgagga acagcagggt ctgcgttaaa
     6361 ttgtgacaaa acgatgttcc agatttcgat gtaacggtcg ttttcaatat cttctgcaag
     6421 caggcgaaga ccgatatttt ctgggtcaaa ggcttcccca cggtcaaaga aaatctctgt
     6481 atctggtcca gaaggtcccg caccaatttc ccagaagttg tcctcaattg gaatcaagtg
     6541 acttggatcc actcccactt caatccagcg gttgtaagaa tctttatcat ctggatagta
     6601 agtcatgtaa agtttctcag ctgggaagtc aaaccattca gggcttgtca aaagctcata
     6661 agcccaagtg atggcttcat cacggaagta atccccgata gagaagttcc ccaacatttc
     6721 aaacatggta tggtgacgcg cagtcttccc tacgttttcg atgtcgttgg tacggatagc
     6781 cttttgggca ttggtaatac gtggattttc agggataatg gtcccgtcaa agtatttctt
     6841 gagggttgct accccagagt tgatccacaa aagagttggg tcatttacag gaaccaaact
     6901 tactgatggt tctactgagt gacctttggt cgcccagaaa tcaagccaca tttggcgtac
     6961 ttgtgcacta gatagttgtt tcatattgtc tccttattta cttgtttaat gtgattggct
     7021 ttccagcatt tccacatagt caatcgcgac acagagggaa atgactaggt ctgcataagc
     7081 gtcttcaaga accgttacgg tataggtaga ggtcagatgg aagagttcct tcttaatttc
     7141 cgcaatcaac tgatcgcgat catccagcaa tttgaaattc aaatcccaga tattgccctc
     7201 gatacgaaga cctagattat caaactcata cttatctcgc cagaaggtca acttcttacg
     7261 aatgacaaaa ctcgagccat cccgaagctg aatctcaaaa cgaggaagca aggtcaagat
     7321 ttctttacta atctcactga cttgttcacc agccgcatca tagatggtaa aggttttagg
     7381 aatcttaaaa aatgatccct ccacctgata ggcaatttct cccctgtcat ccttgatagc
     7441 gaagcgttcg cctccaagac gaaacttttg tttgacaaga aatgttttca tcaacacctc
     7501 caaaaatcaa aagacaagct catatcacga agggcgaaaa accgcggtac caccttcatt
     7561 caatgaactt gtcattctct tgttcttatg caattgtatg attgagtagc atgacttcct
     7621 agcttagatg gctcgcagca ccgccatttc tctggactaa gacaagtgaa aatcaattct
     7681 caactttctt attataacgt ttttttaagc ttgcgtcaac tggaaatgat ctccgttgaa
     7741 ttagaccaat tccctacatc tctgattact ttttcaggat atattttttc ttactgccgt
     7801 ttttcttttt atcccaaatt ttcatattac taaacacagc tactagaata tttccaaata
     7861 taaaggtgcc tatcacccaa tatatggact cagttgttag gtattgtcga tccaagccat
     7921 cctttaaatg ggatagtata acagtttggt taacaatcat aaaggttggc cagaaacttt
     7981 ttttgaaaaa agtagacatt ttcattattt gttgccgctt tctgtaaggt taatactcaa
     8041 taaaaatcaa aaagcaaact aggaagctag cctcaagctg tacttgagta cggcaaggca
     8101 acgctgacgt ggtttgaaga atataggctt agtatactac taggcaagca aataagcaac
     8161 tagaatagaa aaagataggg ttctaaaaac tgacttctat tccttaaaaa cgaaccagct
     8221 tgactgattc gtcttcttac gtttatctcc tacttccgat acattttaaa ctgtaggaag
     8281 aggtcgctat atttccctgt ccatttatgg tcaaatttct cataaacttc taggtgtttc
     8341 atggtttcaa catctggata gaaggcctta tcttcctttg tttcctctgg gagcaattcc
     8401 ttcgctggta ggtttggtgt tgaatagccg acatactccg cattttggag agcgttttca
     8461 ggtttcaaca taaagttgat aaaggcatag gctgagtctt ggtttttaac tgttttggga
     8521 atgaccatat tgtcaaacca aagattgctg gcctctgtcg gtaccacata acgtagattt
     8581 tcattttttt ctaacatttg gctggcttca ccagagaagg tcacgccgat tgcaacatta
     8641 ttctgaatca tgtagccctt catctcgtcc gcaacgatag ccttgatatt tggagtcagt
     8701 ttgtagagct tatccactgt ctcttccaac tgctgcggat ccttggagtt gaggctgtag
     8761 ccgagggaat tgagtcctag tcccagcacc tcacgcgccc catcaaaaag catgatagaa
     8821 ttcttatact ccggcttcca aaggtcatcc caatgctcag gcgcttcatc taccatggtt
     8881 tcgttgtaga caattcctaa ggttccccag aagtaaggga tggagaattt attacctggg
     8941 tcaaaggact ggttgagaaa ctctggtccg atattttcga ttccttcaat ttttgaataa
     9001 tcaagcggaa ccaagaggtc ttcgtccttc atcttgttaa tcatgtattc acttggaatg
     9061 gcaatatcgt aggtcgttcc accctgcttt atcttagtgt acatggcttc gttggagtca
     9121 aaagtctcgt actgaacttg aattcctgtt tcttctgtaa actgagtcaa gagttcagga
     9181 tcgatatagt ctccccagtt atagataacc aatttttgac tatctcgact attgatttta
     9241 ctatctaaat gagtcgcaat tccccacaag acaaggataa tcgctgcaat tcctgctaaa
     9301 aatgaataga tttttttcat gcttgctcct ccttctcacg agagataaag taataaccta
     9361 caactaggat aatactaaag agaaagacta gagcagacag ggcattgatt tctaaggaaa
     9421 tccccttgcg agcacgagag taaatctcga ctgatagggt tgaaaagcca tttcctgtta
     9481 caaagaaggt cacggcaaag tcatctaacg aataggtgaa ggccatgaaa taaccagtaa
     9541 tgatagacgg agtcaggtaa ggaagcatga tttccttgaa catctgaaat tgactagctc
     9601 ccaagtcata ggccgcatga atcatgtcgc cattcatttc cttgagtcga ggcaagacca
     9661 tcaagaccac gataggaatg gagaaggcca cgtgactaga tagaacggtc aaaaagccaa
     9721 gtgaaaactt gagttgggta aagagaatca agaagctagc accaatcata acgtcaggcg
     9781 caaccatgag gatattattg agtgatagaa aggcttcttg gtatttctta cgagactggt
     9841 agatgtaaat ggcaccaaaa gtcccgataa tggtcgctat caaggctgat aggaaggcca
     9901 agaaaaatgt ctgagccaaa atcagcatga gtctcccatc tccaaacatg gtttcaaagt
     9961 gagtccagct aaaacctgta aagctattca tatcatcacc agcattaaag gcatagccaa
    10021 tcaagtaaaa gataggcagg tagaggacca gaaagaccag tcccagataa aggttggcaa
    10081 attttttcat cgttctctcc tttccttagt cacccacatg gtgatgaaca tggtcaggat
    10141 gagaatcaca ccgatagttg aacccatacc atagttgtca ttggttagaa aattctgctc
    10201 aatagccgtc cccaaggtga taacgcggtt cccaccaatc aaacgggtca gcatgaagag
    10261 actcaaactt gggataaaga ccgactgaac cccacttcgc acaccgttca tagatagagg
    10321 gaagatgaca tgacggaagg tctcccactt agttgcacca aggtcgtaac tagcattgat
    10381 gagattatta tccatatcgt ctaagacatt gaaaatcggc aaaatcataa aggggagctc
    10441 gatgtagctt gcgacaaaga taaatgagaa atcagtaaat agcaactgct gtgaaccaat
    10501 tccgataaat tccaagaatt ggttaataga gccattctga ccaaaaatcc cgataaaggc
    10561 ataagcctta agaagaaggt tgatccaagt tggcagaata atcagcataa tccagagttg
    10621 acggtgtttg agacgggtca aaaagagggc cgtcggataa ctgataagca gtgtcacaaa
    10681 ggtcacaatg cctgcataaa gcactgagtt gaaactcatt ttaagatagg tcaagttttg
    10741 tgacgcaaag taagatttgt aattttctaa actgaactgg ccttcgatgt tgaaaaagga
    10801 ttgaccgaaa atcaagacca agggtgccaa tacaaagagg gcaatccaaa gcatgtaggg
    10861 tactacaaag agtttagagc ttgttttctt catctctttc ctcctcgatt gcattgatca
    10921 aacctgcttc ttgctcttcg atttctacgt actcctcaat acgagcatcg aactcttctt
    10981 cggtttcatt gagacgcatg atgtggatgt cttctggttc aaagtccaga ccgatttcct
    11041 cacccacgat ggccttacgg gttgagtgga tcatccattc atttccaagt tcgtcatagg
    11101 cgataatttc ataatgcacc ccacggaaga gctgggtatc gaccttaact tgaagcttgc
    11161 cttcttcagg aagggtaatg cgcaagtcct ctggacgaat aacgacctca acaggttcat
    11221 ttggcttcat cccaccatca accgcttcaa agcgtttgcc gttaaattcg accaagtagt
    11281 cctcaatcat ggtacctggc aagatgtttg actccccgat aaaggtggca acaaagtggt
    11341 tgattggctc atcgtagatg tccacagggg ttccagactg gacaatctcg ccatcattca
    11401 taacgaaaat ccagtcactc atggcaagag cttcttcctg atcgtgagtg acaaagacaa
    11461 aggtaatgcc caatcgttgt tgcagttcac gcagttcgta ctgcatgtct gttcttaatt
    11521 tcaagtccag cgctgacaag ggctcatcca acaaaaccac acggggttgg ttgatgatag
    11581 cacgggcgat agccacacgc tgacgttgtc ctccagaaag tttgcggatg gaacgttttt
    11641 cataaccttc caactgaacc atcttgagaa cttccgctac acgttgctcg atttctttct
    11701 tatcaatgtt acgcaagcga agtggaaagg caacattttc aaacacattc atatgtggga
    11761 acaaggcata ggattggaag acagtatgta cgtcgcgctt gttggttgga atatcattga
    11821 tacgaacacc gtctagcatg atatctcctg tcgtcgcatc cagtaaacct gcaataatgt
    11881 ttaggatagt tgatttcccc gaaccagatg cacctagaag ggtgtagaat ttcccttctt
    11941 ccaactcaaa gttgatgtct ttgagaacct tggtgttgct gtcttcaaaa actttagaga
    12001 cgtttttgaa ttcgataatt gattttttca attggcataa attccttctt tttcatagat
    12061 taaccgatcg gggctctgtc aggtcgccac tacctcttgc agggagtaaa accacctgca
    12121 tacatcttcg ctaccaatag gctttcaccc ccctttccat gacatagcag cagcttttca
    12181 aatacagctt cctacttgct ttcacccaag atccggactt ctctttcaag cgtaatacct
    12241 gagtgttcct tgactttttc gataaccgat tggatcaagt cctcgtagtc tttggccgtt
    12301 ccatctgcga cattgatcat aaatcctgca tgcttttctg acacttctac gccaccgata
    12361 cgatagcctt tcaagccagc ttctgaaatt aactgacctg caaaatgccc gactggacgc
    12421 ttaaagaccg agccacaaga tgggtattcc aaaggttgct tgagttcacg taggtgcgtc
    12481 aagcggtcca tttcctgctt gataacctga tgggttcctg gggctagggc aaatttaact
    12541 gacaagacaa ctgcaccaga ctcctgaata gctgaatggc ggtaaccaaa agccaagtct
    12601 ttagcagaca gggtttcgat ttctccatcc ttggtcaaga ccttacaaga ctgcaagatg
    12661 tgagcaatct cgccaccata ggcacccgca ttcataaaga cagcaccgcc aacgcttcct
    12721 ggaataccac aagcaaactc aaagccagtc aaactatgac ggagggcaat gcgagttgtt
    12781 tcaatcaagt tagccccagc ttctgcttca atggtatagc catcaacaga aacgttattg
    12841 agcttgtcac acaagatgac aaatccacga atcccaccat cacgaacgat gatattgctt
    12901 gcattgccaa gaaccatcca agggatattt tcttggttgg caaatttcac aacgcgagcc
    12961 aactcaaaac gatttcgtgg aaagaccaaa taatcagcct ctccacctac ttttgtataa
    13021 ctatagctat gcaagggttc cttaaaacgg atatcaattc cttctaagat ttcaagcatt
    13081 ttttctctta cagacatgtc actcttcctt ttacaaaatt cattccatta taccattttt
    13141 agagacattt gacgaccata aaaatacctt gtttggattt tgcataagaa aaagaggttc
    13201 cccccttttt atgatttttt acaaaagatt tccttggttc cataggcaac cagaacgagc
    13261 tccagtgcta gaatcacttc aaccaagact ggatttgtca accagcctac ttggaaaaga
    13321 gatggtgcca gatcaaagaa ggcatgcaag ccataggctg ctaggagata aatccatttc
    13381 ttctggcgaa cagcttggta aacccaaact gtcaaaagta attggaaacc aagcgccaag
    13441 attcgctcaa aaccaagcaa ataaatctgc cagaccgaaa gtgactgaat ggtttttaac
    13501 atattttcag acagtaattg cataacctgt ggattctgag tttgaactgc cgaaagaacg
    13561 atgtaaagat tgagtaaact aataaggcct agaaaaatca actccaagcc accatgccct
    13621 aggccatagg ccaaggcatc tgccttttcc aaacttctct ttttctccaa ccatttgaag
    13681 aaaacaagac gagccgtttc ctcaaaaaat gctgccatgg ctaggccata gataatatag
    13741 ataagcggat gatcttgcaa gagggcaata ctaccgtctt tttgaggatg caaaatcaag
    13801 atatgcacca gtttttccaa aatctgcgaa gagacaaaga aagcgactgc acccaagccc
    13861 aagacagcta gattaatctg gtatttcttt ttggcaaacc aaatgcttcc tatcagaaaa
    13921 gctagcaaca gcaacatggt aataatgata tgaatggtca ttttcttctc ctattctgcc
    13981 ttttcaatat cttttttcat ctcgtcaaca ttgaacttag caaacaagta ttgacggtct
    14041 tggactggga aacgttggtc caactggtca actgctccca cctcgataat gccttccttg
    14101 atgacaaaat ccatgacatg tccaccgaag gtcaaatcat ctgatatgaa gtgcagatgg
    14161 tagcctgcca cactgacccc atggaaaatc tcaggcgtcc agaaaccaac aatagtcccc
    14221 gcaacattgt cacgactata ttccggttga tgggttgcga catcagcaaa cttggtatcg
    14281 ggtgttgact taggaatcat acgcacatgc atatgtgaaa attccccccg aatcttgata
    14341 gagcggaaaa gattttcccc atcataataa gactcaattc gttctttcaa ttccttgtct
    14401 gtcatctcaa agcgctggcg gaaaatgacc tctgcctgat gcggtaccac tgcagcgtaa
    14461 ggaataaggg catctggtga cacttcccca atttctggct ggtctcctga ccctttggcc
    14521 tgataagcct tgccatccaa gacaatcaat tccccatcaa tggaatccaa ggttcccaaa
    14581 ccaaggtcac catgttctag caattctcct actgtcatag taccaccata aaggccagcc
    14641 atcaaggctc caagggtatt gtattgaaat aatttcactg gttcctgcac gttcttatcc
    14701 attcactttc ttgtctgtta ttctataaat cttactccta agtataccac atttgcccct
    14761 agatgtgaac gagagaaacg ctctagacat tgccaagaag gaaaaaaaaa ggtacaatgt
    14821 aacaaaatca agggaggtct ggaatgaaga aacaaagcaa gtacaaagag gtcgtttcct
    14881 atctgaaaaa tggtatcgag tctggacgat ttccgacggg tagtcgcctg ccttctatcc
    14941 gtcaactgag ccttgacttt cactgcagca aggacaccat tcaacgagcc ctgctggaat
    15001 tacggcacga acaatacctc tatgccaagc ctcagagtgg ctactatgta ttagaacaag
    15061 ggcaacatca agacctagaa atcgaggtta ccgacgaaca tgccagtgcc tatgacgatt
    15121 tccgactctg tgtcaatgaa accttgattg gccgagaaaa ctacctcttc aactactatg
    15181 acaatcaaga aggattagaa gacctaagac agtccattca caaactcctc tttgagcaag
    15241 ctctctactg caaggctaac caactagtac tgacttctgg aacccaacaa gccttattta
    15301 tcctctctca aatatccttt cctagacaag ccaaggaaat cttggtggaa cagccaacct
    15361 accatcggat gaatcgcctc ttgattgcac aggggctgga ctatcaaacg attgaacgag
    15421 gcattgatgg gattgacttg gaggagctgg aaggccactt caaaacagga aaaattaaat
    15481 ttttctacac cattcctaga tttcactatc ctctgggaca ttcctattct gagcaagaca
    15541 aacgatctat tcttaactta gctgccaagt atgatgtcta tatcgtagag gacgattatc
    15601 tgggtgattt ggactccaag aagggccaaa ccttccacta tcttgataca gaggagcatg
    15661 tcatttatat caagtccttc tcgaccagcc tttttcctgc ccttcgtatt acagcactca
    15721 ttcttccaaa tgctatcaaa gaagcatttg tggcctacaa aaatatccta gactacgaca
    15781 gcaacctcat tatgcaaaag gccctgtcac tctatattga cagtcaattg tttgaaaaaa
    15841 atcgtttggc tcgcttgacc aatcatgaat cttaccaaaa acaaatcgag gaaaggataa
    15901 ctaaaacacc ttgtcccctt cctcattatc ccctacacga tggtttattg ctagacctga
    15961 gacagtatcc taaaatcgcc agtctcaaac acagtcaacc gggcttggac ttctttgaag
    16021 aggcctattt aagtacctgt ccttatcaat ttgccaaggt gtccctagac aatctggaaa
    16081 atgttttaaa ctatttaaaa gcagaattgg aatgacatcc aactctgctt tttcttattc
    16141 ttcaacttca gttagacttg ctgctttttc aagatagctt tggtaaattc cttcatcctt
    16201 aagtttttgg atgaccttgt ctaccacttc tttcaaatca tcactatttt ttctaagagc
    16261 aacggcattg gcgtcgccgt ccttcatctt caagctgaca gttgcgacag ctaagccagc
    16321 gtttttagca gcataactaa gtgcaacagg ctcatccata tgaacagcat ctacttttcc
    16381 agcctgcaat tcattgactg cttcacccat attagttagg gaagttaatt gagcttttgg
    16441 caattgttcc ttgaccattg attctggaac agtccctttt tgggctgcaa tattagcact
    16501 ttctaggcta gttaaatcct tgtatttttc cacatcagcc ttacgaacca agaaactaat
    16561 cttgttttca tagtatggga ttgaaaaatc aaagacttct tttctctcgt cagtagcact
    16621 aattcctgca actgctaggt cagccttacc agtttgaaga ctggtcaaaa cattgtcaaa
    16681 actcatgctt gagatttcca acttaacccc aagttcatca gcgatagcct gagccatgtc
    16741 gatgtctgca ccgactacct ggttctttcc atcaaccaat gattgaaatt caaagggtgc
    16801 atagtcagga ctggttgcca caactaattt ccccttttgc ttaatggcct caacagctga
    16861 ctgagaacca ttagaacctg actggcaagc tactaagaag aaacttgcaa gaaaattaca
    16921 taaaacaaat atccattttt ttgatttcat aaataaacaa cctctctgtt aattttgtat
    16981 aattataacg atatccaagt tacttgtcaa gtgtttttta aatttttatc tcaaaaatat
    17041 tttttcgttc aaaaaaagga gccatcagtt gatttcaagc tcctttttat acagaattaa
    17101 actattttat agttcgacaa tcttacctgt ttcaaagtag acaacccatt cacagatatt
    17161 tttagcatag tcaccgatac gctccaagta ggaaataact tggaaataat cacgacccgt
    17221 aacaatggct tctggatttt tcttaatctc ttcagtcgca aggtcacgga tagtttcaaa
    17281 atagtggtta atttgctcat ccatggaggc cacccggtat gcgtcgtcaa cagaaccatt
    17341 aagataaaga tcaagtgctg cttccacaac gcttttaact tcacgtccca tttttttaat
    17401 ttcttcctct acagctggga tgcgttcttc ccccttcata cggatggttg cctgggcaat
    17461 ggctacagcg tgatccccca tacgctccac atctgataca gccttaagga cagtcaagac
    17521 tgtacgcaaa tcttgagaga ctggttgttg gagtgcgatc atttcaaatg atttcttttc
    17581 cagtttcact tcgtattcat ttacttctgc atcatcttcg atgacctctt ttgccaggtc
    17641 acggtcatgc gtgacaaaag cacgtaccgt acgattgatt tgtgagagca cttcttgtcc
    17701 catagcgtag aactggttat gtaatttctc taaatcttct tcaaattgag atcgtaacat
    17761 ctttcatctc cttatccaaa ttttcctgta atatagtctt ccgtttcctt gtgttgggga
    17821 tcaaggaaca tctgcttggt atcattaaat tcaatcaaat ctccatctag gaaaaatcct
    17881 gtcttatcag agatacgtga agcttgctgc atggaacggg ttaccagaag catggtgtac
    17941 ttgtctttta gaccatacaa ggtttcctca attttaccag ctgaaatcgg atccaaagcc
    18001 gaagttggct catccaagag gatgatttta ggactagttg ccaagacacg ggccacgcag
    18061 acacgctgct gttgaccacc tgacaatcca atagctgaat catatagacg atccttgacc
    18121 tcatcccaga tagaggcacc ttgcaaggct ttttctacgg cttcatccag aacctgctta
    18181 tccttaattc cattgatacg aagcccgtag acaacattct catagatagt catagggaaa
    18241 ggattaggtt gttggaaaac cattccgatt tccttacgta attcaaccgt atctgtacgc
    18301 ggactgtaga tgttgtgacc attgtacacc acggatccag ttgtggtcac ctctggattg
    18361 agatctccca tgcggttgag agacttgagg agggttgact tccctgatcc agatggacca
    18421 atcaaggctg taatttcctt aggttggaaa gatagggaaa cactattcaa agccttcttt
    18481 ttattataat aaacggacag gtctgatacc tgtaaaatcg catctgtcat acggtttcct
    18541 ttctaaccaa agtgaccaga tacatagtca ttggtggact gtagcttggc attttggaaa
    18601 atagttgcag tcttgtcata ctcaatcaaa tcacccaagt aaaagaagcc tgtatagtca
    18661 cttgcacgag cagcctgctg catattatgc gttacaatga tgatggtaaa gtttttcttg
    18721 agctcaaaca tggtctcttc tagttgcatg gtcgcaatcg gatccaaggc tgaggctggc
    18781 tcatccatta agaggatatc tggcttaaca gagatggcac gagcgataca gagacgttgt
    18841 tgctgaccac ctgataaggt caaggctgac ttgtggagat cgtctttaac ctgatcccag
    18901 agggcagcct gacgaaggga ggtttctacg atttcatcta ggacttgctt atccttaact
    18961 ccagcacgtt catgcgcaaa ggtaatatta cggtaaattg acttagcaaa tggattgggg
    19021 cgttgaaaaa ccattccaat gtgtttacgc atttcataaa cgttgatttc tggacggttg
    19081 acatcaattc cacgatagag aatctgccca gttactttag caatatcaat ggtatcattc
    19141 atgcgattga gactgcgtaa gtaggtagat ttccccgatc ccgacggacc aatcaaagct
    19201 gtaattttat ttctttcaaa ttgcatatca atccccttaa tggattcatt tttaccatag
    19261 taaacatgga catccttagt agaaagggct actttttctt caggaaaggt aaggatatgc
    19321 ttctcatccc agttatatgt tgacatggct tctcctttag gcagcggtta atttcttgtg
    19381 tagatagctt ccgaacttac gagctccaaa gttaaaaatc aggataaaga tcaggagcac
    19441 agcggcagaa cctgctgata caatggttcc atctggaata gtgccttcac tattgacttt
    19501 ccagatatgg acagccaagg tttctgcttg acggaagata gagatggggc tagtcacact
    19561 gaggatattc cagttagacc agtcaagagc tggcgccgat tgccctgctg tatagatcag
    19621 agctgcagct tcgccaaaga tacgaccaga tgccaagacg acacccgtta caatacctgg
    19681 aagcgcttct ggaataacaa catgaaccac tgtctcccag cgagaaatcc caagagccag
    19741 accagcctca cgttgggtat ggtgaacgtg tttcaaacta tcctctacat tacgcgtcat
    19801 ctgaggcaag ttaaagactg tcaaggccaa ggcacctgaa atgattgaaa atccatactc
    19861 aaactgaact acaaagatca agtaaccaaa gagacccacc accactgatg gtaaagagga
    19921 caagatttca atacaagtcc gcacaaagtt ggtaacagga ccttttttag catattcagc
    19981 caagtaaatc ccagctccca tagaaagagg tacagaaata atcaaggtaa tgaccaatag
    20041 gaaaaaggaa ttgtaaagct gaatgccaat cccaccacct gcttgaaaag cagaagacct
    20101 tccagtcaag aaagaccaag agatatgggg caagccccga accaagatat agagaatcaa
    20161 ggaagccaag attgtcacaa tgatgctagc aatcgtatag aggacagctg ttgcaagttt
    20221 atctaatttc ttagcgcgca taatttttct ttcctctttc tttcgtaatc aatttaatca
    20281 cactgttaaa aactaaactc atcaagagca gtaccaaggc cagtgaccag agaacattat
    20341 tatttacagt tcccatgaca gtgttcccaa ttcccatagt taatatagaa gttaaagttg
    20401 cagctggtgt ggtcaaggaa gttgggataa cagctgagtt tccgacaacc atctggatag
    20461 ctaaagcctc accaaaggca cgcgccatcc caaagaccac tgcagtgaaa ataccagaac
    20521 gggccgcctt caagatcaca cgccagatag tctgccagcg agtggctccc atagcgaaac
    20581 tggcttcacg ataataacga ggaaccgcac gcaagctatc cgttgtcata aaggttacgg
    20641 tcggcaaaat catgacaaag aggacggaaa tccctgacaa aatcccaaaa ccagtcccac
    20701 caaagacact gcgaacaaag ggaacgacga cttgcaagcc aataaatccg tacactactg
    20761 aaggaatccc aaccaggagt tcaatagctg gttgcaaaat cttcgcccct tttggtgata
    20821 cttcggtcat aaaaactgct gcaccaatag caaagggggt tgcgataagg gctgagagaa
    20881 tggtaacgat aaaggaaccc aaaatcatag gaagggcacc aaattcttta ctagaaggat
    20941 tccaaattcc tcccaaaaga aagtcaaaga tattcacacc attgacaaag aaggtcgaca
    21001 agcctttttg cgctacgaaa accaaaatca tggccacaag gatgactatc aaagaaagac
    21061 aggcaaaggt caaacctttt cctaatttct ccagacgaga attctttgat ggaagcaaca
    21121 ttttcttagc taattcttct tgattcatta ttgtctccct tccaacactg tcacagttcc
    21181 ggcagcatct ttttcaacct tcatttcctt aatcggaata tacttcaatc ctttgacaat
    21241 cccttcttgg gtctcatccg agagaacaaa attgagaaat tctgcagcca actcattggg
    21301 ctgccccaat gtatacatat gctcataaga ccacaagggc caattattgc tacttatatt
    21361 ttctggactt aagtcatagc cattcaactt catgcttttg accgaatcat ctatataggt
    21421 aagagataaa taagagatag ctcctggact ttttgatacg attgatttta ccgctccatt
    21481 tgaatcctgc tcctgacttt gcatggcaga ctgaccttcc ataatgacag tatcaaaggt
    21541 agcacgagaa ccagagccgg ctgcccgatt gataacagag atgggtaagt ccttaccacc
    21601 aacctctttc caattggtta cctcacctat gaagatttga cgaagttgct ctgtcgttag
    21661 gttatcaaca tcaacctcct tattgacaat cagagccaag ccagctaccg cgaccttgtg
    21721 gtcaacaaga gcagaagcat caattccgtc tttttcctca gcaaatacat ctgagtttcc
    21781 tatatcaact gccccagact gaacctggga caagcctgta ccagaacctc ccccttggac
    21841 attgaccgtt tttccaacat ggatcgtgcc aaattcatct gccgctactt caaccaaggg
    21901 ttgcaaggca gttgagccaa cagccgttat ggattctcca cgatcaatcc agctagcaca
    21961 gcctactaaa caagccgtca gccaaaaagc gataagagac agagcaagct tttttctttt
    22021 tttcactgtt tttctcctcg aaaataatta tgaatactgt gaatttttta agtagttctt
    22081 tatgagttga cgcatgaatt cttaccaaat ttctgcgcaa ttgattattt atataatata
    22141 ggctatatta ctctttccta acctcctttt ttcatatgtg gataaaatct cttgtctatc
    22201 ccttccccca ttgtcaccca ttatagtcat ttcgtgtctc tttttcccct ttttaatgca
    22261 agggaaatta ctctccttag atgataatcc aaaagctaga aaggtatctc aaacctctct
    22321 actctcccag actagtttac aactaaaagg aaaagattct attttatgag aaatctagtt
    22381 tacaagcggt aagaacgcta ataactaaac ttcttgtact ctttgaaaat ctcttcaaac
    22441 cagtgttttg agctatctat ggctagcttc ctagtttgct ctttgatttt cattgagtag
    22501 taaaactaca tgtaatggca atcaagatat caagaatcat cctactaaaa aaatccatac
    22561 tttcactata acatagaata agatatttga ctagcatttt catttgaatc tgaggccttt
    22621 tggaaaataa tttttcaaaa catttccagt aacctttgca aagcccaagc cattgccttt
    22681 aaccaaaact tggtaccaac catttggcag actttctgcc agctgaacga tttctccagc
    22741 cgcatacttg acaaacgctt cttggccaat ttcaaccgac tgttcgacct gactcgattt
    22801 caaggctaaa ccaagagcga aactgggctc aaagcgtttc ttcttaaaag tacccagatg
    22861 cagtccattg cgagcaatct tgagcttccc taaatctggc aaaagttctg gcaagagata
    22921 aagctggtct ccaaaagtct gcaagatacc cggtagattg accttcaaat ggttttgggc
    22981 aaattcctgc cacaaggcaa cttgttcacg gctgaggtta ctcttacttg ccttaaattt
    23041 aggagctgga ttgttaccct taaactgtag atgggcaaca aactgaccct ctcccttaaa
    23101 ctgatgaggg tacatccgag ccgtttctgg caggtcaata ccagctacca ttccattgat
    23161 atgctctact ggcaacaagt caaaatcata ctcttccagc aaccaattga caatctcttc
    23221 gttttcctcg ggtgcccagg tacaggtcga ataaaccaga cgaccacctt cagctaacat
    23281 ggtcactgca tcctccagaa tttctctttg caagctagca cattgactcg gataatctaa
    23341 gctccaatag tccatagcat caggttgctt acgaaacatt ccttcaccag agcaaggggc
    23401 atcaagaacg attaagtcaa aatagccttt aaagaccttg accaagcggt cggcagattc
    23461 attggtcacc acgacatttg tcgctccaaa acgctccatg ttttcaacca aaatcttagc
    23521 ccgtttgctt gaaatttcat tggaaacaag tagcccctcc cctgctagat aggctgccag
    23581 ttgagttgat ttgccccccg gtgcagcagc caagtccaag accttcatac caggactggg
    23641 ttgggctact tgagccacca tttgagcagc aggttcttgc gaataaacta aacctgtagc
    23701 atgctcaggc gatttccctg aaaccttccc atagtggccc caaggggttt gagtaatggc
    23761 atcagaaaag gaaagttgct cttcttttaa gggattgacc cgaaaggccg aaaccgcttc
    23821 ctcctcaaaa gaggcaagaa aatttcttgc ctcatctcct agtatttctt tatatttttc
    23881 aacaaatcct tctggaaatt gcatttaagt tcttttcctt tcgtaaatat aggactgaat
    23941 ttcctcctgc atctcaagag gcaccatcat gacaggctgt ctggtttgaa aatcaggagc
    24001 ttcaccaaaa agggtcacaa cccgatagcc cagactttcc cctaaaatac tagctgcggc
    24061 ataatcccat ggttgcagat aagtgagata ggtcaacaaa cgccctgaca aaatcttggc
    24121 aaaactaatg gccgcacttc catagacacg aacaccaaga accgctcggc tcaaatcagc
    24181 cagcccccat tcattggttt ccagcatacc actattccct gcaatgagaa aatctccaag
    24241 tggtttagtt ttaaaaggag ctaggggcct atcatttaga caaactggaa attccccacc
    24301 accgtggtaa caatcccctt tgaccacatc ataaatcaga ccaaactgtc cctgaccatt
    24361 ttcaaaataa gccatcataa cagcaaaatc ttcctgctgg gctacaaaat tattggtacc
    24421 atcaatggga tcaatgaccc aaaccttgcc ctcttgaacc gaggctcgca gacaaccttc
    24481 ttcagcacaa atcttatcct caggataacg ggacaaaatc tcaccaacca agagttcctg
    24541 aacttctttg tccagtctag tcaccaaatc tgttggagag gacttggttt caacacgcaa
    24601 gtcttcctgc atatggtcaa gaatgtactg acctgctttc ttaacaagct ctttagcaaa
    24661 ttcaaattta ctttccaaga gaaatctttc cttccccttt ttctttggca gcctgaactg
    24721 ctcggtaaag tgaatagcca ctaaccgttt caaattctcg tcccaaacgt ttctcttcgc
    24781 tcttgcttgg cacgaccgct ttgaatccct tataggagtc cagtaacttt ttagcctcta
    24841 ctttgccttc ataggcagct tcaacatcat taaaaaaaga aagcactgaa gcaagttctt
    24901 cagtgctcca cgacaaatct agtgggtaac tatactgttt gttcattaac taataccagc
    24961 tctcattctt gcttctttta gttcttgctt acgataacta cgagggagaa aagcacgaat
    25021 ctcatcttca ttaaaaccga tttgcatacg cttggcatca ataataattg gacgacgcaa
    25081 aagactagga tactgctcaa tcaaatgaag caattccgat accgaaatac tctctacatc
    25141 aatattcaat ttttgaaaaa tttttgaacg agttgaaatg atgtcatcag taccattttc
    25201 ggtcaaggaa aggatgtgtt gcaattcttt tcttgttaaa ggactggtca taatattgtg
    25261 ttccacaaag ggaaccttat gtttttctaa ccaggcctta gccttacgac atgatgtaca
    25321 gctcggtgat agaaatagtg taatcatgct tttctcttct tatctatact ttgctacttc
    25381 tattatacaa aaaaataaag cgcttgacta gggattttta gaaaaaaagc ctattttttc
    25441 aagaaaaata ggctttttgc gaacgattga cacaattgga tttggttaat tcactcttaa
    25501 cgatggtttt aaatgatata tatttttata tatgtaaatt aaaaacatct ttcctttcac
    25561 ttcctacgac ttttcagata cagatagcca aagaagtttt catagagggc aaaaaagagg
    25621 aggaaggcat gaagaaagaa ggtctctggc aaaatcataa taacaggatc cttggctgga
    25681 tcaaaaagcc aggtatcatc tcccacaaag agaatttgat ggaaaagagt aaagaattgg
    25741 tcaaaaccaa tcaaaactcc cccaagtcca atcatcacag gtaagactac tagagccagg
    25801 agactttttc gataaagaga caaaaagtcc tttttcacaa tcctattgac aaagacatag
    25861 aaacttggca gtgtcactag agctactagc tgaaccaaat gaaagagatt cttgaccact
    25921 gcgaaatggt gcagaccagc tgctgacgaa cgaaaatcag gcatctgtaa gacctgacta
    25981 aaaggattgg tcagataatt catcaagata tgaaaattgt attgaatggt ttctggtttt
    26041 agatagactc gattcgttaa gtttagccac tgaatctcca taggatagaa aatccaagcc
    26101 agataaatgg tcagaaggat tgagagggag aggagaaaga gcatagagcc ccaaaaggtc
    26161 aatttagttt tcatcaaaat cccactccgc aaggctagaa accacatgtg tcggtgcgat
    26221 tggcaggcca gctacttctt ctgccttagt aaaacctgtc gtcaccaaga gcgttggaat
    26281 gccattgtca atcccagccc ggatatcagt caaataattg tccccaacca tgattaactc
    26341 ttcacgttcc aaacctaagt gctcaaccgc cttgtccata atgatggcat ttggttttcc
    26401 gatataaacc ggcttcactc gtgtcgctac ttcaagcagc gtaatcagtg agccagcacc
    26461 tggcaaaaga ccgcgttccg tcgggatgtt gaggtcagga ttggttccga taaaatgggc
    26521 acccttttga atagcaagag ttgctgtggc aaatttttca tagtcgactt gccaatccag
    26581 accaactacc acgtaggcag ggttttcctt gtcttccaca taaccagccg ccttgatggc
    26641 ttccttgagt cctgcttctc cgacgacata gacggtcttt tcaagcccca aatcattcat
    26701 atagtcgatg gttgccaaag tcgctgtgta gacagtcgat aggggcgtat cgatattaaa
    26761 attctgagcc aacatctcct taacactctc tggagtgcga gttgtattgt tggttacaaa
    26821 gagataggga atgccccgct tttgcaattc atgaacaaaa gtctctccag cagggattcg
    26881 gtctttcccc ttataaatgg ttccgtctaa atcaattaaa tagcctttat atttcatcta
    26941 tttctcccta agcctttttt atttcttgcc aagtaatgat tgcttgggca ttgataaccc
    27001 catcacttgt aatttcatgc ttgctttcca gtccagtccg ttcaacaacc gatgtaatca
    27061 ctccacctgg tcgaacttcc ttgacatact tgaggttgat tttcttggga atatagtggg
    27121 tcaaaaaatc cgctcccatg acctcaaaaa tccagtccaa gtatttactg ttattgacat
    27181 gaccattcat atccaagtcg taaaaacgaa catggtaatc cttgctgatc ggttcttcca
    27241 aggactcata cttcggtcca cggataagtt ttttatcaaa atcagactgg taaggagcca
    27301 caatctcagg ttcaacagca tggacttttc gactgtcgcg gtccatgaga acaaaggtcg
    27361 ccatcatatg gatgagctcc tgccccgctt cattataaat agtaaagcga cggtagcaaa
    27421 aaagtcgatt gtagctcaag gcttccgttt cgatggtaat ttcttccgca aaacgaggca
    27481 aacgaaccac ctcaatatca tattctgcga taatccagac cagattatag tcttccaaaa
    27541 tggccttatc actaactccc agttcaatcg actgcatccc tgaaacttgc agtgacagca
    27601 aaatcacatc tggaagtttg atatgaccgt tcatatcagc catatcaaaa ggaattttca
    27661 ttttcatttg ataagttaag cccatgatcc tactccaaaa taaatcgttc tgctacagta
    27721 tctcccaaaa agagacctct ctttgtcatg cgaacgtggt caccctcaat ctgcatgagg
    27781 ccttgttgaa ccaaatctct gacaatttct ccataaagtc cagcaaaaga ctgtccaaat
    27841 ttttcctcaa atcgcgccat ggaaaccccg gatttcttgc ggagtcccaa gaacatttct
    27901 tcttccattt gctccttttg actcaggtga tcttctgtaa tacaagcatt gccttcctca
    27961 accgcactga gataatgacg aatgggacca tgatttttat aacgtactcc attgacataa
    28021 ccagatgccc ctgcaccaat accatagtat tcagcattgt cccagtacat gagattatga
    28081 cgactttcaa agccgggttt ggagaaatta gaaatctcat aatgctcaaa acccgctcgc
    28141 tccagctctg caatgatgta ctcaaacatc tccgcttcta gttcctcctt aggcagaggc
    28201 aatttcccac gtcgcatccg gttcataaag accgtatggt tttctaaaat caaactatac
    28261 aaactcatgt ggggaatatc cagtccaatg gctttagcca cattttcctt tacttgctcc
    28321 atggtctgac caggcagagc ataaatcaaa tcaatggaga tgttgtcaaa accagccagt
    28381 ttcagacgat cgatattttc ataaatatcc ttctccaaat gactgcgccc aatctttttc
    28441 aacatcttat catcaaaggt ctggacacct agcgaaacac gattgacagc cgaatttttc
    28501 aaaacagcta tcttatccgc atccaaatcg cctggattgg cttcaatggt caactcttcc
    28561 aagacagaca agtccaagtt tttagtcaag ccattcagta acacctccag ttgcggagcc
    28621 gacagggctg tcggtgttcc accaccgata taaagggttg acaacttttc aatatcataa
    28681 gaacgaaact cttccagcag atgctctaaa tagctgtcga ctggctgatt tttgatgaag
    28741 acctttgaaa aatcacaata ataacaaatc tgggtacaaa atgggatgtg cacataggct
    28801 gacgttggtt ttttctgcat agtaattatt ataccacaaa gactagattc cagataaaaa
    28861 tcaccatccc cagatacata gtccgtccgg agatggtgat ggtttattct tctgttatat
    28921 caatcacaat ctcttctgag tcatcaagag cttcggcttt ttcttgccat tgttccttga
    28981 gattatttaa ttgatttttt gatgcttctg tcgcttgaaa agcataggat ttagcttgag
    29041 caagtatact gtccacagtg atttcacctg actcaacctg ttcttttgtt ttcagaacaa
    29101 aatctgtagc ctgctcctta acttctgtca gtttttcaca gacttgctcc ttggcatact
    29161 ccggatcttc tctcaaatca tctagaaaat cttgagcctg actgcaaact tgtttgccct
    29221 tatcacttgt taaaaacaag gcaagagctg cacctgaaac cgttcctaaa aggattgagg
    29281 ataatttacc cataaggatt ctcctttttt attttttgaa aaatttactt gcaagacgaa
    29341 gagctgacag acttgcacca gtcttgagtg tttttgaacc agctgatgaa gctttcttgc
    29401 tcaagacacg cgcatggtca ttgaggtctg aaacagatag agataaatct gcaacagcac
    29461 tgaagagtgg atcaattgta gccaccttga cattgatatc atctgccaag acattgacct
    29521 tagccaacaa ctcattggtg tgatgcaagg tcacatccac atctgaagtc aaggttttaa
    29581 tcgtcttttc tgtttcatcg atgacacgac caagcttttg tacagtaatg atcagataga
    29641 ccaaaaagac aatcaaagct agggcaacaa gaatatatgc aacttctaac atttagtttt
    29701 cctcctctgt aatatagtaa ggggccttct ttcgattttg ataaataacg atcattatac
    29761 cgagaccgat aaggacaact gacagccatt gggacactcg aaggccgaag aacatgagac
    29821 tatctgttcg cataccttcg ataaccatac gaccgaaacc ataccaaatc aagtaaaagg
    29881 ccgtgatatg acctcgtctg agactcttcc atttccgtct aaaaatcaga atcaaggcaa
    29941 agccaagcag attccataga gactcataaa ggaaagtcgg ttgacggtag ctcccctcaa
    30001 tatacatctg gtcacggata aagccaggta gataatccag attatccact gttgcaccat
    30061 aagcttcttg gttaaagaaa ttaccccaac gccccaaact ttgagcaatc ataacgctag
    30121 gcgccgcaat atctagaaaa tcccaagtat tgatgagttt acggtcagca aagatataga
    30181 gcacaagaac cccagttatc aaaccaccgt aaatggccaa accaccattc caaatggcaa
    30241 aaatctctcc taaattctga ctatagtaat caaatcggaa aataacatag tagagacgag
    30301 ctcctaaaat agccaaggga aaggctacta agataaaatc taaaatatcg tctggtatga
    30361 tcttctttct aggtgcttct ttcatagtca aataaaccgc aagaatcaag cctgtcacaa
    30421 tacataaggc ataccaacga atggctaggg gtcctagttg aatagcaatt ggatcaagca
    30481 ttttgcacct catttcgagc gattagactt gtcagtcgtt cgtcgaacaa acgggtcgca
    30541 tcaaagccca tttccttggc acgataattc atggcagctg cctcaatcac aacagagata
    30601 ttacgacctg ttttaactgg aatacgaata cgaggaatgg ctacgccaga aacttcaagt
    30661 tcctctgcat tgtttccaag acgatcaaag gtcttatgcg tatcgtaatt ttccaaatag
    30721 acagcaagct gaacctgtga agaatccttg acagcactcg caccgtagag actcataaca
    30781 tcgataatac caaccccacg aatttcaatc aagtgtttca aaatttcagc tggttcaccc
    30841 cagagagtaa tctcatcctt ggcaaagata tcgacacggt catcggctac caaacggtga
    30901 ccacgtttga caagctcaag acctgtctcg ctcttaccaa ttccactatc tccctgaatc
    30961 aagacgccca tcccataaat atccatcaag acaccgtgca cactggtacg ttctgccaaa
    31021 cgagaatcca gatagctaga taactctcca gataaacgac tggtagctgc acggctggtt
    31081 aaaatagcaa tcttacattc tctagcagcc tttaacatct cctctggaac caccaaacca
    31141 cgggcaacaa tgactgctgg tgtctcaggt agaaacattt ttttcaaaac ttcataacgg
    31201 ctgttggaag gcatgctgat cagataagac cactccttca tccccaaaag ttgaatccgc
    31261 tctggtgtat agtagtcaaa atagcctgtc atttcaagac caggtcgcgt aatatccgct
    31321 gtattgattt ccttttcaag caactctggt tcaccataga caatatctag tctaagcttt
    31381 tcaatcactt cttttactaa aaccgacatc atttcctcct tcaaatgagt tcttctctct
    31441 attatatcaa attgtaggag gaagtttcag atttttgcag gctttggagt atttatttaa
    31501 aagaaaaagg actagatttc tctagccttt cattgcaatt agaatttttt acgtttacga
    31561 gctacttctg atttacgttt acgttttaca gaaggttttt catagaattc acgtttgcgt
    31621 gtttcttgaa gagtaccagc tttagtaacc gcacgtttga aacggcgaag tgcgtcgtca
    31681 agagattcat tcttacgtac tactgtttta gacatttttt tcactccctt caagttcaat
    31741 atctatttca ttctacacgt aaaaggaata attgtcaagc aaaaatgcgg tttaattttg
    31801 attttttctt ccatttatac aagagttgaa agcgttcaat agaacattgc ttttttattt
    31861 ttcgagtaag ctaagcgctt cagcatctgc gatgatggtt acatcagggt gattttggag
    31921 gctacttgca ggtaggttct cagtcactgg gccagatact gttccggcaa tggcttctgc
    31981 tttcgactca ccgtaagcaa aaagaataat agacttggca tccaaaatgt ttttaatccc
    32041 cattgaaata gcttgggttg ggacgtcttc aatcttggca aagaagcgtg cattggcttc
    32101 aatagtagac tggtcaagtt ctactagatg cgtttgactg tcaaatggag taccaggctc
    32161 attaaagccg atatgcccat tgcgaccgat tcccaagatt tggaggtcaa ctggatggtc
    32221 agccaaaatt tggttgtagc gttcaacttc agcttcagca ttgtccttaa caccacgagg
    32281 caagaaactt tctttaaatg gtttttggtt gaacaagttt tcttgcatga agtaacgata
    32341 agactgtgga ttgtccccat caaggcccac atactcatca aggttgacac tggttagatt
    32401 tgaaaaatca aggttactct caacaatttc cttgtaaaat tcaagtgggc tacttcctgt
    32461 cgcaagtcct agagtttgag ctccattagc caatttttcc ttcaaaatct caaaagcaac
    32521 ttttccacct tgaacttggt tttcaacttt aataactttc atcttttcat cctccatttc
    32581 tatctatatt tattatatgg tatagaccaa tttttgtcaa gtgaaaacga tttaatttct
    32641 aaaaaaagag cgtccaaact tgaaacgtgt tataatggat aggattagaa cttagaaaga
    32701 atgaacagat atatgaatac agctgatttt gatttccact tgccagagga attgattgcc
    32761 caaacgcccc ttgaaaaacg tgatgcctcc aaactcctca tcgtcaaccg tgagacagga
    32821 gaaatgcaag ataaacactt ccactctatt attgatatgc tggaacctgg tgatgccctt
    32881 gtcatgaacg acacccgagt tctccctgcc cgcctctatg gtcaaaaagt ggagacagga
    32941 ggtcatgtgg aacttctcct ccttaagaac actagtggag acgagtggga agttctggct
    33001 aaacctgcca aacgcctcaa ggtcggtact cgtatcagct ttggtgatgg ccgcctcagc
    33061 gctgtcgtta cagaagaatt gacccacggg ggacgcattg tccgctttga ataccaagga
    33121 attttcctag aagtcttgga aagtctggga gaaatgcctc tgccacctta tatccacgaa
    33181 aaattagatg accgtgaacg ttatcaaacc gtctacgcca aggaaagcgg ctctgctgca
    33241 gcaccgactg ctggtcttca cttcaccaaa gaactgctgg cagaaatcca agctaagggt
    33301 gttcatctag tctatctgac tctccatgtc ggactcggaa cctttagacc tgtttctgtg
    33361 gataatctgg acgaacacga aatgcattca gagttctatc aactttctga ggaagctgct
    33421 gccacccttc gctctgtcaa agaaaatggt ggtcgcgtca tcgctgtcgg aaccacttct
    33481 atccgcacct tggaaactat tggttccaag tttgatgggc aaatccaagc agattctggt
    33541 tggaccaata tctttatcaa acctgggtat gagtggaagg tcgtggatgc cttctcaacc
    33601 aacttccatc tgccaaaatc aactctggtc atgttggttt ctgcctttgc aggccgtgaa
    33661 ttagtcttag atgcctacca ccatgcgatc caagaacact accgcttctt cagttttggt
    33721 gactccatgt ttatttattg agaaagaatt tctctaaatc ttctaatacc aataaatcgc
    33781 taagatatta tttcaaagaa catctacaat tgaaactcta gctagctgta gaagaggcct
    33841 agtacattga aattaaaatg cttcccccta gcttcgaaaa tattgccata gattgcgttg
    33901 actctccaaa ttgattcatc tatattttat ttcagcttcc tatattttct tcgctgtttg
    33961 taaatcaaaa tgcaagacac atgagtagca ccatatttgt tactcttatc tgtcctctca
    34021 agagactatt atgagttatt tcagaatcat tcactacttt gaccctgact ctccttagtc
    34081 tcaaaatcaa agacttatac tcttcaaaaa tctcttcaaa ccgcgtcaac gtcaccttgg
    34141 attatatatg tgactgactt cgtcagttct atctacaacc tcaaagcagt actttgagca
    34201 acctgcgact agttttctag tttgctcttt gattttcatt gagtattaaa caaaaagtga
    34261 acaaagctga attctaatgt acagaagact aggcttgttc acttttttat agtcgctata
    34321 agatgacctt atctatagct ttttatatat aattatatat tcagacatac tattatcaat
    34381 tttgtcgcag ggaggaatct gttaacgcac ccattcacca ttatcattga ctctatagcc
    34441 atctatactt gtattgaccg ctaactcacc cgatgcattt acataatacc atttaccacc
    34501 aacttggaac cattgattga ctttcataga accattgctg ttgaggtagt accatgaacc
    34561 attaacttgt acccaacctg ttgccatgga gccatcagta ttataaaaat accacatacc
    34621 attttcttgt ttccagcctg ttgttggagc aactgcttta gctggttcta ctgctacatc
    34681 tgttccttgg ttagatgtaa cagatacagg atatgaagga atagatgatt gctcaggaac
    34741 aacaactttt tcaggttctc tcgtccctct ccttatacgt ctttttacca tctctttagt
    34801 aatttgacga gaagtagttt cttcaattgt tccatcacgt tcatctacag catagattgt
    34861 agtaagagta attttaccaa tttctcctac ttcttgacct ttatcaagag ttgggtcatc
    34921 gagatattct gtttcgattg gaatttcttg gacaagaact tggggcttgg ttcctttttt
    34981 aacaactctt gtttgagagt cttctttttg acttaaagta ctctcagtta cttgtccact
    35041 ctttccatct acatcataag ttatcgttgt aactgttttc ccattctttc ctagagtaat
    35101 ctcttgctcc tgtcctgcag aaaggtcatt gtctgcttca tattcagtag taaatggaac
    35161 aagaacttct tcaaccttgc ttttagctgg aactttgata actgtatccg tggcttcttt
    35221 tctatcaaca gtaacctgtt cggtaacata accagtctct ggattaacat cgtaggtcct
    35281 tgtcgtagtt acatagccat cctctccatc aattgtaaca ggattttcac tacggtcttt
    35341 tgtttcatct ttttcataac gaattcgcgt acttgaaatt ttcttggtta ctaccttagg
    35401 tttagtcgct acttttacaa taatatcccc attgtcagcg tcatcatact ctattccctc
    35461 ttctttatct ctagtatcat ctctgacata ttgaatccca tcagcagcat gaacaaaact
    35521 tgtattcaga ttcctcctaa aaataaagtt agcccgatta ccgcagaacc aaaaatcttt
    35581 ccgagtttac gtattgcata gcgcttatta gtattagatt ttgccattac atcctacttc
    35641 tagtatagca tcttttctat caaacgttaa acaatatact ttatatataa aatagactta
    35701 gaatgatata ttgattactg aactaacact ttaactatat cgtaatcaat ctcatatata
    35761 aaggattgca gacatcttat ctaaatacat gctaatatat ttagatacaa acattccaac
    35821 ttgataattt tcactcatc
//
LOCUS       DAVLDI010000018        34745 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLDI010000018 DAVLDI010000000
VERSION     DAVLDI010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.018"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            265..501
                     /locus_tag="VXD01_000874"
     CDS             265..501
                     /locus_tag="VXD01_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV0601303.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            732..2018
                     /locus_tag="VXD01_000875"
     CDS             732..2018
                     /locus_tag="VXD01_000875"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV0601304.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(2260..3408)
                     /locus_tag="VXD01_000876"
     CDS             complement(2260..3408)
                     /locus_tag="VXD01_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0601305.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(3582..4394)
                     /locus_tag="VXD01_000877"
     CDS             complement(3582..4394)
                     /locus_tag="VXD01_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0601306.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYAKYYSN
                     LSTKELREELEEYGLKVFKYQDLDFFNIELVPEVDNRYDPNAIKVLIFDNHVGYVPAT
                     IAKTIRKYFDNKKYNFVIEGEIKGGPYKEWDEYEEKVVTNNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNISNKEVTETEAIETKTTETEHIEQNIVSDSVADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            complement(4432..4812)
                     /locus_tag="VXD01_000878"
     CDS             complement(4432..4812)
                     /locus_tag="VXD01_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV0601307.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHSSGFYNPDTNVLAIDHNLAPE
                     QQIQVALHELGHKDHTRSEYQNARLRCENEADRNMIHHLVKDALESLDDPTEFDYLKF
                     MSYYNLKTMTNEVMVKEEYLALVN"
     gene            complement(4825..5088)
                     /locus_tag="VXD01_000879"
     CDS             complement(4825..5088)
                     /locus_tag="VXD01_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV0601308.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            complement(5088..5321)
                     /locus_tag="VXD01_000880"
     CDS             complement(5088..5321)
                     /locus_tag="VXD01_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601309.1"
                     /translation="MTITINFTEKNSYITDYLTKHGIDTTTMDFDDFMVLMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLSREDIA"
     gene            complement(5321..5689)
                     /locus_tag="VXD01_000881"
     CDS             complement(5321..5689)
                     /locus_tag="VXD01_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0601310.1"
                     /translation="MFVAFDKIKELADKQGISINILEEKLGYGTNTLYRLKRSNPSSK
                     VLKEIADYFNVSADYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            complement(5995..6477)
                     /locus_tag="VXD01_000882"
     CDS             complement(5995..6477)
                     /locus_tag="VXD01_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601311.1"
                     /translation="MKSSFFHYLKEIILYGVLVPILTVIVGFHLFTTFYPISDSLLTD
                     FLKAFTEQRILAIVFVLILCFIFFGSIYYCISCGRNRKLIPDKVYTQITTYISSVGLG
                     TAVIAVATLTLTELQFSILTGWIAFIALLLPLLKFKVQYSTYQSSDNVAQKTTENKAN
                     "
     gene            6532..6735
                     /locus_tag="VXD01_000883"
     CDS             6532..6735
                     /locus_tag="VXD01_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0601312.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQAELAKQVSVTSSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            6752..6949
                     /locus_tag="VXD01_000884"
     CDS             6752..6949
                     /locus_tag="VXD01_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601313.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            6960..7121
                     /locus_tag="VXD01_000885"
     CDS             6960..7121
                     /locus_tag="VXD01_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601314.1"
                     /translation="MNELVWFYFVVIINLIIGFATYYASKRDREKRINGFKKIQDDEL
                     ERVRNKFNL"
     gene            complement(7116..7541)
                     /locus_tag="VXD01_000886"
     CDS             complement(7116..7541)
                     /locus_tag="VXD01_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601315.1"
                     /translation="MEYQALIQPVISIILAIISGLWSYVASKANNKAEIEKQAKEHSH
                     TVEKLEREFHHQIDTLKQQHAFELEKIKQAHELRLQELEKVSQLDTETDKSMKMNDLT
                     YKVFTGEVDFDKALKIANKASNSKQNLNKRFIQKTSKKS"
     gene            7595..8305
                     /locus_tag="VXD01_000887"
     CDS             7595..8305
                     /locus_tag="VXD01_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HEV0601316.1"
                     /translation="MNEIFNFHGQEVRTLTIDNEPWFVGKDVADILGYSKARNAIALH
                     VDEEDALKQGIPTSGGTQDMLIINESGLYSLILSSKLLQAKEFKRWVTSEVLPAIRKQ
                     GGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAQSLLKKRKAR
                     VVACLGGIDSPAYADKVFSQSVFRQAEIDFKDHFNISRYDLLPKKHADAALAYWMTWE
                     PSTNTKMKIMKLNSFDDV"
     gene            8319..8576
                     /locus_tag="VXD01_000888"
     CDS             8319..8576
                     /locus_tag="VXD01_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0601317.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCE
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            8662..8982
                     /locus_tag="VXD01_000889"
     CDS             8662..8982
                     /locus_tag="VXD01_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601318.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIQVRNHAYERGREDKWQEIRKNIRREFKGFTYDNEPPVGLRPEPLALPEPKQSA
                     IRLL"
     gene            8998..9291
                     /locus_tag="VXD01_000890"
     CDS             8998..9291
                     /locus_tag="VXD01_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601319.1"
                     /translation="MEELIEWLETKEKLNREMISDEETSDFNLHLENDNDTMFMIKEY
                     LNDYNKLAKDYRILSSENRLLKLEKMELEGRYIYEDMRMKYRANRRKWGARYV"
     gene            9284..10072
                     /locus_tag="VXD01_000891"
     CDS             9284..10072
                     /locus_tag="VXD01_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV0601320.1"
                     /translation="MSEIKWIKITTDIFDDEKICLIDALPDPDAILVIWFKILTLAGK
                     HNSNGLLMMTDKVHYTDEMLATIFRRPLNTVRMAIGVFEQFGMIEIIDGIISLPNWEK
                     HQNVDGMEKIKEQTRNRVAKYRKKQKNLALGNVTVTDGNALEEDKDKNRLDKDKNKKR
                     ITTTSSGSEENILELFQSEFRRLLSGFEIEEINHLLNENDVDLVKEALKTAINSGKPN
                     IKYIGGILRNWQMNNVTTVEQVRQSEKKNKDKKEEQEAKDEWGY"
     gene            10060..10218
                     /locus_tag="VXD01_000892"
     CDS             10060..10218
                     /locus_tag="VXD01_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601321.1"
                     /translation="MGVLELIEQFEIDYYPLSYEKKTLLADQPIHQVVACLSEMASWH
                     ECGGRLVW"
     gene            10212..10982
                     /locus_tag="VXD01_000893"
     CDS             10212..10982
                     /locus_tag="VXD01_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0601322.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEVLKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAVVKALSEYTKEIAIFINVTDFLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            10997..11191
                     /locus_tag="VXD01_000894"
     CDS             10997..11191
                     /locus_tag="VXD01_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601323.1"
                     /translation="MFILKHGTREDKPFLRSAIISVTGLDISCSEEKKAMRFISRAAA
                     LQVSKALRGSFGNFYPVEVE"
     gene            11191..11418
                     /locus_tag="VXD01_000895"
     CDS             11191..11418
                     /locus_tag="VXD01_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601324.1"
                     /translation="MLELYFVYNGHCKFYLGTFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
     gene            11545..11712
                     /locus_tag="VXD01_000896"
     CDS             11545..11712
                     /locus_tag="VXD01_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601325.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            11699..11908
                     /locus_tag="VXD01_000897"
     CDS             11699..11908
                     /locus_tag="VXD01_000897"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601326.1"
                     /translation="MKYDKQAEIDGLKRTIEQNEEKIIEYSKPCDARKRRIRALERDL
                     LRKKNKELRRKVEELEGNGRVKSKS"
     gene            11883..12209
                     /locus_tag="VXD01_000898"
     CDS             11883..12209
                     /locus_tag="VXD01_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601327.1"
                     /translation="MEELNQKVNAVYNWTVEDGKPKPPKQDLPQAVKDRADYFWEMAE
                     DGMTFMGAMECIFADEKPTDYELGATKGWLPKSKEFDDWVGYSPSMTQVVIAVYLIYG
                     GSEDET"
     gene            12199..12672
                     /locus_tag="VXD01_000899"
     CDS             12199..12672
                     /locus_tag="VXD01_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV0601328.1"
                     /translation="MKLNELIKKYKKLEGVWNAEGAELARQIFLQDLEQLDKQQPVKV
                     KKFVADFIAEQKKLGHTLSYSIDASMSDIVAEWYWDNSELFALAWIFGCEVEEEKRYT
                     VVTKATKQPLYYNAMDKKLFFSMGGLATKFTRKQLKEADFGWVFDCPGIEIEEVE"
     gene            12672..12959
                     /locus_tag="VXD01_000900"
     CDS             12672..12959
                     /locus_tag="VXD01_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601329.1"
                     /translation="MTQTLEEGMKNQSKCIKVPREIRPFDIGYRIVNKYGQALALRNG
                     ASIFDLPFLAEKAIEKEFGKNDPDFDIGKHSVEEVAIVNLSKFHSYFEEVE"
     gene            12959..13132
                     /locus_tag="VXD01_000901"
     CDS             12959..13132
                     /locus_tag="VXD01_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601330.1"
                     /translation="MEDEQNILEIQLILGKQVLEIVLDLLKDDSKTGVVLPLNINDRE
                     FTITVEKEVTDRD"
     gene            13195..14327
                     /locus_tag="VXD01_000902"
                     /pseudo
     CDS             13195..14327
                     /locus_tag="VXD01_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069621.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            14429..14707
                     /locus_tag="VXD01_000903"
     CDS             14429..14707
                     /locus_tag="VXD01_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601331.1"
                     /translation="MKRLGIIIGAVFVIVVSPFVVQYGWNEIITTIVPVGKITVWQAL
                     GMDALLSFIWPVLSSKKESEEDYSYAVKSSISKIITCAFLIWLASLFI"
     gene            14719..15129
                     /locus_tag="VXD01_000904"
     CDS             14719..15129
                     /locus_tag="VXD01_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601332.1"
                     /translation="MIPKFRGLSIDEKSKGEWQYGHLIEDRGRAFIINEVVEANEQYI
                     TIGSWCPVNPATLGQSTGLRDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTYIGGMP
                     AVYLKGFGDGYAWTEYEEIIGNVYENPELLEVNE"
     gene            15266..15667
                     /locus_tag="VXD01_000905"
     CDS             15266..15667
                     /locus_tag="VXD01_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0601333.1"
                     /translation="MKKLSDEDLKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     SVGISKPTETIAVRIADDPTLKFLEGFKAIINKLLINLVDEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAILKGEL"
     gene            15858..16400
                     /locus_tag="VXD01_000906"
     CDS             15858..16400
                     /locus_tag="VXD01_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0601334.1"
                     /translation="MEFVSPIKDNDDIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEGKPFHHFLFKSRQGQNK
                     AITRERAYQIIHEAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            16731..17051
                     /locus_tag="VXD01_000907"
     CDS             16731..17051
                     /locus_tag="VXD01_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV0601335.1"
                     /translation="MYNKPIRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            17189..17581
                     /locus_tag="VXD01_000908"
     CDS             17189..17581
                     /locus_tag="VXD01_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HEV0601336.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYADMGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEVLKFKNEIKKKRVTGNG"
     gene            17574..19304
                     /locus_tag="VXD01_000909"
     CDS             17574..19304
                     /locus_tag="VXD01_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEV0601337.1"
                     /translation="MGNLDKAKEYAQHVLTHREEHCEENILAAERFFRDLENPTFEMD
                     EDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVNYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYH
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     KMREKGFKIAAVGMDRKFGREFLTKMKQARFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQALANLG
                     KGGDVMRFFD"
     gene            19312..19530
                     /locus_tag="VXD01_000910"
     CDS             19312..19530
                     /locus_tag="VXD01_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601338.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            19548..20750
                     /locus_tag="VXD01_000911"
     CDS             19548..20750
                     /locus_tag="VXD01_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV0601339.1"
                     /translation="MGIFEKFWKRNKPSKSINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCEHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDEVVHFV
                     INPDPDILYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            20734..21309
                     /locus_tag="VXD01_000912"
     CDS             20734..21309
                     /locus_tag="VXD01_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HEV0601340.1"
                     /translation="MQKRNSYRATQFQTREEESGDLVLSGYFIKFDEETELWRGYHEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFKL"
     gene            21306..22472
                     /locus_tag="VXD01_000913"
     CDS             21306..22472
                     /locus_tag="VXD01_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEV0601341.1"
                     /translation="MNKALIFGARMRAKATKVVELEETIEELNKRSVVELEKLDRAKN
                     DEEVLAVEKTVDGLQREIEEKEAEKVQLENEIDELDKQIKEQNRKAPTPGKMEERGGK
                     TLGQREAFNHYLRTKEARADGFKSAEGEAIIPVELMTPKEAKQDKTDLTSLVNIVNVK
                     NASGKWSVVKLTDQEMNTVEELEENPELAKPTFTKVNYEIQTRRGHLPVSQEFIDDAD
                     YDVMGLVAKQTKNQERITKNKEIAKVLKTATSKSAAGLDGLKDILNVELKTYYNATIV
                     CTQSMFAALDKIKDKDGRYMLQTDITSPTGYKFAGRVIVVYPDDIIGESKGDLKAFIG
                     DVGEFATLFDRAQTTVKWQDDKIYGQYLATANRFDVVKVDGDAGFYVTYTDAVL"
     gene            22484..22753
                     /locus_tag="VXD01_000914"
     CDS             22484..22753
                     /locus_tag="VXD01_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601342.1"
                     /translation="MVYKVIRPFKDLRDPKKHCYKVGDNYPRVKHKLDKEFAETLLNG
                     ANSAGSIFLMNVEDKDMSKDDTLTTEVEKEETKVVDGKPEEGDEE"
     gene            22756..23037
                     /locus_tag="VXD01_000915"
     CDS             22756..23037
                     /locus_tag="VXD01_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601343.1"
                     /translation="MDNVQLLELLKLKLGIATKLRDKPLEKIIEAVKTELEDNLGVLL
                     DLDSSEDQMFVVDFAAFRYEGGVDMPRHLQWRLHNLQIASKKEVKNVES"
     gene            23024..23323
                     /locus_tag="VXD01_000916"
     CDS             23024..23323
                     /locus_tag="VXD01_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEV0601344.1"
                     /translation="MWNHEITLISKEVTGKDKLLQPISEDVEVTLLCRKKRVTRSEFY
                     QANQVGLKPSLVVEIRNFEYENQELAKFEGKQYHILKTYPIDSEILELTLSEVLK"
     gene            23320..23679
                     /locus_tag="VXD01_000917"
     CDS             23320..23679
                     /locus_tag="VXD01_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV0601345.1"
                     /translation="MSLTSDLANEIAKAMAEYSAEVEDKIDLIAEDVVNEAVTELKAT
                     SPKRHGKYARNWRFKKNAKGSYVIYNAAPTYRLTHLLENGHVLRNGGRSRAFPHIKPV
                     EEKVKENFEKRIKEIGK"
     gene            23676..23999
                     /locus_tag="VXD01_000918"
     CDS             23676..23999
                     /locus_tag="VXD01_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601346.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPDLPYLVYYESSPVINS
                     ADNTVNHQIKSVTVELVFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            24011..24589
                     /locus_tag="VXD01_000919"
     CDS             24011..24589
                     /locus_tag="VXD01_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0601347.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAIDLTL
                     DTKGETTTIKADNKDYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAMMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVAA"
     gene            24601..25020
                     /locus_tag="VXD01_000920"
     CDS             24601..25020
                     /locus_tag="VXD01_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601348.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATNIDISMLSDFDMTFFNRLFWTFAKSANPHIKPYEQFFMEME
                     VFPIQEVGPVLMEMLNASMTTKKHQMNQNQLAKKSSQ"
     gene            25298..28057
                     /locus_tag="VXD01_000921"
     CDS             25298..28057
                     /locus_tag="VXD01_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEV0601349.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALNENGSATQNNKNQLKELQNEQSQLASEMSKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANRM
                     EAELNQAKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAEALDLTSRATRAAADGAAFYDKSIESVTESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFSSLPAPVKDFVVILGTV
                     VTAVGVIAPIFLSLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILEVINAVVSEISNFVMSIFGTVVAWWTENQELIRASAETVWN
                     AIYTVISTILEILGPLIQAGWDNIQLVITTAWEIIKTVVETAINVVLGIIQAVMQIIN
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNIWNSIKDTV
                     SNVLNAISSTVSSVWEGIKSTISSAINGARDAVSSAIEAIKGLFNFNISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADISRIADEVAQRIADELQRRRQL
                     RGGFA"
     gene            28054..28776
                     /locus_tag="VXD01_000922"
     CDS             28054..28776
                     /locus_tag="VXD01_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0601350.1"
                     /translation="MIKHNELVIDGVRTSSFPFKIIVHDSPSIALGESKTALLEHGGV
                     SGAIVQTNKHRELVKKSYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVTDLEEVQPGLYMTKATFTCHPTKYFKATDTQRLTRSGTLNVQGSALAFPKITIVG
                     QSVVETSFTIAGQVIRLEKLSESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            28777..>34745
                     /locus_tag="VXD01_000923"
     CDS             28777..>34745
                     /locus_tag="VXD01_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV0601351.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKETMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVENNDHLEITAYHISDDVMQRSITPVS
                     VTSQSCGMALSRMVQNTKTALGDFSFNSDIQDRRTFNTTEIETLYSVLLDGKHSIVGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKDYQRTKNSQNVVTRIHARSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKSVEELQKWAQAKFSNEGIDKISDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDVFKKAIAYEFDALKEEYISLILDDKAGAGG
                     SRTSGGLSSAAYAILGVTESAQEVALEKALQNADLDFDHKAGLLRQEISDGIELAKAK
                     AEEVKQELSDTINQRFNSFDNGPLKEAKRKAEEALRNAGASSSLAQESKRIGLDSVAR
                     LEAFKSQTTSAQTALSGDLDALKRTIVNDIRPKQAQVEAEIAKQVEALVQTKKELSGA
                     STLLAQEAKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKRTIANDIRPKQAQAEAE
                     IAKQVEVLSRTKNELAGVKSAQATYEETTTRRLSELTNLSNGKASKSELTQTAEELAS
                     RIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDYVRISFDV
                     TFPVALVNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSEDYQTNNVF
                     IRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSVVESNFKQRADSLDA
                     GVSRLTEGLRTKADISALNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQ
                     EILNATKDKASKSELTQTAEELASKIASVHLGRRNLLKGTKELARYKPVSEYNGFKVI
                     RTVAGATRYQDSYVERTVIPTAGTEYIAIFYARASENDYPVRCHFYNPNTVVSSENSS
                     GYKSRSSDGLSIIRLSTDWQLCWVKWTQTATDQAKTVIIGRHGPQVGGKEGVWVEICA
                     PAIFEGNLAGDWSPAYEDQDERVSAVESNFKQRADSLEAGVSRLTEGLRTKADISSLN
                     VTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKASKSELTQTA
                     EELSSKIASVQVGGRNYIRGTKRMMLARGLWASGTFRPSGAGTAKTIDVSDSPATGFD
                     KAIRLTSSNARDQIGIAQDGFYISQGTYTMSCWVKGRRGQKVKLQTYWQVNDNSGISP
                     IFTLKDENWTKLSFTSARNRAGVASIGYVYLVNAEVGEYLDVLAPQLEDGSLATSSKE
                     APEDIEGQISTVESTFKQRADSLAAGVNRLTEGLRTKADISALNVTAENIRQSVKSLE
                     TDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKASKSELTQTAEELASRIASVQASG
                     RNLFLNSLFKQDIPKTGIWTTSTYTATIDSESKYLGHKALKIIGLNPSGRDGGNPKVT
                     YPALGQFGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRY
                     VVHIPKGWTNESKQTTNEWLFNFNQEGTIWIWMPKFEISDVDTSYSEAPEDIEGQIST
                     VESNFKQRADSLEAGVSRLTEGLRTKADISALNVTAENIRQSVKSLETDTQNKLNQKL
                     SQAEFEVRAGSIRQEILNVTKDKASKSELTQTAEELSSKIASVQVGGINLLRNTASLL
                     IGDRSKGCWMSASGGNGRAISVEVLDPPKKMIKNMIRVIENTNGGNKDLTQLVRLRIG
                     EKYTISCYARIASDSPNANVNLLFRSWANNTDLNRKFQKSISHKNWQKYSFTFTADAI
                     ENSIQFGQSGAGIIEICAPKIESGTLATDYSEAPEDIEGQISTVESTFKQRANSLDAG
                     VSRLTEGLRTKVDISALNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQE
                     ILNATKDKADKTLVVSEAGKLREEFSKMKVGG"
BASE COUNT        11023 a         5884 c         7982 g         9856 t
ORIGIN      
        1 tgaatttttt tatactagaa aatcagaacc ataataccta tataaaaata ttatagtttt
       61 aataggattt acccaaaagt tttaaggcgg tctttttaga actttaattg tttgaaattt
      121 aggtagcaaa tttgtttcta ttttgtcaac ttttcctatt tttatcttgt tgaggctggt
      181 attttaacaa ttcaggaatt gatagtgaat gtgtaaaatt ttttgttaga ataagtttat
      241 aaaaaagaaa aggagtattt gattatgtta caaaaaattt atgagcagat ggctaatttc
      301 tatgatagta ttgaagaaga gtatggtcct acatttggtg ataattttga ctgggaacat
      361 gttcatttta aatttttaat ttattattta gtaagatatg gcattggttg tcgtaaggat
      421 tttattgttt accattatcg tgttgcttat cgtttgtatc ttgaaaaatt ggtaatgaat
      481 cggggtttta tttcttgttg aggtaatttt agtaaatttc cgaactaatt tactctttta
      541 tggaaagatg atagtaaata gctagtaatt tttctaaatc attttttaat agttggaaat
      601 agcaaatctt tctattgttt cttcttgata aaaaggcgat tttttattat aataaattgt
      661 aagatataat tgcaggtgag agtcctgcca tgtatgtgag aaaggaagag cctgagggct
      721 cagacaagat tatgacttca gttgttgttg taggtaccca atggggtgat gaaggtaaag
      781 ggaagattac agacttcctt tcagcgaatg cagaagtgat tgcacgttac caaggtggtg
      841 ataatgctgg tcacacgatt gtgattgacg gtaagaaatt taagttgcac ttgatcccat
      901 ctgggatttt cttccctgaa aaaatatctg tcattgggaa tggtatggtt gtaaatccta
      961 aatctcttgt aaaagagttg agctatcttc atgaggaagg tgtaacaact gataacttgc
     1021 gtatttctga tcgtgcgcat gttattttgc cttatcatat cgagttggat cgcttgcaag
     1081 aagaagctaa gggcgacaat aagattggta cgacaattaa gggaattggt ccagcttata
     1141 tggacaaggc tgctcgtgtt ggaattcgta ttgcagatct tttagataaa gatattttcc
     1201 gcgagcgttt agaacgtaac cttgctgaaa agaatcgtct ttttgaaaaa ttgtatgaca
     1261 gtaaagcgat tgttttcgat gatatttttg aagaatatta cgaatatggt caacaaatca
     1321 agaaatacgt gatagataca tctgttatct tgaatgatgc gcttgataat ggcaaacgtg
     1381 tgctttttga aggtgcacaa ggtgttatgc tagatatcga ccaaggtact tatccatttg
     1441 ttacgtcatc aaaccctgta gctggtggtg tgacaattgg ttctggtgtc ggtccaagca
     1501 agattgacaa ggttgtaggt gtatgtaaag cttatacgag tcgtgtagga gatggtcctt
     1561 tcccaactga gttgtttgat gaagtgggag aacgtatccg tgaagtgggt catgagtatg
     1621 gtacaacaac tggtcgtcca cgtcgtgtag gttggtttga ctcagttgtg atgcgtcata
     1681 gccgtcgtgt ttctggtatt actaaccttt ctttgaactc tattgatgtt ttgagcggtt
     1741 tggatactgt gaaaatctgt gtggcctatg atcttgacgg tcaacgtatt gactactatc
     1801 cagctagtct tgagcaattg aaacgttgca agcctatcta tgaagagttg ccaggttggt
     1861 cagaagatat taccggagtt cgcaatttgg aagatcttcc tgagaatgcg cgtaactatg
     1921 ttcgtcgtgt gagtgaattg gttggcgttc gtatttctac tttctcagta ggtcctggtc
     1981 gtgaacaaac aaatatttta gaaagtgttt ggtcctaaga gatttttaag atttgtttaa
     2041 gataggtcgg gtatactata aacggttaca agaagacctc ctaacttgtt gtaacaaata
     2101 tcctaaactt ttctttttca taataatctc ccttaactcc acccaatcag gtggagtttt
     2161 ttagctttat ttcaggcttt tggggactat tctaaaaata atttttcgat atttttcggt
     2221 atttttcgga ttttggtcgg ggaattggcg gggacttttt tagcgaatat gactaagaaa
     2281 taggtctgtt gtcgcttcag caagttcgtc ctctacttga ttgtaacgat ccgtcatata
     2341 aacctttgta tgccccagcg cctggcttaa ttgttcaagc ggaacccctg caataatgct
     2401 ttgagtcgtg aagaagtggc gcatcatgtg aggtgttaca tgcaatcctg ttgcttcatt
     2461 cactagattg aagtttctat ttagctgatt tggattgatg agaccacctt tctcgttgat
     2521 agttatataa tccttgtgct gttccttgat aattcctaac tttcgcttaa tcttagaagc
     2581 ttcagctatc agataataga tcaggtctgt tccgatatca tcaaggcaga catatcgctc
     2641 tgaatccttc gttttaagcc ctcctttccc ttttaaggtc tggttgcttc gactgtctct
     2701 aagatgcagt atagcccgtc cgctgtcgtt ctgagtgatg tccattggac gcaatccaaa
     2761 gacttctcct cttctcaatc caaaaattgt cagataggtc agagcgtaga attgttttgg
     2821 cataatctct tctgcctttg ctatccaagt cttgaactct ttgagagtca ctttcttgtt
     2881 tgcagcaggg atatcactct ggccgatgaa aacacctttc aagcgatttg agagcagatt
     2941 accatttttc acggcatcat tcagcaatgc catgaagctg gaattgaggg tttgaacagt
     3001 gtatctggta tggttctgca acttttcagc gataaatagt tcatactcat ttctatccaa
     3061 atttttaagc aggatagaac caaactttgc cttgatatgg ttcttataga gattgtcatt
     3121 gaggtagtag gaagtgtcat tccagcgccc tgttgacaat ctcttttcgg aatagatatc
     3181 ccaatattga tcaagcgtta gattcgtatt gatacctaat tcttgttctt ggatttgttg
     3241 ctcaagctct accaaggctg cacgagcttg agggagagtt gtgaaaccac ttttactttt
     3301 ttctcttttt ttacctcgga agaaaaaaga acgtctgaca tagtaacgct tgcctttagc
     3361 agtctcatag taatagatat ttgggtattt tgttttatta tatttcattg tattctcctt
     3421 gtttatcggc ttctggacaa ggtctaaaca ttgagaatat tgacatcacc cctttcatgg
     3481 tgtaaaatag ggtatagaaa agaggccttt ttaatggctg attttttata agggtaagct
     3541 tcacaatcaa actttggcga gggcgattgt ggggcttttt tttattttct gaatagtttg
     3601 tatagtttat acaaactcca agctgtcaaa gggactgcaa ggaatggagc gattggaata
     3661 ccaacaactc caaaaaagac taagaaaaga tacagtgctg aaaatatgat tttattggca
     3721 ggaagttttt tcttaggaga tgtttctgaa agattaatct cgtttactat atcagcgaca
     3781 ctgtcactaa caatattttg ttcaatatgt tcagtttcag ttgttttagt ttcaatagct
     3841 tcagtttccg taacttcttt attggaaatg ttatcatcaa ttatctcaga tgattcgctc
     3901 tgaattactt ctttttgtga agaatcaaca atggtaaggt aaatttcaaa accaacatcc
     3961 aaatcattat ttgtgacaac tttttcttca tactcgtccc attctttata tgggccacct
     4021 tttatctctc cctctattac aaagttatat tttttattat caaaatattt tcgtattgtt
     4081 ttagcaatgg ttgcaggaac atatcctaca tgattatcaa atatcaaaac ttttatagca
     4141 ttaggatcat atctattatc tacttctgga acgagctcaa tattgaaaaa gtctaaatct
     4201 tgatatttga aaactttcag accatattct tcaagttctt ctctaagttc cttagttgat
     4261 aaattgctat agtactttgc atattctggg attccgttat cttcagcaat catattgcaa
     4321 gcttctttta ctgctttttt atattttgtc actccagcga ctctgaataa tattttttca
     4381 acagtctttt gcatatattt cccctctata taaatatctt caatgcaatt tttaatttac
     4441 taatgccaag tactcttcct tgaccatgac ttcattagtc atagttttta gattgtagta
     4501 agacatgaat ttgaggtaat caaactctgt ggggtcgtct aagctttcta gtgcgtcttt
     4561 cacgagatga tggatcatat tcctatcagc ttcgttttca cagcgtaggc gagcgttttg
     4621 gtactctgag cgtgtatggt ctttgtgtcc gagttcgtgt agggcgactt ggatttgttg
     4681 ttcaggagct aagttgtggt caatagcgag tacgtttgtg tctggattgt agaaaccgct
     4741 actgtgccag tttgaaccgt cgaagagaca aagctctact tgatattctt cgcagagttt
     4801 agcgagtgtc atagttctcc ttcgttattt ataaacatct ctgcggtggg cgatttccac
     4861 ggctaggacg actagtttat cgtcttggat atcacagatg atgcggtaat tctctactct
     4921 gtatcgccag taacctgcaa ggttggcttt tagtgctttt ccgtgttgtc gtggattggt
     4981 cgtgttttca atgtttttag caagccagga taggatttgt tttctggttg gggtatctag
     5041 ttttttaagt tgcttgagag cttttttatc aatatctagc cgatacatta agcaatatcc
     5101 tctcgagata gtcctagttc atccaagacc tcatccatgg tataagtagc tgggtcggct
     5161 aaatactcca tataggcttg gtcggctgct cgtgcgtctt cgatatcttc catgagtacc
     5221 atgaagtcgt caaaatccat ggttgttgtg tcgataccgt gtttggttag gtagtccgtg
     5281 atgtaggagt ttttttctgt gaaattgatc gtgatagtca ttagcgttct cctttgcttt
     5341 tgaagtgggc ggatagaacg gatgtgatga agtcgatatc atcttcattt agtggttttc
     5401 cgtcaaataa catggtgttg gctgctgctt tgcgtaagtc tatgatttgt ccatttactt
     5461 gagcaaattc atcacttcca gcgatagcag gattatctgt ccgtccgagt aggtagtcag
     5521 cacttacatt aaaataatca gctatttctt ttaaaacttt tgaactagga ttacttcttt
     5581 ttaatcgata taaagtatta gttccataac caagtttttc ttctaaaata tttatagaaa
     5641 tcccctgttt atcagctaat tcttttattt tatcgaatgc tacaaacatt aatttttcaa
     5701 cctttctaag caaacgaaaa ataattttaa aatatttgta gaaaatagtt gacttattta
     5761 gtcaaatgtt ttaaaataat attcgtaagc taaagagtta gcgaactaga caactaaaaa
     5821 ataaagcctt acaaaactga ttggcgtccg tttactgtag gtaaaactta cttttagtag
     5881 gtcttttctc tatgttttta ttttaaaaca tttgactaga gttgtcaaga agttcgctaa
     5941 ctttttagat aattttttaa aagaaagggg gagaggagaa tggtagagcc tttcttaatt
     6001 ggctttgttt tcggtagttt tctgtgctac attgtcgcta ctttgatagg tgctgtattg
     6061 gactttaaac ttcagaagtg gcaacaacaa agcgataaaa gcaatccaac ctgtaaggat
     6121 tgaaaactgt aattctgtga gagtcaaggt agcgacagct atcactgcag tccctaaacc
     6181 tacagatgaa atgtaagttg tgatttgtgt ataaacttta tcaggtatca attttctatt
     6241 tcgtccacat gaaatacagt aataaattga accgaaaaat ataaagcaaa gaataagaac
     6301 gaatacaata gcaaggattc tttgttctgt aaaagctttc aagaaatctg ttaacagtga
     6361 atcagaaata ggatagaagg tagtaaaaag gtgaaatcct acgataactg tcaaaatcgg
     6421 aactaggaca ccatataaga tgatttcctt tagatagtga aaaaatgaag atttcattat
     6481 tctcctccaa tcgtttttat tttaattata tcaaatttag aaaggaaaaa tatgagtaaa
     6541 gaactaaaga taatcaaggc taaaatcaaa actcgtttga ttgagctgga tatgactcaa
     6601 gccgaattgg caaaacaagt atctgtaaca tcatcagtta tttcagaact gctgaagtat
     6661 ggaaaaggaa gtgattatgt gaaagaaaaa gtcgtagata ttttgggtat tgaaaaccct
     6721 tgggaaaata gttagagcat gaggaaatag tatgaacaac gcagcgcaaa aagtaacacg
     6781 gattgacaaa gatgcctggg agattgctac ggagttggcg aacgagtacg gggtatctat
     6841 ttgtcacatc atcagtgaga gcgtccgcta ctgtgcagag aatgccgaat ttaaggagat
     6901 ggacgttgtc gttaaacgat tggtagtcgg cagtaaggtg ctggagtagg agggtggaga
     6961 tgaatgaact agtatggttt tactttgttg tcataatcaa tcttatcatt ggttttgcta
     7021 catactacgc tagcaaaaga gatagagaaa agcgcatcaa cgggtttaaa aaaatacaag
     7081 atgatgagct tgaaagagtt agaaataaat ttaatttatg attttttaga agtcttttga
     7141 ataaatcttt tatttaagtt ttgtttgcta ttgcttgctt tattagctat ttttaaagct
     7201 ttgtcaaaat caacctcgcc tgtaaaaact ttgtaggtaa gatcattcat cttcatagac
     7261 ttgtcggttt cagtatcaag ctgagatacc ttctcaagtt cttgcaaccg taattcatga
     7321 gcttgtttga ttttttcaag ttcaaaggca tgttgctgtt ttagagtatc tatctgatga
     7381 tgaaattctc tttcgagttt ttcaacagta tgtgaatgtt ctttggcttg tttttcaatc
     7441 tcagctttat tgttagcttt tgatgcgaca tatgaccata accctgatat tattgcaaga
     7501 ataatactaa tcacaggttg aataagagct tgatattcca taagatttct ccaatcgttt
     7561 tattttaatt ataccaaatt tagaaaggaa ctttatgaac gaaattttta attttcacgg
     7621 acaggaagtc cgtactttga caattgataa cgagccttgg ttcgtcggga aagatgtcgc
     7681 agacatccta ggatatagta aggctagaaa tgcgattgct cttcatgttg atgaagagga
     7741 cgccctaaaa cagggcatcc ctactagtgg tggaacacag gatatgttga tcatcaatga
     7801 atctggtctc tactctctca ttttatccag caaattgctt caagcaaaag agttcaagcg
     7861 ttgggtgaca tcagaggtct tgccagctat tagaaaacaa ggcggattta tccgagagga
     7921 cttggatgaa gatgctttca tcgctctgtt tactggacag aagaagttgc gtgagcaaca
     7981 agcgaccatg ctggaagata ttgactacct caagagtgag caaccgattc atccaagcta
     8041 tgctcagtcg ctactgaaga agcgcaaagc tcgggtcgtg gcttgccttg gcggtattga
     8101 cagtcctgct tatgcggata aggttttttc tcaatcagtc tttagacaag ctgagattga
     8161 tttcaaagac cacttcaaca ttagtcgcta tgacttgcta cccaagaagc atgcggatgc
     8221 cgctcttgct tactggatga cgtgggagcc aagcactaat accaagatga aaatcatgaa
     8281 attgaactca tttgatgacg tctagaaagg ggaagaagat ggacaatgtt ctactttcac
     8341 tgtctgaatg gattaaatct attatcaagg acacaatcac aaggctagtc gaaatagaaa
     8401 aagatagtga tcactatcca gagttgatgg atgtgaacac tacctgcgaa tttctaggaa
     8461 ttaagtatgc caccttttca gataattatc gttacttaaa gggatttcca aaggaattac
     8521 ctggtaagaa atggtcaaaa agagccatca aagaatggct ctctaatcaa atataataac
     8581 tttactaaaa ggcttctgga caaggtctta gcaaaattat ttgactatat tatagcacaa
     8641 aaagaggata aggagataaa aatgtttgaa ccaccgattt tagaccagct gatgggggtt
     8701 ggagccttac tgcttggatt tgcaggggct tgccgtcata tcaaattgca ggaacaacgc
     8761 aaggaagaag aaagacgaga agagcaagaa tttgcgtcta tgattatcca agtgcgtaat
     8821 catgcatatg aacgtggtag agaggacaaa tggcaagaaa ttcgcaagaa tattcgcaga
     8881 gagttcaaag gattcacata tgacaacgaa ccgcccgtag gattgcgtcc tgagccgtta
     8941 gctttgccag aacctaaaca gtctgcaatc agacttctgt aatgaggagg gcaggaaatg
     9001 gaagaattga ttgaatggct tgaaaccaaa gaaaaattaa acagggaaat gatttctgac
     9061 gaggaaacat cggactttaa cctacatcta gaaaatgata atgataccat gttcatgatc
     9121 aaggaatact tgaacgatta taacaagcta gccaaagact atcgaattct atcgtctgaa
     9181 aatcgtctac ttaagcttga aaaaatggag ctggaaggca ggtacatcta tgaggatatg
     9241 cgaatgaagt atcgtgctaa ccgtaggaag tggggtgcta ggtatgtctg aaattaagtg
     9301 gataaaaatc acaaccgata tttttgacga tgaaaagatt tgcctgattg atgccttgcc
     9361 tgatcctgat gccatcttag tgatatggtt caagattttg acacttgctg gaaaacataa
     9421 cagtaatggt ttgttgatga tgactgataa ggttcactat acagatgaaa tgttagctac
     9481 tatttttcgt agaccattga atacagtaag aatggctatt ggagtttttg aacagtttgg
     9541 gatgattgag attatcgatg gtattattag cttgccaaat tgggaaaaac atcaaaacgt
     9601 tgacggaatg gagaaaatca aggaacagac acgtaaccgt gtagccaaat accgtaaaaa
     9661 acagaaaaat cttgctcttg gtaacgttac agtaacggac ggtaacgcac tagaagaaga
     9721 taaagataag aatagattag ataaagataa gaataagaaa agaataacta ctactagtag
     9781 tggtagtgaa gaaaatatct tagaactttt tcaatctgag tttcgtagac tcttatctgg
     9841 atttgaaatt gaagaaatca accatctact aaatgagaat gatgtggatt tggtgaaaga
     9901 agcattgaag actgctatta actcaggaaa gccgaacatc aaatatattg gtgggatttt
     9961 aagaaattgg cagatgaaca atgttaccac tgttgaacag gttcgtcaat cggaaaagaa
    10021 gaacaaggat aagaaagaag aacaggaggc caaggacgaa tgggggtact agaactaatt
    10081 gaacaattcg agattgacta ttatccgtta agctacgaga agaaaactct tttagcagac
    10141 caaccaattc atcaagtggt tgcctgcttg tctgaaatgg ctagctggca tgaatgcgga
    10201 ggtcggctag tatggtagac aatgtgtttg aggaaatcgc cttatcttat cgtaggaata
    10261 cagaacaaca agaagagttc tgcgaaaagc ataacatccc tttgataaag atattgagga
    10321 ccgagagtgt tgtatgtcgc atgtgtgaat ctgagcggat tcatgaagaa aatcaggaaa
    10381 gagtgaatga actggctaat gctgagaatg agcgagagag gaaatactat cttgaaaagt
    10441 tctctcttta tgatgaagtt ttgaaaaatg ctactttgga caattttgaa acaccaaccg
    10501 aaaaagaagc ggaaaagcta gcttttgcaa agaggatttg tcgtgagtgg tctgagggtg
    10561 ctaggaacaa catcgtgtta caaggagaag ctggaacagg taagagccat ttggcttttg
    10621 ctgtggttaa ggctctatct gagtacacga aagagattgc tatttttatt aacgtaactg
    10681 actttctgat gaagattaaa gctgatttta gtcaggaaga gtttctggtc aataaaattg
    10741 ctagtgctaa gttcttggtt ttggatgatt taggaatgga aaaagatagc gaatggtcat
    10801 ttactattct ctacaatatc ttgaataagc gttcaaacac aatcattacc acaaatttga
    10861 tttctgccga tattcaaaaa agatatggca gacctttcat gtccagacta atgaagggtg
    10921 tagataaaga ccatttgatg gttttcaatg atttgacaaa caagcgaaag caatattttt
    10981 agaatagggg tggctgatgt ttattttaaa gcatgggaca agagaggata agccgtttct
    11041 aaggtctgca attatcagtg tgactggctt ggatatttcg tgttctgagg agaagaaagc
    11101 catgcggttt atttctcggg cggcagcctt acaggttagc aaggcattga gaggttcctt
    11161 tgggaacttc taccctgtcg aggtggagtg atgttagagc tttacttcgt ctacaacggg
    11221 cactgcaagt tttaccttgg aacgtttgac aatgtcgatg atctcattga acagatggaa
    11281 gatcatcagt gggctttctc ggctatcact catccaagat ttcagaagca cattggtcag
    11341 cggacgacac gatttgacta cggttctaag gattgttact atttagcgac tttttcagga
    11401 ggagaaaaaa atgattgaac ttattaaaga atttggaatg gctattctgt ggttatttct
    11461 cggctattta gtcggggaac gtgcagcaag aaaggaaaag aaagatgatc aataacgtta
    11521 catttttagt gggaggtaag aaacatggtt ggagtaacct atcaggaaat tcatctcttt
    11581 gttgaatttt tgaaagagca gtacgggcaa ggtcgtccag actatattga agccctgaac
    11641 gacttagacg gtctggtgga agtctcctac agagaagcta ttgaaagatt tttagaagat
    11701 gaagtacgat aaacaggctg agattgacgg actgaaacgc acgatcgagc aaaacgaaga
    11761 gaagataatc gagtattcga agccgtgcga tgcacgcaag agacggatta gagcgctgga
    11821 gcgcgatttg ttgaggaaaa agaataaaga attgagacgg aaagtggagg agttggaagg
    11881 taatggaaga gttaaatcaa aaagttaatg cagtatacaa ctggacggta gaagacggga
    11941 agcccaaacc tcccaagcaa gatttaccac aagcggtgaa agaccgggcg gactattttt
    12001 gggaaatggc agaagatggt atgacgttta tgggagcgat ggaatgcatc ttcgctgatg
    12061 aaaagcctac agactatgaa ttgggagcta ctaagggttg gttgccaaaa tctaaggagt
    12121 ttgatgattg ggttggctat tcgccaagca tgactcaggt agttattgca gtttatttga
    12181 tttatggagg aagcgaagat gaaacttaat gaattgatta agaaatataa aaaacttgag
    12241 ggtgtatgga atgctgaagg agcagaacta gctcgtcaaa tttttctgca agacttggaa
    12301 caactagata aacagcaacc agtcaaagtt aagaagtttg tggcggattt tatcgcagaa
    12361 cagaaaaaac tgggtcatac actgtcctac tcaatagacg caagcatgtc tgacatagtt
    12421 gcagaatggt attgggataa ttccgaactc ttcgcactag cttggatttt cggctgcgag
    12481 gtcgaggaag agaagcggta tacagtagtg acgaaagcaa caaaacaacc gctatattat
    12541 aatgctatgg ataagaaact attcttctct atgggcggac tagctacaaa atttactcgc
    12601 aaacaactca aagaagcgga cttcggctgg gtgtttgatt gtccagggat tgagattgag
    12661 gaggtggagt gatgacacaa acacttgaag aaggaatgaa gaatcaaagt aaatgcataa
    12721 aagtcccaag ggaaatcaga ccgtttgata tagggtatcg aatagtgaac aaatacggtc
    12781 aagcgctcgc tttaagaaat ggggcaagta tattcgattt gccttttctg gctgaaaaag
    12841 ctatagaaaa agagtttggg aagaatgatc cagactttga catcggaaag cattctgttg
    12901 aagaggtcgc tattgtcaat ttaagtaaat ttcatagtta ttttgaggag gtggagtgat
    12961 ggaagatgag caaaatattt tagagataca attgatttta ggtaagcaag ttttagaaat
    13021 tgtattggat ttgctaaaag acgattcaaa aacaggggta gttctacctt taaacataaa
    13081 tgaccgtgaa tttacaatta ctgtagaaaa ggaggtcaca gatcgtgact aaggggtgct
    13141 tgtggttatg aaggacgtgt atgacaaggt gaaagtcggg gatgaggtga tgttgtgaaa
    13201 ttcttggatt tattcgcagg aattggcggt tttcgtttag gaatggagtc tgccggccat
    13261 aaatgtattg gcttttgtga aattgacaag tttgctagag aaagctataa agcgatacac
    13321 aatacgaaag gagaaataga attacatgac atcacagcag tatcagatga atctattcga
    13381 ggaatcggaa gtgtggacat tatctgtgga ggatttccgt gccaagcttt ctcaattgca
    13441 ggaaacagac gaggttttga agatacacga ggaactttgt tctttgaaat tgctaggttc
    13501 gcatctattc tcagacctaa atatctattc cttgagaatg ttaaaggatt gctcaatcac
    13561 gaaaatggag ttacattcga gaccattatc tcaaccttgg atgaactggg gtacaacgtg
    13621 gaatggcaag tgcttaacag caagaatttc ggagtccccc aaaatcggga acgagtgttc
    13681 attatcggac attctagaaa aagaggcacc agaagagttt ttcctatcgg aagagcaaat
    13741 agagaatttg attttgaacc aaaaataaag attgttggta acactaaaaa tccgaacggg
    13801 acaagtcaag ggactgggag cgttgtttac gactcaaacg gtttagtcgg tacgctttgc
    13861 gctagagatt ataaagagcc aaaacaagta gctataccag tattgacacc tgatagagta
    13921 aataaacgac agaatggtag acgtttaaaa aaaacggtga gcctatgttt acgctgacgg
    13981 cacaagaccg tcatgggatt ttaattaaag aagcaacaaa aaaaggttat gcagaggcta
    14041 cagttggtga tagtgtaaac ctatctcatc caaactctaa aacaaggcga ggtagagttg
    14101 gtaatcagat agcaaatact ctcttaactg gagagagtca aggtgtggtt gagcctgatt
    14161 ttaggattag gaagctaaca cctaaagaat gctggaggtt acaaggtttt cctgattggg
    14221 cttttgacaa agcgcaagag gtcaactcta acagtcaatt atataaacaa gcaggaaata
    14281 gcgtgacagt taatgtcata gcagcaatag caaaggagtt atcatgaaca caatagagaa
    14341 agtcaaacaa tggtttattg accgtgattt agaaaacggt agggtcgttg gattgatggt
    14401 gctttcgtca aagaggagga tttataaaat gaaaagacta ggaatcatta ttggggcggt
    14461 atttgtaatc gttgtatcgc cgtttgtagt tcagtatgga tggaatgaga ttatcacaac
    14521 aattgttcca gttggtaaaa ttacagtctg gcaagcatta gggatggatg cactactatc
    14581 tttcatctgg cctgtgctat ctagcaaaaa agaatctgaa gaggattatt cgtatgcggt
    14641 aaagagcagt atttcaaaaa tcattacatg tgcatttttg atatggttag ctagtttgtt
    14701 tatttaagga gtgttagcat gataccaaaa tttagagggt tatccattga cgaaaaaagc
    14761 aaaggagaat ggcaatacgg acatttaatt gaagatagag gaagagcatt tattatcaac
    14821 gaagtggtag aagccaatga acaatacatt actataggtt cttggtgtcc tgtaaatcca
    14881 gcaacattag gacaatcaac aggactcaga gacaagaacg gcaaggaggt attcatcggt
    14941 gacatcgtta aatgtacaag aggatgtctc catgaagtat atttagaaaa agaatacggt
    15001 ggcacataca taggtggaat gcctgctgta tacctaaaag gatttggaga tggatatgcg
    15061 tggacggaat atgaggaaat catcggcaat gtctacgaaa atccggagct tttggaggtc
    15121 aacgagtgag atattttaaa atcctatgtt tggtattact gaacaaacag ttagatttta
    15181 tggaacgaag acaagtagga atagatatcc gatctcgaca attttgataa cttgtttaca
    15241 tttttgaaaa acttggaggt ggaaattgaa aaaattgagc gacgaagacc tcaaaacatt
    15301 agacagagaa cttttcaaat ttcaaaacat tcaacgtaca atagatttga gaaggctaga
    15361 attagaaact cgaaacccag atgctcagag tggtcccagc gtaggaataa gcaaacctac
    15421 cgaaactatc gcagtcagaa tcgcagatga tccaacctta aaatttctcg aagggttcaa
    15481 agctattatt aacaaactct tgatcaatct agttgatgaa gataaggaaa tctttaatct
    15541 gcgctggaga tatcctcaac tgagatggga agaaatagca gaacagaaat tcatgagcaa
    15601 agctacaatc tatcgacgta gaaggattat cttagaacag tacgctatac tgaaaggtga
    15661 gttgtaaata agattgagac aaaagacatc ttgaagtctc acaaaaaaag gtctattatg
    15721 atagcatgaa cttctgaaac aaaaacacac atcacacttg aggagtcatc cttaattcta
    15781 gtcaaaaagt tgtccaacag aagtatcgtc aagagtcagc aaatgctggc tttttgtttt
    15841 tggaaaggag gtagaatatg gaatttgtat caccgataaa agataatgac gacattcagg
    15901 caatgaaaga ttatcttaga gagtggaatg agatgtatta tatgctattc attacaggcc
    15961 tgaatactgg tttgcgagtc ggagatatac ttaccttgaa agttaaagat gttcaaggct
    16021 ggcacatcaa actgagagaa cggaagactg gcaagcagat aacaagacgg atgacaaaag
    16081 aactcaagaa agaaatgagg agatatgtcg agggcaaacc atttcatcat ttcttattca
    16141 agagtaggca aggtcagaat aaagcaatca ctcgtgagcg agcctatcaa atcatacatg
    16201 aagcagctga agaacttggc attgataatg ttggcacaca tacaatgcgc aagacattcg
    16261 gctataaata ttacaacaag acaaaggacg tagggacatt acagaaaatg ttcaatcact
    16321 catcacctgc aattaccctg agatacatag ggatagaaca agcagagctc gatgatgctt
    16381 tacggaactt tgtcatttaa tttttttaga tattactttc acataatgag ttaagcataa
    16441 actgaaaaaa tgaaactctt taaaacccat gcttagtaag ggtttgagat ttagagtgag
    16501 tttaacaaaa tataagatat gtgaaagtga gggataaaat tggtatagtt acaagtaccg
    16561 ttaacagcca tactagtaaa atggaataat ttttttaaag aatcagaatg agacaaaaga
    16621 catcttgaag tctcacaaaa aaaggtttat tatggtagca tagatttctt gtatgaggag
    16681 gggataggtc aaaggcctgt cccttttagc attgagaaag gaggtttgag atgtataaca
    16741 aacctatcag accatccttg aaatctaaga agtgggagaa gttccgtgat aggataatgc
    16801 gtaagcatga ttatctttgc caagaaagtt tgcgttacgg aatttctgtt caagcagaaa
    16861 tggtacatca tatctttcct gtgtctgaat atcctgagct tgaatttgtt gaatggaatt
    16921 gcttgccatt gacgaataag aaacataata cgtttcatga tagagtgaac gatagagtaa
    16981 tcaaccaagg attgtattgg cagaaaaaaa gaaaaaaaga atttttaaat tttttcaaaa
    17041 atgaaaaatg aaaattttta atccccccct ctttttgaaa aatcattttg gccagtaggg
    17101 taccggtgaa gggaactttt tccaagtcgg gggccttcaa acaaaaaggg ggtaaaaact
    17161 aagcgatttt gacgaaagga ggtagttttt ggctaaacca attacagcaa agtcgattaa
    17221 gtcaaaagtg gtcaagcaga tgaaagactt gggaacttat cgtaaagagt tcgaaatgat
    17281 cattgacatt tttgcaggta tgttatacca gtatcagaaa cttgctcaag attatgctga
    17341 catgggttat ccagtaacag acacctacgt caataaggct ggtgccgaga atgagcgcaa
    17401 agttccaatc ttgacagcaa tggaaatttt gaggaaagat atactcagct actctaatca
    17461 gttgatgatg aatcctaagt cgctcggtga ggtagtagaa caagagggtg agtcagttct
    17521 tactgaggta ctgaagttca agaacgaaat caagaagaag cgagtgactg gcaatgggta
    17581 atcttgataa agctaaagaa tacgctcaac acgtcttaac tcaccgagaa gaacattgcg
    17641 aagaaaacat ccttgctgct gaacgttttt tccgtgattt agaaaatcca acctttgaga
    17701 tggatgagga tatggtggat tttgttattc actttatcga gaacgtgata gttcatcagc
    17761 agggcgatga tatgtttgcg gtatctatcc gtaacaagcc attgcttttg caaccgtggc
    17821 aacatttcgt tgtagttaat ctatttggtt tttactacaa gggtacgaat gagcgcaggt
    17881 tcaaagaagc gcttatcatg cttgctcgga agaatgggaa gacctcgttt actgctgcaa
    17941 tcgcacttgc ttatcagata ttagatacag atagcggttc caaatgctat atcgttgcta
    18001 actcagtcaa gcaagcgatg gaagcttttg gttttttaag attcaacgtt gaacgctgga
    18061 acgataagaa cattcgtatc aaggataata accaagaaca ctctatcacc gccaattttg
    18121 gtgatgaagg ttctttcttt atccaggctt tagcgaatga tgagagccgt ctggactctt
    18181 tgaacggaaa tgttatcatc ttggacgaag ctcacacaat gaggaacagt aagaaacatg
    18241 gtcttatgaa aaaaacaatg tcagcataca gaaacagtat gctttttgtt atctcaacgg
    18301 ctggggatat tcctaccggg ttccttgcta accgtctgaa atactgtcaa aaggtgctca
    18361 agcaattagt cactgatgat tcatttttca tcttcatctg caaggctaat caatctgctg
    18421 atggggacgt ggtgaactat ctggacgaga atatcctcaa gatggctaat ccgtcatggg
    18481 gtgtcacggt ttcgctcaag gctctcaagg aagaagcaga gcaggctatg aatgatcctc
    18541 agacaagaaa tgagtttttc aataagacct tgaatatctt cactaactct atgaacgctt
    18601 attttaatcc tgatgagttt attgcgtcgg atagttgcta cgattggagt ttagaagagc
    18661 tggcacgttt gcctattcgt tggtatggtg gtgcggactt gtcaagattg cacgacttaa
    18721 cagctgctgc tctctatggt gtctatcatg acggtgagaa agacgttgat atctgtatca
    18781 cacatgcttt cttccctcgg attaatgctc agaaaaaagc taatgatgac gggattccac
    18841 tctttgggtg gcagtctgac ggttggttga cgatgagcaa cactccgacc gtcctctatg
    18901 atgatatcgt caaatggttc atcaagatga gggagaaagg gttcaagatt gctgctgtcg
    18961 gaatggatag gaagtttggc cgtgagttct tgacgaagat gaaacaagct cggttcaaga
    19021 tgattgacca acctcagctt ttttatctga aatcagaggg attcagacgg attgagttta
    19081 aagttaagaa taaagaattt tactatcttc attctgatgc ttacgaatac tgtgtgagca
    19141 atgttagagc aattgaaaag gtggacgatg ctgtgcaata tgagaaatta gatggagacg
    19201 gtgggactgc aaggattgac ttgtttgatg ccagcgtctt tgcttgtata caggctcttg
    19261 ctaatcttgg caagggtggt gatgtgatga gattctttga ttaggtgaat tatgaatgaa
    19321 atagtattat cagaacatga aattaacttg ctgatcaaca aagggcgagt taaagtaatt
    19381 ttaaacgggg aagtagtaac tattcgtcaa agacatatga aaaatttgat ggctgaaaca
    19441 gtaaaatggg aaaaacaggt aattgatgtc agtcagaata tcgtaagaaa taaacacttt
    19501 gattcacttt ttcaaaatac ttttcgttag aaaggaggtg aggaaacatg ggtatttttg
    19561 aaaagttttg gaaacgaaac aagccaagta agtcaatcaa catgctgagt cattcagatt
    19621 tagggttgtc aaaccttatg gattcgtatg tacctttggc cagaaatcca gatgtggtga
    19681 cagcggttaa taagattgct gatttggtct ctaatatgac catccatctg atggaaaaca
    19741 cggataaagg tgatatcaga attcgtgacg gacttgctag aaagattgac attaatccgt
    19801 gtgaacacat gacaaggaag tcatggattt tcaagattgt gcgcgatttg cttttatatg
    19861 gcgatgggaa ctctgtccta catgtggaat atgaacctgt tacggattat atttctaatc
    19921 taagaccatt tccgatgaga gaggtttcat tccaaacaga taaggattcc tatgtaatct
    19981 catttagggg tgaagaatat tcccctgatg aagtagtcca cttcgtcatc aatccagatc
    20041 cagatattct atacattggt actggtttta gggtgacgtt gacagatgtg gttcaaagtt
    20101 tgaacatggc taccaagact aaaaaaagct ttatgaacgg gaagaatatt cctagtctta
    20161 tcgttaaagt agactcgtct agtgctgaac tagattcgga gcaagggcgt gagcgtatcg
    20221 ctgagaagta tttgagtact agcagggttg gcgctccatg gattgttcca gaggcattgc
    20281 tggacattca gcaggtaaaa ccgcttagtc taacggacat cgctttaaac gagtctgtgg
    20341 aattggataa aagaacagtt gcaggtctat taggagtacc tgcttttatt ttgggtgtag
    20401 gagaattcaa caagacagag tataacaact ttgtaaatac gactgtcatg agtattgcta
    20461 ccactattac tcaaacacta accagggact tacttttgtc tagcaatcgt tacttcaagc
    20521 taaatcctcg ttcactcttc tcttacaaca ttacggagtt gtctgctgtt gctcaacaaa
    20581 tggcaaacag tgctgcaatg cgtcgtaatg agtggaggga ttggctaggg atggctcctg
    20641 atcctgagat ggaagagttg attgttcttg aaaactttct ccctcaggag aaactaggag
    20701 atcaaaataa actgaaggga ggtgaggaag agaatgcaaa agcgaaatag ctatcgtgcc
    20761 actcaatttc aaacgagaga agaagaatct ggagacttgg tgttgagtgg ctattttata
    20821 aaatttgatg aagagacgga gttgtggcgt ggttatcatg aagtaatcaa gcgtgctggt
    20881 gttgagaaag ctgtcacaga cgctgatatc agagctttat ttaaccatga tgatagcctt
    20941 gttctcggtc gaacaggtaa cggaactctg acactgggtg ttgatgatgt tggtcttttt
    21001 ggagatatca tcattaacaa ggatgatcct caagctgttg gggcctatgc ccgtgtcaag
    21061 cgtggagatg ttatagggtg tagctttggc tttatcccgg taaaaatcga aacggaagaa
    21121 cgtgaagatg gttcatattt ggacactgtc ttagagctag aaatctttga agtgagtcca
    21181 tgtactttcc cagcctatcc acaaacggaa attgctgcac gacaaaaaga cttcgaaagt
    21241 cagaagcgtg ctaatcgtga agcgctagac aagcgcaaga aagaaattaa ggagaaattt
    21301 aagctatgaa taaggcatta atctttggtg ctcgtatgcg agcaaaagca actaaggtag
    21361 ttgagttgga agaaactatc gaagaattga acaaacgttc ggttgttgag ttagaaaagt
    21421 tggatcgtgc taaaaatgat gaagaagttt tagcagttga aaagactgta gacggtcttc
    21481 aaagggaaat tgaagaaaaa gaagctgaaa aagtacagct tgaaaacgag atcgatgagt
    21541 tagataaaca aatcaaagag caaaatcgta aagcaccaac tccggggaaa atggaagaac
    21601 gaggaggaaa gacattggga caacgtgaag catttaatca ttacttacga acaaaagaag
    21661 cgcgtgctga tggtttcaaa tctgccgaag gggaagcaat cattcctgtt gaattgatga
    21721 cgcctaaaga agcgaaacaa gacaagacag atttgacttc attggtcaac atcgttaatg
    21781 tcaagaacgc aagcggtaaa tggtcagttg taaaattgac tgatcaagaa atgaacactg
    21841 ttgaagagtt ggaagaaaac cctgaattgg ctaaaccaac ctttacaaag gtgaactatg
    21901 aaatccaaac acgtcgtggt catttgccag tatctcaaga atttattgat gacgctgact
    21961 acgatgtcat gggattggtt gctaaacaaa ctaagaacca agaacgtatc actaagaata
    22021 aagagatcgc taaagttctc aagacagcta catctaaaag cgcagctggt ttggacggct
    22081 tgaaagatat tctcaacgtg gaattgaaaa catactacaa tgcaactatc gtatgtactc
    22141 aatctatgtt cgctgctctt gataaaatca aggacaagga cggtcgctac atgctccaaa
    22201 cagatatcac atctccaact ggctacaagt ttgctggtcg tgttattgtt gtttatccag
    22261 atgatatcat tggagaaagc aagggagatt tgaaagcctt catcggtgac gttggagaat
    22321 ttgcgacatt gtttgaccgt gcgcagacta ctgtcaaatg gcaagatgac aaaatctacg
    22381 gtcagtattt ggcaaccgct aatcgttttg atgtagtaaa agtagacgga gatgcaggat
    22441 tttatgtgac ctatacagat gctgttttgt aaggaggtag taaatggtat ataaggtaat
    22501 ccgtcctttt aaggacttac gagacccaaa gaaacattgc tataaggttg gggataatta
    22561 ccctagagtt aagcacaaac ttgataaaga gtttgcggag actctgctaa atggggcaaa
    22621 tagtgcagga tctatctttt tgatgaatgt agaagataag gatatgtcga aagatgacac
    22681 attaactaca gaagtagaaa aggaagaaac aaaggtagta gatgggaaac ctgaagaggg
    22741 agacgaggag tagttatgga caatgttcaa ttattagaat tgcttaagct aaaattgggt
    22801 atagcaacaa aactacgcga taagcccttg gagaaaatca tcgaagctgt caaaacagaa
    22861 ctagaagata acttaggagt tctacttgac ttagacagct cagaagacca aatgtttgta
    22921 gttgattttg cagcctttcg ctatgagggt ggggtggata tgccacgtca ccttcagtgg
    22981 cgactgcata atttacagat agcatcaaag aaagaggtca agaatgtgga atcatgaaat
    23041 cacactgatc tctaaggaag tcacaggtaa ggataaacta ctacaaccaa tctctgaaga
    23101 tgttgaagtt actctcctat gtcgcaaaaa gagggtcact cgctctgaat tttatcaggc
    23161 gaatcaggta gggcttaaac cgagcttggt cgttgagatt cgaaattttg agtatgagaa
    23221 tcaagagctt gcgaagttcg aaggcaagca atatcatatc ttgaaaacct atcctattga
    23281 ttctgaaatt ttagagttga ctttgtcaga ggtgttgaaa tgagcttaac aagtgattta
    23341 gcgaatgaaa ttgcaaaggc aatggcagag tactctgctg aggtagaaga taagattgac
    23401 ctgattgctg aggacgttgt aaacgaagcc gttacggaat taaaagcgac tagtccaaaa
    23461 cgtcatggaa agtatgctag aaattggcgc ttcaagaaaa atgctaaggg gtcatacgtc
    23521 atctacaacg cagctccaac ctatcgttta actcacttac tagaaaatgg gcatgttttg
    23581 agaaatggcg gtcgtagtcg ggcatttcca catattaaac ctgttgagga gaaagttaaa
    23641 gaaaactttg agaagcgaat caaggagatt gggaaatgaa gctatcagac tttgctgcta
    23701 ttttggaaca ggcaaacttg cctgtcactt atcgagcgtt taaaattgga aacgctcctg
    23761 acctacctta cctggtctat tatgaatcaa gtccagtcat caattcagct gacaacacgg
    23821 ttaatcatca gattaagagc gtgacagttg agctggtttt tgagagtaag gatgaagatt
    23881 tggaagaacg tctggaagag ctgtgggcaa accacaagct cttttttgaa gttcaagaag
    23941 aaacatttat cgagactgaa agactctatg tcaagtctta cacagtctat ctatactaag
    24001 gaggaatgac atgactcaag aaaataaagt aacctttggc ctagaaaatg tacatatcgc
    24061 acctatcaag acacttgcag cagatggagt tatcacttac ggcgatgttt ttcgttttcc
    24121 tggagcaata gatctgacac ttgatactaa aggggaaaca accactatca aagcagacaa
    24181 caaggattac catttcatga attcaaacga aggatatgag ggtaaactta aaatcccaca
    24241 catcattgat gaatttgcga caaaaattct tggtgaaatc aaggaccctc aaactggtgt
    24301 tatgactgaa aaagcagatg cgagcttgac agagttcgca atgatgttcc agtttgaagg
    24361 cgacaaaaac aagactcgct atgtgatgta ctactgtttt gccagtcgcc catctcttgg
    24421 ctcaaaaact aagaacggga catcaaccaa cgaacgtgaa cttagtttca aagctagccc
    24481 gcgtccattg gatacagttg tcaagcgttc tatcacatca gctgatgaca aggatgcgta
    24541 tgacaactgg ttcaagaaag tgtatgaacc tactgcagtt gcagcttaag gagaagatct
    24601 atgcgtaaaa tcgttttggt tggtgatcag gagtatgagt tggggaccaa cggctatact
    24661 cctattgctt acaagcaaca atttggaaaa gattattttc aagatttgtt ctcgatgttg
    24721 aaaaatcaat cattcatgaa tgaattgaac aagttggaaa ccgacaagga attgacagcg
    24781 actaatattg atatttcgat gttgtcagat tttgacatga cctttttcaa ccgtcttttt
    24841 tggacctttg ctaaatctgc aaatcctcac atcaagcctt atgaacaatt cttcatggaa
    24901 atggaagtct ttccgattca ggaagttggg cctgtattga tggaaatgct gaatgcgagc
    24961 atgacgacaa aaaagcacca gatgaatcag aatcagctag cgaagaaatc ttcacagtag
    25021 aaacctactt atcttgctgt aaagaaactg gtctttctat tgatgatcta aagcacattt
    25081 caatcggaat ggctctggat tatcagacgg attatgtgaa tctacggagc gaggataagg
    25141 gtggcgaacg gaaagccacg caagctgatt ttgacggttt ttaaagaaaa atgagtgctg
    25201 agagagcgat tctgagacca agttccttgg tctggctgca ttatcagtgg tagaagttct
    25261 ctcagcgctt ttctattttt ttgagaaagg aggaaatatg gcaggaaata tcaaaggtat
    25321 taaaattgaa atcgatggcg acacgcaacc cttacagaag gcgctgaaaa atgtcaataa
    25381 ggctgctact gatgcaagtc aggagttgag acagattgac aaagcattga agtttgatac
    25441 agggaacgta acgctcctga ctcagaagca agaggtcttg caaaagcaag tttcgacgac
    25501 caaagagaaa ctagaaacct tgagacaagc tcagtctcag gtggaacagc aattcaaaaa
    25561 tggcgatatc ggtgctgacc agtaccgtgc tttccaacgt gaagtagaag ttactcaaaa
    25621 cgtcctaaaa ggatatgagg gtaagcttgc aaatgtgaat caggcgctta atgagaatgg
    25681 gagtgctact cagaacaaca agaaccaatt aaaagagttg caaaatgagc agagtcaact
    25741 tgcttcagag atgagtaagg tgacaagttc attcaaactg caagaaagcg ctttgggttc
    25801 aaatgctagt gaagccgaga gaaatgctct tgctcagaaa aagattggtg ctcagtctga
    25861 gattgtaagt aaacagattt caaatctaga acagcaattg gaaatcacta aaaaagaatt
    25921 tggtgagaac tccacacaag ccaacaggat ggaagcagag ctaaatcagg ctaagacagc
    25981 attcaatcat ctcaatgatg agatgaaagg aacaaagtct gctgctgata gcactcaaga
    26041 aagtttaagt gaaatctcaa gaaatttaag agcagaacta cttcaacagt ttagtgagaa
    26101 gttgagtgct atttcagaaa agcttgtgga agtaggaaaa gaagcgttag aagcagctgc
    26161 tcaaatgcaa gctagtaatg ctcaatttac taccgttttc ggagatatgg aaacccaagc
    26221 aagagaagcg ttgaatgcta ttggtcagga aatggatatt gtcccagagc gattgcaagg
    26281 atcattcact cagatggctt catttgcaaa aacttcagga ttggatacag cagaagcttt
    26341 ggatcttact tctcgtgcaa ctagggcagc agcagacggt gcagccttct atgacaaatc
    26401 tattgagagc gtgacagaga gcttacaatc ttttttgaag ggaaactttg ctaacgatgc
    26461 ggctcttggc atttctgcaa cagaaacgac caggaatgcc gctgcaaata aattgtacgg
    26521 aaagtcattc aaggacttga gcgaagcgca gaagcaattg accttgcttc agatggtcga
    26581 agacggaaat aaactctcag gagctcttgg acaggctgca agagaatcag acggcctgga
    26641 aaacgtgatg gggaatctga aacaagctgg gaccaatgca ttatctgcta ttggtcaacc
    26701 tcttctagaa atgatgattc ctgtttttca aaccttggca acgattgtga aaggtgtagc
    26761 tgagctgttc agttccttac ctgctccagt aaaagatttt gttgttattt taggaacagt
    26821 tgtgactgct gtaggggtca tagcccccat attcttatcg ttgcaagccc ttgctgagtt
    26881 tttaaaaata tctattggag aaatgataat tgccgcattg ccaattattg gaacagctat
    26941 tgcaattgct gctgcagttg ctgcaattat tgttattgta aaatatctct gggaaactaa
    27001 cgaaggtttt cgagatgcgg tcacgaccgt ttggaatgcg attcttgaag ttatcaatgc
    27061 agtcgtatca gagatttcta attttgtcat gagtatcttt ggaacggttg ttgcttggtg
    27121 gacggagaac caggaactta ttcgagcaag tgctgagact gtctggaatg ctatctatac
    27181 ggttataagc acaattctgg aaattttagg tccactcatt caagctggtt gggataatat
    27241 ccaacttgtc attacaacag cttgggaaat cattaagact gttgttgaga ctgcaataaa
    27301 cgttgtcctt ggtatcattc aagcagttat gcagatcatc aatggtgatt ggtcaggcgc
    27361 ttgggaaact attaaggggg tattctctac tgtatggcaa gctatccaaa gcattgtaca
    27421 gaccattttt tcagctatcc agagttatat ttcaaatatt ctcaacggca tttcaggaac
    27481 tgtatcaaat atctggaaca gcatcaagga cactgtctca aatgtgttaa atgctatatc
    27541 tagtactgta tcaagtgttt gggaaggtat caagagtacc atttcaagtg ctatcaatgg
    27601 tgcaagggat gctgtttctt cagctattga agccatcaaa ggcttgttta acttcaacat
    27661 cagctggcca catatcccac tacctcactt ttacgtgagt ggttcggcca atccattaga
    27721 ttggttgagt caaggtgttc caagtattgg aatcgaatgg tatgccaaag gcggtatcat
    27781 gacgaaacca actatctttg gaatgaatgg taataacata atggttggtg gtgaagctgg
    27841 gaatgaagca gtattgccac ttaacgacaa aacgcttgga gccatcggtc gaggtatcgc
    27901 tcaaactatg ggtggaactt caccaaccat caacattact attactggta acaccgtcag
    27961 agaagaagct gacatcagtc ggattgctga tgaggtggct cagcgtattg ctgacgaatt
    28021 acaacgtagg agacaattga gaggagggtt tgcatgataa agcataatga gcttgtgatt
    28081 gacggtgtga ggacatcgtc ttttccattt aagatcattg tccatgactc tccttcaatc
    28141 gctctaggag agagcaagac agctctcttg gaacatggtg gtgtcagtgg ggcaattgtt
    28201 cagacgaaca agcacaggga actggtcaag aaatcttata cgatttactt agtcaaaccg
    28261 actgaggagc agatgaacca atttatgagt ctgtttatcc gtgagaagtt ctggttagag
    28321 agcgagcgag tcaaaacaac tcgtctctgg tgctataagg tcaatgtgac tgaccttgaa
    28381 gaagtacaac ctggtcttta catgaccaaa gcgaccttca cttgccatcc tacaaaatac
    28441 ttcaaagcaa ctgatactca gagattgaca agaagcggga ctctgaatgt gcaaggttct
    28501 gctcttgctt ttcctaaaat cacaatcgtt ggtcagagcg ttgttgagac ttcatttaca
    28561 atcgctggtc aggttattag gcttgaaaaa ctctcagaat cgcttgtgat ggttaataat
    28621 cctgacaatc ctagctttaa aacgacaaca gggaagccag tgaaatggtc aggggatttt
    28681 atcacagttg atccagcgaa agttaagaat attggggttg ttttaggccc aggtattcaa
    28741 tcgattgaaa tcgaaacggt ttgggggtgg gcataattgc tttatctact taataaagat
    28801 gtaagaaccg ttcgatggaa cggggagcca cttcatgaag cgacttcggc gattgtgaaa
    28861 gaaactatga atggcgattt taccttgact gtgaaatatc ctatttctga ttctggtatt
    28921 taccagctca tccaagaaga tatgctgata aaggctccga ctcctgtctt aggtgcgcag
    28981 ctatttcgca ttaagaaacc tgttgagaac aatgaccatc tggaaattac agcctatcac
    29041 atttcagatg atgtgatgca acgttctata acaccagtaa gtgtgactag tcagagctgt
    29101 ggcatggctc tttctcgcat ggttcaaaac accaaaaccg ctttgggaga tttttctttc
    29161 aatagcgata tccaggaccg taggaccttc aatacgactg aaatagaaac tctgtactct
    29221 gtattgctgg acggtaagca cagcattgtt ggtacatggg aaggcgagct ggttcgtgat
    29281 aactttgcga tgactgtaaa gaagagtcgt ggtgagaatc gtggtgttgt tattacaaca
    29341 cataagaatc tgaaggacta ccaacgaacc aaaaacagtc aaaatgttgt tacaaggatt
    29401 catgctcgat ccacatttaa gcctgaaggt gctgaaaagg aaacaactat cagagtgact
    29461 gttgatagtc ctcttattaa ttcttatcct tacataaacg aaaaagagta tgagaacaac
    29521 aacgcaaaat ccgttgaaga gttgcagaag tgggcacagg ctaagttctc aaatgagggc
    29581 attgacaaga tctctgacgc tatcaagatt gaagcttatg aacttgatgg gcaagttgtt
    29641 cacatgggtg atacggtcaa tctcaagagc tggaaacata atgttgatgt atttaagaaa
    29701 gctattgctt atgagttcga tgccttaaaa gaagaatata tctctctgat tctcgatgat
    29761 aaggcaggag ctggtggttc tagaacatct ggtggcttat ctagcgcagc gtatgccatt
    29821 cttggagtaa cagaatctgc acaagaagtt gcccttgaaa aggctcttca aaatgctgac
    29881 ttagactttg atcataaggc tggattgctt agacaggaaa tttctgacgg catcgaactt
    29941 gccaaggcca aggcggaaga agtcaagcaa gaactgtctg acactatcaa tcagcgcttt
    30001 aatagctttg acaacgggcc attgaaagaa gctaagcgca aggctgagga agctttgcga
    30061 aatgctggcg caagtagttc tcttgctcag gaatccaagc ggattgggct ggattctgtt
    30121 gctagacttg aagcgtttaa gtcgcagact acgagcgcac aaacggctct gtcaggtgac
    30181 ttggacgctc tgaaacggac tatcgtgaat gatattcgac cgaagcaagc acaggttgaa
    30241 gctgagattg ccaagcaagt tgaagcactt gttcagacca aaaaagaact gtctggcgca
    30301 agtaccctgc ttgcacagga agctaagcgg attgagctgg attctgttgc tagacttgaa
    30361 gcgtttaagt cgcagactac gagcgctcag acggctttgt caggtgactt ggatgttcta
    30421 aaacgaacta tcgcaaacga tattcgaccg aagcaagcac aggctgaagc tgagattgcc
    30481 aagcaagttg aagtacttag tcggactaag aatgaactgg ctggcgtgaa gtcagcgcaa
    30541 gcgacgtatg aggagacgac gactcgtaga ctgtcagaac tgaccaactt gtccaatggt
    30601 aaagccagca agtcagaact cacgcaaaca gctgaggagc tggctagtcg gattgcgagt
    30661 gtgcaggcag gtagttcacg gaattacttc aggaattcac gttcaagaac gttcacaaca
    30721 ggaggtcaag cggtatacga ctatcgaaca ttcatagttc ctgatttctg gaagaacagt
    30781 gacaggttca agcgtgatta tgttcgcata tcttttgatg tgactttccc tgtcgcccta
    30841 gtaaatgaca tgcctgctat ggtgcatttt agtgctcatc catggtatgc ctacagaaac
    30901 ttaattttta aaggtggaac tgtcgaacgc caacattttg agtttacgat tgacttgtct
    30961 agttcttctg aggactatca gactaataat gtgttcattc gttttggtac taattatgga
    31021 tttcctgctg gtctgcaggt cgtcattgag aacgctatgt tatcggttgg taattatttt
    31081 ccagcctatc aaccagcgta tgaagaccaa gaagaccgtg tctcagtagt cgaatccaac
    31141 tttaagcagc gtgctgattc acttgacgct ggtgtaagcc gtctgactga aggccttaga
    31201 accaaagccg atatcagcgc actcaatgtg actgctgaaa atatccggca atctgtgaag
    31261 agtcttgaga cagacacgca gaacaaacta aatcagaagt tgagtcaggc tgaatttgag
    31321 gtgcgagctg gctctatccg tcaggaaatc ctgaacgcaa ccaaggataa agccagcaag
    31381 tcagaactca cgcaaacagc tgaggagctg gctagtaaga tagcgagtgt gcacttaggg
    31441 cgcagaaatt tgctgaaagg cacaaaagag cttgcgagat acaagccggt tagtgaatat
    31501 aatggtttta aagttatcag aacagtcgca ggagcaacta gatatcagga tagctatgtg
    31561 gaaagaaccg ttataccaac ggctgggaca gagtatatag ctatctttta tgcacgagcc
    31621 agtgaaaatg actatcctgt gcgctgtcat ttttacaatc ctaacacggt tgtatcatca
    31681 gaaaacagca gcggatataa gtcaaggtcg tcagatggct tgtctattat ccgtctctcg
    31741 acagactggc agttgtgctg ggttaaatgg acccaaaccg caacagatca agccaagacg
    31801 gtcatcattg gccgccatgg ccctcaagta ggcggtaaag agggggtatg ggttgaaatc
    31861 tgcgcccctg ccatttttga gggaaatctt gcaggtgact ggtcaccagc atacgaagac
    31921 caagacgaac gtgtctcagc ggtcgaatcc aactttaaac agcgtgctga ttcactcgaa
    31981 gctggtgtaa gccgtctgac tgaaggcctt agaaccaaag ccgatatcag ctcactcaac
    32041 gtaactgctg agaatatccg gcaatctgtg aagagtcttg agacagacac gcagaacaag
    32101 ctaaatcaga agttgagtca ggctgaattt gaggtgcgag ccggctctat ccgtcaggaa
    32161 atcctgaacg caaccaagga taaagccagc aagtcagaac tcacgcagac agctgaggag
    32221 ctctctagta agatagcgag tgtgcaggtc gggggtagga attatatccg gggtacaaag
    32281 cgcatgatgc tagccagagg attgtgggca tcaggtactt ttagaccgtc aggcgctggg
    32341 acggcaaaga cgattgatgt atcagacagt ccagcaactg gctttgataa agcgatacga
    32401 ttgacctcaa gcaatgctag agaccaaata ggtattgctc aagatggatt ttatatctcg
    32461 caaggcacat acacgatgtc ttgttgggtc aaaggcagaa gaggtcaaaa ggtcaagcta
    32521 caaacttatt ggcaagtcaa tgataattcg ggtatttcgc ccatctttac attaaaggat
    32581 gaaaattgga caaagctatc gtttactagc gctagaaata gggctggagt cgcatcaatt
    32641 ggctatgtgt atctcgtaaa tgctgaggtc ggagaatatt tagatgttct tgcgccccag
    32701 ctggaagacg gaagtttggc aacaagctca aaagaagctc ctgaagatat agaaggtcag
    32761 atttcaacag ttgaatcgac cttcaaacag cgtgctgatt cactcgccgc tggtgtgaat
    32821 cgtctgactg aaggccttag aactaaagcc gatatcagcg cactcaacgt gactgctgaa
    32881 aatattaggc agtcggtgaa gagtcttgag acagacacgc agaacaaact aaatcagaag
    32941 ttgagtcagg ctgaatttga ggtgcgagct ggctctatac gtcaggaaat cctgaacgca
    33001 accaaggata aagccagcaa gtcagaactc acgcagacag ctgaggagct ggctagtcgg
    33061 attgcgagtg tgcaggcatc cggtcgaaat ctattcttga actcactatt caagcaggat
    33121 attccaaaaa caggaatttg gacaacgagt acatatacgg ctactatcga tagcgaaagt
    33181 aagtatcttg gacacaaggc tcttaaaatt ataggtttga atccatctgg ccgtgatgga
    33241 ggtaatccca aggttactta tccagctctg ggtcaattcg ggaaagtaat tcccggaagt
    33301 acgactaatc aagatgtaac cattagtttt tatgctaagg caaataaaaa tggaataatg
    33361 ctaagatctc gattagggaa tatcggatat aaaactggaa atgtgacatt gtcgacagaa
    33421 attaagcgat atgttgtcca tattccaaaa ggttggacaa acgaatccaa gcagaccaca
    33481 aatgaatggt tgttcaattt caaccaggaa ggaaccattt ggatttggat gccgaagttt
    33541 gaaataagcg atgtagatac ttcttattca gaagctcctg aagatataga aggtcagatt
    33601 tcaacagttg aatccaactt taaacagcgt gctgattcac tcgaagctgg tgtaagccgt
    33661 ctgactgaag ggcttagaac taaagccgat atcagcgcac tcaacgtgac tgctgagaat
    33721 attaggcaat ctgtgaagag tcttgagaca gacacgcaga acaaactaaa tcagaagttg
    33781 agtcaggctg aatttgaggt gcgagctggc tctattcgtc aggaaatcct gaacgtaacc
    33841 aaggataaag ccagcaagtc agaacttacg cagacagctg aggagctctc tagtaagata
    33901 gcgagtgtgc aggtcggagg aatcaacctc ttgcgtaata ctgcgagttt gttgattggc
    33961 gatcgttcaa aaggatgttg gatgagtgca agcggaggaa atgggcgagc gattagcgta
    34021 gaagttttgg atcctcccaa aaaaatgata aaaaacatga ttcgtgttat tgaaaatacg
    34081 aatggtggaa ataaagattt aactcaactt gttagattgc gaattggtga aaagtacacg
    34141 atttcttgtt atgcaaggat tgctagcgat agcccaaatg caaacgtgaa cttgctattt
    34201 cgttcgtggg caaataatac cgatttaaat cgcaaatttc agaaatccat ctctcataaa
    34261 aattggcaaa aatattcatt tacatttact gctgatgcaa ttgaaaattc aattcaattt
    34321 ggacaatctg gcgcaggaat tatcgaaata tgcgctccga aaatcgaatc aggaacgtta
    34381 gcgactgatt acagcgaagc tcctgaagat atagaaggtc agatttcaac agttgaatcg
    34441 accttcaaac aacgagccaa ctcactcgac gctggtgtaa gccgtctgac tgaaggcctt
    34501 agaactaaag tggatatcag cgcactcaac gtgactgctg aaaatattag gcagtcggtg
    34561 aagagtcttg agacagacac gcagaacaaa ctaaatcaga agttgagtca ggctgaattt
    34621 gaggtgcgag ctggctctat ccgtcaggaa atcctgaacg caaccaagga taaagcagat
    34681 aagactttag ttgtatctga agctgggaaa ttgcgtgaag aattttcaaa aatgaaggtg
    34741 ggagg
//
LOCUS       DAVLDI010000019        33574 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLDI010000019 DAVLDI010000000
VERSION     DAVLDI010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33574
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.019"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(267..629)
                     /locus_tag="VXD01_000924"
     CDS             complement(267..629)
                     /locus_tag="VXD01_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV0601352.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            643..717
                     /locus_tag="VXD01_000925"
                     /pseudo
     CDS             643..717
                     /locus_tag="VXD01_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(965..1102)
                     /locus_tag="VXD01_000926"
                     /pseudo
     CDS             complement(965..1102)
                     /locus_tag="VXD01_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1480..2169)
                     /gene="rplA"
                     /locus_tag="VXD01_000927"
     CDS             complement(1480..2169)
                     /gene="rplA"
                     /locus_tag="VXD01_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV0601353.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2377..2802)
                     /gene="rplK"
                     /locus_tag="VXD01_000928"
     CDS             complement(2377..2802)
                     /gene="rplK"
                     /locus_tag="VXD01_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV0601354.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFITKTPPAAVLLKKAAGVEKGSGTPNKTKVASVTR
                     AQVQEIAETKMPDLNAANLESAMRMIEGTARSMGFTVVD"
     gene            complement(2925..3641)
                     /locus_tag="VXD01_000929"
     CDS             complement(2925..3641)
                     /locus_tag="VXD01_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV0601355.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3659..4120)
                     /locus_tag="VXD01_000930"
     CDS             complement(3659..4120)
                     /locus_tag="VXD01_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0601356.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDHQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(4122..5159)
                     /locus_tag="VXD01_000931"
     CDS             complement(4122..5159)
                     /locus_tag="VXD01_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV0601357.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQKNEEHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVTSTGKTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDEKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIDLPMTTHFAFSVFEE
                     VGHGANSNIPEEVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSEAVS"
     gene            complement(5257..6582)
                     /gene="brnQ"
                     /locus_tag="VXD01_000932"
     CDS             complement(5257..6582)
                     /gene="brnQ"
                     /locus_tag="VXD01_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV0601358.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6754..6846)
                     /locus_tag="VXD01_000933"
     CDS             complement(6754..6846)
                     /locus_tag="VXD01_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0601359.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(6889..7041)
                     /locus_tag="VXD01_000934"
     CDS             complement(6889..7041)
                     /locus_tag="VXD01_000934"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV0601360.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(7201..7779)
                     /locus_tag="VXD01_000935"
     CDS             complement(7201..7779)
                     /locus_tag="VXD01_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV0601361.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7833..9233)
                     /gene="pepV"
                     /locus_tag="VXD01_000936"
     CDS             complement(7833..9233)
                     /gene="pepV"
                     /locus_tag="VXD01_000936"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV0601362.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLTDLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9246..9851)
                     /locus_tag="VXD01_000937"
     CDS             complement(9246..9851)
                     /locus_tag="VXD01_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV0601363.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            10022..10822
                     /locus_tag="VXD01_000938"
     CDS             10022..10822
                     /locus_tag="VXD01_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0601364.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11004..11837)
                     /locus_tag="VXD01_000939"
     CDS             complement(11004..11837)
                     /locus_tag="VXD01_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0601365.1"
                     /translation="MNHKIAILSDIHGNVTALEAVIADAKNQGVSEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNILFRKV
                     AYDYEAELEFAKSKGLPFIEMYEELRREDNYQRHNLELLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(11827..13671)
                     /gene="uvrC"
                     /locus_tag="VXD01_000940"
     CDS             complement(11827..13671)
                     /gene="uvrC"
                     /locus_tag="VXD01_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV0601366.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNKP"
     gene            complement(13711..14412)
                     /locus_tag="VXD01_000941"
     CDS             complement(13711..14412)
                     /locus_tag="VXD01_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV0601367.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQVSARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14491..15723)
                     /gene="murN"
                     /locus_tag="VXD01_000942"
     CDS             complement(14491..15723)
                     /gene="murN"
                     /locus_tag="VXD01_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV0601368.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15728..16948)
                     /gene="murM"
                     /locus_tag="VXD01_000943"
     CDS             complement(15728..16948)
                     /gene="murM"
                     /locus_tag="VXD01_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV0601369.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17060..17839)
                     /locus_tag="VXD01_000944"
     CDS             complement(17060..17839)
                     /locus_tag="VXD01_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV0601370.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQDFSPESQNLG
                     TPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17908..19569)
                     /locus_tag="VXD01_000945"
     CDS             complement(17908..19569)
                     /locus_tag="VXD01_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0601371.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19744..21966)
                     /gene="recJ"
                     /locus_tag="VXD01_000946"
     CDS             complement(19744..21966)
                     /gene="recJ"
                     /locus_tag="VXD01_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV0601372.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIGANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYRFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22243..23001
                     /locus_tag="VXD01_000947"
     CDS             22243..23001
                     /locus_tag="VXD01_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0601373.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYTHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDMTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            23012..23805
                     /locus_tag="VXD01_000948"
                     /pseudo
     CDS             23012..23805
                     /locus_tag="VXD01_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            23818..24495
                     /locus_tag="VXD01_000949"
     CDS             23818..24495
                     /locus_tag="VXD01_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0601374.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQV
                     NKKAYSL"
     gene            24505..25164
                     /locus_tag="VXD01_000950"
     CDS             24505..25164
                     /locus_tag="VXD01_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0601375.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISNLSHMLAKRWQQAA
                     E"
     gene            25308..26498
                     /locus_tag="VXD01_000951"
     CDS             25308..26498
                     /locus_tag="VXD01_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV0601376.1"
                     /translation="MKSIKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26819..27700)
                     /locus_tag="VXD01_000952"
     CDS             complement(26819..27700)
                     /locus_tag="VXD01_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV0601377.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27841..29169)
                     /gene="vncS"
                     /locus_tag="VXD01_000953"
     CDS             complement(27841..29169)
                     /gene="vncS"
                     /locus_tag="VXD01_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV0601378.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTKNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29166..29822)
                     /gene="vncR"
                     /locus_tag="VXD01_000954"
     CDS             complement(29166..29822)
                     /gene="vncR"
                     /locus_tag="VXD01_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV0601379.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCIFTVRNVGYKLERK
                     "
     gene            complement(29871..29954)
                     /gene="pep27"
                     /locus_tag="VXD01_000955"
     CDS             complement(29871..29954)
                     /gene="pep27"
                     /locus_tag="VXD01_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV0601380.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(30134..31513)
                     /gene="vex3"
                     /locus_tag="VXD01_000956"
     CDS             complement(30134..31513)
                     /gene="vex3"
                     /locus_tag="VXD01_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV0601381.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31565..32212)
                     /gene="vex2"
                     /locus_tag="VXD01_000957"
     CDS             complement(31565..32212)
                     /gene="vex2"
                     /locus_tag="VXD01_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV0601382.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32225..33502)
                     /locus_tag="VXD01_000958"
     CDS             complement(32225..33502)
                     /locus_tag="VXD01_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0601383.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9544 a         7643 c         6237 g        10150 t
ORIGIN      
        1 tttagcaatt gtttcgtact attttagatt cagtctacta tacataaact aacctcctca
       61 ttattagcaa ggattctact gattataacc taattcttag actacttcaa gactaactgt
      121 ccaataataa tctacagata aatcatccac tcttaataaa attttattca atccatctac
      181 tcattcccaa aaggttgctg tataatgcaa gacatttttc ttactgattt tacttttcct
      241 taccctcaat ttagtgagct aataaattat tcttcttcaa aaggttgaga tttatctagt
      301 aactctaaaa cattaatggt aggtagcaac attgcttcac tgctatcaat tgccgaaact
      361 attgaaacaa tagaacgtaa ataatgataa agaatagcag taccatttac gtatagaata
      421 tcggtgatat tttcatctat atttatttca aaatatccta ttacagttac agatattttt
      481 ttcatggcat ctttgtcaac taaagaaaca ctaagtttta cggctccatg actataatca
      541 tctgtatgac caaccttaac tatgggatat aatatatcga aggtaaatgt gaacaaactg
      601 attaggaaat ttaaaccaac ttctaacaat gtgttatact caatgaaaac caaagagcaa
      661 actaggaaac tagcctcagg ttgctcaaaa cactgttttg aggttgtaga tggaactgac
      721 gtagtcagct caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat
      781 acgcacggca aggcgacgtt gacgtggttt gaagagattt tcgaagagta ttagaaagct
      841 cgatggacta tttcagattc attccactag atttcgaaat cgagtagggg ataatctcta
      901 gcccctctca caccaccgta cgtgccgttc ggcatacggc ggttcaacta actgttaacg
      961 catgtcattc aaggtaataa tccaaacacg aaaccaatcc acgtttttca aggactggtt
     1021 ttgatatagc acgtttaagt accgacttct gagatactaa ttgatagtgg tcgccccagc
     1081 cagatacctt atccgctata taggccttat tatcacgttc ctgttcgtag agccacgatt
     1141 tcgctatccc ttcctctgac gattcttatt tccagcgtca gacttaaaac ggtctatccc
     1201 cagaccgttt taatccgcta cctcacgata gtcagacttg ggaatcgcta ttgggttcac
     1261 cggtagtagg tgcccaccga ggacttacac ctcaaatata taataaaatg aaataagaat
     1321 aggacgaatc gttcaggaca gtcaaatcaa tttctaacaa tgttttagaa gtagatgtgt
     1381 actattctag tttcaatcta ctatacaaca tgcccgtcgt acatcaaaaa aagttgagac
     1441 atagcgtctt caactttttt acattacttt aactactgat taaagtgagt ttacgtcaac
     1501 tttgatacca acaccttgag tagttgtgat agtcaagttt gttacgtaag ttcctttagc
     1561 tgtagctggt tttgcttttt ggattgtttc gttgaaagct ttaaagtttt caaccaattt
     1621 ttcagcttca aatgatactt taccgatgat tgcttgaacg ttacctgcac ggtcagcacg
     1681 gtaagtgatt ttaccacctt tagactcttc aactgcttta gcaacatcca ttgttacagt
     1741 accagtttta gggtttggca tcaagttacg tggtccaagg acacgtccaa gacgtccaac
     1801 aagagccatc atatcaggtg tagcgataac tacgtcgaag tccaaccaac cgtcgttgat
     1861 tttagcaaca aggtcatctt caccaacaaa gtctgcacca gcagcttttg cttcttcagc
     1921 ttttgcacca cgtgcgaaaa caagaacacg tgaagtttta ccagtaccgt ttggcaatac
     1981 cattgctcca cggatttgtt ggtcagcttt tttaacgtcg atgttcaagt tgtaagcaac
     2041 ttctacagtt gcgtcaaatt ttgcaaagtt agtttctttt gcaagtgcta cagcttcttc
     2101 tacactgtat gcttttgtgc tgtcgatttt ctcaagagca gcacgaagtt gtttgctttt
     2161 tttagccatt ttctattctc cttgtaagtg gttcaatcga ttttcatctc ccacgtcact
     2221 tctcgaaatg atgaagtctt gcgggttttc agtctactat ttttctcttc ctacggcctt
     2281 aagctccctt gctgtaccca agtacaaggc tcagtcactt gcctagtatg aaaagcaact
     2341 aatagactgc tgtgagattt tctactgtgt tattgattag tcaacaacag tgaatcccat
     2401 agaacgagca gtaccttcga tcatacgcat tgcagactca aggtttgcag cgttcaaatc
     2461 tggcatctta gtttctgcaa tttcttgtac ttgcgcacga gtaactgaag caactttagt
     2521 tttgttaggt gtacctgatc ctttttcaac acctgcagct tttttcaaaa gaacagcagc
     2581 tggtggtgtc ttagtgatga aagtaaatga tttatcttcg taaactgaga taacaactgg
     2641 aatgatcata ccagcttgat cagctgtacg agcgttgaac tcttttgtga atcccatgat
     2701 gttgatacca gcttgaccaa gagcaggtcc aaccggtgga gctggtgtag ctttaccagc
     2761 agggatttgc aattttacaa gtttttcgac ttttttagcc atttctaaat cctcctttgt
     2821 ggttttggcg gtaatgtaag atttttacct cccacaagta tgctttacac atacctttcc
     2881 attatacact atttatctaa aaatgcaaga gaaaactttc atttttaatc gacataatcg
     2941 ccgccttcaa agccatagta ctcttccaaa ctgagaccac ttgcagcaat ttctttggct
     3001 tcttttccaa cgtagcggag atgccattct tctgccatgt agccagtctc cttttccttg
     3061 cctttaagat agcgaacaac aaagccatag tcagccgcat ggtccaagag ccactgggct
     3121 gccttttctt cagtaactaa atccccatct gtcccaatca aatcaaaagc aagacccgtc
     3181 tggtgttcac tgtaacctgg gcgtgctgag tagcgatctg ctgcttcctt accatcttga
     3241 ttgacatagt cttggtagag cttagcctga gtttcataac tcctaaaccc actgtattgg
     3301 tcactgattg gatagccctc agcctgcata gctgcgatta gtttgagcaa ctctgccttg
     3361 gctgttggat tttctcctgg attgtaatct tttgacaaag gataacgttt attagctagg
     3421 ataatctcat cgtatttccc ttggatacta taatagctcc ctttattgct aacttctgcc
     3481 tttttctgac tagaagcttg agatttgcta cctacagttc cttccggttg actgctttgc
     3541 tccgtttttt gagtgttttc ttcaactttg gttttttctt gcgaacaagc tgcaagggtc
     3601 aatgctagta aaccagataa aatgacatat ctttttttca tttctttctt cctctctctt
     3661 aggccaaata cttctccaat tcatgagata agattttaat catctcttcc agctctggcg
     3721 attgtacttg gcaatcttct gccgccattt cttcccaggg cacccaccag actgggccac
     3781 ggccattcaa accgtgactc ttcatatcac ctgctcttcg gggaaaaaga tgccaatgag
     3841 cgtgggcatc gccatttcct aggagttcaa tattcatctt ttcagcctca aatgctttgg
     3901 cgactgcttc ttggactaaa ctcatttcct ctaaaaagcg aagttttaca gaagtttcca
     3961 tatgatggag ttctgtgaca tgatcttttg ctaaaaataa ggtatagccc ttaaagtatt
     4021 ggtggtcacc aataacaaca tagcctgttt ctagttcttt tacaaagtag ggattttgcc
     4081 cagctttaat gagttcgatt ctctgacaga ttaagcacat tctatgatac cgcctcgctc
     4141 ttaagataag catcaaccat acgctcagtc gctactactg aatcgatgtg ggtgcgctca
     4201 taagagtgac tggactcaat accagctcca agaagtgcat gcttgacctc tgcacctgct
     4261 gacatcgctg ctgaagcgtc cgatccgtaa aatggataga tgtcgagctt aaatggaata
     4321 tcttgctctt tcgccaaagc tactaagtgt tgacggaagt catagtgata aggaccggaa
     4381 gcatccttta cacagataga tactgtgtac tcatccgtct gttggtcatc gcccatagct
     4441 cccatatcca cagccagata ttctactacc tcttctggaa tattggagtt agcaccatgg
     4501 cccacctctt caaagactga aaaagcaaag tgtgtcgtca tcggcaagtc aattccttct
     4561 tctttataaa ctcgaaggag atttagcaaa attgctgcgc tgaccttgtc gtccaaatgt
     4621 cgagacttga taaaaccagt ctctgtcacg acagttcgcg ggtcaaagct gatgaagtca
     4681 ccaacctcaa tacccaaggc acgtgtttct ttttcattgg tcactttttc gtctaaacga
     4741 acttccatat tgtcctgagt gcgttcagca gttcctgcat ctttgtagac atggcaagaa
     4801 gtctggtgga tgaggatagt tccagatacc gttttacctg tactagtcac atgaacggta
     4861 cagttttcac cctcaatcat gttccaagga aaaccaccga tccggtccaa tttgagacga
     4921 ccgtcaggtt tgacagcacg aacaatggct ccgagtgtgt ccacatgggc agttacatag
     4981 cgatgttctt cgtttttttg acctttgatg gtcacattga caccaccctt ggctgtgcga
     5041 actggctggt aaccaaaacc ttctagagtc ttgactaaat aattcgaaat ttcacgagtg
     5101 aagcccgttg gcgatgcgat ggctgtcagt tctttgatat attctactgt ttgattcatt
     5161 tcttcacctc tttcgctacc tattataaca catttatcat cggataaaaa aagaaaatca
     5221 ctcctgtaga cttggctaca aaagtgattt aagtgattat tccatttcaa aaacatcgct
     5281 ttcttgcttg tttggtagaa ccaatgagag caagattcca acaatggctg gcaccaacca
     5341 tgggagagat gccttggcaa aaggaagaac gctaacaaga tttgcaagaa actcaacctt
     5401 aaacgagctt cctagtacgc ttgcaatggc aataactgta accacagcaa ttgtcaactg
     5461 catacctggt tttgaaaggg caacaaattt gttgacaatg acaatcataa cgatagcaat
     5521 cgtgattggg tacaagataa ccagtactgg aattgagtac ttgataatcg catcaagacc
     5581 caaattggca atagcaaatc caatcaaggt aaaggctgtc gcataaacct tgtagctgat
     5641 ttgtgggaag cgctcattaa agaactcagc tgttgacaca atcaaaccaa cagtcgttgt
     5701 gaagcaggtt acggtaacca tagctgcaag gaagagttga gctgttgagc caaagatttc
     5761 ttgagtggct tgtgacaaga tgtaaacacc tggtgttcca cccttcatcg cttcagctgg
     5821 tactgggaaa tgatttccaa gaaaacctaa accgatgtaa agagcgctga aggcaagggc
     5881 aacaacgata ccaacaaccc aaatagttga aatgtattct ttcttacttg aaaatccaag
     5941 ttgtttcaag gtttgaactg cgattacgct aaaggccact gaggcaaggg cgtccaaggt
     6001 attgtaacct tctaggaaac ctgtaccaaa ggcagaagct tgataagcag ctgaagcagc
     6061 ttgaggactt gttccaccat atttgatagc tcccagaacg accaagataa caatcaaaat
     6121 tgcaaagact ggcgttaaaa tacgtccaat gcggtctaag atttttgatg gattaagcga
     6181 aatcaaatag gctgccgcaa aatacagaac cgtaaataca atcaagccaa gtcctttatt
     6241 tgcatccgac aaaagggggc taatccctac ttcgtaagct gttgtagcag tacgtggggt
     6301 agcaaagaat ggaccgattg acaagtaaag aactgagagg taaagagtcg caaaccaagg
     6361 cgctatcttc gttgaaatct cgtagatata tcctttagga tttagcgttc caataataag
     6421 ggtcaagacg gcgataccaa cgcctgaaaa gacaaaacct gcgatggcag gaagaaaatg
     6481 ttctccagat agagcaccta gagaaggcgg aaaaatcaag ttccccgcac caaaaaatat
     6541 tccaaacagg agcaaacctg ttagggtacc ttttttagcc ataaaaatct ccttcatatt
     6601 tataaaatac tgacctagta taccacgatt aggagtctga aaaaagcatc acgaggcaaa
     6661 tattaaatgt tttcaatttt cttaaaaata agaattatct aaaaataaaa actctcctac
     6721 ccagtccaca ccaagtagga gaaatgcaaa attttaaagt tcttcaaagg ctaacatgcc
     6781 accctggaca ttgataacat tataaccttg ttctaacagg aattggcaag cacgcgccga
     6841 tctcattcca gatttgcaaa taatataatg caagcgatct ttgtccaatt aatcataact
     6901 atcagccaat tgactaagcg gtaggttgtg ggcaccttct aaatgaagag ctgcaaactc
     6961 atccacttct ctcacatcca ctagagaaag ctggtcgttt tggtaaagct ggtaaaatgc
     7021 gtcaaaggct atttctttca ttctttttct tctaatactc ttcgaaaatc tcttcaaacc
     7081 acgtcagcgt cgccttaccg tgcgtatgtt accgacttcg tcagttttat ctgcaacctc
     7141 aaagctgtac tttgagcagc ctacgactag cttcctagtt tgctctttga ttttcattga
     7201 ctataaaatg gttttaattc tttttttcaa atctggcact acttctgcct caaaccaagg
     7261 atttttggcc atccagattt gatttcgtgg tgatgggtga actagcggaa aataggctgg
     7321 cagatagtct ttatagtgtt tcaccctctc cgttaccttc ccactgattt tctcctgtaa
     7381 atagtaggct tgggcatatt gcccaatcaa gagggttaac tgaatatcag gcaattcctg
     7441 taagagctgc ggatgccatt tttctgcaaa acctgtacga ggcggaagat cacccgactt
     7501 gccatgtcct ggaaagtaga aatccatagg caaaacagca aaataacctg aattgtaaaa
     7561 ggtatcttca tccacaccta gccagtcccg caagcggtca ccacttttat ctttccagta
     7621 aaggcctgct tcttgagttt taagtcccgg agcctgaccg atgatattga tgcgagcagt
     7681 ttttggcgct gcaaagagag gctcaatgcc acgctctgta tagctggcat tctgtgaatc
     7741 cgccatgata gcctgtttga ttctttcgat ttgagacatc tactttccct ccaaaaagaa
     7801 gtccaagcat aagatctcag acttctatcg ttttatttga tcaattcgta aatagcttcg
     7861 gcataaattg ctgctgctcg gaagagatcg tccaaggcaa taaattcatt ggcttggtgc
     7921 atggtatcaa ttgagtctgg gaacatagca ccataggcaa ctccgcgctc taacaagcga
     7981 ccaaaggttc caccaccgat gacttgttca tgaccttgta ggcctgtttg tttttcatag
     8041 acattcaaca aggtttgcac aagtggatct tccattggca catagtgagg ggtatgacca
     8101 tgttctgata gactgacaga agcaactggc aagttttcta ggattgactt gatttgttct
     8161 ggacttgttc cttttggata gcggatgtta agggcaatgg tattatcagc acttgtttca
     8221 tcgaagcgga agacgccggc attcatagaa agagcaccca tcttttcatc cacatgagca
     8281 atcttgagat tttcaccctc atgatcgttc aagagaattt tacctgcgat gtcaaggtag
     8341 tctttggctg gaccagcaaa gccaaactgg ctgaggaaga gggcaaggta agttgcgcca
     8401 ttgacacctg aagcaggcat agcaccgtgg gctgatttac caatgatcgt caccttgtat
     8461 tggccagctt cttcttggag ttctcctcta agtttgtgtt ctgcaacaaa ggcatctagt
     8521 ttagcttgca agtctgtcaa gtcacctgaa acgactgctg ttgctgattc tggtaccata
     8581 ttttcacgta aaccacctgt aaagctgtga agacgggctg cacctgtatt ttcacctgca
     8641 aagtggaggt attccgtgat gtttcctttt tcaccattga tgattggaaa ttcagcatct
     8701 ggtgagaaac caaagtctgg cttggcgagt cctacgtgct cgaagtagta gtccatatct
     8761 gcccagcctg attcttcgtc tgttccaacg atgaagcgaa ctttcttaga agttggaagg
     8821 cccaattctt tgatgatttt caaaccatag tagcaagctg ttgtaggtcc cttgtcatct
     8881 gaagcaccac gcgcataaag gcgaccatct ttgatagttg gtgtgtaagg gtctgtgtcc
     8941 caaccgctac cagctggaac cacgtccata tgggcaaaga ttccgagaac ttcttctcca
     9001 tcaccaaact caaaatgtcc tgcatagtta tcaacatttt tagttggata accatcacgg
     9061 tctgcgattt caaggaattt ttccaaggct tttactggac caggtccaaa tggatgttgg
     9121 gcatcagcct tgctatcatc acgttctgag ttgatttcca aaaggctaaa caagtcagcc
     9181 aagaggtctt ctttgcgttt ttctacttct gctgtaaaat caattgctat cattttttct
     9241 tcttcctatc ttttttcgat gatttcatct actggcaagc ggtagcttgg ttccaatttg
     9301 tcgtctgtgt aacccactgt gatcaagagt tctgggcgga aacggtcttc aatttccaaa
     9361 acctcattga cttttgattt gtcaaaacca aggataatat tggaaccaat tccttggtct
     9421 gtaagagcga gaaccaagtt catagcaacc aaacctgcat tgagtgctag gtagtcgctg
     9481 acttgttgtt cattgtagcg tgcaaattca gctggcaaat ttttcatgaa gtattgaagt
     9541 tgttcttctg agaaattgtt agcaccacca actcgggcaa tcttacgagc gcgtttggca
     9601 aggtctgtat ctgtaaatag ggcaatggtt acaggtgctg atgatacctg ctcaaagttt
     9661 gaaccataag ccaactttgc cagttcagca tttttctcac gaacaactac aaatttccaa
     9721 ggctggctgt tgtgggcgct tggcgccaag gttgcaattt cgatagccgt acgcacatct
     9781 tttggatcaa caggcttatc agtgaaatgc ttggtcgcat gacgtttttt atttaattca
     9841 agaaatttca taatcgattt ccttttctaa ttctactgct tccattctac cataatttga
     9901 aagagcttgc agggattttt catgattaag tttttctatc acagacataa aagatatata
     9961 ttggtttatc aggaaagttt ctgataaact agcaagtact ttacatttga atggagacag
    10021 tatgaaaaaa tttagcctat tactagctat cctaccattt ttggttgcct gtgggaatca
    10081 agctacaccc aaagagacta gcgctcaaaa gacaatcgtc cttgctacag ctggcgacgt
    10141 gccaccattt gactacgaag ataaaggcaa tctgacaggc ttcgatatcg aagttctaaa
    10201 ggcagtagat gaaaaactca gcgactacga gattcaattt caaagaaccg cctgggaaag
    10261 tatcttccca ggacttgatt ctggtcacta tcaggctgcg gccaataact tgagttacac
    10321 aaaagagcgt gctgaaaaat acctttactc gcttccaatt tccaacaatc ccctcgtcct
    10381 tgtcagcaac aagaaaaatc ctttgacttc tcttgaccag atcgctggta aaacaacaca
    10441 agaggatacc ggaacttcta acgctcaatt catcaataac tggaatcaga aacacactga
    10501 taatcccgct acaattaatt tttctggtga ggatattggt aaacgaatcc tagaccttgc
    10561 taacggagag tttgatttcc tagtttttga caaggtatcc gttcaaaaga ttatcaagga
    10621 ccgtggttta gacctctcag tcgttgattt accttctgca gatagcccca gcaattatat
    10681 cattttctca agcgaccaaa aagagtttaa agagcaattt gataaagcgc tcaaagaact
    10741 ctatcaagac ggaacccttg aaaaactcag caatacctat ctaggtggtt cttacctccc
    10801 agatcaatct cagttacaat aacactcttc gaaaatctct tcaaaccacg tcagctttat
    10861 ctgcaacctc aaagctgtgc tttgagcaac ctacggctag cttcctagtt tgctctttga
    10921 ttttcattga gtataagata tactaaaagc gatgggatca gccaatcgct tttttagttt
    10981 gcattggtta ttttaggaaa ctcttacaaa aaatcaaaaa aattcttcac atcctctaca
    11041 tacctatgct tttctattaa gcttgctaat agttccagat tgtgcctctg atagttatct
    11101 tcacgacgta gttcttcata catttcgata aagggaagcc ccttggattt ggcaaattct
    11161 aactcagcct cgtaatcata agcgacttta cgaaatagga tatttaccaa ttccccatct
    11221 tcaacctcta tcacggcata ctgggcacgg tgatttttta acgcctccca attaaaatag
    11281 ggcatgccaa tcgaccctgg attgatgatt tgttgccctt gactaccata acgaagcaac
    11341 tgcttgtgaa catgaccata aactgccacg tccgtttccg catctagcag ttggtcaaat
    11401 ttctctgtat cattctcaac tagcaagtca ccaccatagt ttttgtcagg taaattatga
    11461 gagatagaaa agcgcaatcc gtcaatttct ttcttttcca gcaaaggcaa gcttcgtagc
    11521 cagacaatcg ttgcaggatc cattcgctcc atcaaatact gtgtcatacg caagagctga
    11581 acttcctgtg ggtcttctaa gccatattgc ccatctaaag cctcaaggac acgatcatcc
    11641 caattgcctc gaacacttgc tgtgatagga aggtccttta gcagggcgac taagtcattt
    11701 gcgcctggac caggaagaaa aatatctccc agaagccagt attcactgac tccttgattt
    11761 ttagcatctg caatcactgc ttctagcgcc gtcacattgc catgaatatc tgataaaatt
    11821 gcgattttat ggtttattgt ggtttccttc cgtttggtaa tctactcttt cttctgctac
    11881 ttgaggcaag gcttctccct gcgggttcaa ctttctttgc acagcctctg caacgactct
    11941 aggtacccca acttcgacaa tctcatccac actggcttcc ttgattttgg tcaaagactt
    12001 gaaatgcttc ataagatttt gcttgcgttt aggtcccaga ccatcaatcc catccaattg
    12061 agatgagaaa gaatttttgg agcgcagttg gcggtggaag gtgatggcaa agcggtgcac
    12121 ctcatcttgg atgcgttgga ggaggaaaaa ttcctgagaa ttgcgagaca agtccaccac
    12181 ttccagcgga tctccaaaga gcaattcatg ggtttggtgc ttatcattct tttgcagacc
    12241 tgcaattgga atatccaagc ccagttcttc ttggatgact tgcttagcaa tattgacttg
    12301 accttgcccc ccatcaatca caatcaaatc tggaggagtc aaagcctcac gctgtactcg
    12361 accatagcgt ctgcgaatga cctctcgcat actggcatag tcgtctggcc cgactacggt
    12421 cttgatttta tacttacggt aatccttctt actaggcttg ccgttgacaa agaccaccat
    12481 ggctgaaaca ggactagttc ccatgatgtt ggagttatcg aaggactcga tgcgaactgg
    12541 ggttgggatt tgaagcaagc gtcctaaatt ttcaatagct ccttgggtct tctcgacaga
    12601 tttctctagc aggttgaact tctgctctag gctaacacgg gcatttttta tagctaaatt
    12661 gaccagctgc tttttctctc cacgttgagg cttaagaatc ttggaatcca ccaaggcctt
    12721 gacagcctct tcgtcaatat cctgcggaat cagtacctca ttgggaacta ggtgagattt
    12781 ttcttgatag aattgtccca cataggtcaa gaaatcctca tctggatcat tgaagtaggg
    12841 gaagagattg acatcgcgct cgatgagctt gccctgacga acaaagaaaa cctgcacaca
    12901 catccagccc ttatccacat agtagccaaa gacatcgcga ttttggagat ccttagccat
    12961 gacccgttgc ttggttcgaa gcgttccaat agcctgaatc aggtcacggt attccgccgc
    13021 acgttcaaac tccatagtct gggctgccgc tgccattttg ccctttagct catcaatgat
    13081 tttgttatcc tgccctttca gaaaatcaga aacctcctgg gccatagact tgaaataagc
    13141 ctcatccttc ttacagatgg tgtgagccat acactggccg atatggtaat aaaaacagac
    13201 cttagagggc gggttggtac acttacgaaa agggaatatc cgatccagca accgcttgat
    13261 ttcattggct gcccccacat cgggataagg tccaaaataa agacctccgt cctttttgac
    13321 ctgacgagtg ataatcaagc gtggatagcg ctcattggtg attttgatga aaggatagga
    13381 cttgtcatcc ttgagcatga tattgtactt gggcttgttt tccttgatca ggttgatttc
    13441 taggagaagt gcctcaatat tagactccgt aacaataaat tcaaaatcca caatttcaga
    13501 caccagagcc tctgtcttgg tatcatgact tccacgaaaa taggaccgta ctcgattacg
    13561 cagattttta gcctttccta catagataat ggtgccattt ttatccttat gaatgtagca
    13621 accagggctg gtcggcaaga gctctagttt tgatttaatc aagttgttca tagttccatt
    13681 atagcaaaaa aagtagggaa agatagtacc ctactcacta gtctcatata tttttcggag
    13741 gtttgcaaca tcctcttcct ggataccata aaaggaacct gctggttgca tgacagactt
    13801 ctcatctgta tggtccaagc caatcgcatg acctaactca tgttctgccg tatggacaag
    13861 gcgttcatag gagtagccat agtatggatt ggacaaataa taatgattca accgcaccgt
    13921 tacggacaag aattgccctg ttaagagatt agtttgactt tccgcctctc ctgccacagg
    13981 agtgcctccg tcgttcatct ccgtagccgt aatatccgcc ttactagact cagtcacgag
    14041 ttcaaagtta aaagcaccag tttgattcca gttctggatt gcttctaaat aagcctcttg
    14101 aaagcgtgaa tccatctgcg gatccaggta aatacgagca gagacctgtg gccaccttcc
    14161 ttcagaatgc tggtgactat ctgtctggct taacttaggc agttgccctg ttttctccca
    14221 ttggtcaata ctttgttgac caatttttac tgaccgttct gcttgcttta gcgctccttg
    14281 aaaatccccg ttcagatacc agagaagtcc gaaagcaagc acacataaga gcacaactat
    14341 ccaaaccaga cgccaaaaca aacgccacac aaaagaaaag aaagccccta tcaaacgaaa
    14401 aagccagcgc atgtctctcc acctttctag caaataaaaa ttattttact aaaagaagct
    14461 aaaagaaatc taaatactga ctttttcatc ttaacgtcct actatttttt tgagtaactg
    14521 gatagctttg tattttaaag gcgatggatg gtaacggaaa gtacctgctt tgcgtacaat
    14581 atagccatta aaattctgtt taaaacgcaa aacaccatca cttccatcaa aaatcccttg
    14641 aatgcctagg aagttgtatt taggtattcc acgttttatg ctttccaaca taacatattt
    14701 ttgaagcagt gcaggggcat agaacttatt aaactcagtg taggaaccac taaagagata
    14761 agtcgtttcc tgaggcatat aaacaaataa actcccagct aaaacaatat cttcttctcc
    14821 atatttttca atcaagtctc gcgcttctgc ttttcgaact tcaaacgttt caaattgact
    14881 agaatattct ctcagttgat tttgtttttt ctcagaatga ggatttttac tcaaatcaag
    14941 tcgcaacttg tccaagtttt cttctagttt actttgttca ccttgcaatt tgctcatata
    15001 gtccgaaaaa ttcaagcttg ctatgagaaa ctccgcttgt tctccaaaag tatcataaaa
    15061 atgctcataa tattctaaac ttttatcact atattctcta cgttcagagg tttcttttgt
    15121 tatattctta aaaatcgata gttcttcacg ttttaacttt ttcaaccgaa tgccaaaggt
    15181 ttcagccttt ttcaccaagg gtttaccctt tttgctaaaa cttttaagca aactcttttc
    15241 agttaattca gttaaatctt tatagtataa ccaatctggt tctccacctg ggtaacctgt
    15301 tgttaagcca tcaaattgat aacctaaatc agtcaaacct tgaataatac tttttttctc
    15361 agcatctatt ggattacctt ggctatcaaa agtttgataa gtttcataag gttttacaag
    15421 caactctaat acaccatttt gcttggcata ttcttttaac tctgcataaa aaactggaag
    15481 agcatcttgt tgggtataaa tcggccccga attgagttcc atatgcagac cacccagcat
    15541 gggcaagcta taaaccagag ctgcaacttg aatttctcct tcttgtttca aagcaagata
    15601 aacaattcga gcccctcttt tttctagcaa atcccccatc tggacagatt gcataaagga
    15661 acgagaagaa acctgatcag aataagtctg aaactcttct ttcgtgagtg ttgttagtgc
    15721 catatactta ctttctatgt ttttttctta atgttttacg gaaatcaaga gcaagtctta
    15781 acagaggata gagaggatga gtgggcattg taaattcacc caagtattct tcaatcgttg
    15841 gattaaattt ttccttaaaa tgataaagtc caccattgag agagttttca acaccaccta
    15901 aattttgcca gaccatacct cgctcaaagg catagcgagc cgtttcatac catgttaaaa
    15961 ttggtgcatt gtaacgttta aaatcatcat ccataccagc atatatattg acagaggtag
    16021 taccaaattc caaactcaaa gtagccgcta aaggaactct cgcttgacct acatctatat
    16081 attcctgcaa gaaggtcaat tcctctaaca aacgttcttt ttccttcttc tgcgcttcta
    16141 cttttgaaat tcgagtcgac tcagtaaagg tctcttccaa ggctctattt ttcgctaact
    16201 gttcttctaa ctcttgcgaa cgtttagaaa catccaaggt ggccaaggtg atataggcct
    16261 tgtccttaaa attatctaac aattttttat aataggcttc attcctcaaa tgaatctctt
    16321 ttcgcttctc agtttttttc atcaactccg aaaatgaatc taatagttcc agtccaccat
    16381 attgaatctc aagccctttg tttcgtgctg ttcgaatagc ctgttttgtt gacttggaaa
    16441 gtttatcttc ttcaaaattt tccttgtata ttttcgcctg aatacgaggt tgaatggtgt
    16501 ctcccatttc ctccgttttt cctgaccacc ttactcccat ttgttgcaaa ctatcaataa
    16561 tagccagatt ttcaggaaat tctgtctttt cctgattgat taaactttga gataggcaaa
    16621 tacttgggtc aaaagtcaca aaaaccgctc tcttactgcg agcataggac ttaatagact
    16681 gaatggcaaa attcaagagt tctttatccc cataatccaa tataggtcct cttgggatgt
    16741 aaaacatttt atagcctagc ggaagagttc taatcaaaat actagctgtc gccagtaatt
    16801 tttcttccct gtaaacacca aacttctcat gttgccaatt agacttaact tcctcccaag
    16861 cactactttg taatacattg gctaattcat gttctttgac aaactgatca tattctaatg
    16921 tgggaatgcc aatttgataa cggtacattt cctactctct ttcctccagt attttattac
    16981 tattctacta ctttcgtttg aaaagtctag tgaaaacata ttttatttta gttctacttc
    17041 ccctatgctg aagttcaaac taagtcagtc tctcttctaa tttgaaatca attggtaggg
    17101 ttgttaaaaa aacttccaat tgtttttccc agtagtacca ctcgtgagtt ccagcgctat
    17161 ggctataggt cacatcaaaa cctagttttt tgagattttt cactgcaaga ttattggctt
    17221 cgtacaagaa atcctgttcg ccacaccacg cccaaagttt ggtcttttta tccgattttt
    17281 tagccagact ttcaagagaa tagggactag ttgtccagtc tttaatctct ccaaaaacac
    17341 ctctccagta ggctggcgtt cccagatttt gactctcagg agaaaaatct tgaaagctca
    17401 atgcacctga aaagctagct gcatgagaaa aacgatttgt cgcaagagcc agtttgaaac
    17461 agccgtagcc tcccatagaa agaccagcga taaaggtctt ttcacgcttg ctagtcatat
    17521 tagggaagaa gcgtttcaga acctgtggca attcctctgc tagagccgtg tagtagtcaa
    17581 aaccatactg ggtatcggtg taccaaccat tgctggtatt gggcataaca acgatgagat
    17641 tagttcctcg aagcaagcgt tctacattgg tccgcttaag ccaactatta tgattgccag
    17701 acatcccgtg caaaaggtac aagacgggaa tatcttcaca ctctggttct tccactcgat
    17761 tggcatcagg gtagaggaca ttcacccccc actccatatc caatacttgt gagtaatact
    17821 cgattttcat tactgccatg attttctcct tctatttttc tataagaaaa agccgaaact
    17881 cgactttctc tctgtttatt ttaacgatta ttttgcttcc atgactactg gtaaaatggc
    17941 tgggcgacgc ttggtttggt caaagagata cttggtcaaa ttatctcgaa ccttcccttt
    18001 aagatctgcc cagtcaaagt catctccttg aagatactct tctaccgttt ggttaatcaa
    18061 ttctgaactt tcacggagaa tatcgcgact cttcttgaga taaacaaatc cacgcgtgtg
    18121 aacacgagcc ctagccacaa ttttcttctc acgacggttg actgtaatag ccacgatgaa
    18181 aattccatcc tctgacaaga ccttacggtc acgaagaaca acatttccaa catcaccaat
    18241 ggcattccca tcaatcaaga tatctcctgc tgaaaccgat ccagctggaa caaagtctcc
    18301 attctcgtaa gccatggtcg tccccttttt aggaatgaag atgcgttctg gcaacatccc
    18361 aactgccatg gcagccttag cgtgagcatc caactcacga tactcccctt ggacagggaa
    18421 gaggtactta ggttgcaaaa gattgatcat cagctgcaaa tcacgcacat ttccgtgccc
    18481 tgatacatgt aaactttggg taatcaattt gacaacccca cctgcctgat aaatcatatt
    18541 ttccacacgc gcaacaaagg cttctttagc aatagacgga gccgtagcaa tatagaccag
    18601 gtccccatcc ttgatttcta cataacgatg gcgaccaatc gacatcttac gaagtccatt
    18661 gataggttca cccatacgac ctgtctcaag aataatcaac tcatggtctt caaatcgaga
    18721 catatcttta ggcttaatca agagaatttc gttggctaaa gacaacttct taagacgaat
    18781 cgctgtgcgg acgatatttt caatatcaaa tcctgtcaag acgatacgtc gacctgtttt
    18841 atccgcagcg tcaaaaatct gctgaatacg agaaagatta ctggaaacag ctgcaacgat
    18901 gatacgacct tcccagtcag caatagtttg ggtaatttca tccctaactt cactttcact
    18961 agccacctga atattgctgt ctgcattggc cgaatcactg aggagagcca ggacgccgtc
    19021 acgaccaatc tctgccaaac gagcaaaatc agttgcataa gattcactag ccgtttggtc
    19081 aaatttgaag tcacctgtat aaacgatgct tccttccgat gtcttcaaga caattcccag
    19141 actctctgga acggagtaag tcgtagggaa gaaggaaacc actgtcccac caaaatcaat
    19201 ctccgtattc tcatcaatga catggaaatc attaaatttc ttaacggcat catttccttt
    19261 gacaaagagc tttgccaact caatggtcaa ctcagaccca aatacaggaa ctttagcctc
    19321 tgccaagaga tacggtagag caccaatggc atccgcatgc ccgtgggtca agaaaacccc
    19381 agcaatacgg tcgctatttt caaaaaggta atccatgttt ggaatcacca catcgacccc
    19441 taattgttca ttttcaggat attttaaccc tacattcaaa acaaaaatgg actctccaat
    19501 ttcagcaatg tacatatttt ttccattctc acgcacacca ccaagtgttg ttaaactgat
    19561 attactcatt tttcctccaa aatcttagtt tatcttgatt atagggcaat tctaccctct
    19621 tattctaaaa gttctgatac tttcagccga atcttttcct accattatac catttttttg
    19681 atgattttca aaatgaaggt ctgttttcaa aaaagagttg atttcccaac tctttcctaa
    19741 cttctactct ttttccatca aaaaatcata aatttcttgc accgtaccca gcgccatcat
    19801 ttcttggtct ttaacggttt gtttgagatt ttggtaaatt tgactttctc ctatctcccg
    19861 ctttggcgcc tctttattga ctgtcatcac accatctttt atcgtcacaa agcctagttc
    19921 ttcaaatact tgaatcatct tgaccagcaa gatttgttga atattaagat atgcagccaa
    19981 atctttcagc ttgtagcgaa tatcaaactc tgggaaccgg taaatagtct tgtacaattt
    20041 ggcaaactga tctctagtcc cataacctgt cagataataa gccttgtcaa tatcattttt
    20101 gaaatagaca gcagagaaat gctgttcctg aaaaatggtc ttcagctgag taatatcctc
    20161 tggaatgttt tttacgacaa cagcttcact agccgcaaga tttggcagtt ctccaggaaa
    20221 atccaagact ggaacacctt ctggcaagac tgcatttttt ccacgaatgt taaaaagttg
    20281 aacaccttcc actcgcgcat ccaccatcat caactggagg gcagtttggc cattccattg
    20341 gttgacagac aatttaaccg ctaactctag attcttggtt tgagaaaact ctgtcgccca
    20401 tctgccttga ccaaaggcta ccacttcaaa actcgcctca cccttggaaa ttttcagctt
    20461 tagatgggca ttacctgccc ccatagtacg agcactttcg acctgaaaat tcttgatata
    20521 aaaaataggt ttctgattat ccattccaaa aggagctaaa cgttcaaaac ttttgaccgt
    20581 ttccaagcta agtgcctcca aatccaactc ttcatctagg tttaacttat tcttgccacc
    20641 agcatctgca cctttttcac gaacataatc ttccaaaacc tgagataaat ctgagagttg
    20701 ctcaacttcc aacgtcatac ccgctgcacc tgcatgacct ccaaaggcga tgaagaggtc
    20761 tcgatgggga tccagagctt caaaaatatc gaccgcttcc acactacgag cactgccctt
    20821 ggcacgaccg tcttctatat taagaacaat gactgtctgt cccaattctt ccaataaacg
    20881 accagccacg attcctagaa ccccaggatt ccagccttcc ttggccaaga cctgaacctt
    20941 cttctcagga tccaccatgg tcttggcttc ttcatagata gactgaacga tttccttgcg
    21001 ctcttcgttt ttctggtgaa tcataagggc aatctcatgc gcttcctcat catcaaatcc
    21061 agtcaacaaa tcaatggcag gattgggatc atccaagcga cccaaggcat tcaaacgagg
    21121 agcaatctgg aaaccaaccg tttcttctgt tacttcgttg gcaccaatcc cagccatgtc
    21181 cagcatttct tgcagaccaa tgcgctgggt atgacccaac atttccagac catattgaac
    21241 taagatacga ttttcatccg tcagactcac catatctgca atagttccaa tagcgaccaa
    21301 atcaagcaat tccacttgca cttcttctaa cagggcacaa gccaacttga aagcaactcc
    21361 acaaccagcc aaatatttaa aaggataatc cgcatctgga tgttcaggat ggacaatagc
    21421 ataagcatct ggcagggttt caggcatgga atgatggtct gtgacaatga catctactcc
    21481 catagactga gccaatgcaa tagcctcatg accagcaacc ccattgtcca ccgtcacaat
    21541 caaggaaatc ccttcttgct cgataaagta tttataaaca ctagcattag ggccatagcc
    21601 atcggtaaaa cgatttggca ggtaaactcg gcactcagca ccaagttgtt ccaaactttc
    21661 cttcacaata gaagccgaag tcatgccatc cgcatcatag tctccataaa cgagaatatt
    21721 ttccccttct tcaatagcct gacgaatccg ctccactgcc ttgtccatat catggagcag
    21781 ataagcatca tgtaagtcct ccaaggaagg ttctaaaaac ttcttcagac tttcttggtc
    21841 ctgaatccct ctctcaaaca ataaccgagc cacctcagga cccagtccag ccttcttggc
    21901 tatctttgta aaatccgcat cttctacctg cagggcaaac tgccattcat aagtaggtgt
    21961 tatcaaaaag acatccactc tttctaagaa ttctattgct tcattataac atgatttaga
    22021 cgttttctct atccagattg cttttttata acattttata gtatattgaa actagaatag
    22081 tacacctcta cttctaaaat attgttagaa atcgatttga ctgtcccgat cgatttgtcc
    22141 tgttcttatt tcaatatagt gaattttttc agatatggtt tgacaagaac attcttttat
    22201 tgtagaatcg tgttataaaa tctaacataa aggagatctc tcatggcttt agtagaattt
    22261 aaaaacgtcg aaaaatatta cggagactac cacgcactcc gcaacatcaa tctccgtttt
    22321 gaaaaaggac aagttgttgt cctgcttgga ccttctggct ctgggaagtc cactcttatc
    22381 cgtacgatca atggtttaga ggctgttgac aaaggaagtc tcctagtcaa tgggcaccaa
    22441 gttgctggtg ccagccagaa agatttggta cctcttcgca aggaagtcgg catggttttt
    22501 caacatttta acctttatac acacaaaact gtgttagaaa acgtgacact tgcgcccatt
    22561 aaagttctag gaattgataa aaaagaagct gaaaaaaccg cccaaaaata tctggaattt
    22621 gtaaatatgt gggacaagaa agattcctat cccgccatgc tatctggtgg acaaaaacag
    22681 cggatcgcca tcgctcgtgg tcttgctatg catccggaac tcctcctctt tgatgaacca
    22741 acatctgctc ttgatcctga gactatcgga gatgttctag cagttatgca gaaactggcg
    22801 catgatggga tgaacatgat catcgttacc cacgaaatgg gctttgctcg agaggttgcg
    22861 gaccgcatta tctttatggc cgacggagaa gttttagtag atatgacaga tgtcgataac
    22921 ttttttgaca atccaagcga acctcgtgcc caacaattcc tcagcaaaat tatcaaccac
    22981 gaaagtgaca aagtcaaata aggaggcgcc tatgaaaaaa aaattctttt tatcagcatt
    23041 attgattagc cttttcggcc ttgctgctgc caaaccagtc caggctgata ctagtatcgc
    23101 agacattcaa aaaagaggcg aactggttgt cggtgtcaaa caagacgttc ccaattttgg
    23161 ttacaaagat cccaagaccg gtacttattc tggtatcgaa accgacttgg ccaagatggt
    23221 agctgatgaa ctcaaggtca agattcgcta tgtgccggtt acagcacaaa cccgcgcccc
    23281 cttctagaca atgaacaggt cgatatggat atcgcgacct ttaccatcac ggacgaacgc
    23341 aaaaaactct acaactttac cagtccctac tacacagacg cttctggatt tttggtcaat
    23401 aaatctgcca aaatcaaaaa gattgaggac ctaaacggca aaaccatcgg agtcgcccaa
    23461 ggttctatca cccaacgcct aattactgaa ctgggtaaaa agaaaggtct gaagtttaaa
    23521 ttcgtcgaac ttggttccta cccagaattg attacttccc tgcacgctca tcgtatcgat
    23581 gccttttccg ttgaccgctc tattctatct ggctacacta ataaacggac agcactacta
    23641 gatgatagtt tcaagccatc tgactacggt attgttacca agaaatcaaa tacagagctc
    23701 aacgactatc ttgataactt ggttactaaa tggagcaagg atggtagttt gcagaaactt
    23761 tatgaccgtt acaagctcaa accatctagt cataccgcag attaaggagg ataccctatg
    23821 acagatttat catcttggac agcctatttt caggattttg gacaattttt caatggtttc
    23881 ctcttcaccc ttgccctagc gattggatcc tttatcctcg ccatggtctt aggaatcttc
    23941 tttggtgcca tgtcaaccag taaacgtcca attttacgca ttttagctcg catcttcgtg
    24001 gaattttacc aaaacactcc cctcttggtg cagtttgtta ttgtttttta tggcctacct
    24061 cttatcagtg accatatcat catgattcca atttattgga cagccgttct ctgcgtggga
    24121 ctctatcacg gcgcttatat cgctgaggtt attcgttcag ggattcagtc tattcctagt
    24181 ggtcagatgg aggccgcctt gtcgcaaggt tttacctata tcagtgccat gcgcttgatt
    24241 atcttgcctc aggccttccg catcattctc cctccattga ccaaccaaat tgttaacctc
    24301 atcaagaaca catctactgt agctatcatc tctggagtag acttgatgtt tgtgactaag
    24361 tcttggtcgg ctctcaacgg aaactatatc ccagcctttt taggtgctgc tcttctctac
    24421 tttgccctat gcttccctgt tgcccagttt ggtcgcaaga tggagcaagt caataaaaaa
    24481 gcctattcac tttaggaggt tactatggaa tctattttag aaattttaac cccagataac
    24541 ctagtcttta tctttaaagg atttggcttg accctctata tttctctgat tgccatcatc
    24601 ctctctacta tcatcggtac cgtgcttgcc gtcatgcgaa atggaaaaaa tcctatctta
    24661 cgcattattt ccagtattta tatcgagttt gtgcgcaacg ttcccaacct tctctggatt
    24721 tttactatct ttttggtgtt caaaatgaag tccacaccag caggtattac agcctttact
    24781 ctctttacat cagcagcctt ggctgagatt attcgaggcg gtctcaatgc cgtagacaag
    24841 ggacaatacg aagcaggaat gtcacaaggc ttcacctcag cccaaatcct ctactacatc
    24901 attctcccac aagccatccg caaaatgcta ccagccatca tttctcagtt tgttaccgtg
    24961 attaaggata ccagtctcct ctactctgtt atcgccctac aagaactctt tggagccagc
    25021 caaattctca tgggccgtta tttcgaacca gagcaggtct tcagtcttta catcctgatt
    25081 gccctcatct acttcagctt taacctagca atttctaacc tgtctcatat gctagcaaaa
    25141 cgttggcaac aagctgcaga ataacaaatt agctctctag ttcattggag agttttttga
    25201 tgatagtaga tatttataga cctcaatttg acaccataca ttttctatga taaaatgtaa
    25261 caaatttatt tacaacaaat cgaaatctaa atgaaatgga attttctatg aaatcaatca
    25321 aaggactact ctttatcata gctagtttta tcttgactct tttgacttgg atgaacactt
    25381 ctccccaatt catgattcca ggactagctt taacaagcct atctctgact tttatcctag
    25441 ccactcgtct cccactacta gaaagctggt ttcacggttt ggagaaggtc tacaccgtcc
    25501 acaaattcac agcctttctc tcaatcatcc tactaatctt tcataacttt agtatgggcg
    25561 gtttgtgggg ctctcgctta gctgctcagt ttggcaatct tgccatctat atctttgcca
    25621 gcatcatcct tgtcgcctat ttaggcaaat acatccaata cgaagcttgg cgatggattc
    25681 accgcctggt ttacctagcc tatattttag gactctttca catctacatg ataatgggca
    25741 atcgtctcct tacatttaat cttctaagtt ttcttgttgg tagctatgcc cttttaggct
    25801 tactagctgg tttttatatc atttttctat atcaaaagat ttccttcccc tatctaggga
    25861 aaattaccca tctcaaacgc ttaaatcacg atactagaga aattcaaatc catcttagca
    25921 gacctttcaa ctatcaatca ggacaatttg cctttctaaa gattttccaa gaaggctttg
    25981 aaagtgctcc gcatcccttt tctatctcag gaggtcatgg tcaaactctt tactttactg
    26041 ttaaaaattc aggcgaccat accaagaata tctatgataa tcttcaagcc ggcagcaaag
    26101 taaccctaga cagagcttac ggacacatga tcatagaaga aggacgagaa aatcaggttt
    26161 ggattgctgg aggtattggg attaccccct tcatctctta catccgtgaa catcctattt
    26221 tagataaaca ggttcacttc tactatagct tccgtggaga tgaaaatgca gtctacctag
    26281 atttactccg taactatgct cagaaaaatc ctaattttga actccatcta atcgacagta
    26341 cgaaagacgg ctatcttaat tttgaacaaa aagaagtgcc cgaacatgca accgtctata
    26401 tgtgtggtcc tatttctatg atgaaggcac ttgccaaaca gattaagaaa caaaatccaa
    26461 aaacagagct tatttacgaa ggattcaagt tcaaataagt aatcatactc tcctgggatt
    26521 tcccaggaga gttttttata gccaaatgaa ataagaccgg aacgatggaa ttttggcatt
    26581 caaatcaatt gataagaata ttttatagtg gagtgaaata ggatacgaac aaattgatta
    26641 ggaaaatcaa atgaatttat agaaatcttt tagcagttat gttgtcctat tctagtttca
    26701 aaacgctatg gaagcagcat tgtgctagtc tagattcagt ttactatact aaaacgagta
    26761 gcttgaaatc aaaaaaccca ccctcacagg caggttttat ctgtattatt cagctagatt
    26821 atgctttacc ttctgaaccg aatacgtcga tacgttcttc aaccgatgct tggatagctt
    26881 ttacaccgtc agccaagaat ttacgtgggt cgaagagttt tttcttgtcg tattctgctt
    26941 cgtttgcttc gtaatcacga gcaaatttac gagttgcgtt agcgaatgcg atttggcatt
    27001 ctgtgttaac gttaactttg gcaacaccaa gtttgatagc tgcttggatt tgctcatcag
    27061 gaatacctga tccaccgtgc aatacgattg ggaatcctgg aagagcttct gtcaattttt
    27121 gcaagtggtc aaggtcaaga ccttcccagt ttactgggta agggccgtgg atgttaccga
    27181 taccagctgc caagaagtcg ataccagttt caaccattgc tttagcgtct tcgattggag
    27241 ccaattcacc tttaccgatg attccgtctt cttcaccacc gatagtacca acttcagctt
    27301 ctactgagat acctttagcg tgtgcttttt caacaacttc tttagccaat ttaaggtttt
    27361 cttcaactgg aaggtgtgaa ccgtcaaaca tgattgaagt ataaccaact tcgatacact
    27421 caagtgcatc ttcgtagtga ccgtggtcaa ggtggatagc tactggtaca gtgataccca
    27481 ttgattcaac aaggttagcg atcaagttgc gagcaacttt gtaaccaccc atgtatttag
    27541 cagcacccat tgaagtttgg atcaaaactg gagctttttt agcttctgct gcgcgcaaga
    27601 tagcttgagt ccactcaagg ttgtttgtgt taaatccacc aactgcataa ccgttgtcac
    27661 gggctgcttg gacaaatttt tctgctgaaa cgattgccat tttatcaggc ctcctgtata
    27721 tttttatggg tcatcccatt tacattgttc attttatcac tttttgccaa aaaaatctag
    27781 tttttcccgc agtttcgatt gattttcttc taactccatc tatgtaaacc ctttctctcc
    27841 ctagtcttgg acgacttttg gaaaatctat aaagaaggtt aaacgattct cctccatctc
    27901 gaaacgataa gctaattttt catgttctaa tagactctta accacaaaaa gccccatacc
    27961 agaccccttg accttgcgac tggcattgtc agaaaaagac tgggctagtt tttcttgttc
    28021 ctctgagcta cagctatttt cgataaaaag ttctccttct ctttctccaa ttcgaactaa
    28081 gccacctgga acagagtgct taatggcatt gctgatgaga ttagaaagaa tcaacttcat
    28141 aactgatggg tttagataag cctgctgatg ggtcaaacta ttgtctatct ggagctctct
    28201 ttccttggct agcaaggcat aatctttgac cagatttttc gtcatctgga ggaggtcaat
    28261 tgtttcccta tcatctcgca attcctgcac agaagagagg gaaagtatct gcagaacatg
    28321 gtgattgagt tcatccacaa tccccaaggc aactcccaga tactggtctc tatccttata
    28381 acgaccgata ttctctctca tattttcgat taggattttc aaactagcca gcggtgtttt
    28441 caattcatga gaagctcctc gtaggaattc gaccttcatc ttctccagct ggagaatggc
    28501 ttcattcttt tcatgcaagt ccgcaataac agtcaagaga tgctggtaga ggctattgat
    28561 ttgttccttg agattaccta tctcatcctt agaatccacg cgcaatcgca cttgggaatc
    28621 caggtccatc atccgacggg tcacccgctt gatttccaaa atcggtgcaa caatagtccg
    28681 agcgtagatg taggccacca agagggaaat cagaaaggag gccagcaagg tatagggaag
    28741 aaactggaga ctgatttgct ccgcttcctt ttgtaaatcc atggaagcta gaaactggag
    28801 aatcatagta ccaccgtctt gcgttttcac ctcgcgctcc tcaataaaga gagaggttgt
    28861 ctggcggtct gtgtccagag gaagactgtc cttgacttct aacttgtcct cggtcatctc
    28921 acctttgacg gtccccttga tatcactagt ctgggaatac aagtctaaca cttgctcgat
    28981 actctgccta tctttccctt ctagggactg ggcaatggct gttgcctttt gaccaatggt
    29041 ttcctgacga tgactcagat aagtcgaagg aaaaagaaaa taaatagcta aatgaaggca
    29101 gataaccaga acactaaata tcgagaaggt atagataaat atctttgtaa ataaacctgt
    29161 tcgtttcatt ttcgctccaa tttataacca acattgcgca cagtgaagat acaatccaag
    29221 tctagctttt tccgcaattc cttgatataa acatcaataa cacggtcaaa gggaacctca
    29281 tctgtcgctt tccagacggc atcgataatc tgagaccgag tcaaggcccg gccttcattt
    29341 ttcactagat agtccagaat ttccaactct ttggcattga taggcacttc ttgacctgcg
    29401 aggcttgcac tgtagctttc aaagtccacc ttggtatcct tgtaagaaaa gattcgtcct
    29461 gtatcgtagt agcgcttgaa aatcgcgtcc accctcactt ttaagaggga gagggagaaa
    29521 ggtttttcca gatagccatc tgccaaagag gcaaaggcac tcatcttgta ttcctcatcc
    29581 tgaaaagctg tcaacatcaa gacaggaacc tgactggttt tacgaatctc agctaggact
    29641 tctaagccgt taagcttggg catctggata tccagtaaaa ccagggccac ctcatagcta
    29701 gaaaattgct ccagagcttc ctgaccgtcc gctgcctcaa tagtttcata gccacaatcc
    29761 gtcaaataat cactgacccc ctcacggatc atctcttcat cttctacaat taaaattttc
    29821 atactttaac tgctctctat tttttatttt tcttagaata aatacctact ctattttcta
    29881 ttatagtctc ttgctggcct tttgtctgta agcaactgac cactagataa aacgttgtga
    29941 aattcctttc tcataaattc cataacttta gtatattata tttaagcact aaagtacaaa
    30001 gaaagcaact gaaagcaatg attttcacca ctgctttcag atttattttg aattgttaaa
    30061 tagctattcc tatccactat tcttgaatag aaacacaaga tgcaatcttt attccagact
    30121 cattttttca aatttattca ccatccagca agagctcttt tggttgtttt ctaaggagat
    30181 tgcttgaagc aagcgccata acgagaacca ctagaaccaa ggcaaggaca aaaatgatga
    30241 taaagtctga tgtctgaatg gaaatgtcta ggctcgacaa ggtcttgcta aagccatcta
    30301 cttctgcacc gccaccaagg ttagaggctt gagccgcctt actagcctgt ttggcaacac
    30361 ctgaagtcac attggcaagg acagtgtttc caattgcacg ggcagtgtaa ttagctagga
    30421 agtaagcaga aactagagca gggatagcaa tcaagataga ttcggtgatg aattgaccca
    30481 agatacttgc ctgcttgagg ccgatagaga ggagaattcc cacttccttg cgacgggcgt
    30541 tgatccaaag gctgagcaag agggcaagga ggagaactga gaagctcaag ctaccccaga
    30601 agaggaggtt ggccatcttg tacataccag agatagattg ctcaagagct gggtagttag
    30661 aggagctctt gacgagtgtg tagctcttcc agttgatacc actgatgcca ttcaactctt
    30721 tcataacatc atccaagttc ttgtctgctg ttacaaagaa ggttgcgtcc ccataaatgg
    30781 ctgtgtcttc tgtgtatcca taaagttttg cagcagtgtg aatgtctgta atagctgtgt
    30841 tttcgtaaag ttcttgtgag taggttactg ctgacttatt atgaccatca aagagtccct
    30901 tgattgtcac ttcaactgtt tccttggctc ctttttcatt atctgcatcg tagatattag
    30961 agtccagttt aaccttgtcc cctactttcc agccgtgttt ggctgccaag tccttgtgca
    31021 agaggatttt atccttgtcg tcgttggtta agtgctctcc ttcgactagt ttataagaac
    31081 cagagacaaa cttgtcttct ttagaggagt cattgacacc tgtaatcatc aagctacttc
    31141 caaaacgttt ggcacgatca gcagtgagat tcttcttggt ttctggcgtt tcaatcaggt
    31201 catatccagt caaatctccg atagcgttga tacgtttgac ataagactca atggccttgt
    31261 tttcggtgat ttttttgata tcttcaccct tgatattccc agcaccacga ggcgttcctt
    31321 ggttgacgcg acgattgatt tgcatggaga agctattggt gatattttta aaggtctcct
    31381 gagaagcctt ggcagtagct cccttgattg acaagccgac caaactcaag ctcgccatga
    31441 ggagaataat caggaagatg acaatcgatt tgaaaaactt ccttgtaaca taggcaaatg
    31501 cgttgtgtaa catagattcc ctttctagat tttgttttaa tcattctatc aaaataagct
    31561 caaattattt actagtattg cgcgtttcag tcagtttctt atcctttaat tcaagtgtaa
    31621 tatctgacgc ttgtgccact tctttactgt gagttacgac aatcacacat ttacctgttt
    31681 tctgggcaag tgatttgagt agttcgacaa tatctccagc agttttagga tccagatttc
    31741 ctgttggctc atcagctaga ataactggag cttctgagac caaactgcga gcaatggcaa
    31801 cacgttgctg ttgaccacct gataactgga gaacattccg cttgatctgg ctttcatcca
    31861 aaccaagctc aagaagtgta ttcttgcttg cctttttgtt gaccaatcgg atattttcca
    31921 gcggagaaag ataatctatc aagttataat tttgaaagac cagggaaata tggtgcatgc
    31981 gatggtaaga atagcccttc ttacgaatat cctctccttg aaaaaggata gaaccttcaa
    32041 caggactatc tagaccagca agtagggaca agagtgtgga ttttcctgct cctgactccc
    32101 caataatact gtaaaatttt ccgggttcaa aattataatc gatctgatat aggactgctt
    32161 cagcagtatt cttataacgg taggtaacat cttgtaattg taataaagtc atgatttctc
    32221 cttcttaact aatagatgat aaaatttctt tcggtgattt tctaaataag aataggaaac
    32281 aaagggctac agataagcaa ctaagcagaa ctagaaaaac ataggattct gcaaaagata
    32341 agatgctagt tgataaactg cttgctttgg ctagtgtatc ttgtaagctt acctgatctc
    32401 cacttgctag tagagtttgg agtaggtaag ttgtgattcc gtttcctgca acaaatgctg
    32461 gaagcaaagc tccaagagat accaaaacta cctctaaaca gaattgtagg aagatcgagc
    32521 tcttgccttt tccaagtgca agtaaaatcc ccacttcata gacccgttct ctcaaccaga
    32581 gagacaaaac cagaattaag gctccagctc ctgctatcaa catcccataa aggaagatgg
    32641 tcaggaaggt ttggaaagtt gcaactgagt ctttgatttg ttcaaaagcc ttgttttcct
    32701 tttcgacttg gtagccttga ttttccaagg ccaagttttc tacctgcttc atgagtccgt
    32761 ccatttcctt aggattttct acatagaagc gtgctgcact gacttgagct tcactattgc
    32821 ccaaaagggt ttggctactt tcataatctg taaagacttg attttcactg aagtcagaag
    32881 acaagcctgt gaatttctct tgttttttac cagaaaagat gccgataatc tcaaactcta
    32941 ctgtttgtcc ttttccagat tcagactgac cagcatccaa gccaatcttg tcatgaagtg
    33001 aaagaccgtt cttcttagcc aattcttcgt ggataaggat tttcttggaa tccccttttt
    33061 gaaggtgtcg cccttctttt agattgaaag ccgaactggt aaaggttaca tccttggatg
    33121 aatcctcaag agccgttaag ctaaccaagt tattgtctgc agctgataaa tcatcacgct
    33181 ccacgctctg ctcgccagtc actgcttcct tgtcttttag ttttgcgacc gtctcaagtt
    33241 caggagagac attttccagc cccttaatct tgcttacaga tgctaggtct gacaacttga
    33301 atgtctgacc attctctatc ttcttaatag aaaaagatgt attgagtgat ttataaagat
    33361 tgctttctac tgttttgttg gacttcatca gagtcaaaca ggctgaaatt ccggccaata
    33421 agaccaataa aatcagaaat aaaataaaac ttctcagtcg ctttctgctg acataagccc
    33481 aagatctttg gattggattc atttgtcacc tccatatttg taagactatt ataaaaccca
    33541 aatatgaaat gtttatgaaa tacgaaaaaa aaaa
//
LOCUS       DAVLDI010000020        32692 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLDI010000020 DAVLDI010000000
VERSION     DAVLDI010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.020"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(381..1361)
                     /locus_tag="VXD01_000959"
     CDS             complement(381..1361)
                     /locus_tag="VXD01_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV0601384.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTLEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1687..1890)
                     /locus_tag="VXD01_000960"
     CDS             complement(1687..1890)
                     /locus_tag="VXD01_000960"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601385.1"
                     /translation="MKIKEQTRKLTAGCSKHCFEVVDETDEVSSKHGFEVVDETDEVS
                     SKHRFEVADRTDEVSNIYTVRRR"
     gene            complement(1918..3933)
                     /gene="recG"
                     /locus_tag="VXD01_000961"
     CDS             complement(1918..3933)
                     /gene="recG"
                     /locus_tag="VXD01_000961"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV0601386.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLNGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3952..5055)
                     /locus_tag="VXD01_000962"
     CDS             complement(3952..5055)
                     /locus_tag="VXD01_000962"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV0601387.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(5045..5413)
                     /locus_tag="VXD01_000963"
     CDS             complement(5045..5413)
                     /locus_tag="VXD01_000963"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV0601388.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5452..6483)
                     /locus_tag="VXD01_000964"
     CDS             complement(5452..6483)
                     /locus_tag="VXD01_000964"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0601389.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6485..7516)
                     /locus_tag="VXD01_000965"
     CDS             complement(6485..7516)
                     /locus_tag="VXD01_000965"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV0601390.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7597..10110)
                     /gene="secA"
                     /locus_tag="VXD01_000966"
     CDS             complement(7597..10110)
                     /gene="secA"
                     /locus_tag="VXD01_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV0601391.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10256..10543)
                     /locus_tag="VXD01_000967"
     CDS             complement(10256..10543)
                     /locus_tag="VXD01_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601392.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(10554..11204)
                     /locus_tag="VXD01_000968"
     CDS             complement(10554..11204)
                     /locus_tag="VXD01_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0601393.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            complement(11208..11543)
                     /locus_tag="VXD01_000969"
                     /pseudo
     CDS             complement(11208..11543)
                     /locus_tag="VXD01_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11792..12142)
                     /locus_tag="VXD01_000970"
     CDS             complement(11792..12142)
                     /locus_tag="VXD01_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601394.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(12282..12617)
                     /locus_tag="VXD01_000971"
     CDS             complement(12282..12617)
                     /locus_tag="VXD01_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601395.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWIYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(12708..14018)
                     /gene="der"
                     /locus_tag="VXD01_000972"
     CDS             complement(12708..14018)
                     /gene="der"
                     /locus_tag="VXD01_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV0601396.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPGMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14032..14745)
                     /locus_tag="VXD01_000973"
     CDS             complement(14032..14745)
                     /locus_tag="VXD01_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV0601397.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(14742..15638)
                     /gene="dnaI"
                     /locus_tag="VXD01_000974"
     CDS             complement(14742..15638)
                     /gene="dnaI"
                     /locus_tag="VXD01_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV0601398.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(15639..16808)
                     /locus_tag="VXD01_000975"
     CDS             complement(15639..16808)
                     /locus_tag="VXD01_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV0601399.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSPKETTIIKEAKSKTALQFLAEIKQTRKGTTTQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(16809..17282)
                     /gene="nrdR"
                     /locus_tag="VXD01_000976"
     CDS             complement(16809..17282)
                     /gene="nrdR"
                     /locus_tag="VXD01_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV0601400.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            17422..17787
                     /locus_tag="VXD01_000977"
     CDS             17422..17787
                     /locus_tag="VXD01_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0601401.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            17792..18487
                     /locus_tag="VXD01_000978"
     CDS             17792..18487
                     /locus_tag="VXD01_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601402.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            18504..19271
                     /locus_tag="VXD01_000979"
     CDS             18504..19271
                     /locus_tag="VXD01_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601403.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(19624..20823)
                     /locus_tag="VXD01_000980"
     CDS             complement(19624..20823)
                     /locus_tag="VXD01_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0601404.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGILNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEV
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILVHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(20820..21713)
                     /locus_tag="VXD01_000981"
     CDS             complement(20820..21713)
                     /locus_tag="VXD01_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601405.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            21830..21910
                     /locus_tag="VXD01_000982"
                     /pseudo
     CDS             21830..21910
                     /locus_tag="VXD01_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            22420..22608
                     /locus_tag="VXD01_000983"
                     /pseudo
     CDS             22420..22608
                     /locus_tag="VXD01_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23023..23640
                     /locus_tag="VXD01_000984"
     CDS             23023..23640
                     /locus_tag="VXD01_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV0601406.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(23960..24847)
                     /locus_tag="VXD01_000985"
     CDS             complement(23960..24847)
                     /locus_tag="VXD01_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0601407.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(24996..26879)
                     /locus_tag="VXD01_000986"
     CDS             complement(24996..26879)
                     /locus_tag="VXD01_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0601408.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     SQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            27256..28710
                     /locus_tag="VXD01_000987"
     CDS             27256..28710
                     /locus_tag="VXD01_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0601409.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMKFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAINNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRVLAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNSQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            28691..29656
                     /locus_tag="VXD01_000988"
     CDS             28691..29656
                     /locus_tag="VXD01_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0601410.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(29691..30965)
                     /locus_tag="VXD01_000989"
     CDS             complement(29691..30965)
                     /locus_tag="VXD01_000989"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV0601411.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGASDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(30965..32137)
                     /locus_tag="VXD01_000990"
     CDS             complement(30965..32137)
                     /locus_tag="VXD01_000990"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV0601412.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(32268..32516)
                     /locus_tag="VXD01_000991"
     CDS             complement(32268..32516)
                     /locus_tag="VXD01_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601413.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(32584..>32692)
                     /locus_tag="VXD01_000992"
     CDS             complement(32584..>32692)
                     /locus_tag="VXD01_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEV0601414.1"
                     /translation="VKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
BASE COUNT         9477 a         7371 c         6178 g         9666 t
ORIGIN      
        1 aacatatata cggcaaggcg aagctgacgt ggtttgaaga gatttttgaa aagtattaac
       61 acctacagac aagcctaacg atagcaagaa ctaccctact cgataggtat cggcttttgc
      121 tttctgaaaa aaattatttt aagcaatttg acaaatctag caacaaaaaa ttctataaat
      181 acaatagatt gaaactagaa tagtacacat ctacttctaa aacattgtta gaaatcgatt
      241 tgactgtcct gatcgatttg tcctgttctt gtttcatttt actatatttc catgataaaa
      301 cgcatagtat caagttctct taatcccctg atactatgcg tgtttgtaat ttttaagatt
      361 ttgtgcttag agtcgactcc ttattttaga tatttaaaag gaatctcact tccacagagc
      421 cagttgtaga cttggtcatt aacaaataca ttcatggctt cgtgagcata ctcaggcatg
      481 atacgatagg ttttatcgca ggtcagacga ttataaatcg caaactgggt aatgggatag
      541 caaacatcgt cgtccaagcc cgtaatcatc ttaacctcac cttggatacg atgggcaaga
      601 tttttgacat cgatataggc aagggtcgcc atgatttcct cctctgtttc atggaagggg
      661 tcgtgaaact tgaaataacg gaaaagttcg tcgtaagcct cgctagtatt accaatctca
      721 atcacccgtc tgaagtctga caagaaggga taaatggcaa ctgttttctg aattcgagga
      781 ttgagcgctg ctgcaactag agctagagcc cctccttgtg aggcaccata gctagaaaga
      841 cgcttctcat caacctgaga cagactagca acaatttcga ccaactggta aatatccaga
      901 taaacatcct tataaaagag gtggtcccga ccttccatag caccacggat aatatgcccc
      961 ttaaccgtat ttcctaaagg agaacgcaag ccgtcttgtg agtaacctga ctggccccgc
     1021 acatccatgg aaacaacacc gtaaccagct acggtgaagc ccagcatgtc ggcccagtcc
     1081 cagccacgtc ccatataacc atgaaaatgg aagattagtg gaaccttctc ctcactcttt
     1141 ggaagaacaa tgcgtgcata gacctttcct tccttgcttc cttccaatgt taactcatag
     1201 cacttgactt gaggaatgtg gaaatctctt tcctccaagt ggtaggatgg aagcgtggaa
     1261 acatttttca cttccccatc ccagaaagca tcaaagtctt ccggaacctc atcccttcct
     1321 ctataggtct taatttcttc tagcaaagct ggatttttca tagcatgctc cttttatttt
     1381 gtaatcgtta ccacaactgt agcatatcta tgtaatcaat gcaagaaaga aggataaata
     1441 gaaagtgaat ttagattctt tacttttagg atgatgggct gaaagtagtt ttagaaacga
     1501 aaaagagcat ttcgctctct cttctgttta tactagtttt ttgcttcctt cttttggaaa
     1561 gtggtttggt aatttacttt aatcgttact gtcatatgag agtcctcgtt tctttttgat
     1621 gactttagta taagagccaa acctaaaaac tagcttaata ctcttcgaaa atctcttcaa
     1681 accacgtcag cgtcgcctta ccgtatatat gttactgact tcgtcagttc tatctgccac
     1741 ctcaaaacgg tgttttgagc tgacttcgtc agtttcatct acaacctcaa aaccatgttt
     1801 tgagctgact tcgtcagttt catccacaac ctcaaaacag tgttttgagc aacctgcggt
     1861 tagcttccta gtttgctctt tgattttcat tgagtataag ttttccttag agaaagctta
     1921 atccagatgt tctttctttt ccagatgaag ggcaatcatg cgccactctg gatcttcttg
     1981 ccaagcttct atagaactaa tgtagctagc aacctttctt gcttcttcta aaatcggaaa
     2041 atcttcgata atatcagcca cttggaactc tggaagtcct gactgtctgg ttccaaaaat
     2101 ctcaccagaa ccacgcattt tcaaatcttc ctccgcaagg acaaatccat tggtcgtttc
     2161 tgtcatgatg cgcatgcggt ctttcccaga atccgtcttg ggattggcaa cgagaacagc
     2221 gtaggactgc ttgtcccccc gaccgacacg acctctaagc tggtgaagtt gactgagacc
     2281 gaagcgatcg gcatccatga taatcatgac agtcgcattg ggaacgttga ccccaacctc
     2341 aataaccgtc gtcgaaacca gaatatccgt ctttctctcc ttgaaatcct gcatgatctg
     2401 gtctttttcg tcactcttca tcctaccatg tagaagagcc acctctgcct tgcctgcaaa
     2461 atgagtcgtc aactcctctg ataaggcaat ggcatttttc aaatctagag cttctgattc
     2521 ttcaatcaaa ggagagatga cataggcttg ggaacctttt tgaatttccc cctctaacca
     2581 agtcaagacc tgaggtagtt gctcatgttt gatccagcgc gtcacaatag gcttccgacc
     2641 tgctggcatc tggtcgataa tggaaacatc catatctcca aaggctgtga tggcaagcgt
     2701 ccgtggaatg ggagtcgccg tcatcatgag gacatctgga ttgtcacctt tttcccgtaa
     2761 aatacgcctt tgccctacac caaaacggtg ctgctcatcg ataataatca aaccaagacg
     2821 agcatactcc accccatctt gtatcagagc gtgagttcct ataatcaaat cagcctcacc
     2881 cttggcaatg gtctccaaga cttctctctt ttctgcagct ttcaaggaac ctgtcaagag
     2941 agccagtttc aaattgggaa aaaggttctg taaactctca aagtgttgct ctgcgaggat
     3001 ttctgttggt accattaggg cagcctgata acctgctgtc actgccgcaa acatggccaa
     3061 gccagcgact accgtttttc cactccccac atccccttgt aggagacgat tcatgtggtg
     3121 gtcggacttc atatcagtta aaatttcctg caaactcttt tcctgagctt gggtcagggc
     3181 aaaaggaaga cttgctttaa ctgctgtcac tttttcctga gaccaatcca gaaccagacc
     3241 acttccctga actctatttt cagacttgag catctgcagc tgcatttgga aataaaagag
     3301 ttcctcaaac tttatacggc gaagagcctg cttgtattct gccaaatcct ttggaaaatg
     3361 catagctcgg actgcctgac aacgggacat gagtttgtat ttgtctagta aagactgggg
     3421 cagattttct tctatcaaga ggtccagtcc ctgatcaaaa gccgtcttga tgaccttaac
     3481 cagactggcc tgactgattc cctgagccag acgataaaca ggctggaggt catcttctac
     3541 ctgagccaga accttcatcc cattcagact agccttagcg cggtcccatt ttccaaagac
     3601 agcaagggtt gctcccaact ctattttatc agccagatag ggctggttaa agaaattcac
     3661 cgcaaaaacg acctctccct gcttgagact aaaacgcagg cgattgcgct tgaaaccata
     3721 atactggaca ctagcaggag tcactacctg accagaaaga actgccttct caccgtcttc
     3781 cagctccagc acctgcttgg ttttgaagtc ttcataacgg aaaggaaagt agagcaagag
     3841 atcttgcaag ttttcaattc ctagtttggc atatttttct gctgactttg gtcccacacc
     3901 aggcaagaca tgcaagggtt gatgtagatt catgctccac tcctttcttt tctaataata
     3961 ttctctcgga atacggtcgc tgaggaggca aaccacctca tagttaatgg ttacgcggta
     4021 ggtcgctacc tgagttgcag tgatttcctt atccccattg gagccaatca aggttacctt
     4081 ggttccgagt gggtaaggct taggcaatcg aatagtgatt tggtccatcg aaaccctgcc
     4141 gacaattggg caagcttggc catctaccaa gacagagaaa ttttgcatgt ctcttgtcca
     4201 tccatctgca tacccgattg gtacggtcgc gatgacttgc tcgctatccg cttgataagt
     4261 tgctccatag cccatgcaag ctccagctgg aactgtcttg acatgaacca gagcagactc
     4321 caaggtcaag gccggtatca aatcataagg caaatccaag accgctccac ttggattgag
     4381 gccatacatg gcatctccca tacgaaccgc attgaaaata gtctctacat gccaaagagt
     4441 cgttgcagaa ttgctagcat gaaccagctc tggaacttcc ttcatactag ctaaaatagt
     4501 tttaaaccgt tctaactggg cattaaaata gtcatctgat tcctcatcag cagtagcaaa
     4561 gtgggtaaag attccttcaa cacgaacacc gtgttgttgg agcaaatctt gagcctgctc
     4621 aacctcactg gcctctctaa aaccaatccg tcccatccct gaatcaatct tgaggtggac
     4681 tgtcaatcca gttaggtcca cttccttatc taagagtgct tgaatccact ccagtccagc
     4741 cactgtcaag gtgaagtcat attctttagc tagagcaaca gcttcgattt cagaaactcc
     4801 taaaatgagg attggcttgc tgagtccagc ttgtctgagt tcaatggctt catcgatatt
     4861 ggaaacgcaa aagccatcaa catcatcttg aattgccttg gcaacggcaa cagctccatg
     4921 accataagca ttggccttga ccacagccaa cttgagcgtt ccttgaggga tatgagcccc
     4981 catttgctga atattttgtc gaatagctcc cagatgaatc agagccttgg ttggtctatg
     5041 tggactagct ttcatgattt tcctccaaaa tgacactggc tgtcacaaac tgatcggtgt
     5101 ggctgataga cagccaaatc tttcctgaaa atggtgcctg actaaaataa ggcgccccac
     5161 gttcattgtt caagacttcc aaatcctgaa aaccgagctt gctaatgccc gttcccatag
     5221 ccttggaaaa ggcctcctta gccgaccagc gaccagctaa atattctatt tgcctgcgtc
     5281 ctttgagact ggtgaagcgc tccatttcct gagcggtcag tacacgctta gcaaatcctt
     5341 catgtcgtgt aactgcgctt tctatcgaag ccaattcttc gatgtcaatt ccgtgtccaa
     5401 ctatcattct catcaaaagg agttgagatt ccccaactcc atccttttca cttattttgt
     5461 caaggtaaca taaatctctt ctaccaaggc ctctgtattt tcccaaccta ggcaagggtc
     5521 agtaatagag caaccaaaga tctctggttg gttttgacga ccatctgcta ggtaagattc
     5581 aatcataaat cctcgaaccg tctttttaat tttctcattc caatcacgat tctgcaaggt
     5641 ctggcgaaca attcgaatct gctccatata ttgcttgcct gagttatcat ggttggtgtc
     5701 aatgaggata aaaggatttt caagtcccat ggtttcatag cgttcaatgg cttggagtag
     5761 gttttcatag tagtaattcg gcatataatt gccatactcg ttgactgctc cacggaggat
     5821 aacatgggcc aaaggattac ctgatgtctc aacttcctgc ccatgataaa ggaaggtttg
     5881 cttgttttga gcagcataga tggcgttaaa cataacaccc aaatttcctg aggttggatt
     5941 tttcatccct actggtgcat caatcccaga agccacaaag cggtgctctt ggtcttccac
     6001 agaacgagct ccaacggcat ggtagctgac caagtcatcc accaagatca gatttgacgg
     6061 ataaagcatc tcatctgccg ttgtcaaacc agtctctgta atcacgcggt agtgcaactg
     6121 gcgcacagcc tgcaagccgt taatcaggct tggagcctta gaagtatctg gctggtgaac
     6181 caatccttta tagccgtctc cattggtacg aggcttagca gtatacacgc gcatgaccat
     6241 gaaaatcttg tccgctacct tcttttgcaa ggcggataaa cggcgagcat attccaagac
     6301 cgcctcttca ttatcagaag agcaaggacc aatcaccaag agaatacggt catcttcccc
     6361 tgaaataata tctgccaatt ccctgtcacg gctttccttg agtctcaagg cttctgcaga
     6421 caattgggtt tcagccttga tgacttccat atcgatttct tgaccttttt caataaatgc
     6481 catcttattc tcctaacgtt ttgtaaattt ctctgacaag agcttctgtg ttatcccaac
     6541 ccaggcaagg gtctgtgata gacttaccaa atacttctgg ctcattttgt cgaccatctt
     6601 ccagataaga ctcaatcata aaaccacgaa cgaactgctt aattttttca ttccaagcac
     6661 ggttaatcaa ggtctggcgg acaattcgga tctgttcaat atactgctta ccagaattgt
     6721 catgattggt atcaatgatg ataaaaggat tttccaagcc cattttctca tactgggcaa
     6781 tggtatcaat taaattgtca taatagtagt tgggaatatt ttttccatac tcattaagag
     6841 caccacgaag aatagcgtgt gaaagcgggt tcccagttgt ttctacttct tttcctaaga
     6901 aaaggaaact ttgtttgttt tgagcagcat aaatcccatt aaacatgaca ttgagatttc
     6961 cagaggttgg atttttaaaa ccagtagaaa atcctgcccc acttgccaca aagcggtgtt
     7021 gctggtcttc aactgaacgg gcaccaactg ccatgtaaga aatcaaatca tctacaagcg
     7081 gaaggttttc aggataaagc atttcatcag cagttgtcat ccctgtttct gtgatgacac
     7141 gatagtgaag atggcgaacg gctttgattc cattgataag actaggcgct tctgtcgcgt
     7201 taggctggtg aatcaagcct ttatagccat ctccgttggt acggggtttg gcagtataaa
     7261 cacgcataac cataaagata cgatctgcca cttcttcttg taggactgcc aaacgcttag
     7321 cgtattcaag gacagcttct tcgttatcag atgagcatgg cccgattacc aagagaattc
     7381 gctggtcttc tccacgtata atggcttcta gctcttgatc tctctgtgat ttcctctcca
     7441 aagcctgacc ttctaatttt gacaaggcac gaacttcttc tatatttatt ttagagcttt
     7501 ttgctgtaaa taccataact catctcctta taaagcaaac ggatacccag taaaaattta
     7561 cttttcacaa gatatccgcc tctaaactat ctcattttat tgtcttttac cgtgacagtt
     7621 tttaaatttc ttaccagaac cacatgggca aagttcattg cgtccaatct ggctcaaatc
     7681 caaatcttct ggcatacttg cttggtgagc agcgatattg cgagtcgctg ttgtactgat
     7741 atgacgttct gcctgtggtc tttcttgttc atgaatttgt gctttcatca tcaagcgtgt
     7801 cacatcaaac tcaatcgaac caatcatatc attaaacata cggaaacctt ctgcctgata
     7861 ctcaacaaca gggttgttct gagcatagcc acgaagtcca accgcgttac gcaattgatc
     7921 aagggcatcg atatgatctg tccacttgtt atccaccact cgtagaatca aaactttttg
     7981 gaattcttta actgcttctt catcgcgtag ttttgaaacc tgactatcgt aaaccttcaa
     8041 ggcacgttgg aaaagctctt ccttgatggc cttatcagac aagcctgaca agtcttccat
     8101 cgtaatagaa tcttcaggaa gcaagttgta cttagcaaag ttcaaaattg cctctagttt
     8161 ttcatcttgt ttggcacgcg catgaccatc aacgacacgt tcaatcgtgc gcttaatcat
     8221 agactgaatt tcaggtgcca agtcacgatc tgcagtgatg acatcgtaac gttgagcata
     8281 gataatctca cgttgttcac gcatgacatc atcgtattga aggacttgtt tacgggtatc
     8341 gtagttattt ccttcgacac gtttctgagc tgcttcaacc tgacgcgtca acatgcgaga
     8401 ctcaatcgcc tcttcagaca tgttcaagcg ttcaaagatt cccttcaagc gttcagaacc
     8461 aaaacgtttc atcaaatcat cttcaagaga taggtagaat tgtgactcac ctggatctcc
     8521 ttgacgacct gaacgtccac gaagctggtt atcgatacga cgactttcat gacgttctgt
     8581 accaataaca caaagtcctc caagttcacg aacaccttca ccaagcttga tgtcggtacc
     8641 acgacccgcc atgttggttg cgatggtaac ggcaccacgt tgaccagcat tcatgatgat
     8701 ttgggcttct ctatagtggt ttttggcatt caagacttcg tgaggaacac cagctgcaac
     8761 caatttctta gaaatgtagt cactagtttc aaccgctact gtaccaacca agacaggttg
     8821 acccttttgg taacgagcct taacgtcttc gacaaccgct ttaaacttag attctatact
     8881 tgcataaaga aggtctgagt ggtcaatacg ttgaacagga cggtttgttg ggattggaat
     8941 aacacgaatg ttgtagattt cacggaattc ttcttcctca gtcttacctg tacccgtcat
     9001 accagacaat ttcttgtaca tacggaaaag gttttggtac gtgattgagg cagatgtctt
     9061 ggtttcatcc tggattggca caccttcttt ggcttcaata gcttggtgca atccatcaga
     9121 ataacgacga ccttccatgg tacgacctgt aaattggtcg acaatcaaga tttcttgctc
     9181 ttcgctcacc acatagtcaa tatcgagaag catgatgtag ttggcacgaa gggcgttatc
     9241 gataaagtgg gtcaaagcca cgttttcgat gtcatagagg ttttcaagtt tgaagtagct
     9301 ttcagccctg tcaatccctg aatcagacaa accaatagtc ttagactgca catcgatgat
     9361 gtagtcatct ttgttcaaag attttacata gtggtctgcc atgtgataca actgactggt
     9421 ttcaaccgca ttggcacctg atacaatcaa aggtgtacga gcctcgtcaa tcaagataga
     9481 gtcaacctca tcgaccaagg catagttaag cggacgttgt accatgtttt cagcgcgaac
     9541 gaccatgttg tcacgaaggt agtcaaatcc gatttctgag ttagttgagt aagtaatatc
     9601 acactcatag gcttcttttt tctccattgg agatttggta gccaagttaa tccctactga
     9661 caaaccaagc caagagtaca attcacccat ctcagtcgcg tcacgttctg acaggtattc
     9721 attaaccgta actacgtgaa cccctttacc tgaaagggca ttgaggtata ccggcatggt
     9781 cgcagtcaag gttttccctt cccctgtacg catctctggc acgtcaccat ggtgaagaac
     9841 aatccccccc atgacctgaa ccttataagg gaagagacct aggacacgtt tggcaccttc
     9901 acggacaacc gcaaatgctt cgtaaagcaa tgaatccagt gattctccat tttgataacg
     9961 ttccttaaat tcaactgttt ttgcttttag ttggtcgtca gtcaaagcag ccatttggtc
    10021 ttcgtatttg aaaaccttgt cagccatctt ttccagacga cggatttctc ctttatcatt
    10081 ttcgataatt gtttttaaaa tattagccat gtttttcctt actttaaatt ccgaatattt
    10141 tagaatgttc ctttaatttt agcacaatta ctgattattt tcaaggaaga atccccattt
    10201 tgaaaaggaa aaagaggtta gttttcaagc taacctctcc gacttttatg actgtttaat
    10261 tgccaaaaat cggcaaaatg gcaaatgtga taaataagtt aatccaaaga gaaagacagc
    10321 aaatcagtcc aaaaacaaag agactgactt tcttggacag caaggccatc aaaatggaca
    10381 gaattccaaa aactagcaag actttctgta tgatgaagat gtcaatcctt acccccagaa
    10441 tcgctctatc ccaagggata aagaagaaag acagccagat cagcagaact aaaccaatat
    10501 aaaccttgga atagcgtgta ataaatgatt ttagatgtgc cataagccat ctcctaggat
    10561 tgtatatcct ttacatattg tatatgtcca ttttcgacaa ctaatacatc tgtacaaagg
    10621 tctgaaatat cttccgatat gtgcgacgtc aggataacca gaccattttc ttttttcagg
    10681 taagataaaa tgacctgttt ggttaacctc acacttttct catccaaagc attcataggt
    10741 tcatcgagaa agagtataga aggagaggaa ataaaggctt gaatcaaggc cattttttgc
    10801 tttgttccca aggataaatg acggtattca acatcttcaa attcctgtaa atcatagtat
    10861 tgaatccaat aggcaattct tttttccgta actttagatg aaaaatacct taacagttcc
    10921 aaattttctc tcagggataa atgagataaa aactcgactt tttcaattaa aattcctgca
    10981 tcctgaatat aatgattttt taccccgtaa actttaccat cttgaagaac ttttcctttg
    11041 tcaagcttaa tataaccagc aagtatcttt aaaagaaccg tcttgccaga tccattatca
    11101 cctttaagtc cataaatttt tcctgattga aacaccaaat tcaactgatt taaaataggt
    11161 cttttcccat aaattttctg tccatttata atttcaagtc tcatcgttta tcctttctta
    11221 aatttctctt ccaagcgact aagaatcaac ataactaata agcttaagag tactaaatac
    11281 actgttacaa tatgatccat catccattct tgtcccacaa atgccaaaaa atagagaaaa
    11341 aaagaaaaac cagcgcccgc actaatcagt gctatcagat aagacagtag taagtacaac
    11401 atcattaact gagcaagtaa aaagaaaagt gcgactgttt tgaaatgaat tcctagcgga
    11461 agtaaaccaa gaaaccagac aaacaaatct tgagtaaaaa atttagaaat gacaaccaat
    11521 cgtttccttg tataatcgaa aaagaaatta atgatttttc aaacctataa tttgtaataa
    11581 ctctcatcat tttattatag tagattgtaa tagaatgtga acgaatcaat taggggatct
    11641 aaagcatttt ataccaatgt tttataagtt gtattgtatt attccatatt caatccacta
    11701 tacaagatga atatttctct caagtttcat aatcaaaata aaaatgactg tatctatagc
    11761 tccataaaca aatcatagat acagtcattt tttagttcct acaccttcct ttatgcacac
    11821 ctttagactt ccctagttcc cgtctcaagt caagcatttt tttgaaacag atatagtcta
    11881 accagtcact agcaaaagcg ataagtagta ataatagcca aataccccat aacttgatat
    11941 ctgtcaaatt tctcaagacg atattgaaaa acagaactga aaaaactgtc caagcaaggc
    12001 taaaaagagc atagagggtg atgtaaatcc agtaaaaata gtaaaaaatt gggaaaaatt
    12061 tactttctct attatccttg tcaatccagc tgaaaaagta aaaacagggt aataagatta
    12121 tcattttaaa caagtgttcc atcacaagcc tcctttttta aattgttttc tttagtttcg
    12181 ttctattaaa tgttattacc aatataaacc ttggaatagc gtgtaataaa tgattttaga
    12241 ggtaccataa gccacctcct acaaatagaa accgatataa atcaatgcct tccaccctta
    12301 gacttcccta gttcctgtct caagcgaaac atttctttga aacaggaata agttaaccaa
    12361 ttcataccaa tagctagcag aataaaaaga aaccaaatgc cccataactt gatatctgtc
    12421 acatttctca agacggtatt gaaaaacaga actgaaacaa ctgtccaagc aaggctaaaa
    12481 agagaataga aggggatgta aatccagtaa aaataataaa aaattggaaa aaacttacta
    12541 tttctgttgg ccttttcaat ccagttatca aaataaaagt acggtgctaa aagtaagaat
    12601 ttaaacaaat gttccatcac cgacatcccc ctccttcttt tgatagcgtt ttctattatt
    12661 ttattatatc aaaaaaatcc ggaactgtca ttccagattc tactttttta tttgcgtttt
    12721 cttgcgatga gatgaatcgg tgttccctca aaaacaaagg ccttgcggat ttgattttcc
    12781 aagaaacgta ggtaagaaaa gtgcatgagt tcttcttcgt tgacaaagat aacaaaggtt
    12841 ggtggtttgg ttgccacttg ggtcgcatag aaaatcttga gacgttttcc tttgtctgtc
    12901 ggtgttgggt tgatggcaat ggcatccatg atgacatcgt tcaagacagc tgatggaata
    12961 cgtgtatttt gactttcgct gatttgctta atcatcccag gaagtttgtg gagacgttgc
    13021 ttggttaaag ctgatacaaa gataatcggt gcgtaaggca ggtattggaa ctgctcacgg
    13081 atatcttctt cccagttttt catagtgtgg ttatcttttt caagcgtatc ccacttgttg
    13141 accacgataa tcatcccttt accagcttca tgagcaaatc cagcgatacg cttgtcgtat
    13201 tcacgaatcc cctcttccgc attgatgacc attaagacca catctgaacg gtcaatagca
    13261 cgcatggcac gcatgacaga gtacttctca gtattttcat aaaccttacc agacttacgc
    13321 ataccagccg tatcaatcat ggtaaactct tgaccatctg tatctgtaaa gtgggtatca
    13381 atagcgtcac gagttgttcc agcaacagga ctggcaataa cacggtcttc gcccaagata
    13441 gcattgatca agcttgattt tccaacgtta ggacgaccaa tcaggctaaa cttaatgaca
    13501 tctggatttt cttcctcata ttcatttgga agattttcta cgatagcatc tagtacatcc
    13561 cctgtaccga ttccatggac agatgagata ggcagtggtt cacccaaacc gagagcatag
    13621 aaatcataga tatcatttct catctcaggg ttgtccacct tgttgactgc gaggataact
    13681 ggtttgtggg tcttataaag cttacgggct acgtattcgt ctgcatcggt aattccttcc
    13741 ttaccggaca cgacaaagac gataacatct gcttcttcca tggcaatttc tgcctggtgc
    13801 ttgatttgtt ccatgaaagg agcatcgaca tcatcaattc ctcctgtatc aatcatgcta
    13861 aaagaacgat tgagccactc acccgttgca taaatacggt cacgtgtcac tccttcgaca
    13921 tcttctacaa tggagattcg ctcaccagcg atccgattaa atagggttga tttcccaaca
    13981 ttgggacgtc ctacaatggc aatagttggt agggccataa tttctcactt tctacaataa
    14041 tttcttctgt tcaagatttt ttctagttga gcttggttca gcttgaccaa actgttctgc
    14101 taggcgctga ctccagcttg tggtcgcacg cgccccagca tagtcagcct gaacacggtc
    14161 ataagcttgg attgcctcag ttgactgttc ttggtattct tcctcaaaga caacattctc
    14221 tagtggcagt ctcggtttca tatcatgatg ttgatttggc acacccagtg ccatcccaaa
    14281 gacagaatag gtgtagtcag gcaggttaaa gagctctgcc acttcttcag acttgtatcg
    14341 aaccaaaccg ataatcacac caccatagcc caagctttca gctgccaaca aggcgttttg
    14401 tccagcaaga gctgcatcga ccgaactaat caagagacct tccacacctt ggggttggaa
    14461 ggtgtcggta tgaagtcggg ctcccttttc tgctcggttc aaatctccga caaagagaag
    14521 gaaaacagca gactggcgaa tggcttcttg aggtaccaat tcatacaagg catctttctt
    14581 ctcttgactt cgtaccacaa tcacagagta ggattggaaa ttcttccaag atgatgccat
    14641 ctgggctgct gtcaaaatct catttaagtc tacttgggga atttcttgct ctttaaacct
    14701 gcgcactgaa gtatgagcct tcatcaattt aatggtttct gtcatcgacg gtttactcct
    14761 tctaaacgag tctcctcagc caaataacgg atgcgttcca tgacccgtct ggcttcccag
    14821 gtttcgtcat ttccattttt ccctttagcg aaatgcttct ccaaatcttc aaagttgaag
    14881 ttagaggtga aaaaggtcgg taaattttcc tgcatccgat attggagaat gacctgtagg
    14941 atttcatcac gcacccaagc ggtggattgc tcggcaccaa tatcatctaa aatcaggact
    15001 tcagaaagct taatctcatc cactaaggtc ttaacattgc catcaccaat agcatttttg
    15061 acatcaatga caaagctagg atagtggagg agagtggatg atacaccacg tttttctgat
    15121 aaatcatgag ctagggcagc caccatgaaa cttttaccca caccaaagtc tccatacaag
    15181 taaagacctt ttcgaatagc tggatattgc tccacgaagg ctagtagctt ttcaaaaact
    15241 ggtaagcgcc ccaaatcatc caagtcaact tgagccaaac tagctttctt gagactggct
    15301 ggtagattga ttaacttgag acggttctta atagccgctt ctttttcagc cgcgattagc
    15361 tcaggagttt cttcatatga aacatctgca tagccatgat tcttaaccaa aatcggcttg
    15421 tagcctttgg caatataatc cgtatcccca cggagaaact tgtcacgctc ggtgatgtac
    15481 tgattaaact tggagatact gcgatttaat tcctctggag tcaaggattc ttgctggata
    15541 aaagccgcaa catcagggtc cttcatgatt ttctggacca aatcttgata ataaaaacgg
    15601 ctgggttgac gtttgagtac gtctccgaca ctttccatct aatctcctcc tttttctaat
    15661 cgagctaata gttcttgctt cttacgttct agttccagac gagtttcctc gctggtttca
    15721 ttcttatatt caggattact ccatttagga acattggttt ttactggggc agtctgattc
    15781 tgtttttgtg tttttgcttt ctgtcctcgc tcacggatgc gcaagactgc ctcttctgcc
    15841 gaatgaatct tttgataggc atagtcattg gctaccttca tggcatattt ctcattgata
    15901 tttgccgaat cgaccttatt aaaggtcaat aaaagaatga tattgatgac ttcgtccagc
    15961 aagcccaagc cagccatctg ttgcaagagt tctctttctg tttgggtagt ggttcccttg
    16021 cgtgtttgct tgatttctgc caagaactgc aaggcagttt tacttttagc ttccttgata
    16081 atggttgttt ccttaggact aaagtccgag gaaactggtt tttgagcaat tttttcccgc
    16141 atgcgtttgg ttgaaataac ctgggaaaca gctgttgact tggccaattg ataggtctca
    16201 aaccaagtcc acttcttctc ctcagcaata gcaaacaagt tcaagacatc agactgctca
    16261 tccgcaaaac gaagtccatc tcgagccatc agctgacgaa aatgatccaa gtcaaaatca
    16321 ttggccactt tcttcttgag accaaggtct tcttgactgc ctagttctgc caattctgga
    16381 aagacttgat tgagtgagac aggtatttct tcaccatcag cactttcaac tttcaaatcc
    16441 tccacagcag agtcgccaat ctttttctct aagagtctgc gataaacagg atgctccaag
    16501 aagtcttgac tagatagagg agcatggagg gctagctgat aaacatcccc cttttgatag
    16561 agggtcaaga gattaaaagc agataagatt ttcaatgatt ttatcagtct atccatccca
    16621 aagttgagat gattgaggat acttgaaaaa agatattcct ttctaccatt atcccaaaaa
    16681 ctgattgtat aaagataaag gctcagtgcc tcctgaccga taatcgggag gtagcactgt
    16741 accagagatg aggtatcttg cgacacccga ttattcttta gataagaaaa acggtcaatt
    16801 ggcttcattt atctttcctt tttcttttta gaggactggg tgatttgttg gagcaagctc
    16861 tctaactcac tgacatcctt aaaactacga tagacactag caaaacgtac ataggtaatc
    16921 tcgtccaatt cagccaactc ctccatgacg agtgaaccaa tgtcctcact ttgaatttca
    16981 ttttcatttc gaccacggag tttctgttcg atacgattga ctaccatgtt gatttcatca
    17041 cttgacacag gacgtttctg ggctgagcgg ataatcccat taaagatttt atctctggag
    17101 aattgttccc gtgtgccatc ttttttaaca accactaagg ttctttcttc tactcgttcg
    17161 taggttgtaa aacggtgttg gcactcgtcg cactctcgtc ttctacgaat ggtgttccct
    17221 tcttctgctt ggcgactatc gataacactt gacttggtag ccccacattt tggacaacgc
    17281 atcctttccc tccttatcgt tttcttttca ttataccatt ttttaagcga ttcccaaaac
    17341 aattcttctt tttgcttgac aagttttttg ttttgttgta ttatttaatt aagacaaaag
    17401 aataagagaa aggagactaa gatgtcctgg acatttgaca acaaaaaacc catctattta
    17461 cagattatgg agaaaatcaa gcttcagatt gtttcccata cactggaacc caatcaacaa
    17521 cttccaaccg tgagggagct agctagcgag gctggtgtca atcccaatac catccaaaga
    17581 gccttatcag accttgaacg agaaggattt gtctacagca agcgaacaac tggacgattt
    17641 gtgactaagg ataaggagct aatcgctcag tcacgcaaac aattatcaga agaagaattg
    17701 gaacacttcg tttcctccat gacccatttt ggctatgaaa aagaagaact accaggcgta
    17761 gtcagtgatt atattaaagg agtttaagcc tatgtcatta ctagcatttg aaaatgtatc
    17821 caaatcatat ggagcaacac cagcccttga aaatgtttct cttgacattc cagctggaaa
    17881 aattgtcggc cttcttgggc caaacggctc aggaaaaaca accctgatta aactaattaa
    17941 tggcctctta caaccagatc aaggacgtgt cctcatcaac gacatggacc caagcccagc
    18001 aaccaaggcc gttgtagctt atttgcctga tacgacctat ctcaatgagc aaatgaaggt
    18061 caaagaagcc ctaacctact tcaagacctt ctataaagat ttcaatcttg aacgcgctca
    18121 tcatctactt gcagacctgg gcattgatga aaatagtcgt ctcaagaaac tatcaaaagg
    18181 aaacaaagaa aaggttcaac tgattttggt tatgagccgt gatgctcgtc tctatgtttt
    18241 ggacgaaccc attggtgggg tggatccagc agcccgtgct tatatcctca ataccattat
    18301 caacaactac tcaccaactt ctaccgtttt gatttctacc cacttgattt ctgatatcga
    18361 gccaatcttg gatgaaattg tcttcctaaa agacggaaaa gtcgtccgtc aaggaaatgt
    18421 agatgatatt cgctacgagt caggtgaatc cattgaccaa ctcttccgtc aggaatttaa
    18481 ggcctaagca aaggagatta tttatgtttt ggaatttagt tcgctacgaa tttaaaaatg
    18541 ttaacaagtg gtatttagcc ctctacgcag ccgtgctagt cctttctgcc ctcatcggaa
    18601 tacagacaca aggctttaaa aatctacctt accaagaaag tcaggctact atgctacttt
    18661 ttctagccac agtctttggt ggcttgatgc ttacacttgc gatttcaacc attttcttga
    18721 ttattaaacg cttcaaaggt agtgtctacg accgacaagg ctatctgact ttgaccttgc
    18781 cagtttctga acaccatatc atcacagcca aactaatcgg tgcctttatc tggtcattga
    18841 ttagcaccgc tgtattggct ctaagtgctg ttattattct ggctttaaca gctccagaat
    18901 ggattcctct ttcttatgtg attacatttg tagaaacaca tctccctcag atctttctta
    18961 caggtatatc cttcctacta aataccattt caggaatcct ctgcatctac ctggctattt
    19021 ccattggaca gcttttcaat gaataccgta cagcactcgc tgttgcagcc tacattggta
    19081 tccaaatcgt cattggattt attgaacttt tcttcaatct tagttctaat ttctatgtca
    19141 attcactggt aggactcaat gaccatttct atatgggagc aggtatagcc attgttaaag
    19201 aactcatatt catagctatc ttttatctcg gaacctacta catcttgaga aataaggtta
    19261 atttgcttta aataattttt acctagatat gtaacatact catagaacaa aagaaaccag
    19321 gcaaaaagtc tttaaaatta gaaaacgcat agtatcaagt gttaaaaatc cttgatatta
    19381 tgcgtttttt gtgagctgac ttatttcctt tcactatatc gcaaaatgaa ataagaacgg
    19441 aacgatgaga ttttggaatt caaatcaatt tataagaatg ttttagaagt aatattatcc
    19501 tattccagat tcagttcact atacaattga gttttcaagc aacctgttta cataatgtgt
    19561 acataattag gttcgtgatt ccaccctttt cacctttaaa aacctcgctt tcgcaaggct
    19621 cttctattta taagataagg cacgtttaaa ggttttccaa atccctaaat catccgtttg
    19681 aagaacgaga ctagcataca tgcgtccgat aaatcctgtt gctaccaccg caaaaatcac
    19741 tgtaatagca agtgaaatcc atgcttctgc tccccccgca tagtcattaa tcgttcgaaa
    19801 cggcataaag aaggtcgaaa taaagggaat ataagaacca atcttcaaga ggagattgtc
    19861 accagctgca cctagagctg tcactccaaa aaaaccaccc ataatcaaaa tcatcaaagg
    19921 cgacaaggct ttccctgagt cctcaggacg agaaaccata gatcctagga aggctgccaa
    19981 gactacgtac atgaaaagac tgatcaaaat aaagagcaag gtattcagtg agatagcatc
    20041 tcccaagtga accaaaatac cagactgagc caagaatggc aaatctttaa agagcaaaac
    20101 ggcagccaga ccacctacaa catagatccc aatatgcgtt aaaatcacta gaaacagagc
    20161 catcatccgc gcatagaaat agtgacttgc ccttatgcta gaaaaaacga cttccataat
    20221 tttggtgcct ttttcactgg caacttcctg agctgttaca cccgcatagg taatcagaat
    20281 catataaaga aagaatccta aggcacctgc tgcaattgtt tgaataaact ttttattttc
    20341 cttgacttca tcaatctttt ctgtgaattg aattgtctgc gctaagcgtt tttcctgctc
    20401 ttgagacaag gaagcagttg aacgattaag ctgattttgc agttcattga gtatacctgt
    20461 aacctcaaat ttaattccat tttcaagcga tgtttcgcca tgataaactg cctttagaac
    20521 actatcttct tgatcaatgg tcaaataacc ttttaatttt tcttctttaa ttgcttcttt
    20581 ggcacttgct tcatctttat agtcgaagtt aacaccattt acattcttca gtccttctgc
    20641 tacagatggc actgttgtca ctactgccac tttattattt ttagccatag aagaaccttg
    20701 gagatgccca attcctacag agattcctaa aaagaggaac ggcgaaatca ccataaagaa
    20761 gaaactccat gactcgacat gtcgaagata ggtttccttg attacaaccc acatatttct
    20821 catacttcca ctcctgattc tagtttaaag atttcatcga tagttggcgc ttgttggtca
    20881 aatgttgcga tatattgacc ttgagtcaag attgggaaga gttcccttcc agcgctctca
    20941 tcctccaaaa tcaatttcca actgccttgt ttggtcaagc tcacctgttt gacatgagga
    21001 agattttcca attcttcctt gcttcgttca cttgaaacaa agagacgcgt tttcccgtat
    21061 tgattgcgga catcctgaac tggtccgtgc aagaccacac ggccatctcg gatcatcaga
    21121 atatcgtcac aaagttcctc aacattggtc atgacatggt cagaaaagat aatggttgct
    21181 ccgcgctctt tttcctgaaa aatgacttgt ttgagcaatt ctgtattaac tgggtccaat
    21241 ccactaaaag gctcatccaa gataatcagg tctggttcat gaatcagagt aataatgagc
    21301 tgaatcttct gctgatttcc ttttgacaga ctcttgattt tatctgtcag ctttcctttc
    21361 acttccaacc tcttcatcca ttgagggagt ttttctttga cttctttggc atccatgcct
    21421 tttagagtcg ccaagtagcg aacttgttca agaactgtca atttaggcat gagactgcgt
    21481 tcttcaggca gataaccaat ccgagcatag gtctcctgac gaatatcctg accatccaga
    21541 ccgatttctc cctgatattc taggaatttc aaaatactat ggaaaatcgt tgtttttcca
    21601 gcaccatttt ttccgactag tcccaaaata cgacctggtc gcgcttgaaa gtcaatacca
    21661 aacaaaactt gcttggatcc aaaacttttc tctagacttc ttacttctag catctttcac
    21721 ctccgaaatt tcttgcactc attatactcc tttttgatag cctttacaat gttttttgtc
    21781 catttttaga agactattgc tgtgtaaaat atggcctgga gcacttttat actcaatgaa
    21841 aagcaaagag caaactagaa agctagccgt aggctgctca aagtacagct ttgaggttgc
    21901 agataaaact gacgaagtca gctcaaaaca ctgttttgag gttgtggata gaactgacga
    21961 agtcagtaac tatacgtacg gcaaggcgaa gctgacgtgg tttgaagaga ttttcgaaga
    22021 gtattagtga taaatccatt atacagtagc aaacttaatt tataccttcc gctcctcaac
    22081 tgtctatttt taatcctgaa ttgttatttg agtaactcct ttttcctcat aaagttttct
    22141 tcctctaaaa cttctggaaa aaggcgaata gtttcagaca acatttttat aagaaacaag
    22201 ttcatctgtc atttcaagaa ggagtaatcc tttatctact aatggacgga acagaattca
    22261 accgcttgtc ccatatgttt tctaaggatt atatagtaaa atgaaataaa aacaggacaa
    22321 attgatcagg acagtcaaat tgatttctaa caatgtttta gaagtagatg tatactattc
    22381 tagtttcaat ctgctatatc tattatgcac atcactatag gatctaatga aaatcacaac
    22441 agactcattc atagatggtt acctcaggga actaagaaaa cgactacaaa ggaagtcgca
    22501 ttcatcgaaa agtggattaa caactatcct aaaaaatgct tgaactacaa gtcccccaga
    22561 gaagacttct ggatgactaa cttgaacttg aaatttagca ataattaatt caccatctaa
    22621 ctatatttag taattatttc agaactgatt aatattaaaa ttaactaaca attcaaagga
    22681 ttcatactag ccataaatta cgtccatcag agagagactc ttactacttt tagattttag
    22741 tctttctagc ttcagaatac atctaaactt taggaaaaat gactattcga aagcgcgaat
    22801 gcctcaaaat tatctcagat aagctattcg aaacttagaa tgcttttaaa tttatggaat
    22861 tgcgattatt cgaaacctag aatgcatata acctttagtt gacagaccta ttctaagtct
    22921 cgaagggcta tttactttct attccttatc aaaaaagact cattccccct ttctcctcca
    22981 aaatatggta tagtagaaat atactatcta tgaggagttt acatgtcaca ggataaacaa
    23041 atgaaagctg tttctcccct tctgcagcga gttatcaata tctcatcgat tgtcggtggg
    23101 gttgggagtt tgattttctg tatttgggct tatcaggctg ggattttaca atccaaggaa
    23161 accctctctg cctttatcca gcaggcaggc atctggggtc cacctctctt tatcttttta
    23221 cagattttac agactgtcgt ccctatcatt ccaggggcct tgacctcggt ggctggggtc
    23281 tttatctacg ggcacatcat cgggactatc tacaactata tcggcatcgt gattggctgt
    23341 gccattatct tttatctagt gcgcctatac ggagctgcct ttgtccagtc tgtcgtcagc
    23401 aagcgcacct acgacaagta catcggctgg ctagataagg gcaatcgttt tgaccgcttc
    23461 tttattttta tgatgatttg gcccattagc ccagctgact ttctctgtat gctggctgcc
    23521 ctgaccaaga tgagtttcaa gcgctacatg accatcatca ttctgaccaa accctttacc
    23581 ctcgtggttt atacctacgg tctgacctat attattgact ttttctggca aatgctttga
    23641 cacgtaaaaa atccgtttgg tttcccaagt ggatttttaa agcgtagatt aactatagct
    23701 tgatactaaa tatactttgg tatggaaatc atgcatattt ttcgatagtg aggcgaggac
    23761 ttacctagcc tttccgccgt gatagaaaca cctgaaatct aatggtttca ggtattcgga
    23821 aactttgaga cactaggctc aaagtttagg tatggaattt cgaagaaagt cgctaccgtc
    23881 cgtaatcact taaggaaagg ctcaaaaata ttgttttcaa ccacaaaatc cgtttggttt
    23941 cccaagcgga ttttgtgctt tattttgaaa cttcttttgc aagaacaaag ttcccaagtg
    24001 tggcagaacc atttcctgcg actgctggcg tcacgatata gtcacgcaca tctggtactg
    24061 gtaggtaacc attaagaaga gatgtaaatt tctcacggac acggtccagc atatgttgtt
    24121 gagccatgac ccctccacca aagacaatca cgtctgggcg gaaagtcact gtcgcattaa
    24181 ccgcagcttg agcgatatag taggcttgaa catcccaaac agggttgttg agttcaatag
    24241 tttccccacg tacacctgta cgagcttcca aacttggacc agctgcataa ccttctagac
    24301 atcccttatg gaaaggacaa acacccttaa actctttttc aatatccatt gggtgtctag
    24361 caacataata atgacccatt tcagggtgac ccacaccacc gataaactca ccacgttgga
    24421 tgacgcctgc accgatacct gtaccgattg tgtagtaaac caagttttcg atacgaccac
    24481 cagcattgtt acgggcaacc atttcaccgt aagcagagct gtttacgtct gttgtgaagt
    24541 acattggcac gtttagggcg cgacgaaggg caccaagcaa gtccacattt gcccagtttg
    24601 gttttggagt cgtcgtgata aagccataag tttttgagtt tttgtcaata tcaatcggcc
    24661 caaatgaacc aactgcaaga ccagcaaggt tatcgaattt tgagaagaac tcaatggttt
    24721 tatcgattgt ttcgattgga gttgttgttg gaaattgtgt tttttctaca acgttaaagt
    24781 tttcatcacc gacagcacag acaaactttg taccgcccgc ttccaagctt ccatataatt
    24841 ttgtcatgat aaacctcttg tttttatttt ctttattata gcatacttcg aaagtctaaa
    24901 tgtctctatt ttttagattt tcctctgtaa atcttactat ctaataaaaa cgaacaaaca
    24961 tgtcatttgt tcgttttcac attagagagg attgattaga ttttcacttc gatcacagca
    25021 tcccccttcg caactgaacc tgttgcgact ggagctactg aagcgtagtc agctgtattt
    25081 gtaacgataa ccattgttgt atcatcaagt ccagctgcag cgattttgtt tgagtcaaat
    25141 gttccaagaa catcgccagc tttcacctta ttaccttgag aaacttttgc ttcaaaaccg
    25201 tcaccgttca tagatacagt gtcaatacca acgtgaatca aaacttcagc accatttctt
    25261 gttttcaaac caaaagcgtg ccctgttgga aaggcaattg aaacttcagc atcagctggt
    25321 gcatagacca cgccttggct tggtttcaca gcgatacctt gtcccatagc tccacttgag
    25381 aagactgggt cattgacatc agcaagagcg acaacatcac cgacgatagg agttacaagt
    25441 gtttcatttt gaagagctgc tggcgcaact tcttcttttt cttcagccac ttcagcttgt
    25501 tttgcagctg cagttgcgtc tacttcatct tcgtaaccaa acatgtaagt aagagcaaaa
    25561 ccaagggcaa atgatacagc taccataaga aggtattgtg gaagttgtcc gttaccaaca
    25621 taaagcattg taccagggat gatggtgata ccattaccag taccagcaag tccaaggata
    25681 gaagccaatc caccaccgat tgcaccagca atcaatgaaa ggaagaatgg tttacggaag
    25741 cgcaagttca ccccgaagat agcaggctct gtaataccta gaaaggcaga aagagcagcc
    25801 gggaaagcaa gtgttttcag ttttggattt tttgttttaa caccaactgc aacagtagca
    25861 gcaccttgag ctgtcatagc agctgtgatg atagcgttga atgggttagc atggtcagca
    25921 gcaagtaatt gcacttcaag caagttgaag atgtggtgca cacctgacac gacgatcaat
    25981 tggtgaaccc caccaatcaa gaaaccacca agaccaaatg gcatgctaag aatcgctttt
    26041 gtagcaataa ggatgtagtt ttcaacaacg tggaaaactg gtccaatgac aaagagtcca
    26101 aggatagaca tgaccaaaag tgtcacgaat ggtgttacca agaggtcaat gacatctgga
    26161 acaaccttgc ggacagcttt ttcaaattta gctccgacaa ccccgatgat gaaggctgga
    26221 agaacggaac cttgcaaacc aacaacaggg atgaaaccaa agaagttcat cgctgttact
    26281 tcaccacctt gagcaactgc ccaagcgttt ggaagtgagc cagagacaag catcatacca
    26341 agaacgatac caacggcagg atttccacca aatacacgga aggttgacca cacaaccaaa
    26401 cctggcaaga tgatgaaggc tgtatctgtc aagatttgtg tgtaagttgc aaagtcacct
    26461 ggaagtggca tttcaagagc gttgaaaaga ccacgcacac ccataaagag acctgtcgct
    26521 acgataactg ggatgattgg aacgaaaaca tcaccgaaag tacggatagc acgttggaac
    26581 cagttccctt gtttagcaac ttctgctttc atgtcatcct tagatgatgt tggtaagcca
    26641 agtacaacaa cttcatcgta cattttgtta actgtacctg taccaaagat aatttggtat
    26701 tgccctgagt taaagaaagc accttgaact ttttccaagt tctcaatcac ttctttattg
    26761 attttctctt catctttgac catgacacgt agacgagtcg cacagtgggc aacactattg
    26821 acattttcac gtccgcccaa ggcatcgatg actttttttg caatttcctg attgttcatt
    26881 tgcaaaaatc tccttatata acattttgtt cttgtttgaa agcgatttta ttcgccctta
    26941 cgactattat tttatcatgt tttaaaaata tgtcaagcgt tttgcagaaa aaatattcta
    27001 tccacttagt gagcaagctt tagattgatt gtttttgact gtttcatcag gaattccttg
    27061 aaaaacaagt ttgaaacctt ggttaaaaag tcttttattt cattatcttt cacattttcg
    27121 taaaaattta attgatttcc tgtatttatt ttatgataat cgtttgacag tttttcctct
    27181 tttttaatat aaaaggcttg cattttttat cgaaaacagt tactattaaa agtgataaga
    27241 tttttggagg aatgaatgga atggacaact gagcgtcgtt acagacttta tcaagattgg
    27301 acgcaagaag aaattcaaca tataaaggaa aatatggcac aatctccatg gcatactcat
    27361 taccatgttg agccaaaaac aggacttctc aacgacccaa atggcttttc ttactttgat
    27421 ggcaagtgga tcctctttta ccagaatttt ccttttggtg cagcccacgg tttgaaatct
    27481 tgggcacagc tagaaagtga tgatttggtt cactttaaag aaactggaat caaagtttta
    27541 ccagatactc cattagatag ccacggtgcc tactctggtt ctgccatgaa atttggcgat
    27601 aacttattcc tattttatac aggaaatgtt cgcgatgaaa actggatccg tcacccatac
    27661 cagatcggtg ctttgatgga caaggagggt aagattacaa agattgacaa gatcttgatt
    27721 gaccagccag cagactctac tgaccacttc cgcgatccac aaatttttaa ctttaaaggt
    27781 caatactatg ctgtcgtcgg tggacaggac ttggagaaaa aaggcttcgt ccgtctctac
    27841 aaggctatca ataacgacta cacaaactgg caagcagttg gcgaccttga ctttgctaac
    27901 gaccgtactg cctacatgat ggaatgtcct aatctggtct ttgtagagga acagcctgtc
    27961 cttctctact gtccacaagg attggataag aaagttctag actacgataa tatctttcca
    28021 aatatgtata agattggggc ttcctttgac cctaaaaatg ccaaaatggt agatgtgtct
    28081 caacttcaaa acatggatta cggtttcgaa gcctatgcaa ctcaagcctt caacgctcct
    28141 gatgggcgtg ttctagcagt tagctggctt ggtttgccag atgtttctta cccatctgac
    28201 cgttttgacc accaaggaac cttctctttg gtcaaggaac tcactatcaa agacgacaag
    28261 ctctaccagt atccagtcgc tgctattaag gaccttcgtg cttctgaaga agccttctca
    28321 aaccgttccc aaaccaagaa cacttacgaa cttgaactca acttggaagc taatagccag
    28381 agcgagattg tcttacttgc tgataaagaa ggtaagggac tttcaatcaa ctttgatctt
    28441 gtaaacagtc aagtgacagt ggatcgtagc caggctggag aacagtatgc ccaagaattt
    28501 gggacaactc gttcttgccc tatcgagaat caggctacta ctgctacaat cttcatcgat
    28561 aactctgtct ttgaaatttt catcaataaa ggagaaaaag tattttctgg tcgtgtcttc
    28621 ccacatgcgg accaaaatgg tatcctgatc aaatctggaa acccaactgg aacttactat
    28681 gaattagatt atggtcgcaa aactaactga tgtcgccaaa cttgcaggcg tcagtcctac
    28741 taccgtttct cgggttatca ataaaaaagg gtatctatct gagaaaacca tccaaaaagt
    28801 caatgaagcc atgcgagaat tgggctataa acccaacaac ctggctcgta gtctgcaagg
    28861 aaaatcagct aagttaatcg gcttgatttt ccccaatatt tccaatgttt tctatgcaga
    28921 attgattgat aaattggaac accaactctt caaaaatggt tacaagacca tcatctgcaa
    28981 cagtgaacat gattctgaga aggaacgcga atacatcgaa atgttggaag ccaatcaggt
    29041 ggacggcatc atttctggta gtcacaacct aggaatcgaa gactacaatc gtgtgacagc
    29101 gccgattatt tcctttgacc gaaacctatc gccagacatc cctgtcgtct cctctgacaa
    29161 ctatgctggt ggggttcttg ctgcccaaac cttggtcaag acaggtgccc agtctatcat
    29221 catgattaca gggaatgaca attccaattc gccaaccgga ctgcgccacg ctggttttgc
    29281 atccgtactc ccaaaagctc ctattatcaa tgtttccagt gacttttctc ccgtcagaaa
    29341 agaaatggaa atcaagaata tcttgacccg ggaaaaacca gatgccattt ttgcttcgga
    29401 tgatttgaca gctattctgg tcattaaaat cgctcaagaa ttgggcattt ctgtcccaaa
    29461 agagctcaag gtcatcggct atgatgggac ctactttatc gaaaattact accctcaatt
    29521 ggctactatc aagcaacctt tggaagagat tgcttgtctc actattgatc ttctcttgca
    29581 aaagattgaa ggcaaggaag tcgccacaac tggttacttc ttaccagtta cgctattacc
    29641 aggaaaaagt atttaaacac aagaaaactc agaccgattc gtctgagttt ttatgatctt
    29701 aaattttcga gatagcgctg ggctgtctct aggttaaagg ttttatctga gatgaggcgc
    29761 tctactaggg gagcaacttc agattcacta gccccagcta ggagagctag ggatttggcc
    29821 tgtagtttca tgtggccttg ctggatgccc gtacttacca aggctttgag ggctgcaaaa
    29881 ttttgagcaa gaccgatgga cacgataatc tgggctaatt ctctggcaga aggatttcct
    29941 agtagatcat gactgagagc tacacgtggg ttgaggccga tagagccacc cttagtcgct
    30001 acaggcatgg gcagggtcat ctcaccgacc aattcttctc tttcaaggtc cagcgtccag
    30061 cagctaagac cttgatagcg tccatctcga ctggcaaagg catgggcccc agcttcgatg
    30121 gcacgccagt cattaccagt ggcaatcaaa atcgcatcaa taccattaaa aattccttta
    30181 ttatgagtag cagctcggta aggatcagcc tgcgcaaact gactagccaa tgcaattttc
    30241 tccgcaatct ctcgtccttg atccttttgg cggctcaagt agcgaaaggc catgcgacag
    30301 cttgcagtca ccagagaatc ggtcgcgtag ttggacagga ttcccatgag actctgtccc
    30361 tgactgagtt cttctaagac tggtttcaag gcttccagca tggtgttgag catattggca
    30421 cccatggctt cctgggtatc aacatgaata taaacaacga gaaagtctgg ttcacctttt
    30481 atctgctcga catgcaggtc actcgcccca cccccacgtt taacgataga aggataggct
    30541 tgattggcaa gctccaagag ctccgctttc ttgctggcaa tcttctcttg cgctagttta
    30601 ggattagcaa cttgataaag ggctacctgc ccaatcatct ggcgctgatg gacttgtgca
    30661 gtaaaaccac ctgcacgctt gatgattttg ctggcatagc tggccgccgc aaccacagag
    30721 ggttcttctg tcacataggg aacggtgtat tcctgaccgt tgacaagtac ctccggaacc
    30781 agcgaataag gcagagaaaa agttcccacc acattctcac tcagctggtc tgccacagtc
    30841 acactcatct gttcatcctt ctccagacta gcttgtctct caggactaag gagcgcctga
    30901 gcttttagca gctcgaggcg ctcttggtat gattttttag aaaatccatt ccaacttatc
    30961 ttcattattt ttcaaccttg ctataacggc gttggtggtc aagaatttca accaaggcaa
    31021 aatcttgatt ttcatagcca gcaaactggg cagagtttgt ttcatccaag tttacttcct
    31081 caaaaaagac cttttcatag tctgcaacgg atagggcagt tcgttggttg agcttgttca
    31141 aacggtcttt atccaaataa gcttcatatc cttcaaccaa ttcaccactg aagaactcag
    31201 ccacagctcc acttccgtaa ctataaaggg cgattttatc cccagctttc aagctatctg
    31261 tattttccaa gagagacaaa agtccaagga aaagtgaacc tgtgtagata ttccccacct
    31321 tttgactgta gagaatagac tggtcaaaat gcttttgtaa gaggtctttt ttctcttgag
    31381 gcaggctctt atccatgatt tttttcaagc cttttagcgc taatttagga taaggcaagt
    31441 ggaaacaaac agccgcaaaa tcatccagag taagctggta gcgtttttga tattcaagcc
    31501 aagtcgtttt caaactatcc aagtattgtt gggtagaata aacaccattt acataaggag
    31561 ttgtcgagta atttggtcgc cagaaatcca tgatgtcacg ggtctgagct acattgtcat
    31621 tattaaaggc catcatgcgt ggattttgtg taatcaacat agctacactt ccagcacctt
    31681 gagttggttc tcctggagtt tcaataccgt atttggcaat atcactggca atgaccaaga
    31741 ccttggactc cggagaattt tccacatgca atttggcata atgaagggca gcagtcgctc
    31801 cataacaggc ttctttaatc tcgaaactac gagcaaaggg ctggatgccc agcaagccat
    31861 gcacaaagac ggccgcagcc ttactctggt caattcctga ctcggtagcc acaatgacca
    31921 tgtcaacttc ttgtctttct tgctcagtta aaatagagtc actagcactg gccgccaagg
    31981 tcacaatgtc ctcagttagg ggcgcaatac tcaattcctt gagtaagagt cctttactta
    32041 atttttcagg gtcaattccc ctcgcttctg ctaagtcttg taatttcaag acatattgac
    32101 tggtcgcaaa accaatctta tcaataccga ttgtcatatt tacctctgtt ttatcattca
    32161 tgtaaaaaat cgttctatac tattttatca caaatggcag taaaagagag aaaaaagact
    32221 tgattcacca aatcaagcct cttattggtc atcattttaa agaatgatta gttgctagag
    32281 agttcaccga tataagtagc tttataagct ccattcacag ttatcagctc ctggaggatc
    32341 aaatttcctg agtaagtcct tcccatctca tctacaaatt tttgataaaa ctgactggtc
    32401 ggaatttctc tgacatcctt atcaaatgtc ttatcaagtg ttttactaac cttctcagca
    32461 atcaattgat gctcttgcca tccactttga aactctgagc ccgaactaga aaccatgact
    32521 gggataaaca acaaggtcag tagatttaca gacaataagg aaagtagtag acttcctgca
    32581 aaactagaat cctagttcat gattgataat gccagcaatc aaattcattc gtaatccgaa
    32641 gcgtttacga tgatttcgat aggttgttga aaacatttta aacgttttta ct
//
LOCUS       DAVLDI010000021        31766 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLDI010000021 DAVLDI010000000
VERSION     DAVLDI010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31766
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.021"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(475..567)
                     /locus_tag="VXD01_000993"
     CDS             complement(475..567)
                     /locus_tag="VXD01_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV0601415.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            728..1699
                     /gene="ruvB"
                     /locus_tag="VXD01_000994"
     CDS             728..1699
                     /gene="ruvB"
                     /locus_tag="VXD01_000994"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV0601416.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            1788..2252
                     /locus_tag="VXD01_000995"
     CDS             1788..2252
                     /locus_tag="VXD01_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV0601417.1"
                     /translation="MAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLE
                     KKLREDFPQYQWELKNQVYMHQHSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFE
                     LYAPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            2483..3241
                     /locus_tag="VXD01_000996"
     CDS             2483..3241
                     /locus_tag="VXD01_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV0601418.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            3250..4053
                     /locus_tag="VXD01_000997"
     CDS             3250..4053
                     /locus_tag="VXD01_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV0601419.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLVMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            4075..5334
                     /gene="rseP"
                     /locus_tag="VXD01_000998"
     CDS             4075..5334
                     /gene="rseP"
                     /locus_tag="VXD01_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV0601420.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            5347..7200
                     /locus_tag="VXD01_000999"
     CDS             5347..7200
                     /locus_tag="VXD01_000999"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV0601421.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            7300..8679
                     /gene="bglA"
                     /locus_tag="VXD01_001000"
     CDS             7300..8679
                     /gene="bglA"
                     /locus_tag="VXD01_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV0601422.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGICLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            8871..10679
                     /gene="glmS"
                     /locus_tag="VXD01_001001"
     CDS             8871..10679
                     /gene="glmS"
                     /locus_tag="VXD01_001001"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV0601423.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVVDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLIHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            10798..11847
                     /locus_tag="VXD01_001002"
     CDS             10798..11847
                     /locus_tag="VXD01_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV0601424.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIDGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLDQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(11947..15744)
                     /gene="spuA"
                     /locus_tag="VXD01_001003"
     CDS             complement(11947..15744)
                     /gene="spuA"
                     /locus_tag="VXD01_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV0601425.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVEIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSIPSK
                     PEHQNEASHPAYQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            16161..16574
                     /gene="rpsL"
                     /locus_tag="VXD01_001004"
     CDS             16161..16574
                     /gene="rpsL"
                     /locus_tag="VXD01_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV0601426.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            16594..17064
                     /gene="rpsG"
                     /locus_tag="VXD01_001005"
     CDS             16594..17064
                     /gene="rpsG"
                     /locus_tag="VXD01_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV0601427.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            17489..19570
                     /gene="fusA"
                     /locus_tag="VXD01_001006"
     CDS             17489..19570
                     /gene="fusA"
                     /locus_tag="VXD01_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV0601428.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            19674..24065
                     /locus_tag="VXD01_001007"
     CDS             19674..24065
                     /locus_tag="VXD01_001007"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV0601429.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKFLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            24167..24430
                     /locus_tag="VXD01_001008"
     CDS             24167..24430
                     /locus_tag="VXD01_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV0601430.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            24423..24701
                     /locus_tag="VXD01_001009"
     CDS             24423..24701
                     /locus_tag="VXD01_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV0601431.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            24722..24874
                     /locus_tag="VXD01_001010"
     CDS             24722..24874
                     /locus_tag="VXD01_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601432.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            24896..26137
                     /locus_tag="VXD01_001011"
     CDS             24896..26137
                     /locus_tag="VXD01_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV0601433.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     IFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            26147..26377
                     /locus_tag="VXD01_001012"
     CDS             26147..26377
                     /locus_tag="VXD01_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0601434.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            26600..27322
                     /locus_tag="VXD01_001013"
     CDS             26600..27322
                     /locus_tag="VXD01_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0601435.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            27539..28873
                     /gene="pepC"
                     /locus_tag="VXD01_001014"
     CDS             27539..28873
                     /gene="pepC"
                     /locus_tag="VXD01_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV0601436.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(28929..29840)
                     /locus_tag="VXD01_001015"
     CDS             complement(28929..29840)
                     /locus_tag="VXD01_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV0601437.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(29864..30667)
                     /locus_tag="VXD01_001016"
     CDS             complement(29864..30667)
                     /locus_tag="VXD01_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV0601438.1"
                     /translation="MSIISMVLVIVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(30695..31684)
                     /gene="manX"
                     /locus_tag="VXD01_001017"
     CDS             complement(30695..31684)
                     /gene="manX"
                     /locus_tag="VXD01_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV0601439.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
BASE COUNT         9038 a         6124 c         7428 g         9176 t
ORIGIN      
        1 gctctatttc aggcttttgg ggactattct aaaaataatt tttcgatatt tttcggtatt
       61 tttcggattt tggtcgggga attggcgggg acttttttag cgaatataac taagaaatag
      121 gtctgtggtc gcttcagcta gttcaaactc aatttgattg taagtgactg ttaattgaag
      181 aactggaact actgtaataa tgattttgct tgtctagtag tggcgtatta aatgagaagt
      241 gacatgtaag attgtctctt cgtttacgaa atcaaaattt ctatgaaatt gatagaatcc
      301 ctaacgttct cttaatctta accgtcttgt cgtacagcgg ttgaagaaaa tgtaaacctt
      361 tgacaaaatt cgtgaactat gggataataa aaaggaattg agtactagtt ctatatcata
      421 ggctagaaaa gaccccaagc tcacgaccaa ataagcttgg ggtctttttt gacactattt
      481 gtccttgttt agccatttat cgactatacg aagaacgaca ccgaccacaa ttggtccgat
      541 gatagttttg agtactaatt ccatcatggg ctatctcacc tcctttcgta ggcggtgtag
      601 cagtgtcgta gaatattata ccacataagt gctaaactta ggagtcaccc aatcaggtgg
      661 cttttttgtt tgtggcttgg ttttttgata taatagagcc atgagtagaa ttttagataa
      721 tgagataatg ggggatgagg agttagtaga acgcacgctc cgtcctcagt atttacgtga
      781 atatattggg caggataagg ttaaggacca gcttcaaatc tttatagaag ctgccaaaat
      841 gcgagatgaa gcgctggatc atgtcctctt atttgggcct ccaggtttgg ggaaaacaac
      901 catggctttt gtcattgcca atgaactggg agtcaatctc aagcaaacgt ctggtcctgt
      961 tatcgaaaaa gcgggtgatt tggtagcgat tttgaatgag ttagagcctg gagatgtcct
     1021 ctttattgac gagattcatc gcttacccat gtcagtggaa gaagtgcttt atagtgccat
     1081 ggaggacttc tacatcgata ttatgattgg ggctggtgaa ggcagtcgca gtgttcattt
     1141 ggagttgcct ccttttacct tgattggtgc gacgactcgg gctggtatgc tctcaaatcc
     1201 actacgggca cgttttggga ttacaggtca tatggagtat tatgcccatg ctgacttgac
     1261 agaaattgtc gagcggacgg cagatatttt tgagatggaa atcactcatg aggcagcatc
     1321 tgagttggcc ctacgtagtc gtggaacccc tcgtattgcc aatcgtctcc tcaagcgcgt
     1381 gcgcgatttt gcccagataa tggggaatgg ggtaatcgat gatattatta ccgataaggc
     1441 tttgactatg ctggatgttg accatgaagg tttggactat gtggatcaaa aaatccttcg
     1501 taccatgatt gagatgtaca gtggaggacc tgttggtcta ggaactcttt ctgtcaatat
     1561 cgccgaagag cgtgagacag ttgaagacat gtatgagcct tacttgattc aaaaaggttt
     1621 tatcatgcgg acacggtctg gacgggtggc gactgctaag gcatatgagc acttaggtta
     1681 tgaatacagt gaaaaataag caagaaatct tagaggcttt tagagaaaat ccagatatga
     1741 tggccattct gacgatcatc cgagaccttg gtttgaaaga ctcgtagttg gcagcaggtt
     1801 ctgtcagaaa tttcatctgg aatcttttgt cagacaaatc cccttttgat catgaaacag
     1861 atatagatgt gattttcttt gatccagatt tttcttatga ggaaacctta ttactggaga
     1921 aaaagctgag agaggatttt cctcagtacc agtgggaatt gaaaaatcag gtctatatgc
     1981 atcagcacag tcctcacact gcttcctata ccagttctcg tgatgctatg agtaagtatc
     2041 cagaacggtg tacggcagtt ggactgcgct tgaatgaaga atcagatttt gaactctatg
     2101 caccttatgg tttggaggat attttgaatt ttcaagttcg tccaactcct catttcttag
     2161 aaaatgaaga ccgaatggaa ctctatcaaa cacgtttatc caagaaaaat tggcaggaga
     2221 aatggaaaaa tttgattttt aaaaatactt aaggaaactt taagctaggg agtgtacact
     2281 aagttcataa gttaagaaga ccttaactta aactcctaaa actttttcat aataatctcc
     2341 ctataaaaat aaagtcgccc aatcaggcgg cttatttttt tgaaaaatgg gcatggtgcc
     2401 tgagaataaa tagcttagtg atagaagaaa atggggaaat atggtataat gaaacgatag
     2461 atttttgaat aggaataaga tcatgtttgg attttttaag aaagataagg ctgtggaagt
     2521 agaggttccg acacaggttc ctgctcatat cggcatcatc atggatggca atggccgttg
     2581 ggctaaaaaa cgtatgcaac cgcgagtttt tggacataag gcgggcatgg aagcattgca
     2641 aaccgtgacc aaggcagcca acaaactggg cgtcaaggtt attacggtct atgctttttc
     2701 tacggaaaac tggacccgtc cagatcagga agtcaagttt atcatgaact tgccagtaga
     2761 gttttatgat aattatgtcc cggaactaca tgcgaataat gttaagattc aaatgattgg
     2821 ggagacagac cgcctgccta agcaaacctt tgaagcttta accaaggctg aggaattgac
     2881 taagaacaac acaggattga ttcttaattt tgctcttaac tatggtggac gtgctgagat
     2941 tacacaggcg cttaagttga tttcccagga tgttttagat gccaaaatca acccaggtga
     3001 catcacagag gaattgattg gtaactatct ctttactcag catttgccta aggacttacg
     3061 agacccagac ttgattatcc gtactagtgg agaattacgt ttgagcaatt tccttccatg
     3121 gcagggagcc tatagtgagc tttattttac ggacacctta tggcctgatt ttgacgaagc
     3181 ggccttgcag gaagctattc ttgcctataa tcgtcgtcat cgccgatttg gaggagttta
     3241 ggaggaaata tgacccagga tttacagaaa agaaccttgt ttgcagggat tgccctggct
     3301 attttcctac caattttaat gattgggggc ctcttgcttc agatagcaat cggaatcata
     3361 gccatgctag tcatgcatga acttttgaag atgagaggtc tagagaccat gacgatggag
     3421 ggcctcttga ccctctttgc aacctttgca ttgaccattc ccttggagaa ttacctgact
     3481 tttttgccag ttgatgggaa tgtggttgcc tatagtgttt tgatttcaat catgttagga
     3541 acgaccgttt ttagcaagtc ttatacgatt gaggatgcgg ttttccctct tgctatgagc
     3601 ttctacgtgg gctttggatt taatgcttta ctagatgctc gtgttgcagg tttggacaag
     3661 gctctcttag ccttgtgtat cgtctgggcg acagacagtg gtgcctatct tgttgggatg
     3721 aactatggga aacgaaagtt agcaccaagg gtatcgccta ataaaaccct tgagggtgcc
     3781 ttgggtggta ttttaggagc aattttagta accattatct ttatgatagt tgacagtaca
     3841 gttgctcttc catatggaat ttacaagatg tcagtctttg ctattttctt tagcattgct
     3901 ggacaatttg gtgatttact agaaagttcg atcaaacgtc attttggtgt taaggattct
     3961 gggaaattta tccctggaca tggtggtgtt ttggatcgtt tcgatagtat gttgcttgta
     4021 tttccaatca tgcacttatt tggactcttt taatcaaaag acggaggaaa cgctatgctc
     4081 ggaattttaa cctttattct ggttttcggg attattgtag tggtgcacga gttcgggcac
     4141 ttctactttg ccaagaaatc agggatttta gtacgtgaat ttgccatcgg tatgggacct
     4201 aaaatttttg ctcacattgg taaggatgga acggcctata ccattcgaat tttgcctctg
     4261 ggtggctatg tccgcatggc cggttggggt gatgatacaa ctgaaatcaa gacaggaacg
     4321 cctgttagtt tgacacttgc tgatgatggt aaggttaaac gcatcaatct ctcaggtaaa
     4381 aaattggatc aaacagccct ccctatgcag gtgacccagt ttgattttga agacaagctc
     4441 tttatcaaag gattggttct ggaagaagaa aaaacatttg cagtggatca cgatgcaacg
     4501 gttgtggaag cagatggtac tgaggttcgg attgcacctt tagatgttca atatcaaaat
     4561 gcgactatct ggggcaaact gattaccaat tttgcaggtc ctatgaacaa ttttatctta
     4621 ggtgtcgttg ttttttgggt tttaatcttt atgcagggtg gtgtcagaga tgttgatacc
     4681 aatcagttcc atatcatgcc ccaaggtgcc ttggccaagg taggagtacc agaaacggca
     4741 caaattacca agattggctc acatgaggtt agcaactggg aaagcttgat ccaagctgtg
     4801 gaaacagaaa ccaaagataa gacggcaccg actttggatg tgactatttc tgaaaagggg
     4861 agtgacaaac aagtcactgt tacacccgaa gatagtcaag gtcgttacct tctaggtgtt
     4921 caaccggggg ttaagtcaga ttttctatcc atgtttgtag gtggttttac aactgctgct
     4981 gactcagctc tccgaattct ctcagctctg aaaaatctga ttttccaacc ggatttgaac
     5041 aagttgggtg gacctgttgc tatctttaag gcaagtagtg atgctgctaa aaatggaatt
     5101 gaaaatatct tgtacttctt ggcaatgatt tccatcaata ttgggatttt taatcttatt
     5161 ccgattccag ccttggatgg tggtaagatt gtgctcaata tcctagaagc catccgccgc
     5221 aaaccattga aacaagaaat tgaaacctat gtcaccttgg ccggagtggt catcatggtt
     5281 gtcttgatga ttgctgtgac ttggaatgac attatgcgac tcttttttag ataatcgagg
     5341 aatattatga aacaaagtaa aatgcctatc ccaacgcttc gcgaaatgcc aagcgatgct
     5401 caagttatca gccatgctct tatgttgcgt gctggttatg ttcgccaagt ttcagcaggt
     5461 gtttattctt atctaccact tgccaaccgt gtgattgaaa aagctaaaaa catcatgcgc
     5521 caagaattcg aaaagattgg tgctgttgag atgttggctc cagcccttct tagtgcagaa
     5581 ttgtggcgtg aatcaggtcg ttacgaaacc tatggtgaag acctttacaa actgaaaaac
     5641 cgtgaaaaat cagactttat cttaggtcca actcacgaag aaacctttac agctattgtc
     5701 cgtgattctg ttaaatctta caagcaattg ccactcaacc tttatcaaat tcagcccaag
     5761 tatcgtgatg aaaaacgccc acgtaatgga cttcttcgta cacgtgagtt tatcatgaag
     5821 gatgcttata gtttccacgc taactatgat agtttggata gtgtttatga tgagtacaaa
     5881 gcagcctatg agcgtatttt cactcgtagt ggtttagact tcaaggctat tattggtgac
     5941 ggtggagcca tgggtggtaa ggatagccaa gaatttatgg ccattacatc tgctcgtaca
     6001 gaccttgacc gctgggttgt cttggacaag tcagttgcct catttgacga aattcctgca
     6061 gaagtgcaag aagaaatcaa ggcagaattg ctcaaatgga tagtctctgg tgaagatacc
     6121 attgcttact caagtgagtc tagctatgca gctaacttag aaatggcaac aaacgagtac
     6181 aaaccaagca accgtgttgt cgctgaagaa gaagttactc gtgttgcaac gccagatgtt
     6241 aaatcaattg atgaagttgc agctttcctc aatgttccag aagaacaaac gattaaaacc
     6301 ctcttctaca ttgcagatgg tgagcttgtt gcagcccttc tagttggaaa tgaccaactc
     6361 aacgaagtca agttgaaaaa ccacttggga gcagatttct ttgacgttgc tagcgaagaa
     6421 gaagtggcga atgttgttca agcaggattt ggttcacttg gaccagttgg tttgccagag
     6481 aatattaaaa ttattgcaga tcgtaaggtg caagatgttc gcaatgcagt tgtcggtgct
     6541 aacgaagatg gctaccactt gactggtgtg aacccaggcc gtgattttac tgcagaatat
     6601 gtggatatcc gtgaagttcg tgagggtgaa atttccccag atggacaagg tgtccttaac
     6661 tttgcgcgtg gtattgagat cggtcatatt ttcaaactcg gaactcgcta ctcagcaagc
     6721 atgggagcag atgtcttgga tgaaaatggt cgtgctgtgc caatcatcat gggatgttac
     6781 ggtatcggtg tcagccgtct tctttcagca gtgatggagc aacacgctcg cctctttgtt
     6841 aacaaaacgc caaaaggtga ataccgttac gcttggggaa tcaatttccc taaagaattg
     6901 gcaccatttg atgtgcattt gattactgtc aatgtcaagg atgaagaagc gcaagccttg
     6961 acagaaaaac ttgaagcaag cttgatggga gctggttatg aagtcttgac agatgaccgt
     7021 aacgaacgtg tcggtgttaa atttagcgat agtgacttga ttggtcttcc aatccgtatc
     7081 actgttggta aaaaagcggc cgatggcatt gtagaagtta agatcaaggc aactggtgac
     7141 accattgagg ttcatgcaga taacgtgctt gaaacgcttg aaatcctaag caagaaataa
     7201 aaactataat cagaagaaaa acaaggaaaa aatgtaacta gtttttacct tgttttttct
     7261 gtataatggg agaaatgagt agataaagag gtaaatgtta tgctaagatt tccaaaggat
     7321 tttgtctggg gatcctctac ttctggaccg cagacagaag gacgtgtagc tggtgacggt
     7381 aagggagaca atctctggga ttactggttc caagtggagc caaatcgtta ctataatggg
     7441 attggttcag ataagacatc gactttttat gaaaattggg agcgggatat tgagcttttg
     7501 ttagagactg gtcacacagt ctttcggact tctattcagt ggtcacggat ttttccacaa
     7561 ggctgtggaa aagtcaaccc tcaaggtgtg gatttttatc gtaaggtctt tgaggctatt
     7621 aaggctaaag gaatttgtct gttagtcaat ctctatcatt ttgatttacc ttttgccctt
     7681 caagaggatg gtgatggttg ggaaaataag gcgacagtct cagcctatga agactatgct
     7741 cgtttttgtt ttgagactta tggagattta gtggatcaat ggattacctt taacgagccc
     7801 atcgttcctg tagaatttgg ttatttttat gatgcccatt atccacataa ggtggatgca
     7861 gaggcagctg ttaaggtagc ctatcataca caattggcca gcagccgggc tgttaaggct
     7921 tgccatgaac ttttgcctga ttccaagatt gggattgtcc tcaacttgac accggcttat
     7981 ccacgtagcc agcatcctgc tgatgtcaag gcagctcgta ttgcggccct ttttcaggcc
     8041 caatctttct tagatccatc tgtcttgggg acttatccac aggagttggt agaaatcttg
     8101 catgaacacg gtcttttacc tgatgctaca gaggaagagt tggaactcat tcgtgataat
     8161 acggtggact tccttggtgt gaactactat caacctttgc gtgttatggc tcctcgattt
     8221 gctaagcatc cagagagtcc actcttacca gaacattttt acgagcctta tgtgatgcct
     8281 ggacgtaaaa tcaattctca tcgtggttgg gagatttatg agcaagggat ttatgacatc
     8341 gcccaaaata tcaaggaaaa ttatggcaat attgagtgga tgttgactga gaatggtatg
     8401 ggtgttgaag gggaagaaaa attccgtcaa gatggaatga ttcaagatga ttaccgtatt
     8461 gactttgtaa aaggtcatct tcgtgaactt caccgtgcca ttgaagatgg tgccaactgt
     8521 aagggctact tgatttggac ctttattgac tgctggtcat ggctcaacag ctataaaaat
     8581 cgctatggtt tggtcgaatt agacttggaa acgcaagaac gtcgtctgaa gaaatcaggc
     8641 cactggttca agaaactaag cgacaataat ggattttaaa aaggactctg actgattatc
     8701 ccaatcggtc agagtttttt gcttacagga gcttaatttg aactatacca atttttactc
     8761 ttgacaagtg aaagaaacaa gtatatactg tttttgctga ttctataaaa gatgaattag
     8821 actataccaa ttttaaggag aaagcacagc ttgcctgtgt cgtatatact atgtgtggaa
     8881 ttgttggtgt tgttggaaac acaaatgcaa ctgatatttt gattcaaggg cttgaaaagc
     8941 ttgaataccg tggctatgat tctgcgggaa tttttgtcct agatggtgct gataaccatt
     9001 tggtgaaggc ggttggtcgt attgcagaat tgtctgccaa gacagctggt gttgagggaa
     9061 caactggtat cggacatact cgttgggcta ctcacggaaa accaactgag gacaatgctc
     9121 acccacaccg ctctgagaca gaacgttttg tcttggtgca taatggggtg attgagaact
     9181 atcttgaaat caaggaagaa taccttgcag gtcaccactt caaggggcag acagatactg
     9241 aaatagccgt tcatttgatt ggaaaatttg cggaagaaga agggctctca gttcttgaag
     9301 ccttcaaaaa agcccttcac atcatccgtg gttcttatgc ctttgccttg gttgactcac
     9361 aagatcctga agtcatctac gtagctaaaa ataaatcacc acttttgatt ggtcttggag
     9421 aaggctataa catggtctgc tcagacgcca tggctatgat tcgtgaaact aaccaataca
     9481 tggaaatcca tgaccaagag ttggtaatcg tcaaggctga tagtgtggaa gttcaagact
     9541 atgatggaaa tcgtcgtgag cgtgctagct acactgctga acttgacttg tcagatatcg
     9601 gtaagggaac ttacccttac tacatgctca aggaaattga cgagcaacca actgttatgc
     9661 gtaaactcat tcaagcctac acggatgatg ctggtcaagt agtggttgat cctgctatca
     9721 ttaaggctgt tcaagacgca gaccgcatct acatccttgc agctggaaca tcttaccatg
     9781 caggatttgc ttctaagaaa atgttggaag aattgacaga tacaccagtt gaacttggca
     9841 tctcatctga gtggggctac ggtatgccac ttctcagcaa gaaaccactc ttcatcttta
     9901 tcagccaatc tggtgaaaca gcggatagtc gtcaagtttt ggtcaaggct aatgaaatgg
     9961 gaattccaag cttaacagtg acaaatgttc caggctcaac cctctcacgt gaagccaact
    10021 ataccatgct ccttcacgca ggtcctgaaa ttgccgtggc atcaactaaa gcctatacag
    10081 cgcaaatcgc agcccttgcc ttccttgcaa aagcagtcgg agaagcaaat ggtaatgcta
    10141 aagcgcaagc ctttgacctg attcatgaat tgtcaatcgt agctcagtct atcgaatcaa
    10201 ctctttcaga gaaagaaacc attgaagcca aggttcgtga acttcttgaa acaactcgta
    10261 acgcctttta catcggacgt ggtcaagatt actacgtagc catggaagca agtctcaaac
    10321 tcaaagagat ttcttatatc cagtgtgaag gctttgctgc aggagaactc aagcacggaa
    10381 ccattgcctt gattgaagaa ggaacgcctg ttttggctct cttgtcagat ccagttcttg
    10441 ccaatcatac tcgtggaaat atccaagagg tcgcagcccg tggtgccaaa gtcctcacta
    10501 tcgcagaaga gaatgtagcc aaagataccg acgatatcgt ccttacgacc gtacatccat
    10561 acctctcacc aatttcaatg gtcgtaccaa cgcaattagt cgcttacttt gcaaccctcc
    10621 accgtggcct cgatgtggat aaaccacgta accttgctaa atcagtaacg gtagaataag
    10681 ctaaaaaagt ctagttatct aggctttttc taatgagcaa attggttgct tgtacttaag
    10741 attcgtgtta gaataatttt tcaaattgaa ggacagagat agacaaggag aatcacaatg
    10801 gtagaattgg gaatttcaac atttggggaa ataacggagc ttgaagggac tggacaaact
    10861 tacagtcatg ctgaacgcat tcgccagttg gtggcagaga ttgagctggc tgacaaggtt
    10921 ggtttggacg tatatgggat tggcgagcac catcgggcgg attttgcagt atcagcccca
    10981 gagattgtcc tggccgctgg ggcagtcaat accaagaaaa tccgtttgac cagcgcagtc
    11041 agcattctgt caagcatgga cccgattcgt ttgttccaac agtatgccac tatcgatgct
    11101 ttgtcaaatg gacgagcgga gattatggct ggaaggggct ctttcacgga atctttccct
    11161 ctgtttggtt atgacttgaa agactacgac tctctttttg atgagaaatt agacttgctt
    11221 cagttagtca atgaaaagac caagttagac tggcaaggtc gattgactca aacgattgct
    11281 ggtaaagaag tttatcctcg tccagttcag gacaaattgc ccttgtggat agctacaggt
    11341 ggtcatgtcg aatcaacagt gaagattgct caggctggtc taccgattgt atatgctatt
    11401 attgatggta atccacgtta ttttaaaaag ttgattcagg cttatcgtga gattggaagc
    11461 gaagcgggcc atgctgacaa agacttgaaa gtgggagccc attcttgggg gtggattgcg
    11521 gaagatggtg agcaggcggt gaaagattat ttccatccga ctaagcaagt ggtggatgct
    11581 atttccaaag accgtccgca ctggcaggaa ttgcgttatg agcaatattt ggatcaggta
    11641 gggtcaaatg gcgccatgtt tgttggcaat ccagatcagg tggccgaaaa attgattcgc
    11701 atgatagagg atttaggatt ggaccgcttc atgcttcatc taccgcttgg ttctatgcct
    11761 catgaccagg ttctgagagc tattgaactc ttcggaacac aagttgcacc caaagtacga
    11821 gcttattttg ctatgaaaga ggcttaataa aaaatcctaa tcaagtttat taggacaaca
    11881 aatattgtac gaaaattaat cccccgagct ataatgcttg ggggattttt ctataggagg
    11941 gctagtttag ttctcttttt tattttttag taagaaaccg agaccaagga gcgcaaggag
    12001 gctgattcct gcaaatagga gtttgttttc gtttttgatt cctgtatttg gaagttcagc
    12061 ttgtctatct ggggttgcag gtatattttt cttgctagag ttttctaccg attcgttttg
    12121 aaccgcttct tttacagatg atgcttgtgc ttcttgtgct ggttgttcag cttgtgaatc
    12181 agctgtagct tggctaggtt tattttccgc atcagctact ttggcatctg gtttagtaga
    12241 atcaggtcta gcttctggag ctgggtcttg atatgcaggg tgagaagctt cattttgatg
    12301 ttcaggcttg gaagggattg agtctggttt ctcttctgca gttgactcat ggctagttcc
    12361 attttgagag actcgaagaa cagtagctgt aagggcattc aatttcaagc ctttttcagt
    12421 ccattcaagt cctttcgggt tggcaatttc gactgatcct gcttggtttt catctgccaa
    12481 aacttccgca tttcttagat gtgcaaaggc agttcccaaa ttaaattcgc gagctttttc
    12541 atccgcattg acaaagactg cgtagatatc gccgtttgga gcagtgattt ggtagccaat
    12601 cactacatcc tctttttcca caccattttg gcctgggaca gtgatgaggt ggacacggtc
    12661 tttgatatct tgaagactct taagtcggaa ggcatctgta gattgacgaa gggcaatcaa
    12721 acctttcata tagtcacggc tcttgacatt ttcaggataa gctttaccat ctgtagcctt
    12781 agtccagtca aacttgttga ctgcatcgct agaatcgtaa gaatcatgga tgaagtaagg
    12841 atagtcaaat gggttgccgt ccttatcacg caacaagtga gatttgtttg gaaccttatc
    12901 ctctgctact ggagtcttgt aggctgggtc acggaattgt ttagtacgtc catattcctg
    12961 accggagtgg ataaatggag ttccttgagc tgtcaagacc atgagatttc caagtcgtaa
    13021 acgacggtgg atttcagcat agttctcagc cttgcttggg tcttttttga tagactgggc
    13081 aatgatgtca aagagggtca agttatcatg ggctgctatg tattggatga catctccagg
    13141 gctgtcagct tcaaagttag ttggttgagc aatgagattt ttaaagatgg tgttgacatc
    13201 acgcttgcca cctgtgataa aggcaggttg accttcgttt ggataaccag atttgaggtt
    13261 gttacggatg tcatctgaaa agacagcgac agtatcggta tgtttcatcc aatcttggtc
    13321 agcagcttta gtaggcatgt tttcatcacc ggcataggtt ctccaacctt caccaagcat
    13381 gatgaggttt ggattgaggg cgcgtgcagc cttgtaagct tcttcgatag aagcggcgtc
    13441 atggtctccc atcatatcga agcggaagcc atccactttg taggtatcaa ctaggtattt
    13501 gatagagtca actaggagcc gtttggtcat atggtgggtt gtccccaagc gtccaccacc
    13561 aaagctagtt cgaggtgtgc catctgcatc cataaagtgg tagtagtttg gctctaggtc
    13621 ttcaaagata tcgactttgg ctgtgtggtt ataaacgaca tctaggatag ctcccatacc
    13681 acgtttgtgg atttcgttga tgaggttttt aaattctgcg attcgttttt ctggattctt
    13741 aggatcgctt gagtacatac cagtcaagga gaagtagttt tgagggtcat atccccagtt
    13801 gtagttgctg ttgcttgaag cgtagtcaga caagcgttca tggtttttca attcattgac
    13861 aaagtagtaa gacaagactg gaaggagctg gatatgggtt acacccaagt ctttgagata
    13921 gtctagtttt tcaatgaagg cttcaaaagt cccaaatggt ttggtcaagt cttttgcaat
    13981 ggcaggatct gaagtgaagt cacgcacatg agcttcgtag ataacggcgt cttcacgagt
    14041 cttgaaattg tgaatcttac cataagtcaa gtcttgaggt ccgagtttag ctggatctac
    14101 aaaggcggct ttagccactt tatgggcatc gtcaatcttg gcatcgtcgc tattccaagc
    14161 agcaagagat ttagcgtaag gatcgagtgc aagaacagtt ttaccttgac gctcgatttg
    14221 gtattgataa tagtatccag tgaaatctgt gattccgagt ttgtttgtgc tgtctagagt
    14281 ttgtttccaa gttcctcttt cccctttttc aagagcgaca gttccaacta ctttgtcagg
    14341 gtcattcttg tcgtagacaa caacagaaac cttatcagca cttggtgacc aaagggtcaa
    14401 atcaacttgt tttccttctt cttttaggtc agctcccagt ttgccatcat agctgtatgt
    14461 ctcatctttc aggcgccagc ttgttttggt agtgaattgg tcggaattgt agctaacagt
    14521 ataaggatgt tttgtgtcag agaaatctcc gctgtaggtc actttcttac cagcttcatc
    14581 gattgcaaca tcggtaatag ttaccttgtt tcctaggtga ttagtgatgt tggagtgttt
    14641 gaggatatct tcttttttag caccgacaag tgttgaaaag ctactttcaa tgctagaagt
    14701 gcctacgtgt tgggctcctg tcatacggat atcatggaca tagtatggat ttgtgtaaat
    14761 cgattcatca tcgtctttta ggaaaatttg gctatgattt ttcaaatctg tgaacttata
    14821 attttcttta cggattttca cgtcgtctcc ttgtttgctc tcatctagta ataaaaatcc
    14881 aaattctctt gcggcttcat taagaggaat gtcgatatag cggccatatt tgcctgtagc
    14941 cgtaaagtct gttccgtcag gccattgagc gctacttgga ttttttacat ctccccagta
    15001 ccagagagat ttcttgtcat agttgccatc tgtgcggtag tagttgacgc gaacagttcc
    15061 tgcaggctgt ggctcgtaag agaaaacctt gtaatcttgg tctaaccaag cctcgttcat
    15121 ttttggaact agtttttcta cagatttatc gccggttaga ttttttccag ctgtattgtt
    15181 gatgaggaag ctaattttct tggcttgttc tccctttaat ttgacatcta ggtaatagcc
    15241 gtagtcatct ttcttggcat ccttgaagga caaagctccg tttggccagt tttcagatgg
    15301 tttttcaaca tcgtcccaag tccatagtcc ttgagcatcc ttgttttctt caggaagttt
    15361 tttgacatgg atacggaagt agttatcttc gatgggctct tctgccttag tttcagttgt
    15421 tactggacta gtagaagtag ttggctctgt tgcaggtttt tcttctgttt tctctaggga
    15481 agcgtttgca tttctaggtg aagaaatatc actttcgttc ttaccagagc cagctgctgt
    15541 atcagtaaga ggttgggcaa gggtggttgt atttctgttg ttgggttcgt tagtggttgg
    15601 tgtactttcg tcggatgaga tagttggtgt agccatggca agcaagacaa ggcttgcgcc
    15661 gataaggaca gaaccagttc catttttgag ggaacggatg ctgtagacca tttttttctc
    15721 agtgtgagat ggtgtttttc tcataatgat tctccaatca ataaatttct atatcagtat
    15781 agcatgtagt aaaataatat gcaagcgttt tctttgattt gtgaaaaaaa ttcttacttt
    15841 tgagaagttt tctgtactat tttatatatc agtataaatg acggagataa aaatgtcaca
    15901 taagccaagc cgtattatta ggaagatgat gtgttcccag ctatttttat tcagaaattg
    15961 atctctaaca ttaccaataa aaatgaaaaa tatcttgaca agcaagggaa aattttgtta
    16021 caatgataga cggtactttt tacttttggt ctctcaagag tgtacaggga cgtgctgaca
    16081 aatgttgcaa aagtacacac agatgatatc tgtcaccaag tgtatcatca ccaaaaataa
    16141 aaaaacacag gagaatgtag atgcctacaa ttaaccaatt ggttcgcaaa ccgcgtaaat
    16201 caaaagtaga aaaatctaaa tcaccagctt tgaacgttgg ttacaatagt cataaaaaag
    16261 ttcaaacaaa cgtttcttca ccacaaaaac gtggtgttgc aactcgtgtt ggaacaatga
    16321 cacctaaaaa acctaactca gcccttcgta aattcgctcg tgtacgtttg agcaacctta
    16381 tcgaagttac tgcctacatc ccaggtatcg gacacaactt gcaagagcac agcgtggtgc
    16441 ttcttcgcgg tggacgtgta aaagaccttc caggggtacg ttaccatatc gtccgtggtg
    16501 cacttgatac tgcaggtgtt aacgatcgta aacaaggccg ttctaaatac ggtactaaac
    16561 gtccaaaagc ataaggaaag gggataaaga gaaatgagtc gtaaaaatag agctccaaaa
    16621 cgtgacgtat tgccagatcc gctatacaat tcacaactag ttactcgtct tatcaaccgc
    16681 gttatgcttg atggtaaacg tggtactgct gcttcaatcg tttacggtgc ttttgagcaa
    16741 atcaaagaag ctactggcaa cgatgcactt gaagtatttg aaacagctat ggaaaacatc
    16801 atgcctgtac ttgaagtacg tgcacgtcgt gttggtggtt ctaactacca agtcccagtt
    16861 gaagttcgtc cagaacgtcg tacaacactt ggacttcgtt ggttggtaac aatcgctcgt
    16921 cttcgtggtg aacacacaat gcaagaccgt cttgcaaaag aaatcttgga tgctgctaac
    16981 aacactggtg cagctgttaa gaaacgtgaa gatactcacc gtatggctga agctaaccgt
    17041 gcattcgcac acttccgttg gtaagatagg atgcgaaagc gttaagaaag tcccagagaa
    17101 aatagggaat cgaagcaggt tgcggttgca accaatgaga ttcatctttt tctccagact
    17161 tttagcttga gctcaactaa atcatgatgc taggcacggt aaggatgcaa ggtgaaaata
    17221 ggaaactgac gcagtattca acgaatacaa ggagttttat ctttttcacg cagcatcccg
    17281 ttccagctca catcggctaa ctaactttag cccgggttca aattagctaa atcgattagt
    17341 attagctata actcagctta ccatctagta agttgaaacc aacaatagca tgaaaacatt
    17401 gagaacgggt aggtcctgcc tatccgtttt tattaaaatc gtgttataat agaatagaaa
    17461 tcaaaaataa ataggagaaa caaacctcat ggcacgcgaa ttttcacttg aaaaaactcg
    17521 taatatcggt atcatggctc acgtcgatgc cggtaaaaca acaactactg agcgtattct
    17581 ttactacact ggtaaaatcc acaaaatcgg tgaaactcac gaaggtgcgt cacaaatgga
    17641 ctggatggag caagagcaag aacgtggtat cacgatcaca tctgctgcga caacagctca
    17701 atggaacaac caccgcgtaa acatcatcga cacaccagga cacgtggact tcacaatcga
    17761 agtacaacgt tctcttcgtg tattggatgg tgcggttacc gttcttgact cacaatcagg
    17821 tgttgaacct caaactgaaa cagtttggcg tcaagcaact gagtacggag ttccacgtat
    17881 cgtatttgcc aacaaaatgg acaaaatcgg tgctgacttc ctttactctg taagcacact
    17941 tcacgatcgt cttcaagcaa atgcacaccc aatccaattg ccaatcggtt ctgaagatga
    18001 cttccgtggt atcattgact tgatcaagat gaaagctgaa atctatacta acgaccttgg
    18061 tacggatatc cttgaagaag acatcccagc tgaatacctt gaccaagctc aagaataccg
    18121 tgaaaaattg attgaagcag ttgctgaaac tgacgaagaa ttgatgatga aatacctcga
    18181 aggtgaagaa atcactaacg aagaattgaa agctggtatc cgtaaagcga ctatcaacgt
    18241 tgaattcttt ccagtattgt gtggttcagc cttcaaaaac aaaggtgttc aattgatgct
    18301 tgatgcggtt atcgactacc ttccaagccc acttgacatc ccagcaatca aaggtattaa
    18361 cccagataca gacgctgaag aaactcgtcc agcatctgac gaagagccat ttgcagctct
    18421 tgccttcaag atcatgactg acccattcgt aggtcgtttg acattcttcc gtgtttactc
    18481 aggtgttctt caatcaggtt catacgtatt gaatacttct aaaggtaaac gtgaacgtat
    18541 cggacgtatc cttcaaatgc acgctaacag ccgtcaagaa atcgacactg tttactcagg
    18601 tgatatcgct gctgccgttg gtttgaaaga tactacaact ggtgactcat tgacagatga
    18661 aaaatctaaa atcatccttg agtcaatcaa cgttccagaa ccagttatcc aattgatggt
    18721 tgagccaaaa tctaaagctg accaagacaa gatgggtatc gcccttcaaa aattggctga
    18781 agaagatcca acattccgcg ttgaaacaaa cgttgaaact ggtgaaacag ttatctcagg
    18841 tatgggtgaa cttcaccttg acgtccttgt tgatcgtatg cgtcgtgagt tcaaagttga
    18901 agcgaacgta ggtgctcctc aagtatctta ccgtgaaaca ttccgcgctt ctacccaagc
    18961 acgtggattc ttcaaacgtc agtctggtgg taaaggtcaa ttcggtgatg tgtggattga
    19021 atttactcca aacgaagaag gtaaaggatt cgaattcgaa aacgcaatcg tcggtggtgt
    19081 ggttcctcgt gaatttatcc cagcggttga aaaaggtttg gtagaatcta tggctaacgg
    19141 tgttcttgca ggttacccaa tggttgacgt taaagctaag ctttatgatg gttcatatca
    19201 cgatgtcgac tcatctgaaa ctgccttcaa gattgcggct tcactttccc ttaaagaagc
    19261 tgctaaatca gcacaaccag ctatccttga accaatgatg cttgtaacaa tcactgttcc
    19321 agaagaaaac cttggtgatg ttatgggtca cgtaactgct cgtcgtggac gtgtagatgg
    19381 tatggaagca cacggtaaca gccaaatcgt tcgtgcttac gttccacttg ctgaaatgtt
    19441 cggttacgca acagttcttc gttctgcatc tcaaggacgt ggtacattca tgatggtatt
    19501 tgaccactac gaagatgtac ctaagtcagt acaagaagaa attattaaga aaaataaagg
    19561 tgaagactaa tccgtcctca ctctagaagg aagtcactta gtggcttcct tttgtcttta
    19621 gaaaatacct ctaaatatgg taaaatagta gaagaataat gtgaggaaaa tgaatgtcaa
    19681 atagttttga aattttgatg aatcaattgg ggatgcctgc tgaaatgaga caggctcctg
    19741 ctttagcaca ggccaatatt gagcgagttg tggttcataa aattagtaag gtatgggagt
    19801 ttcattttgt attttctaat attttaccga ttgaaatctt tttagaatta aagaaaggtt
    19861 tgagcgaaga attttctaag acaggcaata aagctgtttt tgaaattaag gctcggtctc
    19921 aagaattttc aaatcagctc ttgcagtcct actataggga ggctttctct gaaggtccat
    19981 gtgctagtca aggttttaag ttcctttatc aaaatttgca agttcgtgct gagggtaatc
    20041 agctatttat tgaaggatct gaagcgattg ataaggaaca ttttaagaag aatcatcttc
    20101 ctaatttagc taaacaactt gaaaagtttg gttttccaac ttttaactgt caagtcgaga
    20161 agaatgatgt cctgacccaa gagcaggaag aggcctttca tgctgaaaat gagcagattg
    20221 ttcaagctgc caatgaggaa gcgctccgtg ctatggaaca actggagcag atggcacctc
    20281 ctccagcgga agagaaacca gtctttgatt ttcaagcgaa aaaagctgca gctaaaccca
    20341 agctggataa ggcggagatt actcctatga tcgaagtgac gacagaggaa aatcgtctgg
    20401 tatttgaagg ggttgttttt gatgtggagc aaaaagtgac tagaacaggt cgtgttttaa
    20461 tcaactttaa aatgacggac tatacttcaa gtttttctat gcaaaagtgg gttaaaaacg
    20521 aggaagaggc ccagaagttt gacctcatca agaagaattc ttggctccga gttcgaggga
    20581 atgtggagat gaataacttc acacgcgatt tgactatgaa cgtacaggat ctgcaggaag
    20641 ttgttcacta tgagcggaag gatttgatgc cagaaggtga gcgtcgggtt gagtttcatg
    20701 ctcatactaa catgtcgact atggatgctt tgccagaggt cgaagagatt gttgcaacag
    20761 ctgctaagtg gggacacaag gcggttgcta tcacagacca tgggaatgtc cagtcctttc
    20821 cacatggcta taaggcggct aagaaagcgg gaatccagct gatctatggg atggaagcca
    20881 atatcgtgga ggaccgtgtc cctatcgtct ataacgaagt ggagatggac ttatcagaag
    20941 caacctacgt ggtctttgac gtggaaacga cgggactttc agctatctat aatgacttga
    21001 ttcaggttgc ggcctctaag atgtacaagg ggaatgttat tgctgaattt gatgaattta
    21061 tcaatcctgg gcatcccttg tcagctttta ctacagagtt aactggaatt acagatgatc
    21121 atgtcaaaaa tgccaaacca ctagaacaag ttttgcaaga attccaagaa ttttgcaagg
    21181 atacggtcct agttgcccac aatgctacct ttgacgttgg ctttatgaat gctaattatg
    21241 agcgtcatga tcttccaaag attagtcagc cagttattga tacgctggag tttgctagaa
    21301 acctctatcc tgagtataaa cgccatggtt tggggccttt gaccaagcgt tttggtgtgg
    21361 ccttggaaca tcaccacatg gccaactacg atgcggaagc gactggtcgt ctgcttttca
    21421 tctttatcaa agaggtagca gaaaaacatg gtgtgaccga tttagctaga ctcaacattg
    21481 atctaatcag tccagattct tacaaaaaag ctcggatcaa gcatgcgacc atctatgtca
    21541 agaatcaggt aggtctaaaa aatatcttta agctggtttc cttgtctaat accaagtatt
    21601 ttgaaggagt gccacggatt ccgagaacgg ttctagatgc ccatcgagag ggcttgattt
    21661 taggttcagc ctgttcagag ggtgaagttt ttgacgtggt cgtttctcaa ggtgtggatg
    21721 cggcggttga ggtggccaag tattatgact ttatcgaggt catgccaccg gctatctatg
    21781 cgcccttgat tgccaaagag caggtcaagg atatggagga actccagacc attatcaaga
    21841 gtttgataga ggttggagat cgccttggca agcctgttct ggctacggga aatgttcact
    21901 atatcgaacc ggaagaagag atttatcgtg aaattatcgt ccgtagtttg ggacagggtg
    21961 cgatgattaa ccgaactatc ggtcatggtg aacatgccca accagcgcca cttccaaagg
    22021 ctcattttcg aacgactaat gagatgttgg atgaatttgc ctttttggga gaggaactgg
    22081 ctcgtaaact ggttattgaa aacaccaatg ccttggcaga aatatttgaa cccgttgaag
    22141 tcgttaaggg tgacttgtat acgcctttca tcgacaaggc tgaagaaaca gttgctgagt
    22201 tgacctataa gaaagctttt gagatttatg gaaatccgct gccagatatt gttgatttgc
    22261 ggattgaaaa agaattaaca tccatactgg ggaatggatt tgctgtgatt tatctggcat
    22321 cgcagatgct ggtgcaacgt tctaatgaac ggggttattt ggttggttct cgtgggtctg
    22381 tcggatctag tttcgttgcg accatgattg ggattacgga ggtcaatcct ctctctcctc
    22441 actatgtctg tggtcagtgt cagtacagtg agtttatcac agatggttcg tacggttcag
    22501 gatttgatat gccccataag gactgtccaa actgtggtca caaactcagt aaaaacggac
    22561 aggatattcc gtttgagacc ttccttggtt ttgatgggga taaggttcct gatattgact
    22621 tgaacttctc gggagaagat cagcctagcg cccacttgga tgtgcgtgat atctttggtg
    22681 aagaatatgc cttccgtgcg ggaacggttg gtacggtagc tgccaagact gcctatggat
    22741 ttgtcaaggg ttacgagcga gattatggca agttttatcg tgatgcagaa gtagaacgcc
    22801 tcgctcaagg agcggcgggt gtcaagcgga caacaggcca acacccgggg ggaatcgttg
    22861 ttattccgaa ctacatggat gtctacgatt ttacgcctgt ccagtatcca gcagatgatg
    22921 tcacggctga atggcagacc actcacttta acttccacga tatcgatgag aacgtcctca
    22981 aactcgatgt actgggacat gatgatccga ccatgattcg aaaacttcag gatttgtctg
    23041 gtattgaccc taataaaatt cctatggatg acgaaggcgt gatggcactc ttttctggga
    23101 ctgatgtact aggggtaaca cctgaacaaa ttggaacgcc tacgggtatg ttggggattc
    23161 cagagtttgg aacaaatttc gtacgtggaa tggtagacga aacccatccg acaacctttg
    23221 cggaattgct tcagctgtct ggtctgtccc acggtactga cgtttggttg gggaatgctc
    23281 aggatctgat taagcaagga atagcagacc tatcgactgt tatcggttgt cgggacgaca
    23341 tcatggttta cctcatgcat gcgggtctgg aacctaagat ggcttttacc attatggaac
    23401 gggtacgtaa gggtttgtgg ctaaagattt cagaagagga gagaaatggc tatatcgaag
    23461 ccatgaaggc taataaggtg ccagagtggt atatcgaatc ctgtgggaaa attaagtaca
    23521 tgttccctaa ggcccatgcg gcagcctacg ttatgatggc cttgcgtgta gcttacttca
    23581 aggttcacca tcctatttat tactactgtg cttacttctc cattcgtgct aaggcttttg
    23641 atatcaagac catgggtgcg ggcttggagg tcatcaagcg cagaatggaa gaaatctctg
    23701 aaaaacggaa gaacaatgaa gcctctaatg tggaaatcga tctctataca actcttgaga
    23761 ttgtcaatga gatgtgggaa cgaggtttca agtttggtaa attagatctc taccgtagtc
    23821 aggcgacaga gttcctcatc gacggggata cccttatccc accatttgta gcaatggatg
    23881 gtctgggaga gaacgttgcc aagcaactgg tgcgggcgcg tgaagaggga gaattcctct
    23941 ctaaaacaga actacgcaag cgtggtggac tctcatcaac cttggttgaa aagatggatg
    24001 agatgggtat tcttggaaat atgccagagg ataaccagtt gagtttgttt gatgagttgt
    24061 tttaaaaaat tgcttaataa tctattaaaa gaggctaacg tatatccaat agatttacat
    24121 tagctttctt ttttgttaaa atagtctatg gaaagagggt gagagtatgt caaagatgag
    24181 tataagcatc cgtctggata gtgaggttaa ggagcaggcc caacaggtgt ttagtaatct
    24241 gggaatggat atgacaacag ctattaatat tttccttcgt caggcaattc aatatcaggg
    24301 attacctttt gatgttagac tagacgaaaa tcggaagttg ctccaagcgt taacggattt
    24361 agaccaaaat cgtaatatga gccagtcttt tgaatcagtc tcagatttga tggaggactt
    24421 acgtgcttaa gattcgttat cataaacagt ttaaaaaaga ttttaagttg gctatgaagc
    24481 gtggtttgaa ggcagaatta ttagaagaag ttttgaattt tctggttcaa gaaaaagaac
    24541 atcctgccag atatcgtgat cattcattga cggcatccaa gcattttcaa ggagttcgtg
    24601 aatgccatac ccagccagat tggcttttgg tttataaagt agacaagtcg gaattgattt
    24661 taaatttgct gaggacaggc agtcacagtg atttatttta atctatttta agggggttct
    24721 catgaaacta agaatatttg cggaagataa gccggctaag aaggtatttg aatatcaatt
    24781 agaacttgct gatcgtacaa ttcttctatc gacagcactc ttgtcaggtg ctattgcttt
    24841 agcaggaatc ttttctgctt tgaaagaaaa ataaaaatag aaaagagaaa acagaatggt
    24901 tttaccaaat tttaaagaaa atctagaaaa atatgcgaaa ttgttggttg cgaacggaat
    24961 taacgtgcaa cctggtcaca ctttggctct ctctattgat gtggagcaac gtgaattggc
    25021 acatctaatc gtgaaagaag cttatgcctt gggtgcgcat gaggtcatcg ttcagtggac
    25081 agatgatgtg attaaccgtg agaaattcct ccatgccccg atggagcgtt tggacaatgt
    25141 gccagaatac aagattgctg agatgaacta tcttttggag aacaaggcta gccgtcttgg
    25201 ggttcgttca tctgatccag gtgccttgaa cggagtggac gctgacaagc tttcagcttc
    25261 tgctaaagct atgggacttg ccatgaagcc aatgcgaatc gcaactcaat ctaacaaggt
    25321 tagctggact gtagcagccg ctgctggact tgagtgggct aagaaagtct tcccaaatgc
    25381 tgcgagcgac gaagaagcag ttgatttcct ttgggatcaa atcttcaaaa cttgtcgtgt
    25441 ctacgaagca gatcctgtta aggcttggga ggaacatgca gccattctca agagcaaggc
    25501 cgatatgctt aataaggagc aattttcagc ccttcactac acagcgccag gaacagattt
    25561 aacacttggt ttgccaaaga accacgtttg ggaatcagct ggtgctgtca atgcacaggg
    25621 cgaagaattc ttgccaaata tgccgacaga agaggtcttc acagcgcctg acttccgtcg
    25681 tgcagatggt tatgtcactt ctacaaaacc gcttagctac aacggaaata tcattgaagg
    25741 cattaaggtg acctttaagg atggacaaat cgtagatatc actgctgaga agggtgatca
    25801 ggttatgaaa gaccttgtct ttgaaaatgc gggtgcgcgt gccttgggtg aatgtgcctt
    25861 ggtaccagat ccaagtccaa tttctcagtc aggcattatc ttctttaaca cccttttcga
    25921 tgaaaatgcg tcaaaccact tggctatcgg tgcagcctat gcgactagcg ttgttgatgg
    25981 agcggagatg agcgaagagg agcttgaagc tgcagggctt aaccgttcag atgttcacgt
    26041 agactttatg attggttcta accaaatgga tatcgatggt attcgtgagg atggaacgcg
    26101 ggtacctctt ttccgtaatg ggaattgggc aaattaagga gataatatgt taggaagtat
    26161 gttcgttggt ctcctagtgg gatttttagc aggtgctatg accaatcgtg gagagcgaat
    26221 gggatgtttt ggaaaaatgt ttctcggttg gatcggagcc tttctaggtc acttgctctt
    26281 tggaacttgg gggccagttt tatcaggaac agctattatc ccagcgattt taggagccat
    26341 gattgtttta gctatttttt ggagacgagg aagttaattt cctaaatctg atactcaatg
    26401 aaaatcaaag agcaaactag gaaactagcc gcaggttgct caaagcactg ctttgaggtt
    26461 gcagatagaa ctgacgaagt cagtaacata tatacggcaa ggcgacgttg acgcggtttg
    26521 aagagatttt tgaagagtat gaaacgaaaa ggaggttggt cattgtacca gcctcctttt
    26581 gatatgatat aatagttcta tgagattaga taaattttta gttgcctgtg cggtgggaag
    26641 tcggactgag gtcaaaaact tgctcaaggc tgggcgcgtg actgtaaatg gtaaaaaaga
    26701 aaaatcagct aaattgcaga ttgatgaaaa aatagatgag attcgctttg atgggcaagt
    26761 gttggagtat gaagagtttg tctactacat gatgaacaag cccaaaggag ttatctcagc
    26821 gactgaggat cccaagcaca gaaccgttct ggacttgttg gatgacttgg cgcggagtaa
    26881 ggaagttttc ccagtaggac gcttggatat tgacacgcat ggtcttttgc tcttgaccaa
    26941 tgatggtcag ctggctcatg ttcttctttc gcccaagcgt catgtggata agacttatct
    27001 ggcacaagtc aagggaatca tgacccaaga agatgtggag acatttgctg agggtattcc
    27061 tctcaaagac tttacctgtc aacccgctat actggagctt gtatccatag atacagaaaa
    27121 gaatcagagc caaatccgtg tgaccattgc agaagggaag tttcatcaga tcaagcgtat
    27181 ggtgggctac tgtggcaagg aagtggtgga cttgcaacga ttgactatgg gaactttagt
    27241 attagatgag aacctggaac gaggggaatg gcgtcgcttg accaaggaag aattagaaat
    27301 tctccgcgct aatattattt aatttagttt aatactcaat gaaaatcaaa gagcaaacta
    27361 ggaaactagc cgcaggctgt acttgagtac ggcaaggcga cgttgacgtg gtttgaagag
    27421 attttcgaag agtataaatt cgaaaaaggt gagggagaat gtccttacct tttatgtttt
    27481 ttagttgctt cctttgtgaa aagagttata atagactgta gaataaaagg aggaatctat
    27541 gaacgcgatt caagaatcat ttactgataa actatttgcc aactatgaag caaatgtaaa
    27601 ataccaagcg attgaaaatg ctgccagcca caacggaatt tttgcagctc tggaacgtcg
    27661 ccaaagccat gtagacaaca cacctgtttt ctcattggat ttaaccaagg acaaggtcac
    27721 taaccagaaa gcgtctggtc gttgctggat gtttgcggct ctcaacacct tccgccacaa
    27781 actcatctcg caatacaaat tggagaactt tgagttgtca caagcccaca ctttcttctg
    27841 ggataagtat gagaaatcaa actggttctt ggagcaagtc attgcgactt cagaccaaga
    27901 attgactagc cgcaaggtta gcttcttact ccaaacacct caacaagatg gtggtcaatg
    27961 ggatatggtc gtttccctct ttgaaaaata cggtgtcgtg cctaagtcag tttatcctga
    28021 gtctgtttca tctagcagca gtcgtgagct aaatgcgatc cttaataaat tgcttcgtca
    28081 agatgctcaa atcttgcgtg atttgcttgt ttctggtgca gatcaagtga ctgttcaagc
    28141 taagaaagaa gacctcttgc aagaaatctt taactttctt gctatgtcat taggacttcc
    28201 accacgcaag tttgactttg cttatcgcga taaagataac aactacaaaa gtgaaaaagg
    28261 aatcacacca caagagttct acaagaaata tgtcaatctt cctttagaag actacgtttc
    28321 tgttatcaat gctccaactg ctgataaacc ttacggaaaa tcttacacag ttgagatgtt
    28381 ggggaatgtg gttggtagcc gtgcagttcg ttacatcaac gttccaatgg agcgcttgaa
    28441 agaattggcg attgcccaaa tgcaagcagg tgagactgtt tggtttggtt ctgatgtcgg
    28501 ccagctcagt aaccgtaagg ctggaatcct tgcgacagat gtttatgact ttgaatcaag
    28561 catggacatt aaacttactc aagacaaggc tggacgtttg gactatagcg aaagcttgat
    28621 gacccacgcc atggtcttga caggtgttga cttggacgaa aatggtaaat caaccaagtg
    28681 gaaggttgaa aactcatggg gagacaaggt cggtacagat ggttactttg ttgcctcaga
    28741 cgcttggatg gacgaataca cataccaaat cgttgttcgt aaggaattgc tgacagcaga
    28801 agaacaagct gcctatggag cagaaccaat tgtacttgca ccatgggatc caatgggagc
    28861 cttggctaaa taaaagcata gaaaaaagga atcagatttt agaacctggt tcctttttag
    28921 ttgcttgatt acatgatgtg aagaacatgt gccacaatac ccactgcgaa gagggcaagg
    28981 ataatagtga ttggagatac ttttttctta agtaagtaca tgcaaagtaa agtaaggagt
    29041 agtcctgata atccaggaat caacatatcc aagttttgtt ggaaagtagt aactttttca
    29101 ggagtttgag acaatccttg tcctacttgt gcgaatgctt cttggatacc tttagaccct
    29161 tctggcaatt tatcccaatg gatataagcc ttttcatcta gttgaacttt agaaacatcg
    29221 aaagcaaatt taatatttac ccagcgttga acaaggacag caagaatgaa catcccaagg
    29281 atagaagctc ctttagtgat atcttgaagg ataccaccag acatatcttt agtgatttct
    29341 gatccagcct tgtatccaat ctcttgaaca taccacaaga atgacatacg aatcaagttc
    29401 catgcaacaa agaagaggag tggccccaag atattgccag taagggcaag tgaagcaccg
    29461 agagatccaa ggattgggcg tactgtaaac cagaatactg ggtcaccgat accagcaaga
    29521 ggtcccatca taccgatttt aaccccttgg atagcagcgt catcgatttc cacaccgtta
    29581 gcacgttctt cttcaagcgc aagagtaacc cccatgactg gagcagctac gtatggatga
    29641 gtgttgaaga actcaaggtg acgctcaaga gcagcgattt gatcttcttt tttagtatag
    29701 agttttttga tagctggaat gagtgtataa gcccagccca agttttgcat ccgttcaaag
    29761 ttccaagacc cttgtaagaa ggttgaacgc caccaaactt ttttacgatc tgatttagtt
    29821 aattgaagtt tttcagtcat gatgttttca gtcctttctt atcttagtag tcttctagga
    29881 tatcgccgat tgggtcgtta gaagttgcgg ctcctccgcc accatttcca ccagttttag
    29941 aaaggtgaag gtagataaga gcgatagcaa caccgatagc accgaatccg attagagtaa
    30001 tatctgacac agcagcgaga acgaaaccaa gagcgaagaa tggccatact tcacgagttg
    30061 ccatcatgtt gataaccatg gcgtaaccaa cggcaacgac cataccacca ccgatagcca
    30121 taccatcttt gagccagtct ggcatggcac taaggatact ttgtacagtt tcagttggta
    30181 ccataaggag aagagctgca ggaagcgcga tacgaagtcc ttggaaaagt agcgcaatga
    30241 aatgcgcacg ctccacagcg ccgaagtcac cttttttagc ggcagcatct gcagtatgaa
    30301 ccaaaccaac tgaaattgta cgaacaatca ttgtcaagaa aagtccagct acggcaagag
    30361 ggatagcaac cgcttgggca acaccgatac cagtcttggt aaagtcacca ccaagaacca
    30421 tgataatggc agcagcgaca gaagcaagtg cagcatcagg agcgatagca gcaccgatat
    30481 ttgaccaacc aagggcaatc atttgaagcg atccaccgag gataatccct gcttccaagt
    30541 gacctgttac aagcccaata agggtacagg ctacaagtgg ttggtgaaat tggaactggt
    30601 cgaggatgcc ttcaagacct gcaaagaagg ctacaacgat tactaaaacc atagaaataa
    30661 tagacatgtt taaaatcctt tcataaataa tggcttattt gacattggct ttgttaatca
    30721 agtcaaacaa atctttttta gaatcatttg gtactttacg gacatcaaat tcaacaccca
    30781 agtcacgcat tttttcaaat gtagcaacat cttctttgtc catagacaaa acggtattga
    30841 ccaatgtttt acctgttgag tgagccatag aaccaacgtt aagagtcttg attggcacgc
    30901 cgccttcgat ggcacgaagg gcatcttgag gtgtttcaaa caagataagg gcatgtgttt
    30961 ctccaaaacg tgggtctttt gaaatctcaa tcagtttttg aattggaacc acgttagcct
    31021 tgacattacc tggagctgct tgtttaatca attctttacg aaggtcgtct ttagccacgt
    31081 tatctgaagc aacgatgata cgatttgctt ttgaatctgg agtccaagca gttgcaacct
    31141 gaccgtgaag tagacgtgtg tcaagacggg caagattgat tttcaattta ccgtctccga
    31201 taacagttcc ttctgggata gcagtttggg caactggagc agctgcagcg cttgcaactt
    31261 cttcaactgg atttagctct tctggaagag ctttgatgcc atctttggct tctttaatga
    31321 tattagcagc gactttttct acacctgcag cagcgtccat gaggcgctct gtgtaggctt
    31381 gaatcaacat cggtaagtta agtcctgtga tgatggcaaa cttacgctca ggattttctc
    31441 ccatcacgcg actagcttgg ttaaatggag aaccactcca aaggtcagcc aaaactagaa
    31501 cctcatcttc tgcgtcaaat gcagcaacag cgttattaaa cttagcgtat agatcatcag
    31561 gaccttcatt tggcataaag gtcacaactt gaaccttttc ttgttcacca aagatcatag
    31621 atcctgactg atgaatacca gcagcaaatt cgccgtggct cgcaataatg attccgatac
    31681 tcattattgt cattcctcct tttttgtttt agttttcatt taagaaaact ttaagactgt
    31741 ttaagtataa accgttttca taaaaa
//
LOCUS       DAVLDI010000022        31553 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLDI010000022 DAVLDI010000000
VERSION     DAVLDI010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31553
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.022"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..338)
                     /locus_tag="VXD01_001018"
     CDS             complement(<1..338)
                     /locus_tag="VXD01_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0601440.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIIKKDTHKEIIAKLDYEAPSCP
                     ECGSQMKKYYFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKIMVAETSIVKKNHQI
                     PRIINQKIAQ"
     gene            complement(493..1203)
                     /gene="treR"
                     /locus_tag="VXD01_001019"
     CDS             complement(493..1203)
                     /gene="treR"
                     /locus_tag="VXD01_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV0601441.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            1388..3355
                     /gene="treP"
                     /locus_tag="VXD01_001020"
     CDS             1388..3355
                     /gene="treP"
                     /locus_tag="VXD01_001020"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV0601442.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFVYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            3533..5158
                     /gene="treC"
                     /locus_tag="VXD01_001021"
     CDS             3533..5158
                     /gene="treC"
                     /locus_tag="VXD01_001021"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV0601443.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            5414..5662
                     /locus_tag="VXD01_001022"
     CDS             5414..5662
                     /locus_tag="VXD01_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV0601444.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            5869..6663
                     /gene="racE"
                     /locus_tag="VXD01_001023"
     CDS             5869..6663
                     /gene="racE"
                     /locus_tag="VXD01_001023"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV0601445.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            6660..7631
                     /locus_tag="VXD01_001024"
     CDS             6660..7631
                     /locus_tag="VXD01_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV0601446.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            7607..8128
                     /locus_tag="VXD01_001025"
     CDS             7607..8128
                     /locus_tag="VXD01_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0601447.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            8125..8586
                     /locus_tag="VXD01_001026"
     CDS             8125..8586
                     /locus_tag="VXD01_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0601448.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            8577..9317
                     /gene="xerD"
                     /locus_tag="VXD01_001027"
     CDS             8577..9317
                     /gene="xerD"
                     /locus_tag="VXD01_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV0601449.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            9317..10045
                     /locus_tag="VXD01_001028"
     CDS             9317..10045
                     /locus_tag="VXD01_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV0601450.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            10064..10633
                     /locus_tag="VXD01_001029"
     CDS             10064..10633
                     /locus_tag="VXD01_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV0601451.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            10620..11342
                     /locus_tag="VXD01_001030"
     CDS             10620..11342
                     /locus_tag="VXD01_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV0601452.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            11342..11584
                     /gene="yidD"
                     /locus_tag="VXD01_001031"
     CDS             11342..11584
                     /gene="yidD"
                     /locus_tag="VXD01_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV0601453.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(11809..12774)
                     /locus_tag="VXD01_001032"
     CDS             complement(11809..12774)
                     /locus_tag="VXD01_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0601454.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(12870..13622)
                     /locus_tag="VXD01_001033"
     CDS             complement(12870..13622)
                     /locus_tag="VXD01_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601455.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(13619..14575)
                     /locus_tag="VXD01_001034"
     CDS             complement(13619..14575)
                     /locus_tag="VXD01_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV0601456.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(14565..15524)
                     /locus_tag="VXD01_001035"
     CDS             complement(14565..15524)
                     /locus_tag="VXD01_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0601457.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKCYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(15821..15931)
                     /locus_tag="VXD01_001036"
     CDS             complement(15821..15931)
                     /locus_tag="VXD01_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEV0601458.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            complement(15947..16648)
                     /locus_tag="VXD01_001037"
     CDS             complement(15947..16648)
                     /locus_tag="VXD01_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEV0601459.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLKENQIDAVLHYAGEIVVSESIENPSKYFTANVAGRNQV
                     LKVLSEVGTQKIMFSSTASLYGNNCIDKPATEDTLIDPVNPYTETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            17048..18112
                     /gene="pepA"
                     /locus_tag="VXD01_001038"
     CDS             17048..18112
                     /gene="pepA"
                     /locus_tag="VXD01_001038"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV0601460.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            18134..18430
                     /locus_tag="VXD01_001039"
     CDS             18134..18430
                     /locus_tag="VXD01_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0601461.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            19112..19555
                     /locus_tag="VXD01_001040"
     CDS             19112..19555
                     /locus_tag="VXD01_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0601462.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            19559..20323
                     /locus_tag="VXD01_001041"
     CDS             19559..20323
                     /locus_tag="VXD01_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV0601463.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            20338..21066
                     /locus_tag="VXD01_001042"
     CDS             20338..21066
                     /locus_tag="VXD01_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601464.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            21059..22579
                     /locus_tag="VXD01_001043"
     CDS             21059..22579
                     /locus_tag="VXD01_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV0601465.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALMAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            22924..23730
                     /locus_tag="VXD01_001044"
     CDS             22924..23730
                     /locus_tag="VXD01_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV0601466.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(23897..24433)
                     /locus_tag="VXD01_001045"
     CDS             complement(23897..24433)
                     /locus_tag="VXD01_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0601467.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIINLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            24566..25456
                     /locus_tag="VXD01_001046"
     CDS             24566..25456
                     /locus_tag="VXD01_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV0601468.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     VSLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            25700..26053
                     /locus_tag="VXD01_001047"
     CDS             25700..26053
                     /locus_tag="VXD01_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV0601469.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            26054..27091
                     /locus_tag="VXD01_001048"
     CDS             26054..27091
                     /locus_tag="VXD01_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0601470.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAVTTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(27137..28144)
                     /gene="galR"
                     /locus_tag="VXD01_001049"
     CDS             complement(27137..28144)
                     /gene="galR"
                     /locus_tag="VXD01_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV0601471.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            28309..29487
                     /locus_tag="VXD01_001050"
     CDS             28309..29487
                     /locus_tag="VXD01_001050"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV0601472.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            29506..30987
                     /locus_tag="VXD01_001051"
     CDS             29506..30987
                     /locus_tag="VXD01_001051"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV0601473.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQAAFMRFVEQVGISLD"
     gene            31057..31461
                     /locus_tag="VXD01_001052"
     CDS             31057..31461
                     /locus_tag="VXD01_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV0601474.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGRRSEDRQVRI"
BASE COUNT         8948 a         5966 c         7419 g         9220 t
ORIGIN      
        1 ttttgagcaa tcttttggtt gatgatacga gggatttggt gattcttctt gacgatagaa
       61 gtttcagcaa ccataatttt agaacaatga tagcacttga aacgacgctt tctaaggaga
      121 attctagtag gcataccagt tgtttcaaga taaggaattt tagaaggttt ttgaaagtaa
      181 tatttcttca tttgacttcc gcactcagga caagatggag cttcatagtc cagtttggcg
      241 atgatttcct tgtgtgtatc cttcttgatg atgtctaaaa tctggatatt agggtcttta
      301 atgtctagta attttgtgat aaaatgtaat tgttccatat gattctttct aatgagttgt
      361 tttgtcgctt ttcattatag gtcatatggg actttttttc tacacaaaat aggctccata
      421 atatccatag gggggttacc cactacaaat attatagagc cgaaaaaggc tgagatctgg
      481 tgtctcagtc ttttatttct tgcgttttgc aaaatctaca aatctaaatt tttctaactt
      541 atggcgactt tcggtaaact gaaattggcg tccgtcttgg agatagactt ttgatttaat
      601 cgaaacgaca taagggtctt tgccaatgtc catgagaatc ttgtctcggt cgcttgagtg
      661 gtcaatggtg atttccttct gagcataatc aataaggagt ttgaggccat tttctatata
      721 agaatagata gactgctcag caatttggcg agtgagattt ggaattagtt ccatatccag
      781 atagtctgta tccagaacgg ataccagatc atccaccaca cgctggcgga ccaccttcca
      841 aaccatccga aactctggga aaccggttat cagtgaggat tttttatcaa taataatctt
      901 gtccagactg accacgttgg ttttagagcg cagtccaagt tctttaacta gttcttggta
      961 gctggttagg ttggatacag ggaaattgac ggtttcttct ttgacgactt gagaaccttg
     1021 ccctcttatc tttttgatca atccttcctc ttggaggaga gacagggcct ttcggacggt
     1081 atcacgactc acttgatatt gctccataag gtcgtgctcg ctaggaagga aatctccgac
     1141 agcgtaagtc tcgttttgaa tggtttcttg gatttgctta aataattgtt ggtatttctt
     1201 cattttgcct gcttaaatag gtttttagtc tagtttaatg aacacctgta tctattttac
     1261 catacaagtg ctagaaaatt tacaaaaaaa cacccttttt ataccaaaca agttgcagac
     1321 aagtttggta tcgtttacaa tatacttatc aaatcaaact tgctttgaca agtataagga
     1381 gaatcaaatg ggaaaatttg aacaagaagc caaagatctg cttcaggcaa ttggaggcaa
     1441 agaaaatgtg actgccgtca cccactgtgc gacacggatg cgctttgttt taggagatga
     1501 taagaaggct aatgttaaag ctatcgagtc aattccagct gttaaaggaa cttttacaaa
     1561 tgcaggtcaa tttcaggtaa tcattggaaa tgacgtgccc atcttttata atgattttac
     1621 agccgtttca ggtattgagg gtgtttccaa agaagcagcc aagtctgcag ctaagagtaa
     1681 tcaaaacgtg gtccaacgtg ttatgaccac tctggcggag atttttactc cgattattcc
     1741 agccttgata gtcggaggat tgatcctcgg tttccgtaat gtcttggaag gtgtccattg
     1801 gtcgatgttg gatggcaaga ccatcacaga atcctctcag ttttgggcag gtgtcaatca
     1861 cttcctctgg ttgcctggtg aagctatctt ccagttctta ccagtaggga ttacttggtc
     1921 tgtttctcgt aagatgggaa ccagccaaat tttgggaatt gttctcggaa tctgtttggt
     1981 atcgcctcag ttgctcaatg cctatgcggt tgcttcaacg ccagcagctg atatcgcggc
     2041 aaactgggtt tggaattttg gctattttac tgttaatcgt atcggttacc aagcccaagt
     2101 tatcccagcc ttgcttgcag gtttgagtct gtcttatctt gaaatcttct ggcgcaagca
     2161 tatcccagaa gtcatttcta tgatttttgt acctttcttg tcattgattc cagccttgat
     2221 tttggctcat actgttttgg gaccaatcgg ttggacaatt ggacaaggac tttcatcagt
     2281 tgtcttggca ggtttaactg gtccagttaa atggctcttc ggtgcaattt ttggtgccct
     2341 ctacgctcca tttgtcatca caggtctgca ccatatgacc aatgccattg atacacaatt
     2401 gattgcggat gctggtggca ctgccctatg gccaatgatt gctctttcta atattgctca
     2461 aggctcagcc gtgtttgtct attatttcat gcatcgccat gatgagcgtg aggctcaggt
     2521 ttcacttcct gcaaccattt cagcctatct cggtgttaca gaaccagctc tttttggggt
     2581 taacgtaaaa tatatttatc catttgttgc tgggatgact ggttcagccc ttgcaggcat
     2641 gttatccgtt acttttaatg taactgcggc ttctattggt atcggtggtt tgccaggtat
     2701 tctctctatt caacctcaat acatgctgcc atttgcagga actatgctag ttgcgattgt
     2761 tgttccaatg ctcttgactt tcttcttccg caaggctggt ctctttacaa aaacagaggg
     2821 cgatacgaac ttgcaggcag aattcgttgc tcaagaagaa gcagaatttg tgaaccatga
     2881 accagtagaa cttacttcgg tagaaattat cagcccacta actggccaag tgaaagaatt
     2941 gagtcaagcg acggatccta tttttgcatc aggtgtcatg gggcaaggtc tagtcattga
     3001 accaagccaa ggtgagttga cctctccagt taatgggaca gtgacggttc ttttccctac
     3061 caagcatgcc atcggcattg tctctgacga gggagttgaa ttgctcatcc acatcggtat
     3121 ggatacagta ggtcttgatg gcaaaggttt tgaaagtctt gtagtccaag gagatcacgt
     3181 tacagttggt cagcaactga ttcgttttga tatggatgtc attaaggctg caggtctggt
     3241 gacagaaact cctgttatca tcaccaacca agatgcttat acagcgacta ttcccggaac
     3301 ttatccgaca acgatccaag ctggagcatc tctcatggtc gctacacgaa tctaatactc
     3361 ttcgaaaatc tcttcaaacc acgtcagctc tatctgcaac ctcaaaatag tgttttgagc
     3421 aacctgtggc tagcttccta gtttgttctt tgattttcat tgagtataat tgaaatagca
     3481 caaataggga cggaagactg cttcctccct tttatcagaa aaggagaaac agatgacact
     3541 tgataaagga aaagtagtct atcaaatcta tccaaaatct tacaaagaca ccactgaaaa
     3601 cggtattggg gatttccgtg ggattatcga aaaaattccc tatttagcca aactaggtgt
     3661 ggatatggtc tggctcaatc cattctatcc aagccctcaa cgggataatg gttacgatat
     3721 ttcagattat atggcagtgg atcctctttt tggtgatatg gctgattttg aggaaatggt
     3781 gtgtgtcggt aaagagcaca agattgactt tatgctggac atggtactta atcattgttc
     3841 gacagagcat gaatggtttc agaaagccct agctggtgat aagtattatc aagacttttt
     3901 cttcatccaa gaccaaccaa cagattggca gtctaagttt ggtggttctg catggacgcc
     3961 tttcggggat actgggaaat actatcttca cctatttgat gagacccagg ctgaccttaa
     4021 ctggcgcaat tccaatgtcc gtaaggagct tttcaaggtt gttaatttct ggcgcgacaa
     4081 gggtatcaaa ggtttccgat ttgatgtgat caatttgatc ggtaaggacg aggtttcagt
     4141 ggactgtcct gaaaatgaag ggaagccagc ttatacagac aaacccatcg ttcataacta
     4201 tttgcgtatg atgaaccaag ccacttttgg atctgacgat agctttatga cagttgggga
     4261 aatgtcttct accaccatgg aaaactgtgt cctctattcg tcgcctgatc gtcaggaatt
     4321 atccatgacc tttaattttc atcacctcaa ggtggactat aaggatggac aaaagtggac
     4381 cttggctccc tttgattttg aagagttgaa gagtctttac catagttggg gtaaggaaat
     4441 gagtgataaa gacggttgga gtgccctctt ttggaacaat cacgatcaac cacgtgcctt
     4501 gaaccgtttt gtcgatattc aaaacttccg caaggaagga gccaccatgc tagcggctag
     4561 cattcacctg tcacgtggga caccttatat ctatatgggt gaagaaatcg ggatgattga
     4621 cccagactat gattctatgg ctgattatgt ggatgtcgaa tcgcttaatg cctatcagac
     4681 gctcttagaa gaaggaaaga gtcagcaaga agccttccag attattcaag ctaagtcgcg
     4741 tgataattca cgcattccca tgcagtggga tgcttcggaa aatgcaggat tttcaacagg
     4801 cactccatgg ttgaaagctg gtaaatccta taaatacatc aatgtagaaa atgaaatcca
     4861 gggtccgatt ttcaccttct atcaagactt gattcgactg cgtaaggaaa tgccaatcat
     4921 ttcagaagga agttacaaac cagcctttga agatagcaaa caagtctacg cttttgaacg
     4981 ccagtttgag gatcaaaagt tactagtgct caataacttt tatgctaaag aagtggaaat
     5041 cgacttgcca gcagtctacc aaaatggaca gattttgata tcaaactatg aagatgcaga
     5101 agtgtctgag aaaattctac tcaaacccta tcaaacactg gctatttatg taaattaata
     5161 ctcttcgaaa atctcttcaa accgtgtcag ttttatctgc aacctcaaag cggtgctttg
     5221 agcaacctgt ggctagcttc ctagtttgct ctttgatttt cattgagtat aaacttagca
     5281 aggagacctc tttttcagaa aagcagggtt ctttttgctg tctattccat ccctgaaagt
     5341 gtagaacaaa ctggtcaggg tggctagttt gtggtataat gaaagggatt caaaaagaaa
     5401 caggagaaaa atgatggatt tacttttagc aattgtattg attgtgctag cttttctagg
     5461 aggagctctt ggaggaatgt acttggttcg taagcaaatc gaaaaagaat ttgctgacaa
     5521 cccacgtttg aatgctgaag cagttcgtac tcttttgagt gcaaatggtc aaaaaccaag
     5581 cgaagctaag gtacaacaag tttaccacca aatcatccgc caacaaaagg cagcccttgc
     5641 taacaataaa aagaaaaaat aaataaggaa aagtctggga tgaaagttcc agacttctca
     5701 ctatgttggt tatggtttag ggatgagact ttttccttgc attctattga tatttgatta
     5761 tgattaagag agaggtagtt gacattctat caagctgtcg gtcagttcgt tcagtacaag
     5821 gaatcataat gaacgatcaa tcagaaaaaa gactagaaag aagactgtat ggataatcga
     5881 ccaattggtt ttttggattc gggtgtcggg ggcttgaccg ttgtgcgcga gctcatgcgc
     5941 cagcttcccc atgaagaaat cgtctatatt ggagattcgg cgcgggcgcc ctatggcccc
     6001 cgtcctgctg agcaaattcg tgaatatact tggcagctgg tcaactttct cttgaccaag
     6061 gatgtcaaaa tgattgtcat tgcttgtaac actgcgactg cggtcgtctg ggaagaaatc
     6121 aaggctcaac tagatattcc tgtcttgggt gtaattttgc caggagcttc ggcagccatc
     6181 aagtccagtc aaggtgggaa aatcggagtg attggaacgc ccatgacggt acaatcagac
     6241 atataccgtc agaaaatcca tgatctggat cccgacttac aggtggagag cttggcctgt
     6301 cccaagtttg ctcccttggt tgagtcaggt gccctgtcaa ccagtgttac caagaaggtg
     6361 gtctatgaaa ccctgcgtcc cttggttgga aaggtggata gcctgatttt gggctgtact
     6421 cattatccac tccttcgccc tattatccaa aatgtgatgg ggccaaaggt tcagctcatc
     6481 gatagtgggg cagagtgcgt acgggatatc tcagtcttac tcaattattt tgaaatcaat
     6541 cgtggtcgcg atgctggacc actccatcac cgtttttaca caacagccag tagccaaagt
     6601 tttgcacaaa ttggtgaaga atggctggaa aaagagattc atgtggagca tgtagaatta
     6661 tgacaaataa aatttatgaa tataaggatg accaggactg gtatgttggg tcttatagta
     6721 tttttggtgg cgttaacagt ttgagcgact atcagacaga ttttcctctg tttgaattct
     6781 ccaaaatatt tggagatgaa gagtatggtt tcccgctttc agttactgtt ttacgctatg
     6841 gttctaccta ccgtttgttc tcctttgtgg tagatatgct taatcaagaa atgggacgaa
     6901 acttggaagt tattcaacgt catggggccc tgctcttggt tgaaaatggg caactcttgt
     6961 atgtagaatt gcctaaagaa ggggtcaatg ttcatgattt ctttgagaca agcaaagtca
     7021 gagaaacctt gttgattgcg actcgtaacg aaggtaaaac caaggaattc cgagctatct
     7081 ttgataagtt aggctacgat gtggaaaatc ttaatgacta ccctgacctg cctgaagtag
     7141 cagaaacagg tatgaccttt gaggaaaatg cccgccttaa ggcagaaacc atttctcaat
     7201 taacgggcaa gatggttttg gcagatgatt ctggtctcaa agtcgatgtc cttggtggct
     7261 taccaggcgt ctggtcagct cgtttcgcag gtgtgggagc aactgaccgt gaaaataatg
     7321 ccaaactctt gcacgaattg gccatggtct ttgaactcaa ggaccgctcg gctcagttcc
     7381 acacaaccct agtcgtagcc agcccaaata aggaaagttt agttgttgaa gcagactggt
     7441 caggttatat taactttgaa cctaagggtg aaaatggctt tggctatgat cccctcttcc
     7501 ttgtaggaga gacaggtgag tcatcagctg aattaaccct ggaagaaaaa aatagtcaat
     7561 ctcaccgtgc cttagccgtt aagaaacttt tggaggtatt tccatcatgg caaagcaaac
     7621 catcattgta atgagcgatt cccatggcga tagcttgatt gtggaagaag tccgtgatcg
     7681 ctatgtgggc aaagtcgatg ccgtttttca taacggcgat tctgaactac gtccggattc
     7741 tccactttgg gagggcatcc gcgttgttaa agggaacatg gacttctacg ccggctaccc
     7801 agaacgtctg gtgactgagc ttggttcgac caagattatc caaactcatg gtcacttgtt
     7861 tgacatcaat ttcaactttc aaaagttgga ctactgggct caggaggaag aggccgctat
     7921 ctgcctctat ggtcacttgc atgtgccaag tgcttggttg gaaggcaaga tcctctttct
     7981 aaatccaggc tctatcagtc aaccacgagg taccatcaga gaatgtctct atgctcgtgt
     8041 ggagattgat gatagttact tcaaagtgga ctttttgaca cgagatcacg aggtgtatcc
     8101 aggtttgtcc aaggagttta gccgatgatt gccaaggagt ttgagacttt cttgttgggg
     8161 caggaggaaa cttttttgac ccctgctaaa aatctagctg tgttgattga tactcacaat
     8221 gcggatcatg cgaccctctt gctcagtcag atgacctata cccgtgttcc cgttgtgaca
     8281 gatgaaaaac agtttgttgg gacgattgga ctcagagata ttatggctta tcagatggag
     8341 catgacttga gccaagaaat catggcggat acggatatcg ttcatatgac aaaaacggac
     8401 gtagcggttg tttcgcctga tttcaccatt acggaggtct tgcacaagct agtagatgag
     8461 tccttcttac cggttgtgga tgcagagggt attttccaag ggattattac gcgcaagtcc
     8521 atcctcaagg ccgttaatgc cctcttgcat gactttagta aggaatatga gattcgatgc
     8581 caatgagaga caggatttca gcctttttag aggaaaagca gggcttgtct gtcaattcca
     8641 agcagtccta taagtatgat ttggagcaat ttttagacat ggtaggtgag cggatttctg
     8701 agaccagtct caagatttac caagcccagc tagccaatct aaaaatcagc gcccagaagc
     8761 gaaagatttc ggcctgtaac caatttctat actttctcta tcaaaaagga gaggtggaca
     8821 gcttttaccg cttggaatta gccaaacaag ctgaaaagaa gacggaaaag ccagagattc
     8881 tatacctaga ctctttttgg caggaaagcg accatccaga gggccgcttg ctagcgctct
     8941 taatcctaga aatggggctc ttgcccagtg agattttagc catcaaggtt gcggacatca
     9001 atctggattt tcaggtgttg cgaatcagca aggcttccca acggaggatt gtcaccattc
     9061 ccacggcctt gctttcagaa ttggaaccct tgatggggca gacctatctt tttgaaagag
     9121 gagggaaacc ctattctcgt cagtgggcct ttcgtcagtt agaatctttt gtcaaggaga
     9181 aaggttttcc atccttatca gctcaagtct tacgtgaaca gtttattcta agacaaatag
     9241 aaaacaaggt cgatttgtac gaaattgcaa aaaaattagg attaaaaaca gtcctgacct
     9301 tagaaaaata tagataatgg atattaaatt aaaagatttt gaaggacccc tggacttact
     9361 cttgcatctg gtttctaagt accagatgga tatctacgat gtgcccatta cggaagtcat
     9421 cgaacagtat ctagcctatg tctcaaccct gcaggccatg cgtctggaag tgacgggtga
     9481 gtacatggtc atggctagtc agctcatgct gattaagagt cgtaaactcc ttccgaaggt
     9541 agcagaagtg acagacttgg gggatgacct ggagcaggac ctcctctctc aaatcgaaga
     9601 atatcgcaag ttcaagctct tgggtgagca cttggaagcc aagcaccaag aacgggccca
     9661 gtattattcc aaagcgccga cagagttgat ttacgaagat gcggagcttg tgcatgacaa
     9721 gacgaccatt gacctctttt tggctttttc aaatatccta gccaagaaaa aagaggagtt
     9781 tgcacaaaat cacacgacta tcttgcggga tgagtataag attgaggaca tgatgattat
     9841 tgtgaaagaa tccttgattg gacgagatca attgcgcttg caggatttgt tcaaggaagc
     9901 ccagaatgtc caagaggtca tcaccctctt tttggcaacc ctagagttaa tcaaaaccca
     9961 ggagctgatc ctcgtgcaag aggagagttt tggagatatc tatctcatgg aaaagaagga
    10021 agaaagtcaa gtgcctcaaa gctagacttg atagagagga aagatgagta ctttagcaaa
    10081 aatagaagcg ctcttgtttg tagcgggtga agatgggatt cgggtccgcc agttagctga
    10141 actcctctct ctgccaccga caggcatcca gcaaagttta ggaaaattag cccagaagta
    10201 tgaaaaggac ccagattcca gtttggcttt gattgagaca agtggtgctt atagattggt
    10261 gaccaagcct caatttgcag agattttgaa ggaatactct aaggcgccta tcaaccagag
    10321 cttgtctcgg gctgcccttg agaccttgtc cattattgcc tacaaacagc cgattacgcg
    10381 gatagaaatt gatgccatcc gtggggttaa ctcgagtgga gccttggcaa agttgcaggc
    10441 ttttgacctg ataaaggaag acgggaaaaa ggaagtattg gggcgcccca acctctatgt
    10501 gactacggat tatttcctag attacatggg gataaaccat ttagaagaat taccagtgat
    10561 tgatgagctt gagattcaag cccaagaaag ccaattattt ggtgaaagga tagaagaaga
    10621 tgagaatcaa taagtatatt gcccacgcag gtgtggccag taggagaaaa gcagaagagc
    10681 tgattaagca aggcttggtg acggttaacg gccaagtggt gcgtgaacta gcaaccacta
    10741 tcaagtcagg cgacaaggtc gaagttgaag gtcaacctat ctacaacgaa gaaaaggttt
    10801 actatctgct taacaaacca cgcggtgtga tttccagtgt gacagatgat aagggtcgca
    10861 agacggttgt cgacctcttg cccaatgtca aagaacgtat ttaccctgtg ggtcgtttgg
    10921 actgggatac atcaggtgtc ttgattttga ccaatgatgg ggactttaca gacgagatga
    10981 ttcaccctcg taatgagatt gacaaggttt atgtcgcgcg tgttaaaggt gtggccaata
    11041 aggacaatct ccgccccttg acccgtggtc ttgagattga tggtaagaaa accaagccag
    11101 ctgtttatga aattctcaaa gtggacccag tcaaaaatcg ctctgtggtg cagttgacca
    11161 tccatgaagg gcgtaaccat caggttaaaa agatgtttga agctgttggt ctccaagtag
    11221 ataagttgtc tcggactcgt ttcggacacc tagacttgac aggactccgt ccaggagaat
    11281 cccgtcgtct taataaaaaa gaaatcagcc aactacacac catggctgta actaagaaat
    11341 aatgaaacga attttaatag cgcctgtgcg cttttaccaa cgttttatct caccagtctt
    11401 tccaccctct tgtcgctttg agctgacttg ttccaactac atgattcagg ctattgaaaa
    11461 acatggtttt aagggggtat tgatgggctt ggctcggatt ttacgttgtc atccctggtc
    11521 gaaaacaggt aaggaccccg ttccagacca cttttccctt aaacgaaatc aagaagggga
    11581 atgaggtggg gtaaatagat ttcaaaatga taaaaacgca tcctatcagg tttgagtgaa
    11641 cttgatagga tgcgttttag aatgtcaaaa ttttatactc ttcgaaaatc ccttcaaacc
    11701 gcgtcagctt tcatctgcaa cctcaaaaca gtgttttgag caacctgcgg ctagtttcct
    11761 agtttgctct ttgattttca ttgagtatta aattgagttt gaagtggctt atttcaaagc
    11821 tttttgtatg tcttcaatca tgagttttgt tgattcaagt ccgcctccgc ttagatacca
    11881 gaggtctggt gttagttgga taatcttacc atttttagca gcaggtgttt cagcgataag
    11941 ggcattttct aggacaccgt cgttgctaga gttgtcccca ccgatggcaa gggtacggtt
    12001 gatgacaaag aggatgtcag ggttgatttc tttgacactt tcaaagctga cttcttgtcc
    12061 gtggcgtgag tcttcaaatg ttgtatcagt tggtttgaat ttcaaggttt ggtacaagaa
    12121 agagaaacga gatttggcac caaaggctgc catttttcct tcattaagga ggatcgcaag
    12181 ggcctttttg tcagagcttt catttttagt agcgacttct tggatgctct tgtctagctt
    12241 ggccaattct tccttggctt tctgtgtacc agtttcgccg aaggcacttg ctaaggattc
    12301 gatattagcc ttggtagaag tccagtagtc gtccttgctt gcttggaaga gaacggttgg
    12361 ggcgatttct ttgaatttgt ctacgaattt ttgtgtacgt ggtgaagcga taatcaaatc
    12421 aggctcaagg gcggcgatag cttctaaatc aggttctttc atagaaccaa catttttgac
    12481 agttcccact aggtctttta gataagtcgg aacagttttt gtaggcattc cgacgatatt
    12541 tttttcaaat cctaaagcgc gaatagtatc cgcagcgccg aggtcaaagg tcacaatctt
    12601 ttcaggaact ttggaaagtt tgacctcgtc cagtgaactt ttaatggtta cctctgttgg
    12661 agcagagcta ctggtctctg tctgactagt gcttgagttt gtactacatg caccaagtag
    12721 gagcaagaag ctggccacta gggcagtgaa ataaagttta agggatgttt tcataatttc
    12781 tcctttttaa aatgtgataa cgatttaggg agtctcttga tcttattgat taagagactg
    12841 aaggttctct aacttgagct tttatgttac tagctataga tacagatctt tttgtcattg
    12901 atatcagcta gcgtgatggg aatctcataa agttggctga gcaggtcagc ctgcatgatt
    12961 tgatcggtgc ttcccttgct aaagacctga ccgtccttga aggcgacaat ttcatctgca
    13021 tactgactgg ccatgttgat atcgtggagg acgatgataa tggtcttgcc gagttcctcc
    13081 accagtcgtc gaagaatttg catcatgctg acgctttgct tgatatcgag attgttgagt
    13141 ggttcgtcca gcaagataaa gtccgtatcc tgggccagta ccatagcgat aaagacgcgc
    13201 tggagttgcc cccctgacag gctattgatg tagcggtctt ttaagttggt cagttccaaa
    13261 tagttcagag tttctcggat tttttcccag tcttctgatc taagtcgacc tcggctgtag
    13321 ggaaaacgtc caaaactgac cagttcttca acagtcaatt tggcttggta attgattttc
    13381 tgttttagga tggttagttc ttgggccagt tcttgcgaat tccagctctc gatttcacgt
    13441 cctttgatac tgagaactcc ctgatctttc ttggttagtc tgctcatgat ggagaggaga
    13501 gtcgattttc cagcaccatt tggaccaata aaggctgtca gtttttgagg actgacttca
    13561 agcgaaatgc cttgcaaaat atcctgtttt tgaatggatt tgtcaatgtt ttccagtttc
    13621 actgacgagc cctcctatat agtaagataa agaataagaa gccacccaca ctctcaatga
    13681 tcatactgat acgaatttcc agtgcaaaga ctcgttcaat caaggcttgc cccaaggtta
    13741 agctaataaa tccaaccaga atggccacta taaagagtaa cttgtgctga tagtctttga
    13801 caatcaggta ggtgaggttg gccagcataa agccgaagaa ggccataggt cctaccaagg
    13861 cagtggccgt tgaggtcaaa agcacgattc cccagaggag ctctttctgt tctttttcaa
    13921 catcgagtcc caatatctga gccgtttctc tttgcaggtg caagacatct agaacgactg
    13981 cttttcgaaa gaaaaagatt gtcaaagcga ggatgatcag agaaccgatg gctaggatgg
    14041 aagtgttaag atgttgaaag gaggcaaaaa gactattttg cagtttatcg tattcgtttg
    14101 gatccattag gacttgaagg aaggtgctga tatttcgaaa gagacttctg agcgctagac
    14161 agatcagcag gatgaagacc aggtcttgct tcatcagtgt cttcaagtaa ccttgtaagg
    14221 cgagaaagaa gagggactgg acaagaagta agactaggaa ttctaagata ggggatttgc
    14281 caagttgaag aaacttgctt tcaaaaacca gtagtagggt ttgtagtagg acgtagaagg
    14341 attcaattcc caaaatacta ggcgtcagga agcgattttc cgtcaaggtt tgaaaactaa
    14401 tggtcgaaat cccagtcgcg atggctacca agagataaac gatgatcttt tgggaacgca
    14461 acttccaagc aaaggctgac aagtgagtga tgggccaaaa gtagagaaga caagctccga
    14521 tggcaagaat aatgagaatc cagaagagct tggtatgttt gcttttagtc tgcatctttt
    14581 cgtccccctc tccagagaag taggataaag acgagactac cgatgattcc tagcaagaga
    14641 ctgacagaca actcataggg cctaatcaga actcgggata ggatatcgca agccagaact
    14701 agattggcac caaccagtgc gaccatgagt ttggtttgac ttagattatc tccatagcac
    14761 ttgcgaacaa gattgggaac gataactccg agaaatggta ggccacccac ggtaatcatg
    14821 gtgacgcttg tcgttagcgc caccagaaag agggccagtt tttcaagtag ggagtaggaa
    14881 atccccaaac tctcgctggt ttctttccct agattcatga tggtgaaggt ttgggataat
    14941 ttccaaacgg ttatcaggat gatgaggcct aagaagagcc actcatactg atgggtctga
    15001 atcatggaga aggagccctg ggtccaggca gtcatactct gaaccagatt gaaacgatag
    15061 gcgataactt ctgtgactga gccgataatc ccgctataga tgatcccaat cagaggcaac
    15121 atccaccttt cctttacagt aaaaatggtc ataaaggcta ggaagaagag ggtgaatacg
    15181 atggatgaaa caaaagcgaa gagcatcttt tgggtcagac tagccgatgg aaagacaaaa
    15241 aggctcagca ccattcccag tttggcggct tcagtcgttc caactgtact cggtgcagca
    15301 aactgatttt gggtaatagt ctgcatgaga aggcctgcca tactcatact agaggcagtc
    15361 aggagaatac tgatagttct tgggagacgg gactcttgaa agaggagcca ggtctgctgg
    15421 tcgaaatcaa atagctttcc ccatgaaaaa tcactggtcc caatgctaat agagagaaag
    15481 actaggagta gaagtaagcc aattaaataa tgagaaagtt tcataccccg tcctttcatg
    15541 tagatttggt atcgaaagat atctgcggat ataaatgtaa cattattttt ctaatctgtc
    15601 aataaaattt ctgacaattt aataaataca acaaggagag agcaacaaga ctttctcctt
    15661 tgttatccta ttctaaaatg tttttacctt aatctgataa aataatatct tcgagggagt
    15721 agctagccgt ccaatcaaga tattgtttag cttttgaagc atctgctagg acactggctg
    15781 ggtcactagc acgtcgagca acaatctcgt gtgggatttt ttaatttagt aattcttcag
    15841 cagttttaaa gatttctttg atagtatagc cttttttagt tcctaagtta aagatttgag
    15901 aagaactgtc ttcttgaaat aggtagttca ttcctttaac atgagcctat gcaaggtcca
    15961 agacataaat gtaatctcga atacatgaac cgtcacgtgt atcgtagtca tctccaaata
    16021 tttttaagct atcattttgt cccaatgcgg tcttgttgat atttggaatg atgtgagttg
    16081 gatttttcac acgcagaccg tttgaagcat ccatttcagc cccagcaaca ttaaagtaac
    16141 ggaaaataac atatttccag tcgtagcgat tggccatcca gtaaatcatt cgttcgccca
    16201 tcagttttgt ctctgtataa gggttgacag ggtcgatcag ggtatcttca gtcgccggct
    16261 tgtcaataca gttatttcca tagagagaag cagtcgaaga gaacatgatt ttttgagtgc
    16321 caacttcaga taagactttg agaacttggt tcctaccagc aacgttggca gtgaagtatt
    16381 tacttggatt ttcaatactt tcgctcacaa caatttcacc tgcataatgg aggacagcat
    16441 caatctgatt ttcttttaag taagccttta aggcgctagc atcataaaca tccagttctt
    16501 taaagctagc acgactatcc acagccgctc gatttcctgt ggagagatta tcgaggacat
    16561 gcaccttata gccagcattt aaaagagctt taacggtatg ggagccaatg tagctagtcc
    16621 cacctgtaac aagaattgtt ttggtcatga ttttttcctt ttctagtttt gtactatagt
    16681 aaattgaaat aagatatgaa caactctatt aggaaagtca aattaatttc tagaaatgtt
    16741 ttagcagcta cagcgtacta ttccaaactc aaccaactat atatttaaag aaagaagaaa
    16801 gggaagtcaa ctattttctg taaatttcat gaaaaatcca aacaactttg atggtgtatt
    16861 gttttttgtt tggaaataaa tattcgagtt aattttggaa tgtttactag attttgcact
    16921 acatgcaaga gaatactatc cttttctaag atagagcagg actaagatac taacttagaa
    16981 atccaccttc ccactatcct tctcctataa aaagtggtaa aatggatgaa agaaagaagg
    17041 aactgaaatg acaacattat tttcaaaaat taaagaagta acagaacttg ctgcagtctc
    17101 aggtcatgaa gcgcctgtcc gtgcttatct tcgtgaaaag ttgacaccgc atgtggatga
    17161 agtggtgaca gatggcttgg gtggtatttt tggtatcaaa cattcagaag ctgtggatgc
    17221 accgcgcgtc ttggtcgctt ctcatatgga cgaagttggt tttatggtca gcgaaatcaa
    17281 gccagatggt accttccgtg tcgtagaaat cggtggctgg aaccccatgg tggttagcag
    17341 ccaacgtttc aaactcttga ctcgtgatgg tcatgaaatt cctgtgattt caggttctgt
    17401 tcctccgcat ttgactcgtg gaaagggggg accaaccatg ccagccattg ccgatatcgt
    17461 ttttgatggt ggttttgcgg acaaggctga ggcagaaagt tttggcatcc gtcctggtga
    17521 taccatcgta ccagatagtt ctgcaatttt gacagccaat gaaaaaaata tcatctcaaa
    17581 agcttgggat aaccgctacg gtgtcctcat ggtaagcgag ctagctgaag ctttatcagg
    17641 tcaaaaactc ggcaatgaac tctatctggg ttctaacgtc caagaagaag ttggtctgcg
    17701 tggcgctcat acctctacaa ccaagtttga cccagaagtc ttcctagcag ttgattgctc
    17761 cccagcaggt gatgtctacg gtggtcaagg caagattgga gatggaacct tgattcgttt
    17821 ctatgatcca ggtcacttgc ttctcccagg gatgaaggat ttccttttga caacggctga
    17881 agaagctggt atcaagtacc aatactactg tggtaaaggc ggaacagatg caggtgcagc
    17941 tcatctgaaa aatggtggtg tcccatcaac aactatcggt gtctgcgctc gttatatcca
    18001 ttctcaccaa accctctatg caatggatga cttcctagaa gcgcaagctt tcttacaagc
    18061 cttggtgaag aaattggatc gttcaacggt tgatttgatt aaacattatt aaaccataag
    18121 ggaggtggta gggatggcag aaccaaacct agaaagcctt ataaaagatc tttacaatca
    18181 tgctcgacat gatttgagtg aagatttagt tgctgctctc ctagagacta ctaaaaaact
    18241 gcctactaca aatgagcaat tgcaggcagt tcgtctctca ggcctggtca atcgtgaatt
    18301 gctcctaaat cccaaacatc cagcacctga gttgctcaac ttggctcgct ttatcaaaag
    18361 agaagaagcc aagtacagag gaactgcgac ttctgcactt atgtatgagg aactttttaa
    18421 aatgctttga ttccattgtg gatcaaagca ttttttataa gacctatctc gtgagcgttc
    18481 aaatagtagt aacaaggaat catgagaagt cagccgagac catagtagtg aagaaacttc
    18541 tgtaatggaa gtggagtgaa gtgaggaatc gtcaaacggt aggggatagg ctgtttgaag
    18601 ggtgctacga aaaagatagg gtaaggtgaa attatagcgg aatgaaataa gatatgaaca
    18661 aattgattag ggaaatcaaa tgaatttata gaaatctttt agcagtcatg gtgtcctatt
    18721 ccagtttcga aatgctataa agacgaacaa attgattggg aaattcaaat cgctttctat
    18781 caatgtttta gaagatacag tgccctagtc caacttcaat atactataaa agaacagatg
    18841 gaagcaatta tgatttactt ctatctttaa aataaatgat ctgataggaa aaatgtgtcc
    18901 cctcataaaa aataggatag tacggatgga aggcttttgt agactggagg acgaaggaat
    18961 ttagaaactc tcgttaaaag ttagttgagc cggagtatgg tggtgtgaat aattatcaaa
    19021 aattatttcc aaatcgaaat agttgacagt tagaacgatg agtgttacaa ttattttatt
    19081 catttcgaca tcgaaataaa ttggaggtgt tatgaaagat agtcatttgc tagcccatca
    19141 tattcgtttg ttgaatgggc ggatttttca aaagttactg agtcaagatc ctgaggctct
    19201 ttataggggt gaacagggca agattttagc ggttttatgg aatagtgaaa ctggctgcgc
    19261 aactgcgaca gatatcgcgc ttgcgactgg gcttgcgaat aatacgctga cgactatgat
    19321 aaaaaagcta gaggaacaaa agcttgtaat tgttagtccg tgtggaaaag acaagcgtaa
    19381 gaagtattta gttttaacgg agttaggcaa gtcccagaaa gaagtggggc atcgtgtcag
    19441 tcagaaattg gatactatct tttacaaagg attttcagag gaagaaattc accaatttga
    19501 aggttttcaa gaaagaattt tggcgaattt gaaagagaag ggaaatgagg tttagaatat
    19561 gtcacaacaa gtgaaaaatg ctcacaacct atacatccat gccattcaag acggacgagt
    19621 tgctgaggct caagcccagt ctgtagggga tacctatatc caacattcga caggtgttcc
    19681 tgacgggaaa gaaggatttg cagccttctt tgcagatttc tttgagcgtc atccagagcg
    19741 tcagattaag attgtccgca ccattgagga tggcaatctg gtctttgttc atgttcatca
    19801 atatctgaat ggtggagaag ctcaatgggt gacgacggat actttccgtg cggatgagaa
    19861 tggtcgtatt gttgagcatt gggatgtcat tgactactat cgaacacctg aaaatgatca
    19921 actagatcaa atttttggag attttgaaat caaggatttg gataagaaag cagaaaataa
    19981 aaagctggtt cgccgtttct tgacagaaat tttccaaaat ggggagctag agcagtggag
    20041 tgattatgtg gcagacgatt tgattcagca taatcatgag attggacaag gaagtgctgc
    20101 ttataaaaac tatgtggctg aatatagtgt cacttttgac tttgttttcc aactcttagg
    20161 acaaggaaac tatgtggtta gctatggtca gactcagatt gatggcgttg cttatgccca
    20221 gtacgatatc ttccgtttag agaacgggaa aattgtggag cattgggata ataaggaagt
    20281 catgcctaag gtagaagact tgactaatcg agggaagttt taaattgagg acaaagaatg
    20341 attgaataca aaaatgtagc actgcgctac acagaaaagg atgtcttgag agatgtcaac
    20401 ttacagattg aggatgggga atttatggtt ttagtagggc cttctgggtc aggtaagacg
    20461 accatgctca agatgattaa ccgtcttttg gaaccaactg atggaaatat ttatatggat
    20521 gggaagcgca tcaaagacta tgatgagcgt gaacttcgtc tttctactgg ttatgtttta
    20581 caggctattg ctctttttcc aaatctaaca gttgcggaaa atattgctct cattcctgaa
    20641 atgaaggggt ggagcaagga agaaattacg aagaaaacag aagagctttt ggctaaggtt
    20701 ggtttaccag tagccgagta tgggcatcgc ttacctagtg aattatctgg tggagaacag
    20761 caacgggtcg gtattgtccg agctatgatt ggtcagccca agattttcct catggatgaa
    20821 cccttttcgg ccttggatgc tatttcgaga aaacagttgc aggttctgac aaaagaattg
    20881 cataaagagt ttgggatgac aacgattttt gtaacccatg atacggatga agccttgaag
    20941 ttggcggacc gtattgctgt cttgcaggat ggagaaattc gccaggtagc gaatcccgag
    21001 acaattttaa aagtgcctgc aacagacttt gtagcagact tgtttggagg tagtgttcat
    21061 gactaattta attgcaactt ttcaggatcg ttttagtgat tggttgacag ctctatctca
    21121 acatttgcag ttgtcacttt tgaccttgtt actagctatt ttgcttgcga ttcccttggc
    21181 tgtttttctt cgctatcatg agaagctggc cgactgggtc ttgcagattg caggtatttt
    21241 ccagaccatc ccgtctctgg ccttgttggg gctctttatc cctttgatgg gaattgggac
    21301 cttgccggct ttgacagctc tagtgattta tgcgattttt ccgattttac aaaatactat
    21361 tactgggctg aagggaattg atccgagtct tcaagaggct gggattgcct ttgggatgac
    21421 cagatgggag cgtctcaaga agtttgaaat tccacttgcc atgcctgtta tcatgtctgg
    21481 aattcggacg gcagcggtct tgattatcgg tacggctacc ttggcgacct tgattggggc
    21541 agggggactg ggttccttta tcctgttggg aattgaccgt aataatgcca gtttgatttt
    21601 gattggggcc ctttcttctg cagtgctagc tattgccttt aacttcctac taaaagtaat
    21661 ggaaaaagcg aaattgcgga cgattttctc tggttttgcc ttgatggctt tattactggg
    21721 tctgtcttat agtccagccc ttttggctca aaaagagaag gaaaacttga ttattgctgg
    21781 gaaaataggc ccagaaccag aaattttggc taatatgtat aaattgctga ttgaagaaaa
    21841 taccagcatg actgcgactg ttaaaccgaa ttttgggacg acaagtttcc tttatgaagc
    21901 tctgaaaaaa ggtgatattg acatttatcc tgaatttacc ggtacggtga ctgaaagttt
    21961 gcttcaacca tcacccaagg tgagtcatga gccagagcag gtttatcaag tggcgcgtga
    22021 tggaattgcc aagcaggatc atctagccta tctcaaacct atgtcttatc aaaataccta
    22081 tgctgtagct gttccgaaaa agattgctca agaatatggc ttgaagacca tttcggattt
    22141 gaaaaaagtg gaagggcagc tgaaggcagg ctttacgctt gagtttaacg accgtgaaga
    22201 tggaaataag ggcttgcaat caatgtatgg tctcaatctc aatgtggcga ctatgcagcc
    22261 agctcttcgc tatcaggcaa ttcagtcagg ggatattcaa atcacggatg cctattcgac
    22321 tgatgcggaa ttggagcgtt atgatttaca ggtcttggaa gatgacaagc aactcttccc
    22381 accttatcaa ggggctccac tcatgaaaga agctcttctc aagaaacacc cagagttgga
    22441 aagagttctt aatacattgg ctggtaagat tacagaaagc cagatgagcc agctcaacta
    22501 ccaagtcggt gttgaaggca agtcagcaaa gcaagtagcc aaggagtttc tccaagaaca
    22561 aggtttgttg aagaaatgat gggacagaga ctttaaacat actgaactca acttccttaa
    22621 acgactagat aaaagaatgc tcagacaatt tcgtctgggc ttttttgatg tgagaatgac
    22681 tgaatgtcac ttaaaatgga aagaaagaga aaattttcat gattttctaa aattttactg
    22741 taaagacagt tgactattca taaaataggt gtataatatt ttgtgaacta cttaacaaat
    22801 aagaggtttc agctcatgtc gactaaggtt agaaatcttg tgtataggca gttcattatc
    22861 taatagagcg ttgcgtccga aagtctatcc agacacggct ctttaaaaac aaaaggagaa
    22921 atgatgcata cttatttgca aaagaaaatt gaaaatatca aaacaaccct aggtgaaatg
    22981 tcaggtggtt accgtcgtat ggttgcggct atggctgatt taggattttc aggaactatg
    23041 aaggctatct gggatgacct ctttgcccat cgtagttttg cccagtggat ttatttgctg
    23101 gttttaggaa gttttcctct ctggctggag ttggtttacg aacatcgtat tgttgactgg
    23161 attgggatga tttgtagctt gacagggatt atctgtgtaa tctttgtatc ggaaggtcga
    23221 gcaagtaatt atctttttgg cttgattaac tctgttattt accttatttt ggccctacag
    23281 aaaggctttt atggtgaggt gctgacgaca ctttacttca cagtcatgca gccaattgga
    23341 cttctagttt ggatttatca ggcacagttt aagaaggaaa agcaggagtt tgtcgcgcgt
    23401 aaactggacg gcaagggctg gacaaagtat ctttccatta gtgtgctttg gtggttggcc
    23461 tttggcttca tttatcagtc tattggtgcc aatcgtccct atcgtgattc aatcacagat
    23521 gcaaccaatg gggtagggca aatcctcatg acagctgttt accgtgaaca gtggatattc
    23581 tgggcggcta ccaatgtttt ttcaatctat ctctggtggg gagaaagcct gcaaattcaa
    23641 gggaaatatc taatttatct cattaacagt ctagttggtt ggtatcaatg gagcaaggca
    23701 gctaagcaga atactgattt acttaactag gaaaagatgt ttgaaagtgc tgttttgaga
    23761 ttttgattaa aacagatata gttgataatc aaggatttat agtatgaaaa agaggatcgg
    23821 cgggtcctct tttgttgttg aaaagataaa aaactcagta acctagaaat aagacaactg
    23881 aagctttact ctatattcaa tttttaggaa tgagaaggtc tagataaaat tggacaactt
    23941 cctggtctgt gaaatcttga ccttttttga gccaccaggt caatgtctcg ataaagttgg
    24001 acacgaccaa gtgttggagg taagaagtag gcatattagg gtgggcttct tttaaattat
    24061 cagctagcac ggaatagaca tggtgttcta gctctttatg gagttgacgg aggaagtagt
    24121 catttttgga aaatagcaga ctggtgatat ggtcttggtt tttatgaaaa tggagaaaga
    24181 ggtgggcgag gtagtcctcg gttgaaatgg cttgctctct ttcaaaaaga tgatggaaga
    24241 ggtagcggca gagctggtcc agaagaagct ccttactctc atagtgacag taaaaggtgg
    24301 atcttcccac atctgcgaga ttaatgatat cctgaacagt agtggcctcg tagcccttag
    24361 cattcaaaag ttgtataaaa gcttgataga tggctttttt ggttttgctg atacggcggt
    24421 caatgttagt catatggaca cttaaggcaa attgttcaga actgaataaa gctgacgttt
    24481 tgcttctatc ctttctttga gttttagtgg ataatgataa tgaacaaggt gttcataaac
    24541 ctattataac aaaggaatga gaaatatgaa ggcaaaatat gctgtttggg tggctttttt
    24601 cttaaatttg acttatgcca ttgttgagtt tattgcaggt ggagtatttg gttctagcgc
    24661 tgttcttgct gactctgtgc atgacttggg agatgtgatt gcaattggaa tatcagcttt
    24721 tctagaaaca atctccaatc gtgaagaaga caatcagtac accttgggct ataagcggtt
    24781 tagcctgcta ggagccttgg taacagctgt gattctcgta acaggctctg ttctagtcat
    24841 tttggaaaat gtcacgaaga ttttgcatcc gcaaccagtc aatgatgagg ggattctctg
    24901 gttaggaatt attgcgatta ctatcaatct gttagcgagt ctggtggttg gtaagggaaa
    24961 gacaaagaat gagtctattc tgagtctgca ttttctggaa gatacgctag ggtgggtagc
    25021 tgttatcctg atggcgattg ttcttcgatt tacggactgg tatatcctag atcctctttt
    25081 gtcccttgtc atttctttct ttattctttc aaaagccctt ccacgttttt ggtctacact
    25141 caagattttc ttggatgctg tgccagaagg tcttgatatc aagcaagtaa agagtggcct
    25201 ggagcgattg gacaatgtgg tcagccttaa tcagcttaat ctctggacta tggatgcttt
    25261 ggaaaaaaat gccattgtcc atgtttgtct aaaagaaatg gaacatatgg aaacttgtaa
    25321 agagtctatt cgaattttcc taaaagattg tggttttcaa aatattacca ttgaaattga
    25381 tgctgaccta gaaactcacc aaacccataa gcgaaaggtg tgtgacttgg aacggagtta
    25441 tgagcaccaa cattagaaaa aagtgaaaaa tacttgggta ctatcttatt tggaatagag
    25501 taatttcttt attatttaaa tatttcaaaa attggtaaga gaagagcatt gtataaactc
    25561 catatatatg attgttaatg ataaaaattt ttcgattaga tacaaaatgc ttgacttgga
    25621 gtcaactcaa agttatataa taagataagt gagttagaat agcgtgaatt cagtgaatga
    25681 aatgagagga ggttagcgtg tgaatattaa atctgccagt gatttgttgg gaatttcagc
    25741 ggatacgatt cggtattatg aacgggttgg tcttgtgcca ccgattactc gtactgctac
    25801 tgggattcgt gattttcaag atcaggatat cgaagcgctg gaatttatta agtgttttcg
    25861 ttcggcgggt gtctctgtag atagtttagt tgactatatg tcgctctacc aaaagggaga
    25921 tgaaacgaga gaggagaggc ttggtatttt agaagaggaa aagcaaaaat tagaggagcg
    25981 cttgtctcag ctacagacag ctttaaatcg tttaaatctc aaaattaaac tttataagga
    26041 aggaaaattt taaatgaaat cagcagtata tacaaaggca ggtcaggttg gacttgctag
    26101 cattgaacgt ccgcaaataa tagaagcgga tgatgtgatt attcgtgtgg ttcgtgcgtg
    26161 cgtttgtggt tcagatttat ggaggtaccg taatccagaa acgaaagctg gacacaaaaa
    26221 tagtggacac gaagcgattg ggattgttga agaagctggg gaagccgtta cgacggtgaa
    26281 accaggtgat tttgtgattg tcccttttac acatggatgt ggtgagtgtg atgcctgtct
    26341 tgctggattt gacggttctt gcgacaatca tattggcaat aatttggggg gtgattttca
    26401 ggcagaatat attcgcttcc actatgcaaa ctgggcgctg gttaaaatcc ctggtcaacc
    26461 ttctgactat acagaaggga tgctccagtc ccttttgact cttgcagatg tcatgccgac
    26521 aggctatcat gcggcgcgtg ttgcaaatgt tcaaaaaggg gacaaggttg ttgttatcgg
    26581 tgatggggct gttggtcaat gtgctgtcat cgcggctaag atgcgtggag catcacaaat
    26641 tatccttatg agccgtcatg aagaccgtca aaagatggct atggagtcag gtgcgacagc
    26701 tgttgttgca gaacgtggtc aagaaggaat taccaaggtg cgtgaaatcc tcggtggagg
    26761 agcagacgca gcacttgaat gtgttggtac ggaggctgct atagaacagg cgctaggtgt
    26821 tcttcataat ggagggcgta tgggctttgt aggagtccca cactataata atcgtgctct
    26881 tggttcgaca tttatgcaaa atatctctgt agcaggtggg gcagcttctg ctacaacata
    26941 cgataagcaa tttttactaa aagccgtcct tgatggtgat atcaatccag gtcgcgtctt
    27001 tacttcaagt tataaactgg aagatatcga ccaggcctat aaagatatgg atgaacgtaa
    27061 gaccattaag tctatgattg taatcgaata aaaaacgaat aggagtttta gaactctatt
    27121 cgttttttat gttatcctat tcttgattta gggtactttc tcttaatgtc agtctggttc
    27181 ccagcatggt caggctaggg attttccgac cgtggaggac ttccttgtta agaatatcca
    27241 tacctgctcg ccccatttct tcagtataga ctgtgatgct ggagagggga ggataaacct
    27301 gcttggtcag actggtgtcg ttgaatgaaa tgaggctgac gcgatctggc aggctgattc
    27361 cagcttcttg gagggcacgg agggcaccga tagctaaact atcgctggct gcgaaaaatg
    27421 ctggcggaag ttggtctccc aagctctgaa tggcctcctt cattaagtca tagccagact
    27481 gggcagtaaa tcttccttga aagaccagtt catcatgata gattcccctc gcttgactgt
    27541 agtttttgaa gttttctaga cgcttgtcct gaatgatttc ttcttggtct gttgtttcct
    27601 caagccctgt tagaatcccg atgcggtcca tcccttgact gaggaaataa tcgacaacct
    27661 gtttcatagc agtgtaaaaa tccgtgataa tacaggtatg tcccagggaa agtgtatcgc
    27721 tgtctagaaa tacaagaggc ttttggtatt cttcaaaggc agaaatctga gctcggctaa
    27781 attttccgat gcagagaatc ccaatcactt cctcgcttaa ggtaaaagga tggtcattaa
    27841 aatagcgcaa gatatcgtag tccaactctt gggctctttt ttctattcct aggcgaatct
    27901 ggtagtagta gaggtcgtct agctcccctt gttcgctgac ccattggata atggcaatct
    27961 tttgcttggg cttgtgggac tcgcctgtct tgaggtgttt ggtgtagcct aactcttcag
    28021 caacggttaa aatacggtgt ctggtttctt ctgtaacaga taggctctgg tcgcggttga
    28081 ggacacggga tacggtcgcg attgagacag aggctagctg tgcaatgtct tttaaggtag
    28141 ccataaatcc tccttgatta ggttagtata tcatattttt cttcttttta ctgatatttt
    28201 agtaaaattt tagtaaaaag gattgacctt gggaaatttc ttggatacaa tagaaagaaa
    28261 acgattacac gttaagatgg cttaacggac agtcaaagga gaattcatat ggcacaacat
    28321 cttactactg aagtccttcg caaagacttt cttgctgttt ttggtcaaga agcagaccaa
    28381 accttctttt caccaggccg tattaatttg attggtgaac acacagacta caacggtggg
    28441 cacgtttttc ctgctgctat ttccttggga acttacggtg cagctcgtaa gcgtgacgac
    28501 caagtcttgc gtttctactc agctaacttt gaggacaagg gcattatcga agtgcctctc
    28561 gctgacctca agtttgaaaa agagcacaac tggaccaatt atccaaaagg tgtccttcat
    28621 ttcttgcaag aagctgggca cgtgattgac aaaggttttg atttttatgt ttatgggaat
    28681 atcccaaatg gtgctggctt gtcttcttca gcatccttgg agctcttgac aggagtcgtg
    28741 gcagagcatc tctttgattt aaaattagag cgtctcgatt tggttaaaat cggaaaacaa
    28801 acagaaaaca actttatcgg agtcaactct ggtatcatgg accagtttgc tattggtatg
    28861 ggggccgatc aacgtgctat ttaccttgat accaacacct tagagtatga tttggtgcca
    28921 cttgatttga aggacaatgt cgttgttatc atgaacacca acaaacgccg tgaattggcg
    28981 gactctaaat acaatgaacg tcgtgctgag tgtgaaaaag cagtggaaga attgcaagtt
    29041 gccttggata ttcagaccct gggtgaattg gacgagtggg ccgttgacca atatagctat
    29101 ttgattaaag atgaaaatcg tttgaaacgt gctcgccatg ctgtgcttga aaaccaacgt
    29161 acccttaaag ctcaagcagc ccttcaagca ggtgatttgg aaacatttgg tcgtttgatg
    29221 aatgcgtcac acgtttctct ggagcatgat tatgaagtaa ctggtttgga attggatact
    29281 cttgttcaca cagcttgggc acaagaagga gttctcggtg ctcgtatgac aggggctggt
    29341 tttggtggct gtgccattgc cttggttcaa aaagatactg ttgaggcctt taaggaagct
    29401 gtaggcaaac actacgagga agtagttgga tacgctccaa gcttctatat cgctgaagtt
    29461 gcaggtggca ctcgcgtcct tgactagtca aaaggaggct ctatagtgat cttagtagat
    29521 aaatttgtaa cacatgtcat ttctgaaagt tcatttgagg aaatggatcg aatctacctg
    29581 accaatcgtg ttttggcacg agtgggagaa ggtgttttgg aagttgagac caatctggat
    29641 aaattgattg acctcaagga ccagctagtt gaggaagccg ttcgattaga gacgattgag
    29701 gatagtcaga ctgcgcgtga aatccttggt actgaattga tggacttggt gactccttgt
    29761 ccgagtcagg tcaatcgtga cttctgggaa gcctatgcct actctcctga gcaagcgata
    29821 gaggattttt atcaactcag tcagaaaaat gactacatca aactcaaggc cattgctaaa
    29881 aatatcgctt atcgtgttcc atctgattat ggagaacttg aaattaccat caatctctct
    29941 aagcctgaaa aggatccgaa agagattgcg gcagccaagt tggtgcaagc tagtaattat
    30001 cctcagtgtc aactttgttt agagaatgag ggttaccatg gtcgggtcaa ccacccagct
    30061 cgcaccaacc accggattat ccgttttgaa atggttggtc aggaatgggg tttccagtat
    30121 tcgccctatg cttactttaa tgagcattgt atctttttag atggccagca tcgtcccatg
    30181 gccattagtc gtcagagttt tgaacgtctg ttggctatcg tagagcagtt tccaggatat
    30241 tttgctggat ctaatgccga cctgccgatt gtggggggct ctattctaac tcatgatcat
    30301 tatcagggag gccgtcacgt atttcctatg gaattggctc ccttgcaaaa gaccttccga
    30361 tttgctggtt ttgagcaggt caaggctgga attatcaagt ggccaatgtc tgtcctacgc
    30421 ttgacttcgg attccaaaga ggatttgatt aacttagctg ataagatttt ccaggaatgg
    30481 cgtcagtatt cagattctag tgtgcagatt ttagcagaga cagacgggac accgcatcac
    30541 accatcacac caatagcgcg taagcgtgat ggacagtttg agttggactt ggtcttgcga
    30601 gacaatcaga cttcagcaga gcatcctgat ggcatctatc atccccacaa ggatgtccaa
    30661 catatcaaga aggaaaatat cggcttgatt gaggtcatgg gcttggcaat cttgccacca
    30721 cgtctgaaag aagaagtgga gcaagtcgct agctatcttg taggagaagc tgttacagtt
    30781 gccgattatc atcaggagtg ggcagaccaa ctcaaatccc aacatccaga cctaacggat
    30841 aaagaaaaag cccttgcaat cgtcaaggac tctgtggggg ctatctttgt gcgtgtactt
    30901 gaggatgcag gagtctacaa gcagacagag cagggacagg cggcctttat gcgctttgtg
    30961 gaacaggtcg gaatttcact agactaggag ctttctcctt gcacagtcct ataaaaagta
    31021 gtatcatagt gtcgtttgaa atatcaggag gaaacgatga aagactttca ttttgacgct
    31081 atatctgcct ttgaaaatta cgaaattgaa aaaatgagag atggtcacgt tgtggtgacg
    31141 accaaagtag tgaactcgtc gctcaactac tatggcaatg cccatggtgg ctatctattc
    31201 acgctatgtg accaaatcag tggtttggtg gttatctcgc tgggacttga tggggtgaca
    31261 ctccaatcct ctatcaacta ccttaaggca ggaaaactcg acgatgtatt gaccattaaa
    31321 ggagaatgtg tccatcaagg tcgtacaacc tgtgtaatgg atgtggatat caccaatcaa
    31381 gaaggcagaa atgtctgcaa agcaaccttt accatgtttg tcacaggccg gcggtcagaa
    31441 gacagacagg taaggatata aagagtaatt taatagagtg aggtgaattt tggaatttat
    31501 aagatttgcc ttactcattt tttgatattg atatgattta attctaaaat aga
//
LOCUS       DAVLDI010000023        29136 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLDI010000023 DAVLDI010000000
VERSION     DAVLDI010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.023"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            170..2062
                     /gene="pepO"
                     /locus_tag="VXD01_001053"
     CDS             170..2062
                     /gene="pepO"
                     /locus_tag="VXD01_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV0601475.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(2185..2814)
                     /locus_tag="VXD01_001054"
     CDS             complement(2185..2814)
                     /locus_tag="VXD01_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV0601476.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            3830..6052
                     /locus_tag="VXD01_001055"
     CDS             3830..6052
                     /locus_tag="VXD01_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV0601477.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFSIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            6082..6525
                     /locus_tag="VXD01_001056"
     CDS             6082..6525
                     /locus_tag="VXD01_001056"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV0601478.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(6792..6978)
                     /locus_tag="VXD01_001057"
                     /pseudo
     CDS             complement(6792..6978)
                     /locus_tag="VXD01_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7142..7792)
                     /locus_tag="VXD01_001058"
     CDS             complement(7142..7792)
                     /locus_tag="VXD01_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV0601479.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            7904..8746
                     /locus_tag="VXD01_001059"
     CDS             7904..8746
                     /locus_tag="VXD01_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV0601480.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            8822..9259
                     /locus_tag="VXD01_001060"
     CDS             8822..9259
                     /locus_tag="VXD01_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV0601481.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            9328..9630
                     /locus_tag="VXD01_001061"
     CDS             9328..9630
                     /locus_tag="VXD01_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601482.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(9721..10794)
                     /locus_tag="VXD01_001062"
     CDS             complement(9721..10794)
                     /locus_tag="VXD01_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV0601483.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            10950..11627
                     /locus_tag="VXD01_001063"
     CDS             10950..11627
                     /locus_tag="VXD01_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0601484.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            11620..12594
                     /locus_tag="VXD01_001064"
     CDS             11620..12594
                     /locus_tag="VXD01_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0601485.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(12643..14586)
                     /gene="thrS"
                     /locus_tag="VXD01_001065"
     CDS             complement(12643..14586)
                     /gene="thrS"
                     /locus_tag="VXD01_001065"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV0601486.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(14644..14967)
                     /locus_tag="VXD01_001066"
     CDS             complement(14644..14967)
                     /locus_tag="VXD01_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV0601487.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            15826..16454
                     /locus_tag="VXD01_001067"
                     /pseudo
     CDS             15826..16454
                     /locus_tag="VXD01_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
     gene            16595..16864
                     /gene="rpsO"
                     /locus_tag="VXD01_001068"
     CDS             16595..16864
                     /gene="rpsO"
                     /locus_tag="VXD01_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV0601488.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            17679..18293
                     /locus_tag="VXD01_001069"
     CDS             17679..18293
                     /locus_tag="VXD01_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV0601489.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAILGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(18586..19335)
                     /locus_tag="VXD01_001070"
     CDS             complement(18586..19335)
                     /locus_tag="VXD01_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV0601490.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            19468..21804
                     /locus_tag="VXD01_001071"
     CDS             19468..21804
                     /locus_tag="VXD01_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV0601491.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            22333..23796
                     /locus_tag="VXD01_001072"
     CDS             22333..23796
                     /locus_tag="VXD01_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0601492.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKV
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            23789..24217
                     /locus_tag="VXD01_001073"
     CDS             23789..24217
                     /locus_tag="VXD01_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0601493.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            24195..24644
                     /locus_tag="VXD01_001074"
     CDS             24195..24644
                     /locus_tag="VXD01_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0601494.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            24672..24983
                     /locus_tag="VXD01_001075"
     CDS             24672..24983
                     /locus_tag="VXD01_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEV0601495.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            25009..26094
                     /locus_tag="VXD01_001076"
     CDS             25009..26094
                     /locus_tag="VXD01_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEV0601496.1"
                     /translation="MLKHLNLKGHLLTAISYVIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            26105..26800
                     /locus_tag="VXD01_001077"
     CDS             26105..26800
                     /locus_tag="VXD01_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV0601497.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLKSTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            26837..28807
                     /gene="tkt"
                     /locus_tag="VXD01_001078"
     CDS             26837..28807
                     /gene="tkt"
                     /locus_tag="VXD01_001078"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0601498.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMPLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
BASE COUNT         8462 a         5333 c         6612 g         8729 t
ORIGIN      
        1 tctaaattat aaaacgcata gtatcaagtg taaaaaactt ggaattatgc gttttatcat
       61 ggaaagattt tttataatag ctaaaaaata atagttaaat ggttattaat tgcattccct
      121 agtgattttt gttaagataa atgcaaatac aaatgaaagc gagaacaaga tgacacgtta
      181 tcaagatgat ttttatgatg ctatcaatgg agaatggcaa cagacagctg aaatcccagc
      241 agataagtct caaactggag gttttgttga tttagaccag gaaattgaag acctgatgct
      301 ggcgacaaca gacaagtggt tagcaggtga agaagtgcct gaggatgcta tcttggaaaa
      361 ctttgtcaaa taccaccgcc tagttcgtga ttttgacaag agagaagctg acggtatcac
      421 acctgtctta ccactcctta aagaattcca agaattggaa acttttgcgg attttacagc
      481 taaactagca gagtttgagc ttgcaggaaa accaaacttc cttccttttg gtgtatcgcc
      541 agactttatg gatgctagaa tcaatgttct atgggctagc gctccaagca caatcttgcc
      601 agatacgacc tactatgcag aagaacatcc tcagcgcgaa gagctcttga ctctttggaa
      661 agaaagcagc gcaaatctcc tcaaggctta tgatttctct gatgaagaaa ttgaagactt
      721 gctagaaaaa agacttgaat tggaccgccg agttgcggca gtggtgctct ctaatgaaga
      781 aagttcagaa tatgctaaac tctatcatcc atattcttac gaagatttta agaaattcgc
      841 gcctgcccta cctttggatg acttcttcaa agcagttatt gggcaattac cagacaaggt
      901 tattgtagac gaggaacgtt tctggcaagc agcagagcaa ttctacagtg aggaagcctg
      961 gtctctcctt aaagcaacct tgattttgag tgttgtcaat ctttcaacca gctatttaac
     1021 agaggatatc cgtgttttgt ctggtgccta cagccgtgcc ctttctggag ttccagaggc
     1081 aaaagataag gtcaaagcag cttatcatct agcacaagaa cctttcaagc aagccctggg
     1141 tctttggtac gcccgtgaga agttctctcc agaagccaag gcggatgtgg agaaaaaagt
     1201 ggcaaccatg attgatgtct ataaggagcg tctgcttaag aatgactggc tcactccaga
     1261 aacctgtaaa caggctatcg tgaagctcaa tgtgatcaaa ccttatattg gctatccaga
     1321 agaattgcct gcacgttaca aggataaggt agtgaatgaa actgccagtc tttttgagaa
     1381 tgctctagcc tttgcgcgtg tggaaatcaa gcacagttgg agtaagtgga accagcctgt
     1441 agactataag gaatggggca tgcctgctca tatggtcaat gcctactaca atcctcagaa
     1501 gaacctgatt gtctttccag cggccatttt acaggcgcct ttctatgact tgcatcagtc
     1561 atcttctgct aactacggtg gtattggggc agtgattgcc catgaaattt cccacgcctt
     1621 tgatactaac ggggcttcct ttgacgaaaa tggtagcctc aaggattggt ggacagagag
     1681 cgactatgct gccttcaagg agaaaacaca aaaagtcatt gaccaatttg atggacagga
     1741 ttcttatgga gcaaccatta acggtaaatt gactgtatca gaaaacgtgg ctgacttggg
     1801 aggaatcgca gcagcgcttg aagcagctaa gagagaagca gacttctcag cagaagagtt
     1861 cttctacaac ttcggtcgca tctggcgcat gaaaggtcga ccagaattta tgaaactttt
     1921 ggctagcgtc gatgtgcacg caccagccaa actccgtgtc aatgtgcaag taccaaactt
     1981 cgacgatttc tttacaacct atgatgtcaa agaaggagac ggaatgtggc gttcaccaga
     2041 ggagcgcgtg attatttggt aatacaaaaa atctagtcat cagaaaaaag gcatccaatc
     2101 acgtgtgaaa accttgatag gatgcctttt gtaatagaaa gatttgctgg atagtttact
     2161 taaatttcga ttgtcatcat cttgctagaa aaagggattg aaggcctttt cgtgagcgat
     2221 agtagtagct ggaccatgtc ctggatagac atcgtagttt ggtagggtga agagttgggt
     2281 ctggatacta tgaaggagtt gctccatgct accagtcgga aggtcggtcc gtccgatagt
     2341 ttcgcggaat agagcatctc ccgtcaagac taggtgagca tcaggaaaga ctagggaaac
     2401 accaccgata gagtgccctg gggtcggtag aaccttaaaa cgaaattcct ctagttggta
     2461 ttcttcgtga aagacaaagg tgtgttctgc aggttttgtg accacatctg ccatatcatc
     2521 gtggcgaggg agaccggaga gattatcgac aggagtgtag agccagctgg cttcgctctc
     2581 tgcgatatag acaggaggat tgccaaacgt ctcgcgaacc aagtccagac tcatgatatg
     2641 gtcataatgg gcgtgggtca agagaatagc acagatcggt ttgttgatct tctcgattgt
     2701 ctgacgaatg gcttcccaat gactaccagg atcgacgacg atgaggtgct tttcgccttc
     2761 tagataatag gtattttcat aggcaacagg attcacggtt ttatggattt tcatactagc
     2821 tccaatctca aagaatgtac taatactctt cgaaaatctc ttcaaaccgc gtcaacttta
     2881 tctgcaacct caaagcagtg ctttgaacag cctgcggcta gctttctagt ttgctctttg
     2941 attttcattg agtataaatt aagtatagca cagttaggga gaataggtaa ggatttaaaa
     3001 tgaacttaaa aaccagcatg actagatgaa gacaggctgg ttatcaattt atcaatattg
     3061 gaaaggtgtc aattgccctt cataggttgc ataaactccg tcattagctt gtttgataga
     3121 cgtgatgttt agagtgctac cgtagttggc ttatcatttg tcgctatatt cactataagt
     3181 tatcctactg ggcaggttct ggtcgttagc atagtattga acgagttttt tatagctttg
     3241 ctggctgaat aggaacaggc agcaaactcc taacattagg agagcaaaga tagaaatagc
     3301 agtttttttc ataggtattc tccttataaa ctaaaggata gaagaaagta tcttgaggat
     3361 ttttatactc ttcaaaaatc tcttcaaacc gcgtcaacaa tctcttcaaa ccgcgtcaac
     3421 gtcgccttgc cgtatatatg tgactgactt tgtcagtctt atctacaacc tcaaagcagt
     3481 gctttgagca acctgcggct agtttcctag tttgctcttt gattttcatt gagtattaat
     3541 tccaaaatcc agtcaaggta ccagtgtatg tgatacgagt tccaccgttt atctttcgta
     3601 tcttcaatgg aattggggaa atcagaaagt ctttgggtta caatatggtt tccgttcttc
     3661 tatctctcct tctatcacct aagtttaaaa tctaacttcg tagtatatta tgggccaata
     3721 attcagaatt atcaagcaat tttgaattat ttttttctta ttctgttcca atctagtttt
     3781 catattctta aaaaagtgat aaaatggtag gaagaattgg agagtagaga tgccgaaaga
     3841 agtgaattta acaggcgaag aagttgtcgc tttaaccaaa gaatatttaa cggaagagga
     3901 tgttcatttt gtccataagg ccttggtcta tgctgttgaa tgccacagtg gtcaatatcg
     3961 caaatcaggc gagccttata tcattcaccc tatccaagtg gcaggtattt tagctaagct
     4021 aaagctggat gctgtaacag tagcttgtgg attcttgcat gatgtggtgg aagatacaga
     4081 tgcgaccttg gacgatttgg aaagagagtt tggtcctgat gtgcgggtga ttgttgacgg
     4141 agttaccaag cttggcaagg tcgagtacaa atcgatcgag gagcaattag cggaaaatca
     4201 tcgcaagatg ctcatggcca tgtctgagga catccgcgtt attttggtca aactgtctga
     4261 ccgcttgcac aatatgcgga ccctgaaaca tcttcgaaaa gacaagcagg agcgtatttc
     4321 caaagaaacc atggaaatct atgccccact tgcccatcgt ttggggattt ccagtgtcaa
     4381 atgggaatta gaagacttgt ctttccgtta tctcaatcca acggagtttt acaagattac
     4441 ccatatgatg aaggaaaagc gcagggagcg tgaggccttg gtggatgagg tagtcacaaa
     4501 attagaggag tatacgacag aacgtcactt gaaagggaag atttatggtc gtcccaagca
     4561 tatttactca attttccgca aaatgcagga caagagaaaa cggtttgagg aaatctatga
     4621 tctgattgct attcgttgta ttttagatac ccaaagtgat gtttatgcca tgcttggtta
     4681 cgtgcatgaa ttttggaaac cgatgccagg tcgcttcaaa gactatattg ccaaccgcaa
     4741 ggccaatggt tatcagtcta tccatacgac tgtttatgga ccaaaagggc cgattgaatt
     4801 ccagattcga accaaggaaa tgcacgaggt ggctgagtac ggggttgcgg ctcactgggc
     4861 ttataagaaa ggtataaagg ggcaagttaa cagcaaggaa tcagctattg gaatgaactg
     4921 gatcaaggag atgatggagc tccaagacca ggctgatgat gctaaggaat ttgtggactc
     4981 tgttaaggaa aactatttgg ctgaggagat ttacgttttt accccagatg gagctgtccg
     5041 ttcccttccc aaagattcag gaccgattga ttttgcctac gaaatccata ccaaggtcgg
     5101 tgaaaaagca actggtgcca aggtcaatgg ccgcatggtt ccactgacaa ccaagttaaa
     5161 gacaggggat caggttgaaa ttatcgccaa cccgaactcc tttggaccta gccgtgactg
     5221 gctcaatatg gtcaagacta gcaaggcgcg caataagatt cgccagttct ttaaaaacca
     5281 agataaggaa ttgtctgtca acaagggtcg tgagatgctg atggctcagt tccaagaaaa
     5341 tggctatgtg gcaaataaat ttatggacaa gcgccacatg gatcaagttc tgcaaaagac
     5401 cagttacaag acagaagact ccctctttgc ggccattggt tttggggaaa tcggtgcgat
     5461 taccgtcttt aatcgtctga ctgaaaagga acgccgtgag gaagagcgtg ccaaggccaa
     5521 ggctgaggca gaggagcttg tcaaaggtgg cgaggtcaag gttgaaaata aagaaactct
     5581 caaggtcaag catgaggggg gagtggttat tgaaggtgct tctggtctcc tagtgcggat
     5641 tgctaagtgt tgtaaccccg tgcctggtga cgatattgtt ggctacatta ccaagggtcg
     5701 tggtgtggct attcaccgtg tggactgtat gaacctgcgt gcccaagaaa actacgagca
     5761 acgtctcctt gatgtggaat gggaagacca gtactctagc tcaaataagg agtatatggc
     5821 ccatatcgat atctacggtc tcaaccgtac aggactgttg aacgatgtac tgcaagttct
     5881 ttcaaataca accaagaata tttcaacggt caatgcccaa ccaaccaagg atatgaagtt
     5941 tgctaatatc catgtgtcct tcagtattgc caacctctct acactgacca cggttgtcga
     6001 taaaattaag agtgtgccag aagtttactc tgtcaaacgg accaacggct agttgtccta
     6061 gctcttacta gaaaggctat tatgaaaatc attatccaac gggttaaaaa agcccaagtg
     6121 agtatagaag gccagattca gggaaaaatc aatcagggac ttttattgct ggttggtgtt
     6181 ggaccagagg accaagagga agatttggac tatgctgtga gaaaactggt caatatgcgg
     6241 attttttcag acgcagaagg caagatgaac ctgtctgtca aagatattga aggagaaatc
     6301 ctctctattt ctcagtttac cctctttgcg gatactaaga aaggcaatcg tccagccttt
     6361 acaggggcag ctaaacctga tatggcatca gacttctatg atgctttcaa tcaaaaatta
     6421 gcgcaagaag tgcccgttca gacaggcatc tttggagcag atatgcaggt tgaactggtt
     6481 aataacggac ctgttaccat tatcctagat actaaaaaga gataagaaag accaagccca
     6541 gtcggcttgg tctttctcat cgatcataaa atactccaaa aagaaatcgg ttcttgatat
     6601 gcttggggga agtctctttt caggctttgg cagatgcgat aggaagggat gagatatcct
     6661 aggatgagga gagttccctg aaggaaaagt ggaatatcac ttaaagacac caaggagaga
     6721 atcatcaggc tatcccatag gagaatttgt aaagcaaaac gccagaatct cggtctaatc
     6781 tgggaataga gttaactaaa gtggtcacaa agttggtttg aaagataggt caatagcaca
     6841 ggatgaaaga aaatgagcca accactataa atcaaaatcc agtcccaagt aagcccccct
     6901 tttaaatgtc aaaaatgcca gcatgattcc atcaatgaca aggagttgaa tggttttgat
     6961 gaagatgatt tttttcatgc taaaacctcc ttttttcatc tgttagtgac gtaatgcttt
     7021 atataattat tatacagtat tcagtcggga tatgaaaacg tttactatcg tttttgatat
     7081 aaaaaataga taagaaaacc ctgaaaataa aactttcagg gttggtaggg gacttgagaa
     7141 attagttgat tttctcgaca tagagttgtt ttgcaatgtc catattcact tgtaaatcct
     7201 cgtcgttact gaggatagtg aaggtattgc tgaagccatc aaactgcttg acttggagct
     7261 ggtcaccgat gtgaagtgag tgcttgtcca gataatggag aatgtcaaaa ctatcgtgca
     7321 cccgagtcag gcggtaggcg ccagcttcct tgatatcagc tagtgggagg ttattgattt
     7381 caacgaggag ttctcccttg gcaggaatag ttcctccgtg ggggcaggtt ttagggaaac
     7441 ctagcagttt atctagtctt tccacgaaca ggtcagagac agtgtgttcc aagacctcag
     7501 cttcctcgtg aatctggtca cttgtatagt ctaaatgatg aactagaaaa acttcaatca
     7561 agcggtgctt acgatagagc tcagagacca gtttgagacc gaggtcagtc agtagatagc
     7621 cacattcctt gtcctttagg atgagatttt cacttttcat tcgtttgatc atttcagtta
     7681 cggcaggggg agagacttgc atgcgagccg caatttcctt gttggtaatc ttatgcaggt
     7741 ctatgccaat ttcataaata cattttagat agtcttcttt gtttggggtc attcgtttcc
     7801 tcttgtctaa tatctttatc tagtatatca aaaaaagcta gatttctcta gctgtgactt
     7861 tttatgttat acttattgca agagaaaaaa cgaggagatg gatatgacga aaatagctct
     7921 tctttcagat attcatggaa ataccaccgc cttggaggct gttttggcag atgctcagca
     7981 gctaggagtg gatgaatact ggcttttggg agatattctc atgccaggga caggacgtag
     8041 aaggattttg gacttgttgg atcaactacc gattacggct agagttttgg gaaactggga
     8101 agacagtctt tggcatggtg tccgtaagga attggatagt actcgcccta gtcaacgcta
     8161 tctcttgcgc cagtgccagt atgttttaga ggaaatttcc ctagaagaaa ttgaagtgct
     8221 ccacaatcaa cctcttcaaa ttcatcgtca gtttggggat ttgacggtgg gaattagcca
     8281 tcatctgcct gataagaact gggggcgaga gttgattcat actggcaaac aagaggagtt
     8341 tgaccgcttg gtgactcatc ctccctgtga tattgctgtt tatggacata ttcaccagca
     8401 gttgcttcgt tacgggactg gtgggcaatt gattgtcaat ccgggttcga ttggccaacc
     8461 tttctttttg gacgctcagc tacggaagga cttgcgggcc cagtatatga ttttggagtt
     8521 tgatgacaag ggcctggtag atatggactt ccgacgggta gattacgatg tggcagctga
     8581 attgcagctg gctaaagacc tgagacttcc ctattttgag gtttactatg aaagtctggt
     8641 caatgggatc caccatactc atcatcagga atttttgaga gaattggctc agaaagaggg
     8701 ttgcgatcgg gagttagacg actggttgaa aagtggtaac gattgacatt acaactaaaa
     8761 agggtataat aatagaaaaa gaagagtaga ggcagggtag cctcgtaaaa aggagaagag
     8821 gatgcaaatt ccaagtagat ttaccattgc aactcatatg ctgataatca ttgccctcga
     8881 ggggaaggaa agcaaggtga ccagtgattt tctggctgct agtgttgggg tcaatcctgt
     8941 cattatcaga aagatcttgt cccagttgaa gaaggcagag ctgatttcag tagcgcgtgg
     9001 aacgggcgga acagagattg tcaaggacct taaggatatt agtcttttag atgtttatca
     9061 ggcggtcgaa tgtcttggta agacaggtca actcttcagt ttccatgaca atccgaatcc
     9121 aaattgccct gtaggagctc atattcatga tgttttggat caaaaattgg agagaattca
     9181 gttgactatg gaggcagaac ttggtcagac cagtctagaa aaagtcgtgg ccgatgcaga
     9241 gagtcagatg aaggattaag agggataaat gccctctttt tttctttgga taattatgat
     9301 aaaatgtagc tattaaagga gtaagaaatg tatctcgtta tagaaattgt attagccttt
     9361 atagtgtcat tttggaagga taatagaagt ttgtggaatc cagtattatt tttattatcc
     9421 ctcatttcaa gttattttta tctatcctac cttttttata aaaatggata cgagaatgtt
     9481 cagttagctt tttatgtatt tgcctttgtc ttacttcctt ttttgctttt tctaagtggc
     9541 atctttttaa tctataatgg ggtcattttg ttgaaacgag agggacgttc caagccccat
     9601 tatctctcaa tgctctttga tttttattga ctattagatt ctatttaaaa agacttagaa
     9661 tgcacatgaa agtatgtatt ctaggtcttt tgttttgtat acatttaatt ttcaagagta
     9721 ttatctattt ttccatgcat ggtaacgagt atcaatcaat aactgggtaa ggcgacccaa
     9781 ggtttctctt tcttctggag tgagggattg agcttggaca aagagatgat gaatgtattc
     9841 aagcgccttt aaggaagcca agtcattgat agagctaata ccagcatcaa gaatagtgcc
     9901 aaagaagagg tcgaagtaga gctgaagttc ttcgtcaggg actgtggcca cccattcttt
     9961 aaaggttgtg tctacttgcc ggctatcact gttggtctta tccagttgaa cgaagtgctt
    10021 gtcctcaatc tgccaactaa aggtatcgtg ctgggcgatg ccacccaggg cagtactctg
    10081 aacgatgatt tggtgagcag gaatttccag catcataccg ataatggaac cttgtggaat
    10141 gaatatcttg cttctatcca ttatcctttg ataacccgca gtctgtgtca attcttgatg
    10201 gagaccaggt gcatcaaatg tataaactgc tgtgatctga ttttgcaaac tttgctcaat
    10261 ttggctagca gcatagatag cgagatttcc tcccttggaa tgcccagcca gaataacctt
    10321 ttgcttagga tgatgggcaa aaaagttctt taaatagcga agggcgtgct tttgagcagg
    10381 aatttccttc atataggtca ggtggaaatc ttccttccag ccaatgatac tgtcatctgt
    10441 cccacgaaag acaatcagat aggtatcgag gctgacacga taagtcatag ccgcaaattg
    10501 cttttgcagt tcagggtcga tgtcgttgat aaaatgggag agtttgcaat ttttgaagcg
    10561 cttgtgttga gccaattcat ctaataattg aaggcgattt ttgctagtaa gcatggtggg
    10621 ctctcttgga acctgaggtg ctagatctaa aagacgttga ggaagtgtgg agaccagatt
    10681 atcaaaggag aggtaggtga tttctattaa ggttagaatg tctaactcat tcaagggaag
    10741 gtcgtaataa gaatcatatg cgacatcttt cagatagtca aaaatattgg ccataagagc
    10801 tcctttcttt ttatttatct tagcaaattt ccctcaaatt agctagtagc atagcctgtt
    10861 tgtactggct aaaaacaggc tatttcaaat tcagtttcag accatctagc atggaaaaat
    10921 ctgttataat aatggaaaag gagaagcgca tgcacaagat tttattaata gaagatgatc
    10981 aggtcattcg tcaacagatt gggaaaatgc tctctgaatg gggatttgaa gtggtcctgg
    11041 tagaagactt tatggaagtt ttgagtctat ttgttcagtc ggaacctcat ctggtcctca
    11101 tggatattgg tttgcccttg tttaatggtt atcactggtg tcaggaaatc cgcaagattt
    11161 ccaaggtacc tatcatgttt ctttcttcga gagaccaggc tatggatatt gtcatggcaa
    11221 tcaatatggg ggcggatgac tttgtgacca agccttttga ccagcaggtt cttttagcta
    11281 aggttcaggg cttgttgcgt cgttcctatg agtttgggcg tgatgagagt ttgctggaat
    11341 atgctggtgt tatcctcaat accaaatcca tggatttaca ttatcaaggg caagtcttga
    11401 atttgaccaa gaatgaattc cagattttac gcgtgttatt tgagcatgca ggcaacatcg
    11461 tagcacgtga cgacctgatg cgggaacttt ggaacagtga ctttttcatt gatgataata
    11521 ccctctctgt caatgtggct cgtttgcgta aaaagttgga ggagcaggga ttggtaggat
    11581 ttatcgagac caagaaagga atagggtacg gattgaagca tgcttgattg gaaacaattt
    11641 tttctagcct atctgcgctc ccgtagtcgt ctttttatct atctgctttc tttggcattt
    11701 cttgtcttac tctttcagtt tttatttgcc agtctaggaa tttacttcct ctactttttc
    11761 ttcttgtgtt gctttgtaac catattattt ttcacttggg acatattggt ggaaacgcag
    11821 gtctatcgcc aggaacttct ctatggagag agggaagcca agtctccttt ggaaatagct
    11881 ttagcagaaa aattagaagc gcgtgagatg gaactctatc agcagaggtc aaaagcagaa
    11941 agaaaactga cggatttgct ggattactat accttgtggg tccatcagat aaagaccccc
    12001 attgcagcca gtcaactctt agttgcagaa gtggtcgacc gccaactgaa gcagcaacta
    12061 gaacaggaaa ttttcaaaat cgactcctat accaacctag ttttacagta cctgcgttta
    12121 gaaagtttcc atgatgattt ggtcttaaag caggttcaaa ttgaggactt ggtcaaggaa
    12181 ataattcgta aatatgctct tttctttatt caaaaaggct taaatgtcaa tctacatgac
    12241 cttgataaag aaatcgtgac ggataaaaag tggctgctag tggttattga gcaaatcatc
    12301 tcaaacagtc tcaagtacac caaggaaggt ggtctggaga tttatatgga tgaccaagag
    12361 ctttgtatca aagatacggg aatcgggata aaaaacagtg atgtcctccg agtatttgaa
    12421 cgtggctttt caggatacaa tggccgtttg acccagcagt cctctggact tggcctttat
    12481 ctatctaaga aaatttctga agaactgggg caccagattc gtatcgagtc tgaggtcgga
    12541 aaaggaacga cagtgcggat tcagtttgct caagtgaact tagtccttga gtaaaaatag
    12601 atgagaaaaa gcctccagat tggaggcttt tatgctagac tcttatttct caacgcgtga
    12661 tttgttggcg atatcagcta ggatagcttg aacaaaatta tcaactgaga cagtttgtgt
    12721 ttctttttgg ccgtagcgac gaacgttgac tgtttcgtct tccatttctt tgtctccaac
    12781 aattaattgg taaggaatct tgctggtttg tgaagcacga atcttgaact gcattttttc
    12841 attgcgctca tctacgtctg cacggacacc gcggtcacgg agtttcttgg ccacttccca
    12901 agcgtagtcc acgtgttttt cgttagatac tgggatgagg gttacttggt gtggtgccag
    12961 ccatgttggg aaggccccct tgtagttctc aatcaagata gctgtgaagc gttccatagt
    13021 tgagataacc ccacggtgga tcatgactgg acggtgatct tcgccatcag ctccgatgta
    13081 tttgaggtcg aagcgttctg gcaacaagaa atcaagttgg atagtagaaa gggtttcttc
    13141 ttttccaagg gcagttttaa tctggatatc caattttggt ccgtagaagg ctgcttcacc
    13201 ttcggcttca aagtagtcca cgcccatttc atcaagagct gcacgaagca tggtttgggc
    13261 attttcccac atctcatcgt tatcaaagta cttatgagta tcttgagggt cacgaagaga
    13321 gaggcggaag cggtagtcag tcaagttgaa gtcttcataa acatcgataa tcaactgaag
    13381 ggcacgttgg aattcttctt ggatttgttc tggagtaacg aataggtgac cgtcgttgag
    13441 tgacatttca cgtacacgtt gaaggccagt gagggcacca gatttttcgt aacggtgcat
    13501 cataccgatt tcagcgatac ggattggcaa ttcacggtaa gagtgaacat ggtgtttgaa
    13561 aacttggatg tggtgcggac agttcattgg acgaaggaca aattcttccc cgtcacccat
    13621 gtccatggtt gggaacatgt cttcttggta atgatcccag tgaccagaag tcttgtaaag
    13681 ctcaacagaa gcaagtggtg gagtgtagac gtgttggtag ccagaagcca actctttgtt
    13741 tacgatgtag cgttccaatt cacgacggat agtcgcacca tttggcaacc agaatggcaa
    13801 accttgtccc acttcttgtg aaatcataaa gaggtcaagc tctttaccaa gtttacggtg
    13861 gtcacgttcc ttagcttctt cacgcatttg aaggtagttt ttcaagtctt tcttgtcaaa
    13921 ccaagctgta ccgtagatac gttgcatcat agcgttgtcg ctgtttccac gccagtacgc
    13981 accagctaca tggagaaggt ggaagatttg gatacgacct gttgatggaa cgtgaggtcc
    14041 acggcagagg tctacatatt caccctgacg atagatagtc aaaccgcctt cgtcttctga
    14101 gtgttcttca atcaattcca acttgtaagg gtcatttttg aagatttcac gtgcctcgtc
    14161 tttagtcact tcttcacgaa tagatgggaa gttttctttg acgatttttt gcatttcttc
    14221 ttcgatacga ggaaggtctt cgttagagat ttgaccagct gtgttgtcag tatcgtagta
    14281 gaaaccatct tcgatggctg gaccaactcc caagtgaatg tctgggaaaa gacgacgagc
    14341 tgcttgggcg aacaagtgag ctgctgagtg acgcaagatt ggaagggcat cttcgtgatc
    14401 aggtgtcaca atttcgatgc ttccatcttc agtgatagcg cgagtagtgt cgatgagttt
    14461 gccgttgaat ttaccagcca aggctttttt agctagggaa ttgctgatag attgggcaat
    14521 ttcaaaagtt gttacgccag attcgaattc acgaacagcg ccatctggga aagtaatgtt
    14581 aatcatgatg ttctcctttt ttattatttc atagtttcta agcattgatt ttttatcagc
    14641 agactacttc caagtcctaa cgttcaattg cttttcttta tcagagagga agttttccat
    14701 ttccgtcaga atgtctatat ccaaacgttg agaaagttct aatagccacc agatattttc
    14761 tgaaagtttt tgttccagtg tgtagggtgt ttcatcatag tagcgtcctt gctttgtcat
    14821 caccagtcgt tggaaatttc caatatcatt agataaagcc aagaggtctt cttctaccgt
    14881 ccacttgaaa tcatgatgct taacttccag ttcgtgataa gcttgtcgga ttgcccaact
    14941 gcgctccact aattcttgca actccataat tagtatccta ataaaaaaat gcgacatcct
    15001 cgaaaggacg tcgcaacgtg gttccacctt catttatgta cctcaaaaga gagggacacc
    15061 tctgatcggc tctaacgtgg ccaccgtttt atgttttcat aaaaaactca agagtagtat
    15121 cagtttagac ttcctatgcg tttccagcaa ccacgcactc tctagtagaa agggactaag
    15181 tgacttgtct ctatggatta ttatagcatg attgtgagat ttttcaagga ttttgtgaaa
    15241 gttttttgtt tttcatattt tgtagaatat gcttgatgct aataccagaa tccatgccca
    15301 ccagagcaac tgtttcatag attagcaagt aaattagtat aaactcacca aaggttatga
    15361 tagtaaagta aaagagcagt ccgttaccaa ctaaccatca aagtgagaaa cggaaacggt
    15421 agctatagag taacgataca atcaagatta ccagaggtgt aaagaagaga agattgttta
    15481 tatagtgtaa aggggtcaga aacaactagc aagaacaact cataaagtgg ctaataaaag
    15541 aataatatga ccagatagta ggggagatgg gaatagaatc tacgcatgat aatcacctcg
    15601 ttttaaaaaa acagacaact tagatctctt gctatgatta ttatagcatg tttaaaacaa
    15661 gaaagtaaat ttgttgacaa agaagatttt tcttttcact agaatcatag ttagttttct
    15721 tggtagaaat attttgataa taattaagca agactattga tattgattat taagagtgtc
    15781 acatttgttg taactaaaat aattacaaca atagaggtat aaaaaatgaa actagcagtt
    15841 attgcagcaa atggacaagc ggggaaagca attgttgaag aagcagtcaa acgaggacat
    15901 gaagtaacgg ctattgttcg ttctgaaaac aaaagtcaag ctgagtctat tattaaaaaa
    15961 gatttatttg agttgacaaa agatgatctt actggatttg atgctgttat ttcagcgttt
    16021 ggtgcttata caccagatac gctaccgctc cacagcaaat caatcgaact atttaatcag
    16081 cttcttgctg gaacacagac acgttttcta gttgtagggg agcagaaagt ctttatatag
    16141 atgaaacaaa aacgacacga cttttagata cgtctgattt tcctgaagaa tttaagtcac
    16201 tagcaaaagc tcaagcggat gaattggatc ttcttcgtac aaaaaataat ctcaactgga
    16261 cttttgtcag tcctgctgta gattttattc ccgatggtga aaaaacagga aactacattc
    16321 tagcaggaga aatttttact actaatgaaa aaggaataag ccagattagt tatgcagatt
    16381 atgctattgg attggtagat gaacttgaaa aaggtcatca tataaaagaa cgtatctctt
    16441 tacttgaaaa ataataacta tgagagtatt aatgtttgac agaaaattta aatcttggta
    16501 aaatagggat tgtcgtaaag acaaataact tcttcttggt tacaggcatg ccaacctgtc
    16561 actcggatga agccaaataa aaaggagaaa catcatggca atctcaaaag agaaaaaaaa
    16621 tgaaatcatt gcacaatatg cacgtcacga aggtgataca ggttcagtag aggttcaagt
    16681 tgctgtcctt acttgggaaa tcaaccacct taacgaacac atcaaacaac acaaaaaaga
    16741 ccacgctact taccgtggat tgatgaaaaa aatcggtcgc cgtcgtaact tgcttgcata
    16801 cttgcgtaaa aacgacgtta accgttaccg tgagttgatc aactctctag gacttcgtcg
    16861 ctaattcaag atacaaatgc tgtcaaaagc acaaagcaaa aataggaaaa ttgacgaaga
    16921 aacttcagtt tctaggagat tttatctttt ttgccaagtg cttaggccgt gttcaattga
    16981 gcatatcttg ataatgaagc tactctaaat tgggtagctt ttttgcgttg tcaccttacc
    17041 tcgatatact caagtataat ctttggttac ggttcctagc actgtaaggt aaaataaacc
    17101 agcttttctc ccttcgggga gatttttttt gtttcactga aagtttcgta cgatcttcgc
    17161 ctcgtcgcct agtctataaa cgatttatcc agcaagaatc atgatgctaa gggcgtcaaa
    17221 aatccgtatg aaaataggga aatggcacag tgttcgatga acgcaaggag tttcatcttt
    17281 ttcactagga ttttagtccg ggctcaaatc agctctctga cttcagaggg cttttttatt
    17341 gaggttttat cggtcacaat tttggagact acaaaaacct caaatggtat cagctaatta
    17401 caccataaag gtgcgcagtt actcggcttt tcaagccgag tagctgtatg caagccccct
    17461 agaagagccc actctttaca aagtaaagta tagtatgtta tactttacat ggaagtagtc
    17521 actgaattcc agttagaaat tactttgtaa ctacgttttg aggaggagta aaatgctttc
    17581 ctacgttcga cattacccac tagcgatagc taaattaatg tgtctgtgct ctcctaaaat
    17641 ctgctgattt attactgact aatacaggag gtttttttat gggacagaca atcatatctg
    17701 ctattggtgt ttatatttcc accagtatcg attatttaat tattttaatt attttatttg
    17761 cacaactatc acagaataaa cagaaatggc atatttatgc ggggcaatat ctaggcacag
    17821 gcttacttgt aggggcgagt ttagttgctg cttatgtcgt taatttcgtg cctgaagaat
    17881 ggatggttgg attgcttggt ttaatcccta tctatttagg gattcgcttt gcaattcttg
    17941 gagaagatgc ggaagaagaa gaggaagaaa ttattgaaag attggaacaa agcaaggcaa
    18001 atcaactgtt ttggacagtt acattgctga caattgcgtc tggcggagat aatttaggta
    18061 tctatatacc ttattttgct tcgttagatt ggtcacagac cctcgtggcc ttgcttgtgt
    18121 ttgtaatcgg cataattatc ttttgcgaga ttagtcgggt gttatcctct attccgttaa
    18181 tattcgagac aattgaaaaa tacgagcgaa tcattgtgcc attagtattc attctacttg
    18241 gactatacat catgtatgaa aatggcacga tagagacttt tctgatcgtg tagatttttt
    18301 tgtttcacta ggattttagc ccgagctcaa atcagctctc tgattttcag agggcttttt
    18361 cattgagtat aaatggacaa tcttaaagtt actctattgt agagtggctt ttgatttgat
    18421 taggagattc ttataaatat agtaaaatga aacaaaaaca ggacaaatcg atcgtgacag
    18481 tcaaatcgat ttctaaaaat gttttaagaa gtagaggtgt actattctag tttcaatttg
    18541 atatataaat gaaaacctta gctgtttggc caaggttcat ttcttctatg caagttcttc
    18601 tcttttctta tctgggttcc agatgaagct tgcgataaag ctaaagatga tggttaggat
    18661 agcgaggata atagcaagga tgagggcagg gatgcggata aaccaccaga gtggatttgg
    18721 ttttttatca ttgtgccatt gtttcgtttc ttcgtccaga cgttggaatt ctgtttgaat
    18781 acgattggcg actgtttcaa tgccttcatc attcattttc ttgatatctg agatatcgat
    18841 tggatttcca aagttcatat cgacacgttc acggctaatc aagcccttca aagtcatggg
    18901 accggtgtag gtaaccggca tgatacggac cttggccatt ttggcaatca gtgctgcgcc
    18961 ccccttgaca tcgtttgagt ggcggctacc acttggaaac atgatgagag agcggtcact
    19021 ttttttgaga acgttgatag gatatttgat ggctgaggcg ctgggatttt cacggtcgat
    19081 gggaaaggcg ccacacatac gaatccacca accaaagata cggttggtaa agagttcttt
    19141 ttttgccata aagatgaact gttttggctt ggtcgcaaag gccatataaa caggatccca
    19201 ccaggtacgg tgaggcgcaa ctaaaatata attttcatct tgattaggaa ttttatcagt
    19261 attatgatag tgagcattgc cattgatgga ccataagagc aatacaacta atccacgcaa
    19321 ataagtataa aacatgcgat ctccttcgat tgttttcttg ttattattat accttatcaa
    19381 aggagggctg gcaaactttt cccttgacta gatgcatatt tgggatgaaa ttagaattct
    19441 gttaaaaaaa atgatataat agaatttatg gataaaaata agattatggg attaacccaa
    19501 agagaagtca aggaaagaca ggctgagggt ttggtcaatg actttaccgc atcagccagt
    19561 accagcactt ggcaaatcgt taaacgaaat gtctttaccc tttttaacgc tttgaacttt
    19621 gccattgctt tggcccttgc ctttgtgcag gcttggagca atctggtctt ctttgctgtt
    19681 atctgcttta acgctttttc tgggattgtg accgagctac gagccaaaca catggtggac
    19741 aagctcaatc tcatgaccaa ggaaaaggtc aaaaccatcc gtgatggtca ggaagttgct
    19801 cttaatcctg aagaattagt gctaggagat gtcattcgtt tgtctgcagg agagcagatt
    19861 cctagtgatg ccttggtttt ggaaggcttt gcggaagtca atgaagccat gttaacggga
    19921 gaaagtgatt tggtgcaaaa ggaagttgac ggcttacttt tgtcaggaag tttcctagcc
    19981 agtgggtcag ttttatctca agttcaccat gtcggtgcag acaactatgc tgccaaactc
    20041 atgcttgagg ctaagaccgt taaacccatc aactcccgta tcatgaaatc gctggacaag
    20101 ttggctggtt ttactgggaa gattatcatt ccctttggtc tggctctctt gctggaagcc
    20161 ttgcttttaa aaggcctgcc tctcaagtca tccgttgtaa actcgtcgac agctcttttg
    20221 ggaatgttgc ctaagggaat tgcccttttg accattactt cgctcttgac tgcagtgatt
    20281 aagttgggct tgaaaaaggt cttggtgcag gagatgtact ctgttgagac cttggcgcgc
    20341 gtggatatgc tctgtctgga caagacgggc accatcaccc aaggaaagat gcaggtggag
    20401 gctgttcttc cactgacgga aacttacggt gaagaggcta ttgccagcat cttgactagc
    20461 tacatggccc atagtgagga taagaatcca actgcccaag ccattcgcca gcgttttgtg
    20521 ggagatgttg cttatcctat gatttccaat cttcccttct cgagcgaccg caagtggggg
    20581 gctatggagt tagaaggctt ggggacagtt ttcttagggg cacctgagat gttgctggat
    20641 tctgaagtcc cagaagccag ggaggccttg gagagaggat cacgtgtctt ggtcttagct
    20701 ctcagtcagg agaaattaga ccatcacaaa ccacagaaac catctgatat tcaggctcta
    20761 gccttgctgg aaatcttgga tcctattcga gagggagcgg cagagacgct gaactatctc
    20821 cgttctcagg aagtggggct caagattatc tctggtgaca atccagttac ggtatccagc
    20881 attgcccaga aggctggttt tgcggactat cacagctatg tcgattgttc aaaaatcacg
    20941 gatgaggaat tgattgctct ggcggaggag acagcgattt tcggacgtgt ttcccctcat
    21001 caaaagaaac tcattatcca aacgctgaaa aaagcgggtc atacaacagc tatgactggg
    21061 gatggagtta atgatatcct ggctcttcgt gaggcggatt gttctatcgt aatggcggag
    21121 ggagacccgg caacccgtca gattgccaac ctggttctct tgaactcaga ctttaatgat
    21181 gttcctgaga ttctttttga aggtcgtcgt gtggtcaata acattgccca catcgctccg
    21241 attttcttga taaagaccat ctattccttc ctgttagcag tcatctgtat tgccagtgct
    21301 ttactaggtc ggtcagagtg gattttgatt ttccccttca ttccgatcca gattaccatg
    21361 attgaccagt ttgtggaagg tttcccacca tttgttctga cttttgagcg aaatatcaaa
    21421 cctgttgagc caaatttcct cagaaaatcc atgcttcgtg ccctaccaag tgccctcatg
    21481 gtcgtgttta gcgttctttt tgtgaaaatc tttggaacga gtcaaggttg gtctgagtta
    21541 gaaatctcaa ctctcctcta ttatctcttg gggtcaattg gtttcttatc cgtatttaga
    21601 gcctgcatgc cattcactct atggcgagtc ctcttgattg tctggtcagt aggaggcttc
    21661 ctagccacag ctctcttccc aagaatccaa aaactgcttg aaatttcaac cttgacagaa
    21721 caaacgttgc ctgtttatgg tgtcatgatg ttggtcttta cagtgatttt catcctgact
    21781 agtcgctatc aagctagaaa ataaagaaag actgcaatct gtggattgca gttttttata
    21841 cgatggatct atcgtagatc tgatgtgcaa ggcctacgtg tctattatct atcggtgaac
    21901 ccaagagtga ttctcaagcc tgcttggatt gaggtaatag attcaaatat ctgtagttag
    21961 actatttgaa gtttgatgta agaaagagaa agcgacagat tgaagtaatt ttaactctct
    22021 tctattgcta gaacaaatgg tcggataggt tggtagtttg aaaatgaaga tgcaatctat
    22081 tgttaaatgg aacatagtgt tatttattag aaaatcgttt ggtttatttc ttatcaaata
    22141 cgaaaagcaa cttaaatatt tcaactaaaa tagatgttat gaagaaaagg taaaatgatt
    22201 ttggtatagt gaggttctgt tctatttgat atcatatttt tgataaaaac aaaaatgtcc
    22261 attgcaaagg acaaaatgcg aagtatatta ttttttgaaa gcgatataat ggaatcataa
    22321 aggaggtgta tcgtgtctag aaaacaagaa caaatggaaa cgttgttgct ccttttgcga
    22381 gatagtaagg attatatatc tgctaaagta ttgggagaaa aattaaattg ctctgataaa
    22441 acggtttatc gccttgtcaa ggtaatcaac aaagattgtc cggtagaagc attcatttta
    22501 tctgaaaaag gcagaggttt caaattaaat ccaagaagtt ccctcgtgga cgttgatggg
    22561 aattttacag aggcttttga tcctgaagta aggcgtgaaa aattactaga acgtctcttg
    22621 ttgactgctc ctaagccaca ttctatttat gatttaggag aggaattcta cgtaagcgag
    22681 tcagtagtac taaaagatcg tcagatatta caagagagtc tagcaattta tgggttagat
    22741 ttaaaaatga gacaacgaaa gctttttatt gatggggatg aggctcaaat tcgttcagcc
    22801 attctaaatc tactgccaat gtttaatcag ttggatttag agcaaattac acagaataag
    22861 gttcagcctc ttgacggaga acttgctcac ttttgtttgg gattactgat tacacttgag
    22921 agagaattgg gggtaaacat tccctatcca tataatataa atattttctc tcacctgtat
    22981 atttttatca gtaggaatcg tcgtagtact agtattcatg ttgtagcacc ttcaaaacct
    23041 actattgttg atgagaaaat ttacagtgtc tgtcaaaaaa ttattcaaga aattgaacaa
    23101 tattttaaga tgaaggttga tgcagttgag attgactatc tttatcaata cgttgtatct
    23161 tcgagattgc aaaaaccatt ttcttccggg aagcttcctt tttctcagcg agttttagat
    23221 gtcactcatt actattttag ccgtatgtgt atggacaata gagagattga aacgacagat
    23281 cctgactttg ttgacttggc gagtcatatc agtcccttac tgaggagatt agataataga
    23341 gtacagatta agaatagtct tttatcacaa attcttttaa cctatcctaa tctagttaaa
    23401 gagttaacaa ctatttctaa agaagtgagt ctagtatttg gttttgcgtc cttgagtctg
    23461 gacgagattg gttttctagt cttatatttt gcacggtttc aagaaaagcg agcacgtcct
    23521 ctaaaaacag tagtgatgtg tacatcaggt gtcggaactt cagagctttt acgagcacga
    23581 ttagaaaagc aatttactga attggatatt attgatgtag ttgcttatca tcaattagat
    23641 gagctgataa atctatatcc agatttagat ttcattgtga cgacggtagc tttgcaggaa
    23701 ccagcaagtg tcccgtttgt cctagttagt gtttttctaa ccgagggtga taaacaacgt
    23761 cttcaagcaa aaattcagga gataaactat gaataatctt tcgcttgtcc ttatggatat
    23821 atctgttcaa aatcgtcaag aagcctacaa agaattagca aatcaaatca gccttcttgt
    23881 ttctgaagat acagaaaaaa tagaagagct tctatattac cgtgagagac agggaagtat
    23941 agaggttgct aaaggtgttc ttctaccaca ttgtgaagga aactttcaac atcatgtctt
    24001 agtgattact agattaaaat cacctatcag agaatggtcg aaggatatcc agtgtgttga
    24061 ccttattatc ggtttggcca ttgcagtatc acaggacaag tcatgtatta aaacattgat
    24121 gagaagacta gcagatgaat cattcataaa tcaattaaaa cagttaacaa aagaagaatt
    24181 acgggagata atatatggaa atcaaagata ttcttaatgt gagtctgatc cagacggatt
    24241 tacagatgca gagcaaagaa gaggtttttg aggcattagc tcaactattg gttgagacgg
    24301 gttatgtgtc tgatagagac caatttatcg aaggtctgta tcagagagag gcagaaggac
    24361 agaccggtat tgggaattat attgctattc cccatagcaa gagttctgct gtggagaagg
    24421 cgggggtagt catagctata aatcacaatg agattccttg ggagaccatt gatgggaaag
    24481 gggtcaaagt aattgtactc tttgcagttg gtgatgatac agaagctgct agggagcatt
    24541 tgaagacctt atcactcttt gctcgaaaac ttggtaatga cgaagttgtt gccaaattag
    24601 ttcgggctca gacatctgat gatgtgattg cagctttttg ttaataagaa aaaattttgg
    24661 agggtatccg tatgaaaatt gttggtgttg cagcttgtac tgtgggaatt gcccacactt
    24721 atattgcaca ggaaaaatta gagaatgccg caaaggtagc tggacatgtg attcatgttg
    24781 agactcaggg gacaataggg gtagaaaatg aattgagtca agagcagatt gatgcagcgg
    24841 atgtagttat tttagcagtt gatgttaaga tttctggtat ggaacgcttt gagggtaaaa
    24901 agattatcaa ggttccaaca gaagtggcag tcaaatctcc caataaactg attgctaaag
    24961 ctgttgagat tgttacgaaa taactgaaaa tatttaagga gaaaatatat gttgaaacac
    25021 ttaaacttaa aaggtcactt attgacagcc atttcctatg tgattccaat tgtttgtggt
    25081 gcaggattct tagttgccat tggtttagca atggggggtg gtgttcctga cgctcttgta
    25141 gcaggaaaat tcactatctg ggatgcttta gcaactatgg gtggtaaagc ccttggtctc
    25201 ttgccagttg ttattgctac aggtttgtct tactcgattg ctggtaagcc agggattgca
    25261 ccaggttttg ttgttggtct aattgccaat tctgttggtt cagggtttat cggtggtatc
    25321 ttgggaggtt atatagctgg tttcttggtt caagcgatta ttaaaaaggt caaagtacca
    25381 aactggatta aaggtttaat gccaaccttg attattcctt ttgtagcctc tttggtaagt
    25441 agtttgatta tgatttatat tattggagcg cctatcgcag cctttaccaa ctggttgacg
    25501 agcttattac aaagcttggg aagtgcttca aatggtttga tgggggcagt tattggagtt
    25561 ctcagtgctg ttgactttgg tggcccactt aataaaacag tctatgcgtt tgtgttgact
    25621 ttacaggctg aaggtgtgaa agaaccattg actgctttgc aattggtgaa tactgctaca
    25681 ccagttggat ttggattggc ctattttatc gcgaaattac tcaaaaaaaa tatctatact
    25741 caagaggaaa tcgaaacatt gaaatcggct gttcctatgg gaattgtcaa tattgttgaa
    25801 ggtgtaattc cgattgttat gaataacttg gttccaggtc tcattgcaac aggtatcggt
    25861 ggtgctgttg gtggtgctgt ttctttgaca atgggtgctg attctgccgt gccatttggt
    25921 ggagtgctta tgttaccaac catgactcgt ccagtagctg gtatttgtgc tttgttagcc
    25981 aacattgtag tcacaggact tgtctacgcg attttgaaaa aaccaataaa acatacagaa
    26041 ccagttatga ctgttgaaga agagattgat ttgtcagata ttgaaatttt gtaagagggt
    26101 aacgatgtca agaattgaat tttcaccatc tttgatgacc atggatttgg acaaattcaa
    26161 agagcagatt acttttttga atgataaagt agcatcttat catatcgata ttatggatgg
    26221 ccattttgtt cccaatatta ccttgtctcc ttggttcatt caagaagttc aaaaaattag
    26281 tgacacacct ttatcagttc atctgatggt cacagaccca accttttggg tagatcaagt
    26341 tctcgattta caatgtgagt atatttgtat tcatgctgaa gttctgaatg gtcttgcttt
    26401 tcgtttgatt gataaaattc atgatgcagg tctaaaggct ggtgttgtcc ttaatcctga
    26461 aacacctgtt tctacaatct ttccctacat tgatttactt gacaaagtaa ctattatgac
    26521 tgtagatcca ggttttgcag gacaacgttt tttgaagtct accttgtata aaatccaaga
    26581 actccgtcag cttagagttc agaatggtta tcactacatc attgagatgg atggttcttc
    26641 gagtcgtaag actttcaaac aaattgatgt ggcaggacca gatatttatg ttataggtcg
    26701 cagtggatta tttggtttgg atgacgatat tgccaaagcc tgggatatct gttctagaga
    26761 ttacgaagaa atgaccggaa aaacaatgcc aatcaaataa tggtttgaga agaaatttat
    26821 tagttaggag gaatatatgt cactacaatc agttaacgcc attcgttttc ttggcgtaga
    26881 tgctattaac aaatctaatt ctggtcaccc gggaatcgtc atgggtgctg cgccaatggc
    26941 ttatagctta tttacaaaac accttagaat tacacctgag cagccaaact ggattaaccg
    27001 agatcgcttt atcttgtctg cgggtcatgg atcaatgcca ctgtatgctc tcttgcattt
    27061 aacagggtat aaggatgtat ccatggacga gattaaaaat ttccggcaat ggggatctaa
    27121 gacacctggt catcctgaag tgacgcatac gtctggtgtg gatgcgacat ctggtccgct
    27181 tggtcagggg atttctactg ccgttggttt cgcccaagca gagcgttttt tagctgctaa
    27241 gtacaacaaa gatggttttc ctatttttga ccattatact tatgttatcg ctggagacgg
    27301 tgacttcatg gaaggagtgt ctgcggaggc ggcttcttat gcaggtcatc aagctttaga
    27361 taagcttatc gtcctctacg actccaacga tatctgcttg gatggtgaga ccaaagatac
    27421 tttctctgaa aatgttcgcg cccgttacga tgcttatggt tggcatacag ttctggtaga
    27481 agatggaaca gatttagcag caatttctac agcaattgag acggccaagt tttctggtaa
    27541 gccgagtttg attgaagtga aaacggtaat tggttacggc tcacccaata aaagtggtac
    27601 aaatgctgtt catggtgcac cactaggagc agaagaaaca ggagcaactc gtaagttttt
    27661 gggatgggat tacgatccat ttgaagtacc agaggaagta tattctgatt tcaagacaaa
    27721 tgtagcggat cgtggtcagg aggcatacga tgcttgggct agtttggtgt ctgattacaa
    27781 ggttgcttat cccgaagttg ctagtgagat tgacgctatt gtagctggaa aatcccctgt
    27841 aaccattact gaaaaagact tccctgtcta tgagaatggc ttctctcaag caactcgtaa
    27901 ttcgtcccaa gatgctatta atacagcagc agcagtttta ccaaccttct taggtggatc
    27961 ggcagactta gctcactcca acatgaccta catcaaggca gatggcttac aagataaata
    28021 taatccatta aaccgcaata ttcagtttgg ggtacgtgaa tttgccatgg gaacaatcct
    28081 caatggaatg gctcttcatg gtggtttacg agtttatggc ggaaccttct ttgttttctc
    28141 tgactacgtc aaagctgcta ttcggctatc agccattcag gagttgcctg taacttatgt
    28201 ctttacccat gattcaattg ccgttggtga agatggtcca actcatgaac cagttgaaca
    28261 tttggcaggt ttacgctcaa tgccaaactt gactgttatc cgtccagcgg atgcccgtga
    28321 aactcaagcg gcttggcatc atgccttgac cagtaccacc actccaactg tcattgtctt
    28381 aacccgtcaa aacttggtag ttgaagaagg gacagacttt ggtaaggtcg ctaaaggagc
    28441 ctacgtcgtg tatgataccc cgggatttga tactattatc attgctacag gatctgaggt
    28501 caatctagct atcaaagctg ctaaggaatt ggttttacaa ggtggtaaag tacgtgtggt
    28561 atctatgccc tcaaccgaac tatttgatgc tcaagatgct acctacaagg aagacatttt
    28621 accatctaag actcgtcgtc gtgtggccat tgaaatggca gcgacccaaa gttggtacaa
    28681 gtatgttggt ttggatggcg cggtcatcgg tattgacatc ttcggtgcgt ctgccccagc
    28741 tcagactgtg attgataatt atggatttac ggtagagaat atcgttgctc aagttaagtc
    28801 cctatagaaa ccaattacaa tgaagataca gctgttgtca gactagcaga tgtagtgata
    28861 gacactaatc agatgattgg ttatttaaaa actataatga gaatgtaata atttatctac
    28921 gaaagttata gtagatagta tacacaatag agtataccct gaaacggttg cgaagtacgc
    28981 taatcacttt gctactgatc tagatagttt ctttaatcaa taaacacagc atccacagat
    29041 tgacttagga tattgtaagt tttttgaaag ctagagagaa ggtctctaaa attaaaaaac
    29101 gcatagtata ggatgttgaa atgatgaact gccccc
//
LOCUS       DAVLDI010000024        28400 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLDI010000024 DAVLDI010000000
VERSION     DAVLDI010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.024"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VXD01_001079"
     CDS             complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VXD01_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV0601499.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
     gene            complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VXD01_001080"
     CDS             complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VXD01_001080"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV0601500.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VXD01_001081"
     CDS             complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VXD01_001081"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV0601501.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3790..5058)
                     /locus_tag="VXD01_001082"
     CDS             complement(3790..5058)
                     /locus_tag="VXD01_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV0601502.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGELTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5178..5546)
                     /locus_tag="VXD01_001083"
     CDS             complement(5178..5546)
                     /locus_tag="VXD01_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV0601503.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5539..5805)
                     /locus_tag="VXD01_001084"
     CDS             complement(5539..5805)
                     /locus_tag="VXD01_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV0601504.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="VXD01_001085"
     CDS             complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="VXD01_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV0601505.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLMSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9373..9942)
                     /locus_tag="VXD01_001086"
     CDS             complement(9373..9942)
                     /locus_tag="VXD01_001086"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV0601506.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDEYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10013..11128)
                     /gene="ychF"
                     /locus_tag="VXD01_001087"
     CDS             complement(10013..11128)
                     /gene="ychF"
                     /locus_tag="VXD01_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV0601507.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11248..12414)
                     /locus_tag="VXD01_001088"
     CDS             complement(11248..12414)
                     /locus_tag="VXD01_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0601508.1"
                     /translation="MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQAQIDFEKGGATVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKFKIDKYLL
                     PAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYAVSLQAIP
                     FNPARDVIVPRRKEKEGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLYKTLLATG
                     LRIRECLALKWSDIDLKNGTLDVNKTLNIIKEITVPKTKSSIRVIDLDNKTVLMLRLY
                     KARQSQIGKEMGLTYEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFHAFRHTHA
                     SILLNAGLPYKEIQTRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEKLKSS"
     gene            complement(13120..13788)
                     /locus_tag="VXD01_001089"
     CDS             complement(13120..13788)
                     /locus_tag="VXD01_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000666925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HEV0601509.1"
                     /translation="MKFCPECGNSVVGCKFCPNCGYSINASLKTTPQKVATPSSRPST
                     VRSKRTDKVGPLEIDKNHRTYRIHGARKAKGSSGLIGGTAKVVGKTTLALGTGGLSLI
                     PSLIKKDKNDTDWYSFDDLVSYELVINDQSVVSGGVGQALVAGAVFGVIGAVAGGIVA
                     KRKATTKILNMTIRITSNDFTKPVVFIDLIKKPVKNTSKEYKEAIENAQKIIGALDVI
                     THNS"
     gene            complement(13807..14523)
                     /locus_tag="VXD01_001090"
     CDS             complement(13807..14523)
                     /locus_tag="VXD01_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0601510.1"
                     /translation="MADNIKRLLSAKGLNPRQLAIALDFKYTTVNDWVNAKTYPRIDK
                     IEMLANFFNVSKSDLVENKNAETPTTSPIQSIYDQLTPPRQEKALTYLKKQLLEQKNE
                     NIVSENIISLDDYRESKTLPVIGVVTAGNGITQDDNLNIEKCFYTDEIPDDYDAIAYV
                     VGNSMEPKIKNGDYLFIKNTPQVDYNTIGIFQVDGANYVKKLRQGYLESLNPECADIQ
                     LDESNDIRTIGEVVGIYREK"
     gene            14727..14918
                     /locus_tag="VXD01_001091"
     CDS             14727..14918
                     /locus_tag="VXD01_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001241280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0601511.1"
                     /translation="MRLTLKALRANSNMKQSEVAQKLGISTTTWSKWENGKSFPDVAQ
                     VKEIEKLFGVAYDDIIFLS"
     gene            14993..15370
                     /locus_tag="VXD01_001092"
     CDS             14993..15370
                     /locus_tag="VXD01_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601512.1"
                     /translation="MLYHWGLTFSEEISDLEHKGENNMNNKQVYQAQTTDHGIARALG
                     EEIRMITDVEETTYNGHGEIIVEYTSDVALTKLFDRIKALYEKGESYETKPFLHFKVL
                     EDDIEPSPNGVFTAKEVAEFLGI"
     gene            15392..16018
                     /locus_tag="VXD01_001093"
     CDS             15392..16018
                     /locus_tag="VXD01_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEV0601513.1"
                     /translation="MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESF
                     GKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVRKFKMNLVKAFFEMREELS
                     KFRMQRALEKPKRKTLHDSIENWEQAPKHAHSTMNNLLLKAVTDRNAKQLREERGGYN
                     GIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSA"
     gene            16288..16461
                     /locus_tag="VXD01_001094"
     CDS             16288..16461
                     /locus_tag="VXD01_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000130088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0601514.1"
                     /translation="MTDKIKKVGRPKGENSNTVKLTVRVSEQLNSKLEEYGKKNGLTK
                     PETLRKAFENLTK"
     gene            16615..17022
                     /locus_tag="VXD01_001095"
     CDS             16615..17022
                     /locus_tag="VXD01_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601515.1"
                     /translation="MGKQVFTQEILRNIQEENGIITVDLILDALPTWSEKAIKGRLSN
                     WRYRKVIDYRVEDGEFSEIFLLRSKQEIKEEVSAGQRLKMDLYFRQVLALTGIIESNT
                     SKDNDKTKAIELQQKAMRAIPDDIYKELSEIYE"
     gene            17516..18016
                     /locus_tag="VXD01_001096"
     CDS             17516..18016
                     /locus_tag="VXD01_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601516.1"
                     /translation="MIADQLKAISTNLEEIQEILVGDGTALAKREISRVLNDLDDVYN
                     ELTSTEYREQQETLKEQTERMKQRVVAEVIGGLEEREESYYRNYWGDTKFIKLLSNFD
                     GFLFLNTYLAEITKENTYPMEQSQLLNYVWEVIAVDIAKKKRGKKNVLDSWTDSSLYT
                     RGMMID"
     gene            18028..18168
                     /locus_tag="VXD01_001097"
     CDS             18028..18168
                     /locus_tag="VXD01_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601517.1"
                     /translation="MTLDLGKMTQAEFDEVMADIKARNPNLLQFITDFLDRKVTPGEV
                     DD"
     gene            18230..18445
                     /locus_tag="VXD01_001098"
     CDS             18230..18445
                     /locus_tag="VXD01_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601518.1"
                     /translation="MNELDISNTQAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTI
                     KTPSEDLNPEYGRYIQLAGVNVWGGME"
     gene            18442..18738
                     /locus_tag="VXD01_001099"
     CDS             18442..18738
                     /locus_tag="VXD01_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001106820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601519.1"
                     /translation="MSYIVKIYLDSEKIPDEPYFTKEIFLATCMGNATKLAVTMGLLT
                     KQVLDLETKTAILKALDTIIETQKAILQGVASGQITFVNKSKREEELDEPIRER"
     gene            18716..19057
                     /locus_tag="VXD01_001100"
     CDS             18716..19057
                     /locus_tag="VXD01_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0601520.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGSEISLTTKLTERTVRDIIKR
                     LVVKHNIPIVGVRCGVFSGYFIPANKGELLDGAKAFYNQVQEESKRLAVLMNSDLESY
                     KETLKEVGGYV"
     gene            19050..19323
                     /locus_tag="VXD01_001101"
                     /pseudo
     CDS             19050..19323
                     /locus_tag="VXD01_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492129.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            19320..20180
                     /locus_tag="VXD01_001102"
     CDS             19320..20180
                     /locus_tag="VXD01_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEV0601521.1"
                     /translation="MTIYEARGFQSNLVYPFDKIEPFQYIERFKPLVVPESADTEEYK
                     RTQAPYCLSGKVMPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTTEDFIEAVSSALFGY
                     SYILYPTIKHSIEKPRFRLVVKSNNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPATYQKIVEHGLDYPVPKVEPRAKQGTTERYKPRVSGQRSMTMRIIDTLF
                     NGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTFSS
                     IARAEYRKRG"
     gene            20260..21714
                     /locus_tag="VXD01_001103"
     CDS             20260..21714
                     /locus_tag="VXD01_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEV0601522.1"
                     /translation="MWELYSRIWELGDQWRKENSYIVNEGKKNERVEIPRPSVAIVAK
                     ALQEICHFTFIGEGVISDISKLYLYHLDLGHYVSSNDIFRKLLLKYDSRLTSNKFFLE
                     LISYIRTETKMKPPLDDYRYIPVANGVYNIKTHKLEEFSPNFVITSKIQTEYKPCARK
                     PILDGWFDFDRWLEALAVNDKEVVALLWQVINEAINPNRTRKKMVLMVGDGNNGKGTF
                     QSLLENLIGRSNISNLKPDQFGKEFYLGALEGKVCNIGDDISNKYLDEVSDLMSVISG
                     DPVQVNKKSLQPVEARFRLLCIFSGNDLPRARNKTMGWYRRLCIIPFRADFNGQKERH
                     EIKDRFIKNKELLEWVLFKVLNMPDFDSFIEPEAVQKMLSKYKNDNDYIKVWVENFYI
                     PNGWHEINHVPMFIARNKLKEFAEDIGIDKPKLGQFSNAVMAELEKTTSYKYSAKNGT
                     VSSKFYDVLDPQGFQRKRFVKGIWGIHLEDEDLG"
     gene            22315..22839
                     /locus_tag="VXD01_001104"
     CDS             22315..22839
                     /locus_tag="VXD01_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601523.1"
                     /translation="MTLKTFSDKAKTFNFTYEFKDQDTAQVAGSALMGYMIGTYVVPS
                     ISITYKNKGTLVAEYVEDHKLNKTFKRICDGFKDYYKQPEGDEAFEERYKRERVLQLK
                     ESEDFESLLNKVTDYELKLLDYAERLLSDKPILMNSMTAFGTLEVLGNESINLFQKLD
                     VEGEYKGLADYSGQ"
     gene            22902..23168
                     /locus_tag="VXD01_001105"
     CDS             22902..23168
                     /locus_tag="VXD01_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601524.1"
                     /translation="MVRSLKARLEKLEEYAGKTEYATTDECISLYVDCLRFAFQQDEI
                     KIDMDDFIKTPFKDIKLADYKKSKKRMDELREMTGISEFSELEQ"
     gene            23219..23560
                     /locus_tag="VXD01_001106"
     CDS             23219..23560
                     /locus_tag="VXD01_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000035041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEV0601525.1"
                     /translation="MANYLMTGNVKKASELSEITRKTAYNYLNDATFKRIYRERRSEQ
                     LKESTTLLQNASVEAVNVLREIMLDKTVSPYARQQSAQSILNMAYKAVEMVEVVEQLE
                     ILEAKILDEGD"
     gene            23547..23798
                     /locus_tag="VXD01_001107"
     CDS             23547..23798
                     /locus_tag="VXD01_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601526.1"
                     /translation="MKAIKNRLNKLNKLAVVDEVDTVFLTQIDTGHFEVRYRIGGKNP
                     KDIIEVYPTKEEAEKAISEIKNTKGLRIFWDNLALLEDN"
     gene            complement(24237..24578)
                     /locus_tag="VXD01_001108"
                     /pseudo
     CDS             complement(24237..24578)
                     /locus_tag="VXD01_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117663.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
     gene            26013..26198
                     /locus_tag="VXD01_001109"
                     /pseudo
     CDS             26013..26198
                     /locus_tag="VXD01_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255647.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            26480..26638
                     /locus_tag="VXD01_001110"
     CDS             26480..26638
                     /locus_tag="VXD01_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601527.1"
                     /translation="MIEDFLIDLENIQLEDMEIDFNMEIDIDLNIDFEIDVDLDGLDL
                     TLLQELEA"
     gene            complement(27070..27264)
                     /locus_tag="VXD01_001111"
     CDS             complement(27070..27264)
                     /locus_tag="VXD01_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV0601528.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(27329..>28400)
                     /gene="dnaN"
                     /locus_tag="VXD01_001112"
     CDS             complement(27329..>28400)
                     /gene="dnaN"
                     /locus_tag="VXD01_001112"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV0601529.1"
                     /translation="SSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNEDAG
                     LLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQYP
                     RIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDS
                     HRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISF
                     YTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGV
                     VSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRP
                     FTLVPADTDEDFMQLITPVRTN"
BASE COUNT         9184 a         5267 c         5122 g         8827 t
ORIGIN      
        1 tttcgtcatt catttttgac tttacttcat cataggatag tgcatgagat tcctcttcta
       61 ctgcttcagg catctttcct gtttcgtaaa gagctttaat ttgtgtacta tccaatgttt
      121 cgtatttcaa taatgcttct gcaattaact tgtgagtttc acgatttgac tgaataattt
      181 cagcagcttt atttcgtgcc tcatttaata atgaacgaac ctcttcatca atttcataag
      241 ctgtttgttc tgaaattgat ttttgaggac tctgtgcacc aagcatagca tggtttcctt
      301 catattgtac tgggccaagt ttttcactca taccgtactc tgtaaccatt gcacgtgcca
      361 tttgtgtcgc ttgttcaaag tcgtttgaag ctcctgtagt ttggacatta aagataattt
      421 cttcagctac acgtccaccc attaagccag ccaattgctc tttcatatct tctttagata
      481 gaagcatttg atcctcttta ggaagtgcaa tcatgtatcc gcctgcacgg ccgcgtggta
      541 caattgtaac cttatggaca acgcgagcat tcgacaagac tagaccaaca atggtatgtc
      601 ctgcctcatg gtaagcaacc aattctcgtt ctttttgtga aactgtctta tctttcttag
      661 aaggtccagc aataactcta tcttctgctt catcaatatc tgaagcatca attatcgatt
      721 tattgcgacg agcagcaact aaagctgctt cattcaagac attctctaaa tcagcaccaa
      781 caaagcctgg agtttgttga gccactaatt tcaaatcaac atcttctgct aaaggcttgt
      841 tcttagcgtg aactttcaag attgcttcac gacctttaac atcaggacgg ccaaccaata
      901 cttttctatc aaaacgtcct ggacgcaaaa gggcaggatc aagtacatct gaacggtttg
      961 tcgcagcgat gacgataatc ccttcatttc cctcaaaacc atccatctca atcaaaagtt
     1021 ggttcaaggt ttgttcacgt tcgtcattac ctccgccgag accgactcca cgttgacgtc
     1081 caacagcatc aatttcatcg ataaagatga tagctggtgc tgcttttttg gcatcctcaa
     1141 aaagagagcg aacacgacta gctccaactc cgacaaacat ttctacaaag tcagaacctg
     1201 agatactaaa gaatggaaca cctgcttctc cagcgactgc cttagcaagc aaagtcttac
     1261 ctgtccccgg aggtccctcc aaaagaacac ctgctggaat acgggctcca agttttgtga
     1321 atcgttttgg atcttttaag aactcaacaa cttcaactag ttcttgtttt tcttcctcag
     1381 ctccagcaac atctgaaaat cttactttaa tatcttcttt atttgctgct ttagccttac
     1441 tacgtccaaa actcattgga ttacggccat tgcctcctcc catatttccc atcatagaga
     1501 ataggaagaa gaatagaatt ccaaatggca caatggatac gagtagatta atccatatac
     1561 cacttgaact ttcatgctta acagttactt ctgctttatg gtcagtagca agtttttgca
     1621 attctgatac ggtagtatct gcaggaagaa tagtgctggt aaatttctct accttagtaa
     1681 cagatggcgt gaaaaactga atacctgttc cttctttact tgttttagga tttttataga
     1741 caccagaaac ttcgataaca ctaccatttg gttggtaagt taattctttt acattaccat
     1801 cggtaatttc ttgtaccaac tcagtatagt tgatttgctg acttcctcct gagttattcc
     1861 cagaatagaa atactggaat cctgtcacaa ggaaaaagat aaataataac catagaaaag
     1921 gatttttaat taaaccatta ttttgttttt tcattaaaga ttattctttc taatttgaat
     1981 acacttcctc tttcaatact ccaatataag gaagattacg ataattttct ttgtagtcta
     2041 aaccataacc tactacaaac tcatttggga tagtaaagca ggtatagtct gcctcaattt
     2101 ctacaacacg tccttctggt ttatccaaca aggttgcaat tttaacagaa gctgcttctc
     2161 ttgctttaaa catatctcgc aaattcttca aagtttgacc tgtatcaatg atatcttcta
     2221 caaatagaac atgtcttcct ttgatatctt gagtcacatc ttgtttaata ttgataacac
     2281 cactacttgc tgttccacca tggtagctag aaaccatcat gaagtccatt tcaatatgtg
     2341 tatcaatatg tttgaccaat tcagccataa aaggaataga tccttttaaa atcccaacta
     2401 agattggatt ttttcctgca taatctttag ttaattgagc acctagtttt ttagctgctt
     2461 ctgtaatttc atcgtgtgaa acgaggactt ttttaatatc gttttctaac attttttacc
     2521 tatctatttt ttctatataa agtacagtgt tcattatatc atttttcgtt tttttactca
     2581 aattattggt cgcaattccc aaaattgaga caatttcacc aaattgctca ataataagag
     2641 cagagtttct cttttccata gggattttca aatcaataaa taaacgtctg agtttttttc
     2701 tatgcccatt ttgaatcaaa acatctcctg tttttcgatg acgaatgtgt atggatgttt
     2761 cacgtgaaac aggtatttgt tgaattgatt caccttctaa tggaagtcca aaggaaaata
     2821 aatatccttg ataagctacc tgattttgat agtgtaacac aagttcatct tccttttcat
     2881 cagcctgcgg actgatttta caaatctgaa actgttggta ctcttttatc aattcatagc
     2941 catttttaat cggatgacga tactggcttt tagattttaa aatctgctga acttcagcaa
     3001 actgagcttt tgtaagattc aaatctggaa aacgattcag ataagtttga agtaaaactc
     3061 tttgtgtaga ctcagagtaa gaaaataact gctgtaaatc ttccacatta atattgttag
     3121 ataattcagc tattgccaaa tcataatcta aaatttcatt gccaatgcct aagattgcat
     3181 ccctaaatcg aggattttct ttttccaatt ctggtaagta agagtttcga atacgatttc
     3241 gaaaataatg attctcctga tttgatgtat cttcaaagtg aaaaattgat ggaaagtctt
     3301 ttttctgaaa atgcaagaag ggacgaatga tttctatctc tccgactact tgcttctcct
     3361 taattcctga tagatagcgc aagcgagttc ctcgaatcaa gcgcatcaaa atcgtttcca
     3421 cctgatcatc agcatggtgg gcagtgacta aagctgtcgc acctgtcttt ttcataacct
     3481 cttgaaaaaa atcataacga aaatttcgtg cacgcgcttc tgaaaattct cctgaaaaat
     3541 tgctgatata aataggaagc tctgcttcag cagccaactt ccttaattcc ttttcttccc
     3601 aatctgattc aattctctgc ttatgattca catgagccag aatcaattca atctctaact
     3661 ctttttgata agtagacaat accttaaata gaaacataga atctaatcca ccagaaagag
     3721 ctagaaccgc cttagcatgc tttttgaaat atcccttctt gagaaaatga tttaaaaaat
     3781 ctggttccct cattttagaa cctcataaac atccttggct atcttagaaa tcgtatcata
     3841 atcagaattc ttagtgaaaa tagaaagaat aaatggagaa tctgcataga caacacccgt
     3901 atcatgctta aattcatccg catctccaat tttatgagct actttaacag aaacaccttt
     3961 ggcaattcgc tgactatcaa aatctgtttt agtcaaagac tctagcacaa atccattttg
     4021 attataaata gcttccataa acttcccggc catcttagaa gaaatcaatt tttcttttgg
     4081 atcccaatca tctcccataa tggcagacat tttggatttg aatgtggcat cagattggtt
     4141 tgaaatgtaa tatcccaata gattatgagc tacattatca gattcttttg atactttcgt
     4201 aattaaatcc tttaaagaat attctttatt atcttctttt ttaggaagac taccacttcc
     4261 ctctggttta taagaacctg gaaaatcatt gactgcagat acgtatttta cagtcgtatc
     4321 taactgataa agaccctcat ttattttttc ttgcgtataa tagagatagg agagtttcaa
     4381 aacgctggct gcatacatct tttcatcttg attgatacca gcttcttttc cagtagtcag
     4441 ttgcttaaca taaatagaga aagaatcttt ctgatatttt tcagataaca tttcttgaac
     4501 tttactcatc cgattatctt cttcagaagt tgattcttta gctacccatc cagcctgatc
     4561 aatatgtaga aattctcttc cttctacaaa catggtcttg tcgattgata cttgcgaata
     4621 agctgataag gatgatttca cttcttttaa atcataagga ctattgtaca gtttaaagtc
     4681 agattctaac catacttttt ttattgttgg agttacctct gattgatcat ataaaaatcg
     4741 tttgtccgca gctataaatt gatgatttga tagcttaaat actggaatcc cttgtttatt
     4801 taagcgccac tcggttattt gaaaacttgt tttgggagtc aattccccag attccactac
     4861 taaatcttca ttcgcataaa caggaacctc tccataaacc atgggagaac ttaatttttc
     4921 tctaaaataa ataccaaagt cagattgtga aaggtaataa atttctttcg aagtatagac
     4981 gacttctttt tctgtgctaa cgacttttga aatggtcaaa aaacttggta gcaacaaaat
     5041 aattaagaat ttacgcattc ttcctttcct tttcttcttg taaacgcaat aattgatttt
     5101 tatcagccaa ttcttccaac ttttcatctg acaaacccaa aaattgctct attacgtcta
     5161 ataaattttc cattttatca cctttgaagc aagtcaggaa tcgtataaac tttttccctc
     5221 gacttagaat aatagtactt cgctcgtgta tatttagcag cataatcttc atctttcaac
     5281 ttggtagcaa atgctgtctc cttatccttt tcatcactca aagtttgata ctgagtttgc
     5341 aagtctgcta attgctgacg tctttggagt aattgctgat aactctgcgc taaattaaaa
     5401 gttggcaaga taaataatag cataatcaaa atcaataccc ctcccataaa acgattccgt
     5461 ttttgtcgtt ctttcatcag gtagcgacga cgttggtatt cattttgaat aaaagaatta
     5521 ttcaattgta caatattttt agacattttc ttctacccgt gtttcactga taatttcata
     5581 cattcctgct gcatcttctt tttttgtact atctttcatc tctagtactt ttacaagcag
     5641 caacttattg ccaaagcgaa tttcaacttg gtcattaact ttcaagtccg ttgaactttt
     5701 ggccaagatt ccattaacct tgattctacc tttatctgct acttcctttg cgactgtacg
     5761 acgcttgata attcgcgata cttttaaata tttatctaat ctcatcctta ttacctcaat
     5821 ttattattgt accattttta tctattttat agaagaaaaa tatcaaatgg aattttcttc
     5881 cttagactct tttatctcta ataaactttc tccaaaaatc agcagacctt ctaaaatttc
     5941 ataatctttc ttattttgaa catcaaatac aagctccatt aattccttat tctcagcgat
     6001 gcctgctttt aagttcgtta cggataaagc tttaaaataa tcttgagcta aaaacagtcg
     6061 ttgagtgact ttttcaaatt gaattgtaat tttattatct tttctttcca cacgttgaac
     6121 aaagaccttg tccaagtatg atttgaccaa accaatctct aaaagatagg ctactacatc
     6181 tgggtattct ccaaaacggt ctatcaactc ctcttgtaac tcttcataat tgacacggtt
     6241 gtcaatttga cgaattttct tgtaaatttc aatcttatgt cgttgatcag aaatataagt
     6301 atcaggaaga taggcatcaa tttgcaaaat caactcagca ttccctttgg ttcttgtgtt
     6361 agcgttagca ttaccgtttc gtttagcaat agcttcctct aataactgcg aatacaattc
     6421 aaaaccaaca gaatcaatga aaccagactg ggattttcct aaaagatttc ctgctccacg
     6481 aatcgaaaga tctcgcattg caatcttaaa gccagagccc aattctgtaa atcctttaat
     6541 cgcttctaat ctcttttcag agacttcact gattgatttt tctggacgat acatgagata
     6601 agcataagca atacgattac tacgaccgac tcttcctctt aactgatata aggttgacaa
     6661 gcccatatgg tccgcatttt caataaataa agtattagca tttggaatgt ccacccctgt
     6721 ctcaataata gtagtcgtca ccaagatatc gtattgtccc tcaataaagt ctaatagagt
     6781 attttccaac tggacttcac tcattcgacc atgaacatat ccaatcgaag cctccggaat
     6841 caactcctgt aattctgaaa ccttctgaac aattgtgtca actttgttgt aaagataata
     6901 aacttgacct ccacgctcca tttcacgcaa gacagcatca cgaatgacac tatcattctt
     6961 ttccaaaaca taggtctgaa caggatagcg attagtcggc ggagtttcaa taacagataa
     7021 atctctgatt cccagcatag acatatggag ggtacgaggg attggcgtag cggtcaaggt
     7081 taggacatcc acttgtttct tcagttcttt caaagtttcc ttatgcttga caccaaatcg
     7141 ctgttcctca tcaataatca tcaagcccaa atcagcaaac acaacatctt ttgacaaaac
     7201 acgatgtgtt ccaatcaaaa tatcgacttg accgtttttc aatttttcaa gtgttgcagt
     7261 ctgctctttt ttacttctaa agcgactcaa cacatcaata ttaactgcaa aattttggaa
     7321 tcgttcctta aaattcgtat agtgctgttg cgctaaaacc gtcgtcggaa ctagaatgac
     7381 aacctgtttg tgatcattga ctgctttaaa ggctgcacgc atagcaactt cagtctttcc
     7441 aaaaccaaca tccccaacta aaagtcgatc cattggctga gaagcctgca tatccctctt
     7501 gatttcctca atactacgaa gttgatcatc cgtttcaaca taagggaaag catcatcaaa
     7561 ggcatcttga tcatcatcat cagctgagaa agcaaaaccc ttcaactgac tacgttcaga
     7621 gtagagtttg attaaatcat cagctatatc ctctacctgg ttcttaacct tttgcttggc
     7681 ctttttaaaa tgaccgtcat ttaatttatt gagttttgga gctttaccat cacttgaaat
     7741 atatttggac agtagatgaa tctgttccac gggaatagaa atttgatcac cattttggta
     7801 ttggacactg acataatcac gatgaattcc cttgatttca atggtttcaa ttcctagata
     7861 ttgaccaatc ccatggatat gatggacaac atagtcccct ttttcaagtt cattgtaatc
     7921 ttttaatctc tctgcatttg aaacatgttg tcttcgaaaa cgacgcttta atttcttttg
     7981 aaaaatctca tgttcagtta tcaataaaat cttttcatct acaaaatgaa aaccatgtct
     8041 gagattaccc tctattaagt ttacagattc tttacagata tttgtcttat ctctagaatc
     8101 caatttaatc tgatattcct ctaacatatc ctccaatgtt ttacttccca ttgaattgct
     8161 agactgcaga ataatggtgt aatccatttt tttatatcgt tcaatttctt cttttagaaa
     8221 agaaaactga ttgaaaaatt cctgcatagg atattgattg aattgataaa ttttgtcaaa
     8281 tttgagattt cctaaaccct tttgaagatt agaaaaaaag gtcactggac tttgtttttt
     8341 atagatttgt tcaatatcag aaaaatactg catatcagaa aatgctttac tattctgtaa
     8401 ttcttctgta aagtactgcg ctaattctct ttcaaagact tcatactgat tcatcaattt
     8461 ttgataatca tcaaagaata ttggagtatc tttttcaata taatcaaaga cagtccatgt
     8521 cttatcatag cacaaagata aaaacttccg agagtctgca tgactttgtt tttggtgaaa
     8581 acttgaaaga atttcttcta ggtatgattt caaaataggt gataaagttt ttgaaatttg
     8641 tttttctaaa gctgactgtc ctcgttgata atccttttct ctcaaaagca tatcactagc
     8701 tggaaagata gtgagttctg tcttattttc tttcgataat tgtgtttcta cttcaaatga
     8761 cctgatacca tcaatttcat caccaaaaaa ctcaattcga caaggttcta actgggatat
     8821 ttcaaaaata tctaaaatat ctcctcgaag actaaattcg ccctgagttt gtacttgagt
     8881 aacttttcga tagccatttt cctttaactg atggataaac gcgtgttgat catattcttc
     8941 accaactgag atttttacaa tactatcttt gaatgcattg ggagacggta aaatcaatcg
     9001 acttgctgcg atattacaaa ctaaaatccc tttcttagat gaatcagtca aaaaacgcaa
     9061 ggcttcaacc cgtgaaataa ttttttcctg tgaagacatc aaaaactcca ccataggagc
     9121 atcatctacc aaaaatggat agacgagttc ctcacccaag atagatataa gatcactaac
     9181 aagtccttct gcttctccat aagttgacat caataacaca atcctatctt ctttttctaa
     9241 actgcttgca attgcaagag ccttagtaga tgttgataaa ccaagtatta gttgtctttt
     9301 cttatctgtt aaattttgat gccatttttt aatctgatca ttttctgaga ataaatctaa
     9361 taaggtcacc atttatccgt tatacctctg cattgttttc tcaaaatttt tctcttgtaa
     9421 atagtagttt acagaatcgt caactttgtc aacagactgt aaaataccga tatactcatc
     9481 cctgtcaaac ttactcaaaa catgatgaac aactgacata ccatttttag gtcttccaat
     9541 tccaatctta acacggttaa agacctgagt tcctatatgt tgaataatag acttgatacc
     9601 attatgacca cctgctgagc cttttgctct taaacgaatt ttcccaactt ccatgtcaag
     9661 atcatcgtaa atgataagta aatcgtcaat atccaaacca tagtaagtta ataaagcatg
     9721 aactgctttt ccactttcat tcataaaggt cgttggttta accagataaa ttttttctcc
     9781 atttaggaaa aaggatgcta ggtcagcttg aaatatctta tcgtgtgtaa aagtgacatt
     9841 ctgtttcttc gctagttgat caatcaacat aaaaccaaca ttgtgttttg tttcaaaata
     9901 tttatcccct ggatttccca agcctacaag taatttggtc atttattttt cctttcaaaa
     9961 gccaaaaggg ttggaatttt tttccaacct aattgacacc atttattaat ttttagacat
    10021 taaagcggaa ttccatgata tcgccatctt gaacgatata ttcttttcct tcttcacgca
    10081 agcgtccagc ttcttttacg gccttttcag atccgtattt cactagatct tcatatgaca
    10141 tggttactgc acgaataaag cctttttcaa agtctgagtg gataatacca gctgcttgag
    10201 gagccttcat accacgtttg aaagtccaag cgcgaacttc tttttcacca gctgtaaagt
    10261 aagttcccaa tccaagcaag tggtaagctg cacgcgtcaa cttatctaca cctgattctg
    10321 tcaaaccaat ggcttcaaga aactcttttt tatcttcatc atccaattca gaaatttctt
    10381 cctcagcacg cgcagaaata acgactactt cagcattttc tgtcgctgca aattcacgaa
    10441 tttgtttgac atagtcgata gagtcaggtt ctgaaaccac atcctcgtcc acattagcta
    10501 cataaagaac tggtttagtc gtcaaaagga aaagaccttt gacaaccttt tgttcctcat
    10561 ctgtaaattc aatggtacga gctgatttcc cgtcttctag gactggttta atcttttgaa
    10621 gaacattaaa ttctgctact gattctttat ctttttgcgt acgtgccatc ttttctacac
    10681 gcgcatatcg tttgttcact gattctaagt cagcaagaat taattccaga ttaattgtat
    10741 caatatctgc aagtggatct acaaaggcgt cttcacgtcc ttgctcgcgc atcacatttt
    10801 catcatcaaa agcacgaact acgtgaacaa tcgcatctac ttcacgaata ttggccaaga
    10861 atttattccc tagcccttct ccttttgaag ctccttttac aatccctgca atatccgtaa
    10921 attcaaatgt tgtgggaact gtctttttag gagttatcat ttcagttagt ttttgtaggc
    10981 gttcatctgg aacttccacc attccaacat ttggatcaat agtcgcaaat gggtagtttg
    11041 ctgcctctgc tcctgctttt gtaattgcat taaatagtgt tgatttacca acgtttggca
    11101 aaccaacgat acctgctgtc aaagccatat ttctcattct ccgttttcat ttcaatccct
    11161 aatattataa cacaaaaagg gaaaacttgc taaaattcct tgatatagct atttcccata
    11221 actgaaataa taattttatg gactttttta ggaacttttt aatttttcaa tggctttttc
    11281 ataaaatgaa gtagcatttt tctgattgtc tttggatagg tggctataaa tatccatggt
    11341 catagaaagt tttgcatgac cgagccgtgt ttgtatctct ttgtaaggta gtccagcatt
    11401 gagcaagata ctagcatgag tgtggcggaa ggcgtggaac gtaaaacgag ggcatccagc
    11461 acgttccaaa tgttttacta acctgaaact aagcattcta gcgtctatat gcttatcaaa
    11521 gctattagag aatactttct cataggtcaa ccccatttct ttccctattt gggattgtct
    11581 tgctttatag agccgtagca tgagcaccgt cttattatcc aagtcaatta ccctaatact
    11641 tgatttagtc ttagggacag tgatttcttt gataatattt aacgttttat ttacgtctag
    11701 tgtgccgttt tttaggtcaa tatcagacca tttgagggct aaacactcac gaatacgcaa
    11761 accagtcgct aaaagcgtct tatatagcac cgtatcgtag aaatttttgt aagtgtttgg
    11821 cagctgctcc aggtaagtca agaatttttt taagttatca tcatccagat atttcagttt
    11881 ttgcccttct ttttccttac gacgtggcac gataacatca cgggcagggt taaaggggat
    11941 agcttgcaaa gatacggcat atttaagtat gcgtttgttt agagagtgaa ggagcggata
    12001 ttcttggaat cctttgccta gttgattata gtcttttgcc cattgattga cttgcttttg
    12061 aatgattggg ggcgtcagtt tatccagcct ataatttccg aaagctggaa gtagatattt
    12121 atctattttg aatttggtac ccattaaggt cgatttttta accgtatggc agtacgtttc
    12181 tagccaattc tccaccagtt cggcgtaagt ctttatctca actgctttat atactgtagc
    12241 ccctcctttt tcaaagtcta tttgagcctg tagtgctttg gctttgagtt ctctcttggt
    12301 tcgccctgat atagtcgtct tgactttctt acctgttacg gtatcgatac caaggtagac
    12361 gctagagcga tagactgtag aaccgtcttt tttggtgtat tctgttattt tcatggtttt
    12421 actccttttt ccatcagcag gcaagcaatt agaaaaggtt ttgagtttat accatgcgag
    12481 ggactgcgag aatgccccta ttttcgattt taattagcca ggcggtaaat aataccagaa
    12541 taggaaataa ggcggatatg ggatttgtat gggcgttttt acatatcatc aaagagtgaa
    12601 agttggttat tatccggttg ctttttaagt ttcttttgtt tgttttttag gtcttggcaa
    12661 ccacactttt ttcggagtct tcacataaat gttggaaaaa gtcggatttt caagaatact
    12721 ggaaaaaaac aattttcttc attttctgag tccctaaaaa gcgatggggt aaacaattcc
    12781 aatcccgttt ctattagttc ttaatggttg gaaaactaac atttctaaca ccctaaaaag
    12841 gagaagggtt tagacaaggt cagaggactt gctgaagccc gagaaagcac gcgcttcagg
    12901 attgttgaac attgtggcgc gtggtaggct ataggtcgca ttttcggcac tttcggcagc
    12961 cctaaaagaa aaatagtagc gatgcgcttc atgtttgttg caattttgcc caattttacg
    13021 ctttagtctg taaatcggct ttctattctt caattttccc cgtttttgca caatagacca
    13081 tgaaaaaagg gggtattcga tgaggtggta tatttttgtt tatgaattat gggtaataac
    13141 atctaaagct ccaataatct tttgagcatt ttcaatagct tctttgtatt ctttagatgt
    13201 gtttttaaca ggttttttaa ttaaatctat aaaaacaact ggtttagtaa aatcgttaga
    13261 tgttattcgg attgtcatat tcaaaatctt ggtagttgct tttcttttag cgacgattcc
    13321 gccagctacg gctcctatta caccaaatac cgccccagct actaaagctt gtccaacacc
    13381 gccggaaaca acagactgat cgtttataac taattcgtaa gatactaaat catcgaagga
    13441 gtaccagtcg gtatcatttt tatctttttt aattaaagat ggaatcaaag acaaaccgcc
    13501 tgtcccaagc gctaaggtag tttttccaac aactttagca gttccgccaa tcagacctga
    13561 tgaacctttt gcttttcttg ctccgtgtat tctatatgta cgatgatttt tgtctatttc
    13621 aagaggtccg actttatcag tacgtttact tcttacagta gaaggtctag acgatggagt
    13681 tgctactttt tggggagttg ttttaagcga ggcattgatt gagtatccgc aattcggaca
    13741 aaacttgcaa ccgacaacag aatttccgca ttcaggacaa aatttcataa tttttttact
    13801 ccttttttac ttttctctat aaatgcccac gacttcgccg atggtgcgta tatcgttgct
    13861 ttcgtctagt tgaatatcag cacattcagg gttaaggctt tctaaatacc cttgacgcag
    13921 tttcttgacg tagttagcgc cgtctacttg gaagataccg atagtgttat agtcaacttg
    13981 aggtgtattc ttgataaata ggtagtcgcc attctttatc tttggctcca tggagttgcc
    14041 gacgacataa gcgatagcgt catagtcgtc tgggatttca tcagtataaa agcatttttc
    14101 tatgtttagg ttatcgtctt gggttatccc gtttccggcg gttacaactc cgataacagg
    14161 gagcgtcttg ctttctctgt agtcgtccag actgataatg ttttctgata ctatgttttc
    14221 gtttttctgc tccagcagct gctttttaag ataagtcaag gctttttctt gtcttggtgg
    14281 agtgagttgg tcatagatgg attggatggg ggaagtggta ggtgtttctg cgtttttatt
    14341 ttctactaag tcagactttg aaacgttgaa aaaattagcc agcatttcga ttttatctat
    14401 acgtgggtaa gttttagcat ttacccaatc gttgacggtt gtatacttaa aatctaatgc
    14461 aatagctaat tgacgagggt ttaaaccttt tgcacttaaa agtcttttga tattgtccgc
    14521 cattatttgc ttatttccta atgacatggt gcaaccgcct ttctataatt cataatttaa
    14581 ttatacggtt aaaacgtaga aaaagcaagg gaaacaaaaa aaaagaaaat aaaatcaaaa
    14641 aaagtgttga caagttatcg gttttaccgt atactgtcat tgtatccgat ttaaacggat
    14701 atccaaaaga aaggagtgag ggctatttgc gtcttacatt gaaagcgttg cgggctaata
    14761 gcaacatgaa acaatcagag gtagcacaaa aattaggaat ttctacaact acttggagta
    14821 agtgggaaaa tggaaaaagt tttcctgatg ttgcccaagt aaaagagatt gaaaaacttt
    14881 tcggtgttgc ttatgacgac attatttttt taagctaata tccgatttaa acggatatag
    14941 aaaggagcga cccaatcgca atactatatt acatctacaa gatactccac tggtgcttta
    15001 ccactgggga ttgaccttct cggaagaaat atccgaccta gaacataaag gagaaaacaa
    15061 catgaacaat aaacaagtat atcaagcaca aacaactgac cacggtatcg ctagagcatt
    15121 aggcgaagaa attcgtatga tcacagacgt tgaagaaaca acttacaatg gacacggtga
    15181 aatcattgtt gagtacacca gtgacgttgc attgacaaaa ctatttgacc gtattaaagc
    15241 actttacgaa aaaggcgaaa gctacgaaac aaaaccattt ttacatttta aagtattgga
    15301 agatgatatt gaaccaagcc caaatggagt ttttactgct aaagaggtgg cagagttttt
    15361 aggaatttga ttaacaataa ggagcaaacc aatggaacta gtctacatgg acggcaagaa
    15421 agagccgtat acactgagca gtattgtggc agagtgtgca gaagttaagc acagacattt
    15481 aaagattttg ctgaataagc acagagagga ctttgagagc ttcggaaagg tgcaatttaa
    15541 aatttcacct tcagagagtg ggcaaaatgt acgagattat attttgaacg agcaacaagc
    15601 tactttgtta atcacttact tacgaaatac agaaccagtt cgtaaattca aaatgaacct
    15661 ggtcaaagct ttctttgaaa tgcgtgagga gctttctaag tttcgtatgc agagggcgct
    15721 agaaaagcca aaaagaaaaa ccttgcatga cagtattgag aactgggaac aagcacccaa
    15781 gcacgcgcat agcactatga acaacctgct actaaaagca gtaaccgaca ggaacgctaa
    15841 gcagttaagg gaagaacgtg gaggctataa tggcatcgat agcttgacca gtgacgagct
    15901 ggagcaatat caagcctttg aagacatggt aatagccatg attggcttga atatgagtta
    15961 tcaggaaatc aaggctatgg cattcagaaa taaaaaaaca cgccaaagaa gcgcgtgatt
    16021 gcaacaaaaa aggcttagca ataaccacac cgcaaagcct ttcacactaa gactaaaacg
    16081 aatttaacaa aaagcaggca agctattatt aaagaggttt tagtaagatt tatacctaga
    16141 ttatagcata atacagcggt ttccgctagt acattgaaaa taaaataagg tacgctggga
    16201 agattttaat ttttttcggt ttaggggttg acatttaaga cgacaagaat tataataatt
    16261 tatgtcgtca agaaaggagg caatccgatg actgacaaaa taaagaaagt aggacgtccg
    16321 aagggagaaa actctaatac cgtaaaatta acagtcagag ttagcgaaca gctaaatagt
    16381 aagctggaag agtacggtaa aaagaatggt ttgacaaaac ctgaaacctt gagaaaagcc
    16441 tttgaaaatc ttactaaata aaaaatacct tgcaacttgt caaacgccaa tccgagaagt
    16501 tgcaaagtat ccgcccccac gaatgaggta cgtaaatatc ttatcatgcg tactcttatt
    16561 tgtcaaacat agaaatagag tgcgcttttt gcgtacccaa aaatgaggta aagaatggga
    16621 aaacaagtat ttacacaaga aatactaaga aacatacaag aagaaaatgg aatcatcaca
    16681 gtagacttaa tactagacgc tttaccaact tggtcagaaa aagccatcaa gggacgttta
    16741 tcaaattggc gttaccgtaa agttattgac tacagggtag aagatgggga atttagtgag
    16801 attttcctac taagaagcaa gcaggagata aaagaagagg tcagtgccgg tcaacgtttg
    16861 aaaatggatt tatattttag acaggtttta gccttaactg gaatcattga atcaaacacc
    16921 agcaaggaca acgacaagac caaggcgatt gaattgcaac agaaagcaat gagagcaata
    16981 ccagacgaca tttacaaaga gttgtcagag atttatgagt aaataacaaa actaagaaaa
    17041 actaagaaaa ccgaagtgca ggcaagcaat tagaaaaggt tttgaaaagc atagagcgcc
    17101 aactctttaa actggtactt tctcacgctt tcaatttggc gagtctgagc gtgaggctag
    17161 tacttacaag aaaaaaactg tataagtaaa aagccccacg ctcagaagtt tggcgaccga
    17221 gagcgtgagg catgtggcaa gaaaaactgt ataagaaaca accattcaaa atccccacac
    17281 tcgccatcgc tcaactttga gtgtgaggat atcctggata gtaaaaggca ttaaaaagcc
    17341 cttagggcaa ctacacaaca tagaaacaga ggtacaagta tggaagaaac aacatacgat
    17401 attatcgcta aaagcttgga tagaattagt atggaattac accaagctga cgaaaataac
    17461 gattttctag aatatgggtt ttatcaggac aattaaaagg ccaacggagg aaaatatgat
    17521 agcagatcaa ttaaaagcta tttcaacaaa tttagaagaa atacaagaaa ttcttgtagg
    17581 agatggaact gcattagcta aaagagaaat cagcagggta ttgaacgact tggacgatgt
    17641 ttataatgaa ctaactagca cagaataccg tgaacaacag gaaacactta aggaacagac
    17701 ggaaaggatg aaacagagag tagttgctga agtaatagga ggactagaag aacgagaaga
    17761 gtcttattac agaaattatt ggggtgatac taagtttata aagctacttt ccaactttga
    17821 tggatttctt ttcttaaaca cttacctagc tgaaataact aaagaaaata cctacccaat
    17881 ggaacaaagt caattattga attatgtttg ggaagtcata gcggttgata tcgcaaagaa
    17941 aaaacgagga aaaaagaacg ttttggattc atggacagat tcatccttat atactcgtgg
    18001 aatgatgatt gattaggagg caatgcaatg acactagacc taggcaaaat gacacaagca
    18061 gaatttgatg aagtaatggc tgacatcaag gcaagaaatc caaacctatt acagttcatc
    18121 actgattttt tagatagaaa ggtaacaccc ggagaggtgg acgactagtt gaatatggag
    18181 cgagctgaac aagtggaata tattaagaat tatcaagcga gggcataaca tgaatgaact
    18241 agatataagt aacacacagg ctgctgtctt aatcgtgatt ttgattggtt tactgcttta
    18301 tttaaaccac cgagaccgca aaaaaagcgc ccaaattgag cgagaaaacc aacagacgat
    18361 aaaaacacct agcgaggatt taaaccctga atatgggcga tatatccagc ttgcaggagt
    18421 caacgtatgg ggagggatgg aatgagttac atagtgaaga tataccttga tagtgaaaaa
    18481 ataccagatg aaccttattt tactaaagag atttttctag ctacgtgtat gggcaatgca
    18541 acaaagttag ctgtaactat gggcttgttg acaaaacaag tgttggattt agaaactaag
    18601 acagctatct tgaaagccct tgatacaatc atagagactc aaaaagctat tttgcaaggg
    18661 gtagcgagcg gacaaataac ctttgtaaat aaaagtaaaa gagaggagga actggatgag
    18721 cctatcagag aacgataaac gagtattaag attaatcaag gtaggggctg agaactccat
    18781 aacagggtca gaaattagcc tgacaaccaa gctaacagaa agaactgtac gtgacattat
    18841 caagcgtcta gtagttaagc acaacatccc tattgtaggg gttagatgtg gcgtttttag
    18901 tgggtacttt attccagcga ataaaggcga gttactagat ggcgctaagg ctttttacaa
    18961 ccaagtacag gaggagagca agcgcctagc ggtgttgatg aatagcgacc tagaaagcta
    19021 caaagaaacc ttgaaggagg tgggcggata tgtttagcct aagccgagaa agcgagcaag
    19081 acctagcgca tggcattctg gaggtagtgg aaagatacct ggaagcgcgt gagaaagtac
    19141 cgccaagatt gaccaagtta ataaatagta gttgaactca aagaggaatt gaaaattagt
    19201 gacaacacgc tgaataagtg ggaaagtcag ggtttaagac gctatcaacc gccggacgat
    19261 ggttcaagaa tgatttacta tttagtaact gacatctgga agtttctggg ggtggatgaa
    19321 tgacaattta cgaggctaga ggtttccaga gtaatcttgt ctatccattt gataagattg
    19381 agccgttcca gtacattgaa cgctttaagc ctttggtagt ccctgaaagt gctgatacgg
    19441 aggaatacaa aagaacccag gcgccatatt gtttaagtgg taaggttatg ccggagaaaa
    19501 acgggagtta caaacgaaac aactccagtc taatctatcg ggatttgatt ttccttgatt
    19561 atgacgatat acaggggacg actgaggact tcatagaagc cgtttctagc gctttgtttg
    19621 gctactctta tatcttatac ccgactatca aacatagcat agaaaagccc cgttttcgcc
    19681 ttgtggtgaa atctaacaac gtgatgaacg aggcaaccta taagcaggta gtaaaagaga
    19741 ttgctgacaa gattgggcta ccctttgaca tggccagttt aacctggtca caactccaag
    19801 ggctaccagt aacaacaggc gacccagcaa cttatcaaaa gattgtagag catggacttg
    19861 attatccagt ccccaaggtt gaaccaagag cgaagcaagg aactactgag cgttataaac
    19921 ctagagtaag tggccagagg tcaatgacta tgaggattat tgacacgctt ttcaacggat
    19981 ttggagacga aggagggcgc aacgtagcgc tgacacgctt tgtgggatta ctcttcaata
    20041 agtgggttga ttgtgaccta gagacagctt atgaactgac aaagatagcc aatagcgtga
    20101 cggttgaacc attgcctatt gaggagctag accgtacttt tagcagtatt gcacgggctg
    20161 aatatagaaa gagaggttag aaccatagaa ctagaagaat tagcaaacct aaaaagtgaa
    20221 atcttggagg tcagagagca agaacaacct cctagaacga tgtgggaact ttatagtagg
    20281 atttgggagc ttggggatca atggcgtaag gaaaactcct atatcgtcaa tgaaggaaag
    20341 aaaaacgaaa gggtagaaat cccacgacca agtgttgcaa tcgtagccaa agcgttacag
    20401 gaaatttgcc attttacctt tataggtgag ggggttataa gtgatattag taagttatat
    20461 ctttaccatt tggatttagg ccattatgta tcaagtaacg acattttccg aaaattgctt
    20521 ttaaaatatg actcacgttt gacttctaac aagttctttt tagaacttat ctcctatatc
    20581 cgtacagaaa ctaagatgaa accaccgctg gacgattatc gatatattcc agtagctaat
    20641 ggagtttata atattaaaac tcataaacta gaggaattta gtcctaattt tgtcattacc
    20701 agtaagatac aaacggaata caaaccatgc gccagaaagc ctattttaga tggttggttt
    20761 gattttgata gatggttaga ggctttagca gttaacgata aagaagttgt agctttattg
    20821 tggcaagtca taaatgaggc tatcaatccc aaccgaacac gtaagaaaat ggtgctaatg
    20881 gttggagatg gtaataatgg aaagggtact ttccaatcct tgctggaaaa tttaatagga
    20941 cggtcaaata ttagtaattt gaaacctgac cagtttggga aagagttcta tttaggcgct
    21001 ttggaaggaa aggtttgtaa tattggagat gatatttcta acaagtacct ggatgaagtt
    21061 tctgacctta tgagtgtaat tagtggagat ccagtgcagg tcaataaaaa aagcttgcaa
    21121 cccgtggaag cacgtttcag actattgtgt atcttttcgg gtaatgattt gcctagagct
    21181 agaaataaga ccatggggtg gtatagacgg ctttgtatca ttcctttccg tgcagatttt
    21241 aacggtcaga aagaacgtca tgaaatcaaa gaccgattta taaagaacaa agagctgcta
    21301 gagtgggttt tgtttaaagt tttaaatatg ccagattttg atagctttat agaacctgaa
    21361 gcggtacaaa aaatgcttag caagtacaaa aacgataacg attatatcaa agtttgggta
    21421 gagaatttct acataccaaa cgggtggcat gaaataaacc atgttccaat gtttattgca
    21481 agaaataaat taaaagagtt tgctgaggat ataggtatag ataaacctaa acttggacaa
    21541 tttagcaatg cagtaatggc cgaattggaa aaaacaacgt catataagta ctcagccaaa
    21601 aacggaacgg ttagctctaa gttttatgac gtacttgacc cacaaggttt tcaacgtaaa
    21661 agatttgtta aaggtatatg gggaatacac ttagaagatg aagatttagg ttaggaaatt
    21721 taatactaaa aaaccaatta caccaagggt tatagcaatt taggttatgc aaaaaataga
    21781 aacataacct aaacactaac ctttgtaaac gttgatataa aagtctttgc gagtatttag
    21841 gttagtaggt tagtttttat ttctaatatc tctatataaa aaataatata tatacgtgtt
    21901 atataggcgc gaacttaaaa agtaaaacta accctaatct aacacccttg aaacgttgat
    21961 atagtaggct tttgaagggt tattttttaa aactaatcaa aacctaatct aagagaataa
    22021 aggagcaaaa cagatggcga tgaacatttt gtcaaagagt ggctaaccgt tgagcggatc
    22081 agtgaggcgc tggatggctt tattgagaat gcgaaccata acgctatagt aagcaataaa
    22141 aaacatcgaa cggattcagg aaggttttga aatagtcttt aaagagcttg atgaactaaa
    22201 agcagtacct gacaaacact aaaacattta aacaaaatgg ggtagatagt accgaccccc
    22261 ttgcaatggt gtaactacta gtgacaccct aaaaacagaa agaggaaaaa caacatgaca
    22321 ttaaaaacat tttcagataa agcaaaaaca tttaatttca cttacgaatt taaagaccaa
    22381 gacaccgccc aagtggcagg gagtgcattg atgggctaca tgattggaac ttatgtagta
    22441 ccgtctattt caatcactta caagaataaa gggacgctag tagctgagta cgtggaggat
    22501 cacaagctaa acaagacctt caaacgtatc tgtgacggtt tcaaagacta ttacaagcaa
    22561 ccagagggag atgaagcatt tgaagaacgt tataaacggg agcgcgtgct tcaactcaaa
    22621 gagtcagagg actttgagag cttgctgaat aaggtcacag actacgagct gaaactatta
    22681 gactatgctg aacgcttgct ttctgataag cctatcctta tgaactctat gactgctttt
    22741 ggtacgttgg aagtgctggg taatgaaagt attaacctat tccaaaaatt ggacgtagag
    22801 ggcgaatata aaggccttgc tgattattct ggtcaataaa cacaggggag caatcccctt
    22861 tttttacata aatcagacag aattacacac gaggtagggg gatggttaga agtttaaaag
    22921 caagactaga aaagttagaa gagtatgctg gaaagacgga atatgcaaca actgatgaat
    22981 gtatatcttt atatgtggat tgtttaagat ttgcttttca gcaagatgaa ataaagatag
    23041 atatggatga ttttattaaa acaccattta aagatattaa gctagcagac tataagaaat
    23101 caaaaaaacg tatggatgaa cttagggaaa tgactgggat aagtgagttt tcagaattag
    23161 agcaataaag cgaggtgaac agtatttgac agaattaagc agaaaaaaag aaatatttat
    23221 ggccaattat ctcatgactg ggaatgtaaa aaaagctagt gaattaagtg agatcaccag
    23281 aaagacggct tacaattact tgaacgatgc aacctttaag agaatttacc gtgaaagacg
    23341 tagcgaacaa cttaaggagt ctactacgct gttacagaat gcaagcgttg aggcagtcaa
    23401 tgtattaagg gaaatcatgc ttgataagac agtgagcccg tatgcgagac aacaaagcgc
    23461 ccaaagcatt ctaaacatgg cttataaggc ggttgaaatg gttgaggtag tggagcaatt
    23521 agaaatatta gaggcgaaga tactagatga aggcgattaa aaaccgttta aataagttga
    23581 ataagttagc ggtggttgat gaagttgata ccgtgttttt gacgcagatt gatactggac
    23641 attttgaggt aagatatagg ataggtggaa aaaatcccaa agatattata gaagtctatc
    23701 cgacaaaaga agaagcagaa aaagctattt cagaaattaa aaatacaaaa ggattgcgga
    23761 tattctggga caatttggct ttattggagg ataattagag cttatcattt atcaagcaga
    23821 taagagaaat aataaccctc cttaactcct tgagaaacga caagcagata agcgaagttt
    23881 ttagccctct tatttcggtt ctactccttg cagaatgaca aggaaataag agagataaaa
    23941 acatccctta attgcttatc aaaccacaag gagatacggg ggctatctcc ctccccacgc
    24001 acttctatga gcttcacacc gtcattgtac attttttctc acggggaagc atttgaagct
    24061 agagcgaaca tagagaaaac gaaaaaagcc aagacactct ctgtctcagc aataatctca
    24121 ataatattat tatatcacaa aggaggccga gacatgacac cagagcaggt aaaagaaaaa
    24181 ctagagggcg ttaagtggat aaacaaattt aaaagtgtgt agattacaat ctaacacaag
    24241 aaaagaaaac gcccttttgg ttgttcttta attgcttcat caactatctg agatgtttga
    24301 taagaatatt tcattgaccg tctccaatta cacataggac acaatttatt cttacaaaaa
    24361 taggcttgat ataaacgcaa actcccatct tctcgacgaa taaatcgaag agtatctcca
    24421 caagtctcaa cgcgttctat caaggtttcc ctataaccta actctttaaa aatatctgcc
    24481 aatttcaaac ttaataattt tcgtcctcgc cagtttctat ccttgcctct tttattttta
    24541 tctaaaagaa ttttatcttg attttcccac ttctccatgt tataatttac ctgtaattac
    24601 aaagaaatac aaaaatacct ttgccttttt tctcttttta taattttttc tgaacaacta
    24661 aattataaaa gatccgttga aaaaagtcaa gggcattttt ttacctaaaa agtcagtagt
    24721 atcaagggtt tagaccctgt cgaaacccta aaaatagcat gagagttatt tcctactagt
    24781 atcaagataa gaaaaaacct actcttcgag taggtttttt acggagcttt cagctccttt
    24841 tatatatcta attaccgttt ttaccgtttt cctctatatg gaaatacaat gaataaaaac
    24901 aaaactaatg ctattgttaa cagtattttc atcggaatag ggagattatc tagccatatt
    24961 tgaatagaac caaaaagctt tatatctaaa actttatcaa aaaactttat aaaaaaatat
    25021 aagactatga cactccaaaa taaccaagct ttattcataa caaactcctt gttatttaaa
    25081 ggcagaatta aaatcgttta ctgatcaact tacactcctc tctaaataaa ttaaacaatc
    25141 ttattctcaa tataataata catttttata aacaaaaaaa caagtctata tttcggtttg
    25201 ccgataactt ttttatatca tacccgcttg ttttattcca tggtctactt gaccgcaagt
    25261 aacctaggtc gacgtacttt gtccgtgccg ctccgaaacg ctacagcctt tcggctcgtc
    25321 cctgactagc gtactttgat ctagcttacg gtcaagtagc tttcacggca taaatcgctc
    25381 agaaattaca atatactttc tactaaaaat accccaaaaa tactaccttg atacaatctg
    25441 aaactacatt tttcagtcga gtattttcgt ttctaaaaaa agataaatct ctttttaggc
    25501 tctccatttc gtttttaagc tcatctttgg tttcctgtaa ttctaagggt tttatcctct
    25561 aaaaaatcaa ttctggagct cctgacggct attaattcat ctattctctt taattcctct
    25621 tttgcttgat taacattttc cataatctct ttatactcgt tcatatcttt tatactattt
    25681 attccaacaa ccttacaaga aatattaagt tcctttaatt ttagtccgat tttttaaaaa
    25741 gaattactac aaattgatac taaaaaggta caaaaaaggg gggtaatcgt cgaggtaaag
    25801 gggggtaatc gtcgaggtcg cgaatttgta aacccttgat attactgact ttctaagggg
    25861 tcaaaatttt caatactatt aaaactatta agactattaa agagcacccc ccactctttt
    25921 aagaagtggg ggtatgctat aataaaacca gtaaaaagaa aaggcgggag cggacatcac
    25981 tttttcttta gaggcactca agagaggtaa gcatggtaac agacattgaa caagcaagaa
    26041 agaactatat ggcagactat acgccagtag accttacaga cgcacacaaa ctactagaac
    26101 tagctgaaaa gctacaaaac gaggatataa gtatcaacac ttacgagtta tacaaacatc
    26161 cagaagcaag agagaaatta ttttggcagg ttgctgaaga aatagatagg tcaaagacta
    26221 cagtatacct tataaggcaa aaagccatag aacacttagc aaatgtgggg taataggtga
    26281 gcacaaaaaa acgcctagaa caatctaagc gctaaagagt agtggacggt gtgcctgtcc
    26341 cgtcatctca tactatgaag ttgcgtagcg acactatcat ctctacctca cttctcttta
    26401 aactaattat accacaaagg agcgaactaa tggagctgga taagtttaaa acgatgatga
    26461 acgtcagaga gcggatgaca tgattgaaga ttttttgatt gatttggaga atatccaatt
    26521 agaggacatg gagatagatt ttaacatgga gatagacatc gatttaaaca tagattttga
    26581 aatagatgtt gaccttgatg gtttagattt gaccttacta caagaattag aagcgtaaat
    26641 gttggtaaat gtaggctgag gcttcatatt cgcctcccta tttcgcttgg tttcgtaccg
    26701 gacgattaaa acaccatgga taaactagaa gcccttagaa acgaatcagg gggacttttg
    26761 tgaggtcata atcttataaa ccacgcgctt catggtataa tatacctatc agcaaccagc
    26821 aataaaaaaa gcacgtttga acgtgctagt ttcttgcctg ctgaactcat cgatttagta
    26881 gcccttttgt gggctttttt tgtggacttt ttgagaattt ttaagaactt ttaatgattt
    26941 ctaatcaaat gagatttttc aaaaagtcag taatatcaag ggtttaggcg ctataaacaa
    27001 atttaaaagt gtgtagatta caatctaaca caaaaaggga taaagtgcta accctctaac
    27061 taagggttct cagtcaataa ttttattcat ttttcgctca aaatcatatc gccccatcat
    27121 gacaacatgc tcacaattac tgcattttat tttgatatct gctcctacac gtgtaatttc
    27181 ccaacgatta gcctttttac cagtcgactt gattgtacaa gcgtgtgatt ttttcatctc
    27241 aacaaaattt ccaacttgat acatactact ctccttttct ttttcgatta tatcataaaa
    27301 gaggcgagcc aggctcaacc tctttcactt aatttgtacg aactggtgta atgagctgca
    27361 tgaagtcttc gtcagtatct gctggcacaa gagtaaatgg acgaacagct gagataaagc
    27421 taatggtcac cttttcgcta tttaaagctt taagagaatc aatcaagtaa gttgggttga
    27481 aactaatggt caaatcttca ccagtaacct gatcagtatc gatttcttcg tttactttac
    27541 caacttctgg agagtgaaca tgggcgctaa caaccccatc cttaatttca agtttcacag
    27601 taccattttg agtcgcactt gataaaagac gggcacgctc cattgactgg cgtaagttta
    27661 ccacattaaa agtaatagta gtgttaaagt ctgttggaat caagcgatct gtatcaggat
    27721 agtttccttc taggagacga gtatagaagc taatattttc gcttctaaag aggatttggt
    27781 tattggcaaa gaaaatctct acagtttcga tatcatctgt aaataccgct gaaaattcgc
    27841 gtagagaacg gctaggaatt acgacatcaa aatcatcact atttttttca agagtcaatt
    27901 ttttctggct taggcgatga gagtctgttg caactgtttt taactctttg tgttgactca
    27961 atacgaagtg gacacctgtt aaaatcggac gactctcttg tgtacttgca gcaaaggctg
    28021 tttcattaat aattttcttg agtaattttg tttcaagtat taaaggagtg cttgctgaaa
    28081 tttcttggat tcgtggatat tgttcgctat cttttccttt tagggtaatt tctgatttgc
    28141 cactggttaa aacaatttga ttttgttcaa tttctttaaa atcaagagtt acatcaggta
    28201 aactagatac tacattgata aagaaagaag cttcaagaag gatcgaacct aaagaagtaa
    28261 ttaacaaacc agcatcttca tttttttgag aaataaaatt ttcaattgaa atttgaccat
    28321 ttgaaccaat taaagtaata ccttcattgg tcacgtcaat ttttactgtt gataaaatag
    28381 gaatggcatt tttagaacta
//
LOCUS       DAVLDI010000025        28386 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLDI010000025 DAVLDI010000000
VERSION     DAVLDI010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28386
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.025"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..757)
                     /locus_tag="VXD01_001113"
     CDS             complement(<1..757)
                     /locus_tag="VXD01_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001857891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601530.1"
                     /translation="MGEIGIILLLISTIFCVSPVFIKLDILGTPSHAILTFVLAIPLF
                     YILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFSPGVAVFY
                     KESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQKLYRIEN
                     QQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIKPYLSESV
                     REQIDLLEVKRFKKINHPISLYGMLDVIKLNLYL"
     gene            complement(939..1997)
                     /locus_tag="VXD01_001114"
     CDS             complement(939..1997)
                     /locus_tag="VXD01_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601531.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTYRILPFSVFTFMFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            complement(2878..3090)
                     /locus_tag="VXD01_001115"
     CDS             complement(2878..3090)
                     /locus_tag="VXD01_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601532.1"
                     /translation="MLIVLISVIVALLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIEISGANLLLSFLKKLQIK"
     gene            complement(3098..3469)
                     /locus_tag="VXD01_001116"
     CDS             complement(3098..3469)
                     /locus_tag="VXD01_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HEV0601533.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
     gene            4106..4969
                     /locus_tag="VXD01_001117"
     CDS             4106..4969
                     /locus_tag="VXD01_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0601534.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKIHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(5155..5625)
                     /locus_tag="VXD01_001118"
                     /pseudo
     CDS             complement(5155..5625)
                     /locus_tag="VXD01_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
     gene            complement(5591..6397)
                     /locus_tag="VXD01_001119"
     CDS             complement(5591..6397)
                     /locus_tag="VXD01_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV0601535.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(6604..7245)
                     /locus_tag="VXD01_001120"
     CDS             complement(6604..7245)
                     /locus_tag="VXD01_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601536.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(7242..9350)
                     /locus_tag="VXD01_001121"
     CDS             complement(7242..9350)
                     /locus_tag="VXD01_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0601537.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATVLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(9402..9689)
                     /locus_tag="VXD01_001122"
     CDS             complement(9402..9689)
                     /locus_tag="VXD01_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0601538.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTVMEYFYGFE"
     gene            10120..10440
                     /locus_tag="VXD01_001123"
     CDS             10120..10440
                     /locus_tag="VXD01_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0601539.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(10493..11065)
                     /locus_tag="VXD01_001124"
     CDS             complement(10493..11065)
                     /locus_tag="VXD01_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0601540.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            11307..11978
                     /gene="sdaAB"
                     /locus_tag="VXD01_001125"
     CDS             11307..11978
                     /gene="sdaAB"
                     /locus_tag="VXD01_001125"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV0601541.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            11987..12859
                     /gene="sdaAA"
                     /locus_tag="VXD01_001126"
     CDS             11987..12859
                     /gene="sdaAA"
                     /locus_tag="VXD01_001126"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV0601542.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            12881..13513
                     /locus_tag="VXD01_001127"
     CDS             12881..13513
                     /locus_tag="VXD01_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0601543.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            13563..13640
                     /locus_tag="VXD01_001128"
                     /pseudo
     CDS             13563..13640
                     /locus_tag="VXD01_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(13906..15756)
                     /locus_tag="VXD01_001129"
     CDS             complement(13906..15756)
                     /locus_tag="VXD01_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV0601544.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(15798..16955)
                     /locus_tag="VXD01_001130"
     CDS             complement(15798..16955)
                     /locus_tag="VXD01_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0601545.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            17013..18179
                     /locus_tag="VXD01_001131"
     CDS             17013..18179
                     /locus_tag="VXD01_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV0601546.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTMALFTVDRADKIL"
     gene            18318..18644
                     /locus_tag="VXD01_001132"
     CDS             18318..18644
                     /locus_tag="VXD01_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV0601547.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            18631..19224
                     /locus_tag="VXD01_001133"
     CDS             18631..19224
                     /locus_tag="VXD01_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV0601548.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            19217..20128
                     /locus_tag="VXD01_001134"
     CDS             19217..20128
                     /locus_tag="VXD01_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV0601549.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKENQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            20190..21254
                     /locus_tag="VXD01_001135"
     CDS             20190..21254
                     /locus_tag="VXD01_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601550.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(21325..22171)
                     /locus_tag="VXD01_001136"
                     /pseudo
     CDS             complement(21325..22171)
                     /locus_tag="VXD01_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
     gene            complement(22446..23432)
                     /locus_tag="VXD01_001137"
     CDS             complement(22446..23432)
                     /locus_tag="VXD01_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV0601551.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(23704..25179)
                     /locus_tag="VXD01_001138"
     CDS             complement(23704..25179)
                     /locus_tag="VXD01_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV0601552.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(25437..26360)
                     /locus_tag="VXD01_001139"
     CDS             complement(25437..26360)
                     /locus_tag="VXD01_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0601553.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(26374..27303)
                     /locus_tag="VXD01_001140"
     CDS             complement(26374..27303)
                     /locus_tag="VXD01_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0601554.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(27622..27843)
                     /locus_tag="VXD01_001141"
     CDS             complement(27622..27843)
                     /locus_tag="VXD01_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601555.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQEELQKAVLF
                     LADEKGSEHTEAELIDNLKEVIAKLKANA"
     gene            complement(27797..28057)
                     /locus_tag="VXD01_001142"
     CDS             complement(27797..28057)
                     /locus_tag="VXD01_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601556.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT         8871 a         5963 c         4911 g         8641 t
ORIGIN      
        1 gtaaatatag atttaatttt ataacatcca acataccata aagtgatatt ggatgattta
       61 tttttttaaa tcgcttaact tctaataaat caatttgttc acgcacactc tctgaaagat
      121 atggcttgat taaactgata taagataaag ccacgcatgg caactcagat tttgattgca
      181 atttccaaat ttcatgataa tcctgaagat taaactcaca attcttctta gattccagta
      241 ttgttagtac ctttgatttt aacagaaata attgctgatt ctcaattcta taaagttttt
      301 gtactaatgc tatgataata gaaaatggaa taagaggcaa aagcaacggt ttgtcataca
      361 caaaagtaaa gaaaaaatag tatgaaatta gtgttgtaaa gtacaagaag tagtaaaatt
      421 taaacagatt cttagttgtt tgactctcct tataaaacac tgctactcct ggactaaatc
      481 ccattagttg gtgaaagaga attcgatagt atttcctagc tcctataatg atcacaaata
      541 taaaataaaa ataaattggt cttaatttac aaaagattga ggaaactagt aatagcaaag
      601 tatgtaagca ttgagacaaa atatagaata acggtatcgc caatacaaag gttaagatgg
      661 catgagaggg agttcctaag atgtccaatt ttataaatac tgggctgaca caaaatatcg
      721 tgcttataag cagtaaaatt attccaatct cccccatcaa gatagcttat ttatcctaga
      781 caacgcctac tgcaacagta taaataagat tcatcagcca tcttttctgg caatcatatg
      841 ggtagactaa tgatatttct agttactcaa aaatatctag ctatactaga gttatttcta
      901 atccctagga cacttgttaa tccaaatgta acaaattttc accccttaat aggactcttt
      961 ctggaaaaaa tataaggtct atctttataa aaaaatctat catattggga tggcacgcat
     1021 ctggaattta aacaagctat aaattcattt ataactacta tttgtttaga ggcaacagca
     1081 tcttgtatac cgccctcgaa agaaccatct tgtaattccg aaatattttt gtttaaatat
     1141 tgttttgaca aatctcttaa tgcttcatta tcgtaaatga ttcccaaaaa tccaacctta
     1201 tatagtaaat aatttaaact tacaaagtaa ttgaatccca tagtatattt ttctttataa
     1261 agcaaaggta aaactttata aaaaatatct aagtcaacct cactctgatt ctgaagcaag
     1321 taggagtcaa gcaaattttc aaaaatagct aacaatatga ttggtgtaaa gtttttgtat
     1381 tcacatgtca agtattctga gtatcgtgca gatgatattt cttttatata actttttgaa
     1441 agcaagattt tttcaaattc atcatctatt attaatcttc tatttccaat ccaagcggta
     1501 ttaccaccca aataagattg tacaaatagc aatatataag aaaacatgaa cgtaaatact
     1561 gaaaaaggta gaattctata cgtaaaaaaa tagacgataa tggtagccag gagtaaagat
     1621 atctctcgtg acaatcgaat tcttttcagc atctttttta acagtccgta aggttgtcct
     1681 tggcaatatt cttgaactaa attaatcgga atgacatctc tcaccatttc tggaaagtag
     1741 agtaagttta taggttgaaa tctccagctc ccatcataag taaatggata tagaaccaaa
     1801 tacttaaaag atttttttct tataaactta attatcacaa tatgaatgac tgttgcaatg
     1861 aagtatatta aatataaaag taaaaccgcc atcaatatac ttacaaaaat ccccttggaa
     1921 tcaatcaatg gaaaataaaa tattgcaact agaagcgaat aaagtcccgc taataaatat
     1981 ttctgatcat ctttcattca aaacaccata ttatttacta agaatgcatc aatacaatag
     2041 agcaactctg taagtcaata tttgataaag caaagcttta accccttccc cagacgttag
     2101 cttttcttca acccactaca gttgacaagg agcccaaatt attgataaaa actttagtca
     2161 tcatcgtctc tataaaatat tttctataca ctcttgataa taccaaaatt aatgccaata
     2221 tcataccaag agctataata atagaattta ttagatttat tttagtatat ccaatcacta
     2281 gtccaataat tggactagca gacatgctta gatataataa aaataacaaa aaatgaattt
     2341 caccaattcc tgcaaaaaaa tgtttcatag ctatagtttt acgcccataa atacccatca
     2401 aatttaccgt ctacgatatc taaaccatat gcaatggctc ctcctaatga gaagacttca
     2461 gcaacagtag ccgcaatatt aagagcatta gtaatagttg ccatactaac tccaccaata
     2521 tatcttgtta taacacttag ttacctagat aagatatcct ttagcttgct tccaaaattt
     2581 aagtctgcac ctataatatg agttcatatt aatactgcta aatcctatct atagtaatgt
     2641 caaacaccca aataaagtca tctctccaat tcattcaaga aatgaagaaa ggcaaaaaat
     2701 ctttaaaata agaaaaatgc atattatcag gtgttcaaaa atattgatga tatacgttat
     2761 atagatagaa agatttactc aatctcattt tcaaattgag ttttttccca gcctcgtttt
     2821 taatttatat cttcaataga atctaatgac ctagttgata tgttatatgg aataatatta
     2881 tttaatctgt aattttttta aaaaacttaa tagtaaattt gctccactga tttctatcaa
     2941 tatttcaatt ggtaaaaaat agtaattcca aataaaatga gaaatcagca atgatagaaa
     3001 aataacaata tcaattttcc tgttgttgac atactctgta attttatgat acagtaatgc
     3061 aacaataact gaaattaaaa caatcaacat aagattatta acctattctc aattgattat
     3121 cacgtcgccc atcccagcca tcaataatat tggtaaaaat ccaatcagct ccagcaccaa
     3181 ttccagcaga tgcaatactt ctaataacag tatttgcaaa agcatttcca atatgaattc
     3241 ctaatactcc taaaccttta acaatcccag ctaccagtgc ggagcgtaat ccataagatg
     3301 caagaactag ttgaaggcct ccacctcctg ctgctgctaa tgctgcatat gctgcaccag
     3361 taatggctcc tgtaattgcc cacctgggta tatatatagc ccccccatca aggtacatca
     3421 tctcttcttc atcaatcaca acataattat ttggtaatac aagttccatt tattttctcc
     3481 ttttttatta agcatgctta ggatggtttc ctaacaagtg atcgcaggct ttgtttagtt
     3541 acctaaatta gacttccttc ctttatctta ttttaaatat ttaaaaccag ttactgcttg
     3601 aagcttaaca gtttacttaa ttcaaataac agctaatcac tgattccctg attttatcaa
     3661 atatactaat aacaacaatt gtgatacgat catcattata agaacaacat ttaacgaatc
     3721 aaagtttttc cgagataata ataaagcaac agcaagcagt attattacta aagattgaat
     3781 aactactatt actcttaaca ttttatcctc cactaacaac tcaagctccc ttacattata
     3841 tcgaccagcc ccatggaaag attatagcta gactaatcaa tgatataata catactagaa
     3901 tacaaaatat ttttttattc atactttttc tcctatcttt attttctacc tacatagtac
     3961 ctcttattaa gctcatttca aaattacgtt aacttttttc acaaatttat ttcgactttc
     4021 ttttttactt tttacattgc tatgatacaa tatttttaac aagattttat tatttgttaa
     4081 cttttttcac agaaaggaga aaatcatgcg ttatgatttc ggaaaggtct ataaagaaat
     4141 acgtgagtca aaggggctga cccaagaaga ggtctgtggg ggtgttctct caagaaccag
     4201 cttatcaaaa atcgaaagtg gcaagacaac cccaaaatat gaaaatatgg aatttcttct
     4261 ccgtcaaatc aatatgagtt ttgaagagtt tgaatatatc tgtcaacttt atcaaccaag
     4321 tcaacgcaca gagattatgc aaacctatct caatatgcgt tccattatcg ggaccagcga
     4381 tcttgtcaat ttatttcaaa aatgccaaga ctacctcaag atccaccacg atctccctat
     4441 agaagaaatc agagatatgc ttgaagttgt catttatatc cgtcaacacg gggcagggga
     4501 actatcagat cacgcagaac aggttgtcaa aaaactttgg agaaaaattg aaaaacaaga
     4561 tacatggtat gagagtgatc taaaaatcct caataccatt cttttcagtt ttcccattga
     4621 atacctccat ctcatcactg gaaaaatatt gcaacgccta gaagtctata aaaactatca
     4681 acatttatat gacttgcgaa tagcaatcct gctcaacctt tccacactct atctatacaa
     4741 tcaagataaa aacatgtgta agcaaatctg ctacacttta ctggaggacg ccaagaataa
     4801 gaaaagctac gataggctgg ctatctgcta tgtccgcatt gggatttgta cagacgattc
     4861 taaacttatc caaaaaggtt tctcactcct agagctgacc gaggaaactt ctatgctgtc
     4921 tcatctcaaa aaagaagtag agatctatta ccaagcgaag gaaagataaa aaagccgagg
     4981 gagctcctcg accttttcat agaatcgccg aacgatttaa cgagaaagta tgacttttac
     5041 gtttatccca actcaattat gacatttttt tcaaaagtca atatatctca ctttttcaac
     5101 gacaagaaag aggctgccaa tcgaccaacc tcttattctg aacccatcac tccatcactt
     5161 tttagcttca ttcgctttct tagcgactgc aatctggtat tcgacttggt caaacccctt
     5221 accggtacaa ccatgagcaa ttgtagtcgc tcctatctga tgcgctattt caaccaattt
     5281 tttagaaatc agagggcggc tcaaggcaga taccaaggga tacttttgtt cataataggc
     5341 atgtgactaa tgagccacta gcacataatc tgtagcaaat tcgtccttaa catcaatgac
     5401 ataagattct actgcccaaa ccttaagagc cttatcatgg atgaaatcta agtctttccc
     5461 ttcacccaca tccatacaaa ctgaaacaac atcatagtct ttctttaacc aggtaatagc
     5521 aactgatgtg tccaaaccgc cagaataggc caaaattact ttttctttac tcatgttctt
     5581 ttccttcttt ctatttttca atggatgctt taaaggcatc ctcaatgagt ttgtctaatt
     5641 ccccagactc cttcaacttt tgaatggttt tatcgactgc ctctttcaat tccttgctat
     5701 cttttttcat ggctaccgca taggaatcat cttgctcttt ttcaaaattg aggtctgcga
     5761 ttgctaaatc aggattattt tccacaaatc ccttggcaac gggttcttca aaaataacgg
     5821 catccacttg ccctgatttt aaatctgtga ttaaattccc atttttaggc agagatacga
     5881 gggaagaatt ttgtagcaaa tctttcgcca tcgtctcttg aatcgaacct ttctgcgctc
     5941 cgaccttttt ctgcgccaaa tcgttgacag actgataagt ggctaaatca gattttttga
     6001 caatgagttt attttttgca gtatagtagg gagttgaaaa atcaaacacc ttgctccgtt
     6061 catctgtctt agaaacacct gatatggcaa ggtcagcttt tcctgattga acgctagcca
     6121 gtacattgtc aaaactcata ggagatagtt ccaattcgac acctagttct gttgcgatag
     6181 ccttggctaa ttcgatatct gaacccacaa tctgattttt cccatcaacc actttttgat
     6241 attcaaatgg agcaaaatct ggattgaggg ctacaaccaa ttttcctttg gacttgatgg
     6301 cttcaattcc agccgattga ttgttactac aagcaaatag tagggggagc atcactaaac
     6361 caaacatcgt catcaacacc ttcttcatct tattcataac aaagcctcct ttatgtttat
     6421 tcttttttat tgtataaaca atactcctat actcatcctt tgtcaagcct aaattgaaaa
     6481 aattttcaat ttgaaacaaa aaaaacctag aaatactaca taaaatgtca ttcctaggcg
     6541 tatttatgct atttttctct ggaaaacatg agtattcagc cagtcaaaag gagctgaatg
     6601 aactcatttt ccctcgccca attcaatgac acgatgacat tgttgggcta cataagcatc
     6661 gtgggtcaca ataatgactg ttttcccttc tcgattcatc tctaagagaa acttcaagac
     6721 caaatctcta ttttcaggat ccagcgaacc tgtaggttca tcggctaaaa tcagctggct
     6781 gggttttaag atggctctag caactgcaat tcgttgttgt tcgcccccag acaactcgga
     6841 gaccctttga tgcaaagtag ctgacaaacc tactctctct aaaatctctt ccaccttttt
     6901 gagcttgtct ttcttaggca atttcacata tttcagcgcc agcatgagat tgtactcgac
     6961 cgtttcatca tcaatcaggg caaaattttg aaacagataa gagatatgtt cacggattat
     7021 tgtttgcgac ttagcagaat taaccgctag atttgtctga ccaaaaatct cataccgtcc
     7081 gctataatca ccatctatca aacccaataa atttaacaag gtcgacttcc cactaccact
     7141 cttaccaaca atagctacca aatccccctg atcaatcctg agagataagt tatccaaaat
     7201 cacttttccc ccaatggttt tggtaatatt tttcaactca atcataagat gccccctttc
     7261 aataactcta ctagacttct tttctccatc ctagaagcta agcctagcac aaatagtata
     7321 tccagacatg taaaacctgc aaacagtaga agtggtaaga acgcatgggc aaagaaaatc
     7381 aagactagaa gagggaaact atagcccagc aagagcagaa cgaggagagg acggtagcga
     7441 tcgaccagtt tccaccccat aaacttcttg gtaatgatat ccctgcgctt caataagaaa
     7501 gttgttacta gtaagaagta ggaaatcatc atgctaagga gaccaaacaa agcaaagagt
     7561 aggttaaaat tccgaacagc atctctataa gaatccactt tctcttgttg aatggcttga
     7621 atagatgaaa attttaaata atttccatct gacaatttct caactaactc tgtaatctct
     7681 ttttgatgtt gaaccgtatt ttcaatttta atcggattat ttaagccagt tgttgacagg
     7741 gaggctttct catcccacat catatcagaa tcattgacca agctaataat tggattggag
     7801 agattttcct ttcgcttatc actatatggg aaaaatgacc aatctccttc ataataggca
     7861 atctcgacat ccatctcctc tatcgttcgt ttttgctgct cttcatactt catcgaatga
     7921 aaggcaatta acttccccaa gagctgattt ttatcttctt cacctttcgt acttgctggc
     7981 atcaaaataa cttttttaat accggtatct ggtagcttga atcccttgct ctttagaaaa
     8041 ttgcgattgg catagtaaac atccaccgta tctgttaact gatattgctg aatctgttct
     8101 gattggacaa aattttttac aggaagactg ctactctgca catagcccgc ctgcgttttt
     8161 tctaccaaat cctgataaaa tcgatagaaa taatctgtag atttccctga ccctgctagc
     8221 tcttcttgcc acagattatc attgagtttg aaggtttcta aggtcaggta attaccttga
     8281 cttacccact gttgctgata agcaagttct ttgttttctt gttctaaact tctgcccacc
     8341 ccaatcagta aggccgtcag taaaatagtt gtccctattt tcatcacata attgaagata
     8401 agaccaaatt tgaaagatga aaaacctttc agcagagagc tgattgtcat tttttggatt
     8461 aagaggtaag tcaaccaact gataaagaga taaagctgca acagcaaaaa atgagacaac
     8521 cacagcatag gaaacaaatc ttttggctta taatcaagca agaaaaacac gcctagattg
     8581 atcacaagag ccccacctag gaggaggtaa aggttgcctt ttacaacatc agctaaaaca
     8641 gccctatctt gaaaaccaag taatttttgt accccaactc ttttcatctc catcatcggt
     8701 tgatatactg tcactaacac aagaagcaaa atagccaaga caaaaacaat ggcagataaa
     8761 agcaaatctc gatttatgac ttccactgca cttttgtagg tcggctctag cacggtagcc
     8821 tggtctatct tgaaaaaatc gctccatttc tgtacaatcc tatccttgtc catctcttgt
     8881 gtagaagtta tcgtatagcg accatttaaa ctacgagatg tatccttgat ataggtttga
     8941 aaagtcataa gctgaatagg tttggctttt agaaaggtcg gaatcgtacc aagtttattg
     9001 gaaatttctt tattactata gactccttca ccatctgtgg taaaatcaag agaagaaatc
     9061 ccaaactctt ggtaggggaa ggtatcttta tcaaaaacac cagacttgac cacctcatca
     9121 ccactgtctg ttttgatgat ggagacttta tactcctttg atacatcctc aaaaaatcga
     9181 agaacagacg ctgcaggttc gttaatatct ttcaaataca aatccaaaga atctacagtc
     9241 tttcccattt cttgaatccg aaccacttct cgtgtatagt ttacattaaa aacaaaaaaa
     9301 gtggtacaca gaagcaggag taacatacag aaattactga tttttttcat aaaagtgcct
     9361 ccactacagt tttccctctc caaataggag agggaagaat tttactcaaa tccatagaaa
     9421 tattccatta ctgttggcgg aatcttggtg agggaagctc tagcccatgc ctcaggtttt
     9481 gcataatcct tagaggttct acccccatgt ctaacagttg ctgtatgata tcgagtagaa
     9541 tgtaagtaat cagaatatcc aaaagttcct gtccaaccta ctccatagtt ccattgacca
     9601 ccctcaaccc atactgctaa agcatttgta gtagcaagta taccacatac cattaaagat
     9661 gcaacaccaa ttttaactaa ttttctcatg atttatttct cctattatcg agagctgttc
     9721 cgtaaaaaca gctatagtaa tttatcaaca agtatcgtag tccattggac tcaccttcct
     9781 tctatctcat ttcatttttt aacaacgaac ttactcttaa ccgggagaat ggtgcgcttc
     9841 tgtatcaggt ccttgaacaa ccagagtagt attaagcaca ctctaactat tactcaagaa
     9901 tcagtccaat aaacaatatg gatagcgctt tcaaattttt aaactcctat cccgtccttt
     9961 tatctatata ataagcataa gcgaaaatat aataactgtc aagtatctga agtgaatttt
    10021 ataaaaaaat tacaagccaa atttgtaaag tttacactaa gccgctaggg caatcgtcta
    10081 tcagaatgtc cgtttatttg tcaataatcc gagaaaatct tgcaacgctt agaagtctat
    10141 aaaaactatc aacatttata tgacttgcga atagcaatcc tgctaaacct ttccacactc
    10201 tatctataca atcaagataa aaacatgtgt aagcaaatct gctacacttt actggaggac
    10261 gccaagaata agaaaagcta cgataggctt gctatctgct atgtccgtat tgggatttgt
    10321 acagataatg ctaaacttat ccaaaaaggt ttctcacttc tggagctgac cgaggaaact
    10381 tctatgctgt ctcatctcaa aaaagaagta gagacccatt atcaaccaaa gaaattataa
    10441 aaaaagtcga gggagctcct cgacctttta catattattt gttcgttagt tcttaatacc
    10501 agccattgtt aagccagaag tttttagcag cagtccatga accgtaacgt cctgcaacgt
    10561 aggcatctgc tacacgttct tggttttcag ctgagtagtc accgttcagg tatgaatctg
    10621 ttaattggta acgtccgata taacgtccat ttgtagctgt atagctacca cctgattctt
    10681 tttgagcgat ccattctttg gcttctgctt cagatccgct tacagttgaa acaactgttt
    10741 cacttactac tggagctgaa acagtttcat cttgagcggc tggtgccgca taagtagctg
    10801 gcgctggtgt tgcaacaggc gctacagggc catcgataac caactcttga tcaacataaa
    10861 tcaaatgaat gttatcaatg tggttgtttt ctgccaattt ttcaactgtt gtgttgtgag
    10921 tttcagcgat ttctgaaagt gtatcacctt ctttaacagt gtaagttgat gattcttgag
    10981 cagatacaaa tgatggagca aatactgcaa acaaggcagc tactcctgca agagttgctt
    11041 taatcttttt agttattgat ttcatattcg aaaattctcc ttctttctat agttctatca
    11101 taccctttaa atattaccgt ttcttgacac ttttatgtag aaatattaca aaattatttt
    11161 ttatttccct aaataaggtg ttttttgtca taaaagatac tatttttatg ctatttgagg
    11221 tattagaaag gttttcatcc acaattaaag ccaagcccct cattctttga tataatagag
    11281 ataagaattt ttataagggg aaactgatga aatcacttcg ttttcaatct gtctttgata
    11341 tcatcggacc agttatgatt ggcccatcta gtagccatac cgctggtgct gttcgtattg
    11401 ggaagattgt ctcttccatt tttgatgata ctccgacaga agttgaattc caacttttta
    11461 actcatttgc caagacctat cgtggtcacg gaacagacct agcccttgtt gcaggtattt
    11521 taggaatgga tacagatgat cctgaaattc caaatagtct ggaaattgcc cacaagcgtg
    11581 gtatcaagat tgtctggacc attcagaaag acagcaatgc ccctcaccct aacaccacta
    11641 aaattactgt taaaaatgcc cacaagacca tcagcgtgac tggtatttct atcggtggag
    11701 gaaatattca ggtaaccgaa ctcaatggtt ttgccgtctc tctcaatatg aatacaccga
    11761 ctatcatcat cgttcatcaa gatattccag gtatgattgc ccttgttaca gaggcgcttt
    11821 cccgctatgg tatcaatatc gcccagatga atgtcactcg tgaaaaagct ggtgaaaaag
    11881 ccattatgat tatcgaagtt gacagtcgca actgtgatga ggctatcgaa gaaattcgaa
    11941 aaatccctca tctccacaat gtcaatttct ttaaatagga ggaagcatgt tttattctat
    12001 caaagaattg gtcgagcaag cagatctaga ctttcaagga aatgtcgcag aactcatgat
    12061 tacaacagag tttgaattga ccggtcgcga acgtgaagaa gtcttccttc tcatggaacg
    12121 caatctggaa gttatgaaag cctctgtcca acttggcctc aatgaaaata aatctcgtag
    12181 tggcctgaca ggtggagatg ctgccaaatt ggatcactac atcgaaaacg gaaaaactct
    12241 gtcagattat acgattctct cggctgcccg aaatgccatc gcagtcaatg aacacaatgc
    12301 caaaatgggc ttggtctgtg ccactccaac cgctggaagt gctggctgtc tgccatccgt
    12361 tctcactgct gctattgaaa aattagacct cagccacgag caacaattgg atttcctctt
    12421 tgctgctggt gcctttggac tagtcatcgc aaacaatgcc tccatctcag gtgctgaggg
    12481 tgggtgtcaa gctgaagttg gttcagcctc tgctatgagt gctgccgcct tgactctggc
    12541 tgcaggtgga acaccttatc aggccagtca agctattgcc tttgtcatta aaaatatgct
    12601 aggcctcatc tgtgaccctg ttgcaggttt ggtcgaagtt ccctgtgtca aacgtaatgc
    12661 catgggagct agctttgctt tcatcgcagc agacatggcc ttggcaggta tcgaatctaa
    12721 aatccctgtg gatgaagtga tcgatgccat gtaccaagta ggagcaagca tgccaactgc
    12781 ctttcgtgaa acagctgaag gtggactcgc taccacccct actggtcgtc gcctccaaaa
    12841 agaaattttc ggagaataag cttatcaaat aggagaaacc atgacctcta tcacagcgat
    12901 ttttttcgat ttggatggaa ccctcgttga tagttctatc gggattcaca atgcctttac
    12961 ctataccttt aaagagctgg gggtgcctag ccctgatgcc aaaactattc gtggttttat
    13021 gggaccacct ctcgaaagta gttttgcgac ctgcctgtcc aaagaccaaa tttctgaagc
    13081 cgtgcagata tatcgttctt actataaggc aaaaggcatc tatgaagctc aactctttcc
    13141 tcagattata gacttgcttg aggagttatc gagcagttat ccactctaca tcaccacgac
    13201 aaaggataca tctactgctc aagacatggc aaaaaacttg gaaatccatc atttctttga
    13261 tggcatttat ggttctagcc ctgaagcacc ccataaggca gatgtcattc accaagcctt
    13321 gcagacacat caactagcac cagaacaagc catcatcatc ggagatacca agtttgatat
    13381 gctgggagct cgagaaacag gtattcagaa attggccatc acttggggat ttggagagca
    13441 agcagatcta ctaaactatc aacctgatta tatcgctcac aaacccttag aagttttggc
    13501 gtattttcaa tagcatagac tgggtaacaa ttccatttca gaagaaaatg aagtaatact
    13561 caatgaaaat caaagagcaa actaggaaac tagctgcggg ctgctcaaaa cactgttttg
    13621 aggttgcaga tagaactgac gaagtcagct caaaacactg ttttgaggtt gtggatagaa
    13681 ctgacgaagt cagctcaaaa cactgttttg aggttgtgga tagaactgac gaagtcagct
    13741 caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat atacggcaag
    13801 gcgacgttga cgtggtttga agagattttc gaagagtata agtctctaca taataaaacg
    13861 catattacca aggttgtgta acttgatact atgcgttttt cttttttatt caatgtgggt
    13921 tgtttgatta gcaaaggcga taatagcttg cttcaactca tctccactga gagtgcggaa
    13981 ctctccaatc ttttgattga tggattctaa aggcatgaca ttaaccttac caacgaaaat
    14041 cttatccata acttgattat caacgagttc ggttgatacc aagagttctt cgtagagttt
    14101 ttcacctggg cggattccaa cttcaacgat tggaatttca ctttcagtgt ggccacttag
    14161 aagcaccatc ttcttggcca agtcataaat cttgactggt ttgcccatat caaggataaa
    14221 gacttcccca tctttggcat aagcaccagc atggataacc agacggctag cttctggaat
    14281 ggtcataaaa taacgggtca tgcggaagtc tgtcaccgtt acaggcccac cttcagcaat
    14341 ctgacgttca aagactggaa tgacactacc acggctacca agaacattcc caaaacgaac
    14401 tgcacagtag gttgattggc tacgttggtt aaagccagtg acaatcaact ccgccacgcg
    14461 cttggttgct cccataacat ttggtggatt gactgcctta tctgtcgaaa tcataaccat
    14521 cttagacact ttagcttcat caacagcctt agcaacattg taagttccac ggatattgtt
    14581 tttgaaggct tcttttggat tgcgctccat cataggaaca tgcttgtggg ctgccgcatg
    14641 ataaacaata gcaggtttgt actgctcaaa gacttgcaac aaacgatcat agtcttgaat
    14701 gtccgcaatc acaggtacat aatcaatccc ttggaactta cgaatcaatt catgataaac
    14761 aaggtagatt gagttttccc catgaccgag caagacaatg cgttcaggat tgaagcgact
    14821 aacttgacga cagatttcag aaccgattga acctccagct cctgtgacta agatggtctt
    14881 acctgtcagt tctgcaccca gacgcgattc gtcaagacgg atttcctgac gacccaaaag
    14941 gtccgtaata tcaatttttt ggaagccagt acctgcttgg tgaaggccct gaacaacagt
    15001 ttcaacctta ggcatcttgt aacatttgac acccagctta ttacacatct gcaagatacg
    15061 ctcatattct gacggatcca gcgacggaat cgcaacgatg acacgctcga tttgatggcg
    15121 tttggctaat tcaggcagat tgtcataaga gcccaaaaca ggaataccac caagtttttg
    15181 accctttttc ttagaatcct tatccaaaat accgaccagt tctaattcac tggttggatg
    15241 ttggtaacta tccataaaaa gagccccacc atcaccggca ccaatcaaga aggtccgacg
    15301 gtgttctcca tcaccactac cttttttgcg tctggagtag attaactgcc aagtaatccg
    15361 tggcaataaa atcaagaagg tactcaacaa gataaagaga atgatgaaac ggatggagaa
    15421 gagtggcaag aaggcataac agatactata tgacaagaca ctgctagcag tcacaccaaa
    15481 aaagattttc atgaaatccg taatcttgct gtaacgacta atgctcgcgt tcaaccccca
    15541 aaaaccaatc atcaattgat agaacaggaa ggccaaactc gtatagataa tgtagtcaac
    15601 aggtgctgga ttaatcagcc cataaaataa aatataagat acaatgatgg aaaccaccat
    15661 actgaaaata tcaaatattc cccagaaaac ctgcttttgt tgtttattta aaatttccac
    15721 cagatcaatc acataatctg ttagtttttt attcatagaa atctactcct ccttaaaaga
    15781 gttttactat attgttatta tagcatattt ttgtttattt ggcttatttt atccaaataa
    15841 attattgttc tcttgtactc cttcttccat ttaaatcctc taattaaacc tacaatcgtc
    15901 ccaaagccat aagcaaagtg aatggaaaat aaaagaaagg gcatcacaat tagaaatcca
    15961 tttttatgtt ttaataaagt cagcaaagtg agtagtgaca aaagtagaaa ataggcacct
    16021 aatagtaaag ttatgaatac gaatgtgatc ggtaacaatg ctagactaaa cacaagactc
    16081 aaaacaaata aacaaggaac atagtgaaat aatgataaac acttaaactg aacatgactt
    16141 gtcaagccaa tccacaaacc atttaaatac ttttgatgca gcattttctt gaatgttggt
    16201 cgaatatact gataagatag aatacttggg ctatagcgga ttttataacc atattctcga
    16261 attctataat gaatatcatt atcttcagtt cggccaagtt gctcatttac taaaccaacc
    16321 ttctggaaaa cctctcgttt atacattcca tgaaaaatag aagaaacata tctatcctca
    16381 gaactatttc gataattggc aatgctactg ccaaacatat tttcctcaac aagatgcaag
    16441 gtctctgccc attttccttt tccttcgaca atcgtcggtc taggcccccc acagacaaat
    16501 tcaccttgtt gaataatagc cacattgttc attacaaaac tctcagtaac ttttgaatga
    16561 gcatcaattt ttaaaataag gtcccctaca gaatgtttaa ctcccaggtt aaaaccacta
    16621 gcttgatttt tcttaggatt gttatacaat ctaattgagt taaactctgt atcttccttt
    16681 ataaattgct gaatgatagc tgtggtccca tctgtggaca tagcatttat aaatagaatt
    16741 tcaatattct ctttaggata agtttgattt tttaagtctt caattagacc aggcagatat
    16801 ttttcttcat tgtatgcact gattacaatg gatacgagaa gactttcaac attttgagtc
    16861 actactactc tcctgaattt ttccttccac cattctatca taattttcaa gactttccca
    16921 tttttatctt gaaagccaga aaccttactt gacattatag tgaaaaagcc ttaaaataag
    16981 ctgttattaa aatcagctag aagaggtatt atatgaaaaa gcaatcactc ttttttgttc
    17041 caggtattat cctgattggt gtttccttgc gaactccttt tactgtttta cccattattt
    17101 tgggaaatat ttcgcaaggt ctggaggtag aagttagttc gcttggtgtc ttgaccagcc
    17161 tgcctctcct tatgtttacc ctcttttcac cattttctac ccgactggct cagaaaatcg
    17221 gcttggagca tctcttcacc tacagcctct tcttcttgac catcggctca cttattcgac
    17281 taatcaatct gcccctgctc tatctaggaa ccttgatggt tggggcaagt gtcgcagtca
    17341 tcaatgtcct gcttcctagt cttatccaag ccaatcaacc aaagaaaatt ggttttctga
    17401 ccaccttata tgtaacgtct atggggattg caacggctct ggcttcctat ctagctgtgc
    17461 ccattacaca agccagttct tggaaaggac ttatccttct cctcacgtta ctctgtctag
    17521 caactttttt ggtctggctc ccaaatcacc gctataatca tagactagct ccacaaacca
    17581 aacaaaaaag tcaaataaag gtcatgcgta ataaacaggt ttgggcaatt attatctttt
    17641 caggttttca atccttgatc ttttacaccg tcatgacctg gttacctacc atgtctatcc
    17701 atgcaggtct atccagtcac gaagctggct tgctgacttc tatcttatct ctgattagca
    17761 ttcctttttc aatgaccatc ccaagcctga caaccagttt atctactcgc aaccgtcagc
    17821 tcatgctcac tctggtttca ctagctggtg tggtcggcat ttccatgctc tttttcccaa
    17881 tcaataattt catttactgg cttgccatcc atctcctcat cggaaccgca accagcgccc
    17941 tcttccctta tctcatggtc aacttttcac tcaagacaag cgcccctgaa aagacagccc
    18001 aattgtccgg cctatctcaa acaggaggct atatcctagc agcctttggg ccaaccctct
    18061 ttggttacag ttttgacctg ttccactctt gggtaccatc tgtagctgcc ctcttgctca
    18121 tcgatatcct gatgactatg gccctcttta cagtggacag agcggataag atcctttaaa
    18181 cttctagttt tagctagaag ttttttatat ataaaaattt tacacatttc tcttgacagg
    18241 gctttctttt agatgtacaa tgtatgtgta gaaaaattat atataaaaat cttacacatt
    18301 agaaaaggag gtttcccatg tactttccaa catcctctgc cttgattgaa tttctcatct
    18361 tggccgtact ggagcagggt gattcttatg gttatgagat tagccaaacc attaagctga
    18421 tcgctaatat caaagaatcc acactctatc ccattctcaa aaaattggaa ggcaatagct
    18481 ttctgacaac ctattctaga gagttccaag gtcgcatgcg caaatactac tccttgacaa
    18541 acggtggtat agagcagctc ttgaccctaa aagatgaatg ggcactctat acagacacca
    18601 tcaatggcat catagaaggg agtatccgcc atgacaagaa ctgaatacct gactcagcta
    18661 gaactctatc tcaagaaact acctgaagct gaccgtatcg aagccatgga ctatttcaga
    18721 gagctctttg acgatgctgg agtcgaagga gaagaagaac tcatcgctag tttgggaact
    18781 cccaaagaag cggcccacga agttctatcc aatcttctcg ataaaaaaat caatgaagca
    18841 cccgctcaaa aaaataaccg acaaatttta catatcgcct tgttagccct ccttgcagca
    18901 cctatcggca ttcctctggg aatcgccatc ctcgtgaccc tgttcgcaat ccttgtagcc
    18961 gctttgactg tcattctggc tttctttgca gtttccatac tgggtatcat cggcggattc
    19021 ctatttttag ttgaaagttt cactatcctc gcccaagcca aatcagcctt tatcttgatt
    19081 tttggttctg gtttactggc tatcggtgct tcttcgctag ttttacttgg catttcctat
    19141 gtagctcgct tcttcggtct actcattgtt cgtctggtac aatttgttct taaaaaagga
    19201 aagagaggta atcagcatgc gtaaatggac aaaaggattt ctcatctttg gtgtggtgac
    19261 taccgttatc ggctttatcc tgctttttgt aggtatccaa tctgacggga ttaagagcct
    19321 actttccatg tccaaagaac ctgtctatga tagccgtacg gaaaagctaa cctttggcaa
    19381 ggaagtcgaa aacctagaaa ttactctcca ccaacacacg ctcaccatca cagactcttt
    19441 cgatgatcaa atccacattt cttaccatcc atctctttct gctcaccatg atcttatcac
    19501 caatcagaac gatagaactc tgagtctcac tgataagaaa ctgtctgaaa ctccgtttct
    19561 ctcttctgga attggtggga ttcttcatat cgcaagtagc tactctagtc gttttgaaga
    19621 agttattctc cgactaccaa aagggagaac tctaaaaggg atcaacatct cagccaatcg
    19681 cggacaaacc accatcataa atgctagcct tgaaaatgcg accctcaata caaacagcta
    19741 tatcctccga attgaaggaa gtcgtatcaa aaacagtaaa ctcacaacgc ccaatatcgt
    19801 taatatcttt gatacagttc ttacagatag tcagctagag tcaacagata atcacttcca
    19861 cgctgaaaat atccaagtcc atggtaaggt tgaactgact gccaaagatt atctcagaat
    19921 catcctagac cagaaagaaa accaacgaat taactgggac atctcaagca actatggttc
    19981 tatcttccaa ttcacaagag aaaagcctga atcaagaggt acggaattaa gcaaccctta
    20041 caaaactgaa aaaaccgatg tcaaggatca actcattgcg agatctgatg ataatattga
    20101 tctaatatcc acaccaagca gacgttgaca aaaacgctta catctgctac tatggaagca
    20161 tatttatcta accaaaagga ggttctacca tgaaacaaga atggtttgaa agtaatgatt
    20221 ttgtaaaaac aacaagcaag aacaagcctg aagagcaagc tcaagaggtt gcagacaagg
    20281 ctgaagaaac gatagccgat ctcgatacac caattggaaa aaatactcaa gtagaggagg
    20341 aagtctctca agctgaagtc gaactggaaa gccagcaaga agagaaaatt gaaactcctg
    20401 aagacagtga agcgagaaca gaaatagaag aaaagaaggc atctaattct actgaagaag
    20461 agccagacct ttctaaagaa acagaaaaag tcactatagc tgaagagagc caagaagctc
    20521 ttcctcagca aaaagcaacc acgaaagagc cacttcttat cagtaaatct ttagaaagtc
    20581 cttatatccc cgaccaagct ccaaaatcta gggataaatg gaaagagcaa gtgcttgatt
    20641 tttggtcttg gctagtggaa gcgatcaaat ctcctacaag taagttggaa acaagtatca
    20701 cacacagtta cacagccttt ctcttgctca ttctgttttc tgcatcttcc tttttcttta
    20761 gtatctatca catcaaacat gcttactatg gacatatagc aagcattaac agtcgcttcc
    20821 ctgagcagct agctccttta actctttttt ctatcatctc tatcctagta gcgacaacac
    20881 tcttcttctt ttcattcctc ttgggtagtt tcgttgtgag acgatttatc caccaggaaa
    20941 aggactggac gctagacaag gttctccaac aatatagtca actcttggca attccaatct
    21001 tcctcactgc tattgctagt ttctttgctt tctttgatag cctacgattt acagccctct
    21061 tgtgtgtgat tagcattgga atcattctgc ttgccagtct ccatatcatt acaagaccaa
    21121 gtcaagcaag tgaaaccgac tccttctatc aattattctt gtctgtcctt gtgaacggag
    21181 ttattatcct cctcttcttt gtagctgaag tggcactgat tggagattat cttcgtatct
    21241 tggcctttct ttaaaattca atcctgtcat ccttggcagg atttttctat ttcaaaaaag
    21301 caagtcgatt gacctgcttc tgctttactt ttcttgtgct aatgttttaa aatcttgtcc
    21361 taggatgggt tgtacttcta attgattggc gtctagttgg tggtaaaatg ctgatggtag
    21421 tgactctagg aattttgcat agtccaagcg ggcgatggct tcatagtctt ctggtttaga
    21481 gccatctcct gtgatttgaa ccaagtcgat ctcccactgc acttccttat ccaccaattg
    21541 ctccatatag gcagcaggaa caaatggttc tctcggtaaa acggtcttga cgccttgagc
    21601 caaatgataa acaccgtgca cttgcccttc tccatcctga tagaaggaaa ctcttgcaaa
    21661 gtaggcatct gtctcttgaa ccgcacgcac acgcgcttca aactgggcca agccatctgc
    21721 ctctaaaaag cttttcaagt tctcacgact aaagaaaata ggattaaaaa ttccttggca
    21781 aatcgtaaaa cgagctacag ggtctgctag ataggcttga atacttgctt ggaaataagc
    21841 ttcaaaatca aaaccatcta gcccttcaat atcagtccct gtataagcaa gcaaagcatc
    21901 taaaaatgac ttgataatct gccagtctgt ctttgttagt aggtcaggaa gatcgacacg
    21961 gtaagccttt tgaccatcag cataactgac cttaaaaaga aattgtgatt gccccattat
    22021 cgcacagacg attaagaggc tgacggagat agactacatc atagctatgt gactccaaac
    22081 cgtctagcaa ggccaagatc gacttggcat tcaaaatctc ttgttctcct aaaatgctct
    22141 gtttatttgg aataaaaaat gtttttgcca taactggact cctttgaaat cgtttacata
    22201 cagtatacct tatttttctg aaagatacaa aaacaaactt tatattcttc gaaaatctct
    22261 tcaaaccgcg tcagcttcgc cttgccgtag atatatgtaa ctgacttcgt cagtcttatc
    22321 tacaacctca aagcagtgct ttgagcagcc tgcagctagc ttcctagttt gctctttgat
    22381 tttcattgag tattagattt ttgagtacaa agcatagaaa aacagcccct gaggactgtt
    22441 tgatcttata cagtagctgc ctgatccaag ctttcaccga tagcggctag gcgctcaatc
    22501 acttcagctt gtgtcaattc attttttgaa acatagcggt tacgtgggtg aacacggcac
    22561 tcgtgtgagc atccacgaag gtacttgtct tcattttctt ctgatgtcaa gatacgacgg
    22621 ttacagaagg gatttccaca gttgacataa cgttcacatg gtgttccatc aaaccagtct
    22681 ttccctacga tggttgggtt gacatggttg acatcaacgg caatacgctc gtcaaagacg
    22741 tacattttcc catcccaaag ctcaccttga acttctgggt ctttaccgta agttgcgatt
    22801 cctccgtgca attggccaac atctttgtaa ccttcacgaa ccatccagcc tgagaatttc
    22861 tcacagcgaa caccacctgt acagtaaacc acgacacgct tgtccatgaa tttttctttg
    22921 ttgtcacgga cccattgtgg taactcacgg aagttgcgaa tatctgggcg aatagcccca
    22981 cggaaatgtc ctaggtcgta ctcataatcg ttacgtgtgt caaggacaac ggtatcttta
    23041 tcaagaagcg cttctttgaa ctcttttgga gacaagtaag cacctgttgt ttcaagtggg
    23101 ttgatgtcat tgtcaaagtc gttgtcttcc aaaccaaggt ggacaatttc tttcttgtag
    23161 cgaacaaaca tcttcttgaa ggcttgttca ctttcttcgt caatcttgaa ccagagatct
    23221 tccattcctg gaaggctgtg aacgtagtcc atgtattttt gagttgtttc atagtcacct
    23281 gaaactgttc cgttaattcc ctcgtcagcg actaggatac ggcctttaag gccgattgat
    23341 ttacagaaag ccaagtggtc tgcagcaaat tgctctgcat tttcaattgg agtataaagg
    23401 tagtaaagta agacacgaat atcttttgcc ataagatttg ttctcttttc tattcttaaa
    23461 ttttctaaat tttttattta tctacactag tatacctgct tgagaaaacg aatgcaattt
    23521 atttgactgg aaattgtaga ggattctcga aatttcctga atggttaaaa taaggacaag
    23581 agaaaacagg gatatctata tccttgtgcc caaaaaacca ctgccctccc cagaccaatc
    23641 tgaggaaagc agtgattctt attttaggag ttaggaatga atacacgaaa tcaatttagc
    23701 tgattatttt ttgtttttca agaattcatc gtattgtttt tgcatttcgt tcaatacttt
    23761 ttcgtaggca ccttcagatt tcaatttttc catcaattct ggaatcgctt tatctgggtc
    23821 tacagtacca gtgttgatag ctgtatcaaa ttgttgcatt gtgttagcaa tagctgagat
    23881 ttcagatttc acattgtcag tattaaagat aaatccaagc gctggagatt ctttagcttc
    23941 tgccaattct ttcttagaat tttcgatttg ttggtctgta acgttttcgt tgatgtaaag
    24001 gatccagttg ttaccagtgt tccatccacc catgtgagtg tttcctttgt agccatcaag
    24061 aacgcgaaca cggttttctt taccttcaat tttttcccag ttcttgcctt ctggaccgta
    24121 aacaagaccg ttcaagagtt ctgggttcgt attcaagagg ttcaagattt ccattgattt
    24181 ttctttgttc ttagagttgt ttgagatgac aaagttagca acttgtgttg tttggttttt
    24241 cttgatgaag ttagtaattg gtttgatttg gatatctttg ttggcaacac gtgaaagcaa
    24301 gctgttaccg tagtcagctg gtcctactgt ttcttcacga acgaaccaag tatcttgttg
    24361 aaggtcaaag gaagtatcgc ttgttgcgac gtcttttgga atgtagccag cttcatagaa
    24421 tttgtgaaga gtcttcaagt gttctttgaa acgaggtact tcgtaacggt ttacaacttt
    24481 agtagtatcg ccttcaaggt caataacgaa tggaagaccg tttgctactg ggtagtcaaa
    24541 gttatcagat gggatgaaaa ctttaccaat agcaaatggt actacgtctg gagctttttc
    24601 tttgatttgt ttcaagactg gctcaagagt ttcgtaagaa gtaacacctg aaatatcgat
    24661 accatatttg gcaaggagag ttccgttgaa ggcaaagttt tgagatgatg ctacgttggc
    24721 tgcaactggt acagcgtaaa tcttaccatt tacagtatta cccttgatat aagctggatc
    24781 aagtgccttg taaaggtctt taccttcttt tttgtacaat tctgtcaagt cagcataagc
    24841 acctttttga gcatttacaa tatagttatc tgcaaaggcg atatcatagt tttcaccaga
    24901 tgatgtgata actgacattt tcttaccata gtcaccccag ccaaggtatt ggatatccaa
    24961 tttagcacca actttttctt cgatgatttt gttggcattt gctaacaatt catccaagtt
    25021 atctggtttg tcaccgattt ggtacatttt gataacaggt ttgtcacctg aatcagcagc
    25081 ttttttgctg ttacctgtca aatttccaca agcagcaaga cctgcagcca gagcgactac
    25141 actagcagat gcaaaagcat attttttcca gtttttcatg ataaaaactc ctttttttat
    25201 ttttaaactt ataaacaatg taatgatctt atactcaatg aaaatcaaag agcaaactag
    25261 aaaactagtc gcaggctgct caaagcactg ctttgaggtt gtagataaga ctgacgaagt
    25321 cagttacata tatctacggc aaggcgacgt tgacgcggtt tgaatttgat tttcaaagag
    25381 tattaacttc acacaaggga agttgggaac tgagaaatgt tctttttcaa taagcactat
    25441 tctttcacac caccgatagt caaacctttt acaaagtagc gttggaagaa tggatataaa
    25501 atcgcgattg gaagggtcgc aaccacaacc atggccatac gacctgtttc tttcggtaga
    25561 gcaactccca gttgaccagt caagccgacc gctttggcaa tgtagtccat attttgttgg
    25621 atttgcatga gcaaatattg caatggatac aagttgtcac tcttgatgta aagaagggcg
    25681 ttgaaccagt cattccagaa accaagagct gtcaaaagcg tgatggttgc gatacctggt
    25741 agtgacaatg gcaaacagat ttggaagaaa atccgggcct cactggcacc atcgatacga
    25801 gccgattcga gaatggcttc tggaatggtc ttcttgaaga aggaacgcat caagatgata
    25861 ttgaatggtg agagaagcat tggaacaatc aaggcccaaa cagtgtcacc aagctgaagt
    25921 acacgggtca ccatgatata acctggtacc aaaccagcgt tgaacaacat actgagaagg
    25981 acgaagatgg taaaaaatct gcgatactta aaggttgtcc gtgaaatagc gtaggcatag
    26041 gttgttgtga taaagacatt tgtcaatgtc ccaactacgg ttacaaagac agagatgaag
    26101 agggcttgta ggattttatc cttaaactgt gccaaaaact caaaaccgtc taagccaaat
    26161 tgggatggga agaagctata gccgtattgg aggaggcttt tctcgtctgt cactgaaata
    26221 atgataacga atacaaaagg taggatacaa gagagggcaa tcaaacccga aatgatactg
    26281 aagaagatat ctgctttctt actgaaggag tgaatgccga cattatcaat tttttctttt
    26341 ttaattttct tttttgccat attctcctcc tttctagaac aaagctgagt ttggatcgac
    26401 tcgtcttgca agcaagtttg ataggataac cagaatcaaa ccaacaacgg attggtaaag
    26461 accggctgct gcagccatac cgatatctgc tgtctgagtc aaaccattaa aaacatatac
    26521 gtccaaaacg ttggttacat tgtaaagctg accagcattg tgtgggattt gatagaagag
    26581 accgaagtct gcgcggaaga tatttccgac tgcaaggatg gtcaatacag ttacaagcgg
    26641 agtcaactga ggaatggtta cgttgcgaat acgttgccac ttgctagctc cgtccactgt
    26701 cgctgcttcg tagtaggttg gatcaattcc catgatcgtc gcatagtaca tgacactgct
    26761 atatccaaaa cctttccaaa tacctaggaa aagtaggaga tagggccaga tgcccaggtc
    26821 agcgtagaaa ttgacttctt tgagaccaag actttccaat agatgattga acaccccttt
    26881 atcaatattt aggaaggcat ctgtaaagaa actgatgata acccaagaca agaagtaagg
    26941 gaacaacata gaagtttgga aaatcttcac cattctctta gaacggagct cgctgaggat
    27001 aatggcaatc cctacagata caactaaacc tagaaagata aagccaagat tgtagaggac
    27061 agtatttcgt gtgataataa aggcgtctct tgaactaaat aagaatctga aattatcgag
    27121 tccgacccat ttactattta tgatactatc tatgaaacca ttactggtca tgtggtagtc
    27181 tttgaaggca accacgttcc caaatactgg aatgtaaaag aatagaatca accagagtgc
    27241 ccctggcaaa accatcaaga gaaagatcca gttgtctctc aatgtttttg aaaacttttt
    27301 cataatttcc tcccttttta ttttgatatc catctaaaaa ttctttttta gacttttgat
    27361 aacgattaca ttattagtat actcctattt gcaggttagg ttaaactcct aattatagaa
    27421 aaaactccac aaattatgta gcagatttaa aactttatca ccactataaa acaaatgtcc
    27481 taaatcaatt gtttatttta tctctattag cccagtgatg gcgtcactct gttataagca
    27541 tccaacaacg gggtatactg aaaaatctcc agactaggga actcagcgat agttcctaat
    27601 ctggagattt ttaatatgtt attaggcgtt tgctttcaac ttagcaataa cctctttaag
    27661 attatcaatc aactctgctt cagtatgctc agagcctttt tcatctgcca agaacaaaac
    27721 tgctttttga agttcttctt gagagttttc aaggacatcc ttatctactg tttcaaggtt
    27781 tgagtcttta agaagtttac ttaattcctt ggctaatttc ttgagtttga tttgcagact
    27841 catcttctcc tgctgtttct ttgcccgctg tttgtcctcc atccttagtt gctgactggc
    27901 tttccttaat ggactctagg gaagcaatgg catctttgac tgtttgcaag atatcacgta
    27961 aaccttgctc tgtcaaacta tcatctgcaa gagctttctt agcctctgcc aaaaccagac
    28021 gtgctgaatc tgtggtagga ttcgatacac ctgtcaatga tctcaaaaga ttttctaagg
    28081 tttgagtctg cttactaata ctagactaaa atcaaaaagc attacataac agtgatatga
    28141 aatcaactaa agaagaaatc caaaccatca aaacactttt aaaagactct cgtacagcta
    28201 aatatcataa acgccttcaa atcgttctat agtaaaatga aacaagaaca gggcaaatct
    28261 tataaagaga ttatagaact tttatagtag tttgaaataa gatgtgaaca actctatcag
    28321 gaaagtcaaa ttaatttata gaaatatttt agcagccaag gtgtactgtt atagattcaa
    28381 tacact
//
LOCUS       DAVLDI010000026        26871 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLDI010000026 DAVLDI010000000
VERSION     DAVLDI010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26871
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.026"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            134..364
                     /gene="blpU"
                     /locus_tag="VXD01_001143"
     CDS             134..364
                     /gene="blpU"
                     /locus_tag="VXD01_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV0601557.1"
                     /translation="MNTKMMSQFSVMDNEMLARVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            367..486
                     /locus_tag="VXD01_001144"
     CDS             367..486
                     /locus_tag="VXD01_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0601558.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            783..947
                     /locus_tag="VXD01_001145"
     CDS             783..947
                     /locus_tag="VXD01_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601559.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            944..1348
                     /locus_tag="VXD01_001146"
     CDS             944..1348
                     /locus_tag="VXD01_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV0601560.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQLIAYIGAVLCLIIMLLLMWGLKYYKK"
     gene            1546..2351
                     /locus_tag="VXD01_001147"
                     /pseudo
     CDS             1546..2351
                     /locus_tag="VXD01_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            2501..2755
                     /gene="blpM"
                     /locus_tag="VXD01_001148"
     CDS             2501..2755
                     /gene="blpM"
                     /locus_tag="VXD01_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV0601561.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            2771..2974
                     /gene="blpN"
                     /locus_tag="VXD01_001149"
     CDS             2771..2974
                     /gene="blpN"
                     /locus_tag="VXD01_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV0601562.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            3218..3367
                     /gene="blpO"
                     /locus_tag="VXD01_001150"
     CDS             3218..3367
                     /gene="blpO"
                     /locus_tag="VXD01_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV0601563.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCTAGVAYGAIDG
                     CATTV"
     gene            3471..3590
                     /locus_tag="VXD01_001151"
     CDS             3471..3590
                     /locus_tag="VXD01_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV0601564.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            4376..4759
                     /locus_tag="VXD01_001152"
     CDS             4376..4759
                     /locus_tag="VXD01_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV0601565.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVFYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            4811..5500
                     /locus_tag="VXD01_001153"
     CDS             4811..5500
                     /locus_tag="VXD01_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0601566.1"
                     /translation="MKKYQLLFKTSAILSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            5542..5775
                     /locus_tag="VXD01_001154"
     CDS             5542..5775
                     /locus_tag="VXD01_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601567.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            5926..6537
                     /locus_tag="VXD01_001155"
     CDS             5926..6537
                     /locus_tag="VXD01_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0601568.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            6698..7492
                     /locus_tag="VXD01_001156"
     CDS             6698..7492
                     /locus_tag="VXD01_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV0601569.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            7489..8124
                     /gene="trmB"
                     /locus_tag="VXD01_001157"
     CDS             7489..8124
                     /gene="trmB"
                     /locus_tag="VXD01_001157"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV0601570.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            8251..8730
                     /gene="rimP"
                     /locus_tag="VXD01_001158"
     CDS             8251..8730
                     /gene="rimP"
                     /locus_tag="VXD01_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV0601571.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            8774..9910
                     /gene="nusA"
                     /locus_tag="VXD01_001159"
     CDS             8774..9910
                     /gene="nusA"
                     /locus_tag="VXD01_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV0601572.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            9932..10225
                     /locus_tag="VXD01_001160"
     CDS             9932..10225
                     /locus_tag="VXD01_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV0601573.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            10218..10517
                     /locus_tag="VXD01_001161"
     CDS             10218..10517
                     /locus_tag="VXD01_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV0601574.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            10534..13326
                     /gene="infB"
                     /locus_tag="VXD01_001162"
     CDS             10534..13326
                     /gene="infB"
                     /locus_tag="VXD01_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV0601575.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            13577..13927
                     /gene="rbfA"
                     /locus_tag="VXD01_001163"
     CDS             13577..13927
                     /gene="rbfA"
                     /locus_tag="VXD01_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV0601576.1"
                     /translation="MVNHFRIDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            14206..14985
                     /locus_tag="VXD01_001164"
     CDS             14206..14985
                     /locus_tag="VXD01_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601577.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            14987..15169
                     /locus_tag="VXD01_001165"
     CDS             14987..15169
                     /locus_tag="VXD01_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601578.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            15166..15306
                     /locus_tag="VXD01_001166"
     CDS             15166..15306
                     /locus_tag="VXD01_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601579.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(15512..15589)
                     /locus_tag="VXD01_001167"
                     /pseudo
     CDS             complement(15512..15589)
                     /locus_tag="VXD01_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            15620..15853
                     /locus_tag="VXD01_001168"
     CDS             15620..15853
                     /locus_tag="VXD01_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV0601580.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            15853..17187
                     /locus_tag="VXD01_001169"
     CDS             15853..17187
                     /locus_tag="VXD01_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV0601581.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            17197..17451
                     /locus_tag="VXD01_001170"
     CDS             17197..17451
                     /locus_tag="VXD01_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV0601582.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            17547..17942
                     /locus_tag="VXD01_001171"
     CDS             17547..17942
                     /locus_tag="VXD01_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0601583.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLTLKGIGPATIKKLKENGIKFK"
     gene            18354..18803
                     /locus_tag="VXD01_001172"
     CDS             18354..18803
                     /locus_tag="VXD01_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEV0601584.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVVPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            18790..19350
                     /locus_tag="VXD01_001173"
     CDS             18790..19350
                     /locus_tag="VXD01_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0601585.1"
                     /translation="MARTELPDKIETECLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYAFLKSEWEVI"
     gene            19350..19928
                     /locus_tag="VXD01_001174"
     CDS             19350..19928
                     /locus_tag="VXD01_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0601586.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAETLQLNSQHQPNELNH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            19921..22572
                     /locus_tag="VXD01_001175"
     CDS             19921..22572
                     /locus_tag="VXD01_001175"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV0601587.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVVHDNVTKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ECDKQADYQAKYDATVARIDEMKKLVK"
     gene            22653..22817
                     /locus_tag="VXD01_001176"
     CDS             22653..22817
                     /locus_tag="VXD01_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV0601588.1"
                     /translation="MGKIVAIDLFSGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDME"
     gene            22868..24247
                     /locus_tag="VXD01_001177"
     CDS             22868..24247
                     /locus_tag="VXD01_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0601589.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNVKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFPRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWLDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTP"
     gene            24850..25653
                     /locus_tag="VXD01_001178"
     CDS             24850..25653
                     /locus_tag="VXD01_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV0601590.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATVYHHTVDASTEEADLVSLRIVELLSRRGFRFSPATLIAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(25769..26871)
                     /locus_tag="VXD01_001179"
                     /pseudo
     CDS             complement(25769..26871)
                     /locus_tag="VXD01_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         8278 a         4725 c         5843 g         8025 t
ORIGIN      
        1 tgtaattttt gcaattcaag acgtttcgat gactattcaa gatctggatg aaaaatttta
       61 aaaaacgatg atatactaaa cttgtcaaag ttgcaacaag acaaaaatta aaaataaaaa
      121 aggagtattt gtcatgaata caaaaatgat gtcacaattt tctgttatgg ataatgaaat
      181 gcttgctcgt gttgaaggtg gcggatgcaa ttggggagat tttgccaaag caggtgttgg
      241 aggaggagca gcaagaggtc ttcaactagg cattaaaaca ggaacatggc aaggtgcagc
      301 aactggtgct gcgggtggag ctatacttgg aggtgtagcc tatgcagcaa catgttggtg
      361 gtaattatgg attttaaaag ttttattatt ggtttagtag ttggtatatt tggtccttat
      421 atggataatt taattagaaa aatattttca aaatttccca aaaaggatac agatagtacc
      481 ccctaaaaaa taaatttctc ccctgtattt gctagcttaa tttacagggg agtttcttta
      541 attttgtttc gcctgtcaaa atgatatgtg atagcaggat gaaaagtcta caaacaagtt
      601 ggtatcaata caatataaag aggaaagtat gtttttcatg cttgcttttt taatttttac
      661 aattcaagag gttttgatga ccatttatga tttgagtgat ccaaggtcaa aataagtgct
      721 atactagcag tgtaaatgtt cttgctcaac taagataaat cgcacattta ggaggaaatc
      781 ttatgaagaa aaaaatactg attattttcg ttctgtatct aatcatgtcc atctttctat
      841 atccgcttag ggagagtgct tggtatcagc tattttatac catagcctat gtgattgcag
      901 ttatgatcta ttttgctatc aataaaaaga aaggagaaaa gaaatgaaaa cttttcttgc
      961 taaaaaacgg aacatcttcc ttgcgagatt gttcttaggt cagttgccct tgcttgtttc
     1021 tacttatcta tttctatctc gtcagttttt aaatttttcc gtagttttcc aatttctttt
     1081 agtagttatt aacttggctt ctattttggt tactgtttat ctcactaggg aaatgaggat
     1141 aagagagttt gaagatgatg atttggttag tcctagaacc aatcaactta tgtttatcgg
     1201 cttgacaggt tttatgtcta ttatttgttt gtatagaggt atcacagcag gagaatctta
     1261 tcaacaacta atcgcttata ttggcgctgt tctctgctta atcatcatgc ttctgctcat
     1321 gtggggcttg aagtattata aaaagtagag cttaatgaag tataaaagaa aagggtaagt
     1381 gtttttgcaa tacttaccct tttataatag attccctgcg aaacaaaata tggtatagta
     1441 tattgaaact agaatagtac gcctctactt ctaaaacatt gttagaaatc gatttgactg
     1501 tcctgatcga tttatcctgt tcttatttca ttttactata gttctatgaa ttatgaagca
     1561 agtaaacaac taactgatgc acgatttaag cgtcttgttg gtgttcagcg taccactttt
     1621 gaagagatgt tagctgtatt aaaaacagct tatcaactta aacacgcaaa aggtggacga
     1681 aaacctaaat taagcctaga agaccttctt atggccactc ttcaatatgt gtgagaatac
     1741 cgcacttatg aagaaattgc ggctgatctt ggtattcacg aaagcaactt aatccgtcgg
     1801 agccaatggg ttgaagtaac tcttgttcaa agtggtgtta cgatttcaaa aactcatctt
     1861 agtgctgagg atacggtgat tgtggatgca acagaggtaa aaataaatcg tcctaaaaaa
     1921 atcaactagc caattattct ggtaaaaaga aatttcacgc tatgaaggct caagcgattg
     1981 tcacaagtca agggagaatt gtttctttgg atatcactgt gaactattgc cacgatatga
     2041 agttgttcaa aatgagtcgc agaaatatcg gacaaactgg taaaaccttg gctgacagta
     2101 attatcaagg gctcatgaag atatatcctc aagcacaaac tccacgtaaa tccagcaaac
     2161 tcaaaccgct aacagttaaa gataaagcct ataaccatgc gttatctaag gagagaagca
     2221 aggttgagag catccttgcc aaagtaaaaa cgtttaaaat gttttcaaca acctatcgaa
     2281 atcatcgtaa acgcttcgga ttacgaatga atttgattgc tggcattatc aatcatgaac
     2341 taggattcta gttttgcagg aagtctaatg taatttttgc aattcaagac gtttcgatga
     2401 ctattcaaga tctggatgaa aaattttaaa aaacgatgat atactaaact tgtcaaagtt
     2461 acaacaagac aaaaattaaa aataaaaaag agtatttgtc atggatacaa aaattatgga
     2521 acaatttcat gaaatggata taactatgtt atctagtatt gaaggaggca agaataattg
     2581 gcaaactaat gtcttagaag gtggtggtgc tgcttttggt ggctgggggc tagggacagc
     2641 tatttgtgct gcgagtggtg ttggagcacc atttatggga gcatgtggat acataggagc
     2701 taaatttggt gtggatcttt gggcaggagt aacaggggca acgggtggat tttaataaaa
     2761 ggagacttgt atgaatactt attgtaatat aaatgaaaca atgctgagtg aggtttatgg
     2821 aggtaattcc ggaggagcag ctgtagttgc tgctttaggt tgtgcagcgg gtggagtgaa
     2881 atatgggaga cttctaggac catggggcgc tgcaatagga ggaattggag gagcagtggt
     2941 ttgtggatat ttagcctata ccgctacatc ataaaaatga aagctaaatt ttatgaaggc
     3001 tatattcttt attattctct tcgcttttca aacctatctt atttatctat ccataagtat
     3061 ctccgataaa aaacaaaaga ctattgaatt aacatcattg aattgttttg tcatattatt
     3121 tctaatctat gataaattaa tttttctctt tattgcctat gtttttttga taatttttat
     3181 attaaacttg ttccgtaact gaaaagtgat atactatatg gatacaaaaa tgatgtcaca
     3241 atttgcagtt atggataatg aaatgcttgc ttgcgttgaa ggtggagata ttgattgggg
     3301 aagaaaaatt agttgtacag caggggttgc atatggcgca attgatgggt gtgcaacaac
     3361 ggtttgacat ttctattggg accatttgct ataggaatag gtgtaactgg tgctgcaggt
     3421 ggagctatac ttggaggtgt agcctatgca gcaatatgtt ggtggtaatt atggatttta
     3481 aaagttttat tattggttta gtagttggta tatttggtcc ttatatggat gacttaatta
     3541 gaaaaatatt ttcaaaatct tccaaaaagg atacggatag tactctctaa aaaataaatt
     3601 tctcccctgt atttgctagc ttaatttaca ggggagtttc tttaatattg tttcgcctgt
     3661 caaaatgata tgtgatagca ggatgaaaag tctacaaaca agttggtatc aatacaatat
     3721 aaagaggaaa gtatgttttt aatgcttact ttttaaattt tttaacaatt caagatgttt
     3781 cgatgacaat tcaagatttg gatgaaaaat tttaaaaaac aatgatatac taaacttgtc
     3841 aaagttgcaa cgggtgctgc tacattatgt taaaaatcgc tcttgattga taagctggat
     3901 ttgttaggaa aggagtaaat aattatggat aagaaaaaga tagtttcgac tataatatgt
     3961 atagtatttc ttgtagtgtc agtagataat ttttttagag acttaacccc gttactgttc
     4021 attttaaata ttattggcct gtcttgcttt tcagtgctaa catacattaa cataaaagag
     4081 atactcttaa atataagtaa atgatgattt ggttagtcct agaaccaatc aacttatgtt
     4141 tatcggcttg gcagatttta tgtttgtcat ttgtttgtat agaggtattt cagaaacaga
     4201 attctatcaa caactaatcg cttatatagg tgtattctct gcttgtttat cacgcttctg
     4261 ctcatgtggg gcttgaagta ttataaaaag tagctttcta tccttttctg acaggatatt
     4321 tgagtagaag gctctattaa attgttagtg aaataaatga atggaggtat ttaatatgaa
     4381 atacagatta ttttttgtta ttttcttgag tagtgtgttg gatattcttt tagggacatt
     4441 tttacaaatc tctatcgtat ctattgggtg gcttgttttt tacagtggtt tgtttgaagc
     4501 aggagttttc cttcttgcta ataaaggggt ggcggtaaaa atcaaggaag tagatattcg
     4561 aaatcgcttt aaatttattt ttggaaaaac cttatggttt caaattcttt tgctcatctt
     4621 tttgataatc aaactttatc ttggtttgga tgcgaggttg attttattct atggacatat
     4681 tttcattgtc tttaatgcct taatgtatct attatctagt agtcaggtta gccttaaaaa
     4741 aaacaaactg tcttcttaat cttacagcag tagagcctga caaggtgagg tcatagtagg
     4801 gaggatttct atgaaaaagt atcagcttct attcaaaaca agtgcaattt tatcctacct
     4861 atttttcgta tttggtcttt ctcagctgac gcttatcgtc caaaactatt ggcaattttc
     4921 ttctcagata ggcaatttat tctggattca aaatatcttg agtttacttt ttattggagt
     4981 catgattgtg gttcttgtta agacaggcca tggttatctc ttccgcattc caagaaaaaa
     5041 atggctttgg tattcgattt tgacagtatt agtggtagtg ttccagatct cttttaacgt
     5101 tcagacagct aaacatgttc agtcaactgc ggaaggttgg gctgtattga ttggttatag
     5161 tgggactaac tttgcagagc taggtattta tatagccctg ttctttctgg ttccactgat
     5221 ggaagaattg atttatagag gactactgca acatgctttc tttaagcatt cgcgatttgg
     5281 tcttgatttg cttcttcctt ctattttatt tgctctccct catttttcaa gcctgcctag
     5341 tctgttagat atcttcgtct ttgcaacagt tggaatcatc tttgctggtt tgacccgcta
     5401 taccaagagc atttatccat cctatgcggt gcatgtgatc aataatattg tagcgacctt
     5461 cccgtttttg ctcacttttc tacatagggt cttggggtaa aaaaacaaaa ggcttgcttt
     5521 tcagccatag aggaggtcat catgtataaa cacttatttt tcctagattc caaaacttta
     5581 gatcggttga caccctatat tctagtcttg gcttctgaca ccattgcttt taatgttttt
     5641 gtgctaacct ttgtatctgc ggtggttttt aatttcctaa attccatgct agctttaatg
     5701 gctatattca taggggctgg ctatgtggtc ggattttggt tactaatact caatgaaaat
     5761 caaagagcaa actaggaaac tagccgcagg ctgtacttga gtacggcaag gcgacgttga
     5821 cgtggtttga atttgatttt cgaagagtat aaaatggttt gttttggaaa ggctagaact
     5881 aaagaatgac gtgtaggaag tctgtttgtt gaggaggata attttatgga gttttttgat
     5941 aaatttcatg ccttgtgttt tggattttta gtactaataa ttgtcattac agttccttat
     6001 acgattaacc atgggggttt ttttcaaaat gaatctgcat tgattcttgt aagtcttctt
     6061 gtaacctcgc tgagtgttgc ttatgctaga aagtttgaaa tgatttcttt tgggatgtta
     6121 agcaagaaac aacttttgct tttcattgca atctttcttc taagtgtact tgagacgctg
     6181 gtttatattc atttcttcgc tgtttcttct ggctcagggg tccaacactt ggcggaagtc
     6241 agcagaggaa tttccctgtc tttgatttta actacctcag tttttggtcc catccaggag
     6301 gaactcattt tcagaggact tcttcaaggt gcggtttttg acaattcttg gttagggctt
     6361 gtgctaactt cctctctctt ttctttcatg catggacctt ctaatgtccc ttcgtttatt
     6421 ttttatctac ttgggggttt gttgctgggc tttgcttata aaaagagtca aaacctatgg
     6481 gtttctactc tagtccatat gctttacaac agttggccac tcttatatta tttataaaaa
     6541 ttatgaaaag gtaagcagaa gacggtgctt acctttttca agctataatg atacccaagc
     6601 caatccagag gcttttcttt gagaatcggg ttagagtggt tgacgaatag gccaaaaact
     6661 agtagaatag taaggaaact ttatacggag gaaagaaatg gatttgggtg ataatgagct
     6721 aacactgact cccatacctg ggaaaagtgg caaggcttat atgggtagct atcctgatgg
     6781 gaagcgcatc tttgtaaaaa tgaacacctc tccaatccta cctggtctag ctagagaaca
     6841 aattgctcca caattattat ggagtcgtcg tttggcagat gggcgtgata tgtgtgctca
     6901 agaatggttg acaggcaaga tattgacccc ctatgatatg aatcgtaagc aaatcgtcaa
     6961 tattttaacc cgtcttcatc gctcacgtcc gttgatgaca caattgagtc gtttgggcta
     7021 tgccatggaa acacctgtag atttactaca gtcttggcag gaaacggctc cagatgcttt
     7081 gcgtaaaaat cattttatca gtgaagtgat ggctgattta cgtcagacta ttccaggatt
     7141 tagagaggac catgcgacca ttgtccatgg agatgtacga catagtaatt ggattgagac
     7201 agatagtggc ttgatttatt tagtagattg ggattcggtt cgcttgaccg atcgcatgtt
     7261 tgatgtggcc catatgctct gccattatat ttcagaacat cagtggaagg aatggttgac
     7321 ctactacggt tacaagtaca atcaaacggt attaagtaaa ttgtattggt atggtcaatt
     7381 gtcttatttg agtcagattt ccaagtatta tatgaaccaa gatttagaaa atgtcaatcg
     7441 ggagattcat ggtttgcgtc atttccgaga caagtatgga aagagaagat gagagttaga
     7501 aatcgtaaag gggcaacaga attactagag gcaaatcccc agtatgtggt cctcaatccc
     7561 ttggaagcca aggcaaaatg gcgggacttg tttggcaatg ataatcccat tcatgtggaa
     7621 gttggaagtg gaaagggtgc ctttgtttca ggtatggcca agcaaaaccc tgacatcaac
     7681 tatatcggga ttgatattca aaagtctgtt ttgagctacg ctttggacaa ggtgcttgaa
     7741 gctggagtgt ctaacatcaa gctcttgtgg gtagatggtt ctgacttgac tgactatttt
     7801 gaagacggtg agattgatcg cttgtatctg aacttttcag atccttggcc taaaaaacgc
     7861 catgaaaagc gtcgtttgac ttacaagacc ttcttggata ccttcaagcg tatcttgcct
     7921 gaaaatggag aaattcattt caagacggat aaccgtggct tgtttgagta tagcctagtg
     7981 agcttttctc aatatggcat gaaactcaat ggtgtctggc tagatttgca tgccagtgat
     8041 tttgaaggca atgtcatgac agaatacgag caaaaattct ccaacaaggg gcaagttatc
     8101 taccgagttg aggcagaatt ttaagaaata gcctgaaatc aggctgtata agtgcttttg
     8161 ctttacataa gttagcaaat gtgctatact aagggtaaga atatgagaaa gagaggcggg
     8221 gaaatatctt cgcctcttgc ttatgaggag gtggacgcaa tcgcaacaat cgtagaatta
     8281 gtcagagaag ttgtagaacc tgtcatagaa gctcctttcg aactcgtgga tatcgagtat
     8341 ggaaagattg gcagtgacat gattctcagt atttttgtag ataaacctga aggaattacc
     8401 ttgaacgaca cggcagactt gacagaaatg atcagtcctg tcctagacac catcaagcca
     8461 gatcccttcc cagaacaata tttcctagaa attaccagtc caggcttgga acgtcctttg
     8521 aaaaccaagg atgccgtcgc tggagcggtt gggaaataca tccatgtcgg gctctaccaa
     8581 gccatcgata agcaaaaggt ctttgaagga accttgttgg ccttcgaaga ggacgagttg
     8641 actatggaat atatggacaa gacacgtaag aaaactgtcc aaattccata tagtttagta
     8701 tcaaaagcac gtttagcagt taaattatag aaaaagaaag gatagctttt gaggattcaa
     8761 aagtgaagaa aacatgagta aagaaatgct agaggccttc cgcattttgg aagaagacaa
     8821 gggaatcaaa aaagaagaca tcatcgacgc agtagtagag tcgcttcgtt ccgcttatcg
     8881 cagacgctat ggtcagtcag acagcgtagc tattgacttc aacgaaaaaa caggtgactt
     8941 tacagtttat actgtccgtg aagttgttga tgaagtattt gatagccgtt tggaaatcag
     9001 cttgaaagat gctcttgcca ttaattcagc ttatgaactt ggagacaaaa tcaagtttga
     9061 agaagcacca gctgagtttg gtcgtgtagc agcccaatct gccaaacaaa ccatcatgga
     9121 aaaaatgcgc aagcaaacac gtgccatcac ttacaatact tacaaagaac atgagcaaga
     9181 aatcatgtct ggtacagtag aacgctttga caaccgcttt atctatgtca accttggtag
     9241 catcgaagcc caattgtcaa aacaagacca aattcctgga gaagtttttg cttctcatga
     9301 tcgtatcgaa gtttatgttt acaaggttga agacaaccct cgtggtgtga acgtctttgt
     9361 tagccgtagc catccagaaa tgatcaaacg tttgatggag caagaaattc cagaagttta
     9421 tgatggaact gttgaaatca tgagcgtggc tcgtgaagca ggtgaccgta cgaaggttgc
     9481 tgttcgtagc cacaatccaa acgtggatgc tatcggtaca atcgttggac gtggtggtgc
     9541 taatatcaag aagattacta gcaaattcca cccagctcgt tacgatgcta aaaatgatcg
     9601 catggtacca atcgaagaaa atatcgatgt tatcgagtgg gtagcagatc cagctgaatt
     9661 tatctacaat gccatcgctc ctgctgaggt tgaccaagtt atctttgatg aaaacgacag
     9721 caaacgtgcc ttggtggttg ttccagataa caagctttct cttgccattg gtcgtcgtgg
     9781 acaaaacgtg cgcttggcgg ctcacttgac tggttaccgt atcgatatca agtctgctag
     9841 cgaatttgaa gccatggaag acgctgcttc agtagagttg gaagtagaaa acgatactgt
     9901 agaagaataa aagctgctag aggagggaaa gatgaaaaca agaaaaatcc ctttgcgcaa
     9961 gtctgttgtg tctaacgaag tgattgataa gcgtgatttg ctccgcattg tcaagaacaa
    10021 ggaaggacaa gtctttattg atcctacggg caaggccaat ggccgcggcg cttatatcaa
    10081 actagacaat gcagaagccc tagaggcgaa aaagaagaag gtctttaacc gcagttttag
    10141 catggaagtg gaagaaagct tttatgacga gttgatcgct tatgtggatc acaaagtgaa
    10201 aagaagagag ttgggacttg aataagcaaa agataagtaa tctcttgggg cttgctcagc
    10261 gagcagggcg catcatatcg ggtgaagaat tggtggtcaa ggccattcaa gacggcaagg
    10321 ccaagttggt ctttctagct catgatgctg gacccaatct gaccaagaag attcaagata
    10381 aaagtcatta ttatcaagta gaaattgtaa ccgtgttttc aacactggaa ttaagcatag
    10441 cagtcgggaa atcgagaaag gttttggctg taacagatgc tggatttaca aagaaaatga
    10501 ggtctcttat ggaatagaag aggaggacat gatttgtcta agaaaagatt gtacgaaatc
    10561 gcaaaagaac ttggaaaaga aagtaaagaa gttgtagcgc gtgcaaaaga gttgggcttg
    10621 gatgtgaaaa gccactcatc aagtgtggaa gaagctgtcg ctgcaaaaat tgctgccagc
    10681 tttaagcctg cagctgctcc gaaagtagaa gcaaaacctg cagcaccaaa agtaagtgca
    10741 gaaaagaaag ccgaaaaatc tgagccagct aaaccagctg tagctaagga agaggcaaaa
    10801 ccggctgagc cagttgctcc gaaaacagaa aaagtagcag cgaaaccgca aagccgtaat
    10861 ttcaaggctg agcgtgaagc ccgtgctaaa gagcaggcag aacgacgcaa gcaaaataag
    10921 ggcaataacc gtgaccaaca acaaaacgga aaccgtcaga aaaacgacgg ccgtaatggt
    10981 ggaaaacaag gtcaaagcaa ccgcgacaat cgtcgcttta atgaccaagc taagaagcag
    11041 caaggtcagc aaaaacgtag aaatgagcgc cgtcagcaag aggacaaacg ttcaaatcaa
    11101 gtggctccac gtattgactt taaagcccgt gcagcagccc taaaagcaga gcaaaatgca
    11161 gagtacgctc gttcaagtga ggaacgcttc aagcagtatc aggctgctaa agaagccttg
    11221 gctcaagcta acaaacgcaa ggaaccagag gaaatctttg aagaagcggc taagttagct
    11281 gaacaagcac agcaagttca agcagtggtt gaagtcgtcc ctgagaaaaa agaacctgca
    11341 gtggatacac gtcgtaaaaa acaagctcga ccagacaaaa atcgtgacga ttatgatcat
    11401 gaagaagatg gtcctagaaa acaacaaaag aatcgaagta gtcaaaatca agtgagaaat
    11461 caaaagaata gtaactggaa taacaacaaa aagaacaaaa aaggcaataa caagaacaac
    11521 cgtaatcaga ctccaaaacc tgttacggag cgtaaattcc atgaattgcc aacagaattt
    11581 gaatatacag atggtatgac cgttgcggaa atcgcaaaac gtatcaaacg tgaaccagct
    11641 gaaatcgtta agaaactttt catgatgggt gtcatggcca cacaaaacca atccttagat
    11701 ggggaaacaa ttgaactcct catggtggat tacggtatcg aagccaaaca aaaggttgaa
    11761 gtggataatg ctgacatcga acgtttcttt gtcgaagatg gttatctcaa tgaagatgaa
    11821 ttggttgagc gtccaccagt tgttactatc atgggacatg ttgaccacgg taaaacaacc
    11881 cttttggata ctcttcgtaa ctcacgtgtt gcgacaggtg aagcaggtgg tattactcag
    11941 catatcggtg cctaccaaat cgtggaaaat ggtaagaaga ttaccttcct tgatacacca
    12001 ggacacgcgg cctttacatc aatgcgtgcg cgtggtgctt ctgttaccga tattacgatc
    12061 ttggtcgtag cggcagatga cggggttatg cctcagacta ttgaagccat caaccactca
    12121 aaagcagcta acgttccaat catcgtagcc attaacaaga ttgataaacc aggtgctaac
    12181 ccagaacgcg ttatcggtga attggcagag catggtgtga tgtcaaccgc ttggggtgga
    12241 gattctgaat ttgttgaaat ctcggctaaa ttcaaccaaa atatcgaaga attgttggaa
    12301 acagtccttc ttgtggctga aatccaagaa ctcaaggcag acccaacagt tcgtgcgatc
    12361 ggtacggtta tcgaagcgcg cttggataaa ggaaaaggtg cggtcgcaac ccttcttgta
    12421 caacaaggta ccttgaatgt tcaagaccca atcgttgtcg gaaatacctt cggtcgtgtc
    12481 cgtgctatga ccaacgacct tggtcgtcgt gttaaagttg ctggaccatc aacaccagtc
    12541 tctatcacag gtttgaacga agcaccgatg gcgggtgacc actttgccgt ttacgaggat
    12601 gaaaaatctg cgcgtgcagc aggtgaagaa cgtgccaaac gtgccctcat gaaacaacgt
    12661 caagctaccc aacgtgttag ccttgaaaac ctctttgata cccttaaagc tggggaactc
    12721 aaatctgtta atgttatcat caaggctgat gtacaaggtt ctgttgaagc cctttctgcc
    12781 tcacttcaaa agattgacgt ggaaggtgtc aaagtgacta tcgtccactc agcggtcggt
    12841 gctatcaacg aatcagacgt gacccttgcc gaagcttcaa atgcctttat cgttggtttc
    12901 aacgtacgcc ctacaccaca agctcgtcaa caagcagaag ctgacgatgt ggaaatccgt
    12961 cttcacagca ttatctacaa ggttatcgaa gagatggaag aagctatgaa agggatgctt
    13021 gatccagaat ttgaagaaaa agttattggt gaagcggtta tccgtgaaac cttcaaggtg
    13081 tctaaagtgg gaactatcgg tggatttatg gttatcaacg gtaaggttgc ccgtgactct
    13141 aaagtccgtg ttatccgtga tggtgtcgtt atctatgatg gtgaactcgc aagcttgaaa
    13201 cactataaag acgacgttaa ggaagttaca aacggccgtg aaggtggatt gatgatcgac
    13261 ggctacaatg atattaagat ggatgatgtg attgaggcgt atgtcatgga agaaatcaag
    13321 agataagatt ttttgctcct ttcttaggtg gtgagggacg caagcaaacc gatggtttca
    13381 ttgcttattt ttgagcctag ggtctcaaaa atcccctgtg atgggactga taaatcagtt
    13441 ccatcacttt caccacggcg aaagaagcag atgacttcaa attgaacttc gtttcaattt
    13501 aaactgaaaa tcaagaagtt taaaatagct aggtctgctg gcctagcttt tggttcaaag
    13561 tagagaaagg aatatcatgg taaatcattt ccgtatagat cgtgtgggca tggaaatcaa
    13621 gcgtgaagtc aatgagattt tgcaaaagaa agtccgtgat ccacgtgtcc aaggtgtgac
    13681 catcacagat gttcagatgc tgggtgactt gtctgttgcc aaggtttatt acaccatttt
    13741 gagtaacctt gcttcggata accaaaaagc ccaaatcggg cttgaaaaag caactggtac
    13801 catcaaacgt gaacttggtc gcaatttgaa attgtacaaa atcccagatt tgaccttcgt
    13861 caaagacgag tccatcgagt atggaaacaa gattgacgag atgctacgca atctggataa
    13921 gaactaaaga agaggggttg cccctctttt ttggtggagg aaaataggtt gaatttgaaa
    13981 tggaaaaata ttcttttata atagattgaa actagaatag tacgcctcta cttctaaaac
    14041 attgttagaa atcgatttga ctgtcctgat cgatttgtcc tgttcttgtt tcgttttaat
    14101 ataaaaaagg gattctgtat tttttaatgt tatctaatta gaaaatgctt tttttgtagg
    14161 aaatataata tgataaggtg caaaaaagaa ataaggagtt tgtatatggc tgaacaagac
    14221 ttagctatgc aagtattgca acaagtggtg aaactacctg ttgttaaggt tgatcgttcg
    14281 aaatttttag tggataagtt ttccaaagaa ttgggtccac aggacattcc taccttattg
    14341 gaacaaggtc caacgtctct cttatctcaa gaaatcttag atcgagtggc taatgcctgt
    14401 attagggata atgttttatt agcgagtggg acttctgttt tggcaggatt acctggaggg
    14461 cttgctatgg caattaccat tccagctgat gtggctcaat tttatggttt ctctctgaaa
    14521 ttggcccaag aattaggtta tatttatggt tatgaggatc tttgggcttc acgcgatgag
    14581 ttgagtgaag atgctcaaaa tacccttttg ctttatctag gcgtcatgtt gggggtgaat
    14641 ggaactgctg ctttgctacg tgctggtggt ataacaattg ccaaacaggt aatgaaaaca
    14701 gtacctaata aagctttaac aaagacgctt tggtatccta ttttgaaaaa agtcttaaga
    14761 atatttggtg tgaatcttac caagggaggg ctggccaaag gaatggggaa atttattcct
    14821 atcttgggtg gtatcatttc aggtggttta acctttgcaa ctatgaaacc gatgggtgaa
    14881 agcttgcaga aagaattgtc caagctagtt aactatagtg aagttcaata tcaagaagat
    14941 gttgaaacaa tccgaaaaga ggctgaaatc atcgaaggag agtaatatgg gactcataaa
    15001 aactctagct aaaatttatg gtaattactt tttgaccgtg caaggtgtaa aagtaatgaa
    15061 aacgataaag aaagatgata atgccgttgt cggtctgggg aaacttttta ttgccgacaa
    15121 gttaatggat acggctcggt ggctcattaa gccagaggat aaaaaatgaa atttttctgg
    15181 ggacttcttg ccattatttt tatcaaaccg attattggga ttgtgaaatt cttttggatg
    15241 atcatctctt ttgcagtcca attgctgttt tacaagatat tggattggtt ctttaaactt
    15301 atctagatgg taatccaagt cgcagagaac tagcaggaac tccactgcta gttttttatt
    15361 ctctttccat atggtataat ataagcagta aaatcatttt atactcttcg aaaatctctt
    15421 caaaccacgt cagcttcacc ttgctgtagg tatggttact gacttcgtca gttctatcca
    15481 caacctcaaa acggtgtttt gagctgactt cgtcagttct atctacaacc tcaaaacact
    15541 gttttgagca acctgcggct agcttcctag tttgctcttt gattttcatt gagtattaga
    15601 acatacaatg gaggtcgtca tggacaatat catcgatgtg tcaattcctg ttgcagaagt
    15661 ggtggacaag catccagaag tcttggaaat tctagtggag ttgggtttta aaccccttgc
    15721 caatccctta atgcgcaata cagttggtcg taaagtatca cttaaacagg gttctaagct
    15781 agcaggaact cctatggaca agattgtacg cacactggaa gcgaatggct acgaagtgat
    15841 tggattagac taatgacaga tgaacggatt catatcctac gggatatttt gttagaattg
    15901 cacaatggcg cctctcctga gtcggttcaa gatcgctttg atgcgacctt tacgggcgtg
    15961 tcagccatcg agatttccct tatggagcac gagctgatga actcggattc gggcgtcact
    16021 tttgaagatg ttatggaact ctgtgatgtc catgccaatc tttttaaaaa tgctatcaaa
    16081 ggtgtcgaag ttttagatac cgaacaccct gggcacccag ttcgtgtctt taaggaagaa
    16141 aatttggccc tccgtgcagc tttgattcgc attcgtagat tgttagatac ctatgagttg
    16201 atggaagacg aggaaatgct tgcggagatg cgcaagggct tggtgcgtca gatgggactt
    16261 gtggggcaat ttgacatcca ttaccaacgt aaagaagaac tcttctttcc tatcatggag
    16321 cgctatggac acgattcacc tcccaaagtt atgtggggag tggatgatca gattagggaa
    16381 ctctttcaaa cagctctaac gacagccaag tcactaccag aagtgtcaat tagcagtgta
    16441 aaggaagctt ttgaagcttt tgcgacagag tttgaaagta tgattttcaa ggaagagtcc
    16501 atcctcctca tgattctcct tgagtctttt actcaggatg actggcttca gattgcggag
    16561 gagagcgatg cctatggcta tgccatcatc cgtccgtcag agaaatgggt gccagaacga
    16621 cagagcttta ttgaggaaaa gattgcagag gagcctgtac agctagatac ggcagaaggt
    16681 caagttcaac aagtcataga tacgccagaa ggccatttta ccattacctt tacccctaag
    16741 gaaaaggaag ctgtgctgga ccgccatagt caacaggctt ttggtaatgg ctatctttca
    16801 gtcgagcagg ccaatctcat cctcaatcac ctccctatgg agattacctt tgtcaataaa
    16861 gatgatattt tccagtatta caatgacaat acgccagctg atgagatgat tttcaaacgg
    16921 acgccgtctc aagtcgggcg caatgtcgaa ctctgccatc cgcctaagta cttggacaag
    16981 gtcaaaacta tcatgaaggg gcttcgtgag ggaagcaaag acaagtatga aatgtggttc
    17041 aagtctgagt cgcgaggtaa gtttgtccac atcacctatg ctgcagtaca cgatgaagac
    17101 ggagaattcc aaggagtgtt ggagtatgtt caggatatcc agccctaccg tgagattgat
    17161 acggactatt ttcgtggatt agaataagga gaaaaaatga gttacgaaca agaatttatg
    17221 aaggaatttg aagcttgggt caatacccaa atcatgatta acgacatggc gcacaaggaa
    17281 agtcaaaaag tttacgaaga agaccaggac gagcgtgcca aagatgccat gattcgctac
    17341 gagagtcgct tggatgctta tcagttcttg cttggtaagt ttgaaaactt caaagcaggc
    17401 aagggattcc atgatttgcc agaaggcttg tttggtgagc gaaattatta aacgagaaag
    17461 attcttgatt tttcactaaa atcttgatag aatgtttatg ttaaatcctt gtcagagcag
    17521 ggatttttta ttgaaaggat tttatcatgt caaagaaact caatcgtaaa aaacaattac
    17581 gaaatggcct ccgtcgcgca ggtgcctttt caagtactgt gactaaggtt gtagatgaga
    17641 caaaaaaagt cgtgaagcgt gcagaacagt cagcaagcgc agctggtaag gctgtttcta
    17701 aaaaagttga acaagcagta gaagctacca aagagcaagc tcaaaaagta gctaattctg
    17761 tagaagattt tgcagcaaac ttgggtggac ttccacttga tcgtgccaag actttctatg
    17821 atgaaggaat caagtctgct tcagatttca aaaactggac tgaaaaagaa ctccttacct
    17881 tgaaaggaat cggcccagct accattaaga aattgaaaga aaatggcatc aagttcaagt
    17941 aatttttttt gagccttgca tttccgagaa aaacttgcta caatagagcc attagaggtg
    18001 ttttgaatcc cacattttac agaaagtggc ggcgctgaga agtccacaaa tgtgtcaaaa
    18061 ctggttgcta atgactgaaa aaatgaaata tttctgtctt tttattttaa agactaaaga
    18121 tgcgggcttg gcccgaaatt gggtggtacc gcggataaac acattcgtcc ctgtcatgta
    18181 gatggcaggg cttttctttt acgtcttagt caaagggggt tgttatgaag caatctttta
    18241 acacaagtaa actatattat ggttttcctg tttttatttt aggatatcaa gattagaatt
    18301 ttggctataa catcacgacc tgtagttcct cttatagtct aggagattgg gttgtgattg
    18361 gagtcgttgc gagagagaat gccgcagagc agatcaaaca gtatcaaaaa tttactgtga
    18421 atatttctga tgaaacttct atgcttgcga tggagcaggc tggttttatc agtcatcagg
    18481 agaaattgga acgtttggga gtgcattatg aaatttctga acgaactcag actcctattt
    18541 tagacgcctg tccacttgtt ttagattgtc gggtagatag gattgttgag gaagacggta
    18601 tttgccacat ctttgccaag attcttgagc gacttgttgt tccagaactc ctggatgaaa
    18661 agggacattt taaaaatcaa ctgtttgccc caacctattt catgggagat ggatatcagc
    18721 gcgtttatcg ctatctggac aagcgtgtag atatgaaggg cagtttcatc aaaaaagcga
    18781 ggaagaagga tggcaagaac tgagctacca gataaaatcg aaacagaatg tctcgtttta
    18841 cgagtccgta ctgtggcgga tgctgaggat atctttgact atgctagttt gccagaggtc
    18901 gcctatccag caggttttcc tccagtcaag accttggaag atgagattta ttatctggag
    18961 cacattcttc cggagcgtaa tcaaaaggaa aatctcccag caggctacgg gattgtcgtc
    19021 aaaggaacgg ataagatcgt tggctctgtc gatttcaacc atcgccatga agatgatgtg
    19081 ctggaaatcg gctatacctt acacccagac tattgggggc gaggttatgt gccagaagct
    19141 gcgcgtgcct tgattgactt agcctttaaa gatttgggtc ttcacaagat tgaactaact
    19201 tgctttggat ataaccttca aagtcaacga gtcgcggaaa aacttggctt taccctcgaa
    19261 gctcgcataa gagaccgcaa agatgctcaa ggcaactgct gtgatgattt gagatatgcc
    19321 tttctgaaga gtgagtggga ggtgatttga tgcatctttt catcattggt gctccagcat
    19381 caggaaaaat gaccattggt caagaattat ctcgactgac ggatgctacc ctcttttata
    19441 accatcaagc cattgatttt gcactagaaa tctatcagga ctatacagag gaaatgtggg
    19501 aatttgttcg tggaatcact ttttcattcc ttggagcgag tgcaagaaat cagcgatcag
    19561 taattttaac agatgtaatt gatttttcaa atcagtatca tctgatatat ttaaagcaaa
    19621 ttcagagttt gttggatgat tatcatcaag agattctttt tgttgagttg gaaacaagtc
    19681 ttgaagagtg catacgtcga aatcgaacgg agaatcgatt aaagtacaaa cccttaaaac
    19741 gacatattga ggtatctgaa agagaaatta tagagaccgc tgaaacactt caattaaatt
    19801 cccaacatca accgaatgag ttgaaccact actttaaaat aaataatacg aatttgtctg
    19861 cagaagaagc tgctaagcaa attcaaaata aaataaacaa aatagagaaa ggacacacac
    19921 atgtctaaag aactttcacc taaatacaat ccagccgagg ttgaggctgg tcgttatcaa
    19981 aaatggcttg atgctgatgt tttcaagcct tcaggcgatc aaaaggctaa gccttattca
    20041 atcgttattc caccaccaaa cgttacaggt aaacttcacc ttggtcacgc ttgggataca
    20101 actttgcaag atattatcat ccgtcaaaaa cgcatgcaag gttttgatac cctttggctt
    20161 ccaggaatgg accacgctgg tattgcgact caggctaagg ttgaggagcg cttgcgtggt
    20221 gagggcattt cccgctatga ccttggtcgt gagtctttct tgacgaaagt ctgggaatgg
    20281 aaagacgaat atgccactac catcaaggaa caatggggca agatggggct ctctgtagac
    20341 tattctcgtg agcgtttcac tcttgacgaa ggtttgtcaa aagctgttcg taaggtcttt
    20401 gtggaccttt acaagaaagg ctggatctac cgtggtgagt ttatcatcaa ctgggaccca
    20461 gcagctcgca cagccctttc tgatattgag gtgattcaca aggatgtgga aggtgccttc
    20521 taccacatga attacatgct ggaagatggt tcacgcgccc ttgaagttgc tacaactcgt
    20581 cctgagacta tgtttgggga cgttgcggtt gcggttaatc cagaagaccc gcgctacaag
    20641 gacttgattg gtaaaaacgt catccttcca atcgctaata aactcatccc aatcgttgga
    20701 gatgagcacg cagatcctga gtttggtact ggtgtcgtga aaatcacacc tgcccacgat
    20761 ccaaatgact tcttggttgg ccaacgtcat aacttgccac aagtcaacgt catgaacgac
    20821 gacggaacta tgaatgagct tgcctttgaa ttttcaggca tggatcgttt tgaagctcgt
    20881 aaggcagtcg ttgctaagtt ggaagaaatc ggtgcccttg tcaaaatcga aaaacgtgtc
    20941 cattcagtcg gtcactcaga acggacaggt gtcgtagttg agccacgctt gtctactcaa
    21001 tggttcgtca agatggacca attggctaag aacgccattg ccaaccaaga cacagaggac
    21061 aaggtcgaat tctacccacc tcgtttcaac gataccttcc ttcaatggat ggaaaatgtc
    21121 cacgactggg ttatctctcg tcagctttgg tggggtcacc aaatccctgc ctggtacaat
    21181 gctgatggtg aaatgtatgt cggcgaagaa gctccagaag gtgacggatg gactcaggac
    21241 gaagacgtct tggatacttg gttcagttct gccctctggc cattttcaac catgggctgg
    21301 cctgaagtcg actcagaaga ctttaaacgt tatttcccaa cttcaacctt ggtaacaggt
    21361 tacgacatca tcttcttctg ggtgtctcgt atgatcttcc agtcattgga attcacaggc
    21421 cgtcaaccat tccaaaacgt ccttatccac ggtcttattc gtgacgagca aggacgcaag
    21481 atgtctaagt ctctcggtaa cgggattgac ccaatggatg ttatcgagaa atacggtgcc
    21541 gatgcccttc gatggttcct ttcaaacggt tctgcgccag gacaagacgt gcgtttctct
    21601 tatgagaaaa tggatgcttc atggaacttc attaacaaga tctggaacat ctctcgctac
    21661 atccttatga acaatgaagg tttgacgctg gatgtggtgc atgacaatgt cacaaaagtt
    21721 gcaacaggtg aggctggtaa tgtgacggac cgctggattc tccacaacct caatgaaacg
    21781 attggaaaag caactgctaa ctttgataag tttgagtttg gtgttgctgg ccacatcctc
    21841 tacaacttca tttgggaaga atttgccaac tggtatgttg agttgaccaa ggaagttctt
    21901 tacagcgaca atgaagacga taaggtcatt actcgatctg ttctcctcta tacgctggat
    21961 aaaatcctcc gtcttcttca cccaatcatg ccattcgtga cagaagaaat ctttggtcag
    22021 tacgctgaag gctctatcgt gacagcagca tacccaactg tcaacccagc ctttgaggac
    22081 cttgctgccc acactggtgt ggaaagtctc aaagacttga tccgtgccgt tcgtaatgcg
    22141 cgtgcggaag taaatgtagc accaagcaaa cctatcacca tccttgttaa gacaagcgat
    22201 agcgacttgg aagccttctt taacagcaat gtcaactaca tcaaacgctt tacaaatcca
    22261 gaacatttgg aaatcgcatc aaccatccct gcacctgaac tggctatgtc aagtgtcatc
    22321 acaggagcag aaatctacct gccactggcc gatctcctca atgttgaaga agaactggcc
    22381 cgtctcgaca aggaacttgc taaatggcaa aaagaactgg acatggttgg taagaaactc
    22441 tctaacgaac gcttcgtagc caacgccaaa ccagaagtcg tccaaaaaga atgcgacaaa
    22501 caagctgact accaagctaa atatgacgcg accgtcgcac gtattgatga gatgaagaag
    22561 ttggtgaaat gatgttaaaa acctaaccct ctcgggttgg gttttacatt tgataatgtt
    22621 ataataaaaa ggagaaactt taggagaata ctatggggaa aattgttgct attgatttat
    22681 ttagcggtgc aggtggcact acaagtggcc ttaaaaaatc aggcatagat gttcaagttg
    22741 ctgttgaaat tgattccgta gctgttaaaa cttataagtt aaataatcct gaggtgtctg
    22801 taatagatat ggagtaaata aaacttcaat tttacaagct ttatatggtt ctccagccaa
    22861 taaaagtgtg tctgaatatt ggtttagtac aaatgttgat caaatagatg aagtggatgg
    22921 gaaacaatgt ttaatctatt catattataa cgttaaagct tctagaaatg tagaagttct
    22981 taaaggccgt tctggaacaa aaaaaggatt agattattgg gaaccatatg ctcctcaaaa
    23041 acaatatgag atggaaagat tacccaaaaa taaatatatt ggaagttctt cgacagacag
    23101 atgggatggc attgaaaaaa atgttgtctt ttgtgattgt aaagaatatg tttctgcttt
    23161 tgatttattt ttctatcact ataattttaa aaaaatttct actcaacgta gtaaacaaga
    23221 ttttataaga ttacgatcta aaccagttgc tgatatttta aagaataata caagtagcta
    23281 tacgcgttat aaaaaggaaa tggttataga taatgttaaa gttgatgata aagtttgtga
    23341 aattattagt gaaataatgg atgaatctta tacagacatt caaattttaa cacataagtt
    23401 gtattcaaaa ggtgatgata taaaagcttc caaaactatt tggatgaaaa aatctggaaa
    23461 agaatattct gaggcttttg caggaacagg tgaggctaga attattttgt tagtaaatga
    23521 tatagtaaat gcgcaatcaa attcattaat attaatagat gaacctgaaa tctcacttca
    23581 tccgagtgca atctataaat ttaaagagtt tttacttcaa gagtgtttaa ataaaaaaca
    23641 tcaaattatt atcactacac attctacaca acttataaaa gattttccta gagaagccgt
    23701 gaaactttta gtgaaaaacg gagaaaaggt agatgttatt gaaaatattg attatcagga
    23761 tgcatttttt gaattaggtg atgtgtatca ttctaggaag atgatttatg ttgaagatag
    23821 actagctaaa tatattctag agtttgttat cactcattca ggtagtgaga atcttaaaca
    23881 gaatttagta gtgagatata tccctggtgg agcaaatcaa ataatttgta ataatatttt
    23941 aaactcatcg tatttagatt ccgataacca ttatttttgg cttgatggag atcaaaacac
    24001 taatgttagt gaatcaaata atttaatgaa ctatcttgaa aatggtgttg ttatatcaga
    24061 taaaattcct gaatcagata ataaaaatct tgatgatatt ataaaattga taacgggatg
    24121 tccaattaaa tttaatgttt caggtaataa agggcaaaaa aataatattg aattaattgc
    24181 gaaacaaaga agctttatag attattgggc taaatacgtt tcttatcttc ctttcccaac
    24241 cccatagttt tttttagcta atttatgtaa cagcgtagat agggaaggtt atgatttttc
    24301 taaagatggc aacggaaaag aatattttag aaaaaaattc aagtagcgtt aggaatagag
    24361 aatataactt ctgaagatat tttccaggag caaagaagag ctgtttcaaa aatacagcca
    24421 gaatcatcaa tgtttcagtg tattaaagaa aaattagagg cattgttcta attccttaga
    24481 ttaggtacta cataacaaat ttttaaattc aaacccgcac caaaaacaac attgcaactt
    24541 tcttctcagg taatgtgttg ggatttgaac agaccaacga gttcatagtg gtgtatgcca
    24601 atgactttga taagtctacg cgtcagactt attagttcat ttatccagat atatctcgat
    24661 aatcatatta tttagtcaaa gaacatccca tatgagggca tgaaatgcta agtttagctt
    24721 gctcactatt aagatgaagt atatatattt catagaacct attgtgaagg atttttataa
    24781 ttttcgccaa ttccatacct atttcacaat ttaccgatga cacagaaaaa caattgaaag
    24841 gatatttcta tgcaatcaac ttacaacatt gacaatccaa acttgtctta tgaagcgaag
    24901 cgtgatttat ggcggatagg ttttggtctg cagaaagttg acaatctagt gccatcagcg
    24961 tatatggaat ctttggctga gaaacagtcc cggggtgaac tgacttatga gcaggtttat
    25021 gaggatgcaa cggtttatca tcataccgtt gatgcgagta cggaggaggc agacttggtt
    25081 tctttgcgta tcgtagaact cttgtctcga agaggtttta gattcagtcc tgcgacttta
    25141 attgctattc ataaggagtt gtttcaagat atatttgaac cctctattcc ggtggggcaa
    25201 tttcgtcaga ccaatatcac aaagaatgaa cctgttttga atggtgaaag tgttgtgtac
    25261 tctgattact ccatgattca aatgaccttg gattatgatt ttaatcagga aaaacaagtt
    25321 gcatatgcga cactaactca ggcggatgtg gttaaacaaa tccagcattt tatttcagga
    25381 atctggcaga ttcatccatt tcgcgaagga aacactcgga cagtaacggt ctttttgatt
    25441 cagtatcttc gtgagtttgg ttttgatatt gataatatac catttcagca acattccaag
    25501 tattttcgtg atgccttggt attagataat gcaaagattt tacagcgacg tcctgagttt
    25561 ttaacagctt tttttgaaaa tctcttgctc ggtggtcaaa atgatttgtc ttcagaaaaa
    25621 atgtatctag atttagacct cgatttttca taatccaaat actgagtaaa cattgaattt
    25681 taggcaaaaa tgaagtaaat attctcacaa gaaaacgtat atcatcaaag ttttaggtgt
    25741 actgacccca aaaagttaga caaataattt atccgaagga tttagttctg tattgcacaa
    25801 ggctaagtcc ttttagtttt accttaattc gtttattgtt gtagtaatca atatagtcta
    25861 caatagcttg ttccaattga ttaagtgatt taaatgtttt ctcatagcca taaaacattt
    25921 ccgatttcag aatcccaaag aaggactcca tcataccgtt gtcttggctg tttcccttac
    25981 gtgacatgga tgcttgaatt cccttaccct caagaaactg atgataagaa tcgtgttggt
    26041 attgccagcc ttggtcacta tggagaatcg tattctcgta gtgcttctct gtgaatgcct
    26101 gttccaacat tgtttgtact tgttctaaat taggcgaaca agaaagatta aaagcaataa
    26161 tttcgctgtt aaagccatct aaaactggtg ataagtaaag cttttgagta cttgctggaa
    26221 tggcaaattc tgtcacatct gtatagcact tttccattgt tttagagcct tcaaattggc
    26281 cttgaatgag attctctgcc ttcttgccaa cgtctccttt atgagaagaa tattttcgtt
    26341 tctgtcgcat tttagcttgt aaattgagta ctttcatcaa gccttgaact cttttatgat
    26401 ttaccagata agcacgattt cttagttcta aataaatccg acgataagca taatttccct
    26461 tgtgttcgat aaaaatggat tgaatttcag ctttaagctc ttggtcctta tctgttttgt
    26521 ctagctgttt caagtgatag tagtaggtcg aacgagctag tttaatggat tttagaagaa
    26581 gaactaacga aaactcagtc attaattctt gaacaatttc tgtctttctt ctttctcttt
    26641 ttcctccttc aatcggagtt ctcttaactt ttttaggatg gcattctccg ctctcaggta
    26701 ctctcccttt tgttttctca acaatagtat acccgttttt cctgtattgt gctagccagt
    26761 taagaagtat cgtacgactt gggaggccgt attcaagaga aactctatct ttagtccagc
    26821 cttcatgtca gactttatga atcatttctt gttttaaatc aggagaatag t
//
LOCUS       DAVLDI010000027        26793 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLDI010000027 DAVLDI010000000
VERSION     DAVLDI010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26793
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.027"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..193
                     /locus_tag="VXD01_001180"
     CDS             <1..193
                     /locus_tag="VXD01_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0601591.1"
                     /translation="KLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTVLPDIKIKL
                     PIDSRGTPDWNYMERYRDR"
     gene            159..472
                     /locus_tag="VXD01_001181"
                     /pseudo
     CDS             159..472
                     /locus_tag="VXD01_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1156..1317
                     /locus_tag="VXD01_001182"
     CDS             1156..1317
                     /locus_tag="VXD01_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601592.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1409..3088
                     /locus_tag="VXD01_001183"
     CDS             1409..3088
                     /locus_tag="VXD01_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0601593.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEDCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            3356..3922
                     /locus_tag="VXD01_001184"
     CDS             3356..3922
                     /locus_tag="VXD01_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601594.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4244..4432
                     /locus_tag="VXD01_001185"
     CDS             4244..4432
                     /locus_tag="VXD01_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0601595.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4494..5252
                     /locus_tag="VXD01_001186"
     CDS             4494..5252
                     /locus_tag="VXD01_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0601596.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            5310..5771
                     /locus_tag="VXD01_001187"
     CDS             5310..5771
                     /locus_tag="VXD01_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0601597.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRF"
     gene            5805..6164
                     /locus_tag="VXD01_001188"
     CDS             5805..6164
                     /locus_tag="VXD01_001188"
                     /inference="COORDINATES: protein motif:HMM:NF015692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0601598.1"
                     /translation="MNDNPIECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQET
                     VPQAIIAFLESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLD
                     EPLKDVVRRWENRIKVY"
     gene            6276..7160
                     /locus_tag="VXD01_001189"
     CDS             6276..7160
                     /locus_tag="VXD01_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0601599.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKQGILA
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7323..9062
                     /locus_tag="VXD01_001190"
     CDS             7323..9062
                     /locus_tag="VXD01_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV0601600.1"
                     /translation="MELSAIYHRTESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            9337..9639
                     /locus_tag="VXD01_001191"
     CDS             9337..9639
                     /locus_tag="VXD01_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601601.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            9695..10123
                     /locus_tag="VXD01_001192"
     CDS             9695..10123
                     /locus_tag="VXD01_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0601602.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            10181..10790
                     /locus_tag="VXD01_001193"
                     /pseudo
     CDS             10181..10790
                     /locus_tag="VXD01_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662948.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
     gene            11072..11319
                     /locus_tag="VXD01_001194"
                     /pseudo
     CDS             11072..11319
                     /locus_tag="VXD01_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            11424..11726
                     /locus_tag="VXD01_001195"
                     /pseudo
     CDS             11424..11726
                     /locus_tag="VXD01_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            11882..13111
                     /locus_tag="VXD01_001196"
     CDS             11882..13111
                     /locus_tag="VXD01_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV0601603.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            13131..15827
                     /gene="ppc"
                     /locus_tag="VXD01_001197"
     CDS             13131..15827
                     /gene="ppc"
                     /locus_tag="VXD01_001197"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV0601604.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    15910..16127
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            16240..17244
                     /locus_tag="VXD01_001198"
     CDS             16240..17244
                     /locus_tag="VXD01_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0601605.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            17313..18179
                     /locus_tag="VXD01_001199"
     CDS             17313..18179
                     /locus_tag="VXD01_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0601606.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            18176..18934
                     /locus_tag="VXD01_001200"
     CDS             18176..18934
                     /locus_tag="VXD01_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601607.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            19024..20784
                     /gene="dnaG"
                     /locus_tag="VXD01_001201"
     CDS             19024..20784
                     /gene="dnaG"
                     /locus_tag="VXD01_001201"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV0601608.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYQAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEEFERLISQKRRME"
     gene            20787..21896
                     /gene="rpoD"
                     /locus_tag="VXD01_001202"
     CDS             20787..21896
                     /gene="rpoD"
                     /locus_tag="VXD01_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV0601609.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            21910..22239
                     /locus_tag="VXD01_001203"
     CDS             21910..22239
                     /locus_tag="VXD01_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0601610.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            22354..23397
                     /gene="cpoA"
                     /locus_tag="VXD01_001204"
     CDS             22354..23397
                     /gene="cpoA"
                     /locus_tag="VXD01_001204"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV0601611.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            23413..24738
                     /locus_tag="VXD01_001205"
     CDS             23413..24738
                     /locus_tag="VXD01_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV0601612.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRIIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            24769..24945
                     /locus_tag="VXD01_001206"
     CDS             24769..24945
                     /locus_tag="VXD01_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0601613.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            25004..25138
                     /locus_tag="VXD01_001207"
     CDS             25004..25138
                     /locus_tag="VXD01_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV0601614.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            25202..26512
                     /gene="obgE"
                     /locus_tag="VXD01_001208"
     CDS             25202..26512
                     /gene="obgE"
                     /locus_tag="VXD01_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV0601615.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYSRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            26522..26680
                     /locus_tag="VXD01_001209"
     CDS             26522..26680
                     /locus_tag="VXD01_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601616.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT         8814 a         4253 c         5820 g         7906 t
ORIGIN      
        1 aaaattaaaa aataaagaat tgaataaaga agtagcattc tatttaactt caattattag
       61 gcaagcttta aaaaatactg aatataaaga tcaaatatct agcacagtat tgccagatat
      121 caaaattaaa ttaccgatag acagtagagg tactccagat tggaattaca tggaaagata
      181 tagagataga taaagagaga gggagagata gataaaaagt ccacccccat ttttttatgg
      241 agaattcaaa aatgtaaggt taagcaaaga agaatataaa aatctaaaag aaaaattaaa
      301 ctcacacaca gatataatga taaataaact atccagatac atggaaagca gtggtaagac
      361 ctatcaaaac cactatgtga caatcttaaa atggtatgaa gaagataaag acaaactaag
      421 acagaaaggt ttaaataaaa aaatgaatta tgatgtagga gaatctttat agataaaaag
      481 aggtggaaag gcactattaa agactttaag tctaaaaagg tatcaaagta tgccagagat
      541 aaaaaaatat aaatatgaca ctttaaaggt gattagaaaa ttaaagaaat gctagaagac
      601 ttttagatga cagttaccaa gagggtctaa ttttcactgc tacttatgca gtgggaattg
      661 gaccttttta tataagcaaa ttctatttca aaattggtta ccaagaaaga cttcttttca
      721 ctgttaagta taagagggta atttatagaa ttttgttaca ttaagataaa tattttctga
      781 tggtcaaatt ttaaaaagat taataattct cgataaattt tgaaccttaa caattgaata
      841 gaccaagaca agacgttaat tatttttgga gcgtaataac ctatccgtca agatctttcg
      901 gctgaataat tcggcaaaaa aagttctgct aagtaaaaag aaagtgagcg ataagtaaga
      961 gtttgaatat agggagggat accctatccg ctatgaagaa aatgaggata atgatacttc
     1021 taaggttgaa gccggctcat ccggaataga ggcggaggtg agattcctat gttgctaatc
     1081 caaagcactt gtcaatgtca aaaaacttaa ttaaacaaat aattattaga tataaaactt
     1141 tagaggaggt atatattgga caatgactgg aatggattgg ctgatttaat agcaaatctg
     1201 attgcaaaat atgctggtgc tttagattta gataatctac ccgatccaac gccagcaaaa
     1261 aatcaagaga tgaaaaatag ttttgacatg gcaaaaacac aaattgagac ggactaataa
     1321 aagtgttata atatacttga aatgatagtc caaacttaaa ttaaaaaaat tatatatgat
     1381 atagaaaaat tatattgagg ttaatactat gtcaaaagaa aaaataaaag tatacctcta
     1441 tacacgagta tctacgtcaa tacagataga ggggtattcg ttagaggcac aaaaatcacg
     1501 aatgaaagct tttgctattt acaacgatta tgaaattgtt ggagagtatg aagatgccgg
     1561 gaagtctggc aagtctattg aaggtagaat acagttcaat cgaatgatgg aagatataaa
     1621 atctggaaaa gatggagtat cttttgttct tgtgtttaag ttatcaagat ttgcaagaaa
     1681 tgccgctgat gttctttcta cacttcagat aatgcaggat tatggagtta atcttatctg
     1741 cgttgaagat ggcattgatt catctaaaga tgctgggaaa ctaatgattt ctgttttatc
     1801 agctgtggct gaaatagaaa gagaaaacat ccgtattcaa acaatggaag attgcattca
     1861 aaaagcaagg gaaggaaaat ggaatggtgg ctttgctccg tatggatata aacttgaaga
     1921 cggcaagctg tttataaatg aggaagaggc agttgcaata agaacgattt tcgaccagta
     1981 tgtaaatact acgataggag ccaatgggat atctaaatac ttagagaatc atggaattag
     2041 aaaaatccca agacagaatg gtaagaatcc tttgtttgat gcaggtctta taagaaagat
     2101 attaaagaat cctgtatata atgggaaaat agcatttgga agaagaactt tagaaaaagt
     2161 tcatggtaca agaaatgaat ataagcaggt tgaacaagat gaatatctaa tatctgaagg
     2221 gatacatgaa gctatagttt ccgatgaagt ttggcaagct gctcaggtta agctaaaatc
     2281 tcaagcaaag aaatatgagc atgtgaataa aggaaaagat acacgcacac acttgctttc
     2341 tggaattgta aaatgcccga tatgtggagt gggaatgttt gggaacaagt gtatcaagaa
     2401 aaagaaagat ggcacaaagt ataaagattt ttattactat ggttgtaaac ataggcagat
     2461 gataagaggt cataagtgta cattcagtaa gcaaattaga gaagaattgt tagatgatgc
     2521 tgttgcagag gtgattgtca agatagtaag taatccgaaa tttgcttcta tgatgcaaga
     2581 aaaaatcaac atgaaggtgg atacctctga aatagaaaaa gaaatagata attaccaaaa
     2641 ggaattgaga aagagtcatt ctacaaagtt taagctaatt gaggaaatag ataatttaga
     2701 tgttgaagat aagcactata agagaaggaa acaggattta gatgatagac tatatcgtat
     2761 gtatgacaaa atagatgaat tagaatcatc actaattgat gcgaaagcaa agaaacagac
     2821 tattgaagct gaaaaactta caggagataa catatataag gttctgatct attttgataa
     2881 gctctataaa gtcatgaatg atgtagagcg taggcagtta atttcagctt tgatttctga
     2941 aattcaagtt tatgaagaaa aacaatctaa cggacaatgg ctaaaatcca ttacttttaa
     3001 gctaccaatt atagaagaaa atctcaacat agatttggac aatgatgaac aagttgaatg
     3061 tgtaagttta ttagagaaac gtagttaatc ctcaaaaggt tccccaaact ttttgagtcc
     3121 cactgacgca tcacgctgag gcggtatcac tgcttgtacg agttgaagca tcagcgaagt
     3181 aaaagtagat gttcagccaa tgcgacgagg tgagaccgaa ggtcgataag gtgtgttctg
     3241 ggtataggac tcgtaaagta agtaggaaat atgatgagat gatacagaga gcctgaattg
     3301 gtcaggtgac gtgcttattt acattagcct gataatgaaa atggagagat tatcgatggt
     3361 tatattggaa ttgtaccaaa atgattattc taaagattta gtagcatttg attccataga
     3421 agatgggaaa gcctttgtgg ctcaaatccc gggatacact ctggaaacag aagatggttt
     3481 tgaagtggag tattttaatc ctaaaaacat accggattat atggaaatta tttttaacgg
     3541 aaatattgtt cctttatcta aatttatgtt cgatcctgag gaaaatgtaa atattatttg
     3601 gaaagagatt tcaaatttat ccctcaaaaa tgatagagtg atcgaaggat attcaaaaat
     3661 tgatgcatat gtcgttaaca accatgaagt taaagcctat gtcgaaacaa gagaaacgaa
     3721 ctatcgtaaa gcaaaagact tcttagaaag ccgcggatat gaaatcgaca gaagcttttt
     3781 cggaagtgaa gacggtgaag cgattcttta cagaaaaaaa gggatcgaag tttggcattt
     3841 cttgtgtcac ttagacccaa tgtttgtaga gattgaagat gtagaaggat atgttaaaga
     3901 agaagttgga gagattcaat agtcaaccaa agttccttgt gagtatatac ctttgctagt
     3961 aaaagagtca aaacgttata acgaaggggg ggaagaaaac ccttgagtgt aagtcttttt
     4021 cttgtttaga gggaaagtat tagagtagcc gctcataatt tatactagat ttgataactg
     4081 atttgagaca gattttattt ctataaatat tgtgaaaatt ttttaatacc aaagatttaa
     4141 agttactgtg ttaaaaatcc tctccacttt taaactaatg tattataaaa gccagttgac
     4201 acaagtgtta cacctgtgat agaattaact tgaggtgatg aaaatggcaa ccgataaaaa
     4261 tagaataatg attagcttgg atgataaaaa tctagagaaa cttgaaaatt tagtagaaga
     4321 tgctagagat agaaggggaa tgcgactaac aaagtcccag gttattgaat tactcctaaa
     4381 taccgttgat tatttcgatg atattatggg ggctatttac tcaaaaaaat aagagcaaaa
     4441 ttgctattat tttttacaaa ttggtgtaac actagtgata taggagtgat gaaatggttg
     4501 tttatattag acaaagtaaa ttaccaagtg aggtttcaat taataaatac aatgctcaag
     4561 taggtgccta cttacaagga gaagaagctg ttttatatca atctttttct gaaataaaag
     4621 agttaacaag tgaagatata gttgtagatt atataatgga gactagagca ttactaaaaa
     4681 tgatgggctt aaacgttccg gttcatgact atcctattga gcttaaagag ttttatggtc
     4741 gaaagattta tgctggtatt ttaggagaga ttgtgaatat acctgataat tggggaaaat
     4801 ttattaagcc taaagctggt tcaaaagtct ttactggaag agttgttaat ggaacccatg
     4861 atttaatagg tattggtcta cctttcgact atcctatatg gattagtgag gttgtagaat
     4921 tcatagctga atggcgttgt tttgtgttag atggtcgcgt attagatgtt cgaccctata
     4981 caggtgatta tcatgcacaa tttgatgcaa gtgtaattga tgaagcgata tcatgttgga
     5041 aagatgcgcc aatagcttat ggactagata tcggtgttac tcgcgatggc agaacacttg
     5101 ttgttgaagt aaatgatggt tatgcattgg gaaattatgg cctatctcct ttaaaatcaa
     5161 tcaattttca tagagctagg tggaaagaaa tggtaaaacc ctattttgaa aaaaatgaaa
     5221 tttttaaaat ccaacaggat gttgttttct aaaataaata tggtatataa ccaatataaa
     5281 aagcatcaaa atgaacaagg aggaatctga tgcttggagc aattattgga gatattgtcg
     5341 gttctgttta cgaatggaac aatatcaaaa caaaggactt tcctttattt cggaaggact
     5401 gcttttttac agatgacacg gttatgacct gtgctgttgc agaagcaatt atgaatggtg
     5461 gacaaaaaga cgacttcatt gacgcgatga agaaatatgg cagaatgtat ccgaatgctg
     5521 attacggtgc tcggtttaat gcatggctaa acagcgataa ccgtgagcct tataatagct
     5581 ttgggaatgg atcagctatg cgtatttctc catgtgcttg gatcatggac tgtggttttt
     5641 atgcgaaaac tggtatatgg ccatcatcta gaggacttac gagtctttct gcagaggtaa
     5701 ctcataatca tccagaaggt gtcaaaggcg ctatggctac agctgatgct atctttctat
     5761 gtcgttttta atttggtggt tattgtagag agtacgagta atcaattaac gacaatccta
     5821 tagagtgtaa aagacgaatt aaggattata tagaaaaaga atacgattac aatctatctc
     5881 aaactttaga tgaaatccgt cctaactatc gttttaacga aacatgtcag gaaactgtcc
     5941 ctcaagccat tatcgccttt cttgaaagta gagacttcga agatgcgata agaaatgcca
     6001 tctcacttgg tggcgacagt gatactctcg cagcaatcac ttgtagcata gcagaggcag
     6061 cttacggtat tcctgattgg atcaaggata aggcctattc ttacttggat gaacccttaa
     6121 aggatgtagt taggcgatgg gaaaatagaa taaaagtgta ttaatctcca gtacgtcaga
     6181 tttctctttt ctgtattttc attgtataat aggattacat ttacttgcat acgacgaaat
     6241 gtaaacattt ctatttaaaa ttaaggataa aatcaatgaa aaaagcaatg gtaattatca
     6301 accctacttc tggtggcgag aaggctttgg attacaaaga aaagctggag aataaagcaa
     6361 aagaatactt tgaatatgtt gaaaccaaaa ttaccgaaaa agcgctggat gcaacacatt
     6421 ttgctgaaga agcttctcgt gagcagtatg atgcagtggt tgtgtttggt ggagatggga
     6481 ctgtcaatga agtcatttca ggtattgatg agagagacta cattcctaag ttagggatta
     6541 tcccaggcgg tacgggtaac ctcattacaa aacttttgga aatcaatcaa gacatcgatg
     6601 gcgcaattga cgaactggat tttgatttaa ccaataagat tgatatcggt aaagcaaatg
     6661 acaactattt tggttatatc tttagtatcg gttctctgcc tgaggcgatt cacaatgttg
     6721 aaatagagga caaaacaaaa caaggtattt tagcctatgc tgtaaatact atgaagtctg
     6781 tcatgacaga tcaggtcttt aacattaagg ttgagacaga aaatggaaat tatgttggtg
     6841 aagctagcca tgttttggtc cttttgacaa attacttcgc tgataagaaa atctttgaag
     6901 aaaacaagga cggctatgcc aacattttga ttctgaaaga tgcctctata ttctccaaat
     6961 tatccgtcat tcctgattta ttaaaagggg atgttatcgc aaatgataat atcgagtata
     7021 tcaaagcgcg taatattaaa atctcttcag atagtgaatt ggagtcagat gttgacggag
     7081 ataaatcaga taacctacct gtagaaatca aagtcctagc tcagcgagta gaagtatttt
     7141 caaaaccgaa agaggattag tatatagaga aagccttttt taaggctttt tgtatacttt
     7201 aaaagatagt tcctttaaca acggacattc cttgcaaata gttcacaaaa atagtatact
     7261 ggattcattg agtttgaaaa cgtttgcgta aaatttgaat gaatacttta ggagataaat
     7321 tgatggaatt gagtgctatt taccatagga ctgagtcgga gtatgcctat ctttataagg
     7381 ataagaaact ccatattcga attcgaacta agaaagggga cattgaaagc atcaacttgc
     7441 actatgggga cccttttatc tttatggagg agttttatca ggatacaaaa gaaatggtca
     7501 agataacttc tggtacctta tttgaccatt ggcaggttga agtgtcagtt gactttgcac
     7561 gtatccagta tctttttgag ctcagagata cagaaggtca aaatattttg tatggcgata
     7621 aagggtgtgt ggaaaattct ctagaaaatc ttcatgcaat tgggaatgga tttaagttgc
     7681 cttatcttca tgagattgat gcctgcaagg ttcctgactg ggtttcaaat acggtatggt
     7741 atcagatatt tcctgaaaga tttgccaatg gcaatgctct attaaaccca gaagggactt
     7801 tagactggga ttcatctgtc acacctaaga gcgatgattt ctttggtggt gatttacagg
     7861 ggattattga tcatatggat tacttgcaag acttgggtat tactggacta tatctttgtc
     7921 ccatctttga atctacaagc aatcacaagt acaatacgac agattacttt gaaattgacc
     7981 gtcattttgg agacaaggag acctttcggg aactggtgga tcaagcgcat catcgtggca
     8041 tgaaagtcat gctggatgcg gtatttaatc atattggttc gcaatctctt caatggaaaa
     8101 atgtcgtcaa aaatggtgaa cagtctgctt ataaggattg gttccatatt caacaattcc
     8161 cagtgacaac tgaaaagcta gttaataaga gagacttacc ctatcatgtt tttggtttcg
     8221 aggactatat gcctaagcta aatacagcca atccagaggt caagaattat cttttaaagg
     8281 ttgcgactta ttggattgaa gagtttaata tcgatgcttg gcgtttggat gtggctaatg
     8341 agattgacca tcagttctgg aaggattttc gtaaggcagt tttagctaaa aatcctgatc
     8401 tttatatcct aggagaagtc tggcatacat ctcagccttg gctaaatgga gatgagttcc
     8461 atgccgtcat gaattatcct ttatctgata gtatcaagga ctatttctta cgaggaatta
     8521 agaagacaga ccagttcatc gatgaaatca atggagagtc tatgtattac aagcagcaga
     8581 tttcagaggt catgtttaat ctcttggatt cacatgatac agagcgaatc ctgtggacgg
     8641 ccaatgaaga tgttcaactg gttaaatcag ccttagcctt tctcttttta caaaaaggaa
     8701 caccgtgcat ttattacgga accgagctag ccttgactgg aggaccagat ccagattgtc
     8761 gtcgttgtat gccttgggaa cgtgtatcaa gtgacaatga tatgctgaac tttatgaaga
     8821 ggctgattaa gattcggaaa tacgcgtcag taatcatttc gcatggcaag tatagccttc
     8881 aagaaatcaa atctgatcta gtagctctgg aatggaaata cgaaggacgg atcctcaaag
     8941 caatattcaa ccaatcaaca gaagattatc ttttagagaa agaagcagta gcactagcaa
     9001 gcaattgcca agaattggag aatcagcttg tcatctctcc agatggattt gtgattttct
     9061 aaaaactagt tgatgaagat tatggtacat ttcatatctt atatagtata ataaggctag
     9121 ttactaaact tgtaaaggag aacttaaatg aattgtagag gacacgaaac aagacaaaga
     9181 attgttagag attttgaagt ttagcctaaa gcacatatta agctgttagc aaatcaacaa
     9241 aaacatagtg atgcaggagc aactattgaa gatgaatatt atgtatttat cgctgagagt
     9301 aaaattgatg gcaagaagga agttattcag tgttgcatgg gtgcggcaag ggatttttta
     9361 gaactaatta atcacaaagg gctacctctt tttaatccgc ttgtaggtga ttctcatgta
     9421 aataatagac aagaatatga caatacaggg agtggaaatt tacaacctga aaagtggaat
     9481 gaaactgcaa agcagcttta taatgttata atgtggttga ttattttatg gaatgctaag
     9541 ccggatacac ctttatttaa ttttaaagac gaagtaatta agtataaaac atatgagcct
     9601 tttgaaagca gtataaaatt ggtatcaatc aatgagtaac aaagtatcag catgattcga
     9661 aacatttact tgtaatttgc ggaggaacat caatatggat ggaataacaa aagattttat
     9721 aaaaacggct aaactaatga aacaattatg gccccaattg accgataaag aagctattga
     9781 tgaagtaaaa aaatatacga atggcaaaaa tactgcaatc tttactgaag ttgaaggtga
     9841 cacaattgta ggtctagcac tatgttcact cagatttgat tatgttgaag gttgtaaata
     9901 tagtcctgtt ggattcttag aagggattat tgttgacgag gaatatcgtt taaaggatat
     9961 tgctaaaaat ctctgtacaa aatgtgagga atgggcgaaa aataaaggat gtaaggaatt
    10021 tgcaagtgac tgtactttaa cgaatacgga ttctataaga tttcatctca atattggatt
    10081 tcaggaggca aatagaatta ttcattttaa gaaaaaatta taatttagaa acgtgaataa
    10141 acttgtttaa actttatgta tctttagaaa gtgtgttaac ttgaaagaac aaattttttt
    10201 gatgggtggg aatcccccaa tgaagaaata tagtattgtt gataaaattg tattatcaac
    10261 caagattaaa agaattatca tttttacagt ttttcgagaa aattgggaac cgtacatgaa
    10321 aaagtacacg gaagtttttc aaagtcaatt tcctaatcta aacattgatt acttgctcct
    10381 ggacactgag cagattgatc ttgatagcta tctagatgct gacataatta tcatcggtgg
    10441 tggaaatacg gaaaaatata ttgctaactt atgttaatca ggagttcaaa agttatatcg
    10501 atcatatgct taataaagag gcaaaaatta taggattttc tgcaggagcc ctactattag
    10561 gagaaaaagt ctatgtctca cctaatgata attcagatca tcagataaag ataaaaaatg
    10621 gattaggact ctttagtcag tttttaatta gtgtccatta tgattcctgg aatgataaag
    10681 caaataagga tagagctgaa gaactcgtta atgttcccat aattccacta aatgatcatt
    10741 cttgtcttgt attggataaa cttggaaaca tcatagagaa aattgactaa ctttcataat
    10801 gtaaaaatgg atctaggaaa taaaagtgta gacgaactgg ataggttact agtgaaaact
    10861 gcaaaaagtg ttgtaaagtg aatcggagtg tgcttgatgg attttagtag taagatagcc
    10921 ataaataagg gctggtcaga tgataaaaaa tattgtgtga cagatcaaaa tcagtaaaaa
    10981 tatttcttgc gtgtttctga taagtcgaag ttagattata aaaaaatttg aatttgatat
    11041 gatggagaaa gtagcttctc ttggagttcc gatgtgtaaa ccaattagca ttgaactctg
    11101 cgatgacgaa gtacattctt tacacgaatg gatagacgga agagatgcaa tagatagcat
    11161 tttagcttat tcagaaaacc aacaatacac atatggtgta gaagcaggaa agatacttag
    11221 aaagattcat acaattcctg ctacagaagt ttgtgaagat tgggaaattt ttttaatcta
    11281 aaaattgatg ataaaatctc caacgaaatg atatggtaag tccgaaacgc tcagtgtgta
    11341 agcttgttgc taaaagcgta aaaaccttgg aacgaaagga ataatagact tcctgcgaaa
    11401 caaaaataca atacaataaa actatggatg atgaagcaag taaacaatta agcgatagcc
    11461 gtttcaagat ccttgtaggt gttcagcgca cgacttttga agagatgtta gctgtgttaa
    11521 aaacagctta tcaacgtaaa cgcgcaaaag gtggacgaaa aagcaaatta agcctagacg
    11581 atctccttat ggtaactatt caatacatgc gagaatagag cacttatgaa caaattgcgg
    11641 ctgattttgg cattcacgaa agcaacttaa tccgtcggag tcaatgggtt gaagcaactc
    11701 ttattcaaaa tggttttacg atttcaaatt ctgccttaat tctgtaaaaa cagtaaaatt
    11761 cgaaggattg taaggtaaga gtttttttct ttctgaaaaa atggtataat agcaatcaaa
    11821 actagaaaat aaaacggaat ttggaacaga tttgtctgta tcctagtaga gtggtgatac
    11881 tatgaagatt agtaagaggc acttattaaa ttattccatc ttgattccct acttgctttt
    11941 atctattttg ggcttgattg tggtctattc gaccaccagt gctattttaa ttgaagaagg
    12001 caagagcgcc ttgcagttgg ttcgaaacca aggaatcttt tggattgtta gtttgatact
    12061 gattgcctta atttataaat tgagactaga ttttttgaga aatgagcgac taatcatttt
    12121 agttatatta atagaaatgc ttttattgtt cttggctcgt tttattggta tttcagtaaa
    12181 cggggcatac ggttggattt cggttgcagg agtaactatt cagccagctg agtacttaaa
    12241 aatcattatt atttggtatt tagctcaccg attctccaaa cagcaagaag aaatagctac
    12301 ttatgatttt caagttttga ctcaaaatca atggcttccc cgtgctttta atgattggcg
    12361 attcgttctc ctagttctga ttggaagttt gggaattttc cctgatttag gaaatgcgac
    12421 tattttagtc ttggtttcct tgattatgta tacagttagt ggaatcgctt atcgctggtt
    12481 ttcaaccatt ctggcgctcg tatctgccac ttctgtcttt gtcttgacca ctatcagcct
    12541 aatcggtgtt gagacctttt caaaaattcc agtatttggc tatgtagcca agcgctttag
    12601 tgcctttttt aatccttttg ccgatcgtgc tgatgcaggt caccagttag ctaattctta
    12661 ttttgccatg gtcaatggtg gttggtttgg tctaggtctt ggaaactcga ttgaaaaacg
    12721 aggttatttg ccagaagctc atacagactt tgtcttttct atcgtgattg aagaatttgg
    12781 ctttgttggt gccagtctta ttttagctct cttgtttttc atgattttgc ggattatctt
    12841 ggtcggtatc cgagcggaga atcctttcaa tgccatggtt gcactcggtg tcggagggat
    12901 gatgttggtt caggtatttg tcaatatcgg agggatttcg ggcttgattc catctacagg
    12961 agtgactttc cctttcttat cccagggtgg aaatagtctt ctagtcttat cagtggcagt
    13021 agcctttgtc ttaaatattg atgccagtga aaaacgcgct aagttgtacc gagaattgga
    13081 aaatcaacca atgaaccttc tgttgaagta ggataaagaa aggatagttt atgtctcttc
    13141 aaaaattaga aaattatagt aataaaagtg ttgtgcaaga agaagtcttg attctaacag
    13201 aattactgga agatattact aaaaatatgc ttgccccaga gacctttgaa aaaataatac
    13261 agttgaaaga attatcaacg caggaagatt atcaaggtct aaaccgtcta gtgactagct
    13321 tatcaaatga tgaaatggtc tatatttcac gctatttctc tatcttacct cttttgatta
    13381 atatttcaga ggatgtggat ttagcttatg aaatcaatca tcaaaataat attgatcagg
    13441 actatttagg taaattatct acaacgatta aattggtagc agaaaaggaa aatgccgttg
    13501 agatcctaga acacttgaat gttgtccctg ttttgacagc ccatccaaca caagtgcaac
    13561 gcaaaagtat gttggattta acaaatcata ttcatagtct tttgcgtaaa taccgtgatg
    13621 ttaagttggg gttgatcaat aaagataaat ggtacaatga tttgcgtcgt tacatcgaaa
    13681 ttatcatgca gacagacatg attcgtgaga aaaaattaaa agtgactaac gaaatcacga
    13741 atgctatgga atattataac agctcctttt tgaaagctgt acctcatttg acgacggagt
    13801 ataagcgctt agcgcaagcg catggtctga atttaaaaca ggctaaacca atcaccatgg
    13861 gtatgtggat aggtggtgac cgtgatggaa atccatttgt tacagcaaag accttgaagc
    13921 agtctgcact cactcagtgt gaagtcatca tgaactacta tgataaaaag atttaccaac
    13981 tttatcgtga attttctctt tcaactagca ttgtcaacgt cagcaagcaa gtcagagaaa
    14041 tggctcgtca atccaaggat aactcgattt accgcgaaaa agagctttac cgtcgtgcct
    14101 tgtttgatat tcaatcaaaa attcaggcaa ctaaaaccta tctgattgag gatgaagaag
    14161 ttgggactcg ttatgaaacc gccaatgatt tctacaagga tttgattgcc attcgagatt
    14221 ctctactaga aaataagggc gagtccttga tttcaggtga ttttgtggaa ttattgcagg
    14281 cagtagagat atttggtttt tacttagcat caattgatat gcgacaagac tctagcgtct
    14341 atgaagcctg tgtggcagaa ctcttgaaat cagcaggaat tcattctcgt tatagcgagt
    14401 tgagcgaaga agaaaagtgt gaccttctct tgaaagaatt agaagaagat ccccgaattc
    14461 tttctgcgac tcacgcagaa aaatcagaat tattagcaaa agaattagct atttttaaga
    14521 cggctcgtgt tttgaaagat aagttgggag atgatgtcat ccgtcagacc atcatttcac
    14581 atgcaaccag cctttctgat atgctagaat tagctattct gttaaaagaa gtaggactgg
    14641 tggatacgga aagggcgcgt gttcagattg ttcccctttt tgaaacaatt gaagacttgg
    14701 atcattcaga ggaaacaatg agaaaatatc tttctcttag ccttgccaaa aaatggattg
    14761 actcacgaaa taactaccaa gaaatcatgc ttggctactc tgacagtaat aaagatggcg
    14821 gttacttgtc atcatgttgg accctctaca aggctcaaca acaattgact gctattggag
    14881 atgaatttgg cgttaaggtt accttcttcc atggtcgtgg tggtactgtc ggtcgtggtg
    14941 gtgggccaac ctatgaagcc attacatctc aaccgctcaa gtctatcaag gatcgtatcc
    15001 gcttgacgga gcagggtgaa gtaattggga ataaatacgg taacaaagac gccgcttact
    15061 ataaccttga aatgctagta tcggcagcta ttaaccgtat gattactcag aagaagagcg
    15121 ataccaatac cccaaatcgt tatgaagcca ttatggatca agtagtggac cgtagttacg
    15181 atatctaccg tgatttggtc tttggtaatg agcatttcta tgattatttc ttcgagtcaa
    15241 gtccaatcaa ggctatttca agttttaata ttggttctcg tccagccgct cgtaagacta
    15301 ttactgaaat cggtggtttg cgtgccatcc cttgggtatt ctcatggtca cagagtcgtg
    15361 ttatgttccc tggatggtac ggggttggtt caagcttcaa ggaatttatc aataaaaatc
    15421 cagagaatat tgctatctta cgagatatgt accaaaattg gcctttcttc caatcgcttc
    15481 tttcaaatgt tgatatggtt ttgtcaaaat caaatatgaa tattgctttt gaatatgcta
    15541 aactttgtga agacgagcaa gttaaggcca tctatgagac tattttaaat gaatggcaag
    15601 ttactaagaa cgttatcttg gctattgaag gacatgacga actcttagct gacaatccat
    15661 atctaaaagc tagtctggat taccgtatgc cttactttaa tattctcaac tatattcagt
    15721 tagagttgat taaacgccaa cgtcgtggag aattgtccag tgatcaagaa cgattgattc
    15781 atatcaccat caacggaatt gcgacaggat tgcgtaattc aggttgataa ttttcaagag
    15841 tgaatactaa aagtgaatat caaaaaaatt ctaatagact attgacaagt aatttaaaaa
    15901 tgatataatt taaccattca gaaaagtaat catacaaact ttttagagag tctgtggtag
    15961 ctgaaaacag ataagtggcg atgatgaaaa ttgggctgaa tgctatttag aatttgaaat
    16021 tataaaaatt cggtaagcac accttacagt gcatctcgtt attgcgagac tgagcgatag
    16081 ggaaattccc tataattgag gtggtaccgc gcatcgacgt cctcacacaa gttttttgtg
    16141 tgaggatttt tttgatggag gttagtatgg aaagaaaacg atggcgtcgc ttgtttagat
    16201 aagtgaaata tgttaaagga aataaaaagg agaaacagaa tgaaaaataa acgtttaatt
    16261 ggaattattg ctgcattagc agtcttagta gcaggaagct tgatttattc ttcaatgaat
    16321 aaatcagaag ctcagaataa taaggatgag aagaaaataa ccaagattgg tgtgcttcaa
    16381 tttgtgagcc atccatccct tgatttgatt tataaaggga tccaagatgg acttgcagaa
    16441 gaaggatata aagatgatca agttaaaatt gattttatga actcagaagg tgaccaaagt
    16501 aaggttgcga caatgagtaa acaattggtt gcaaatggga atgaccttgt ggttggtatc
    16561 gcaacaccag cagcccaagg gttggctagt gcaacaaaag acttaccggt tatcatggcc
    16621 gctattacag acccaattgg tgctaacttg gttaaagatt tgaaaaaacc aggtggcaac
    16681 gttacagggg tatctgacca caatccagct caacaacaag ttgaactcat caaggctctg
    16741 acaccgaatg tgaaaacaat cggagctctt tactcaagta gcgaagacaa ttcaaaaaca
    16801 caggtcgaag aatttaaggc ttatgctgaa aaagcaggtc tgacagtgga aacatttgca
    16861 gttccttcaa caaatgaaat tgcctcaact gtcactgtta tgactagcaa ggtagatgct
    16921 atttgggttc caattgataa caccattgca tcaggatttc caacggttgt ctctagcaat
    16981 caaagttcta agaaaccaat ttatcccagt gcgacagcta tggtagaagt aggtggtttg
    17041 gcatcagttg taattgacca acatgacctt ggtgtggcaa caggtaaaat gattgtgcaa
    17101 gtcttgaaag gtgcaaaacc agccgatacc ccagtcaatg tcttttcaac tggtaagtca
    17161 gtcatcaata aaaaaatagc acaagaacta ggtattacta ttcctgagtc tgttctcaaa
    17221 gaagcaggac aagtcatcga ataaataagg tagggaggag gagactcttc ccatttttta
    17281 aaaagatgaa tatagaaagg attaaataaa atatgattgt ttccattatt tctcaaggat
    17341 ttgtctgggc tattctaggt ctgggaatct ttatgacatt taggatttta aactttccag
    17401 atatgacgac agaaggttcc ttccctcttg ggggagctgt tgctgtcact ttgataacca
    17461 aaggcgtgaa cccattttta gcgacacttg ttgctgtagg agcaggttgt ttggctggaa
    17521 tggcagcagg ccttctttat acaaaaggga agatcccaac cttgctctca gggattttgg
    17581 tgatgacttc ttgtcactca atcatgctct tgattatggg acgtgcgaat ttaggcctgc
    17641 ttggaaccaa gcaaattcag gatgttttgc cttttgattc ggatttgaat caactcttga
    17701 caggtctcat ctttgtgagt attgttattg ctctcatgct ctttttcttg gacactaaac
    17761 tcggacaagc ctatattgct acaggggata atcctgatat ggctagaagt ttcgggattc
    17821 atactggacg catggagctc atgggcttgg tcttatcaaa tggtgtgatt gcccttgcag
    17881 gtgccctcat tgctcagcaa gaaggctatg ccgatgtgtc tcgagggatc ggggttatcg
    17941 ttgtggggct tgcaagtttg attattggag aagttatttt caagagtttg agcttggcag
    18001 agcgtttggt tactatcgtt gtaggttcta tcgcttatca atttttagtg tgggcagtta
    18061 tcgcacttgg ctttaataca agttaccttc gtttatacag tgccttgatt ttagcagtct
    18121 gcctcatgat tccaacattt aagcaaacaa tcttgaaagg agccaagtta agcaaatgac
    18181 agcaattgta gaattaaaaa atgcaaccaa aatcgttaaa aatggctttg atgaagaaaa
    18241 gattatttta aatgatgttt ccttagaaat ttttgaacgg gactttatca cgattttggg
    18301 cggaaatggt gctggaaaat caactctctt taacactata gcagggacct tatcactaac
    18361 tagtggaact atccgtattt taggtgaaga tctcactaag ttttcacccg agaagcgtgc
    18421 caagtacctg tctcgtgtct tccaagatcc aaagatgggg acagctcccc gtatgacggt
    18481 cgctgaaaat cttttaatcg ccaagtttcg tggtgaaaag cgtggattgt taccaagacg
    18541 cttgactagc tataaggatg aatttcaggc aaccattgaa aaagtaggaa atggtcttga
    18601 gaaacacttg aatacaccga ttgagttctt atcaggtgga caaagacagg ctttgagtct
    18661 cttgatggca accttgaagc gacctgaatt actcctgtta gatgagcata ctgctgccct
    18721 ggatccaaag actagtgttg ctttgatgga attgacagat gaatttgtta agaaagatca
    18781 gctaacagcc cttatgatta ctcatcatat ggaagatgct ctcaaatacg gcaatcgctt
    18841 gattgtcatg aaagaaggac ggattatcca agatttaaac caagaagaaa aagcaaaaat
    18901 gaaaatctct gattattatc aactctttga ataaagtagg gaaaatgagt gaaatggttt
    18961 actttttttc tgaaataaag tatactatat aaagtaaact atgataacat ggaggtattg
    19021 tgtatggttg acaaacaagt cattgaagaa atcaaaaaca atgccaacat tgtggaagtc
    19081 ataggagatg tgatttcttt acaaaaggca ggacggaact atctagggct ctgtcctttt
    19141 catggtgaaa aaacaccttc tttcaacgtt gtagaggaca agcagtttta ccactgtttt
    19201 ggttgtggtc gctcaggtga tgtctttaaa ttcatcgagg agtaccaagg ggttaccttt
    19261 atggaggctg tccaaatctt aggtcagcgt gtcgggattg aggttgaaaa accgctttat
    19321 agtgaacaga agccagcctc gcctcaccaa gctctttatg atatgcacga agatgcggct
    19381 aaattttacc atgctattct catgacaacg actatgggcg aagaggccag aaattacctt
    19441 tatcagcggg gtttgacaga tgaagtgctt aaacattttt ggattggttt agcacctcca
    19501 gaacgaaact atctctatca acgtttgtct gatcagtatc gtgaagaaga tttactggat
    19561 tcaggcctgt tttatctctc ggatgccaat caatttgtag acacctttca caatcgcatt
    19621 atgtttcccc tgacaaatga ccaaggaaag gtcattgcct tctcaggtcg tatctggcaa
    19681 aaaacagatt cacaaacttc taagtataaa aacagccgat cgactgcaat ttttaacaaa
    19741 agttacgaat tatatcatat ggatagggca aaaaaatctt ctggaaaaac tagtgagatt
    19801 tacctgatgg aaggattcat ggatgttatt gcagcctatc aggctggaat cgaaaatgct
    19861 gtggcgtcga tgggaacggc cttgagtcga gagcatgttg agcatctgaa aaggttaacc
    19921 aagaaattgg ttcttgttta cgatggagat aaggctgggc aagccgcgat attgaaagca
    19981 ttggatgaaa ttggtgatat gcctgtgcaa atcgttagca tgcctgataa cttggatcct
    20041 gatgagtatc tacaaaaaaa tggtccagaa gacttggcct atctattaac gaaaactcgt
    20101 attagtccga ttgagttcta cattcatcag tacaaacctg aaaacagtga aaatctgcag
    20161 gctcagattg agtttattga aaaaatagct cccttgattg ttcaagaaaa gtccatcgct
    20221 gctcaaaaca gctatattca tattttagct gacagtctgg cgtcctttga ttatgcccag
    20281 attgagcaga ttgttaatga gagtcgtcag gtgcaaaggc agaatcgcat ggaaggaatt
    20341 tccagaccga cgccaatcac catgcctatc accaagcagt tatcggctat tatgagggca
    20401 gaagcccatc tactctatcg gatgatggaa tcccctcttg ttttgaacga ttaccgtttg
    20461 cgagaagact ttgcatttgc tacacctgaa tttcaggtct tatatgactt gcttggccag
    20521 tatggaaatc ttcctccaga agttttagca gagcagacag aggaagttga aagagcttgg
    20581 taccaagttt tagctcagga tttgcctgct gagatatcgc cgcaggaact tagtgaagta
    20641 gagatgactc gaaacaaggc tctcttgaat caggacaata tgagaatcaa aaagaaggtg
    20701 caggaagcta gccatgtagg agatacagat acagccctag aagaatttga acgtttaatt
    20761 tcccaaaaga gaagaatgga gtaataatgg caacaaaaca aaaagaagta acaacatttg
    20821 acgtacaggt agcagaattt atccgtaatc ataagcaaaa agggacagca acagatgatg
    20881 aaatcaatgc aagtctggtt attcctttta ccttggacgc tgatgggatt gaagatctct
    20941 tgcaacggat tcaggatgca ggcatttcta tcacagataa cgaaggaaat ccaagtgcgc
    21001 gtgttcttag caatgaagaa gaaccagaac tcagcgatga ggacttgatt gggtcaactt
    21061 ctgctaaggt caatgaccct gtccgtatgt acttgaaaga aataggggtc gttcctctct
    21121 tgaccaatga agaggagaaa gagttggcac tggctgttga agctggcgat atcgaagcca
    21181 aacaacgtct tgcggaagcc aatcttcgtt tggttgtttc tattgccaaa cgctatgtcg
    21241 gtcgtggcat gcagttcctt gacttgattc aagaaggaaa tatgggcttg atgaaggcgg
    21301 ttgacaagtt tgactattct aaagggttca agttttcaac ttatgcaact tggtggattc
    21361 gtcaggctat cactcgtgct attgcggatc aagctcgtac catccgtatc ccagttcaca
    21421 tggttgaaac tatcaataaa ttggttcgtg aacagcggaa tctccttcaa gaattggggc
    21481 aagatccgac accagaacag attgctgaac gaatggatat gacacctgat aaggttcgtg
    21541 aaatcttgaa gattgcccaa gaaccagtat ctcttgaaac tcctatcggt gaagaggacg
    21601 atagccacct tggagacttt atcgaagatg aagtgattga aaatccagtg gattatacga
    21661 ctcgtatcgt cttgcgtgag caattggatg aaatcttaga tactcttaca gaccgtgaag
    21721 aaaatgttct gcgtctacgt tttggactag atgatggaaa aatgcgcaca cttgaagatg
    21781 tggggaaagt ctttaacgta actcgtgagc gtatccgtca gattgaagca aaggctttga
    21841 gaaaactacg ccaaccaagc cgcagcaaac cgcttcgtga ttttattgaa gactaagagt
    21901 gaggaaaata tggcttatac agaagagcaa attgaaaaca tcaaaacacg gattttaaca
    21961 gccttggaag aagtcatcga ccctgagttg ggaatcgata ttgtcaatct tggtttgatc
    22021 tatgagattc gttttgacgg tgacacaggg caaacagaga ttgacatgac tttgacaact
    22081 atgggttgtc ccttagcaga ccttttgaca gaccagattt atgatgctat gatagaggtt
    22141 ccagaagtaa cggatactga ggttaaatta gtctggtatc cagcctggac agttgaaaaa
    22201 atgagtcgct atgcccgcat tgccctaggc attaagtaaa catataaaag catgtgagag
    22261 actgttggaa aagcgaggaa atttcccctc ttttcctcta gtctctcctt tcttttgctg
    22321 attttattca aagaaaatga tataatagta gttatggaga aaaagaaatt acgcatcaat
    22381 atgttgagtt caagtgagaa agtagcagga cagggagttt caggtgctta ccgtgaatta
    22441 gttcgtcttc ttcaccgtgc tgccaaggac caattgattg ttacagaaaa tcttccaatc
    22501 gaggcagatg tgactcactt tcatacgatt gattttccct attatttatc aaccttccaa
    22561 aagaaacgct cagggagaaa gattggctat gtgcatttct tgccagctac acttgaagga
    22621 agtttgaaaa ttccattttt cttaaaggga attgtgaaac gctatgtatt ttctttttac
    22681 aaccggatgg agcacttggt tgtggtcaat cctatgttta ttgaggattt ggtagcagct
    22741 ggtattccac gtgaaaaagt gacctatatt cctaactttg tcaacaagga aaaatggcat
    22801 cctctaccac aagaagaggt agtcagactg cgcacagatc ttggtcttag tgacaatcag
    22861 tttatcgtag taggtgctgg gcaagttcag aaacgtaaag ggattgatga ctttatccgt
    22921 ctggctgagg aattgcctca gattaccttt atctgggctg gtggcttctc ttttggtggt
    22981 atgacagatg gttatgaaca ctataagaaa attatggaaa atccccctaa aaatttgatt
    23041 tttccaggca ttgtatcgcc agagcggatg cgcgaattgt atgctctagc ggatcttttc
    23101 ttgttgccta gttacaatga gctctttcct atgactattt tagaagctgc gagttgtgag
    23161 gctcctatta tgttgcgtga tttagatctc tataaggtga ttttggaggg aaattatcgg
    23221 gcgacagcgg gtagagaaga gatgaaagag gctattttgg aatatcaagc aaatcctgct
    23281 gtcttaaaag atctcaaaga aaaggctaag aatatttcca gagagtattc tgaagagcat
    23341 ctgttacaaa tctggttgga cttttatgag aaacaagccg ctttagggag aaagtaaaaa
    23401 gtgaggtaat ctatgcgaat tggtttattt acagatacct attttcctca ggtttctggt
    23461 gttgcgacca gtattcgaac cttgaaaaca gaacttgaaa agcagggaca tgctgttttt
    23521 atctttacga cgacagataa ggatgtcaat cgctacgaag attggcaaat tatccgcatt
    23581 ccaagtgttc ctttctttgc ttttaaggat cgtcgctttg cctaccgagg ttttagcaag
    23641 gcacttgaaa ttgctaaaca gtatcagcta gatattatcc atactcagac agaattttct
    23701 cttggcctgt tggggatttg gattgcgcgt gaattgaaaa ttccagtcat ccatacctat
    23761 cacacccagt atgaagacta tgtccattat attgctaagg ggatgttgat ccggccgagt
    23821 atggtcaagt atctggttag aggtttcctg catgatgtgg atggggttat ttgccctagt
    23881 gagattgtcc gtgacttgct atctgattat aaggtcaagg ttgaaaaacg gatcattcct
    23941 actgggattg aattagccaa gtttgagcgt ccggaaatca agcaggaaaa tttgaaagaa
    24001 ctgcgtagta aactagggat tcaagatggt gaaaagacgt tgcttagtct ttcgagaatc
    24061 tcctatgaaa aaaatattca agcagtttta gcagcctttg ctgatgttct gaaagaggaa
    24121 gacaaggtta aactggtagt agctggggat ggcccttatc tgaatgacct caaagagcaa
    24181 gcccagaacc tagagattca agactcagtc atctttacag ggatgattgc tcctagtgag
    24241 acggctcttt actataaagc ggcggatttc ttcatttcgg catcgacaag cgaaacgcaa
    24301 ggtttgacct acttggaaag cttagccagt ggaacacctg tcattgctca cggaaatcct
    24361 tatttgaaca acctcatcag tgataaaatg tttggaacct tgtactatgg agaacatgat
    24421 ttggctggtg ctattttgga agccctgatt gcaacaccag acatgaacga gcatacctta
    24481 tcagagaaat tgtatgagat ttcagctgag aactttggga aacgagtgca tgagttttat
    24541 ctggatgcca ttatttcaaa taacttccag aaagatttgg ctaaagatga tacggtcagt
    24601 cagcgtatct ttaagacagt tttgtatctt cagcaacagg tggttgctgt acctgtaaaa
    24661 ggatctagac gcatgttgaa ggcttcaaaa acacagttga tcagtatgag agactattgg
    24721 aaagaccatg aagaatagaa agaggaacag ctatgaaaaa aacaattaat gagaagcggt
    24781 cgtgataaaa agattgcggg tgtttgtgct ggggtggccc attatctgga tatggatccg
    24841 actatcgttc aagtcatttg gggtgttctt acttgctgtt acggagctgg aattgtagct
    24901 tacattattt tatggattat cgcaccagta gcaactgact attgaaaact agctcaattc
    24961 atgctaagat aatagaaaat agaatgtaac gaaggagaga aaaatggcat ttggagataa
    25021 tggaaatcgt aaaaaaacta tgtttgagaa aataaccttg tttatcgtga ttatcatgct
    25081 agtagcaagt ttattgggaa tttttgcaac tgcaattggt gccctcagta atctataaaa
    25141 tagattcaag aaaatttagt gactgggatt tcccagccct tttttaaagt gagaagaaat
    25201 aatgagtatg tttttagata cagctaagat taaggtcaag gctggtaatg gtggcgatgg
    25261 tatggttgcc tttcgtcgtg aaaaatatgt ccctaatgga ggcccttggg gtggtgatgg
    25321 tggtcgtgga ggcaatgtgg tcttcgttgt agacgaagga ctacgtacct tgatggattt
    25381 ccgctacagt cgtcatttca aggctgattc tggtgaaaaa gggatgacca aagggatgca
    25441 tggtcgtggt gctgaggacc ttagagttcg agtaccacaa ggtacgactg ttcgtgatgc
    25501 ggagactggc aaggttttaa cagatttgat tgaacatggg caagaattta tcgttgccca
    25561 cggtggtcgt ggtggacgtg gaaatattcg tttcgcgaca ccaaaaaatc ctgcaccgga
    25621 aatctctgaa aatggagaac caggtcagga acgtgagtta caattggaac taaaaatctt
    25681 ggcagatgtc ggtttagtag gattcccatc tgtagggaag tcaacacttt taagtgttat
    25741 tacctcagct aagcctaaaa ttggtgccta ccactttacc actattgtac caaatttagg
    25801 tatggttcgc acccaatcag gtgaatcctt tgcagtagcc gacttgccag gtttgattga
    25861 aggggctagt caaggtgttg gtttgggaac tcagttcctc cgtcacatcg agcgtacacg
    25921 tgttatcctt cacatcattg atatgtcagc tagcgagggc cgtgatccat atgaggacta
    25981 cctagctatc aataaagagc tggagtctta caatcttcgc ctcatggagc gtccacagat
    26041 tattgtagct aataagatgg acatgcctga gagtcaggaa aatcttgaag actttaagaa
    26101 aaaattgtct gaaaattatg atgaatttga agagttaccg gctatcttcc caatttctgg
    26161 attgaccaag caaggtctgg caacactttt agatgctaca gctgaattgt tagacaagac
    26221 accagaattt ttgctctacg acgagtccga tatggaagaa gaagcttact atggatttga
    26281 cgaagaagaa aaagcctttg aaattagtcg tgatgacgat gcgacatggg tactttctgg
    26341 tgaaaaactc atgaaactct ttaatatgac caactttgat cgtgatgaat ctgtcatgaa
    26401 atttgcccgt cagcttcgtg gtatgggggt tgatgaagcc cttcgtgcgc gtggagctaa
    26461 agatggggat ttggtccgca ttggtaaatt tgagtttgaa tttgtagact aggagactgg
    26521 tatgggagat aaaccgatat ctttccgaga tgcggatggt aattttgttt ccgccgcaga
    26581 cgtttggaat gaaaagaaat tggaagaact atttaatcgt ctcaatccaa atcgtgcctt
    26641 gagattggca cgaactaaaa aggaaaatcc atctcagtaa agaagctaaa aaatcccgtg
    26701 cctcatcaga cacgggattt tgtggtacga cgggcatgta tagcgaactg aatctggaat
    26761 agcacagcat atcttctaaa atatagtaaa atg
//
LOCUS       DAVLDI010000028        26575 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLDI010000028 DAVLDI010000000
VERSION     DAVLDI010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26575
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.028"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(135..902)
                     /locus_tag="VXD01_001210"
     CDS             complement(135..902)
                     /locus_tag="VXD01_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV0601617.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(899..1765)
                     /locus_tag="VXD01_001211"
     CDS             complement(899..1765)
                     /locus_tag="VXD01_001211"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV0601618.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(1802..3169)
                     /gene="accC"
                     /locus_tag="VXD01_001212"
     CDS             complement(1802..3169)
                     /gene="accC"
                     /locus_tag="VXD01_001212"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV0601619.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(3181..3603)
                     /gene="fabZ"
                     /locus_tag="VXD01_001213"
     CDS             complement(3181..3603)
                     /gene="fabZ"
                     /locus_tag="VXD01_001213"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV0601620.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(3600..4085)
                     /locus_tag="VXD01_001214"
     CDS             complement(3600..4085)
                     /locus_tag="VXD01_001214"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV0601621.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(4088..5323)
                     /gene="fabF"
                     /locus_tag="VXD01_001215"
     CDS             complement(4088..5323)
                     /gene="fabF"
                     /locus_tag="VXD01_001215"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV0601622.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFIKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEYAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAVKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(5345..6076)
                     /gene="fabG"
                     /locus_tag="VXD01_001216"
     CDS             complement(5345..6076)
                     /gene="fabG"
                     /locus_tag="VXD01_001216"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV0601623.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(6110..7030)
                     /gene="fabD"
                     /locus_tag="VXD01_001217"
     CDS             complement(6110..7030)
                     /gene="fabD"
                     /locus_tag="VXD01_001217"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV0601624.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPVVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEATVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(7023..7997)
                     /gene="fabK"
                     /locus_tag="VXD01_001218"
     CDS             complement(7023..7997)
                     /gene="fabK"
                     /locus_tag="VXD01_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV0601625.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(8116..8340)
                     /locus_tag="VXD01_001219"
     CDS             complement(8116..8340)
                     /locus_tag="VXD01_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV0601626.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(8400..9374)
                     /locus_tag="VXD01_001220"
     CDS             complement(8400..9374)
                     /locus_tag="VXD01_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV0601627.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLISLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(9374..9808)
                     /locus_tag="VXD01_001221"
     CDS             complement(9374..9808)
                     /locus_tag="VXD01_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0601628.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(9902..10687)
                     /locus_tag="VXD01_001222"
     CDS             complement(9902..10687)
                     /locus_tag="VXD01_001222"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV0601629.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            11012..12376
                     /locus_tag="VXD01_001223"
     CDS             11012..12376
                     /locus_tag="VXD01_001223"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV0601630.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            12379..12750
                     /locus_tag="VXD01_001224"
     CDS             12379..12750
                     /locus_tag="VXD01_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV0601631.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIARKKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            12964..14238
                     /gene="serS"
                     /locus_tag="VXD01_001225"
     CDS             12964..14238
                     /gene="serS"
                     /locus_tag="VXD01_001225"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV0601632.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(14263..15162)
                     /locus_tag="VXD01_001226"
     CDS             complement(14263..15162)
                     /locus_tag="VXD01_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV0601633.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDMLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPERRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(15272..15820)
                     /locus_tag="VXD01_001227"
     CDS             complement(15272..15820)
                     /locus_tag="VXD01_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV0601634.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(16038..17360)
                     /locus_tag="VXD01_001228"
     CDS             complement(16038..17360)
                     /locus_tag="VXD01_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV0601635.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPVITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLIVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(17451..17539)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(17703..20039)
                     /locus_tag="VXD01_001229"
     CDS             complement(17703..20039)
                     /locus_tag="VXD01_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV0601636.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(20143..20691)
                     /locus_tag="VXD01_001230"
     CDS             complement(20143..20691)
                     /locus_tag="VXD01_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV0601637.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(20688..20990)
                     /gene="zapA"
                     /locus_tag="VXD01_001231"
     CDS             complement(20688..20990)
                     /gene="zapA"
                     /locus_tag="VXD01_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV0601638.1"
                     /translation="MANLNRFKFTFGKKTLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            21077..21958
                     /locus_tag="VXD01_001232"
     CDS             21077..21958
                     /locus_tag="VXD01_001232"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV0601639.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            21962..22576
                     /gene="lepB"
                     /locus_tag="VXD01_001233"
     CDS             21962..22576
                     /gene="lepB"
                     /locus_tag="VXD01_001233"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV0601640.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            22656..22778
                     /locus_tag="VXD01_001234"
     CDS             22656..22778
                     /locus_tag="VXD01_001234"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HEV0601641.1"
                     /translation="MKIKEQTRKLAVGCLKQCFEVVDRTDEVSSKYCFEVADGS"
     gene            22855..25221
                     /locus_tag="VXD01_001235"
     CDS             22855..25221
                     /locus_tag="VXD01_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV0601642.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYIFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKNNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILDAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(25269..26552)
                     /locus_tag="VXD01_001236"
     CDS             complement(25269..26552)
                     /locus_tag="VXD01_001236"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV0601643.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAQFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT         7642 a         6149 c         5209 g         7575 t
ORIGIN      
        1 tttttgtaag cttacatcta cagtatacat cttttttgtc tattttatag cccatctcct
       61 caactgtcaa tttttcaacc tgaattgcat ttttccataa aaaatgagac ctttctagtc
      121 tcatttagtc attcttagta ttttctaaat cgttgatagc gttcttccag caactcttct
      181 agcggttttt gtgaaagtct agccagctcc gtttggagtt cttttttgac actcttaatc
      241 agttctttac tagaaagtcc tacttcagaa atcaccttat ccaccacgtc catttctaac
      301 agttcatgcg aagtgatttt catcagttct gctgcttcca tggcgcgagt accgtccttc
      361 cataaaatgg aagcaaagcc ttctggactg agaatggcat agatagaatt ttccagcatc
      421 cagacacggt ccgcgacagc tagagccaga gccccgcctg aaccaccttc accgataata
      481 atggcgataa taggaacttt caggtcactc atttccatga gattgcgagc gatagcttcc
      541 ccttgaccac gttcttccgc tccgacacca ggataagcac ctgctgtgtt gataaaggtc
      601 acaactggac ggccaaattt ctcagcctgt ttcatcaacc gcagtgcctt tcggtagcct
      661 tctggatgtg gttggccaaa attccgtttg aggttgtctt gcaaactctt gcctttttgg
      721 ataccaacca ctgttacagc ttggtctcca agccaaccaa taccaccaac aactgcacca
      781 tcatcacgaa aagaacggtc accatgtaat tggataaatt catcaaaaat gcctgtcgca
      841 aagtccaagg ttgtcaagcg actctgctca cgcgcttctc tgactatttt tgcaatattc
      901 atctaggact ccctccatgc aatctgacta ggctagcaat cgtatctggt aagtctcttc
      961 ttttgacaat agcatccaca aagccatgtt ctaataggaa ttctgccttt tggaaatcct
     1021 caggcaagct ttcacgaacc gtattttcaa tcacacgacg cccagcaaaa ccaaccaagc
     1081 tctgtggttc agccagaatg atatcgcctt ccatagcgaa agatgctgtc acaccaccag
     1141 tcgttggatc tgtcaaaatg gtcaggtaaa agagaccagc atttgaatgg cgtttaaccg
     1201 ccgcagagat cttagccatc tgcatgagac tcatgattcc ttcctgcata cgggctccac
     1261 cagaggctgt gaataggaca actggcaatt tttcgacagt cgcatactca aacaaacgag
     1321 tgattttttc acctacaacc gtacccatag aagccatgat aaagttagaa tccataatcc
     1381 caagagccac agtctgacct ttaataagag cagttcctgt cacaacggct tcatgcagac
     1441 ctgttttttc acgcatagat gccagtttct tttggtaacc agggaaatgc aagggatcct
     1501 tgctttcaat ccctgtaaac aattctttga aggttcccat atcaatcgtc aaagccaagc
     1561 gttcttgggc agaaatacga aaggtatagc tacagtgcgg acagatacgt tcacttccca
     1621 gatccttctg atagatggta tgcttacagc ctggacactg ggaaaataat tcatctggaa
     1681 cctctggctt agcttgaggt ttttccctaa ccgaacgatt gggattgatt cgaatatact
     1741 tatctttttt actaaataga gccattgatt ccccttttcg gtttaaactc ttaaagtcat
     1801 tttattcttt ttcttgatat ttaggtaaga aggtttccat caagaaggaa gtatcataat
     1861 ccccagcaat gacattgcga tctgaaatga ggtcaagctg gaaatctgca ttagtctgca
     1921 ctccttcaat ctctaattca tagagggcac gttgcatttt catcaaggcg tcaaaacgat
     1981 tttcgccgtg tactatgatt ttggcaatca tactatcata ataaggcgga atggtataac
     2041 ctggataaac tgctgaatcc acgcgcaagc caactccacc acttggcaga tagagattag
     2101 taatcttacc tggacttgga gcaaagttaa aggctgggtt ttctgcattg atacgacact
     2161 cgatggcatg accacgtagg acaatatctt cttgcttaac agacaaaggc tgacctgccg
     2221 caatgcaaat ctgttcctta acgatatcaa cacctgaaac aaactctgtt actggatgtt
     2281 ctacctgaac acgagtattc atctccatga aatagaaatt gctacttgct tcatcaagaa
     2341 gaaattcaat ggttcctgca ttctcatagc caacaaactc tgccgctcga acagcagcag
     2401 cacctatttc atgacgcagc gtttttccga ttgcaatcga gggactttct tccaaaacct
     2461 tttggttatt cctttgaaga gaacaatccc gttcacccaa gtgaatcaca tgtccatgct
     2521 catcacctag gatttgaacc tcaatgtgcc gagctggata gataacccgt tctatgtaca
     2581 tggcaccatt gccataattg gccttggcct cactagaggc agtttcaaag gcagaaacga
     2641 ggtcatctgg tttttcaacc ttacgaatcc ctttaccacc tccacctgct gaagccttga
     2701 gcataacagg atagccaatt ttttcagcaa caatcaaagc ttcttcagag ttatgcactt
     2761 ctccatctga acctggtata acaggcacac ctgctttaat catctgagca cgcgcattga
     2821 tcttatcccc catcatatcc ataacatgac cagatggacc gataaacttg atacctactt
     2881 cttcacacat ggtcgcaaat ttggaatttt cactgagaaa tccaaaacca gggtgaatag
     2941 cttctgcctc agtcaagact gcagctgata gaactgcatt aatattgaga taagactctg
     3001 ttgccttgcc aggaccaata caaactgctt catctgccaa aagcgtatga agagcttcct
     3061 tatcagcagt tgaataaacc gctaccgtcg caatccccaa ttcacgtgcc gcacggataa
     3121 tacgaaccgc aatttcacca cgattggcaa ttaaaatttt tcgaaacatg gagaacctcc
     3181 ttagttccca attgcaaaag taagggtacc actggctgca agcttgccat ccacttcagc
     3241 ctttgcttca accacagcta tggtgccacg acgttttaca aaagtcgctg tcataaccaa
     3301 ttggtcgcct ggtacaactt gcttcttaaa cttaaccttg tccataccag cgtaaaagac
     3361 cagttttcct ttattttcag gttttgataa ctccaacaca ccggcagttt gcgccaaggc
     3421 ttccataatc agaacacctg gcataactgg gtattgagga aagtggccgt taaagaaagg
     3481 ctcgttgatg gtcacatttt tgatagcaac aatggtatcc tcgctcactt ccaagacacg
     3541 gtccactaga agcataggat aacggtgggg aagggcttct ttgattccct gaatatcgat
     3601 catttgatac gtaccaatcc tttaccaaac tcaaccattt cttcgttaga gacgagaatt
     3661 tccgttacca caccatcctt aggagctggg atttcattca tgactttcat ggcttcgata
     3721 attaccaatg tttgaccttt tttgacacta tcaccaactg taacgaaggc aggtttatct
     3781 ggtccagcag ccaagtaaac cactccaaca agtggactct ctacaagatt tccctcagta
     3841 gccacacttg cttcagctgg agctggaact tcttctgcta cagtctctgc tggagcagat
     3901 gtaggagcta ctggactcgg tgttgctaga acgggtgctg gagcgacttg agttgcaact
     3961 tcaggcacag gtctcgcttc attcttgcta aactgcaact catccgtccc atttttataa
     4021 gaaaattctc tcaaacttga ctggtcaaat tgagtcatca agtctttaat atcgtttaaa
     4081 ttcatactta tctattctcc caacgtttga aagcaagaac tgcattgtgg cctccaaaac
     4141 caaaagtatt tgaaatagcg tatggaattt ctttctccaa gccttgtcca taaacgacat
     4201 tagcttcgat ataatctgat acttcacttg tcccagctgt cattggtaca aagttatgac
     4261 gcatagcttc gatggtgacg atagcttcta ctgcacccgc agcccccagc aaatgtcctg
     4321 taaaagactt ggttgatgat acaggtactt ccttaccaag aacagctacg atagctccac
     4381 tttctccttt ttcattggca ggagttgacg ttccgtgagc attgacatag gctacttgct
     4441 ctggagaaat ctcagcttct tccaaggcta gtttgatggc cttgacagct ccctgacctt
     4501 ctggatgtgg agaagtcatg tggtaggcat cacaagtatt tccgtaacca accacttcag
     4561 ccaggatagt agctccacgt ttttcagcgt attcaaggct ttctagaacc aacatccctg
     4621 aaccttcacc cataacaaac ccattgcgat ccttatcaaa tgggatcgaa gcacgagttg
     4681 gatcctctgt agtagagaga gctgttaagg cttggaaacc agcgatggca aaaggtgtga
     4741 tagaagcttc tgttcctccc accaacatca catcttggaa accaaactta atggagcgga
     4801 aggcatcccc aatcgcatca tttgatgaag agcaggcagt attgatagat ttacaaacac
     4861 cgtttgcacc aaaacgcatg gctacattcc cagaagccat atttggtaaa gcttttggaa
     4921 gagtcattgg tttgacacgt ttgggtcctt tttcatgaag gcgaagtacc tgatcttcaa
     4981 tttccttgat tccaccaata ccagatgcaa cgataacacc aaaacgatcc ctattaagag
     5041 cctctacatc aagattggca tgatttacag cctcttgggc tgcatacaag gcatataaag
     5101 aatagttatc aaaacggttg gtatcttttt ttataaagta tttatcgaac ggaaaatctt
     5161 ggatttctgc cgcattatgc acatcaaagt cactatgatc aaattttgta atgccaccaa
     5221 tgccgatttt cccagttgct aaactattcc aaaattcttc tggtgtattt ccaattggag
     5281 atgttactcc ataacctgtt accactactc gatttagttt cattcttttc acctctagct
     5341 ttcgctacat acttaagcca ccatcaatgg caaccacttg accagttaga taatcttggc
     5401 ctgctaaaaa tactgtcaaa tctgcaacct gctctgcctg cccaaattct ttcatcggaa
     5461 tctgagctag tgtagcttcc ttaatcttat ctgataagat agctgtcata tcagactcaa
     5521 tcattcctgg agcaatcaca ttgactcgta tattccgact agcgacctcg cgtgccacag
     5581 acttggtaaa gccaatcaag ccagccttag aagcagcata gttagcttga ccaatattcc
     5641 ccatcaaacc aacaacacta gacatattaa tgatagcacc ttctctggct ttcatcatcg
     5701 gtttcaagac tgattgtgtc atattaaagg caccagtcag attgaccttg agcacttttt
     5761 caaaatctgc ttctgtcatc ttgagcataa gagtatcttg ggtaatccct gcattgttga
     5821 ccaaaacatc tactgaaccc agttctgcaa tagcttgatc aatcatacgc ttagcgtctg
     5881 caaaatctga tacatctcct gaaatgggaa ccaccttgat accatagttt gaaaactcag
     5941 cgagcaattc ttctgagatt gccccacgac tgtttaagac aatgttggct cctgcttgag
     6001 caaacttgtg ggcgatggca agaccaattc cacgactcga acctgtaata aagatatttt
     6061 tatgttctag tttcattttt ttcctttcaa aacttctact tattttagtc tatttttcta
     6121 aaagtgctac taaactcgct tgatcttcca catgagctaa gtgagcagtt tgatcaattt
     6181 ttttaacaaa acctgacaag actttccccg gtccaatctc gataaagttg cttatgcctg
     6241 cttcttgcat gaccccaata ctttcataga aacgaacggg ttccttgacc tgacgcgtca
     6301 agagctgagc aatgtcctct ttttgcatca cagtagcttc tgtattgccg actaggggac
     6361 aagtaaaatc tgaaaaactt acctgagcta gagtttcagc tagtttctgg ctagcaggtt
     6421 caaggagagc ggtgtgaaag ggacctgaca ccttaagagg aatcaagcgt ttggcacctg
     6481 cttcttgcaa aagttcaacc gctcgatcaa ctgcaaccac ttctccagca atgacgattt
     6541 gtgcaggtgt gttatagttg gctggagtaa ccactccaag ttcagaagct ttttgacagg
     6601 cttcttcaat gacctctact ggcgtattga gaactgctac catcttgcca gagtcagcag
     6661 gagccgcttc ttccatatag gctccacgct tagctaccaa ggcaaccgca tcttcaaaat
     6721 ccaaggcgcc gcttgccacc aaggcagagt attctccaag agacaaacca gcaaccatat
     6781 caggctgata gcccttttct tgcaataaac ggtagatagc aaccgaagtc gctagaatgg
     6841 ctggttgcgt atagcgggtc tgattgagtt tgtcttcttc cgtatcgatg agataacgta
     6901 aatcataacc gagcacctga ctcgctcgat caatcgtttc tttgacaacc ggatactgat
     6961 catagaaatc ccgtcccatc cctagatact gggcaccttg accagcaaat aaaaaggctg
     7021 ttttagtcat ttcttacaac tcctgcccag cgagaggctt cttcttgaat tttcttagcg
     7081 gctccgtaat acaaatcttt taggatttct tcagctgttt cttctttaga aacaagccct
     7141 gcgatttgac ctgccatgac agagccacca tccacatcac cgtgaacaac tgctttggct
     7201 agggcacctg ctcccatttg ttcaaagatt tctaaatcag gatcttcctg cttaaaggca
     7261 tctttttcag ccagttcaaa atctctagtc aactgatttt taatagcacg aacagcatga
     7321 ccaaagtgct gagctgaaat cgtagtatca atatcccttg cttttaaaat tttctccttg
     7381 tagtttggat gagcattcga ctcttttgca actacaaacc gtgtccccac ctgtacagcc
     7441 tctgcaccta gcataaagcc agccgcagca ccttcaccat ccgcaattcc tcctgcagca
     7501 ataacaggaa tagatatagc tgtggctacc tgtcgcacca aggtcatggt tgttaattta
     7561 ccgatatgcc ccccagcttc cattccttcc gcaataacag cgtctgcacc gattttttcc
     7621 atgcgtttag ctaaagcgac actaggaaca acaggaataa cgattatccc agcttcatgg
     7681 aaacgttcca tatacttgct tggatttcct gctcctgttg tgacaacttt aacaccttct
     7741 tcaataacga gatccacgat gtcttccaca aagggagata agagcatgat gttgacccca
     7801 aagggtttat cagtcaatga tttgatttta tcaatattgg ccttgacaac ttctttcggg
     7861 gcatttcccc caccgataat tcctaatcct ccagccttgg aaacagcccc tgccaaatca
     7921 ccatcagcaa cccaggccat ccctccttgg aaaataggat agtcaatctt caataattct
     7981 gtaatacgcg ttttcatagt gcctccaacc ttccttgctt acgtaatagt tcgatttcac
     8041 cataatttga cagtcaaact attacctaaa caagagggag tgggtttctc cctactcctt
     8101 ctactaatat tctgcttatt ttgcttgctc ttcaacgtaa gcaaccaagt caccaactgt
     8161 tttcaagtca ttttctgctt cgatttggat atcaaaagca tcttcgattt ctgagattac
     8221 ttggaacaag tccaatgaat ctgcgtccaa atcatcaaaa gttgattcaa gtgttacttc
     8281 tgatgcgtct tttccaagtt cttcaacgat aatttcttgt actttttcaa atactgccat
     8341 gataggactc ctttaaaata aatagttttt ttataacaat gtgttcacca catgattacc
     8401 taaattgtaa gaatgagcgt gccccaggtc aagcctccac cgaagcctga tagaagaaca
     8461 gtctggctac catctaaaga gatgagacct tgttctacac actctgaaag taaaatcggg
     8521 atactggctg cactggtatt gccatattcc atcatattgg ctggaagttt ggctcggtca
     8581 acaccaattt ttctagccat cttatccaaa atacggtcat tggcttgatg aagtagcaga
     8641 taatccaagt ctgtcacctc tataggagat tcatcaatag tctgcttgat agacttggct
     8701 acatctcgaa tggcaaaatc aaagactgtg cgtccatcca tcttcaaaaa cgaatctgca
     8761 ctttcttgat ctgaaaatgg agaatgcaaa cctgaatgcc cataagttaa acactcgctg
     8821 cgacttccat cgctattgag actctcagct aagaaatgct cttgctcgct agcttctaac
     8881 aagacaccac cagcaccatc tccaaacaac acagctgttg atcgatccga ccaatcgact
     8941 gccttagaga gggtttcact accaatcacc aagccttttt gaaagcgacc agaagcgata
     9001 aacttttcag cagttgaaag agcaaataca aatccactgc aagccgcggt taagtcaaaa
     9061 gcaaaggctt tattagcgcc aatattagct tgaacacgag cagctgtaga gggcatcatc
     9121 gaatctggag taatggtagc taggatgata aaatccagtt cttttcctgt tattccagct
     9181 tttgccatca gtttcttagc aacctctgta gccaaatcac tggtagattc tgttcttgaa
     9241 atatgccttt gtcgtattcc cgttcgactt gaaatccact catcattggt atccataatc
     9301 tgagccaagt cgtgatttgt aaccacttgc tctggcacat aatgagcaac ctgacttatt
     9361 tttgcaaaag ccattatttc aaatcctcca aaaattggta aagattagtc aagcctttac
     9421 ccatgacagc aatttcttcc tcgctcatgc catcaataat tttttctacc atggccttgt
     9481 ggaagcgttt atgcagtcta tgaatcaagc gacccttctt tgtcaaatgc agatgcacca
     9541 cacgacgatc ctgttctgac cgaactcgct caatgtagcc cttacgctct aaattgttca
     9601 aacttgtcgt aacagttcca agagttacca tcaactcttt tgacacttga cttggagtca
     9661 catctggagc cttaccgatg acatcaatcg tatgcatttc tttgatggag atatccttaa
     9721 aacgactacc tctcaagttc acttcctcaa ttacaaggac attgttaaat atagatgtta
     9781 aatattcatt gattcgttgg tagtccattt ttcatatccc tccttcttca aaaaactttt
     9841 acaatcaaaa catttgacag aaagaattat atcaaaattc aaagaatgat gcaagtattt
     9901 tttattttcc tgtaaattta ggtcttcttc tctccgaatg agctcgcact ccttctttga
     9961 aatcctctgt ttgagctaag gatttctgta ggttcagttc taaagtagcg taaccctgcc
    10021 agtctttaaa ctggctctcc caaaccaact tcttaatggc agcataggaa ttacttgaag
    10081 cacgtcttaa ttttttaaga agctgttctc tcgtcttttc aagtttttca gcttcagaaa
    10141 cgcggtaaac caacccccat tctagggctt tttctgccgt taaagcctct cctgtcatag
    10201 ctaattgagc agcacgcgtc acaccgatac tgcggctcaa gagatgaatt ccccctgcat
    10261 ctggagccaa accaacacca acaaaggctt ggataaactt agccttatcc gtcgccaaac
    10321 agaaatctgc cgcaacagcc atattcgctg cggcacctgc aacagcaccg tcaacttcca
    10381 ttaaaacagg tttggctatt tgcttgattt tataagaaat cgtattgacc aactctgcga
    10441 tttttgtcaa tgatggaata tcatcctcat ccactgcccg cttcatctct accaaatctc
    10501 ccccaactga gaagaccttt ccattggcat tgattaagat aaaatgcaca gctggatttt
    10561 cttctgccaa agtcagagct tctaaaatct cctcacacat gggaatatga aaaccatttg
    10621 cgacctcagg acggttcaag gtaaggattg ccaagtcctc ttcaagctga taaataatgt
    10681 gttccatcag ggctcctttt tattttataa gcagtttata ctcttcgaaa atctctttaa
    10741 accgcgtcag cttccatctg caacctcaaa acagtatttt gagctgactt cggctagctt
    10801 cctagtttgc tctttgattt tcattgagtg ttaaattatt tcactgtcaa agtatatctt
    10861 ttttaggagc agaaagcaag aaaaaatcga ctgaaagtgt ctcagccgat aagaaaggct
    10921 cgctttaggc tagaaagcat cttattttct tcattgaaaa aagcctttct ttctgctata
    10981 atcgtataaa atacttactt taggagttct tatgaaagtt gttaaatttg gaggtagttc
    11041 tcttgcctct gctagtcaat tagaaaaagt tttaaacatc gtcaaaagcg attcagagcg
    11101 tcgttttgta gtcgtttctg cgcctggtaa acgcaatgct gaagatacta aggttacgga
    11161 tgccctgatt aaatactacc gcgactatgt tgcgggtaac gatattagca agagccaaag
    11221 ctggattatc gaccgctatg ctgctatggt tagtgaattg ggactaaaac cagctgtgct
    11281 agaaaaaatt tctaaaagca ttcacgcctt ggccactctt cctattgaag aaaatgaatt
    11341 tctctacgat actttcctag cagccggtga aaataacaat gccaaattga ttgctgccta
    11401 ctttaaccaa aatggtatcg atgcacgcta tatgcaccct agagaagctg ggattgtggt
    11461 cacaagtgaa cctggtcacg ctcgcatcat tccatcaagt tatgacaaga ttgaagaatt
    11521 gacaaacacc aatgaagtcc ttgtcattcc tggtttcttt ggtgtcacta aggaaaatca
    11581 aatctgtact ttctcacgtg gaggttctga tattacaggt tctatcattg ctgctggtgt
    11641 caaagctgac ctctatgaaa actttacgga cgttgatggt atctttgcag cccaccctgg
    11701 tattatccac caaccacact cgattcctga gttgacctac cgtgaaatgc gcgagttggc
    11761 ctatgcaggc ttctcagtcc ttcatgacga ggctcttctt cctgcctacc gtggaaaaat
    11821 tcctctggtt atcaagaata ccaacaaccc tgaccatcca ggtactcgta tcgttctaaa
    11881 acacagtaat gatgaatttc cagttgtggg aattgctggt gactcaggct ttgtcagcat
    11941 taacatgtcg aaatacctca tgaaccgtga ggttggattt ggccgcaagg ttctgcaaat
    12001 cctggaagaa cttaacatcg gttgggaaca tatgccaaca ggtatcgacg atctttctat
    12061 cattctccgt tctcgccaac taactcccat caaggaagaa gaaatcctgc gtcagttggt
    12121 tcaaaaggct aaagtagatc atgcagaaat cgaacacgac ctttctatca ttatgattgt
    12181 tggtgaaaaa atgaagagcc atatcggagt gactgctact gcgacacgcg ctctatctga
    12241 aaacaaaatc aacatccaga tgatgtctca aggttctagt gaagtttcta ttatgtttgt
    12301 tgtcaataaa gaccaagaga aagcagcaat taaagccctc tacaatgcct tttttggaga
    12361 aagtaaggaa gactaagcat ggctcaatca cttaacaaaa cagtactcct cagtacgaca
    12421 ggcacttcct acctctctat cgctgggaaa gttgggaaat tccttgtcgg agatcaggct
    12481 ttggaatttt acccagatgt caatgtcgaa caatttatcc agattccttg gagccatatc
    12541 aatcagattg gagccaatgt cactggacgc aaaatcagcc gccacttcga agtctttaca
    12601 gacaaaggaa aattcctctt tgcttcaaaa gactcaggtg ccattctcaa aattgcacgc
    12661 aaaaaactag gcaatgacaa ggtcgtcaaa cttccgaccc tgattcagac aattagccaa
    12721 aaatttaaaa atctatttgc aaaaaagtag aaactttagt ataatcatag caacggataa
    12781 gtaggttatc ttcttctttc agaaagtctg cgggtactgc gagcagatag gagggatagg
    12841 tgaaattcta ccgttagtaa caattacata cacaatcaag tgcacacctg tgaagttgga
    12901 tggaaccgtg gccctgccac tccaacgttt tgtcaggcgt gcttttttca taaaggagtt
    12961 cttatgttag atatcaaacg tattcgtaca gattttgaag ctgtcgcaga aaaattagct
    13021 acacgtggtg tagatgctgc tgtcttgaat gaaatgaaag aaatcgatgc taaacgtcgt
    13081 aacatcttgg tcaaggttga aactctcaaa gcagaacgta acacagtttc tgctgagatt
    13141 gcccaagcta agcgcaacaa ggaaaataca gatgacaaga ttgctgccat gcaaaatcta
    13201 tctgctgagg ttaaagcctt ggatgctgaa ttggcagaaa tcgatgctaa attgacagaa
    13261 tttacaacga ctcttccaaa tatcccagct gacagcgttc ctgttggggc tgacgaagac
    13321 gacaatgtgg aagttcgccg ttggggtact ccacgcgagt ttgacttcga acctaaagct
    13381 cactgggatc tcggtgaaga ccttggtatc cttgactggg aacgcggtgg taaggtaaca
    13441 ggcgctcgct tcctcttcta taaaggcctc ggtgctcgtt tggaacgtgc tatctacaac
    13501 tttatgttgg atgaacatgg aaaagaaggc tatactgaag tcatcacacc ttacatagtc
    13561 aaccatgatt ctatgtttgg tactggtcag tatccaaaat ttaaggaaga tacttttgaa
    13621 ctcagcgata ccaactttgt cttgattcca actgctgaag ttcctctgac aaactactac
    13681 cgtgatgaaa tcttagacgg caaagatctt ccaatctact tcactgccat gagtccgtca
    13741 ttccgttctg aggctggttc tgccggtcgt gatacgcgtg gcttgatccg tttgcaccaa
    13801 ttccacaagg ttgaaatggt caaatttgcc aaaccagaag aatcttacga agaattggaa
    13861 aaaatgacag ccaacgctga aaacattctt caaaaactca accttccata ccgtgtcgtt
    13921 gctctctcta ctggagatat gggcttctca gctacgaaga cttacgactt ggaagtgtgg
    13981 attccagcac aaaacaatta ccgtgaaatc tcaagctgtt caaacacaga agatttccaa
    14041 gcccgtcgtg cccaaatccg ttaccgtgat gaagcagatg gcaaggtgaa actccttcat
    14101 accttgaacg gttctggact tgcagttgga cgtacagtgg ctgcaattct tgaaaattac
    14161 caaaatgaag atggttctgt gaccatccca gaagcacttc gtccatacat gggtggagct
    14221 gaagtcatca aaccataaaa aataaggttt agctatttct agctagacct tttttcgtaa
    14281 ccaaatcaga taagcaccta gtacaaagaa taaaatagtt aggcatataa tggtttcagc
    14341 caataccagg taatccagaa atggaagttt caaaattccc tgagccatct tgagcgaggt
    14401 cgctgtgata atggttggga aggtgagggc tgagaaggct ggttgaaaac cttgttttaa
    14461 aatgttgggc agacgagtta aaacaaagaa aaagaaggat tgagaagcca aaatcatgac
    14521 aatcaagacc caagtcggca ggctggttcc tcctactcga actagagaag ccaagagtag
    14581 agagaaagga gcacagtaga ttccttcttg tccaagcaag gctagtggga gtggatgttt
    14641 ctttaaatcg ctataaataa ggggatagag atagaaggtc aagagaaaac caaaactcaa
    14701 ggtcgcatag gcaatttcga taatacctac cagaggatag gtcaaggcag ccactgctat
    14761 ccccacatag agaaccgtcc agcttggagt ggcatgaacc ctccgctctg gacaagcaaa
    14821 cttgatggta aaaccagcaa tcaaggtcaa atccaagaga aatgaaaacc accaaatccc
    14881 ttgtgctacc aaaggaagat aagagaatac gcgaaagaca taggtcgata aaatcatccc
    14941 agccatagga aaggttgcca ttcctgacaa aagagggggc ttggtcaatt cttgcttggt
    15001 ttctttccaa ttaaagagat gcagaattag aaagtaaatc cataaaacca aaccagtcag
    15061 actaaaaaga tgggatagaa ctggcaacat atctaaaata agatttccag ctcctgccaa
    15121 acctagcaaa caacctgaaa atactaaggg gagttttttc atcctaacct ccaataatca
    15181 tgttagtttc agtataacat aaaagcgctt aaatgaggat ttaaaaaaac gaagtccgat
    15241 tatttcagac ttcattttac tcagatatga attaggcata aggttgcaat tctggattaa
    15301 ttggtgtatt agctaagttg ttggcatagt tacagaggat tgctaggctg acaccgaaaa
    15361 ccacatccaa ggcattttgt tgagtgtagc cagcttctaa aaactcagac aaggcttcat
    15421 ctcctacacg acccttggta ttgataactg ccaaggtaaa cttagctagg gtatccaatt
    15481 taggatctgt ttcaattgga gtacgattgc gaagagcttg aatcaagtca tcattcatct
    15541 ggatttgttt gatggaaaag gctgtgtgac ctgcgacaca gaaggcacaa ccattggtca
    15601 cggctgccgt gatttgcacc acttcacgct caacgggtgt caggctgttg cgacggtgga
    15661 tagatgagac aatttggtag gcttctaaaa cagtcggggc attggccaag agaccgatta
    15721 ggttgggaat atagccattg ttgtcttttt ctactgtttc aagaatttct ttcacttctg
    15781 ctggtgctga ctctactgta tggatagtaa atgttgtcat aagatacctc ttttcttatt
    15841 attgacacta atattattgg aaaatcttat aaaatcctga ttcctaagtt tatctaagat
    15901 aaagctttat tctctcataa gattttcgtt gttatattag tttatcacac ttccaatcac
    15961 ttgcataata tatattatat atcaggctga taaaaattat ttataggcaa aaaaatcaca
    16021 cgagctgtgt gattccatta tttgtcaaaa tactttttag tttcagcaat aacgactggc
    16081 gacaagacca agagggcaat caagtttggc agagccatca aggcgttaac gatatctgcg
    16141 ataatccaga ccatatccaa ctcgataaat cctcctaaca agaccatgag cacaaaaacc
    16201 acacggtaga gccagataaa gcgaacccca aagaggaact caaaacagcg ttctccgtaa
    16261 tagttccaac ctagaatcgt tgtaaaggca aaaagtacaa ggaagatggt caagagggca
    16321 ggcccaaagt gtgaaaagac tgttgagaaa gctgactgag tcaaggcaac cccattcaag
    16381 tcaccactcc aaactccagt taccaagatg gtcaaaccag ttagagtaca aatgatgagg
    16441 gtatcaataa aggttcctgt catggaaatc aaaccttgct ctactggttc atttgtcttg
    16501 gcagctgcag ctgcaatagg agcagaaccc agaccagatt cgtttgagaa cacaccacgc
    16561 gccacaccat tttgaatagc catccgaacg ctagcaccag caaatccacc taccgcagca
    16621 aggggactaa aagctgaggt aaagactaaa gcgattgtgc cagggatttt tccgatatta
    16681 aagaaaataa ctataagagt tcctaagata taaatgatgg tcataaaagg aacaacagta
    16741 gttgaaacct tagaaataga cttgagtcca ccaaagactg caatcgctac aaagacagac
    16801 aagacgagag ctgtgatgac tggcgaaatc gtcgttgtat tttggataga ttctgtaatc
    16861 gagttgactt gggtgaaggt tccgattccc aagagagcaa ccaatactcc tgctactgca
    16921 aacaaaacag caagtggtcg ccacttttct cccatcccta gaaggatata gtgcatggga
    16981 cctcccgcta ctgcaccatg gtcgtccttg gtgcggtatt tgatggccaa gagtccttcc
    17041 gcatacttgg tagccattcc aaagaaagcc gccatccaca tccaaaatag agctcctggt
    17101 ccaccaacct tgatagccgt cgcaactcct atgatatttc ctgttccaac agttgatgcc
    17161 aaggctgtac acagagctgc aaaactggat acatcaccat gtcccttatc ctggataaaa
    17221 ataagctgaa aggccttggg cagacgcaaa acctgcaaga gtcctagccg catggttagg
    17281 taaatccctg ttccgaccaa taaaatcaag aggggcggtc cccaagcaaa atcatcgatt
    17341 gatttaagca attctaacat ttccttctcc tatcgtttca accccaaaag aaagagcaca
    17401 tgcaagatac atgtactctg gaatgcttag ataaatgcta aaaagcggtc tatcctagct
    17461 ctgtcctttt acctgagagt ttgagcagtt gcctgccttg ccccttcggt gcctttacgg
    17521 tctctccaga gttccgtcca tttacagtca tggaaaatca aacgattccc cacttctatt
    17581 aaacttcatt cggtgttggt atttaattga ttctaatttt acaaaaaatg ttggcttttg
    17641 tcaatgtgtt tattagtaaa aattagttca acagttttta ctttataaag tccagaatac
    17701 tgctatcctt taaaagtgac aatagtcgca ccactgcctc cagcattttg tggggcatag
    17761 ccgaaactct tgacatgttt gtttctttgc aagtatttgg taactccttc acggatgact
    17821 cctgttccga taccatggat gatatcaact tgagccatat tgttaagcaa ggcttggtcg
    17881 atgaaggtat ctagctcatt catggcttct tcatagcgct tgcctcgaag atccagtcta
    17941 gcttgaggtc ctcgcccaga agttcgtttc acaacattga cctgtttctt cttgactggt
    18001 ttttcttgct gggcttgaac aagatcaaac tctttctctt ccaaggtcat cttaatcaag
    18061 ccaacttggg cttcccagcg gccgtccttg agttgactgg tcaaggtacc acgctgacca
    18121 taactgagaa ccacgatatc atctcccacc tttggagctc gttttttctt ggccttttga
    18181 aggaccttgt ttttagacaa gtccactttt tcaggagcca attttttcaa cttggccttg
    18241 gcttcaatga tttcgtgggg cttgagttgg gatttactgt ggagattttt gagaatctgg
    18301 tcactttcac ttagggccat atccacaatc tcagcagcct gttcacgcgc cttgttaagc
    18361 tcggtttcct tttcacgatt aagctcgttg tagagttttt ttagcgcacg gttcatcttg
    18421 agattttctt gctccacctc acggatattg tccaaacgtt tgcggctttc cagcgtctgc
    18481 tcttctaatt gctcaatgat acgattgacg tcattgtcct gatcgatctg ctgactggca
    18541 tctcctacga taacttcaga taggcctaga cgtttggcaa tttcaaaggc attacttcgg
    18601 ccaggaacac cctgcataaa gcgataggtt gggcgaagag ttgcagtatc aaactccata
    18661 ctggcatttt gcacaaaggc tgtctcaata ccgtaggcct tgagttctgg atagtgggtc
    18721 gtcgccatgg tcttgatttg acgcaggcga aggtcctcca gaatagccat ggcaagggct
    18781 gctccctctt ggggatcagt accagccccc aactcatcca aaagtaagag tgaatgttgg
    18841 ttgaccttgc caagaatatc cacgatattg gtcatatggc tagagaaggt agacaagctc
    18901 tgctcaatag actgctcatc tccaatatca gcaaagattt cttcaaaaat accaacacga
    18961 cttcccttgt ctgctaaaat cggcaatcct gactgggcca tgacctgtgt caagcccaga
    19021 gttttgagca tgatggtctt cccacctgta ttgggacctg taatgacaat agctgttaaa
    19081 tcttgaccaa aatagacatc atttgcgacg gcatttttga ccaaaggatg gcagacatgg
    19141 agcagttgaa tctcttgatt ttctgacagc tgaggcacga ctgcttgtct ttcttggata
    19201 aatcgaacct tggcacgaat caagtccaga tgaccgataa tccaagcgtc attagcaatc
    19261 tcagccgcat gagggcggac acgctcagaa atttcttgga gaatgcgaag catttcatag
    19321 cgctcatctg ctcgcagact agcaatttct tcgctcagtt tgactacctc acgtggttcg
    19381 atatagacgg tgtttccact agcagaaata tcatgaacga cacctgcaat cttattgcgg
    19441 taggtgtttt tgactggtaa aacctgacgg ccatttctgc tagcaacaat tccttccgtc
    19501 aacatctgcg ctttttgctt gagtaagtct tgtaaaacat cgcgcacctg actctcgcta
    19561 tcatgtattt ttcgacggat tcgcgccaat tcttcactgg caaaattttc aatgaaaccc
    19621 gcatcattaa aggcctgaag atttccttgt aattgcggaa aatcatgtaa tttctcaaac
    19681 caaagggcta attcttccaa gctgacattt tccagattgg cgtaaaaatt ttgaagttct
    19741 cggctggcaa gaagcacgcg tttcaagagt aggaactcct cgatattgag atccgctccc
    19801 atctccaacc tcttgcagac tcctgcaatt tccttagttg agagaatagt aaaatgcggt
    19861 tgctcgacga aaagagcctg catttctttc atctcagcaa aagcctgttt gattttatct
    19921 gctttggcag tcggagccag ctgtctcaat tgctccaagc cctgctcggt caacaaatga
    19981 ggctcaaaca aggccttgac cttatcgaac tctaatgttt ctaatatttt cttattcatc
    20041 tttatttcct tgtctttgaa tgtctaggtg tggtagcttt ttacattctg atagattcga
    20101 gtcaaatctg taaacaaagg gctaggaaaa ctcctgccct ttttatccga ttaaatttgt
    20161 cacccagatt tgtttgagcc aactggttgt tatcggtatg ctctggatga tgtgttttgc
    20221 gacgatactc ttttcaagag gattttgtat aactgccatg gggatggtcg ccaagattgt
    20281 caaggccatt tgcaagacaa ataaggtcac caacatggac aagatacctg ctgaaacttg
    20341 gaacaactta ccacccagtt ttttgctagg aatcaagtgt aagagaagac caagcaaacg
    20401 accaatacta tagacaatcc caaatacaag caagtagccg atacctgcat aaaagacctt
    20461 atccagctga aagagttgat ccgatgggaa aaagaaagtc ccctgacctt cctgcgaatt
    20521 tgcataaggg agcaataaat ggaattgctc tccaagcccc ttataaaact ggccagccat
    20581 aaaagccgat gccatggctg aaatcaggta ataaacctgt aagagcaggc ctctccgata
    20641 gccgatataa aatccccaaa ccaagaccaa tagaagaagg aatgaaatca taaggaatcc
    20701 tcaatcttgc tctgttcttg cttacaagtc acaagcttgt gacggagttc ttctagctct
    20761 tgctccttat cgtcaaattc aatctcacgg ctgagctgag ttgataaaca gttgactgcc
    20821 aacaaaagag cgattgtttc atcatctgcg ctaggcattt gttctttaat tgcttggtat
    20881 ttttctgtcg caaccttagc gatttcctcc ataaaaaggt tatcatgttc gcttgtcaag
    20941 gttaacgttt ttttcccgaa tgtaaatttg aatcgattta gatttgccat aaaattcacc
    21001 tcacgatatt ataccaaaat tcgctaattt tgtcagtttt tacaaatttt actgcttttg
    21061 tggtacaata gaaactatgg caagtatcac actcacacca agcgaaaagg atattcaggc
    21121 ttttcttgaa cactatcaaa ccagtctggc tcctagcaag aatccctata tccgctactt
    21181 tttgaaacta cctcaagcaa cggtttctat ctatacttct ggaaaaatct tgcttcaggg
    21241 tgaaggggct gaaaaatacg ccagtttctt tggctatcaa gctgtagagc aaaccagcgg
    21301 acaaaatctt cctttgattg ggacagatga ggtgggaaat ggttcctact ttggtgggct
    21361 tgcagttgtg gctgcctttg tcacacctga ccagcacgac tttttacgaa aactcggtgt
    21421 gggggattct aagactctga ccgaccaaaa gatccgtcag attgctccta ttctcaagga
    21481 aaaaatccag caccaggcac tccttctctc acccagcaag tacaacgagg tcatcggaga
    21541 ccgctacaat gctgtttcgg ttaaggttgc cctccataat caggctatct atctcctcct
    21601 tcaaaaaggt gttcagcctg agaaaattgt gattgatgcc tttaccagtg ctaaaaatta
    21661 tgacaagtac ttggcacaag aggccaatcg tttcagcaat cctatcagct tagaagaaaa
    21721 ggctgagggc aaatacttgt ctgtcgcagt ttcttctgtc attgcgcgtg atctctttct
    21781 ggaaaatctt gaaaatctgg gacgagaact gggttatcag cttccaagtg gagctggaac
    21841 ggcttctgac aaggtggcta gccagatttt gcaagcctat ggtatgcagg gactcaactt
    21901 ctgcgccaaa ttgcacttta aaaacactga aaaagcgaaa aaacgcttag aaaggtaagt
    21961 tatgaattca tttaaaaatt tcttaaaaga gtggggactg ttcctcctaa ttctgtcatt
    22021 actagcttta agtcgtatct ttttttggag caatgttcgc gtagaaggac attccatgga
    22081 tccgacccta gcggatggcg aaattctctt cgttgtaaaa caccttccta ttgaccgttt
    22141 tgatatcgtg gtggcccatg aggaagatgg caataaggac attgtcaaac gtgtcatcgg
    22201 aatgcctggc gataccatcc gttacgaaaa tgataaactt tacatcaatg acaaagaaac
    22261 ggacgagcct tatctagcag actatatcaa acgcttcaag gatgacaaac tccaaagcac
    22321 ttactcaggc aagggctttg aaggaaataa aggaactttc tttagaagta tcgctcaaaa
    22381 agcccaagcc ttcacagttg atgtcaacta caacaccaac tttagcttta ctgttccaga
    22441 aggagaatac cttctcctcg gagatgaccg cttggtttcg agcgacagcc gccacgtagg
    22501 taccttcaaa gcaaaagata tcacagggga agctaaattc cgcttctggc caatcacccg
    22561 tatcggaaca ttttaagaga cctaagaggc cgagaatcac aaatctcagc ctcttcttct
    22621 atcgtgagaa gtgattgttt attgacaaat actcaatgaa aatcaaagaa caaactagga
    22681 agctagccgt aggctgctta aaacagtgtt ttgaggttgt ggatagaact gacgaagtca
    22741 gctcaaaata ctgttttgag gttgcagatg gaagctgacg tggtttgaag atattttcga
    22801 agagtataaa ataaaaacaa tcccaactct cacctattca tgcaaaggaa ttttatggaa
    22861 gtttattttt caggaaccat tgaacggatt atttttgaaa atcccagcaa tttttatcgc
    22921 atcctcctcc tagaaatcga cgatacggac gcagaggatt ttgatgattt tgaaatcatt
    22981 gtcacaggaa ccatggctga tgtaattgag ggcgaagact atattttttg ggggcaaatt
    23041 gtccagcact ccaagtatgg agaacaactg caaatcagtc gttatgatcg cgcaaaacca
    23101 actagtaagg gattggtcaa gtacttttca agtagccatt tcaaggggat tggtctcaag
    23161 acagctcaga aaatcgtaga tacctatggc gaaaatacca ttgatgaaat tttgcaacac
    23221 ccagaaaagt tagaaggcat cgcaggactc tctgccaaaa atcgcgaggc tttcgtctcc
    23281 actctccgtc tcaactacgg aacggagatg gttttggcca aactagccaa ctacggcatt
    23341 cccaacaaac tagcctttca gattcaagac ttttacaagg aagaaaccct tgatgtggtt
    23401 gaaaattatc cctaccagct ggttgaggat atcaagggtt tgggctttac aattgctgac
    23461 caactagctg aggaactagg catcgaaagt caggctcctg aacgcttccg cgccggtcta
    23521 gttcacagtc tttttcaggc ctgtatggaa acaggggaca cctatgttga agcacgggat
    23581 ttgctggaac aaacccttac tctccttgag tcttcccgtc ccgtggaact agaccccagc
    23641 caagttgccc aagagctctc ctacctgatc gaagaagaca aggttcagca gattgatacc
    23701 aagatctttg acaacagcct ctttttcgct gaggaaggca tccgcagtca cttggttcgt
    23761 atccttgaaa aaggaaaaca gaagagtcat gatttagaaa ccattcaaaa acatatcact
    23821 actatcgagg aagagctggg aattgagtat gataacattc aaaaacaggc tatctgtgac
    23881 gctatccaga acaaggtctt tatcctgaca ggtgggcctg gtactggtaa gacaactgtt
    23941 atcaatggaa tcatcgctgt ttatgccctt ttagaaggac ttgacttcag gaagaaaaac
    24001 aatctgccca ttcttcttgc tgctccaact ggacgagccg ctcgccgcat gaatgaattg
    24061 acaggtttgc ctagcgcgac catacaccgc cacttgggaa tgacaggtga cgatgatacc
    24121 agtcatctgg aagattacct agatgctgac tttatcatcg tggatgaatt ctctatggtg
    24181 gatacttggc tggccaatca actcttctcc aatatctctt ctaacagtaa gatcctcatc
    24241 gtgggtgaca gtgatcagct accttctgtc agtcctggac aggttctagc ggatctgctt
    24301 catattcctt tgattcctca gactcgcttg gaaaaaattt atcgacaaag cgaagaatca
    24361 accatcgtca ccctagctag tcagattcga cagggcatct tgccagctga tttcacccaa
    24421 aaaaaagctg accgttccta ctttgaaatt gctagtggcc atattcctgc cactattgaa
    24481 aaaatcttag atgccgccct cagaaatggt attcctgccc gtgatatcca agttctggct
    24541 cctatgtacc gagggacggc agggattgat gctatcaatc agctcatgca agacctgctc
    24601 aatcccccac aaaaagatca actcagtttt gaagctcctc agtgccacta tcgtaaggga
    24661 gacaaggtca ttcatttggt taacgatgct gaaatcaatg tctttaatgg ggatttagga
    24721 gctatcacag acctgattcc tggtaaatac accgaatcga aacaagacga gattgtcatt
    24781 gattttgatg gtaatgaagt ctcttacccc cgtaacgaat ggtacaagat tcgcttggcc
    24841 tatgccatga gtattcataa gtctcaggga agtgagttcc cagttgtcat cctaccgatt
    24901 actagtgcta gccgacgtat gctggagcga aatctcatct acacagccat tacacgtgcc
    24961 aaaagcaaac tcatcttact aggcgaatta caagccttcg actatgctac ccaacacatc
    25021 ggaactgccc gaaaaaccta tctgattgaa cgcttcagtg atctactgga gaatgttgaa
    25081 gaaaagcaac aagctgtctc tgaaacagtc acatcaagtg cctctgaaca atcctacatc
    25141 ctaaccgaag aaaactggga cagcattcca gccatgattg ggattacaga cacagacctc
    25201 aaagagattt ttggaaaata gtacatcaga aaacccacca attcaggtgg gttttctgtt
    25261 tattaagatt attttactgt tgctgtgctt gtgatcaatt caacagcttt tttgatagtg
    25321 atatcatgtt tcaacatgtc agctgaaagc aagttttgaa cttgtgcaac ttccatgttg
    25381 tagtctgctg ccaattgctc aacttctttt tggatttctt cttctgaagc atcaaatcct
    25441 tcagctttgg caactgcttc gataacaagg ttagtcttag tacgtgactc agcttctgct
    25501 tggtattggt tatgaaggtc ttcttgagta gttccagtga tttggaagta catgtcaggg
    25561 ttgatccctt gacgttgcaa gttcccaagg aattcattta ctgaacggtg aacttcttcg
    25621 tggatcattt cttctggaag ttctacgatt tcagcgtttt ctacagctgt atcaattgct
    25681 gcaccttcaa ctgcatcttt gtaagcttct tctttagcag cagccaattc tttgcggtat
    25741 ttttctttca agtcagcaag tgtttcaact tcttcatcaa tgtcttttgc aagttcatcg
    25801 tcaagagctg gaacttcttt agcttttact tcgtggatag ttgtcacgaa ttgagcttct
    25861 ttacctgcaa ggtcttctgc ttggtagtct tctgggaatg ttacgataac atcaacggtt
    25921 tcgccagctg agtgacctac caattggtct tcgaaaccag ggatgaattg acctgaacca
    25981 agtccaagtg agaagttttc accttttcca ccgtcaaatt caacaccgtc gatagaacca
    26041 acgaagtcga tcacaacagt gtcgccgttt tcagcagcag cttccttgat aaccaattca
    26101 gccaggttgt tgcgttcgcg ttcgatacgc tcttcaacat cagcgtcagt tacttctttt
    26161 tctacatcaa ctgatacttc aaggtttttg tagtcaccca attttacttc aggttttgta
    26221 acgacttcag cagtgataac ccagtcttga cctttttcca ttgaagttac gtcaattttt
    26281 ggttgggcaa ccacttcaag accagcttct tttacagctg cttcataagc gtttggcaaa
    26341 agagcgttca taacgtcttg gtaaagtgat tcttcaccaa attttttatc gaagatagga
    26401 cgtggaaggt gacctttacg gaaacctgga acattaagag atttcttcac tgacttgaag
    26461 acacggtcca attctggttt gatttggtct tgagagatag tgaaagtcaa gacaccacgg
    26521 tttgtttctt tgttttcaaa tgatacagac attctgtcat ttctccttaa aattt
//
LOCUS       DAVLDI010000029        25444 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLDI010000029 DAVLDI010000000
VERSION     DAVLDI010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25444
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.029"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(155..1141)
                     /locus_tag="VXD01_001237"
     CDS             complement(155..1141)
                     /locus_tag="VXD01_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0601644.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1151..1951)
                     /locus_tag="VXD01_001238"
     CDS             complement(1151..1951)
                     /locus_tag="VXD01_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV0601645.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2204..3046)
                     /locus_tag="VXD01_001239"
     CDS             complement(2204..3046)
                     /locus_tag="VXD01_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0601646.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3048..4340)
                     /locus_tag="VXD01_001240"
     CDS             complement(3048..4340)
                     /locus_tag="VXD01_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0601647.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4451..5722)
                     /locus_tag="VXD01_001241"
     CDS             complement(4451..5722)
                     /locus_tag="VXD01_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0601648.1"
                     /translation="MSSKFMKSAAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6272..7789
                     /gene="malQ"
                     /locus_tag="VXD01_001242"
     CDS             6272..7789
                     /gene="malQ"
                     /locus_tag="VXD01_001242"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV0601649.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            7815..10073
                     /gene="glgP"
                     /locus_tag="VXD01_001243"
     CDS             7815..10073
                     /gene="glgP"
                     /locus_tag="VXD01_001243"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV0601650.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11118..11645)
                     /locus_tag="VXD01_001244"
     CDS             complement(11118..11645)
                     /locus_tag="VXD01_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601651.1"
                     /translation="MLIVSAIPSVSAVYASEQVSQIETNMELQPVTSLTEEQINTLAN
                     EIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGITVNQMGALLDTAIALA
                     LGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALEFAMNLLSPGTYLAQL
                     WDKNDAIPNNGRINF"
     gene            complement(12579..13427)
                     /locus_tag="VXD01_001245"
     CDS             complement(12579..13427)
                     /locus_tag="VXD01_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0601652.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13579..13857
                     /locus_tag="VXD01_001246"
     CDS             13579..13857
                     /locus_tag="VXD01_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601653.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13859..15922
                     /locus_tag="VXD01_001247"
     CDS             13859..15922
                     /locus_tag="VXD01_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0601654.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(16000..17256)
                     /locus_tag="VXD01_001248"
     CDS             complement(16000..17256)
                     /locus_tag="VXD01_001248"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV0601655.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17398..19860
                     /locus_tag="VXD01_001249"
     CDS             17398..19860
                     /locus_tag="VXD01_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0601656.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMTKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNEHFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSRARR"
     gene            19925..20836
                     /locus_tag="VXD01_001250"
     CDS             19925..20836
                     /locus_tag="VXD01_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV0601657.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            21066..21764
                     /gene="dapD"
                     /locus_tag="VXD01_001251"
     CDS             21066..21764
                     /gene="dapD"
                     /locus_tag="VXD01_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV0601658.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEHDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21832..22962
                     /locus_tag="VXD01_001252"
     CDS             21832..22962
                     /locus_tag="VXD01_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV0601659.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22974..23513
                     /locus_tag="VXD01_001253"
     CDS             22974..23513
                     /locus_tag="VXD01_001253"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV0601660.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGRTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23497..24174
                     /locus_tag="VXD01_001254"
     CDS             23497..24174
                     /locus_tag="VXD01_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV0601661.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            24188..24265
                     /locus_tag="VXD01_001255"
                     /pseudo
     CDS             24188..24265
                     /locus_tag="VXD01_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(24475..25410)
                     /locus_tag="VXD01_001256"
     CDS             complement(24475..25410)
                     /locus_tag="VXD01_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601662.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDEKFKDKATLETNVKEITKQIDFIKKVDETFKQENLEE
                     TLKSLNDLVDKYQKQIELLKKEEEKAAEKAKESSSQSNSSSGASNESYNGSSNSNVDY
                     SSSEQTNGYSNNYGSQSYSGSGDSSTNGGSSEQYSSSNSNSGVNNGYYKKYKNIGADG
                     HVSYTYDNESNGDVFDENWNYLGNTGGGIAEPPQR"
BASE COUNT         7468 a         4640 c         5521 g         7815 t
ORIGIN      
        1 ctttgatttt cattgagtat aaaaagatct tgggaaaaga ctcaatttca gtagaaaagg
       61 aagtaaatct tcccacaata aaacgcatag tatcaagttt tttcaatacc tgatagtatg
      121 cgtttttgct tttaacgact ctttgcccag tctcttattt ttcgataatt ttgtgggcga
      181 tcaattgacg gtaacaaatt tgtttattgt ttttattatc attaataatc tggagaatag
      241 tttcaaggga aacacgacca agctctaaac tattgatatc gacataggct gccaagttga
      301 gcttgggatt aaccgagtca aagctgagaa cagggacatc cagctggtgt ttggcaatat
      361 agttacaaac accttcagct aggaggctat cggttgtgat gatagcgtca atttgtggat
      421 cgtgcttgaa taatcgcttg ctaaatttat agcccttttc ttccagaaac tcgtcggcaa
      481 agtagatgcg attgttgtca gtggtaagtt tgtaatgttt aagcgcctgt tcatagcctg
      541 ttaaacggtc tttggtcacg aagagctttt tacttcctcc gataaaggca atgcgtttgc
      601 agcctttttt gatgaaatat tcagtcgcat caaaaccagc ttgaacattg tcgttgtcga
      661 caagtgggat gaaaggagat agagatttac ctaggataag gaaggggaac tgttcttctg
      721 cgacgagttt tacgagaggg tcttcttctt gggcatagag aaagattagc ccatctacac
      781 gcttgccgta gaccatttgt gaaatagcgt tgagacgctc cttctcatct ttccctgttg
      841 ctatctgaat ggcatagtgg ttttcagatg cgacttgaga gatgccacgt agaaccgatg
      901 gaaagaaagg attctggtag aaggcgtctg agtcatcagg aagaactaat ccgataacct
      961 gagtatagct gcttaccaag ctacgagcgt tgaggtttgg gtggtagttg agttccttca
     1021 tagctttgcg aacgcgtttt tttgtttcgt cgctaatggt tgatttattt tgaataacac
     1081 gggttacggt tgaaggcgaa acaccagcag ccttggccac gtctttaatc gtaacgggca
     1141 taaaaatctc ctatttatgg taatttggat cacggaaatg tgttttataa aagatagtga
     1201 ccagatacag aacaaaaaga atattttgta cagtaatcag ggttgtcata ttttggccaa
     1261 ataatcccaa aataagtgta atcagagtcg gcaatcctaa acagttcaag ataaagtgat
     1321 agcactcttt aaaggttcta aatgaaaaga ggcgtgattt cttagtgata taaaggagaa
     1381 gactagctcc tagagagacg ataaagaaat tcaaaccaaa gaggaagctc gcaccgagaa
     1441 ctaggaagag gctgatatag acacgatttt gttggtacca gtctttagaa attgcttggg
     1501 tcaagctgtc tttgcttttg aaactctcag tctgaatggc tcggtaagag atgcgggtca
     1561 gttccttgct ttccttgctg atgactagct catttgtatc gaaatgcagt tgcaagtcct
     1621 taggtaattc cttgatttga cttggaccaa tcacaacaga aggggcttga ctagctgttc
     1681 cagtataagt taatgtgcca tcgacaattg tagcatgttc agagagatcc tggacaacct
     1741 tatctgtcag aggttcatag acattatcga taaaagtttc tagcggatag gtctcctggg
     1801 agctgttttg gatagcaatg ggtaccatag acaagctgat aaggaagata ctggtaaaga
     1861 gaagttgaaa ccagttgagc tcgaaacgtt tggacagggg cttacgaaac ccccaaatac
     1921 ttgaaaaata ggaaaatgga tatggaagca taggtatctt tctaaaaggt gttttctata
     1981 tgagtattat tatatagaga aatgcgcttt atttcaagtc taggagaaaa attgcttgct
     2041 acaaggatat tatttacagt gacaattgct aataatcaat gaaaatcaaa gtgcaaacta
     2101 gccacaggtt gctcaaagca caactttgag gttggagcta aagctgacgt ggtttgaaga
     2161 gattttcgaa gagtataaaa tgaaaaaggg tggcggggat aaattatccc ttgtcgccac
     2221 cacttgtaag tcctgaaaca aagttctttt gtaggaagaa gaagagaata cagattggaa
     2281 gggcgatgag gatagcacct gctgagaagt aggcaatctt caagtttttc gcattgttaa
     2341 cgaaggtttg gagacctacg gcaacagtaa agtattcttt ctcacgaagc aagaaactag
     2401 agaggatgta gtccccgaaa ggtcccatga aggcccagag agcttgtacg gcaaccattg
     2461 ggcgaacaag tggtagaaca atttgccaga agcggcggaa gtgtcctgca ccgtctagtt
     2521 ttgcagattc gtctaaagac attggcactg tatcgaagta gcctttcatg agccaagcat
     2581 tcatcgggat accaccacca acgtagagga agatgaggaa ccagttgtgg ttaagggcgt
     2641 tcaacataag cgccataacg aagaaggctg tcaaagcggc catagttggc accatttgga
     2701 tgatcaagaa gaagaccaaa ctttgtttac gagccaagaa gttgtaacgg ctgtaagcat
     2761 aaccagcaag tacgatgata cttgtttgaa cagccatggt aattaaggcg ataatcaaag
     2821 tgttgaggta ccaagtaccg tacaaggttt cagtgaagag gcctttaaag ttatcaaaat
     2881 tgaggtcgat attagtatct agtttaaagg ctgagacgtt acctgcttta aaggctgaca
     2941 taatggtaat caacagtgga tagataatta caattgatag accaatcagg taaaggtaag
     3001 taaggctttg agtcagtcta cgtttgagtt taattgagtt attcatctta gacgtcctcc
     3061 atatcaaatg cgtgtagttt cttgaatgcg atcatagaga ttgagatgac aatgatagag
     3121 ataatcaagg taacagctgc cgccattgag tattgaggag atgtacctgt tgtcaaacgg
     3181 tagatccatg agatcaagat atcggttgaa ccagctccac ctccgacact accaggtcct
     3241 ccaccattga agaggtacat gatagagaag ttgttaaagt tgaaggtgta ttggctaatc
     3301 aaagtaggtg ccgcaacagc caaaatcatt gggaaagtga tgttgcggaa tttttgccaa
     3361 gcgttggcac cgtcaatata agctgcttcg taaaggtcgt taggaataga ttgcaagata
     3421 cccaaagtca aaacgtagat gtatgggaat ccgagccaac cttgcatcat aatcaaggca
     3481 atcttagtcc aagttgggtc tgttttccaa ggaataagag ctccatcaag gaaaggaagg
     3541 aatttagcca agattggcaa tacttgagtg ttgatagcac cgacactatc gttaaacatg
     3601 tttgagaatg tcaagatagt gatgaaggct gggacagccc aaggaagaag gaaaataaca
     3661 ccaaagatac gttttccttt gataaatggt tggttggcaa tgatagctgt gaagatacca
     3721 attacgattt gtaaagtaga agctgccaaa gcccaaatga tagtccaaga aagaacagaa
     3781 ccaaaggcag aacggaaggt actcaagctc caaatgtttg taaagttggt caaaccaacc
     3841 cagtccaaca acttgtttgg tggcaagtgt tggaagtcgt agttggtaaa ggcgatcatc
     3901 aaggttacga taactgggaa gataatcgcg aaggtcatgg caacataaga tggaatgatc
     3961 aagaggtaag ggaagccatt ttcataaatc cctttgatca tgtctttgag tgtgcgtgga
     4021 actggaattc cattgttaat gcgttttgca atcgtatgtg catctttgat atttgagaaa
     4081 taaaagagta cataaacgat tacaaagatt agatggaagg caccacgaat cagcataaag
     4141 agggaattat cacgacctgg tttgtcacca agagtgatga ggttgctcaa ttcaggggtt
     4201 gcaagtgcta ggaagtaaag gacaaatacg atggttacac caaggaagat aaaacctttg
     4261 gctttttgtt tattgtaaat ctgtcctaac ccaggaatga tagacagcag ggctgcttta
     4321 ctaggttgtt gcttttccat attaactcct ttcataggat actacttttt tataagaaag
     4381 ctaaattatt tgtgtctcta ttgataaatt caaaggggga tttgatttcc accccccttg
     4441 aacaaatttt ttattcacca aatttttgtt tgattgtttc tttgatcaat gttacagcat
     4501 cgttagcagc tgttttagca tctttttgac cacttacagc atcaaagagc atatttttcg
     4561 ctggatccca aactgcagac atttgagaga tgtttggcag tggttgagtg ttcttgaact
     4621 gtttgataac agctgttgtc aactcatcgt ttttaccttc agcgtatgaa cgagcctcag
     4681 tattagctgg gatttcgtta gtcttatcat ataatacttt ttgttgttca gttgcaacaa
     4741 ggaagtctac aaatttttga gaagcttcaa ggttcttaac ggcttgagga atgacccaag
     4801 ctttaccacc accgaatgca gcatattctt ttccatttgg aagagttggg atagttgcaa
     4861 ctccgtagtt tactttagca tctttaaagg cttgagcttt ccaaggtccg tcgatgatag
     4921 cagctgtttt accttcttgg aattgagttt ggattaagtt tccagcacct tctgtatctt
     4981 gcataccttt aggccatttt tcgtaccaag atttagcgta gttgatacct acgatagaac
     5041 cgtcgtttgc aagaccgatg tctttagcgt ctttaccgtt ttggccaaag acgtaagcac
     5101 cgttaccggc aagaagtcca tatgtatagt agaagtttgt ccagtcagct aggaaggcag
     5161 tagttttacc atcttcacca gcgaatgcgt atttgctatc tttagcaagg ttttccaagt
     5221 cagcaaatgt ttttggagca tctttcacca agtctttgtt gtagtacata acaagtgact
     5281 cgataacggc aggagcaccg taaactttac cattagcagc tgttacaaga gatttagttg
     5341 tgtcgtctgt tttagcacca tcgctcaatt tcacttctga aagttgtccg tcagaaccaa
     5401 ggctacctac acggtcgtat ggagccatca taacatcagg gacattacca gattggttgt
     5461 caagagaaag tttatcaaga cctcctagag catcaccagt tttaagagtg acttttactc
     5521 cagcttcttt ttcataagct ttagcaacct cttcaatata gctcttatat ccctcgtcta
     5581 catatacagt gagttctttg acttcagatg aaccagaatc agcaggctta tcagcagttt
     5641 tgcttccgca agctactaag agcaagctag caagtgtagc agttccaagc accgcagcgc
     5701 tcttcataaa tttagatgac atagtgtatt cctcctaaag aatagcaagt tttattgata
     5761 aggaaacgca aacgttttcc tttatgagct tagtatagca caaatagaaa acggttgcaa
     5821 gtattttttg taaaaatttt aaaaaatttt taagcttgat ttgatagcat aattttgcat
     5881 tttaatagaa gaaaagtatg aaatagataa gaatacagta tttttaataa aaatatatgg
     5941 aatctgtcta aagagggaaa tcaggagggg ctacctccct gtttctaatc tatatctatt
     6001 ttctatagac gtttgtgctt tattgcatat aaattcaagc tccctaagga ggttttgtac
     6061 tttgtagact gtctcgtgag agtcaaactt taggattaga tagttttaag ttatctttgc
     6121 taaaatgagt tagtctcctt aaaaataatc aaaaaagttt tttaaaaacg cttgcaatta
     6181 tgcttgaaaa ggagtatact tataagtaac gcaaacgttt gcgtctgaaa aatacgcaac
     6241 gttccattat tttaacacac gaggtgctat tatgaaaaaa cgtcaaagtg gtgtgttgat
     6301 gcacatctct tctcttccag gagcttacgg aatcggatca tttggtcaaa gtgcttacga
     6361 cttcgttgat ttcttggtcc gtacaaaaca acgttactgg caaatccttc cattaggagc
     6421 aactagttac ggggattctc cttaccaatc tttctcagcc ttcgcaggaa acactcattt
     6481 tatcgattta gatatcttgg tggagcaagg tttgttggaa gcaagtgacc ttgaaggagt
     6541 tgactttggt agcgatgcgt ctgaagttga ctatgctaaa atctactatg cacgtcgtcc
     6601 tcttttagaa aaagcggtga aacgtttctt tgaagtcgga gatgttaaag attttgagaa
     6661 atttgctcaa gacaaccaat catggcttga gctctttgct gagtatatgg ctatcaaaga
     6721 gtattttgac aatcttgctt ggactgaatg gccagatgca gatgctcgtg ctcgtaaagc
     6781 ttcagcactt gaaagctatc gtgagcaatt ggcagacaag ttggtttacc accgtgtgac
     6841 tcaatacttc ttcttccaac aatggttgaa attgaaagct tacgctaacg acaaccacat
     6901 cgaaatcgtt ggggacatgc caatctacgt agcggaagat tcaagtgata tgtgggcaaa
     6961 tccacatctc ttcaaaacag atgtcaatgg taaggctact tgtatcgcag gatgcccacc
     7021 agatgagttt tctgtaactg gtcagctttg gggtaaccca atctatgact gggaagcaat
     7081 ggacaaagac ggttacaaat ggtggattga acgcttgcgt gaaagcttca aaatctacga
     7141 tatcgttcgt atcgaccact tccgtggctt cgaatcttac tgggaaatcc ctgctggttc
     7201 cgatacagca gcacctggtg agtgggtgaa aggtccaggc tacaagcttt ttgcagccgt
     7261 taaggaagaa cttggtgagc taaacatcat cgcagaagac cttggcttca tgacagatga
     7321 agtgatcgaa ttgcgtgaac gtactggctt cccaggaatg aagattcttc aatttgcctt
     7381 caacccagaa gacgaaagca ttgatagccc acacttggca cctgctaact cagttatgta
     7441 cacaggaaca cacgataaca atacggttct tggttggtac cgtaatgaga ttgatgatgc
     7501 gactcgtgag tacatggctc gttacacgaa ccgtaaagaa tacgaaacag tggtacacgc
     7561 tatgcttcgt acagtatttt catcagttag ctttatggca attgcaacta tgcaagattt
     7621 actagaattg gatgaggcag ctcgtatgaa cttcccatct acccttggtg gaaactggtc
     7681 ttggcgtatg actgaagatc aattgacacc agctgtcgag gaaggtttgc ttgacttgac
     7741 aacaatttat cgccgaatta atgaaaattt ggtagattta aagaaataag acaataatca
     7801 ggagacaact aaacatgtta tcactacaag aatttgtaca aaatcgttac aataaaacca
     7861 ttgcagaatg tagcaatgaa gagctttacc ttgctcttct taactacagc aagcttgcaa
     7921 gcagccaaaa accagtcaac actggtaaga aaaaagttta ctacatctca gctgagttct
     7981 tgattggtaa actcttgtca aacaacttga ttaaccttgg tctttacgac gatgttaaaa
     8041 aagaacttgc agctgcaggt aaagacttga tcgaagttga agaagttgaa ttggaaccat
     8101 ctcttggtaa tggtggtttg ggacgtttgg ctgcctgctt tatcgactca attgctactc
     8161 ttggtttgaa tggtgacggt gttggtctta actaccactt tggtcttttc caacaagttc
     8221 ttaaaaacaa ccaacaagaa acaattccaa atgcatggtt gacagagcaa aactggttgg
     8281 ttcgctcaag ccgtagctac caagtaccat ttgcagactt tactttgaca tcaactcttt
     8341 acgatattga tgttactggt tatgaaacag cgactaaaaa ccgcttgcgt ttgtttgact
     8401 tggattcagt tgattcttct attattaaag atggtatcaa ctttgacaag acagatatcg
     8461 ctcgcaactt gactctcttc ctttacccag atgatagtga ccgtcaaggt gaattgctcc
     8521 gtatcttcca acaatacttc atggtttcaa acggtgcgca attgatcatc gacgaagcaa
     8581 tcgaaaaagg aagcaacttg catgaccttg ctgactacgc agttgtccaa atcaacgata
     8641 ctcacccatc aatggtgatt cctgaattga ttcgtctttt aactgcacgt ggtatcgagc
     8701 ttgacgaagc aatctcaatt gttcgtagca tgactgccta cactaaccac acaatccttg
     8761 ctgaagcgct tgaaaaatgg cctcttgaat tcttgcaaga agtggttcct cacttggtac
     8821 caatcatcga agaattggac cgtcgtgtga aggcagagta caaagatcca gctgttcaaa
     8881 tcatcgatga gagcggacgt gttcacatgg ctcacatgga tatccactac ggatacagtg
     8941 ttaacggggt tgcagcactc catactgaaa tcttgaaaaa ttctgagttg aaagccttct
     9001 acgaccttta cccagaaaag ttcaacaaca aaacaaacgg tatcactttc cgtcgttggc
     9061 ttatgcatgc taacccaaga ttgtctcact acttagatga gattcttgga gatggttggc
     9121 accatgaagc agatgagctt gaaaaacttt tgtcttatga agacaaagca gctgtcaaag
     9181 aaaaattgga aagcatcaag gctcacaaca aacgtaaatt ggctcgtcac ttgaaagaac
     9241 accaaggtgt ggaaatcaat tcaaattcta tctttgatat ccaaatcaaa cgtcttcatg
     9301 agtacaaacg ccaacaaatg aacgctttgt acgtgatcca caaatacctt gacatcaaag
     9361 ctggtaacat ccctgctcgt ccaatcacaa tcttctttgg tggtaaagca gctccagcct
     9421 acacaatcgc tcaagacatt atccatttaa tcctttgcat gtcagaagtt attgctaacg
     9481 atccagcagt agctccacac ttgcaagtag ttatggttga aaactacaac gttactgcag
     9541 caagtttcct tatcccagca tgtgatatct cagaacaaat ctcacttgct tctaaagaag
     9601 cttcaggtac tggtaacatg aaattcatgt tgaacggagc tttgacactt ggtactatgg
     9661 acggtgctaa cgtggaaatc gctgagttgg ttggagaaga aaacatctac atcttcggtg
     9721 aagattcaga aactgttatc gacctttacg caaaagcagc ttacaaatca agcgaattct
     9781 acgctcgtga agctatcaaa ccattggttg acttcatcgt tagtgatgca gttcttgcag
     9841 ctggaaacaa agagcgcttg gaacgtcttt acaatgaatt gatcaacaaa gactggttca
     9901 tgactcttct tgatttggaa gactacatca aagtcaaaga gcaaatgctt gctgactacg
     9961 aagaccgtga cgcatggttg gataaagtca tcgttaacat ttctaaagca ggattcttct
    10021 catctgaccg tacaatcgct cagtataacg aagacatctg gcacttgaac taatactctt
    10081 cgaaaatctc ttcaaaccac gtcagcttta tctgcaacct caaagcggtg ctttgagcaa
    10141 cctgcggcta gcttcctagt ttgctctttg attttcattg agtataagat acaaatttat
    10201 actaatacat cttgtaaaaa agcgagtttc gattgaaatt cgctttttta aatgctgtgg
    10261 atttgggtca atcttgtcta aaaataggga aatcctagat acagtgaagg ctttaaatgc
    10321 tggtttttac tgtcttcagc cttatatttt ttcgtagttg gttacctcat atctcttgta
    10381 ttcgcttaca taaagtatta taatataatt gtaggaaaga aggtgttttt atgatataca
    10441 cacttaaatt ggtgttgttt attacctttc ttgtaataag cttgttacct gataagattt
    10501 ttggaaaaaa taaaaaaatt tggaaaatag tttttgcaat attgacggca gtggcagcat
    10561 tgtcatttat gtactaagtt attttaagaa tgtagggaaa taaaccctac attcttttta
    10621 gttttttctg ttttctaaat tctatttatc caagcgcttc aacatttctt gcttcttcgc
    10681 ttcaagttct gcacgctttt cttcgatttc ggcatgtttt ttctcgagtt cagaacaact
    10741 tgcatcattg ctaaattctt ttcgccatca ggagataggg tgagtcgaca tgtctattac
    10801 tcacccaaag cagtcctaca aagcaggaat tttctgttac ttttttggaa atagtaacgt
    10861 ttatacagct ttgacacttc gtatcaaagc gccaaacaca ctccgaggga tttacagaaa
    10921 gcagaaaagg aatgatctgg tataagatca ttccttttct ctctttttct ttaagtaatt
    10981 atatacaatg tacgacgaag tcgtcattgc aatgctgatc caccacctaa agggaacttt
    11041 aaacaacatt gataagataa agaatataaa caacgaaaat acgttatacc caattaattt
    11101 tattgtatat ctcatgatta aaagttaatc cttccgttgt taggaatggc atcattttta
    11161 tcccataatt gtgctaaata agtccccggt gataataaat tcatagcgaa ttctaaagca
    11221 acatcattta caaaccaact acctagatat ctagaaattg ctgaacgaat agcacttttt
    11281 gctgcatgtt ttccttttac tttaattaga tttgcaaggc ctgcagtagt tcctcctaag
    11341 gctaaagcta ttgcagtatc taatagagca cccatttgat taactgtaat accttgccaa
    11401 gctgctctaa atggagagta tgtaggtggg attgtataat cgccttgtaa ttgtcggtta
    11461 attacttctt tgatccattg ttgtgagacg tctggatgaa aagattggat ttcgtttgca
    11521 agtgtattga tttgttcttc tgttagagaa gtgacaggtt gaagttccat atttgtttca
    11581 atttgcgata cttgttcaga agcgtataca gctgaaacac ttggaatcgc tgatacaatt
    11641 aacacaattg acgtcaaaaa accgaaataa atttcattaa tttgttcatg agcttttctc
    11701 ctttttattt gtatctgctt acattttatt atatactgtt attatagtca agaaaaatat
    11761 gctattatgt taaaaaaata tttttcaaaa tataaatgga cggatttatt ttggatttta
    11821 tttgttattt tgacctgcct ctatattggt aaccatgatt tgtttactct caatcatcaa
    11881 gaattctctt ttcgtggtag cttttggggt ttggtactga ccttatatca cttattgttc
    11941 attgataagt ttgtaatttc gaatcgaaaa taaagattag agctatgctt gactgtgtac
    12001 ttttaggatt gattttggag gaagattttg tctctattat ttattatttt aaatttattt
    12061 attttgtata agatctattc tttgaggcgg gaaaaatcga aatacttgat ttatacggcc
    12121 tatatcatat ttggggtaaa tgtagtatat ggtattcaat ggttattaaa agaactgatt
    12181 tcaactattt ccccttaatg cgtatggaaa ctataacaaa acgcataaga ttaaggtttg
    12241 tgtacctgtt cttatacgtt tttgtcatat tgaagatttt cggtaagttt tctacttttg
    12301 cgaagtctag tttatactca atgaaaatca aagagtaaac tagccgtagg ttgctcaaag
    12361 tacagctttg aggttgcaga taaaactgac gaagtcagct caaaacatgg ttttgaggtt
    12421 gtagatgaaa ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac
    12481 gaagtcagct caaaacatgg ttttgaggtt gtagatgaaa ctgacgaagt cagtaaccat
    12541 acgtacggca aggcgacgtt gacgtggttt gaagagtatt agaatgcttt cccaaccaga
    12601 atctctgctt cgatggtaat ctctgtcagt tggctccagt caatcttgct ctggtcaacg
    12661 tgaaagagga gaggagtcat actgagtagg gcttggagtt gttctgctgt gatagtctta
    12721 gtcagagagg cagtttgact agataggatg gtaaagtgtt cctggaaatg ctccttgata
    12781 tcttggttag aatactcctt gtttgtcagc tggtcctgta ctctttgacg gatttctttg
    12841 aggtgatttt cagttgggat aacctttatc aagataccgt ctttggataa aacgcgacga
    12901 aattctccat agttggcagg tgagaagata tcaagcagaa tatccatgtt agcgtctttt
    12961 ataggaaggc gtgccaagtc gccaacgaac caattgactg cccagttggg ttcactttta
    13021 gcagcgattt ggactgaatc tttggagatg tcaaaggcat agaaagtttt ttcagagtga
    13081 ctttcttgta gtttgcgaga atagaatcct tcaccacaac cgatatccaa aattgttgtg
    13141 gtagtttttg agcttgcaag caagtcagat acagcatcta agatagcttg gtaaaagccg
    13201 gcttctagga tttgttgacg gttttgaaaa ttttccttgt catagttagc agattgcttg
    13261 atttgaggtg ctagattgac atagccaaat ttcgccaagt caaaagaatg acggttgcag
    13321 cacttgaaat tagtctctaa cagagtcaga ttttcttgac agataggaca ggcaaaggca
    13381 gtcgcagaag caaaacgctg aagtttgggc ttgagatttg tattcatagt ttaagtgtat
    13441 caaaagaggc aaatgaaagc aactttagga ataagtagat gggagattca gtagaaataa
    13501 aactaattct ccaatttata gaatgaaatt gcttttatat ctaaattgct atataataat
    13561 gataaggagg aaataagtat gttaaaagaa gtattaaccg ttgcaaaagt tgcgaaaaaa
    13621 tcttcattat ttttgggtgg tgtcgcattt ggtacccttg gtttgaaaat cttagcaagt
    13681 aaggaagcta aaaaaggtta ttctaaagct ttggctaagg cttacaagtt gaaagacgag
    13741 ctagatgcat ctgtttctgt tgtgaagcaa catggagacg atgtcttgca agatgccaaa
    13801 tatttgtacg agcaagagaa aaaagaagag caattagata gccttatagg tgaataatat
    13861 gtcttttaaa gtgctacata gaggatacca acatatccga ctatcatctt ctttttcact
    13921 taccttggat attcaagact atcttcgttc cttggcgaga gatgaaaagg ggattgagtc
    13981 tatccagttt tacatggatc aacagcactt tactctacgc ataaaagaag gcttttctgt
    14041 attagataat gcagaagcct ttttaaaaag aattgataaa gggaaagttt ctgagttgat
    14101 gactcttccc attcgtagag aagagagtgc ttattctatt gtttcaggtg cagcggttaa
    14161 gcgtgtactt tttcgtagtt ttgtgccgta tcctattcgc tatatatgga cttgttatca
    14221 ggctttgggt tatattagag aagcctatca aacactagcg cgtaaggaac taacgatgga
    14281 agtcttggac tgttcggcta ttttattgtc cttgtttatg aaccaatcca agacagctag
    14341 caatatcatg tttatgcttg atttggggaa tcatttagat cagtggtcct tgaaaaaaac
    14401 tgcaacagat ttagaacaga gtcttcttgc aaaagagagc gatgtattcc tagtacaggg
    14461 cgatacggtt gttagtataa agagttccga tgttcaaata ggagatgtct tgatcttatc
    14521 tcaaggaaat gaaattctgt ttgatgggca agtagtttca ggtttaggta tggtcaacga
    14581 aagttccttg acaggagaga gttttccagt tgaaaaaaga gagtctgatt tggtttgtgc
    14641 aaatacagta ttagaaactg gagagttacg cattcgtgta acagataatc agatgaacag
    14701 ccgtatttta cagctgattg agttgatgaa gaaatctgaa gaaaacaaga aaacgaaaca
    14761 acgctatttc atcaagatgg cggataaagt cgtcaaatat aatttcttgg gggctgggct
    14821 gacttaccta ttgacaggtt ctttttctaa ggctatttct ttcctattgg tcgatttctc
    14881 ctgcgctttg aaaatctcta ctcctgtagc ttatttgaca gttatcaagg aagggttgaa
    14941 ccgtgaaatg gtgattaagg atggagatgt tctggagaaa tatctggaag ttgatacttt
    15001 cttgtttgat aagacaggaa caatcacaac tagttatcct atagttgaaa aggtgttacc
    15061 ttttggagac tatagtgagg aagatattct cagaatcagt gcctgtcttg aggaacacat
    15121 ttatcatcct attgctaatg ccatcgtcaa gcaagctgag atagagggaa ttgaacatga
    15181 ggaaatgcat gggaaactcc aatatatcgc aagcaagggg atcaaatctc atatagatgg
    15241 ccaaccagtt cttattggga attatgtctt gatgcaggat gagcagattc atatcagttc
    15301 agaacaaaat gctttaattg aagagtacaa gagtcactac aatctcttat tcttggctta
    15361 tcaaaatgaa ttgattggaa tgttctgcat tcatactcct ttgagaaaag aagcaaaaac
    15421 agccttggat aaacttaagg cacaggggaa aaaattgatt ctggcaacag gagacacctt
    15481 gattaggaca gaggaattag tcaaagattt gccctttgat caggtctata cagacttgaa
    15541 acctgatggg aaatttgagt tagtagagaa actgcagaaa gcaggtcaca ctattttgat
    15601 ggttggagat ggattgaatg actcagcggc tttaactcta tcagatatcg gtgtggtgat
    15661 gaatgagagt gcagatattt ctaagcagat gagtgatatc ttattgttag ataatcgttt
    15721 ggatttcttc caagagttgg attcgttatc atcatctttg caaacactca tcaagaaaaa
    15781 tattcaagat accgttgtcg taaatagtag tttgattggc ttcggcttat ttaattggct
    15841 cagtccttca aatctctcta tcttacataa tctaacaacc ttgcgcattg tcctgcgtag
    15901 cctgtctatt aaaaatagat agatgagagt tattaacagc aaaaaggagt tacctttctc
    15961 gaggttaact cctttgttta tagataaatg ttgaatagtt tagtaagtca atacaaagta
    16021 ttttttcttc ccacgacgga taacagtcag ttcattttct aacttatcag cgtcactcaa
    16081 gacatagtca aggtcttgga tgcggtcgcc gtttacgtag atggctccgt tttggacgtc
    16141 ttcacgggct tggcgttttg agttaactat accagatgag acgagcagtt ccacgatatt
    16201 gttgttttcg tctgcctgta cttggtagtt tggcacacca cgaagtcctt gtttgagctc
    16261 tttgacagaa aggtttttga tgtttcctgc aaagagttgc tcagtgatgt taagtgcttc
    16321 tttgtaggct tcttctccgt gaacaagtgt aacaacttca cgagccaaga ctttttgagc
    16381 caagcgttcg tgtggcgctg cttcaaattg tttacgaata tcttcaatct catcaagtga
    16441 caagaaagta aagattttca agaagcgaac agcgtcagcg tccatcacgt tcatccagaa
    16501 ttggtacatt tcgtatggag aagtcttttc gggattgagc cagacggcat ttccttctga
    16561 tttaccaaat tttttaccag ttgcatctgt gattagtgga acagtgataa cgtgaccagt
    16621 cttgtccgcc ttacgacgaa gcaattcggt accagctgtc atatttcccc actggtcaga
    16681 accaccgatt tgaagagtga cattatggtc ttggttaagg acgaagaagt cgtacccttg
    16741 catgatttgg taagcgaact cagtgtaaga aattcctgtt tcgatccgtt ttttaacaga
    16801 ttccttactc atcatgtagt tgaccgtgaa gtattttcca atatcacgga ggaagtcaat
    16861 gaagctgatg ctgccaaacc agtcgtagtt gttgaccatg acagccttgt tttcgccatt
    16921 ttcaaagtca agaaaacgag aaagttgtcc ttggatagac ttgacccagc catctactgt
    16981 gtcttttgtt tggagactac gttcagcatc tttgaaggac ggatctccga tgagacctgt
    17041 agcaccgcca acgagcgcat aaggtttgtg acctgctagt tgcaagcgac gacttgtcaa
    17101 gattgcgaca aggtggccta ggtgaaggct gtcagcagtt ggatcgtagc cagtataata
    17161 agaaacttga ccttcttcta gggctttacg caaagcttct tcatcagtcg tttgaaatat
    17221 caaaccacgc tcttttagct catcaaaaat gtgcatgtgt cttttctcct ttttaaaatt
    17281 attgtttcta cctattgtat cacaaacttg ggcaatagcc tagcagaata gggaagaaag
    17341 tggctatttt attgaaaatt tcccttttgt ggtataatag ataaagtgag gaaatccatg
    17401 caaaatcaat taaatgaatt aaaacgaaaa atgctggaat ttttccagca aaaacaaaaa
    17461 aataaaaaat cagctagacc tggcaagaaa ggttcaagta ccaaaaaatc taaaacctta
    17521 gataagtcag ccattttccc agctatttta ctgagtataa aagccttatt taacttactc
    17581 tttgtactcg gttttctagg aggaatgttg ggagctggga ttgctttggg gtacggagtg
    17641 gccttatttg acaaggttcg ggtgcctcag acagaagaat tggtgaatca ggtcaaggac
    17701 atctcttcta tttcagagat tacctattcg gacgggacgg tgattgcttc catagagagt
    17761 gatttgttgc gcacttctat ctcatctgag caaatttcgg aaaatctgaa gaaggctatc
    17821 attgcgacag aagatgaaca ctttaaagaa cataagggtg tagtacccaa ggcggtgatt
    17881 cgtgcgacct tggggaaatt tgtaggtttg ggttcctcta gtgggggttc aaccttgacc
    17941 cagcaactaa ttaaacagca ggtggttggg gatgcgccga ccttggctcg taaggcggca
    18001 gagattgtgg atgctcttgc cttggaacgc gccatgacta aagatgagat tttaacgacc
    18061 tatctcaatg tggctccctt tggccgaaat aataagggac agaatattgc aggggctcgg
    18121 caagcagctg agggaatttt cggtgtagat gccagtcagt tgactgttcc tcaagcagca
    18181 tttttagcag gacttccaca gagtcctatt acttactctc cttatgaaaa tactggggag
    18241 ttgaagagtg atgaagacct agaaattggc ttaagacggg ctaaggcagt tctttacagt
    18301 atgtatcgta caggtgcatt aagcaaagac gagtattctc agtacaagga ttatgacctt
    18361 aaacaggact ttttaccatc gggcacggtc acaggaattt cacgagacta tttatacttt
    18421 acaactttgg cagaagctca agaacgtatg tatgactatc tagctcagag agacaatgtc
    18481 tccgctaagg agttgaaaaa tgaggcaact cagaagtttt atcgagattt ggcagccaag
    18541 gaaattgaaa atggtggtta taagattact actaccatag atcagaaaat tcattctgcc
    18601 atgcaaagtg cggttgctga ttatggctat cttttagacg atggaacagg tcgtgtagaa
    18661 gtagggaatg tcttgatgga caaccaaaca ggtgctattc taggctttgt aggtggtcgt
    18721 aattatcaag aaaatcaaaa taatcatgcc tttgatacca aacgttcgcc agcttctact
    18781 accaagccct tgctggccta cggtattgct attgaccagg gcttgatggg aagtgaaacg
    18841 attctatcta actatccaac aaactttgct aatggcaatc cgattatgta tgctaatagc
    18901 aagggaacag gaatgatgac cttgggagaa gctctgaact attcatggaa tatccctgct
    18961 tactggacct atcgtatgct ccgtgaaaag ggtgttgatg tcaagggtta tatggaaaag
    19021 atgggttacg agattcctga gtacggtatt gagagcttgc caatgggtgg tggtattgaa
    19081 gtcacagttg cccagcatac caatggctat cagaccttag ctaataatgg agtttatcat
    19141 cagaagcatg tgatttcaaa gattgaagca gcagatggta gagtggtgta tgagtatcag
    19201 gataaaccag ttcaagtcta ttcaaaagct actgcgacga ttatgcaggg attgctacga
    19261 gaagttctat cctctcgtgt gacaacaacc ttcaagtcta acctgacttc tttaaatcct
    19321 actctggcta atgcagattg gattgggaag actggtacaa ccaaccaaga cgaaaatatg
    19381 tggctcatgc tttcgacacc tagattaacc ctaggtggct ggattgggca tgatgataat
    19441 cattcattgt cacgtagagc aggttattct aataactcta attacatggc tcatctagta
    19501 aatgcgattc agcaagcttc cccaagcatt tgggggaacg agcactttgc tttagatcct
    19561 agtgtagtga aatcggaagt cttgaaatca acaggtcaaa aaccagggaa ggtttctgtt
    19621 gaaggaaaag aagtagaggt cacaggttcg actgttacca gctattgggc taataagtca
    19681 ggagcgccag cgacaagtta tcgctttgct attggtggaa gtgatgcgga ttatcagaat
    19741 gcttggtcta gtattgtggg gagtctacca actccatcca gctccagcag ttcaagtagt
    19801 agttctagcg atagcagtaa ctcaagtact acacgacctt cttcaagggc gagacgataa
    19861 ttctctaaat gaagtggcca atcaatggat tgccactttt ttcctttcgt gttacaataa
    19921 gggtatgaat cagtatcaga aaaagattgt taacggaaaa atttattcgc tcctatccgg
    19981 cttaatatgg ggaatctgtg gaattttagg agagtacttc tttactcatt atcaggtgtc
    20041 ttcgggctgg attacctcta tgcgtttgac actggcaggg agtcttgtac tcatttggtc
    20101 tgcaatacaa ttaaaatcgc aagtgctaga tatttggcga gacaagaaaa attacctgcc
    20161 ctttttagcc tatgctattt tggggatttt ttcagttcag tattttttct atctctgtgt
    20221 agaatactca aatgctacga cagcaactat tttacagttt attagccctg tctttatcct
    20281 cttttataat cgcttggttt atcaaaaacg agcgtcaaaa agcgctgttt tctatgtttt
    20341 ggttgccatg ctgggtgttt gcttgatggc gacaaaggga gatctctctc agttatccat
    20401 gacgccgcta gctcttataa caggtttgct gagtgccatg ggtgttatgt ttaatgttat
    20461 cttgccccaa ccttttgcta agcgttatgg ttttgttcct acggttgggt gggggatgat
    20521 tttggcaggt ttgtttagca atgtcctctc gccggtttat cagctttcct ttactcttga
    20581 tatttggagt atcttgattt gcctcattat cgctttcttt ggaacggctt ttgctttttt
    20641 catttccatg aaggctgtgt ccttggtttc tcctttggtg gtttccgtta tcagtgccag
    20701 tgaacctctc tcttctgctc tcttgagtgt tttgttctta ggattagtag tggattggtc
    20761 cctccttcta gctatagcct tgattatttt acccatgata tttttgtcta tagaagaagc
    20821 gaaagaaagt agataaaaag tcttttctta attctaaaag tgtgctatac tagaatagtc
    20881 aataaaacac ggggagatag ttgtgaagag tgtttttagg ttgtatcggt aggggcttgc
    20941 ttttaccgac agcacgtttt atctcacaac cctaaaaaat catacctaaa aacagacaaa
    21001 aaggtttcaa atttgaggcc ttttttggta gaataggtat cattataacg aaccaggagg
    21061 cacctatgac tgctacaaaa atgaacgctc aagaaattat ccaatttatc gccaatgctg
    21121 aaaagaaaac cagtgtcaaa gtaacctttg aggggcaact cgcaactgct gtgcctagct
    21181 ctgttgtcaa actaggaaat gtcctattcg gagactggaa ggacgtggct ccgcttcttg
    21241 aaggtttggt agaaaatcaa gattatgttg tcgagcacga tgctcgtaat tctgcagttc
    21301 ctttgctaga taagcgtgct atcaacgctc gtatcgagcc aggtgctatt atccgtgacc
    21361 aggtggaaat tggtgacaat gctgttatca tgatgggagc tgttatcaat atcggtgctg
    21421 aaatcggtgc tggaaccatg attgacatgg gtgccatcct tggtggccgt gctatcgttg
    21481 gaaaaaatag ccacgttggt gcaggtgcag ttttggcagg tgtgattgag ccagctagtg
    21541 ctgaaccagt ccgtgtcgga gacaatgttc ttatcggtgc taatgcagtg gttatcgaag
    21601 gagtccaaat cggtagtggt tcagttgtcg cagcaggagc tattgttacc caagatgtcc
    21661 cagaaaacgt ggtagtagca ggtgttccag ctcgtattat caaagaaatt gatgcccaaa
    21721 ctcaacaaaa aacagcgcta gaggatgcgc ttcgtacctt gtaattgtaa aagtaaaaaa
    21781 gaggcggaac cctttttcca gcctctttct gctatatcgg aggacagata gatgttagat
    21841 ttgattcaga ctagacgaga tttacaccag ataccagaga ttggcttgga ggagttcaag
    21901 actcaggctt atttgctgga tgtgattgag aaattgacta cgggcaagga ttttgttcaa
    21961 attcgtactt ggcggacagg gattttggtc tacctgcagg gaagtcagcc ggagcgaacc
    22021 attggttggc ggacagatat tgatggcctg cctatcgtcg aacaaacagg tctacctttt
    22081 gcttctcaac accaaggtcg catgcatgcc tgtggtcatg attttcatat gaccattgcc
    22141 ttaggctgtc ttgagcgcgc ccttgaggag caacccaaga ataatctgct ctttctattt
    22201 cagcctgctg aagaaaatga agctggtggt atgctcatgt atgaggacgg tgcttttgga
    22261 gattggttgc caaaccaatt ctatggtctc catgttcgtc cagatttgaa agtcggccag
    22321 attgcgacta atactcatac actctttgca ggaacttgcg aggtgaagat ccgtttcaaa
    22381 ggcaaaggtg gccacgcagc ttttcctcat gaagccaatg acgccttggt ggctgctagt
    22441 tactttgtga cccaagtgca gtcagttgtt agccgcaatg tcaacccaat cgagggagca
    22501 gtggtgacct tcggcgtttt tcaagctgga accaccaaca atgtcatcac agacacagct
    22561 tttttacatg gaactattcg tgccttgaca caggacatga gtctcttggt gcaaaagagg
    22621 gtaaaaacag ttgcagaagg ggttgcagct gcctttgata tggaagtcga agtggaactc
    22681 aaacaaggtg gatacctacc tgttgagaac aatccagcct tggcgcgtga actgatggac
    22741 ttctttgacg aaaaagacgg aatcgagttg attgatatcg aacctgctat gacaggcgag
    22801 gactttggtt atctcctttc aaaggttgat ggcgtgatgt tttggctagg tatcgatagt
    22861 ccctacgctc ttcatcaccc tcaaatgagt cctaaggaag aagtcttagc tattggggtg
    22921 gctgcggtgt ctagtttcct gaaaaagaag gcagcagaat agagggcttg tatatgaaat
    22981 cggaattacg caagcaagtc ttgcatgaaa tgaaggcttt atctcaagaa caaaaacagg
    23041 ctatagacca agctttaacc gagcgaattt tacaacaccc cttttatcaa gaagccaagg
    23101 tcatcgcaac ctacctctct ttttctcatg agtttcaaac gcgggaactg attgagcagg
    23161 cgctgaagga cggcaagaag gttttaatac ccaaaactta tcccaagggg cgcatggact
    23221 ttgtagtcta tgatccgcag cagttggtaa aaactgcctt tgccttactg gagccacagg
    23281 gagatttgga agtggtggat gtatctcaga ttgatttgat tcatgttcct ggcctggctt
    23341 ttacgacgga tggatatcgg attggatatg gtggaggtta ttatgaccgc tatctggaac
    23401 atttttctgg tcgtactttg agtacggttc atccttgtca aattcaggac tttatacctg
    23461 aaaaccatga tattcctgtt caggaggtat taattgatga aggaaatctt tgatagacgt
    23521 taccctgtga cgagtttctt cctcttagtg acggccttgg tatttttact aatgttggtc
    23581 actgcaggcg gaaactttga cagggcagat acattatttc gatttggagc catgtatggg
    23641 ccagctattc gcctctttcc cgagcaggtt tggcgtctct tgtctgccat ttttgttcat
    23701 attgggtggg aacatttcat tgttaatatg ctttcacttt attatcttgg aaggcaggta
    23761 gaggagattt tcggctctaa gcagttcttt tttctctatc tcttatcagg aatgatgggc
    23821 aatctctttg tttttgtatt tagtcctaaa tccttagcag caggcgcctc tacctctctt
    23881 tatgggctat ttgccgcgat tattgttctt cgctatgcaa ctcgcaatcc ttatatccaa
    23941 cagctagggc aatcctatct gacacttttt gtggttaaca ttattggaag tgttctgatt
    24001 ccaggaatca gcctagcagg ccatatcggt ggtgcagttg gtggcgcatt tctagcagtt
    24061 atctttccag ttagaggaga aaaacggatg tataacacca gccagagatt aggagcggta
    24121 gtcttgttcg taggactcgc cattttgctt ttctacaagg gaatgggaat gtgacgacta
    24181 atactcaatg aaaatcaaag agcaaactag gaagctagcc gcaggttgct caaagcactg
    24241 ctttgaggtt gtagatagaa ctgacgaagt cagctcaaaa catggttttg aggttgtaga
    24301 tgaaactgac gaagtcagta accatatata cggtaaggcg acgctgacgt ggtttgaatt
    24361 tgattttcga agagtataat atgtaaactt gaataagaaa aaagctactt aaaaaatgag
    24421 tagcttttaa tgtgttttgg aaccattcga aacaacacag ctctaaaata gttattagcg
    24481 ttgtggaggt tctgcaatgc ctcccccagt gtttccaaga taattccaat tttcgtcaaa
    24541 cacatctcca ttgctctcat tgtcgtaagt ataacttaca tgtccatcag caccaatatt
    24601 cttatatttt ttatagtagc cattatttac tccgctgttg gaattgctag atgaatattg
    24661 ttctgatgat ccaccatttg ttgaactatc tccagaacca gaataacttt gacttccata
    24721 attattcgaa tatccattag tttgttcaga tgaactataa tctacatttg aattggaaga
    24781 tccattataa gactcattag aagcaccact agaagaatta ctttgactag aagattcctt
    24841 tgctttttca gcagcttttt cttcttcttt cttcaaaagt tcgatttgtt tttgatattt
    24901 atcaacaaga tcatttagag atttaagagt ttcttccaaa ttctcttgtt taaaagtttc
    24961 atcaactttt ttgataaaat caatttgttt tgtaatttct ttcacatttg tttcaagagt
    25021 tgctttatct ttaaacttct catcagaatc tttaacatca taagccaaac ctttttgcaa
    25081 atgaaaatct acaattgctt tagatgattc tttgactttg ttattaagat agtctttacc
    25141 tgcatcggtt ttaagtgaag tttcagatag ttcttttaat ttagaaatag attcatctga
    25201 agatgcatca aatgattcaa atagtttatc aacttgttct ttgtctgatt tgctatcttt
    25261 ttctaattgt acaatttttg cttgttgttc tgcttgttgt tggttatatg aataccatcc
    25321 aaaccctaat accaatacaa caccaactgc aactgatgaa atgattactt ttttattgtt
    25381 ttcgataaat tctacaaatt tgttctccat aatcttttac tttgatagtg tccgcaatta
    25441 cttt
//
LOCUS       DAVLDI010000030        25364 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLDI010000030 DAVLDI010000000
VERSION     DAVLDI010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.030"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            3..75
                     /locus_tag="VXD01_001257"
     tRNA            3..75
                     /locus_tag="VXD01_001257"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36..38,aa:Val,seq:tac)
     gene            81..151
                     /locus_tag="VXD01_001258"
     tRNA            81..151
                     /locus_tag="VXD01_001258"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:113..115,aa:Gly,seq:tcc)
     gene            186..259
                     /locus_tag="VXD01_001259"
     tRNA            186..259
                     /locus_tag="VXD01_001259"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:Ile,seq:gat)
     gene            342..431
                     /locus_tag="VXD01_001260"
     tRNA            342..431
                     /locus_tag="VXD01_001260"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:378..380,aa:Ser,seq:tga)
     gene            442..515
                     /locus_tag="VXD01_001261"
     tRNA            442..515
                     /locus_tag="VXD01_001261"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Met,seq:cat)
     gene            519..591
                     /locus_tag="VXD01_001262"
     tRNA            519..591
                     /locus_tag="VXD01_001262"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:552..554,aa:Phe,seq:gaa)
     gene            604..684
                     /locus_tag="VXD01_001263"
     tRNA            604..684
                     /locus_tag="VXD01_001263"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:638..640,aa:Tyr,seq:gta)
     gene            689..759
                     /locus_tag="VXD01_001264"
     tRNA            689..759
                     /locus_tag="VXD01_001264"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:721..723,aa:Trp,seq:cca)
     gene            774..846
                     /locus_tag="VXD01_001265"
     tRNA            774..846
                     /locus_tag="VXD01_001265"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:807..809,aa:His,seq:gtg)
     gene            857..928
                     /locus_tag="VXD01_001266"
     tRNA            857..928
                     /locus_tag="VXD01_001266"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:889..891,aa:Gln,seq:ttg)
     gene            938..1021
                     /locus_tag="VXD01_001267"
     tRNA            938..1021
                     /locus_tag="VXD01_001267"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:972..974,aa:Leu,seq:caa)
     gene            complement(1132..1863)
                     /locus_tag="VXD01_001268"
     CDS             complement(1132..1863)
                     /locus_tag="VXD01_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0601663.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GKLWKELTSSEIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYFI
                     DGDVTNSKTIPILCYDTITQKYHFL"
     gene            complement(1856..2092)
                     /locus_tag="VXD01_001269"
     CDS             complement(1856..2092)
                     /locus_tag="VXD01_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HEV0601664.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKAISHEEMMRRYG"
     gene            complement(2308..2745)
                     /locus_tag="VXD01_001270"
     CDS             complement(2308..2745)
                     /locus_tag="VXD01_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0601665.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            complement(2786..3919)
                     /locus_tag="VXD01_001271"
     CDS             complement(2786..3919)
                     /locus_tag="VXD01_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0601666.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYKTKKEAIEAE
                     HYLRSVELKERFYGAKITISILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAGTRRIVINKKLSQELQDWEKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            complement(3923..4126)
                     /locus_tag="VXD01_001272"
     CDS             complement(3923..4126)
                     /locus_tag="VXD01_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEV0601667.1"
                     /translation="MIATVTKNDLIALGFSEGTSKRIIRQGKELLITRGFTVYQNKRI
                     GTIPATIATELLGFDVQNSTLKE"
     gene            complement(4140..4922)
                     /locus_tag="VXD01_001273"
     CDS             complement(4140..4922)
                     /locus_tag="VXD01_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HEV0601668.1"
                     /translation="MTSYNKKIVRTSSYIEIWEYEKPIFSKGKSILDTNTENKEKAKR
                     RTFDELTPLEQEQRLERMKKTRLEAKWNLLRLVDCNFDDTTSFLTLTTKENISDRNHF
                     KDLLKTFIKRFNYHIFNTKKSKLKYIAVLERQKRKAWHSHILLFSVPYIPHKQLLELW
                     GHGAVRINKVDVDSKENRGRYVTKYFEKGIGQELLENFGKQAYFSSRNLKKPDEDKFY
                     TYEDFNYDSSVVLYETEYTSKVYKDGQYFDNHVKYKKIRLDE"
     gene            complement(5020..5793)
                     /locus_tag="VXD01_001274"
     CDS             complement(5020..5793)
                     /locus_tag="VXD01_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV0601669.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIDVINLIGNHDAYYLLGEQAPFSIQNLEVFFAI
                     QQLLQDLNLQVAYQLDDYLVSHAGFNLIFDPKEWHFNLYTKEHEEELDILAYTIGPMR
                     GGKALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHFEVISTDWATDKILKQLPQPQI"
     gene            complement(5960..6349)
                     /locus_tag="VXD01_001275"
     CDS             complement(5960..6349)
                     /locus_tag="VXD01_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006268423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601670.1"
                     /translation="MQTFNYDDFKNEKGIVSFSEAEQIYSSLLNSSNQLDKEFQEEWT
                     TFVLLCVEYASARGKWLTLSREEKLANDESRTVTHNKVIYQLKILKGLASEQGNDVAW
                     FEQFNDDRKRIGDFACYVAYIYALNAR"
     gene            complement(6507..7190)
                     /locus_tag="VXD01_001276"
     CDS             complement(6507..7190)
                     /locus_tag="VXD01_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEV0601671.1"
                     /translation="MFKLRQSADLTRNNIISCYKLKIMHWLILSISACILFSTIVNIR
                     APTFVQILFIFLGGFIIYKIHLKIKIFRYDLEHYLIIRESLLYVLHTNRLYTTYKDST
                     GQEKVIRSAILEYELDRQKGHVLIKALIRGDEFSHKLKSLEDELCGVLELELEKKVLR
                     PSVAEYHFYYIKPKRLVLQSHNQRQEIDSLDIDLGYGVNYNPIKCPHILVSGGTGRGK
                     SVFISFLIA"
     gene            complement(7196..7414)
                     /locus_tag="VXD01_001277"
     CDS             complement(7196..7414)
                     /locus_tag="VXD01_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601672.1"
                     /translation="MSDNLKAYIFLLGFLILAGIAIFILPQGHFFSVSALVLGCIPLF
                     ISIYYFAKIKLLGFYELLKELLDKIKGI"
     gene            complement(7444..8202)
                     /locus_tag="VXD01_001278"
     CDS             complement(7444..8202)
                     /locus_tag="VXD01_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0601673.1"
                     /translation="MKKIKASTWNINQRSGQGKQIPEMIVHELAKQNSEIVCLTEYVK
                     TDNPSLFCTKLQDMGYKIFEDVRTIDFGNQILIAIKNDLVNDCQVITIDNDDNNPNFL
                     HVRVTIEGQELNIIGVRIKVGGENIFQDFKHRKSQLDKLISNLPATHENTIVLGDFNN
                     GYFQQNDDIHSYQGKAREFYSYPLLKSEMNKAGLTVHTPSEETSWKYCKLDHIFANIP
                     ISNENYSWEFLKNADYNSRVGFPDHAILSASISL"
     gene            complement(8220..8452)
                     /locus_tag="VXD01_001279"
                     /pseudo
     CDS             complement(8220..8452)
                     /locus_tag="VXD01_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000982220.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8735..9196
                     /locus_tag="VXD01_001280"
     CDS             8735..9196
                     /locus_tag="VXD01_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601674.1"
                     /translation="METRNEKFRRLSEARMTKVFSILNILRNQSDKSKYTFSKSDIEE
                     LFGALEQKGEEIKEFFTSPITIKTINLKKSFHYSMVDTSNDKEVAFKKLSTARVEKIF
                     SLMNLLANLSNKSNYNYSDWEVEELFSAYDEEVRKCKVFFEEKRTVFKYSE"
     gene            9472..10749
                     /locus_tag="VXD01_001281"
     CDS             9472..10749
                     /locus_tag="VXD01_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV0601675.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKFLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            10825..12309
                     /locus_tag="VXD01_001282"
     CDS             10825..12309
                     /locus_tag="VXD01_001282"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV0601676.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALCEKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPVRHKTTVAAADMQAAVEAYLGL"
     gene            12370..13650
                     /locus_tag="VXD01_001283"
     CDS             12370..13650
                     /locus_tag="VXD01_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0601677.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYEKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            13654..14274
                     /locus_tag="VXD01_001284"
     CDS             13654..14274
                     /locus_tag="VXD01_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV0601678.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            14440..15582
                     /locus_tag="VXD01_001285"
     CDS             14440..15582
                     /locus_tag="VXD01_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV0601679.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETTRPVEEATPQETTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVAERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            15988..16326
                     /locus_tag="VXD01_001286"
     CDS             15988..16326
                     /locus_tag="VXD01_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0601680.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            16337..16695
                     /locus_tag="VXD01_001287"
                     /pseudo
     CDS             16337..16695
                     /locus_tag="VXD01_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            16802..17419
                     /gene="pcp"
                     /locus_tag="VXD01_001288"
                     /pseudo
     CDS             16802..17419
                     /gene="pcp"
                     /locus_tag="VXD01_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(17447..18304)
                     /locus_tag="VXD01_001289"
     CDS             complement(17447..18304)
                     /locus_tag="VXD01_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV0601681.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            18434..19576
                     /gene="tgt"
                     /locus_tag="VXD01_001290"
     CDS             18434..19576
                     /gene="tgt"
                     /locus_tag="VXD01_001290"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV0601682.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            19674..21491
                     /locus_tag="VXD01_001291"
     CDS             19674..21491
                     /locus_tag="VXD01_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV0601683.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGIVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            21644..22795
                     /gene="nagA"
                     /locus_tag="VXD01_001292"
     CDS             21644..22795
                     /gene="nagA"
                     /locus_tag="VXD01_001292"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV0601684.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            22958..24016
                     /locus_tag="VXD01_001293"
     CDS             22958..24016
                     /locus_tag="VXD01_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0601685.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(24065..25320)
                     /locus_tag="VXD01_001294"
     CDS             complement(join(24065..24102,24102..25320))
                     /locus_tag="VXD01_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0601686.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQLYQLLLFHFQNKEPEKFFGL
                     IEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRN
                     FENFKKRIFIALNIKKERTNFVLSRA"
BASE COUNT         7512 a         4364 c         5285 g         8203 t
ORIGIN      
        1 tagggagttt agctcagctg ggagagcatc tgccttacaa gcagagggtc agcggttcga
       61 tcccgttaac tcccatttta gcgggtgtag tttagtggta aaactacagc cttccaagct
      121 gttgtcgcga gttcgattct cgtcacccgc tttgaacttt gttctttgta ccaagttttt
      181 gacttgggcg cgtagctcag gtggttagag cgcacgcctg ataagcgtga ggtcggtggt
      241 tcgagtccac tcgtgcccat agtgtttagt ccattactag gggattggaa tattatctgt
      301 tcactaagag gacacgggct tgttcccgta taaactattt tggaggatta cccaagtccg
      361 gctgaaggga acggtcttga aaaccgtcag gcgtgtaaaa gcgtgcgtgg gttcgaatcc
      421 cacatcctcc ttttatatta acgcgggatg gagcagctcg gtagctcgtc gggctcataa
      481 cccgaaggtc gtaggttcaa atcctgctcc cgcaataagg ctcggtagct cagttggtag
      541 agcaatggat tgaagctcca tgtgtcggcg gttcgattcc gtctcgcgcc atttatatat
      601 tttggaaggg tagcgaagag gctaaacgcg gcggactgta aatccgctcc ttcgggttcg
      661 ggggttcgaa tccctcccct tccattttac gggcatagtt taaaggtaga actaaggtct
      721 ccaaaacctt cagtgtgggt tcaattccta ctgcccgtgt taatagaatt atggcgggtg
      781 tggtgaagtg gttaacacac cagattgtgg ctctggcatg cgtgggttcg atccccatca
      841 ctcgcctatt ttatattggg gtatagccaa gcggtaaggc aagggacttt gactccctca
      901 tgcgttggtt cgaatccagc taccccagtt actatttgcc ggcgtggcgg aattggcaga
      961 cgcgctggac tcaaaatcca gtgtccgcaa ggacgtgccg gttcgacccc ggccgccggt
     1021 atagttgaaa agacaaggtt tctaagcctt gtctttttgt tatgtcataa gaaatttctt
     1081 ggaattgtta ctaataatta ctaatttcat ataaaagcac atgattaaaa gttatagaaa
     1141 gtgatatttt tgggtaattg tatcatagca aagaataggt attgttttgc tattcgttac
     1201 atctccatca ataaaataat gacttttact atcatagtaa atcttaccca ggtatcttct
     1261 atctttagct acttcccaag aagcaatatg gcccgaaata atagctttat gaaatctacc
     1321 agtggtaata ggaaatttgt ttgtaaatat ctctgaactc gttagttctt tccaaagctt
     1381 tccggcttct tcatcaatgc cagcatgaac aaaaatttgg gtatcagttt cataatagcg
     1441 tttatcccta tatcgttttt taaaccagtt tataaatgga ttgaatttga tattattttt
     1501 aatttcattt ctaacacctg tttcaaagtt gttagcattc gatttaaaaa tatagttcaa
     1561 ttcctctgga gagaagaagc tttttattgt ttctggaaat gctgaagcag taggcttatc
     1621 taaaatcaac caatcataaa accattcttc atgattccct agaagagtaa taatttgatt
     1681 aggataaact tcctcaagtt cgattatttt ggaaatgact tgaaaagatt gaagtccatt
     1741 atcaagataa tctcctagta aaaataggcg attatcttta tcgtttaaat ttactttatt
     1801 gagagcgtct ctgaattcat ccaagtatcc atgtatatca gatattgcgt ataatttagc
     1861 catagcgtct catcatttct tcatgtgaga tagctttttt gccacattca acccattttt
     1921 tataagcttc atcagcgacc ttaatatcat acatatcttc aattttctct ataacagctt
     1981 gtctaataaa gtcagtcttt gttgtattat tttcttcaac aatagcattt aataaagaat
     2041 ttaactcttg actaagttga atagaaattt gtgtagtaac aacattattc atataacagc
     2101 cacctaatag ttattttaga tacattatac tcctagtcta aaagtttctc aataaaaaat
     2161 ttcacttttt atagttattt attttaataa aattgtagta tctgcaagga tgtgccagtt
     2221 cgagaccgac cgccagtata gtaataaaga caaagtttat aagccttgtc ttttgttttc
     2281 tctttataaa attttatagt ttagttacta actttttttc tttgctctta aaaatctaat
     2341 agcagaactg tatttcttat ttctctctaa gtctttttca gtaattaatg gtagtcttgt
     2401 taaatctgaa ttatgccgta aatccgccaa ctttacaact ctagcgagtt catttttctt
     2461 tactagattg agataagatt gataatcttg tccttttttc tttgtgagta tatcgacggc
     2521 ttctataatg ttttttgaaa aaccttcctt ttttaggtct agtagggtta gtgaagtatc
     2581 ttcaattaca tcatgtagat aggcgacagc tttctcttca tcagttgcga caaaactagc
     2641 tactgtttca gggtgtttaa tgtagtcaat tcctgctcta tcaatttgtc caaagtgtgc
     2701 ttttttagct acttcatgtg cttttattac ttgtgatgta tccatgattt aattataaac
     2761 tttccattta taaaactcaa ttactttata gtaaatcatc tagtttatca gctaaatcct
     2821 tttgcttact tgggtacaag tgagagtagg tatcaatcgt ggttgttata gaagcatgtc
     2881 ctagtcgctc ttttacaact agataatctt ccccttggtt aatcagcagg gaagcgtgtg
     2941 agtgcctaaa atcgtgtatg cgtatctttt ttagtgtgct atcacgttca atgattttct
     3001 tgtactgctt ttcaatagca tttttcgtaa ttgtgatagg actattttga aacacttgta
     3061 atgttaggct attgttggta aattgctcta atagatgttt ttgtcgcttt tcccaatctt
     3121 gtaattcttg gcttaatttt ttattgataa caattcttct tgttcctgct ttagtttttg
     3181 ttgtgctgat atgagttact cctttattaa catagacaga tttcgtgata tgaattgtat
     3241 tacttgaaaa gtcgatgtct tgccatgtta gggcaagagc ttccccaagt cttaatcctg
     3301 taaagaatag aacagtaaag agtagtttga tattgtattc ttcgggttca aatagtgtca
     3361 aaaacttctg aaattctttg actgtccaaa attgcatttt tgttttttca attggcaact
     3421 tttttatcaa ttttgctgga ttggaggagt aatagccttt tcgcaaacca acatcaaaaa
     3481 tttttttgag taaaatcatg attttgttaa tagtatttgt gcttaacggt ttatcagaat
     3541 ttttagctac tttttgccta agatgttctc taaattggta gatgtcttca taggttagtt
     3601 ttccgacatt atcgaccata gaaaaataat ctttgatgtg tttgttgtaa ttattatctt
     3661 gtgtattgat atagcttgct tttcgatgat ttatgctatc ttcttcctta agtagttcat
     3721 atagtatgga gatagttatt ttagccccat agaagcgttc ttttaactct acacttcgta
     3781 agtagtgttc tgcttcaata gcttcttttt tcgtcttata gccctttctg acaagtctac
     3841 gttgctttag tgttattggg tcaaaaccgt tgctaatatc aactacccaa ttaccgtctt
     3901 taccttttct aattgccata ttttactcct tgagggtact gttttgaaca tcaaaaccga
     3961 gtaattcggt agcaatagta gcaggtatag taccaattcg cttgttctga tagactgtaa
     4021 agcctcgggt tataagtagc tctttccctt ggcggataat acgtttagat gttccttcag
     4081 agaaaccgag ggcaattagg tcattcttag taacagttgc tatcatgtga cttactcctt
     4141 tattcatcta gtcttatttt cttgtacttt acatgattat cgaaatactg accgtcttta
     4201 tagaccttac tagtgtattc cgtttcatat agtacgactg aactatcata gttaaaatct
     4261 tcataagtgt aaaatttatc ttcatcaggc tttttcaagt tgcgtgatga aaaatatgct
     4321 tgctttccga agttttccaa caattcttgt ccaatacctt tttcaaaata ctttgtgaca
     4381 tatcgaccgc gattttcttt gctgtcaacg tcaactttat ttatccgtac tgctccatgc
     4441 ccccaaagtt ctaataattg cttatgtgga atatagggaa cactgaatag caaaatatga
     4501 ctatgccatg ctttacgttt ttgcctctct aatactgcta tatattttaa tttacttttc
     4561 ttggtattaa aaatgtgata gttaaagcgt ttaataaatg ttttgagtaa gtctttgaag
     4621 tggtttctat cgctgatatt ttccttagtg gtcaatgtaa gaaaagaagt tgtatcatca
     4681 aaattacaat caactagacg gagtaagttc cacttggctt ctaagcgagt cttcttcata
     4741 cgttcaagac gttgttcttg ttctaggggt gttagttcat caaatgttct gcgttttgct
     4801 ttttccttgt tttcagtatt agtatctaaa atagattttc cttttgaaaa tattggcttt
     4861 tcatattccc aaatttcaat ataggaagaa gtgcggacta tttttttatt atatgaggtc
     4921 atatatcatg tgatcctaag caccgctccg ctaaacacac ttccagcttg ctgactgctt
     4981 gtcggcagtt ttgcttaggt acatgatgag aagtagctat taaatttgtg gttgtggtaa
     5041 ttgttttaat attttgtctg ttgcccagtc tgttgaaatg acctcaaaat gtccttggtc
     5101 ataaacgagc aaatctccgt taccaataaa ttgatattta ttatctttgt caatatataa
     5161 tgaaaaagta tctataccaa taacattttt agaaatatca atagattctt taggggtatg
     5221 tccaacaatt tgtttaggaa agtcttggtt gggaagcagt tctaattctc taaaatgtgc
     5281 ccataaagga gaacccccaa gagctttccc accacgcatt ggtcctattg tataagctag
     5341 aatatctaat tcttcttcat gctctttggt atagaggtta aaatgccatt cttttgggtc
     5401 aaatatcaga ttgaaaccag catggctaac taaataatca tctagttgat aagctacttg
     5461 taaattcaaa tcttgtaata attgttgaat tgcgaaaaag acctctagat tttgaattga
     5521 gaaaggagct tgttctccca gtaaataata agcatcatga ttacctataa gattaattac
     5581 atctattcca ttttgctctt tatctatttt ccaagagtat aaaaaagtga ggtctttggc
     5641 ataaagttgg atattgttag tttgaccatg taaatcaacg tagtcaccaa gaaaaatgat
     5701 tctcttaata ttatgtgttt ggataatttt gtcaacaatg ggtaaaatca gttgagattt
     5761 taagtgtaaa tcaccaatta ataacgtctt catatatatt cccctcttta tttttgatat
     5821 tagtctaaga atcgaattaa gttatagcac attgtttcgg tgatagataa aaagaattaa
     5881 ttattcttaa gatgttattt aataatttcc atgaatatca gaaatagagt aatatatagc
     5941 cataatatcc tctaattgtc tatcgagcat ttaaggcata gatataagct acatagcaag
     6001 caaagtcgcc aatacgtttt ctgtcatcgt taaattgttc aaaccaagca acatcattgc
     6061 cctgttcact tgctaaacct tttaaaatct ttagttgata aataacttta ttgtgagtaa
     6121 cagttctaga ttcatcattg gcaagtttct cttctcttga gagtgtgagc catttaccac
     6181 gtgcagaggc atactctacg catagaagta caaatgttgt ccattcttct tgaaattctt
     6241 tatcaagttg attggaggaa ttaaggagac tagaatagat ttgttctgct tcagaaaatg
     6301 aaacaatccc cttttcattc ttaaaatcat cgtagttaaa agtttgcatt gtaaaactcc
     6361 tttatatatt atctaatctt agctattttg ttacaggtaa aacatcagaa caagcgaacc
     6421 acaagtttcc attgaattgc cctacattta aatctttaag agtaacagga caagttttgt
     6481 tgttcgccat ctcttgaaca gaagcactag gcgatcagga aagatatgaa gacagacttt
     6541 cctctccctg tccctcctga tactaaaata tgtgggcatt tgattgggtt ataatttaca
     6601 ccatatccta aatctatatc aaggctatct atctcttgtc tttggttgtg agattgtaga
     6661 actaaccttt ttggttttat gtaatagaaa tgatactctg caacactagg ccgaagaacc
     6721 tttttctcaa gctctagttc aagcacgcca caaagttcat cttcaagaga tttaagtttg
     6781 tggctaaact cgtcccctct tataagagcc ttgataagta catgaccttt ctgtctatct
     6841 aattcatatt ctaagattgc acttctaata actttttctt gtccagtact atctttatat
     6901 gtagtataaa gtctatttgt gtggagtaca taaagtaagc tctcacgtat aataaggtaa
     6961 tgctctaagt catatcgaaa aatttttatt ttcagatgaa ttttatagat aataaatcca
     7021 cctaaaaata tgaagagaat ttgaacaaaa gttggagccc taatattaac aatagtagaa
     7081 aatagaatgc aggcagagat acttagtatc agccagtgca ttatttttag cttataacag
     7141 gaaattatat tgtttcttgt taaatcagca ctttgtctta atttaaacat attagttaga
     7201 taccttttat tttatctaaa agctctttta aaagttcgta aaaccctaag agcttgattt
     7261 ttgcgaaata atagatagaa ataaataatg gaatacatcc aagaacaagg gcagaaactg
     7321 aaaagaaatg cccttgagga agaataaaaa ttgctatgcc agctaatatc agaaatccta
     7381 aaagaaatat atatgctttt aaattatcac tcattttgca ttacctcctc taataaacaa
     7441 gtactataaa gagatagagg ctgatagaat agcatggtct ggaaagccga ctcggctatt
     7501 ataatcagca ttttttaaga attcccaaga ataattttca tttgatatag gaatgtttgc
     7561 aaaaatatgg tctaatttac aatatttcca agaggtttcc tcagagggag tatgtacggt
     7621 taggcctgct ttattcattt cagacttaag caatggataa gagtaaaact ccctagcttt
     7681 gccctgatag gaatgaatat cgtcattctg ttggaaatat ccattattaa agtcacccag
     7741 cacaattgta ttttcatgtg ttgcgggtaa atttgagatt agtttgtcta gttgcgattt
     7801 tcgatgtttg aaatcttgaa aaatgttttc tccaccgacc ttgatacgaa ctccaataat
     7861 gtttaattct tgtccttcaa ttgtcactct aacgtgtaaa aagtttggat tattatcatc
     7921 attatcgata gtaatgactt ggcaatcatt aactaaatca ttctttattg caataaggat
     7981 ttgatttcca aaatcaatag tacgcacatc ttcaaaaatt ttgtatccca tatcctgtaa
     8041 tttagtacag aataaactag gattatctgt ttttacatat tctgtcaagc agacgatttc
     8101 tgaattttgt ttagctaatt catgtacaat catttcagga atttgttttc cttgtcctga
     8161 acgttgattg atattccaag tggatgcttt aatttttttc atatataaac ctttctatgt
     8221 tctgctttac taacgtaaag aagatttatt agatgattgt ttgcaataac aaggtaaaca
     8281 agatttcctg ttctggtttc atactcattt actagctctc tataatgtgc tttatcagtg
     8341 tctatttttc ccattgatta gtgagactag ggctgagtgc aaaaacggta tcaagagtat
     8401 ctaatctatc tcgtgcttct tgatattgtt cagtttttaa tgtattcatc attttgtcct
     8461 ctctttaatg ttaattgagg gagcaaatgc tcctgtgtga tgtatgagtg aaatgaggaa
     8521 gtgctagaag ttgtatccat catagatttc tccaagttct gtaaatataa gaatcctcct
     8581 ttttgtatag tatatttgtg ggatattccc ctatgtttgg tattatacta cagttaaata
     8641 aaaaaatcaa caacaaagat gcaatatttg aaaaaaatct ctccatatga taaaatttaa
     8701 tgtatagcaa tggtaggtaa tgttaggaga aacaatggaa actagaaatg aaaaatttag
     8761 aagattatca gaagctagaa tgactaaggt tttttcaatt ttaaatatat tgagaaatca
     8821 aagtgacaaa tcgaaataca ctttttcaaa atcagacatt gaggagctat ttggagcgtt
     8881 agaacaaaaa ggtgaagaaa taaaagagtt tttcactagc cctattacga taaaaacaat
     8941 caatctaaaa aaatcttttc attattctat ggttgataca agtaatgata aggaagtagc
     9001 ttttaagaaa ttatcaactg caagggtaga aaaaattttt tcactaatga atttacttgc
     9061 aaatcttagc aataaatcga attataatta tagtgattgg gaagtggaag aattgttttc
     9121 agcttatgat gaagaagtaa gaaaatgcaa agtatttttc gaagaaaaga gaacagtatt
     9181 taaatatagt gaataagtca ggaatactaa agtgttacta aaaataaaaa aactatcgtt
     9241 tttgtgatag aggtaacttt ttgaaaaggc tatttgactg gctttatata cttatgaaat
     9301 gttaagagcc caactcaaaa tccagtgtcc gcaaggacgt gccggttcga ccccggccgc
     9361 cggtatagta tagtgttagg aacgttgtta ttcttcgttc cttttttata ttatttttgg
     9421 tataattata gttattcaaa ttttatttag attaagaaag tgtaggggag tatgtcttgt
     9481 tctatcgatt tattaaaaca tcggtatttg aaaaatatta aagaaaatcc tgaattgttt
     9541 gtcggaattg agttggagta tcctgttgca agtttagaag gggatgctac agatgttgaa
     9601 gttataaagg atctatttca ttatttagtt tctactttgg atctcaccgt agcaaaggta
     9661 gatgattttg gcaatctgat ccagttagta gatccgataa gtcaggatgc tattttattt
     9721 gaagtttcct atacaacgat tgagtttgca tttggtaagg ctgaaacgat tcaagaggtc
     9781 gaaaatcgtt tcaataatta tatgaatgta attcagagaa agttagctga atcaaatcat
     9841 gctattgttg gctgtggtat ccatcccaac tgggataaaa atgagaattg tccagtggct
     9901 tatccacgct atcagatgtt gatggattat ttgaatttga gtagaaatat tattaaatca
     9961 gatttacatc atttccctga atatggtact tttatctgtg ggagccaggt tcagctggat
    10021 atttcaaaaa ccaactactt acgggtgatt aatgctttta ctcaaattga agcggctaag
    10081 gcttatttat ttgcaaactc tgagttttcg ggtgcggatt gggatacgaa aatttcaagg
    10141 gatattttct gggaagaatc tatgcatggt atctatccag agaatgttgg ggtcaatgct
    10201 agactcctta atgatgaagc tgattttttt gactatctaa atcattctgc gatttttact
    10261 gcggaacgtg atgggcagac ctattatttt tatcctattc aggctgggga ctatttggct
    10321 acgcctgaaa tccaagcatt tgctctgaat ggggatgagg ttattatttc cccccaagag
    10381 aaggattttg aaactcatcg tagttaccag taccaagact taacgactcg aggaacagtt
    10441 gagtttcgta gtgtgtgtac acagccactt gataggactt ttgcttctgc agcttttcac
    10501 ttgggattat tggttaattt agacaagtta gaagcttact tagaaacagc acctttcttt
    10561 aaagtatttg gttatgatta caagttttta aggagacaat tttctaagaa aaatcttaca
    10621 gatgaggaag aaactacgat tattgaattt tccaaagact tactcctact agctgaggag
    10681 ggactagtgg tgagaaataa ggaagaaatg acctatttac agcctttgag agaagaattg
    10741 agcctataat ttctcttata aagggagaat tttctgaaaa atcatgatat aatggacgag
    10801 actatagata aaggatagag agtaatgaca ttagtttatc aatcaacgcg tgatgccaac
    10861 aatacagtaa ctgccagcca agcaattttg caaggtttgg cgacggacgg cggtttgttt
    10921 acaccggtta cttatccaaa ggtagatttg gactttgaca aattgaaaga tgcttcttat
    10981 caggaagttg ctaagctagt tttgtcagca tttttagatg actttacagc tgaggagttg
    11041 gactactgta tcaacaatgc ctacgatagc aaatttgata ctccagctat tgcaccatta
    11101 gtgaaattag atgggcaata caatttggaa cttttccatg gttcaacgat tgcctttaag
    11161 gatatggcct tgtctatttt gccatacttt atgacgactg ctgctaagaa acatggtttg
    11221 gagaacaaga ttgttatctt gacagcgaca tctggtgaca cggggaaagc tgctatggcg
    11281 gggtttgcgg atgtgcctgg tactgagatt atcgtctttt atccaaagga tggtgtcagc
    11341 aagattcaag agttacaaat gaccactcaa actggcgaca atactcatgt tattgctatt
    11401 gatggtaact ttgacgatgc gcaaacaaat gtgaagcaca tgtttaacga cgtggctctt
    11461 tgtgaaaaat tgactaccaa caagttgcaa ttttcatcag ctaactctat gaacattggt
    11521 cgtctggtgc cacagattgt ttattatgtt tatgcctatg ctcagttggt caagactggt
    11581 gagatcgtgg ctggtgataa gattaacttc acagtaccaa caggaaactt tggaaatatc
    11641 ttggctgcct tttatgccaa acaaattggt ttgccagttg gtaaattaat ctgtgcttca
    11701 aatgacaata atgtcttgac agacttcttt aaaacacgtg tctatgacaa aaaacgtgag
    11761 tttaaggtaa caaccagccc atctatggat atcttggtat cttcaaactt ggagcgcttg
    11821 attttccatc ttttgggaaa taatgctgaa aagacagctg aacttatgaa tgccttgaac
    11881 acgcaaggac aatataagtt gacagacttt gatgcagaga ttttggacct ctttgcagct
    11941 gaatatgcga ctgaggaaga aacggcagca gagatcaagc gtgtttgtga gttagattct
    12001 tatatcgagg accctcatac agctgttgct tcagcagttt ataaaaaata ccaatcggcc
    12061 actggagatg taactaagac agtgattgct tcaacagcta gtccatacaa gttcccagta
    12121 gttgcagtag aagctgtaac tggaaaagca ggtttaacag actttgaagc cttggctcaa
    12181 ttacatgaaa tctcaggcgt tgcagtgcca ccagcagttg atgggcttga aatagctcct
    12241 gttcgtcaca agacaactgt agcggctgct gatatgcaag cagcggttga ggcttattta
    12301 ggactttaag atagagggag taaactcggt tgggaaacca actgagtttc ttttcatcag
    12361 gaggagagat tgtttaagaa aaataaagac attcttaata ttgcattgcc agctatgggt
    12421 gaaaactttt tgcagatgct aatgggaatg gtggacagtt atttggttgc tcatttagga
    12481 ttgatagcta tttcaggggt ttcagtagct ggtaatatta tcaccattta tcaggcgatt
    12541 ttcatcgctc tgggagctgc tatttccagt gttatttcaa aaagcatagg gcagaaagac
    12601 cagtcgaagt tggcctatca tgtgactgag gcgttgaaga ttaccttact attaagtttc
    12661 cttttaggat ttttgtccat cttcgctggg aaagagatga taggactttt ggggacggag
    12721 agggatgtag ctgagagtgg tggactgtat ctatctttgg taggcggatc gattgttctc
    12781 ttaggtttaa tgactagtct gggagccttg attcgtgcaa cgcataatcc acgtctgcct
    12841 ctctatgtta gttttttatc caatgccttg aatattcttt tttcaagtct agctattttt
    12901 gttctggata tggggatagc tggtgttgct tgggggacaa ttgtgtctcg tttggttggt
    12961 cttgtgattt tgtggtcaca attaaaactg ccttatgaga agccaacttt tggtttagat
    13021 aaggaactgt tgaccttggc tttaccagca gctggagagc gacttatgat gagggctgga
    13081 gatgtagtga tcattgcctt ggtcgtttct tttgggacgg aggcagttgc tgggaatgca
    13141 atcggagaag tcttgaccca gtttaactat atgcctgcct ttggcgtcgc tacggcaacg
    13201 gtcatgctgt tggcccgagc agttggagag gatgattgga aaagagttgc tagtttgagt
    13261 aaacaaacct tttggctttc tctgttcctc atgttgcccc tgtcctttag tatatatgtc
    13321 ttgggtgtac cattaactca tctctatacg actgattctc tagcggtgga ggctagtgtt
    13381 ctagtgacac tgttttcact acttgggacc cctatgacga caggaacagt catctatacg
    13441 gcagtctggc agggattagg aaatgcacgc ctcccttttt atgcgacaag tataggcatg
    13501 tggtgtatcc gcattgggac aggatatctg atggggattg tgcttggttg gggcttgcct
    13561 ggtatttggg cagggtctct cttggataat ggttttcgct ggttatttct acgctatcgt
    13621 taccagcgct atatgagctt gaaaggatag gaaatgcaaa aaacagcttt tatttgggat
    13681 ttagacggga ctttattgga ctcttacgaa gcgattttat cagggattga ggagactttt
    13741 gctcagtttt ctattcctta tgataaggag aaggtgagag agtttatctt caagtattcg
    13801 gtgcaaaatt tgcttgtgcg ggtggcagaa gatagaaatc tggatgttga ggtgctaaat
    13861 caggtgcgtg cccagagtct ggctgagaag aatgctcagg tagttttgat gccaggtgcg
    13921 cgtgaggtgc tagcttgggc agacgaatca ggaattcagc agtttatata tactcataag
    13981 gggaacaacg cttttaccat tctcaaggac ttgggggtgg aatcctattt tacagagatt
    14041 ttaaccagtc agagtggctt tgtgcggaag ccaagtccag aagcggctac ctatctgcta
    14101 gataagtatc agttgaattc tgataatact tattatatag gggatcggac tctggatgtg
    14161 gaatttgccc agaatagtgg gattcaaagt atcaactttt tagagtctac ttatgaaggg
    14221 aatcacagga ttcaagcgtt agcagatatt tcccgtattt ttgagactaa gtgataaaaa
    14281 gattgtgtca gttttgtgac agagacctaa caaactattt caagtaacct agtttgttac
    14341 aaggagtaga cagttctgtt aaataggccc gagagggctt tttttctaca ttttttgtgt
    14401 tatgatagac aggtactcat ttgaaaggaa tttgaaagaa tgaagaaaag aatgttatta
    14461 gcgtcaacag tagccttgtc atttgcccca gtattggcaa ctcaagcaga agaagttctt
    14521 tggactgcac gtagtgttga gcaaatccaa aacgatttga ctaaaacgga caacaaaaca
    14581 agttataccg tacagtatgg tgatactttg agcaccattg cagaagcctt gggtgtagat
    14641 gtcacagtgc ttgcgaatct gaacaaaatc actaatatgg acttgatttt cccagaaact
    14701 gttttgacaa cgactgtcaa tgaagcagaa gaagtaacag aagttgaaat ccaaacacct
    14761 caagcagact ctagtgaaga agtgacaact gcgacagcag atttgaccac taatcaagtg
    14821 accgttgatg atcaaactgt tcaggttgca gacctttctc aaccgattgc agaagctcca
    14881 aaagaagtag catcaagttc agaagttaca aagacagtga ttgcttctga agaagtggca
    14941 ccatctacgg gcacttctgt cccagaggag caaacggccg aaacaactcg cccagttgaa
    15001 gaagcaactc ctcaggaaac gactccagct gagaagcagg aaacacaagc aagccctcaa
    15061 gctgcatcag cagtggaagc aactacaaca agttcagaag caaaagaagt agcatcatca
    15121 aatggagcta cagcagcagt ttctacttat caaccagaag aaacgaaagt aatttcaaca
    15181 acttacgagg caccagctgc gcccgattat gctggacttg cagtagcaaa atctgaaaat
    15241 gcaggtcttc aaccacaaac agctgccttt aaagaagaaa ttgctaactt gtttggcatt
    15301 acatccttta gtggttatcg tccaggagac agtggagatc acggaaaagg tttggctatc
    15361 gactttatgg tagcagaacg ttcagaatta ggggataaga ttgcggaata tgctattcaa
    15421 aacatggcca gccgtggcat tagttacatc atctggaaac aacgtttcta tgctccattc
    15481 gatagcaaat atgggccagc taacacttgg aacccaatgc cagaccgtgg tagtgtgaca
    15541 gaaaatcact atgatcacgt tcacgtttca atgaatggat aaacccgact tgataacatc
    15601 attttgacga atgagatcta gctttcgtga tggaaagcga ttctcgttcg ttttttcttt
    15661 gtcatactct tcgaaaatct cttcaaacca cgtcagtttt atatgaaacc tcaaagctgt
    15721 gctttgagca acctgcgact agcttcctag tttgctcttt gattttcatt gagtatcaat
    15781 ttgaatggaa aatggaaagt tattatcttg taataatcca agcaacattc ttgcaatcta
    15841 ttttacttta tatcacaatt gattggtcaa ctattgataa gtcaatggat aggaggaaga
    15901 aatgatagag attcaagatt tactgtatca actccgcttg tctgagcaag cgagtacgca
    15961 attgtttgaa aaaggcttgg gattagtttg acacggtatc agattttact gtttttgctg
    16021 gagcattctc cttgtaacca aatggcggtt caggagcgtt tgaaaattga tcaggctgct
    16081 ttgacacggc atttcaagat tttggaaacg gaaggtttgg tggagcgtca tcgtaatcct
    16141 gaaaatcagc gggaagtgtt ggtagaggct gcgaagtatg ccaaggagca gttagtggtg
    16201 aatccccctc tgcaacatat caaggttaag gaagagatgg aaagtatctt aacagagttt
    16261 gagagaacag aactcagccg tttattaaat aaattggttt tgggtattga aaatatagaa
    16321 atttaaggag aaatagatgt caattatttt aacaacgatc gttgctttgg agcattttta
    16381 tattttttat ttggaaagta ttgccacgca atcagatgcg actagtcgtg tatttaatat
    16441 ggaaaaggaa gaattggctc atccgtcagt aagttcattg ttcaaaaatc aaggaattta
    16501 taaggctctg ctaggagtct ttctcttgta tgtcatttat ttctcacaga atttagaaat
    16561 tgtgactatt tttgtcttat ttgtgattgg tgctgcgact tacggctctt taacagcgga
    16621 taaaaaatta ttttgaagca aggtggatca gctattttgg ccttgattag tattttactc
    16681 tttaaataca cttgaaggtt gattctaatc tcgctaatcc tttttaatcc agaataaggg
    16741 aaatatgtta tacttgtttt taagaaaaaa gtctcattga attggttttg aggagttaga
    16801 aatgaaagta ttagtgacag gttttgagcc cttttgaggc cattaaaggt ttaccagctg
    16861 aaatccatgg tgctgaggtc cgttagctag aggtgccgac agtttttcac aaatctgctc
    16921 aagtattgga agaagagatg aatcgttatc aacctgactt tgtcctttgt attgggcaag
    16981 ctggtggaag aactagtttg acacctgaac gagtggccat taatcaagac gatgcacgca
    17041 tttctgataa cgaagataat caaccgattg accgtcccat tcgcccagat ggtgcttcgg
    17101 cctactttag tagtttgccg attaaagcga tggttcaagc tataaaaaag agggcttacc
    17161 ggcctctgtt tccaatacgg cagggacttt tgtctgcagc catttgatgt atcaggctct
    17221 ctatttggta gaaaagaaat ttccatatgt taaggcaggt tttatgcata ttccttatat
    17281 gatggaacag gtggtgaaca gacagactat tccagctatg agtttagtgg atattcggcg
    17341 agggatagaa gcagcaatcg gcgctatgat agaacatgga gatcaggaac tcaagttggt
    17401 aggcggagaa actcattgat agaaaaaagc ttgagtggaa aaaccttcaa gcttttggac
    17461 gttttcgagc caatactgct cggtaaaaca taattttagt gcattggata taaggtagga
    17521 gtgaaaaact agcaatgcca aaggtaatcc aattgaggaa gtaccaagga agaagctgta
    17581 aatctaggac aaagcgctgg aacttgtagc ccttcataaa ggaacggcta gtttttagga
    17641 ttcgtcttgg tgggacctgt cctaggtcta gactataaca gagaagaaat tccacctgtg
    17701 aataggcata atactgtgga atatagagga tatttcctac aatgatcaag atgagacttg
    17761 caagaaagta gagtccaaag accatgagga aacgctcggt ttcaactgat gagagatcta
    17821 gatttggaaa ctcaggatgt agggtgacga attttttggc taaaaagcta ctataaaaga
    17881 ggaggtaaat cccaagtaaa ttagggatac tccataaaaa gagatagaaa cgtttgagaa
    17941 gtagggtcaa aaaggtttga gaaaagcgct cctcatcaaa gagagctagg ctgtttttta
    18001 cagatggctc cgttttagaa tctttcatga gtgtcagtgt tgcatagacg gaactggtca
    18061 aaagaatagt cccgataaag gagactagta gaggaaagag gtaggtttga agtatttggc
    18121 caagtatgct gaaaaatggc tgttctaaaa cagtcccgtg gatccgagat aagggattaa
    18181 gaaaactaga taagatgacc agcatactgg gaaggatata gaggagaaag agacgggggg
    18241 tgtcagcctg aaaatgtttt gactcctgac gaattgtttt taaatcaatt tttggatagt
    18301 tcattctctt attataccat agttcttata catagttcgt gacagttcct actttttttg
    18361 ataaaatcat acagtgtgtc cttgggcaca ctgtatgaac tgggactgtc tttcccagct
    18421 tcggaggtaa aaaatgtcag attcaccaat caaatatcgt ttgattaaga aagaaaaaca
    18481 cacaggagct cgtctgggag aaatcatcac tccccacggt acctttccga cacctatgtt
    18541 tatgccagtt gggacacaag ccactgtcaa aactcagtca cctgaagaat tgaaggagat
    18601 gggttcggga attatcctat caaacaccta tcatctctgg cttcgccctg gagatgaact
    18661 cattgcacgc gctggtggtc tccacaagtt catgaattgg gaccagccta tcttgacaga
    18721 tagtggtggt tttcaggttt attctttagc agatagccgt aatatcacag aagaaggagt
    18781 aacctttaaa aatcatctaa atggttctaa gatgttccta tccccagaaa aagccatctc
    18841 tattcagaat aatctgggtt cagacatcat gatgtccttt gatgaatgtc ctcagtttta
    18901 tcaaccttat gactacgtta agaaatcgat cgagcgtacc agccgttggg ctgagcgtgg
    18961 tttgaaggct caccgtcgtc cacatgacca aggtttgttt ggaattgtgc aaggtgcagg
    19021 atttgaagac cttcgccgcc aatcagctca tgatcttgtc agcatggatt tctcaggcta
    19081 ctctatcggt ggtttggcag tgggagaaac ccatgaagag atgaatgcgg tcttggactt
    19141 tacaactcaa ctgctgcctg aaaataaacc tcgttatctg atgggtgtgg gagcgccaga
    19201 tagcttgatc gatggggtca ttcgtggggt ggatatgttt gactgtgtct taccgactcg
    19261 aattgctcgt aacgggactt gtatgaccag tcaaggacgt ttggttgtga aaaatgccca
    19321 gtttgctgag gactttacgc cactggatcc tgagtgtgac tgctacacat gtaataacta
    19381 tacacgcgct taccttcgtc acctgctcaa ggctgatgaa acctttggta tccgcttgac
    19441 tagctaccac aatctttact tcttgcttaa cctgatgaag caagtgcgac aagccatcat
    19501 ggatgacaat ctcttggaat tccgtgagta ttttgtggaa aaatatggct ataataagtc
    19561 aggacgtaat ttctaaaatg gaattgatat aaaaaaatcc taagttttct cttaggattt
    19621 ttcttctttt tttgatagaa taaagtgtac aatgaaagga agaataaact cgtatgcgca
    19681 ttaaatggtt ttccttggtt aggattacag gtttactttt ggtactcttg tatcacttct
    19741 ttcagacgat ctttcctgga ggatttttcg gggtagatgt ctttttcaca ttttcaggtt
    19801 tcctgattac agctctactc attgaagaat tttctaaaaa ccatgagatt gatttgatag
    19861 gattttttag aagacgcttt tatcggattg tgccacctgt ggttttgatg gtcttggtga
    19921 ccatgccttt tactttcttg gttcgccaag actatgttgc tggaattggt ggccagattg
    19981 cgagcgtctt aggctttatg accaacttct atgaactcct aacaggtggg agttatgaat
    20041 ctcagttcat tcctcatttg tttgttcata attggagttt ggcagttgag gttcactact
    20101 atattctttg gggattggca gtttggttct tatccaaaca agctaaatca aatggtcagt
    20161 tgaaggggat agtctttctc ttatctgctg ttgccttctt gatcagtttc ttctccatgt
    20221 ttattggtag ttttctagtg acctcttatt cctctgttta tttctccagt ttaactcatg
    20281 tctatccatt ctttttggga agtatgttag caactattgt aggtgttcgt cagacgactt
    20341 ccctcgtcaa gcagttggat aaaatctggg atttacgaaa gactttggta gtttttggag
    20401 gaggctttgg tttcctagtt cttttgactt tctttgtcaa attcacttat ctttttgcct
    20461 atcttatcgg cttcttgctt gccagtcttg cagctcttgc catgattctg gcggcgcgtg
    20521 tcttacatga aaagacacat catatacagg agccgaagat tatcagcttt ttagcggata
    20581 ctagctatgc ggtttatctt ttccattggc ctttctatat cattttctca cagttgacat
    20641 caaatcttct tgctgtatta ctgactctga tttgttctta tggctttgcc agtctgtcat
    20701 tctatgtatt ggaaccttgg attgcaggca agaacacacc tattttacaa actcttcgtc
    20761 ccctgcctta tattcacgca attcttgtag caggtacagg aatcttgacc atcattgtct
    20821 gcacggtgac cttgttggca ccacaagtgg gagcgtttga gacagacttg actgtcaatg
    20881 gcttgaagca agctgcaaca aatattggcc agaccaaggt gatggcagaa cgggcagatg
    20941 caaacagttt gggaattgct gatggcacta tgttaattgg tgactcagtg gctttaaggg
    21001 caaatacagc actacagaca gctcttcctg gagcacagat taacgcgcag gtcagcgtaa
    21061 caaccaagac cgcaaatgaa atcatgctaa ataatagcca gaataaattt ttacctaaga
    21121 cggtggtcat tgcgactggg gtaaataatc ctgagaatta caaggatgac tgggacagta
    21181 tcgtgaaaaa tcttcctaag ggacaccata tgattttggt gactccttat gagggagata
    21241 agacaaaaga gacctatgcc atcgttgaga aggctgctgc ctatatgaga gaattggcag
    21301 agaagacacc ttacattacg atagcagatt ggaatcaagt tgcgaaagag catccagaaa
    21361 tttgggcagg aacagaccag gttcatttcg ggagtgagag tagcactatc gaagcaggag
    21421 caaaattgta tgcagatacg attgccacag ctttgcagac agctcaagac aagccggtta
    21481 aatcaaaata acttgtatta aaaaagagaa gagttggaga aatccagctc ttttaaaata
    21541 tctccaaaaa ataggtctat accatttaca aataaaaaag aaaggtttat aatgtaattg
    21601 acataataaa ttgcagaatc aatcttttaa ggaggttaac attatgccta actatattaa
    21661 agcggatcag tttttctacc cacacggagt tcgtcgaggt ggttacttgg aacttgtgga
    21721 cggcaagttt gggaaacatg tagagcagat tcctgaaggg gctgaggtga ttgactatac
    21781 aggttatagc attgccccag gtcttgtgga tactcatatt catggatatg caggtgtaga
    21841 tgtgatggac aacaacattg aaggtacatt gcatactatg agtgaaggac ttcttagtac
    21901 cggtgttacc agtttcttac ccacaacttt aacagccact tatgagcaat tgcttgcagt
    21961 cactgaaaat cttggaaacc attataaaga agcaacaggt gctaagattc gtgggattta
    22021 ttatgaaggt ccatatttca cagaaacttt taagggggca caaaatccaa cttatatgag
    22081 agacccgggt gttgaggagt ttcattcttg gcaaaaagcg gcaaatggct tgcttaataa
    22141 aattgccctt gcaccagaac gtgatggggt ggaagacttt gttcgtacag ttacgggcga
    22201 aggtgtgacg gttgctcttg gacattcaaa cgcgactttt gatgaagcca aaaaagcagt
    22261 cgatgctgga gcgagtgttt gggtgcatgc ctacaatgga atgcgtgggt tgactcaccg
    22321 tgaattgggt atggttggag ccatgtacca attgccacat acctatgcag agttgatctg
    22381 tgatggtcac cacgtagatc caaaggcttg cgaaattctt atcaaacaaa aaggaacaga
    22441 aaacatcgct cttatcacag actgtatgac agctggggga ttggaagacg gagattatat
    22501 gttgggagaa ttcccagttg tcgttgcaaa tggaactgca cgcctcaaat cgacaggtaa
    22561 cttggcaggt tctatcctca aactcaaaga tggtttgaag aatgtggtcg aatggggaat
    22621 tgcgaatccg catgaagcag tcatgatggc cagcttcaac ccagctaaat ccgttcacat
    22681 cgatgacgtc tgtggccaaa tccgtgaagg ctacgacgct gacttcatcg tattagataa
    22741 agatttggaa ttggtagcaa cctacctaga tggcgtaaaa cgttatcaag cataagagag
    22801 aaagcagaag ttagagacta acttctgctt ttttatgcag ggtactttac tggtaaataa
    22861 aaagttaaaa aaatcacaaa aaaagcttga agaaacaaag aaaaaggctt acaattgaac
    22921 tataaatatt acaaataaaa aaacggagga gtgctttatg aaagcctata cttatgttaa
    22981 accaggactt gcttcttttg ttgatgtaga caaaccagtt attcgcaagc caacagacgc
    23041 tattgtgcgt attgtaaaaa ccactatttg tggaacagac ctccatatta tcaaagggga
    23101 tgttcctact tgccaaagtg gtaccattct tggccacgaa gggattggga ttgttgaaga
    23161 agttggggaa ggagtttcca acttcaaaaa aggtgacaag gtcttgattt cttgcgtctg
    23221 tgcctgtggt aaatgctact actgtaaaaa aggaatttat gctcactgtg aagacgaagg
    23281 gggctggatt ttcggtcact tgattgatgg tatgcaggct gaatatctac gtgtccctca
    23341 tgcagataat actctttacc atactccaga agacttgtca gatgaagctt tggttatgct
    23401 gtcagacatt ctgcctactg gatatgaaat tggtgtctta aaagggaaag tagaacctgg
    23461 ttgcagcgta gccattattg gttcaggtcc agttggattg gctgctcttt taacagccca
    23521 attctattca ccagctaaat tgattatggt agacctagac gataaccgct tggaaactgc
    23581 cctatcattc ggtgcgactc ataaggttaa ttcttcagac cctgaaaaag ccattaaaga
    23641 aatttatgat ttgacagatg gtcgtggtgt ggatgtcgct atcgaagctg ttggtattcc
    23701 tgcaacattt gatttctgtc aaaagattat cggtgtagac ggaacggttg ccaactgtgg
    23761 tgtgcatggt aaaccagttg aattcgattt agataaactt tggattcgca acatcaatgt
    23821 aacaactggt ttggtatcta caaatacgac tccacaattg ttgaaagcgc ttgaaagtca
    23881 taagattgaa ccagaaaaat tggtaactca ctatttcaaa ctcagtgaaa ttgaaaaagc
    23941 ctacgaagtc ttcagtaagg cagcagacca ccatgccatt aaggtcatta tcgaaaacga
    24001 tatctcagaa gcctaagtag taaaaatatt tggctctttg tcaactgtag tgggttgaag
    24061 tcagctaagc tcgagaaagg acaaaattcg tcctttcttt ttgatgttca gagcgataaa
    24121 aatccgtttt ttgaagtttt caaagttccg aaaaccaaag gcattgcgct tgataagttt
    24181 gatgagatta ttggtcgctt ccaatttggc gttagaatag tgtagttgaa gggcgttgac
    24241 gattttctct ttgtccttta gaaaggtttt aaagacagtc tgaaaaagag gatgaacctg
    24301 cttaagattg tcctcaatga gtccgaaaaa tttctccggt tccttattct gaaagtgaaa
    24361 aagtaagagt tgatagagct gatagtggtg tttcaagtct tctgaatagc ttaaaatctt
    24421 gtcaagaatt tctttatttg ttaagtgcat gcgaaaagta gggcgataaa aacgtttatc
    24481 gctcaattta cgactatcct gttggatgag tttccagtaa cgtttgatag ccttgtattc
    24541 atgagatttt cgttcaaact gattcataat ttgaacacga aaacgactca tggcacggct
    24601 gagatgttgg ataatatgga aacgatctag aacgatttta gcacacggaa aaagctgttt
    24661 agccaagtca tagtaaggac taaacatatc catcgtaatg attttcactt gacaacgaac
    24721 ggctctatcg tagcgaagaa agtgatttcg gatgacagct tgtgttctgc cttcaagaac
    24781 agtgataata ttaagattat caaaatcttg cgcaatgaaa ctcatctttc ccttagtgaa
    24841 ggcatactca tcccaagaca taatctttgg aagccgagaa aaatcatgct caaagtgaaa
    24901 gtcattgagc ttgcgaatga cagttgaagt tgaaatggcc agctgatggg caatatcagt
    24961 catagaaatt ttttcaatta acttttgagc aattttttgg ttgatgatac gagggatttg
    25021 gtgatttttc tttaccaggg gagtctcagc aaccatcatt tttgaacagt gatagcactt
    25081 gaaacggcgt tttctaagga gaattctaga aggcatacca gttgtttcga ggtaagggat
    25141 cttagacggt ttttgaaagt catatttctt cattagactt ccacaatcag ggcaagatgg
    25201 agcctcataa tccagcttag cgataatttc tttgtgggta tccatattga tgatatctag
    25261 aatcttgatg tttgggtctt taatatcgag cagttttgtg ataaaatgta attgttccat
    25321 atgaatcttt ctaatgatgg ttttgtcgct tttcattata ggtc
//
LOCUS       DAVLDI010000031        24986 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLDI010000031 DAVLDI010000000
VERSION     DAVLDI010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24986
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.031"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(316..1215)
                     /gene="galU"
                     /locus_tag="VXD01_001295"
     CDS             complement(316..1215)
                     /gene="galU"
                     /locus_tag="VXD01_001295"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV0601687.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(1237..2253)
                     /locus_tag="VXD01_001296"
     CDS             complement(1237..2253)
                     /locus_tag="VXD01_001296"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0601688.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            2465..2845
                     /locus_tag="VXD01_001297"
     CDS             2465..2845
                     /locus_tag="VXD01_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0601689.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            complement(3019..3444)
                     /locus_tag="VXD01_001298"
     CDS             complement(3019..3444)
                     /locus_tag="VXD01_001298"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0601690.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMIGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(3512..4162)
                     /gene="phoU"
                     /locus_tag="VXD01_001299"
     CDS             complement(3512..4162)
                     /gene="phoU"
                     /locus_tag="VXD01_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV0601691.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKTLLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(4177..4929)
                     /gene="pstB"
                     /locus_tag="VXD01_001300"
     CDS             complement(4177..4929)
                     /gene="pstB"
                     /locus_tag="VXD01_001300"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV0601692.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDNLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(4931..5746)
                     /gene="pstA"
                     /locus_tag="VXD01_001301"
     CDS             complement(4931..5746)
                     /gene="pstA"
                     /locus_tag="VXD01_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV0601693.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(5739..6602)
                     /gene="pstC"
                     /locus_tag="VXD01_001302"
     CDS             complement(5739..6602)
                     /gene="pstC"
                     /locus_tag="VXD01_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV0601694.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(6720..7595)
                     /locus_tag="VXD01_001303"
     CDS             complement(6720..7595)
                     /locus_tag="VXD01_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV0601695.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(7762..9093)
                     /locus_tag="VXD01_001304"
     CDS             complement(7762..9093)
                     /locus_tag="VXD01_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV0601696.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(9094..9801)
                     /locus_tag="VXD01_001305"
     CDS             complement(9094..9801)
                     /locus_tag="VXD01_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0601697.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(9885..10361)
                     /locus_tag="VXD01_001306"
     CDS             complement(9885..10361)
                     /locus_tag="VXD01_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV0601698.1"
                     /translation="MDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSI
                     YFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKSTIWGSTVDKDYALVSCLVAPGFEFEDFELFERADLLATYPEHKEMIEHLTRY"
     gene            10368..10914
                     /locus_tag="VXD01_001307"
                     /pseudo
     CDS             10368..10914
                     /locus_tag="VXD01_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11304..12995)
                     /locus_tag="VXD01_001308"
     CDS             complement(11304..12995)
                     /locus_tag="VXD01_001308"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV0601699.1"
                     /translation="MNTKELIASELASIIDNLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            13131..13577
                     /gene="argR"
                     /locus_tag="VXD01_001309"
     CDS             13131..13577
                     /gene="argR"
                     /locus_tag="VXD01_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0601700.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            13628..16162
                     /gene="mutS"
                     /locus_tag="VXD01_001310"
     CDS             13628..16162
                     /gene="mutS"
                     /locus_tag="VXD01_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV0601701.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDCEGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            16309..18003
                     /gene="patA"
                     /locus_tag="VXD01_001311"
     CDS             16309..18003
                     /gene="patA"
                     /locus_tag="VXD01_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV0601702.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(18333..18602)
                     /locus_tag="VXD01_001312"
                     /pseudo
     CDS             complement(18333..18602)
                     /locus_tag="VXD01_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            18794..20560
                     /gene="patB"
                     /locus_tag="VXD01_001313"
     CDS             18794..20560
                     /gene="patB"
                     /locus_tag="VXD01_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV0601703.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTHVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMGLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            20699..21388
                     /locus_tag="VXD01_001314"
     CDS             20699..21388
                     /locus_tag="VXD01_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0601704.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            21392..21571
                     /locus_tag="VXD01_001315"
     CDS             21392..21571
                     /locus_tag="VXD01_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601705.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            21558..22907
                     /locus_tag="VXD01_001316"
     CDS             21558..22907
                     /locus_tag="VXD01_001316"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV0601706.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            23031..24491
                     /locus_tag="VXD01_001317"
     CDS             23031..24491
                     /locus_tag="VXD01_001317"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV0601707.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            24505..24939
                     /locus_tag="VXD01_001318"
     CDS             24505..24939
                     /locus_tag="VXD01_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV0601708.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     EFNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         7427 a         4884 c         5336 g         7339 t
ORIGIN      
        1 acttatgttc ggctcggttg atttaattta accatgacta ctccaacagt taagtcaaat
       61 ttaaaattat ttattatttt ggaaccatta gaaacaacat agcaaagtta aaataaggct
      121 ttgtccgtac acaacttgaa aaagtgcgca ccgattcggt gcttttttgt tttactatac
      181 taatttattc tactcttatt ttaatgaaaa aacaaataca agtatagcgt tttcattagt
      241 ttttattaaa taggtagatt caagtagaga atttacttaa tttatgtgtg gctaatcttt
      301 atataaatga ttttgttatt ccttctcagt caattctttt ccaagttgga tgaggtaatt
      361 cttcaaatca tctttgactt gtggatgttt gagggcgtag tcgatggatg ttttcatgaa
      421 gccaaacttg tctccgacat cgtaacgagc ccctttgaac tcacgagcaa atacacgttg
      481 tgttttattg agggtgtcga ttgcatctgt cagctgaatt tcatttcctg cacctggagc
      541 ttgcttttcg agaatctcaa aaatttcagg cgtgaggagg tagcgtccga taatagcaag
      601 gtcgctagga gcgtcctctg gagctggttt ttcaacaaag gtttcaacac tgtaaagacc
      661 atcttttcct tcgccttgcg gagcaataac cccgtaagca gatacttcgt catgagggac
      721 tggcatgaca gcgatagtag acgcgtgggt acgctcgtag tcatccatga gttgtttggt
      781 aagtggaaca gccttttcgt ctgtgatatc catcaagtca tcaccaagca taacgacaaa
      841 aggttcattt ccgacgaaag ccttggcttg caaaacagca tctccgagac cgcgtggatg
      901 agtttggcgg ataaaatgca gacgcatgcc agttgtttca tcaactagct tcaaaagatc
      961 tgttttccct ttttctttga ggttatattc caattcgaag tttgaatcaa agtggtcctc
     1021 aatagaacgt tttgatttac cagtgacaac tagaatatct tcaatacctg atttgagagc
     1081 ttcttccacg ataaactgga tagttggttt gtctacgatt ggcaacattt ctttggcaag
     1141 ggccttggtt gctggtaaaa atcgagttcc tagtccagca gcagggatga ctgcctttct
     1201 aacttttgat gtcataaaaa tcctttctat agagggttaa gaccactcat tttctgcttt
     1261 aaattcattg ttcatgatgt cataaatggc atctttgata ttggttccgt gataaataac
     1321 ttggtaaata gcctgtgtaa tgggcatata gactccaagt tcttgggcta gttcataggc
     1381 tgctcgagtc gttgaaattc cttcgattac catgcccata ttagcttcta tatcagctag
     1441 ggattctcct cgtccgagag catctccagc tctccagtta cgagagtgga tggaagttcc
     1501 cgttacgatc aaatctccca caccagataa gccgctatag gtcaatggac tggccccgag
     1561 tgctacccct aggcgggtga tttctgctaa acctcgagcg atgatggctg ccttagcatt
     1621 atcaccaaat ccaagaccat gtaaagctcc agcaccgaca gcaataatat ttttaagagc
     1681 accagcagtt tcaaccccga taacatccgt attggtataa agtcggaagt agtgattact
     1741 aaatagcttc tgaacgtatt gagctgtttg taaatcttta gaagcagcag ttattaaagt
     1801 taggtcacgc acaatggtct cttctgcatg actaggccct gaaacaacga cgatatcact
     1861 acggagatgt tcaggaattt cttcttcaag aatggttgat aatcgtttat ggctatcagg
     1921 ttctaatccc tttgatgcgt gcatgatgat aaccttatgg tccaaggttt gtgcaacttg
     1981 ctgggcaaca agtcgtgtca cttttgttgg gacaacaaac aaaatcgcat ccacatcttt
     2041 caatgtttct gctaagtcgg tgtaggcaat gatattttcg tctagaacga catctttaaa
     2101 gtagtgctta ttagtatggt gtgtattaat ttcattgatt tgctcgggaa gatttcccca
     2161 aatacgtacc tcgtgtccat tgtcatttaa gacttgtgaa agggcggttc cccaagaacc
     2221 aggccccaag acggcgacgg tttgtttttc catgatttcc tccttgatag agttctttct
     2281 cttattctat catattctag gggattttgc acttgcatta ctggggtatg gtggaaaaat
     2341 acacaaaaac cgagacgaag ggataaactc ttagtcttta gttaaagtga gaagaaatct
     2401 gatagatagt ttgattcagt atatgcttat aatagaggta aacaactcag gaggttcttg
     2461 taggttgcga gagtttggcg aaaaaattaa aagattacgt ttggctaaaa aaatcagtcg
     2521 ttcagaattt tgtggtgatg agtctgaatt aagtatccgt caattaatta gaattgaaaa
     2581 tggagaatcc agaccaacac taacaaagtt aaaatatatc gctgaacgtt tgggggttga
     2641 ggattacaag ttgatgccaa gttatataga gttggataag gaatacctag aattgaagta
     2701 ttttttgatg aggactccta catacgaaga tgaaactatc gcccaaaaga aagagagtgt
     2761 tttgataaga tttttgaaga gtattatgat aggctacctg aggaagaaag atttatcatc
     2821 ccaaattatt catatctggc actaacgaac tacacagttc aaaaattacc agaaaagcta
     2881 gttgaaatac tgtccttctg gtgattttgc ttaatttctg atgttcgaga cataattgag
     2941 gagatttgtc ttgatttttt cctaaaaaag ggcagacttc tcccttggtt tgatgctcga
     3001 tttttaaaat aaggtgactt attctgttag gcatgttttc ccctgccctc tagctctata
     3061 tggaacaggg agtatcagat ttatctggca gattgtatca aataaggctt gaaactgttt
     3121 tgaataggcg tatagacttg agaatttgag aatatgtcgt ctagcagtag agacatattt
     3181 tccggcaata tgaaggaaga gacgtcgaaa acgcttgata gtcaaggact ttacttcatc
     3241 accagctagc tgttttaaaa agaggtagag attataagcc agacagccta tcatcatacg
     3301 tacttcattc ttaatcatgg tcgaactatc tgtcttatcc ccaaagaatc ctgctttcct
     3361 ttctttgata aagttttcag cattccctcg ttcacgatag aattgaaaca gctcctcact
     3421 atctacactg cttaaattgg tcaaatgaac ttttttacaa ccataaaaaa gagcacttaa
     3481 tcgtactctt ctcttttaag gattagttga attaattcaa atccactagt tctcctgttt
     3541 ctaggtagac taggcgttca caaatgttag caatgtaatc agcgaagcgt tccagatgcc
     3601 ctatgatata aaggtattgt gttccattgg gaattgaggt ttcttggtct ttcataagtc
     3661 caatgatttc ctttgataag gcataataat attggtcaat ctgttcatct ttttgagcaa
     3721 tactaatagc ttttgaggct tggtgcaaag gaaaggcaac caataaatcg gatagcatgc
     3781 tgagggataa tttacccatt tggtgtaact gttcttcgtc aggggctagt tgattttctt
     3841 ttagttgcaa aacagcttta gcaatgcctg ccatatggtc tcccatacgt tcaaggtctg
     3901 aacaagaaga catgatgcta atcacaaatc gaaggtcaga cacttgtggc tgctgcaagg
     3961 ccaacaaacg ggcacaggtc aattcgatag cgctttgacc ttggttgata gcatgatcct
     4021 tattgataat tagctctgcc atctccttgt ctttggaggc taaggccagt aaggtttttg
     4081 aagctgtttc aaggacaagt tgccctagtc ctaaaaagga ttgttctaat tcatgcaatt
     4141 ctaagtcaaa ttgatttctc ataggttttt ccttccttat ccgaaccgtc ctgaaatata
     4201 gtcttctgtg cgctgatctt ttggattggt aaacacgtca acggtgtctc caaattcgca
     4261 aatttctcct gttaagaaaa aagcagtttt atctgaaata cgtgaagctt gttgcatgtt
     4321 atgggtaaca atgataatcg tataatcctt ttttagttgc tgaatgaggt cttcaatttt
     4381 taaagtggag atagggtcta aggctgaagt cggctcatcc attaacagaa catcaggttc
     4441 tactgctaaa gctcgcgcaa tgcaaaggcg ttgctgctga ccgcctgata aggacatggc
     4501 actcttttta agattatctt tgacttcgtc ccaaatggct gcccctttta aagatttttc
     4561 cactaaggca tctaattgtt ttttgtctcg aataccatgt gtccttgggc cataagccac
     4621 gttatcatag atagacatgg caaagggatt aggctgttga aaaaccatcc ctacacgctt
     4681 gcgtagctga ttaaggttga atttgctact ataaatatct tgctcatcta agaggacttg
     4741 gccttcaata tggcaagaag gaaccaaatc gttcatccga ttaagggttt ttagaaaagt
     4801 tgatttgcca caaccagatg ggcctatcaa ggcagtaatc tgtctttctg gtaattgaat
     4861 cgaaatattt tttaaggctt gaaaatcccc gtaaaataag tctaggtgtc tgactgaaaa
     4921 tgttcccata ctaggaagct cctttcacaa gtttccgaga taataagctt gatagagtat
     4981 ttatcattaa aacagtaata atcaaaatca cgccggtagc ataggcttca ttgacatgta
     5041 gcccctcact tgacagcata tacatatgta gggctagaga acggcctgaa gacatgagac
     5101 tacttggcgt attggtagag gtacctaatg tatacatgag ggcagctgtt tcaccaacga
     5161 tacggccaat agctagtatc actccagcta aaatacctgg catggcaact ggtagaacaa
     5221 ttctaaaaac agtccgtaac ttacctgccc caagtccata acttgcttga cgcatactat
     5281 cactaacaga taaaagggct tcttctgttg agcgaataat gactggcaac accatgataa
     5341 ctgaggttaa gattcctgat aacagagagt attgaaaacc taagaagact acaaagaaga
     5401 gcatgccaaa cagaccaaaa acaatggaag gaatcccaga taaggtatct gaggccaatc
     5461 gcatgatttt aacacaaagg gaatcttttt ttgtatattc cacaagataa aaaccagcaa
     5521 aaatccctat gggcaaggct aaaagaagag caccaaagac cagaataacg gtggaaataa
     5581 tcgctggcat aagggaaatg ttctcagaag tataagtcca agaaaagagg gatagactta
     5641 gatgaggtaa gcctttgatg aggataaaac caatgattaa aaagagagag ccaaaggtta
     5701 aagctgaaaa acaataaacg agaagtttta gcaggtattt actcataaga tgattttcct
     5761 ttcaagtagg caaagtaggc attaatcaag agaataagga aaaagagaac tgctgaggtt
     5821 gcaataaggg cttccctatg ctgacctgat gcgtaagcca tttccagaac aatattggtt
     5881 gttaaggttc tggttcctga aaagagtcca cttggaataa tcggctggtt gcctgccacc
     5941 aaaataactg ccatggtttc acctactgcg cgaccgattc ctaaaataac tgctgataaa
     6001 ataccagatc tcgcagctgg caagatgaca ctaaaaatac tccgttcatg actagctcct
     6061 agagccaagc taccagaata atacgttttg ggaactgttc ggatagcaga ttctgacaaa
     6121 ctgataatgg ttggcaaaat cattattcct aatagtaacg aagcggttag gacactcatg
     6181 ccatttccta aaaagcttct aatccaaggc accaataatt gtaggccgaa aaaaccataa
     6241 acaatagatg gaatggctgc catcaagttg atagctgatt ttaagaagcc atagacgggc
     6301 tttggacaat aataaaccat aaacaccgat gtcaagatgc ctgttggcac cccaatcaca
     6361 atcgctccta aggtaattaa taaggaacca acgatcattg gtaaaatacc atagcttgcc
     6421 ggaatgttcg ttggcgacca atcactgcct aataaaaaac gggcaaagcc gtagttagct
     6481 atgaaaggta agccattact aaaaataaag aaacagatta gcaaaatagc tacaacagct
     6541 actgttgcac tcatgaaaaa aattgcccta aaaactgctt ctttgaaggc ttgttttgtc
     6601 acatcttgtc ctttctagtg aagaaagtaa gggagatacg acacctccct acttgccttc
     6661 tttatcttat tgtacgatga aacgtctgca tctctttaga gatttatgga gcaaacattt
     6721 tatttaatct tgtcccaggt ggttaatttg ccactaaaaa cgtctgcaag ttcagccata
     6781 ctgacttggc ttgccttatt gtcattattg accacaacag caataccgtc taaagcaata
     6841 gcatcatggg tgagactctt accttcttca ggagttaatt ccctagaaac cataccaata
     6901 tcagcggttt tctccttaac agcggtaata cctgctgaag acccattaga ggtaatatca
     6961 atcgtaactt ctggattttc ttttttataa gcttctgcta atttttccat taaagaagat
     7021 actgaagtgg aacctacaac agacaacttg cctgataagt gttggcttgt atattctgtg
     7081 gtttcggttt tagcttcaat aaatttatta tcagtgacca cttgttgacc ttgtttggag
     7141 tggataaagc tgataaaatc ttgacctagc ttggaaagat tagaagacca aacaatgttg
     7201 aagggacgtt gaagagggta ttcaccatct aaaactgtgt ctcgactagc cttgacacca
     7261 tcaatctcta aagccttgac agatttcgtt aaagatccca aggagatgta gccgatagca
     7321 ttagcattcc cttgaactgc tgagagaaca ccttctgtac tattttgaat cacagctgtt
     7381 ttggcagtgt tgtcaatttt tttatcaccg tcttttttga gaatccctgt gatttctgtg
     7441 aaggcacccc gtgttccaga gccattttct cgtgaaatca cctcaatcgt tcctgaagct
     7501 gactgtttgg aagcagctga ctgattgcca caggcaacaa gcccaaatcc tgataagcca
     7561 atggctgcaa gagtaagcat ttttttgaat ttcataataa tcacctttat ctctatgtat
     7621 ttttcttgtg taggcttact acatttatag tctaacaagt ctttgtaaag gtttatccct
     7681 gattcatgta aagattgtgt aaagaatcaa aaaaagccac ttttgaaaaa tggctgctcc
     7741 taaaaatagc tttaaaaatt attagtcctg tgcgaaagat tggttaggaa gaaaaatcgt
     7801 gaagcaactg cctctgccaa gctgactcgt caccgtgact tggccaccta ataattgact
     7861 gagttctttg acaatggcaa ggccaagacc agtgccacca gtttgtctgc ttcgaccttt
     7921 attaactcgg taaaaacgtt caaaaatacg atcctgctct aattgactaa taccaatccc
     7981 tgtatctgat acagaaatct taatgccttc gttcaccttt tgggtcttga cctcaatttt
     8041 tcccccttgt tcagtgtaac ggatggcatt ggataaaaga ttgagtaaga tttgggaaag
     8101 taattgacta tctgatacga gggtgacatc atctggcacc tgcaccttta gctgtaaatc
     8161 cttcttcttg agctgaggtt gcaagctttg agtcaaatcc tgtacaaatt ctgccaaaga
     8221 aagggtcgtc cattgtatag gcatttgttg agccttagat aaggtaagaa gatgctcaac
     8281 aatatgctca agacgcaagc tttctttgta aataatgtct agaaagtcat ccttgagcgc
     8341 ttcttcttca gctgacatcc ccttaatggt ttcagcaaag cccttaatcg aagtaactgg
     8401 tgtcctcaat tcatgggagg catttgagac aaaggctaaa tttaactttt cataagttct
     8461 aatcgttgtt aaatcatata gcaagacgag cacagcttcc acagattggg tggggctaaa
     8521 aacgggaact gctgtcactt ctaaaatcaa gtcaccctca tgaaacccac ttacttcttg
     8581 ttttaacctt gttttttgat caaaggcttg gtgaactaaa tttcgaatat ccatccgttt
     8641 gaggtcatca agtgaactta tgtcgccgtc cacatcggga aaataatgag gcagagagcg
     8701 actggataat aacatctgac cttgagcgga aactaaaaac gtccccatgg ttaggtgcga
     8761 cagaagaacc tccattgttt cggctaggtc cttgtattgc tgatcctgtt gggagacttt
     8821 ggtttttagg ccagacacat actgagccaa agactttaag tcttcttgcc ctttttctaa
     8881 aaagtattca ctactggtca agagaggttg gtgcaaggtc tcaaaagcaa cttcccattt
     8941 ccaaaggcaa aagagccagt agccaccttg tcccaaagaa agggctagaa gaaagagacc
     9001 gatgccttta ctgatccaag ttaatgccat ccctgcaatc agaatgaggc taacacttag
     9061 attgactagc caaaattgaa ggtagcgttt catctataac tccttgaact tataaccata
     9121 accccgaatg gttcgaataa attgaggggc tttaggattg tcttcaattt tttccctcaa
     9181 cttaccaata tgaacgtcca ccaaacgtgt ttcctgccca aagtcatacc cccagatacg
     9241 ttccaaaaga cgctctctag ttagtgtcat gttgggatgt ttcataagat agagcaagag
     9301 ttcaaattct tttggggtca aactcagtaa cttattcgcc ttgtagactt catgacgctc
     9361 agggtatact ttcaaggtcc caaatagcca agaatcgtca gcgatattat ctgaatcatc
     9421 tccttcttgt tctcctttag ttcgcctgag gacagccttg acacgcgcca gcaattctct
     9481 agggctaaaa ggcttggtca ggtagtcatc agcccctaat tccaaggcca aaaccttatc
     9541 aaattcatca cttttcgcag aaaccatcat aattggagtt ttgacgcctt tggctctcag
     9601 tcgcttacaa acttccatgc catctaattg tggtaacatg atatcaagca agataaaatc
     9661 aaagggttct gtttctgcca aagctaaggc cttccgtcca tttgttacca attgagtaga
     9721 aaagccttcc ttacttaaat ggtagtcaag caatttcaga atgtgttctt catcatccac
     9781 taataagact tgttttgtca tctattatct cctattggta acattataac acaattatca
     9841 gaaatcctaa cattgctaaa ttagattaaa tttgcttatc aagactagta tctggtcaaa
     9901 tgctcaatca tctccttgtg ctctggatag gtcgccagta gatctgccct ttcaaataat
     9961 tcaaaatcct caaattcaaa accaggagca acaagacaag aaaccagagc ataatcctta
    10021 tcaactgttg atccccaaat agtgctctta ggaacacagt agtgaagttg ttgccctttg
    10081 gatatgtcca ggcctaaagt gactgcttcg tagtgaccat ctgctgtaat catgtgaaca
    10141 gtaagtgggg atcctgcatg aaaataccag atttcatctg ctgtcaatcg gtgaaaatgt
    10201 gaaggattcg tttcttctaa taagaaataa atactggtat aaagcgccct tcccttacca
    10261 gcaaggttta tagtgtctga agcttttttt gtttgtctaa aatagccacc ttcaacatgg
    10321 ggagctaact ctagagttct tatcaagtct tctttatcca tcggggccaa tgggttgaag
    10381 taactcttgt tcaaagtggt gttacgattt caagaactcc tctcagttct gaggacacgg
    10441 taatgattga tgcgacggaa gtacaaatca atcgccctaa aaaaagaatt agcgaatgat
    10501 tttggtaaaa agaaatttca cgctatgaag gctcaagcga ttgtcacaag tcaagggaga
    10561 attgtttctt tggatatcgc tgtgaactat tgtcatgata tgaagttgtt caaaatgagt
    10621 cgcagaaata tcggacaagc tggaaaaatc ttggctgaca gtggttatca agggctcatg
    10681 aagatatatc ctcaagcaca aactccacgt aaatccagca aactcaagcc gctaacagct
    10741 gaagataaag cctataacca tgcgctatcc aaggagagaa gcaaggttga gaacatcttt
    10801 gccaaagtaa aaacgtttaa aatattttca acaacctatc gaaatcatcg taaacgcttc
    10861 ggattacgaa tgaatttgat tactggtatt atcaatcatg aactaggatt ctagttttgc
    10921 aggaagtcta ttatttggtt aggtgaatta gtgaagcgtt taggcaagtg tctctggtta
    10981 cgacgtaaag aagcataaat cgatcatatt tatgtttctt tactagtgaa acgcctagcc
    11041 aaattaccat agttacgacg tcatgacctc taaatcgatt atatttaggg gtcatgacta
    11101 gtgaagcagt tagctagttc gcatataagc ggctagcgtc taacaattag gaactttagt
    11161 tccaataact ttaagattac gacgttttag gacataaatc gatcatattt atgtcctaaa
    11221 actagtgaag cgcctagcca aagtccgaat aggatttggc gttagttact tagattgctt
    11281 tgcaatcaag taactttggc gatttacatc ttctctggcg cttctactcc aagcaagcga
    11341 agggcttctt tgagaacgac tgcggttgcg tagctgaggg ctagacggct gtcgcgttct
    11401 gggctttcat ccaagatacg tgtatgtgca tagtatttgt taaaggattg agctaggcta
    11461 attgcaaatt tagcaatgat agaaggttca aagttatctg ccgcacggtt gataatacgt
    11521 gggaagtctt gaatgagttt aatgatttcc cagctttcag tatcattcaa gctatagttg
    11581 ccagctgttt ctggtttgaa atcggctttg cgtaagatag attggatacg agcgtaggca
    11641 tattgaacgt aaggtccagt ttcaccctcg aaggatacca tagcctctag gtcgaagtcg
    11701 tatccatttg tacggtcggt tttgaggtca tagaatttaa tggctccaac cccaacagca
    11761 tgtgctactt ggtctttgtt ttctagttca ggatttttag cctcgatttg gaccttggca
    11821 cggctaacag cctctgcaac agtaggctct agcaagatga cattcccttt acgagtagag
    11881 agtttcttcc cttcttttgt aaccaaacca aaaggaacgt gagtaatgtc gtcactccag
    11941 tcgtagccca tctcttgcaa gacagctttg agctgtttaa agtgggcaga ttgttcttga
    12001 ccaacgacat agatagattt agcaaattgg tattcgtttt tacggtaaag ggctgcagcc
    12061 aagtcacgtg tgatatagag agttgcacca tcagatttct tgatgagagc tggatgttca
    12121 attccgtatt tctcaagatt gacaacttgg gcaccttctg attcaagaag tagtcctttt
    12181 tcagaaagaa tgtctacaac tgcatccatc ttatcattgt agaaggcttc tccgttatag
    12241 ctgtcaaatt caaccttcaa ttcattgtaa aggcggttaa attccactaa actttcatcg
    12301 cggaaccatt gccaaagagc gagagcttcc tcatctccat tttcaagttt acggaaccat
    12361 tcgcgcgctt cttcatccaa gctagggtca ttttcagctt cagcgttgat gcggacatag
    12421 agtttaagga gttcatcgat tggatgagct tttacagctt cttcgtcgcc ccattttttg
    12481 taggcaacaa tcaacatccc aaattgttta ccccagtctc ccaaatggtt gaccttgacc
    12541 gtttgataac cgattttttg gaaaatatgt gacaagctat ctccgataac agttgaacgc
    12601 aggtggccaa tagaaaatgg tttagcgata ttcggactag acatgtcgat aacaacattt
    12661 tcttgtttgc caatattttg gtcagcatag tgttcttttt cagtggtaac agcttgcaat
    12721 acttgagcag aaatggcaga tttatcaagg aaaaagttaa cgtaaggtcc tgttgcgaca
    12781 actttttcaa aggcttggct gttcattttt tcagccagtt cagccgcaat catttgtggt
    12841 gctttacgtt cgactttggc aagagaaaaa gcagggaaag cgatgtcacc catttctgag
    12901 tttttagggg tttccagtaa ctttaaaata gcctcttggt ccaggttatc aatgatgcta
    12961 gccaattcgc tagcaatcaa ttcttttgta ttcattaaga gctccttttt ggacttttct
    13021 actattttaa cacaatttta aagaaagaag aaaaaatttt tgaaatctcc tgtttttttg
    13081 gtataatatg gttataaata tagttataaa tatgcacgca agaggatttt atgagaaaaa
    13141 gagatcgtca tcagttaata aaaaaaatga ttactgagga gaaattaagt acacaaaaag
    13201 aaattcaaga tcggttggag gcgcacaatg tttgtgtgac gcagacaacc ttgtctcgtg
    13261 atttgcgcga aatcggcttg accaaggtca agaaaaatga tatggtgtat tatgtactag
    13321 taaatgagac agaaaagatt gatttggtgg aatttttgtc tcatcattta gaaggtgttg
    13381 caagagcaga gtttaccttg gtgcttcata ccaaattggg agaagcctct gttttggcaa
    13441 atattgtaga tgtaaacaag gatgaatgga ttttaggaac agttgctggt gccaatacct
    13501 tattggttat ttgtcgagat cagcacgttg ccaaactcat ggaagatcgt ttgctagatt
    13561 tgatgaaaga taagtaaggt cttgggagtt gctctcaaga cttatttttg aaaaggagag
    13621 acagaaaatg gcgatagaaa agctatcacc cggcatgcaa cagtatgtgg atattaaaaa
    13681 gcaatatcca gatgcttttt tgctctttcg gatgggtgat ttttatgaat tattttatga
    13741 ggatgcggtc aatgctgcgc agattctgga aatttcctta acgagtcgca acaagaatgc
    13801 cgacaatccg atccctatgg cgggtgttcc ctatcattct gcccaacagt atatcgatgt
    13861 cttgattgag cagggttata aggtggctat cgcagagcag atggaagatc ctaaacaagc
    13921 agttggggtt gttaaacgag aggttgttca ggtcattacg ccagggacag tggtcgatag
    13981 cagtaagccg gacagtcaga ataatttttt ggtttccata gactgcgaag gcaatcaatt
    14041 tggcctagct tatatggatt tggtgacggg tgacttttat gtgacaggtc ttttggattt
    14101 cacgctggtt tgtggggaaa tccgtaacct caaggctcga gaagtggtgt tgggttatga
    14161 cttgtctgag gaagaagaac aaatcctcag ccgccagatg aatctggtac tctcttatga
    14221 aaaagaaagc tttgaagacc ttcatttatt ggatttgcga ttggcaacgg tggagcaaac
    14281 ggcatctagt aagctgctcc agtatgttca tcggactcag atgagggaat tgaaccacct
    14341 caaacctgtt atccgctacg aaattaagga tttcttgcag atggattatg cgaccaaggc
    14401 tagtctggat ttggttgaga atgctcgctc aggtaagaaa caaggcagtc ttttctggct
    14461 tttggatgaa accaaaacgg ctatggggat gcgtctcttg cgttcttgga ttcatcgccc
    14521 cttgattgat aaggaacgaa tcgtccaacg tcaagaagta gtgcaggtct ttctcgacca
    14581 tttctttgag cgtagtgact tgacagacag tctcaagggt gtttatgaca ttgagcgctt
    14641 ggctagtcgt gtttcttttg gcaaaaccaa tccaaaggat ctcttgcagt tggcgactac
    14701 cttgtctagt gtgccacgga ttcgtgcgat tttagaaggg atggagcaac ctactctagc
    14761 ctatctcatc gcacaactgg atgcaatccc tgagttggag agtttgatta gcgcagcgat
    14821 tgctcctgaa gctcctcatg tgattacaga tgggggaatt atccggactg gatttgatga
    14881 gactttagac aagtatcgtt gcgttctcag agaagggact agctggattg ctgagattga
    14941 ggctaaggag cgagaaaact ctggtatcag cacgctcaag attgactaca ataaaaagga
    15001 tggctactat tttcatgtga ccaattcgca actaggaaat gtgccagccc actttttccg
    15061 caaggcgacg ctgaaaaact cagaacgctt tggaaccgaa gaattagccc gtatcgaggg
    15121 agatatgctt gaggcgcgtg agaagtcagc caacctcgaa tacgaaatat ttatgcgcat
    15181 tcgtgaagag gtcggcaagt acatccagcg tttacaagct ctagcccaag gaattgcgac
    15241 ggttgatgtc ttacagagtc tggcggttgt ggctgaaacc cagcatttga ttcgacctga
    15301 gtttggtgac gattcacaaa ttgatatccg gaaagggcgc catgctgtcg ttgaaaaggt
    15361 tatgggggct cagacctata ttccaaatac gattcagatg gcagaagata ccagtattca
    15421 actggttaca gggccaaaca tgagtgggaa gtctacctat atgcgtcagt tagccatgac
    15481 ggcggttatg gcccagctgg gttcctatgt tcctgctgaa agcgcccatt taccgatttt
    15541 tgatgcgatt tttacccgta tcggagcagc agatgacttg gtttcgggtc agtcaacctt
    15601 tatggtggag atgatggagg ccaataatgc catttcgcat gcgaccaaga actctctcat
    15661 tctctttgat gaattgggac gtggaactgc aacttatgac gggatggctc ttgctcagtc
    15721 catcatcgaa tatatccatg agcacatcgg agctaagacc ctctttgcga cccactacca
    15781 tgagttgact agtctggagt ctagtttaca acacttggtc aatgtccacg tggcaacttt
    15841 ggagcaggat gggcaggtca ccttccttca caagattgaa ccgggaccag ctgataaatc
    15901 ctacggtatc catgttgcca agattgctgg cttgccagca gaccttttag caagggcgga
    15961 taagattttg actcagctag agaatcaagg aacagagagt cctcctccca tgagacaaac
    16021 tagtgctgtc actgaacaga tttcactctt tgatagggca gaagagcatc ctatcctagc
    16081 agaattagct aaactggatg tgtataatat gacacctatg caggttatga atgtcttagt
    16141 agagttaaaa cagaaactat aaaaccaaga ctcactagtt aatctagctg tatcaaggag
    16201 acttctttga caattctcca cttttttgct agaataacat cacacaaaca gaatgaaaag
    16261 gagctgacgc attgtcgctc ccttttgtct attttttaag gagaaagtat gctgattcag
    16321 aaaataaaaa cctacaagtg gcaggccctg gcttcgctcc tgatgacagg cttgatggtt
    16381 gctagttcac ttctgcaacc gcgttatctg caggaagtct taggcgccct ccttactggg
    16441 aaatatgaag ctatttatag tatcggggct tggttgattg gtgtggccgt agtcggtcta
    16501 gttgctggtg gactcaatgt tgtcctcgca gcctatattg cccaaggagt ttcatccgac
    16561 cttcgggagg atgccttccg taaaattcaa accttttctt atgctgatat tgaacaattt
    16621 aatgcgggaa atctagtcgt tcgaatgaca aatgatatca accagattca gaacgttgtc
    16681 atgatgacct tccaaattct tttcagactt cccctcttgt tcatcggttc gtttatccta
    16741 gcggttcaaa ccttaccttc tctgtggtgg gtgattgttc tcatggtagt cttgattttt
    16801 ggtttgactg ctgtcatgat gggaatgatg gggcctcgtt ttgccaagtt tcaaaccctt
    16861 cttgagcgca tcaatgccat tgccaaggaa aatttacgtg gcgttcgtgt ggtcaagtcc
    16921 tttgtccaag aaaaagagca atttgctaag tttacagagg tctcagacga gcttcttggt
    16981 caaaaccttt acattggtta tgccttttca gtagtggaac cctttatgat gttggttggt
    17041 tacggggcgg tcttcctctc tatttggctg gtcgcgggaa tggttcagtc ggatccgtct
    17101 gttgttggtt ccatcgcttc ttttgttaat tacctaagcc agattatctt taccattgtt
    17161 atggttggat ttttgggaaa ttctgtcagc cgtgccatga tttccatgcg tcgtattcga
    17221 gaaattcttg acgcagagcc agctatgacc ttcaaggata tcccagatga agagttggtt
    17281 ggaagcctta gctttgaaaa tgtgaccttt acctatccaa tggacaagga accgatgctg
    17341 aaagatgtga gctttactat tgaacctggt caaatggttg gtgtagttgg agcgactggt
    17401 gcaggaaagt caaccttggc tcaattgatt ccacgtctct ttgatccaca ggaaggggct
    17461 atcaaaatcg gaggtaagga tattcgagaa gtgagtgaag gaaccctgcg taaaacagtt
    17521 tccatcgttc tccaacgtgc cattcttttt agtggaacga ttgcagataa cttgagacag
    17581 gggaagggaa atgctactct atttgaaatg gagcgcgcag ccaatattgc ccaggctagt
    17641 gaattcattc atcgtatgga gaaaaccttt gaaagtccag ttgaagaacg gggaaccaat
    17701 ttctctggtg gacaaaaaca aaggatgtcg attgcgcgtg ggattgtcag caatccacgt
    17761 attctgattt ttgatgattc gacctcagcc ttggatgcca aatcagagcg cttggtgcaa
    17821 gaagctttga ataaggactt gaaggggacg acaaccatta ttattgctca aaaaattagc
    17881 tcggttgtcc atgcagacaa gatcttggtt ctaaatcaag gacgattgat tggtcaaggc
    17941 acgcatgcag acttggttgc caacaatgcc gtttaccgtg aaatctatga aacacagaaa
    18001 tgaaagacaa actataagaa aagtcaatag ttttatctaa actatttctt atttcaattt
    18061 gatgatttgg cgatgatttt agagcacggc aaaaagctat tgaaaaagtc cattttttca
    18121 aaggtaatcc tgtgttaatt tcagaaatta tatcactttt tgttcgtcaa atggcagctc
    18181 ttttttagga tataaaacag ggttcggata agtttttttg caaggtggat gatggctaca
    18241 ttgtaatgtt ttccttattc taacttagtc ttaagatagg ccttaaaagc aggtgaaaag
    18301 cgagggcatg ctttggcagc ttgtatgagt acctaccgca gatgagggga accccgtttg
    18361 accattcttc ctgctaaatc aatctgacct gactgataaa tagaagaatc cagtccagcg
    18421 aaagcttgta attgagcagg attatcaaag gcatgaatat ttcgaatctc ggctaaaatg
    18481 accgccccta aacgattctc aatcccagta accgtcgtga tgaccgagtt gaactcagcc
    18541 atcaagtcat tgacacattt tttcgccttg tcaatgagcc tcttgtaatg tttgatgatt
    18601 tcattacacg agataaaacg tctatgcgtt atcaaactca ttaccaatta aaacaaaaag
    18661 ctgtggttag atcctttcgg aaatcgtcaa gcgattggag gaaatgaact aatccacagc
    18721 ggcttattcc aagtatacca cttgggcttt ggcagtagct aactgcgcta aatataatat
    18781 aaggaggagt aaaatgaaga cagttcaatt tttttggcat tattttaagg tctacaagtt
    18841 ctcatttgta gttgtcatcc tgatgattgt tctggcgact tttgcccaag ccctctttcc
    18901 agtcttttct ggacaagcgg tgacgcagct agccaattta gttcaagctt atcaaaatgg
    18961 caatccagaa cttgtatggc aaagcctatc aggaatcatg gtcaatcttg gcctgctggt
    19021 tttggttcta tttatctcta gtgtaatata catgtgtctc atgacgcacg tgattgcaga
    19081 atcgaccaac gagatgcgca aaggcctctt tggtaagctt gctcagttga cggtttcttt
    19141 ctttgaccgt cgacaagatg gcgatatcct gtctcatttt accagtgatt tggataatat
    19201 cctccaagcc tttaacgaaa gcttgattca ggtcatgagc aatattgttt tatacattgg
    19261 tctgattctt gtcatgtttt cgagaaatgt gacgctggct ctcatcacca ttgccagcac
    19321 cccattggct ttccttatgc tgattttcat cgtgaaaatg gcacgcaaat acaccaacct
    19381 ccagcagaaa gaggtaggga agctcaacgc ctatatggat gagagcatct caggccaaaa
    19441 agccgtgatt gtgcaaggaa ttcaagagga tatgatggca ggatttcttg aacaaaatga
    19501 gcgcgtgcgc aaggcaacct ttaaaggaag aatgttctca ggaattcttt tccctgtcat
    19561 gaatgggatg ggcctgatta atacagccat cgtcatcttt gctggttcgg ctgtactttt
    19621 gaatgataag tctattgaaa caagtacagc cctaggtttg attgttatgt ttgcacaatt
    19681 ttcacagcag tactaccagc ctattatcca agttgcagcg agttggggaa gccttcagtt
    19741 ggcctttact ggagctgaac gaattcagga aatgtttgat gcagaggagg aaatccgacc
    19801 tgaaaaggct ccaaccttca ctaagttgca agaaagtgtt gaaatcagtc atatcgattt
    19861 ttcatacttg cctgataaac ctattttgaa agatgtcagc atttctgccc ctaaaggcca
    19921 gatgacagca gttgttgggc cgacaggttc aggaaaaacg actattatga acctcatcaa
    19981 tcgcttttat gatgttgatg ctggtggtat ttattttgat ggtaaagaca ttcgtggcta
    20041 tgacttagat agtcttagaa gcaaggtggg aattgtattg caagattcgg tcttgtttag
    20101 cggaacgatt cgagacaata tccgatttgg tgtgccagat gctagtcagg aaatggttga
    20161 ggtagcagca aaagcaaccc acattcacga ctatatcgaa agtttgcctg ataagtacga
    20221 tactcttatt gatgatgacc agagcatctt ttcaacaggg cagaagcaat tgatttcaat
    20281 cgctcgaacc ctgatgacag atccagaagt tctcattctc gatgaagcaa cttcaaacgt
    20341 agatacggtg acagaaagca agattcagca tgccatggag gtggttgtag caggtagaac
    20401 tagtttcgtc attgcccacc gcttgaaaac cattctcaat gcagatcaga ttattgtcct
    20461 taaagatgga gaagtcattg aacgtggtaa ccaccatgaa cttttgaagc taggtggctt
    20521 ttattcagaa ctctatcaca atcaatttgt tttcgaataa gaaagaagtt gtcctatgtg
    20581 ggcagctttt tcttgtccat aaaaaatgtt tatcacagcc ttaaaaaaaa catattagac
    20641 gaaagtcatt ttgagtgata tgataggact atcgttagca ttcgaaagga gaggcatcat
    20701 ggctagaacg gttgtaggag ttgctgcaaa tctatgtccc gtagacgcag aaggcaaaat
    20761 cattcattca tctgtatctt gtagattcgc agagatcatt cgtcaagtcg gtggtctccc
    20821 tttagtcatt cctgttggtg atgagtcagt tgtacgtgat tatgtggaaa tgattgacaa
    20881 actcattttg acaggaggcc aaaatgttca tcctcagttt tatggagaga aaaagaccgt
    20941 cgaaagcgat gattacaatc tggtccgtga cgaatttgaa ttggcactct tgaaggaagc
    21001 gcttcgtcag aataaaccaa ttatggcaat ctgtcgcggt gtccaacttg tcaatgttgc
    21061 ctttggtgga accctcaatc aagaaatcga aggtcactgg caaggactac ctttcgggac
    21121 atctcactct attgagacag tagaaggaag cgtggtggct aagctatttg ggaaagaaag
    21181 tcaggtcaac tcagtccatc gtcaaagcat taaagatttg gcacctaatt tccgtgtaac
    21241 tgccattgat tcaagagacc aaactattga agcgattgag tctatcgacg agcaccgcat
    21301 tatcggttta cagtggcatc cagagtttct ggttaatgaa gaagatggca atttagaatt
    21361 atttgagtat ttattgaatg aactgtaacg attggaacat ctggtcgttc tttcttttat
    21421 tttttcaaaa tttttagaat gtggcatttt acgcaaacgt ttgaattctg ataaaaattg
    21481 gagaaattcg acaaaaaaac ttgaaaaaaa cgaaggtaag cgttatgata gaaaagaaga
    21541 aatattggag gaagaacatg tcacatatta aatttgatta ttcaaaagtt ttagacaaat
    21601 ttgttgcacc acatgaagtg gaatacatgc aatcacaagt aacagcagca gatgaattga
    21661 tccgtaaagg aactggtgct ggtagcgact tcttgggatg gttggacctt cctgaaaaat
    21721 acgaccgcga agaatttgac cgcatcttga aagctgctga gcaaatcaag tcagacagcg
    21781 atgttttggt tgtgatcggt attggtggat cttaccttgg tgcaaaagca gcaatcgact
    21841 tcttgaatca ccattttgct aacttgcaaa caaaagaaga acgcaaagct ccacaaatcc
    21901 tttacgcagg aaactcaatc tcatctactt accttgctga cttggtagag tatgttgcag
    21961 acaaagactt ctcagtaaac gtaatttcta aatcaggtac aacaactgaa ccagcgattg
    22021 ctttccgtgt ctttaaagaa ctcttggtta agaaatacgg tcaagaagaa gctaacaaac
    22081 gtatctatgc aacaactgac cgccaaaagg gtgctgttaa ggttgaagca gacgctaacg
    22141 gttgggaaac atttgttgtt ccagatgata tcggtggacg cttctcagta ttgacagccg
    22201 ttggtttgct tccaatcgca gcatcaggag ctgacatcaa agctcttatg gaaggtgcga
    22261 atgcagctcg caaagactac acttcagaca aaatctctga aaacgaagct taccaatacg
    22321 cagccgttcg taacatcctt tatcgtaaag gctatgcaac tgagatcttg gtaaactatg
    22381 agccatcact tcaatacttc tcagaatggt ggaaacaatt ggctggtgaa tcagaaggaa
    22441 aagaccaaaa aggtatctac ccaacttcag ccaacttctc aactgacttg cactcacttg
    22501 gtcaatttat ccaagaagga actcgtatca tgtttgaaac agttgtccgt gttgacaaac
    22561 ctcgtaaaaa cgtgcttatt cctactttgg aagaagacct tgacggactt ggttaccttc
    22621 aaggaaaaga cgttgacttt gtaaacaaaa aagcaactga cggtgttctt cttgcccaca
    22681 cagatggtga tgtaccaaac atgtatgtga ctcttccaga gcaagacgct ttcactcttg
    22741 gttacactat atacttcttc gaattggcaa ttgccctttc aggttacttg aatgctatca
    22801 acccatttga ccaaccaggt gttgaagctt ataaacgtaa catgtttgcc cttcttggaa
    22861 aaccaggatt tgaagaattg agcaaagaac ttaacgcacg tctataatag aagaaaagag
    22921 tggtttgccc actcttttta ctctctttat ccatagaaat tggactcagc caagacttgt
    22981 gatataatat agaaagcaaa aaggcagacg cctagataat aggagaaact atgtcaaaag
    23041 atatccgcgt acgttacgca ccaagtccaa caggactact acacatcgga aatgctcgta
    23101 cagcattgtt taattacttg tatgcgcgcc atcatggtgg aacatttctc atccgtatcg
    23161 aagatactga ccgtaaacgc catgtcgagg atggtgaacg ttcacaactt gaaaaccttc
    23221 gctggttagg catggattgg gatgaaagtc cagaatcaca tgagaattat cgccagtctg
    23281 agcgtttaga cttgtatcaa aaatacattg accaactatt agctgaagga aaagcctata
    23341 aatcttacgt tacagaagaa gagttggcag ctgaacgcga acgccaagaa gtagctggcg
    23401 aaacaccacg ctacatcaat gaataccttg gtatgagtga agaagaaaaa gcagcttaca
    23461 tcgcagaacg tgaagcagca gggatcatcc caactgttcg tttggctgtc aatgagtcag
    23521 gtatctacaa gtggcatgat atggtcaaag gcgatatcga atttgaaggt ggcaatatcg
    23581 gtggtgactg ggttatccaa aagaaagacg gttacccaac ttacaacttt gccgttgtta
    23641 tcgatgacca cgatatgcaa atctctcatg ttatccgtgg agatgaccat attgctaata
    23701 caccaaaaca gcttatggtc tatgaagctc ttggttggga agctccagag ttcggtcaca
    23761 tgaccttgat tatcaactct gagactggta agaagttatc taaacgtgat actaatacac
    23821 ttcaatttat cgaagattac cgaaagaaag gttaccttcc agaagcagtc tttaacttta
    23881 ttgctcttct tggttggaac ccaggtggtg aagatgagat tttctctcgt gaagaactca
    23941 ttaaactttt tgatgaaaac cgcctcagca agtcaccagc agcctttgat cagaaaaaac
    24001 tagactggat gagcaatgat tatatcaaga atgcagacct tgaaaccatc tttgaaatgg
    24061 caaaaccatt cttagaggaa gcaggccgtt tgactgacaa ggctgaaaaa ttagttgagc
    24121 tctataaacc acaaatgaaa tcagtagatg agattatccc attgacagat cttttcttct
    24181 cagatttccc agaattgaca gaagcagagc gcgaagtcat gacgggtgaa acagttccaa
    24241 cagttcttga agcattcaaa gcaaaacttg aagcgatgac agatgatgaa tttgtgacag
    24301 aaaatatctt cccacaaatt aaagcagtcc aaaaagaaac aggtattaaa gggaaaaatc
    24361 ttttcatgcc tattcgtatc gcagtttcag gcgaaatgca tgggccagaa ttaccagata
    24421 caattttctt gcttggacgt gaaaaatcaa ttcagcatat cgaaaacatg ctaaaagaaa
    24481 tctctaaata aagaggatac aataatggac atctgggaaa agatgtacga agaagcacag
    24541 aaactataca atccacatga agtatcagac tttgtttatg ccaatcatgt tgtagctgca
    24601 gtagaagcag gagatggaca aatatttaca ggattctgta tggagggaac ctgtggtgtt
    24661 ttccatctct gcgcagaacg ggcggccctc ttcaatatgt accaattttc aggacaaact
    24721 aaggttaaga aagtattagc ctttcgagac aaaccacctt atggtggaag ttcagccatg
    24781 ccttgcggtg cttgtagaga attcctttta gagtttaatg ctgaaaataa agatgcagaa
    24841 ttcatgatgg actataatat aagaaaaaca gttaaagtcg cagaactaat cccttattgg
    24901 tggggagaag aacgtgcttc taagtttaat gagcgataga agagtcagta taattctggc
    24961 tttttttact ataagttgaa aaaata
//
LOCUS       DAVLDI010000032        24637 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLDI010000032 DAVLDI010000000
VERSION     DAVLDI010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24637
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.032"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            362..1525
                     /locus_tag="VXD01_001319"
     CDS             362..1525
                     /locus_tag="VXD01_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV0601709.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1522..2199
                     /locus_tag="VXD01_001320"
     CDS             1522..2199
                     /locus_tag="VXD01_001320"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV0601710.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2189..3043
                     /locus_tag="VXD01_001321"
     CDS             2189..3043
                     /locus_tag="VXD01_001321"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV0601711.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3062..4129
                     /locus_tag="VXD01_001322"
     CDS             3062..4129
                     /locus_tag="VXD01_001322"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV0601712.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            4139..5305
                     /gene="aroC"
                     /locus_tag="VXD01_001323"
     CDS             4139..5305
                     /gene="aroC"
                     /locus_tag="VXD01_001323"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV0601713.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5315..6418
                     /locus_tag="VXD01_001324"
     CDS             5315..6418
                     /locus_tag="VXD01_001324"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV0601714.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            6429..6767
                     /locus_tag="VXD01_001325"
     CDS             6429..6767
                     /locus_tag="VXD01_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV0601715.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6859..8142
                     /gene="aroA"
                     /locus_tag="VXD01_001326"
     CDS             6859..8142
                     /gene="aroA"
                     /locus_tag="VXD01_001326"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV0601716.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGASVIIEKECTRNHTEDMLKQFGGHLSVDSKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8135..8611
                     /locus_tag="VXD01_001327"
     CDS             8135..8611
                     /locus_tag="VXD01_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV0601717.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIVADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8608..9456
                     /gene="pheA"
                     /locus_tag="VXD01_001328"
     CDS             8608..9456
                     /gene="pheA"
                     /locus_tag="VXD01_001328"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0601718.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAENPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9453..10727
                     /gene="psr"
                     /locus_tag="VXD01_001329"
     CDS             9453..10727
                     /gene="psr"
                     /locus_tag="VXD01_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV0601719.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11006..11851
                     /locus_tag="VXD01_001330"
     CDS             11006..11851
                     /locus_tag="VXD01_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0601720.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11841..12944
                     /locus_tag="VXD01_001331"
     CDS             11841..12944
                     /locus_tag="VXD01_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV0601721.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            12946..13932
                     /locus_tag="VXD01_001332"
     CDS             12946..13932
                     /locus_tag="VXD01_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0601722.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            13948..15381
                     /locus_tag="VXD01_001333"
     CDS             13948..15381
                     /locus_tag="VXD01_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV0601723.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15410..16444
                     /locus_tag="VXD01_001334"
     CDS             15410..16444
                     /locus_tag="VXD01_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV0601724.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16644..17381
                     /gene="mecA"
                     /locus_tag="VXD01_001335"
     CDS             16644..17381
                     /gene="mecA"
                     /locus_tag="VXD01_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV0601725.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17532..18818
                     /locus_tag="VXD01_001336"
     CDS             17532..18818
                     /locus_tag="VXD01_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV0601726.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18820..19689
                     /locus_tag="VXD01_001337"
     CDS             18820..19689
                     /locus_tag="VXD01_001337"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV0601727.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            19765..19842
                     /locus_tag="VXD01_001338"
                     /pseudo
     CDS             19765..19842
                     /locus_tag="VXD01_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            19984..20922
                     /gene="msrB"
                     /locus_tag="VXD01_001339"
     CDS             19984..20922
                     /gene="msrB"
                     /locus_tag="VXD01_001339"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV0601728.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            20980..22704
                     /locus_tag="VXD01_001340"
     CDS             20980..22704
                     /locus_tag="VXD01_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601729.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VLVAILTIVIVGLSRLVNPFYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            22706..24457
                     /locus_tag="VXD01_001341"
     CDS             22706..24457
                     /locus_tag="VXD01_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601730.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
BASE COUNT         7225 a         4590 c         5580 g         7242 t
ORIGIN      
        1 tttgtaacaa aaggcttctc tataaaatca aattttccag atacctattg aagcagattt
       61 atttcttcat ctttcttcta ctacctttgt cactaaattt gacagacaca tattgctgat
      121 tcaacctctc tacctataat ctcacagtta acctgaggct agtttcatag tttgttattt
      181 gattttcgtt gataaaaaga aatgctcctc caagacggaa gagcattttt tattgtgatt
      241 cttacacatt tacttcctag ttttgcagga agtctagtat accatttttt aaaagaagag
      301 taaaaaagca agggtagttt cttttttgag aattgtctaa aagtttgata taatggtagt
      361 tatgaataga ataagagtca gcaaaagggt tgaaaagaag cttgctaagg ggctagtttt
      421 actagaagcc agtgatcttg agaatgtcaa tcttaaggat caggaagtag aggtgcaggg
      481 tcaggaagga aactttcttg ggactgccta cctttctcag caaaacaagg gcttgggctg
      541 gtttgtcagc aaagacaagg tggccttcaa tcaaactttc tttgaaacgt tgtttagaaa
      601 agccaaagaa aagagaaacg cctactatca agatgatttg acaactgcct ttcgtctctt
      661 taatcaagag ggagatggct ttgggggtct gacagtggac ctttatggcg actacgccgt
      721 cttttcttgg tataactctt atgtttatca gattcgtcag actatatcag aagcctttag
      781 acaggttttc cctgaggttt taggggctta tgagaaaatc cgctttaagg gttttgacta
      841 tgaatctgcc catgtttatg gtcaagaagc acctgacttt ttcactgttt tagaaaatgg
      901 tgtcctgtat caagtcttta tgaatgatgg cttgatgaca ggaattttcc tagaccagca
      961 tgaggttcgc ggtagtttag ttgacggctt ggctatgggt aaatccttgc tcaatatgtt
     1021 ttcctacaca gcggcttttt cagtagctgc ggccatggga ggagctagcc agacaacttc
     1081 tgttgatcta gccaaacgtt cacgagaatt gtctcaagcg cattttcagg caaatgggct
     1141 cagcacagac gagcatcgtt ttatagtcat ggatgtcttt gagtatttca aatatgccaa
     1201 acgcaaagac ttgacctacg atgtgattgt cctagatccg cctagctttg ctcggaataa
     1261 aaaacaaact ttctctgtgg ccaaggatta tcacaagttg atttcccaga gtcttgagat
     1321 tttaaatccg ggagggatta tcattgccag taccaatgct gccaatgttt cccgtcagaa
     1381 atttacagaa caaattgata aaggttttgc aggaagaagt taccagattt taaacaaata
     1441 tggtcttcca gcagattttg cctataataa aaaagatgaa agtagtaatt acctcaaggt
     1501 gattagtatg aaggttagta aatgaaatta atcgtttcag taatgccaag aagtttagag
     1561 gaggctcagg ctctggatgc cacgaggtac ctggatgccg acatcattga atggcgtgcc
     1621 gactatctgc ctaaagaagc gattttgcag gtagctccag ccatttttga aaaattcgca
     1681 ggccgtgagt tggttttcac gctacgaact cgctccgaag gtggagaaat cgacctttct
     1741 ccagaagagt atatccatct aatcaaggaa gttgcgcaat tctatcaacc agactatatt
     1801 gattttgagt actatagcta caaggatgtt tttgaggaaa tgctggactt cccaaatctt
     1861 gttttgagtt accataattt ccaagaaaca cctgagaaca tgatggaaat cttgtcagag
     1921 ttgacgatcc taaatccaaa acttgttaag gttgcggtga tggctcacac ggagcaggat
     1981 gtcttagact tgatgaacta tacacgaggc tttaaaaccc tcaatcctga acaggaatat
     2041 gtgaccattt ctatgggtaa ggtgggcaag gtctctcgta tcactgcgga tgtgactggt
     2101 tcgagttggt cttttgccag tctggatgag gttagtgccc ctgggcagat ttctctagct
     2161 agcatgaaaa aaatcaggga gattttggat gaagcttgat ggctatacac gtttagctgc
     2221 agttgttgcc aatcctatta agcattctat ttctcccttc atccacaata gagcctttga
     2281 ggcgacagct accaacggtg cttatgtggc ttgggagatt gaagcgagtg acttggtaga
     2341 aacagtggcc aatattcgtc gctaccagat gtttggcatc aatctgtcca tgccctataa
     2401 ggagcaggtg attccttatt tggataagct gagcgatgaa gcgcgcttga ttggtgcggt
     2461 taatacggtt gtcaatgaga atggcaattt aattggatat aatacagatg gcaagggatt
     2521 ttttaagtgc ttgccttctt ttacaatttc aggtaaaaag atgaccctgc tgggtgcagg
     2581 tggtgcggct aaatcaatct tggcacaggc tattttggat ggcgtcagtc agatttcggt
     2641 ctttgttcgt tccgtttcta tggaaaaaac aagaccttac ctagacaagt tacaggagca
     2701 gacaggcttt aaagtggatt tgtgtgcttt agaatatgtt tctgaactgc aagcaaggat
     2761 tgccgagtcg gatttgctag ttaatgccac cagtgtgggc atggatggcc aatcctctcc
     2821 tgttcctgaa aacatagtct taccagaaac tcttttagtt gcagatatca tataccaacc
     2881 ctttgaaaca ccgtttttga aatgggctag aagtcagggc aatccagcag tcaatggtct
     2941 gggaatgttg ctctatcaag ctgcagaagc ttttcaactg tggacaggca aggaaatgcc
     3001 gacagaagag atttggcagt ctttaacaga aaaataccaa taaagaaagg gagactctcc
     3061 tatgaaaatc agaatcgata ttcctcatca tccttatgat attcagattg aaaaaggttg
     3121 tatggcccag gctggtcagt ggttgcgaga actctggcaa ccgcaaaagg tagtcattgt
     3181 gacagataac catgtagcct ctctctatgc agagaaggtc aagctcagcc tagaagatgc
     3241 tggttttcag gtagctgttt ttgatttctt agaaggtgaa gaaagaaaga atttaactac
     3301 tgttcagaaa gtctatgaat ttctagtcaa gcaaggtctg actcgtagcg atggaatcgt
     3361 tgctcttggt ggtggcgttg ttggggacct ggctggcttt gtagcctcta cctatatgcg
     3421 gggtattcac tttgttcaga ttccgactag tttgacagct caggttgatt cttctatcgg
     3481 tggaaagaca ggcgttaaca caccatttgc taaaaatatg gtggggacct ttgcccaacc
     3541 agatggggtt ctgattgatc cacttgttct tgaaaccctc ggaaaaagag agttgattga
     3601 agggatgggt gaagttatca agtatggctt gattgaggat ccagaactgt gggctctctt
     3661 gacgggactg aatggttctg ttgagagtat tttggaacat gcagagacct tgattgaaca
     3721 ttcttgtcag gtgaagcgca agatggtggt tgaagatgag ttggacaatg gtattcgtct
     3781 ttacctcaat tttggccaca ctattggcca tgccatcgaa gcgactgccg gttatggcaa
     3841 ggtcatgcat ggagaggctg ttgccatggg aatggtacag atttccaagg ttgctgagga
     3901 aaaaggcctc atgccagctg gcattaccca atctatcaca gagatgtgtc agaaattcgg
     3961 cttgcctgtt gactatgaaa attggaaagt tgacaagctt tatcaggctc ttactcatga
     4021 caagaaagcg cgtggtaaca ccttgaaatt ggtcttggtg ccagagcttg gttcagcgac
     4081 cattcaccca gtttctctgg aagagatgaa agactacttg gtaaaataag gagagtgtat
     4141 gagatattta actgcaggag aatcacacgg cccccgtcta acagctatta ttgagggaat
     4201 tccagctgga cttccattga cagctgagga tatcaatgag gatcttagac gccgtcaggg
     4261 tggctacggt cgtggtggtc gtatgaagat tgagagtgac caggttgtct ttacttcggg
     4321 tgttcgccac gggaagacga caggggcgcc tattactatg gatgtcatca ataaggacca
     4381 ccagaaatgg ctggacatca tgtctgcgga ggacattgaa gaccgcctta aaagcaagcg
     4441 gaaaattact catcctcgcc caggtcatgc cgatttggtt ggggggatta agtaccgttt
     4501 tgatgatttg cgaaattctt tggagcgttc atcagctcgt gaaaccacca tgcgggtggc
     4561 agttggtgca gtagccaaac gcctcttggc tgagctggat atggagattg ccaaccatgt
     4621 cgtggtcttt ggtggtaagg aaatagatgt tcctgaaaat ctgacagtcg ctgaaattaa
     4681 gcaaagagct gcccagtctg aagtttctat tgtcaaccaa gaacgagaac aggaaatcaa
     4741 ggactatatt gaccaaatca aacgtgatgg tgataccatc ggtggggttg tggagacagt
     4801 cgtcggagga gttccagttg gtcttggttc ctatgtccaa tgggatagaa aattggatgc
     4861 aagattggct caagctgttg tctctatcaa tgcctttaaa ggggtggaat ttggtcttgg
     4921 ctttgaggct ggttatcgta aaggcagcca agttatggat gaaattctct ggtctaaaga
     4981 agacggttat actcgccgta ccaataatct aggtggtttt gaaggtggta tgactaatgg
     5041 gcaacccatc gttgttcgtg gggtcatgaa acccattcct actctttata aacctcttat
     5101 gagtgtggat atcgaaaccc acgaacctta caaggcaacc gtggagagaa gtgatccgac
     5161 tgctcttcca gctgcaggaa tggtcatgga agcagttgta gcaacggttc tggcgcaaga
     5221 aatcctcgaa aaattctcat cagataatct tgaggaacta aaagaagcgg tagccaaaca
     5281 ccgagactat acaaagaact attaaggagt tcctatggca aaaacaatct atatcgcagg
     5341 tcttgggttg attggagcct ctatggcact tggtatcaaa cgcgatcatc cagattatga
     5401 aattttaggt tataatcgta gtcaagcttc gagagatatc gccttgaaag aaggtatgat
     5461 tgaccgtgca acggatgatt ttgctagttt tgctcctttg gcagatgtca ttatcctcag
     5521 cttgccaatc aaacaaacta ttgctttcat taaggagttg gccaatttgg atttgcgaga
     5581 aggcgttatt atttcagatg ctggttcgac caagtcaacc attgtggatg cggcggagca
     5641 gtatttggct ggcaagtctg ttcgctttgt cggggcccat cccatggctg gtagtcacaa
     5701 gacaggggct gcttcggcag atgtcaatct ttttgaaaat gcctattata tctttacacc
     5761 ttcaagcctg acaagtcagg acacgcttaa ggaaatgaag gatctgcttt caggtcttca
     5821 tgctcgtttt atcgagattg atgccaagga gcatgatcgt gtcacttctc agattagcca
     5881 ttttcctcat attttggctt ctagtctcat ggagcagact gcggtctatg ctcaagagca
     5941 tgagatggca aggcgctttg cggcaggtgg ttttcgagat atgacccgaa ttgcggaaag
     6001 cgagccagga atgtggacct ccattctctt gtccaatagc gagaccattc tggatagaat
     6061 tgaggatttc aaggaacgtt tggaagtgat tggtcaggcc attagtaagg gagatgaaga
     6121 gcaaatttgg aactttttta accaagcgcg tgaacaacgc cagaccatgg aaatccataa
     6181 gcgtggtggt gtggatagct cttacgacct ctatgttgac gttcctgatg aagaagatgt
     6241 catcctgcgg attttggaac tgctacgtgg aacttccttg gttaacatcc acatcaacga
     6301 ggaaaatcgt gaggatattc acggaatcct acaaatttca tttaaaaatg ctcaagactt
     6361 ggaaagagct gagcatctca taacagaaaa taccgactat acagtcgtca tcaaataagg
     6421 agaagaacat gtcaaatatt tacgatagtg caaacgaact cagtcgcggt ctacgcggat
     6481 taccagaata caaggctgtt aaagcagcta aagatgcgat tgcagcagat gctgaggcaa
     6541 gcaaaatctt tacagaatat cttgcctttc aagaggaaat tcaaaaacta gcacagacag
     6601 gtcaaatgcc agatgcgtcc ttccaagcta agatggaagg ctttggtaaa cagattcaag
     6661 gaaatagcct cttgtcagaa ttctttacca agcaacaaca attggccatt tacctttctg
     6721 acattgaaaa aattgttttt gaaccagttt cagaattgct gaaataagaa aagaacgatc
     6781 ctaaagtcag gaatttttaa ggaatttctg actttttatg ataaaatagg taaaagtatt
     6841 gcaagtatga ggtccagtat gaaactaaaa acaaacattc gccatttaca tggtagtatc
     6901 cgcgtcccag gtgacaagtc tatcagccac cgttccatta tctttggaag tttggctgag
     6961 ggtgagacca aggtttatga tattctacga ggtgaagacg ttctttcgac catgcaggtt
     7021 tttcgtgacc ttggtgttga aattgaggat aaagatgggg ttattaccat tcaaggtgta
     7081 ggcatggctg gcttaaaagc gccgcaaaat gcccttaata tgggaaattc tggcacctcg
     7141 attcgcctga tttcaggtgt ccttgctggt gcagatttcg aagtagagat gtttggagat
     7201 gatagtcttt ccaaacgtcc tatggaccgt gtgacccttc cactgaaaaa aatgggcgtc
     7261 agcatttcag ggcaaactga acgagacttg cctccccttc gcttaaaagg gacgaaaaac
     7321 ctaagaccta ttcattatga gttgccaatt gcctctgccc aagtcaagtc agccttgatg
     7381 tttgcagcct tacaagctaa gggggcgtca gttattatcg aaaaagagtg cacccgtaat
     7441 catactgaag atatgttgaa acaatttggt ggtcatttaa gtgtggacag taagaaaatc
     7501 acagtccaag ggccacaaaa attgacagga cagaaggtgg tcgtaccagg agatatttcc
     7561 agtgcagcct tttggttagt cgcaggtttg attgttccaa attctcgtct agtgctgcag
     7621 aatgtgggga tcaacgaaac tcgcaccggt attattgatg tcattcgtgc catgggtgga
     7681 aaattggaaa taactgaaat cgatccagtc gctaaatctt ctaccttgac tgttgagtct
     7741 tctgacttga aaggaacaga gattggtggc gctttgattc cacgattgat tgatgaattg
     7801 cccattattg ccctgcttgc gactcaagcc caaggtgtaa cagttatcaa ggatgctgag
     7861 gagctcaagg tcaaggaaac agaccgtatt caggttgtgg cagacgcctt aaatagtatg
     7921 ggagcagata ttactcctac ggcagatggg atgattatca aagggaaatc agctcttcac
     7981 ggtgctagag tcaatacgtt tggtgaccac cgtatcggca tgatgacagc tatcgcagcc
     8041 ctcttggttg cagatggaga ggtggagctt gaccgtgcag aagccatcaa taccagctat
     8101 cctagtttct ttgatgattt ggagagcttg attcatggct aaggtgttat tagggtttat
     8161 gggggctgga aaatcgacta ttgcaagagg cttggaccct aattaccttg atatggatgc
     8221 tctgattgag aagcgcctag gtatgtccat tgcgaatttt ttcgctgaaa agggagaagc
     8281 agcctttcgt caggtagaat cagaagtcct agctgattta ctacaaacag accaagtcgt
     8341 gtcaactgga ggaggagtgg ttatttctca gagaaatcgt gacttactca agactaatac
     8401 agataacatc tacctgaaag cagattttga aaccctctac ctacgtatcg tagctgataa
     8461 ggacaatcag cgaccgcttt ttctaaataa tagcaaggaa gaactagtag ctatttttca
     8521 agaaagacag gcttggtatg aggaagtggc tagtcgggtt ttggatgtga ccaagctaag
     8581 cccagaggaa attatagagg aactaagatg aaaattgctt atctaggtcc caagggatca
     8641 ttttcacacc acgttgtgca gacagctttt cctcatgagg aattgcaggc ttttgccaac
     8701 attacagatg tcatcaaggc ttatgagcaa ggattagtga actattctgt ggtgccagtt
     8761 gaaaattcta ttgagggtag tgttcatgaa accttggact atctttttca tcaggctcac
     8821 atccaagcag tagcagaaat cgttcagcct attcatcagc agttgatggt ggttccaggc
     8881 catactaaga ttgaaaagat tttttcacat ccacaggcct tggctcaagg aaagaaattc
     8941 atcgatgaac aatatccaga ggctcaaatc gaggtaacag ctagtacagc ttatgcggcc
     9001 cgttttattt ccgaacatcc agaccagccc tttgcagcag ttgcacctag aagttctgct
     9061 gaagaatatg gattggaact gattgccgag gatattcagg aaatggaagc caatttcaca
     9121 cgtttctggg ttctaggagc tgaaaatcct agtattccct tgcaagcaca aactgaaaag
     9181 atgagtttgg ccttgacatt acctgacaac cttccaggtg cactttataa ggccctgtcg
     9241 acctttgctt ggcgaggaat tgacttgaca aaaattgaaa gtcgtccact caagacagca
     9301 ctgggtgaat actttttcat tatcgatgtg gattataccg ataaggactt ggtccacttt
     9361 gcccaaaaag aattagaagc gattggaatc cagtataaaa ttctgggtgc ctatcctatt
     9421 tatccaatat cagaccatgg aaaggagaga agatgagtaa agaaaatccc ttaagtcatc
     9481 atgagcagtt gcgttatgat tatttgctaa aaaatattca ctatctcaat gagagagaaa
     9541 aaaatgagtt tgcctatttg caagaaaagc taactcttgc taggggaaat agtagctcta
     9601 gcttggaaca agaaagagaa gagcaggttg acttaccaag ctatgcgaac cggagtcgct
     9661 cacaatccaa atcacaagca ctctcttccc ctccaaaaaa gaaaagacgg aagctccgtc
     9721 ttaaacgaat ttttatggtg attttttcac ttttggtctg tgtggctttg gccatggtat
     9781 tcatgttttt gcgtggttac caagatgcta gcgcaaagaa aactgctgat gctcgggcag
     9841 ctcaagtaga agtctttaat ggtcaggaca ctagagatgg agttaatatt ttaatcatgg
     9901 gtactgatgg tcgaatcggc cagaacagtg ttgagacacg aactgactct attatggtat
     9961 taaatgtcgg gggctcagat aagaaaatga agctagtcag tttcatgcgt gataatttgg
    10021 tctatataga tggttatagt caagtgatta acggtagaaa acagacagat aacaagttaa
    10081 acgtagccta cgagttagga gaacaagagg ggcaaaaagg ggcagaaatg gttcgccaag
    10141 tcttgaaaga taattttgac ttggacatta agtactacgc cttggttgat ttccaggcct
    10201 ttgccacagc gattgacacg cttttccctg atggggtgac gattgatgct caattttcaa
    10261 cattgaatgg gcgtccccta acagaagcta cagtcggaga tgatttatac gctaccgaga
    10321 ctgagtctcc aacccaaacc attaaagtcg gaaaacagca gatgaatggc tcgaccctgc
    10381 tcaattatgc tcgtttccgt gatgatgatg aggcagatta cggccgtaca aaaagacagc
    10441 aacaagtttt aacagcaatt ttagagcaaa ttaaagatcc cactaaactt ttcactggtt
    10501 ctgaagctct tggaaaggtt tttgctatga cctcaaccaa cgtaccctat actttcctcc
    10561 taacaaacgg tttatctgtt ttggatggag caaaaaatgg tattgaaaaa ttgacgattc
    10621 cagaactggg tgactgggta gatgcctatg atgtttatgg aggcttgggc ttgctggttg
    10681 atcaaaacaa atatcaaacc aagctcgctc aaatgggctt gagataagat aatactcaat
    10741 gaaaatcaaa gtgcaaacta ggaagctagc cgcaggctgc taaaaacaca gttttgaggt
    10801 tgtagataag actgacgaag tcagttacct atacctacgg caaggtgaag ctgacgtggt
    10861 ttgaagagat tttcgaagag tataagacag aaaaatcaaa gtttgatagc tatttggata
    10921 gcagtcaggc tttgattttt tacagtctgc aatagatttt caccccttgt ttgtggtata
    10981 atgaaacgat acgatagaaa gaataatgaa caatatgact gatttaaaag caattcaggc
    11041 tcgtagtctg gagatggctg aatattttgt ggccttttgt aaagaacatg atttgctctg
    11101 ttatctctgt ggcggaggcg ctattggtgc ccttcgaaac aagggattta ttccttggga
    11161 cgacgaccta gactttttta tgcctcgtaa agattatgag aaattagcag aattatggcc
    11221 tcgttatgca gatgaacgtt atttcttgtc aaagagtcac aaggattttg ttgatcgtaa
    11281 tctttttatt accattcgtg acaaggaaac cacctgtatc aagccttatc agcaggattt
    11341 ggatttgcca catggtctgg ccttggatgt tttgcctttg gattattatc cgaaaaatcc
    11401 agctgagcgg aaaaaacagg ttcgttgggc cttgatttat tcactctttt gtgcgcaaac
    11461 tattccagaa aagcatggtg ctctcatgaa atggggaagt cgcattttac tgggtttgac
    11521 tccaaaatct ctctgttatc gcatctggaa aaaagctgag aaagaaatga ctaagtatga
    11581 tttggctgat tgtgatggca ttacagaatt atgctcaggt cctggctaca tgagaaacaa
    11641 gtacccaatc acatcttttg aagacaatct tttcttgcca tttgaaggaa cagagatgcc
    11701 tattccaatc ggctatgatg tctatctcag aactgctttt ggggattata tgacgcctcc
    11761 accagcagac aagcaggtac cgcatcatga tgctgtcatc gctgatatgg ataagtctta
    11821 tacagaatac aagggagaat atggtggcta agaaaaaaat cttatttttt atgtggtctt
    11881 tttctcttgg aggtggtgca gagaagattc tatcaaccat tgtttcaaat ctggatccag
    11941 aaaagtatga tattgatatt cttgaaatgg agcactttga caagggatat gaatctgttc
    12001 caaagcatgt acgcatttta aaatcccttc aagattatcg ccaaaccaga tggttacgag
    12061 cttttttgtg gagaatgaga atttattttc caagactggc tcgtcgtttg cttgtaaaag
    12121 atgattatga tgttgaagtt tcttttacca ttatgaatcc accactgttg ttctctaaaa
    12181 gaagagaagt caagaagata tcttggattc atggaagtat tgaagaactt cttaaggata
    12241 gctctaaaag agaatcacat agaagccagt tggatgctgc gaatacaatt gtagggattt
    12301 caaaaaagac cagcaattct atcaaggaag tttatccaga ttatacttct aaattacaga
    12361 caatctacaa tggatatgat tttcagacta ttctagaaaa atctcaagag aagatcgata
    12421 tcgagattgc tcctcaaagt atctgtacta tcggacggat tgaggaaaat aagggttctg
    12481 accgtgtagt ggaagtgata cgattattac accaagaggg aaaaaactat catctctatt
    12541 ttatcggggc tggtgatatg gaagaggaac tgaaaaaacg agtcaaagag tatgggattg
    12601 aggactatgt acatttcctt ggttatcaaa aaaatcctta tcagtatcta tctcagacga
    12661 aagttctttt gtctatgtct aaacaagaag gttttcctgg agtgtatgtg gaggccttga
    12721 gtctgggact cccttttatc tctacggacg ttggaggggc tgaggaatta tcccaagaag
    12781 gacgatttgg acaaatcatt gagagcaatc aagaggcagc tcaggcgatt actaattaca
    12841 tgacttctgc ctcaaacttt gatgtcgatg aggctagcca attcattcaa caatttacaa
    12901 ttacaaaaca aatcgaacaa gtagaaaaac tattagagga gtagcatgga aactgcatta
    12961 attagtgtga ttgtgccagt ctataatgtg gcgcagtacc tagaaaaatc gatagcttcc
    13021 attcagaagc agacctatca aaatctggaa attattcttg ttgatgatgg tgcaacagat
    13081 gaaagtggtc gcttgtgtga ttcaatcgct gaacaagatg acagggtgtc agtgcttcat
    13141 aaaaagaacg aaggattgtc gcaagcacga aatgatggga tgaagcaggc tcacggggat
    13201 tatctgattt ttattgactc agatgattat atccatccag aaatgattca gagcttatat
    13261 gagcaattag ttcaagaaga tgcggatgtt tcgagctgtg gtgtcatgaa tgtctatgct
    13321 aatgatgaaa gcccacagtc agccaatcag gatgactatt ttgtctgtga ttctcaaaca
    13381 tttctaaagg aatacctcat aggtgaaaaa atacctggga cgatttgcaa taagctaatc
    13441 aagagacaga ttgcaactga cctatccttt cctaaggggt tgatttacga agatgcctat
    13501 taccattttg atttaatcaa gttggccaag aagtatgtgg ttaatactaa accctattat
    13561 tactatttcc atagagggga tagtattacg accaaaccct atgcagagaa ggatttagcc
    13621 tatattgata tctaccaaaa gttttataat gaagttgtga aaaactatcc tgacttgaaa
    13681 gaggtcgctt ttttcagatt ggcctatgcc cacttcttta ttctggataa gatgttgcta
    13741 gatgatcagt ataaacagtt tgaagcctat tctcagattc atcgtttttt aaaaggccat
    13801 gcctttgcta tttctaggaa tccaattttc cgtaagggga gaagaattag tgctttggcc
    13861 ctattcataa atatttcctt atatcgattc ttattactga aaaatattga aaaatctaaa
    13921 aaattacatt agaacggggg tgaccaagtg attgatggga aacgattatt atttagtttg
    13981 accatagtca gttatgcctt gacgctagta agtggaattg tgtatctgtt taataataat
    14041 aatgttagct tactttctac tttattgttc ttgttggtta gtagcttgat tgcttgttgg
    14101 aatgatatca agtattactt aatccatttt attttctatt taaccatttt tgtatttctg
    14161 gtatcaagac cgaccattga ttattttagg gatggtgctt tggataccta tcatccaata
    14221 gcctatcgtt ttgcctttat agttgtcatg gtttcgattc tgggcttgac cacaggaggc
    14281 attctggctc gttacttcat agctaggaag aaaataaaag tagcaaatat aggaaattct
    14341 ctaaaagagg tttatatcaa gcggttacgc tttgtatcac taggagtttt tcttctaacc
    14401 tatcctttct atttcattcg gttatttgaa cggctcttgt atcgtttgca gacttcctac
    14461 tatgcctact atgcaaattt tgaaagtaaa ctgccttatt ttacctacat tttgtctacc
    14521 tttacggtct atgcaatgtg tatgtatctg gcaaccaagc caaagaaatt gcaggccaca
    14581 gcagtgcttg tctcctttat tgcagctaat actattcatt tggcaattgg gacacgaaat
    14641 ccctttattt taagtatttt atttgctttt gtttattact ttatgcggga gcaaactgaa
    14701 aaaggaaaat ggattgggtt taaagaaaag ttagcgattt ttgtaggttc tcctattctc
    14761 atgttagcga tgggagtact taattatgta cgggataatg tccaagtttc ccatacaggt
    14821 ttctgggata tcttacttga ctttatctat aaacaaggaa ctagttttgg tgttctggct
    14881 cgaggttttc tatttaacag tagcctccct taccgagatt tccgtaattt tacttttggt
    14941 cctgttcttg attattttgc aagggggagt ttgggagcca ttttcggagg aaaagccttt
    15001 gaacatacaa ccaatagtgt ggaactagct attgatagta atagttatgc ccacaatcta
    15061 tcctatcttg tcttgaacaa ggaatacttg aaagggcatg gtatcggaag tagttatatc
    15121 atggagttgt ataccgacta tggtatgatt ggagtctttc tgcttagttt cttactcggc
    15181 gtattattta tagccatgct gcaagtagcc tatcgctcaa ggacaatcct atttgcttta
    15241 tccctactca tcttgaataa tctattcttt atgccaagaa gcagcttttc agaaagtttc
    15301 ttcaatttat ttacaatgca attctgggga attgttcttg tgattatatt tgtagcaaaa
    15361 atgcttacaa aggaaaacta gtatctacta aacaaaggag aaaaaaatca tgtttgaaca
    15421 ttattcagta gctgatttgt ttgcaaatct ttataaaaag cgaaaagcaa atattttagc
    15481 tctcatcgct ttatttgctc tcattgctgt accatttaca attaaagcag ttaggaataa
    15541 aaacactgtc aaagatacaa caagttattc aacttatctt atctataaaa tcactcctcc
    15601 aaaagagtcg gccaaaacga ttttgaatca tcaaattggt ggttatagtg atttttatgg
    15661 gaaattgatt gatggtaatt tgaatggagc ttatcttttc aatgatgtag aacccagtga
    15721 gttgaaaaaa attgccagtg aattagacac gacagaaaca accttgaaaa attcaacgaa
    15781 tgactattgg tggaaaaaat tgaccgtcta ctatatgatt gacgatgcag gggttggtgt
    15841 gaaaattttg acatcaagta aagatgccaa tgacttgtta gagaaaaaaa ttgatgggtt
    15901 gattgagaaa tttaaacatg cctatgcaaa tgtgaaaatt gaaaaactgg aaaccatcaa
    15961 ctctaaagaa ttgaacgcaa atggtgaaac agcgcttggc ttaaatgtga aaaatctgat
    16021 tcttcgttta gttgttattg gagtggtttg tgtgattttg gttgtgatgg gaaatgtgtt
    16081 agtttatctc tttaatccaa caatcaatag agtaggtgat ttttctcagt atcaaattga
    16141 ttttgtaaca gagattacaa caattgctaa cctagcagat gttttgtcat acaaaaatac
    16201 tggacaggaa ttgaccatcg ttagctcaaa taaagctatc ctagataaat tgaaacagag
    16261 tcaagaagct ttaaaaggaa tgcattttgt agatttacag gatgtatcat ctcttttgga
    16321 aagagataca gtccttcttg ttgaagagta cggagtgact cgttataaga aatttgagca
    16381 aagtcttcaa attctcagaa acttaaatcg ttctatcctt ggtgtagcaa cctttaaatt
    16441 ataagtattc tgatgtataa ggtcttcaaa atcggctaag agctgatttt gaaggctttt
    16501 tctatctgtc tgcagaaatt ttcttttgga gtctcctata gaaagaccct agggaaaatc
    16561 tatccgtata gaggagcctt cttttgataa aatcgtaaaa atctagtata atagatagaa
    16621 ctgaaagtat gaggttacta gcaatgaaaa tgaaacaaat tagtgataca actttaaaaa
    16681 tcacgatgtc tttagaggat ttgatggatc gtggaatgga gattgctgac tttctcgttc
    16741 ctcaagaaaa aacagaagag ttcttttatg ctatcttgga tgaactagag atgcctgata
    16801 gctttctgga tacaggcatg ttgagcttcc gtgtgactcc aaaacctgat aaggtagatg
    16861 tctttgtgac caagtcaaag attgaccaaa atctagattt tgaagactta tcggatttgc
    16921 cagatatgga agaattggct caaatgtctc cagatgaatt tatcaaaacc ctggaaaaaa
    16981 gcatcgcaga caaaaccaag gatgatatcg aagccattca atctcttgag caagttgaag
    17041 ccaaggaaga agagcaagag caggctgaac aagaagctga gagtaagaaa gaaccttaca
    17101 tctactacat cctttctttt gctaagttgg ctgacttggt agtttttgcc aagacagtga
    17161 cttttgaaat ggaaacttct gaactctaca aaatgaacga gcgctattat ttgaccattt
    17221 tagtggatat tgaaaatcat ccaagcccat atccagcttg gctgttggcc cgtatgcgcg
    17281 agtttgcaga cgatagtgat atcagtcgct cagtcttaca agagtatggt caagtcttga
    17341 tgagtcacga tgcagtgctc aatctgcaaa aaatcggcta atcctttctg gaaagctatt
    17401 ttcagatttt aagaagagcg aatcgtctga ttcgtttttt ctttttatac tgaaatagtg
    17461 atttactata ataggaattt tcacaaaatt ctgttataat ggctatatta gaaaatttcg
    17521 aggagataaa gatgacagtt aaaattgctt tactaggatt tggtaccgtt gcaagtggtg
    17581 tgcctttcct cctaaaggaa aatggaggaa aaatcaatca atcagcacat tcagatatca
    17641 aagttgctaa ggtattggtc aaggatgaag atgaaaaaaa tcgcttgctt gcagcaggga
    17701 atgactttaa ctttgtaacc aatgtggatg atattttatc agaccaggat attactatcg
    17761 tagtggaatt gatggggcgt attgagcctg ctaaaacctt tatcactcgt gccttggaag
    17821 ctggaaaaca cgttgttact gctaacaagg accttttagc tgtccatggc gcagaattgc
    17881 tagaaatcgc tcaagctaac aaggtagcac tttactacga agcagcagtt gctggtggga
    17941 ttccaattct tcgtacttta gcaaattcct tggcttctga taaaattacg cgcgtgcttg
    18001 gagtagtcaa cggaacttcc aacttcatgg tgaccaagat ggtggaagaa ggctggtctt
    18061 acgatgatgc tcttgcggaa gcacaacgtc taggatttgc agaaagcgat ccgacgaatg
    18121 acgtagatgg gattgatgca gcctacaaga tggttatttt gagtcaattt gcctttggca
    18181 tgaagattgc ctttgatgat gtagcccaca agggaatccg caatatcaca ccagaagacg
    18241 tagctgtagc tcaagagctt ggttacgtag tgaaattggt tggttctatt gaggaaactt
    18301 cttcaggtat tgctgcagaa gtgactccaa ccttcctacc taaagcgcac ccacttgcta
    18361 gtgtgaatgg cgtaatgaac gctgtctttg tagaatctat tggtattggt gagtctatgt
    18421 actacggacc aggtgcgggt caaaaaccaa ctgcaacaag tgttgtagct gatattgtcc
    18481 gtatcgttcg tcgtttgaat gatggtacta ttggcaaaga cttcaacgaa tatagccgtg
    18541 acttggtctt ggcaaatcct gaagatgtca aagcaaacta ctatttctca atcttggctc
    18601 tagactcaaa aggtcaggtc ttgaagttgg ctgaaatctt caatgctcaa gatatttcct
    18661 ttaagcaaat ccttcaagat ggcaaagagg gtgacaaggc gcgtgtcgtt atcatcacac
    18721 acaagattaa taaagcccag cttgaaaatg tctcagctga attgaagaag gtttcagaat
    18781 tcgacctctt gaataccttc aaggtgctag gagaataaga tgaagattat tgtacctgca
    18841 accagtgcca atatcgggcc aggttttgac tcggtcggtg tagctgtaac caagtatctt
    18901 caaattgagg tctgcgaaga acgagatgag tggctgattg aacaccagat tggcaaatgg
    18961 attccacatg atgagcgtaa tctcttgctc aaaatcgctt tgcaaattgt accagacttg
    19021 caaccaagac gcttgaaaat gaccagtgat gtccctttgg cgcgcggttt gggttcttcc
    19081 agctcggtta tcgttgctgg gattgaacta gccaaccaac tgggtcaact caacttatca
    19141 gaccatgaaa aattgcagtt agcgaccaag attgaagggc atcctgacaa tgtggctcca
    19201 gccatttatg gtaatctcgt tattgcaagt tctgttgaag ggcaagtctc tgctatcgta
    19261 gcagactttc cagagtgtga ttttctagct tacattccaa actatgaatt acgtactcgc
    19321 gacagccgta gtgtcttgcc taaaaaattg tcttataagg aagctgttgc tgcaagttct
    19381 atcgccaatg tagcggttgc tgccttgttg gcaggagaca tggtgaccgc tgggcaagca
    19441 atcgagggag acctcttcca tgagcgctat cgtcaggact tggtaagaga atttgcgatg
    19501 attaagcaag tgaccaaaga aaatggggcc tatgcaacct acctttctgg tgctgggccg
    19561 acagttatgg ttctggcttc tcatgacaag atgccaacaa ttaaggcaga attggaaaag
    19621 caacctttca aaggaaaact gcatgacttg agagttgata cccaaggtgt ccgtgtagaa
    19681 gcaaaataaa gaatagaaga taggatgggg aaactcttga ccagagggtt tcatatcctt
    19741 tttgtgaaaa gaagtttata ctcaatgaaa atcaaagagc aaactaggaa gctagccgca
    19801 ggctgctcaa aacagtgttt tgaggttgtg gatagaactg acgaagtcag ctcaagacac
    19861 tgttttgagg ttgcagatag aactgacgac gtcagtaaca tatatacggt aaggtgacgc
    19921 taacgtggtt tgaagagatt ttcgaagagt attagttaaa aacgtgataa aggagaaata
    19981 aagatggcag aaatttatct agcaggtggt tgtttttggg gcctagagga atatttttca
    20041 cgcatttctg gagtgctaga aaccagtgtt ggctacgcta atggtcaagt cgaaacgacc
    20101 aattaccagt tgatcaagga aacagaccat gcagaaacgg tccaagtgat ttacgatgag
    20161 aaggaagtgt cactcagaga gattttactt tattatttcc gagttatcga tcctctatct
    20221 atcaatcaac aagggaatga ccgtggccgc caatatcgaa ctgggattta ttatcaggat
    20281 gaagcagatt tgccagctat ctacacagtg gtgcaggagc aggaacgcat gctgggtcga
    20341 aagattgcag tagaagtgga gcaattacgc cactacattc tggctgaaga ctaccaccaa
    20401 gactatctca ggaagaatcc ttcaggttac tgtcatatcg atgtgaccga tgctgataag
    20461 ccattgattg atgcagcaaa ctatgaaaag cctagtcaag aggtgttgaa ggccagtcta
    20521 tctgaagagt cttatcgtgt cacacaagaa gctgctacag aggctccatt taccaatgcc
    20581 tatgaccaaa cctttgaaga ggggatttat gtagatatta cgacaggtga gccactcttt
    20641 tttgccaagg ataagtttgc ttcaggttgt ggttggccaa gttttagccg tccgatttcc
    20701 aaagagttga ttcattatta caaggatctg agccatggaa tggagcgaat tgaagttcgt
    20761 tctcgttcag gcagtgctca cttgggtcat gttttcacag atggaccgcg ggagttaggc
    20821 ggcctccgtt actgtatcaa ttctgcttct ttacgctttg tggccaagga tgagatggaa
    20881 aaagcaggat atggctatct attgccttac ttaaacaaat aaaacagaga gtggggcttc
    20941 ccactttctt catttctaga atatgaatag aagggattta tgaaacacct attatcttac
    21001 ttcaaaccct acatcaagga atcaatttta gcccccttgt tcaagctgtt agaagctgtt
    21061 tttgagctct tggttcccat ggtgattgct gggattgttg accaatcttt acctcaggga
    21121 gatcaaggtc atctctggat gcagattggc ctgctcctta tctttgcagt aattggcgtt
    21181 ttagtggcct tgatagctca attttactca gcaaaggcag cagtaggttt tgctaaggaa
    21241 ttgacaaacg atctttatcg tcatattctt tccttgccaa aggacagcag agaccgtctg
    21301 acaacttcta gtttggttac tcgcttgact tcggatacct accagattca gactggtatc
    21361 aatcaattcc tgcgtctctt tttacgagcg cccattatcg tttttggtgc catttttatg
    21421 gcttatcgaa tctcagctga gttgactttc tggttcttag tcttggttgc cattttgacc
    21481 attgtcattg tagggttatc tcgattggtc aatcctttct acagtagtct cagaaagaaa
    21541 acggaccaac tggttcagga aacgcgccag caattgcaag ggatgcgggt tattcgtgct
    21601 tttggtcaag aaaaacgaga gttacagatt tttcaaaccc ttaaccaagt ttatgctaga
    21661 ttacaagaaa agacaggttt ctggtctagt ttattaacac ctctgaccta tctgattgtc
    21721 aatggaactc ttctcgttat tatctggcaa ggctatattt caattcaagg aggagtgctc
    21781 agtcaaggtg ctctcattgc tcttatcaat tacctcttac agattttggt ggaattggtc
    21841 aagctagcca tgttgatcaa ttccctcaac cagtcctata tctcagtcaa gcgaatcgag
    21901 gaagtctttg ttgaggctcc agaggatatc cattcagagt tagaacaaaa gcaagctacc
    21961 agagataagg ttttacaagt ccaagaattg acttttacct atcctgatgc ggcccagcct
    22021 tctctgagat acatttcctt tgatatgact caaggacaaa ttctaggtat catcggggga
    22081 actggttctg gtaaatcaag cttggtgcaa ctcttacttg gactttatcc agtagacaag
    22141 gggaacattg acctttatca aaatggacgt agtcctctta atttggagca gtggcggtct
    22201 tggattgcct atgtacctca aaaggtcgaa ctctttaaag gaaccattcg ttccaacttg
    22261 actctaggtt tcaatcaaga agtatctgac caggaactct ggcaggcctt ggagattgcg
    22321 caagctaagg attttgtcag tgaaaaggaa ggactcttgg atgctctagt tgaggcaggg
    22381 gggcgaaatt tctcaggtgg acaaaaacaa agattgtcta tcgcccgagc agtcttgcgc
    22441 caagctccgt ttctcatcct agatgatgca acctcggcac tggataccat tacagagtcc
    22501 aagctcttga aagctattag agaaaatttt ccaaacacga gcttaatttt gatctctcaa
    22561 cgaacctcaa ctttacagat ggcggaccag attctcctct tggaaaaagg tgagttgcta
    22621 gctgttggca agcacgatga cttgatgaaa tccagccaag tctattgtga aatcaatgca
    22681 tcccaacatg gaaaggagga ctagaatgaa acgacaaact gtaaaccaga cgctcaaacg
    22741 tttagccgta gatttagcaa gccatccttt cctccttttc ctagcctttc taggaactat
    22801 tgctcaagtt ggcttatcaa tttacctacc tattctgatt gggcaggtca ttgaccaagt
    22861 cctagtggct ggttcatcac cagttttttg gcagattttt ctccagatgc tcttggtggt
    22921 aataggaaat actctggtac aatgggccaa tcctctcctc tataatcgtc taatcttctc
    22981 ttataccaga gatttacggg agcgaatcat ccataagctc catcgtttac cgattgcctt
    23041 tgtagatagg caaggtagtg gagagatggt tagtcgtgta accacggaca tcgaacagtt
    23101 ggcagctggc ttgaccatga tttttaacca atttttcatt ggtgttttga tgattttggt
    23161 cagtattcta gccatgctcc aaattcatct cctcatgact ctcttagtct tgctgttgac
    23221 gccactgtcc atggtgattt cacgctttat tgccaagaaa tcctatcatc tcttccagaa
    23281 gcaaacagag acgaggggaa ttcagactca gttgattgaa gaatcgctta gtcagcagac
    23341 tataatccag tccttcaatg ctcaaacaga atttatccaa agattgcgtg aggctcatga
    23401 caactactca ggctattctc agtcagccat cttttattct tcaacggtca atccttcgac
    23461 tcgctttgta aatgcactca tttatgccct tttagctgga gtaggagctt atcgtatcat
    23521 gatgggttca gccttgaccg tcggtcgttt agtgactttt ttgaactatg ttcagcaata
    23581 caccaagccc tttaacgata tttcttcagt gctagctgag ttgcaaagtg ctctggcttg
    23641 cgtagagcgt atctatggag tcttagatag ccctgaagtg gctgaaacag gtaaggaagt
    23701 cttgacgacc agtgaccaag ttaagggagc tatttccttt aaacatgtct cttttggcta
    23761 ccatcctgaa aaaattttga ttaaggactt gtctatcgat attccagctg gtagtaaggt
    23821 agccatcgtt ggtccgacag gtgctggaaa atcaactctt atcaatctcc ttatgcgttt
    23881 ttatcccatt agctcgggag atatcttgct ggatgggcaa tccatttatg attatacacg
    23941 agtatcattg agacagcagt ttggtatggt gcttcaagaa acctggctca cacaagggac
    24001 cattcatgat aatattgcct ttggcaatcc tgaagccagt cgagagcaag taattgctgc
    24061 tgccaaagca gctaatgcag actttttcat ccaacagttg ccacagggat acgataccaa
    24121 gttggaaaat gctggagaat ctctctctgt cggccaagct cagctcttga ccatagcccg
    24181 agtctttctg gctattccaa agattcttat cttagacgag gcaacttctt ccattgatac
    24241 acggacagaa gtgctggtac aggatgcctt tgcaaaactc atgaagggcc gcacaagttt
    24301 catcattgct caccgtttgt caaccattca ggatgcggat ttaattcttg tcttagtaga
    24361 tggtgatatt gttgaatatg gtaaccatca agaactcatg gatagaaagg gtaagtatta
    24421 ccaaatgcaa aaagctgcgg cttttagttc tgaataagcc attctctttt gaaagtttat
    24481 ggacgaaaaa agttgccttc gagtgacttt tttgttacaa tagctagaaa aattgttcac
    24541 tgtaatactc aatgaaaatc aaagagcaaa ctaggaagct agccgtaggt tgctcaaagc
    24601 acagctttga ggttgtagat aagactgacg aagtcag
//
LOCUS       DAVLDI010000033        24636 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLDI010000033 DAVLDI010000000
VERSION     DAVLDI010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24636
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.033"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            145..510
                     /locus_tag="VXD01_001342"
     CDS             145..510
                     /locus_tag="VXD01_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV0601731.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            586..1527
                     /locus_tag="VXD01_001343"
     CDS             586..1527
                     /locus_tag="VXD01_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV0601732.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHGLSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            1475..2491
                     /locus_tag="VXD01_001344"
     CDS             1475..2491
                     /locus_tag="VXD01_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV0601733.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRAGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            2493..2819
                     /gene="comGC"
                     /locus_tag="VXD01_001345"
     CDS             2493..2819
                     /gene="comGC"
                     /locus_tag="VXD01_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV0601734.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQAKAYKEYHDKNGEA
                     NRKVND"
     gene            2812..3216
                     /locus_tag="VXD01_001346"
     CDS             2812..3216
                     /locus_tag="VXD01_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV0601735.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            3221..3481
                     /locus_tag="VXD01_001347"
     CDS             3221..3481
                     /locus_tag="VXD01_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601736.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            3444..3905
                     /locus_tag="VXD01_001348"
     CDS             3444..3905
                     /locus_tag="VXD01_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0601737.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            3883..4296
                     /locus_tag="VXD01_001349"
     CDS             3883..4296
                     /locus_tag="VXD01_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV0601738.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEIATDSSEKVEKKKSEEKPEKKENS"
     gene            4433..5027
                     /locus_tag="VXD01_001350"
                     /pseudo
     CDS             4433..5027
                     /locus_tag="VXD01_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            5088..6041
                     /locus_tag="VXD01_001351"
     CDS             5088..6041
                     /locus_tag="VXD01_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0601739.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            6092..7282
                     /locus_tag="VXD01_001352"
     CDS             6092..7282
                     /locus_tag="VXD01_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV0601740.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGCSEQQILDIENHAQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKYIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            7431..7802
                     /gene="rnpA"
                     /locus_tag="VXD01_001353"
     CDS             7431..7802
                     /gene="rnpA"
                     /locus_tag="VXD01_001353"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV0601741.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYQEGNGSEKETKVD"
     gene            7777..8601
                     /locus_tag="VXD01_001354"
     CDS             7777..8601
                     /locus_tag="VXD01_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV0601742.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTILIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            8620..9606
                     /locus_tag="VXD01_001355"
     CDS             8620..9606
                     /locus_tag="VXD01_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV0601743.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIETISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            9657..10280
                     /locus_tag="VXD01_001356"
     CDS             9657..10280
                     /locus_tag="VXD01_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV0601744.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLEKQAKILDIPTVKGIYYLAYSDGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            10411..11868
                     /locus_tag="VXD01_001357"
     CDS             10411..11868
                     /locus_tag="VXD01_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0601745.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            11891..12172
                     /locus_tag="VXD01_001358"
     CDS             11891..12172
                     /locus_tag="VXD01_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0601746.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            12249..12734
                     /locus_tag="VXD01_001359"
     CDS             12249..12734
                     /locus_tag="VXD01_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0601747.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            12751..13416
                     /locus_tag="VXD01_001360"
     CDS             12751..13416
                     /locus_tag="VXD01_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV0601748.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            13420..14283
                     /locus_tag="VXD01_001361"
     CDS             13420..14283
                     /locus_tag="VXD01_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV0601749.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            14285..14989
                     /locus_tag="VXD01_001362"
     CDS             14285..14989
                     /locus_tag="VXD01_001362"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV0601750.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVEPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            15166..16839
                     /locus_tag="VXD01_001363"
     CDS             15166..16839
                     /locus_tag="VXD01_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0601751.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINKEIVVQAFLEDI"
     gene            16951..18042
                     /gene="ulaG"
                     /locus_tag="VXD01_001364"
     CDS             16951..18042
                     /gene="ulaG"
                     /locus_tag="VXD01_001364"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV0601752.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            18156..20132
                     /gene="tkt"
                     /locus_tag="VXD01_001365"
     CDS             18156..20132
                     /gene="tkt"
                     /locus_tag="VXD01_001365"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0601753.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            20249..20548
                     /gene="yajC"
                     /locus_tag="VXD01_001366"
     CDS             20249..20548
                     /gene="yajC"
                     /locus_tag="VXD01_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV0601754.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            20595..21023
                     /locus_tag="VXD01_001367"
     CDS             20595..21023
                     /locus_tag="VXD01_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV0601755.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            21025..21435
                     /locus_tag="VXD01_001368"
     CDS             21025..21435
                     /locus_tag="VXD01_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601756.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            21736..24387
                     /gene="adhE"
                     /locus_tag="VXD01_001369"
                     /gene_synonym="adhC"
     CDS             21736..24387
                     /gene="adhE"
                     /locus_tag="VXD01_001369"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV0601757.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTSFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT         7706 a         4424 c         5431 g         7075 t
ORIGIN      
        1 caaatatttt tgtacataag taaatagaaa ttcagtcatc catcagatgg ctggattttt
       61 tatcaaaaaa ttaagaaatg agcatatttc tttccttgtc tggcggaatt ggttataata
      121 tacggtacaa aggaatgaat gaatatgtat cgtgttatag aaatgtacgg agattttgaa
      181 ccgtggtggt tcttagaagg ttgggaagaa gatattgtag caagtagaaa atttgaccag
      241 tattatgatg ctctcaaata ctacaaaact tgctggttta gattggaaca agaatcccct
      301 ctttataaaa gtagaagcga cttgatgacc attttttggg acccggaaga ccaacgctgg
      361 tgtgatgaat gtgatgagta tttacaacaa taccattctt tggctctttt gcaggatgag
      421 caggttatcc cagacgaaaa actacgctca ggctatgaaa aacaaaccag tcaggaaagg
      481 aatcgttctt gccgtatgaa attaaaatag agaaaagtaa cttttttgga gttgcttttt
      541 ttatttttct aacgctttgc gaatagtata ggtgaggagg taagtatggt tcaagaaatt
      601 gcacaagaaa tcattcgctc ggctcggaaa aaaggggcgc aagacattta ttttgtcccc
      661 aagttagacg cctatgagct tcatatgagg gtaggagacg agcgctgtaa aattggtagc
      721 tatgattttg aaaagtttgc agccgttatc agtcacttta agtttgtggc gggtatgaat
      781 gtgggagaaa aaagacgtag tcaactgggt tcctgtgatt atgcctatga ccagaagatg
      841 gcgtctctac gtttatctac tgtaggcgat tatcgggggc atgagagttt ggttatccgt
      901 ttgttgcacg atgaggagca ggacttgcat ttttggtttc aggatattga agaattaggc
      961 aagcagtaca ggcaacgggg actctatctt tttgctggtc cggttggaag tggtaagacg
     1021 accttgatgc atggattgtc caagtcactc tttaaaggac agcaagttat gtccatcgaa
     1081 gatcctgtcg aaatcaagca ggacgatatg cttcagttgc agttgaacga agcaatcggc
     1141 ctaacctatg aaaatctaat caaactttcc ttgcgtcatc gaccagatct cttgattatc
     1201 ggagaaattc gtgacagcga gacggcgcgt gcagtggtca gagctagttt gacaggtgcg
     1261 acagtctttt caaccattca cgccaagagt atccgaggtg tttatgagcg tctgctggag
     1321 ttgggtgtga gtgaagaaga attggcagtt gttctgcaag gagtctgcta ccagagatta
     1381 atcgggggag gaggaatcgt tgactttgca aacagagatt atcaagaaca ccaagcagcc
     1441 aagtggaatg agcaaattga ccagcttctt aaagatggac atatcacaag tcttcaggct
     1501 gagacggaaa aaattagcta cagctaagca aaaaaatatc atcaccctat ttaacaatct
     1561 cttttctagc ggttttcatc tggtggagac tatctccttt ttagatagga gtgctttgtt
     1621 ggacaagcag tgtgtgatcc agatgcgtgc gggcttgtct caagggaaat cattctcaga
     1681 aatgatggaa agtttgggat gttcaagtac cattgtcact cagttatccc tagccgaagt
     1741 tcatggaaat ctccacctga gtttgggaaa gatagaagaa tatctggaca atctggctaa
     1801 ggtcaagaaa aaattaattg aagtagcgac ctatcctttg attttgctgg gttttcttct
     1861 cttaattatg ctggggctac ggaattacct gctcccacaa ctggatagta gcaatattgc
     1921 cacccaaatt atcggtaatc tgccccaaat ttttctaggc atggtagggc ttgtttccgt
     1981 gcttgccctt ttagcactaa ctttttataa aagaagttct aagatgagtg tcttttctat
     2041 cttagcacgc cttcccttta ttggaatctt tgtgcagacc tacttgacag cctattatgc
     2101 acgtgaatgg gggaatatga tttcacaggg aatggagctg acgcagattt ttcaaatgat
     2161 gcaggaacaa ggttcccagc tctttaaaga aatcggtcaa gatctggctc aaaccctgaa
     2221 aaatggccgt gaattttctc agacgatagg aacctatcct ttctttagga aggaattgag
     2281 tctcatcata gagtatgggg aagttaagtc caagctgggt agtgagttgg aaatctatgc
     2341 tgaaaaaact tgggaagcct tttttacccg agtcaaccgc accatgaatt tggtgcagcc
     2401 actggttttt atctttgtgg cactgattat cgttttactt tatgcggcaa tgctcatgcc
     2461 catgtatcaa aatatggagg taaattttta aaatgaaaaa aatgatgaca ttcttgaaaa
     2521 aagctaaggt taaagctttt acattggtgg aaatgttggt ggtcttgctg attatcagcg
     2581 tgcttttctt gctctttgta cctaatctga ccaagcaaaa agaagcagtc aatgacaaag
     2641 gaaaagcagc tgttgttaag gtggtggaaa gccaggcaga actttatagc ttggaaaaga
     2701 atgaagatgc tagcctaagc aagttaaaag acgatgggcg aatcacggaa gaacaggcta
     2761 aagcttataa agaataccat gataaaaatg gagaagcaaa tcgtaaagtc aatgattaag
     2821 gcctttacca tgctggaaag tctcttggtt ttgggtcttg tgagtatcct tgccttgggc
     2881 ttgtccggct ctgttcagtc cacttttgcg gcggtagagg aacagatttt ctttatggag
     2941 tttgaagaac tctatcggga aacccaaaaa cgcagtgtag ccagtcagca aaagactagt
     3001 ctgaacttag atgggcagac gcttagcaat ggcagtcaaa agttgacagt tcctaaagga
     3061 attcaggcac catcaggcca aagtattaca tttgaccgag ctgggggcaa ttcgtccctg
     3121 gctaaggttg aatttcagac cagtaaagga gcgattcgct atcaattata tctaggaaat
     3181 ggaaaaatta aacgcattaa ggaaacaaaa aattagggca gtgattttac tggaagcagt
     3241 agtcgctcta gctatctttg ccagcattgc gaccctcctt ttgggacaaa ttcaaaaaaa
     3301 taggcaagag gaagcaaaaa tcttgcaaaa ggaagaagtc ttgagggtag ctaagatggc
     3361 cctgcagacg gggcaaaatc aggtaagcat caacggagtt gagattcagg tattttctag
     3421 tgaaaaagga ttggaggtct accatggttc agaacagttg ttggcaatca aagagccata
     3481 aggtcaaggc ttttaccttg ttagaatccc tacttgccct cattgtcatc agtgggggat
     3541 tactcctttt tcaaactatg agtcagctcc tcatttcaga agttcgctac cagcaacaaa
     3601 gcgagcaaaa ggagtggctc ttgtttgtgg accaacttga ggcagaatta gaccgttcgc
     3661 agttcgaaaa agtagaaggc aatcgcctat acatgaagca agatggcaag gacatcgcca
     3721 tcggtaagtc aaagtcagac gattttcgta aaaccgatgc tagtggacgg gggtatcagc
     3781 ctatggttta tggcctcaaa tcagctcaga ttacagagga caatcaactg gttcattttc
     3841 gtttccagtt tcaaaaaggc ttagaaaggg agttcatcta tcgtgtggaa aaagaaaaaa
     3901 gttaaggcag gtgttctcct ctacgcagtc accatagcag ccatctttag tcttttgttg
     3961 caattttact tgaaccgaca agtcgcccac tatcaagact atgctttgaa taaagaaaaa
     4021 ttggttgctt ttgcaatggc taaacgaacc aaggataaag ccgagcaaga aagtggggaa
     4081 caggtcttta atctaggtca ggtaagctat caaaacaaga aaacaagctt ggtgacgact
     4141 gttcgtacgt ctaagagcca atatgagttt ctgtttcctt cagtcaaaat caaagaagag
     4201 aaaagagata aaaaggaaga gatagcgacc gattcaagcg aaaaagtgga gaagaaaaaa
     4261 tcagaagaga agcctgaaaa gaaagagaat tcctagtcaa ttcaactata atgcgttgaa
     4321 tccagaatag tccactatag tttctataaa attgctggaa atggatatta agctccaatt
     4381 catttgttta tatcttattt cagtttacta tactttgtgc taaactaaag atatgaaaca
     4441 tgattttaac cacaaagcag aaactttcga ttcccctaaa aatatcttcc tcgcaaactt
     4501 ggtatgtcaa gcagccgaga aacagattga tcttctatca gacaaagaaa ttttagattt
     4561 cggtggtggc acgggtctat tagccttgcc cctagcccct agccaagcag gctaagtcag
     4621 tcactcttgt agacatttct gagaaaatgt tggagcaagc tcgtttgaaa gtggagcagc
     4681 aagcaatcaa gaatatccag tttttggagc aagatttacc gaaaaatccc ttggagaaag
     4741 agtttgattg ccttgctgtt agtcgggttc ttcatcatat gcctgatttg gatgcggctc
     4801 tctcactgtt tcatcaacat ttgaaggaag atgggaaact catcattgct gattttacca
     4861 agacagaagc taatcatcat ggatttgatt tagctgaact ggaaaacaag ctaattgagc
     4921 atggtttttc atctgtgcat agtcagattc tctatagcgc tgaagaccgg tttcaaggaa
     4981 atcactcaga attcttttta atagtagccc aaaaatcact cgcctagtca gggagtgatt
     5041 tttctataag gatggaaaaa agaagggaaa tttgataaga taggaatatg gattttgaaa
     5101 aaattgaaca agcttatacc tatttactag agaatgtcca agtcatccaa agtgatttgg
     5161 cgaccaactt ttatgacgcc ttggtggagc aaaacagcat ctatctggat ggtgaaactg
     5221 agctaaacca ggtcaaagac aacaatcagg cccttaagcg tttagcacta cgcaaagaag
     5281 aatggctcaa gacctaccag tttctcttga tgaaggctgg gcaaacagaa cccttgcagg
     5341 ccaatcacca gtttacaccg gatgctattg ctttgctttt ggtgtttatt gtggaagagt
     5401 tgtttaaaga ggaggaaatt actatcctcg aaatgggttc tgggatggga attctaggcg
     5461 ctactttctt gacctcgctt gataaaaagg tggattactt gggaatggaa gtggatgatt
     5521 tactgattga tctggcagct agcatggcag atgtaattgg tttgcaggct ggctttgtcc
     5581 aaggagatgc cgttcgtcca caaatgctca aagaaagcga tgtggtcatc agtgacttgc
     5641 ctgttggcta ttatcctgat gatgccgttg cgtcgcgcca tcaagttgct tctagccaag
     5701 aacatactta cgcccatcac ttgctcatgg aacaagggct taagtacctc aagtcagacg
     5761 gatacgctat ttttctagct ccgagtgatt tgttgaccag tcctcaaagt gatttgttaa
     5821 aagaatggct gaaagaagag gcgagtctgg ttgctatgat tagtctgcct gaaaacctct
     5881 ttgctaatgc caaacaatct aagactattt ttatcttaca gaagaaaaat gaaatagcag
     5941 tagagccttt tgtttatcca cttgctagct tgcaagatgc aagtgtttta atgaaattta
     6001 aagaaaattt tcaaaaatgg actcaaggta ctgaaatata aaatagattt tgttataata
     6061 gttgaaaacg cttaaaaagg ggtatcatgt tatgacaaaa acaattgcaa tcaatgcagg
     6121 aagttcaagt ttgaaatggc aattatactt aatgccagaa gaaaaagtat tggcgaaagg
     6181 tttgattgaa cgtatcggtt tgaaagattc aatttcaact gtaaaatttg acggctgttc
     6241 tgaacaacaa attttggata ttgaaaatca tgcacaagcc gttaaaattt tattggatga
     6301 cttgattcgt ttcgatatta tcaaggctta tgacgagatt acaggtgttg gacatcgtgt
     6361 tgttgctggt ggagaatatt tcaaagaatc aacagttgtt gagggagatg ttttagaaaa
     6421 agttgaagag ttgagtttgt tggctcctct acacaacccg gccaatgcag caggtgttcg
     6481 tgccttcaag gaattgttgc cagacattac cagtgtagtt gtttttgata cttccttcca
     6541 cacaagtatg ccagagaaag cttatcgcta ccctctacca acaaaatatt acacagaaaa
     6601 caaggttcgt aaatacggtg ctcatggtac aagtcaccag tttgtagcag gagaggctgc
     6661 aaaactcttg ggacgtccat tagaagactt gaagttaatt acctgtcata ttggtaacgg
     6721 aggctcaatt acagctgtga aagccggcaa atctgtagac acttctatgg ggttcactcc
     6781 tcttggtggt attatgatgg gaacgcgtac aggggatatt gatccagcta tcattcctta
     6841 tttaatgcaa tatacagagg attttaacac accagaagat atcagtcgtg ttcttaaccg
     6901 tgaatcaggt cttttgggag tttctgctaa ttctagcgat atgcgcgata tagaagcagc
     6961 tgtagcagaa gggaatcacg aggctagctt ggcttatgaa atgtatgttg accgtatcca
     7021 aaaatatatc ggtcagtacc ttgcagtgct aaatggagca gatgccattg ttttcacagc
     7081 aggtgtcggt gaaaatgcag agaatttccg tcgtgatgta atctcaggga tttcgtggtt
     7141 tggttgtgat gttgatgatg aaaagaatgt ctttggcgtt acaggagaca tctcaacaga
     7201 ggcagctaaa atccgtgtct tggttattcc aacagatgaa gaattagtca ttgcccgtga
     7261 cgttgaacgc ttgaaaaaat aagtgaaact aaaaaaatat tcaatacaag gagttgggaa
     7321 agttattttt ccagcttctt tttctgatga aattgtccaa aaccttgcta tgattggctt
     7381 ttttgaaaaa tatggtataa tagtagtaat ttaatagatg gagttgagtt ttgaagaaaa
     7441 actttcgtgt aaaaagagag aaagatttta aggcgatttt caaggagggg acaagttttg
     7501 ctaatcgcaa atttgtggtc taccaattag aaaaccagaa aaaccatttt cgagtaggtc
     7561 tatcagttag caaaaaactg gggaatgccg tcactagaaa tcaaattaag cgacggattc
     7621 ggcatattat ccagaatgca aaagggagtc tggtagaaga tgtcgacttt gttgtcattg
     7681 ctcgaaaagg agtcgaaacc ttgggatacg cagagatgga gaaaaatcta ctccacgtat
     7741 taaaattatc aaagatttac caggaaggaa atgggagtga aaaagaaact aaagttgact
     7801 agtttgctag gactgtctct gttaatcatg acagcctgtg cgactaatgg ggtaactagc
     7861 gatattacag ccgaatcggc tgatttttgg agtaaattgg tttacttctt tgcggaaatc
     7921 attcgctttt tatcgtttga tattagtatc ggagtgggga ttattctctt tacgatcttg
     7981 attcgtacag tcctcttgcc agtctttcag gtgcaaatgg tggcttctag gaaaatgcag
     8041 gaagctcagc cacgcattaa ggcgcttcga gaacaatatc caggtcgaga tatggaaagc
     8101 agaaccaaac tagagcagga aatgcgtaaa gtatttaaag aaatgggtgt cagacagtca
     8161 gactctcttt ggccgatttt gattcagatg ccggttattt tggccctgtt ccaagcccta
     8221 tcaagagttg actttttaaa gacaggtcat ttcttatgga ttaaccttgg tagtgtggat
     8281 acaacccttg ttcttccgat tttagcagca gtattcacct ttttaagtac ttggttgtcc
     8341 aacaaagctt tgtctgagcg aaatggcgct acgactgcga tgatgtatgg gattccagtc
     8401 ttgattttta tctttgcagt ttatgcgcca ggtggagtcg ccctatactg gacagtgtct
     8461 aatgcttatc aagtcttgca aacctatttc ttgaataatc cattcaagat tatcgcagag
     8521 cgcgaggccg tagtacaggc acaaaaagat ttggaaaata gaaaaagaaa agccaagaaa
     8581 aaggctcaga aaacgaaata aataaggagg aatctggtaa tggtagtatt tacaggttca
     8641 actgttgaag aagcaatcca gaaaggattg aaagaattag atattccaag aatgaaggct
     8701 catatcaaag tcatttctag ggagaagaaa ggctttcttg gtctatttgg taaaaaacca
     8761 gcccaagtgg atattgaaac gattagtgaa acgactgttg tcaaagcaaa tcaacaggta
     8821 gtaaaaggcg ttccgaaaaa aatcaatgat ttgaacgagc ctgtgaagac ggttagtgaa
     8881 gaaaccgttg accttggtca tgtggttgat gctattaaaa aaatagagga agaaggtcaa
     8941 ggcatttctg atgaagtcaa ggctgaaatc ttaaaacatg aaagacatgc cagcactatc
     9001 ttagaagaaa ctggtcacat tgagatttta aatgaacttc aaatcgagga agcgatgagg
     9061 gaagaagcag gcgctgatga ccttgaaact gagcaagacc aagctgaaag tcaagaacta
     9121 gaagacttgg gcttgaaagt tgaaacgaac tttgatattg aacaagtagc tacggaagta
     9181 atggcttatg ttcaaacgat tattgatgac atggatgttg aggctacact ttcaaatgat
     9241 tataaccgtc gtagcatcaa tttgcaaatt gatactaacg aaccaggtcg tattatcggc
     9301 taccatggta aagtcttgaa ggccttgcaa ctgttggctc aaaattatct ttacaactgc
     9361 tattcaagaa ccttctatat cactattaat gtcaatgatt atgttgaaca ccgtgcagaa
     9421 gtcttgcaga cctatgcgca aaaattggcg attcgtgttt tagaagaagg acgtagtcat
     9481 caaacagatc caatgtcgaa tagtgaacgc aagattatcc accgtattat ttcacgtatg
     9541 gatggcgtga ccagttactc tgaaggtgat gagccaaatc gctatgtcgt tgtagataca
     9601 gaataagtaa aatcagggtt gacctgattt tttgctagct agaggaggtt aaactgatgt
     9661 tgaataagat aagagactat ctagactttt ctggtttgca gtaccgtagt cctgataaag
     9721 cgggggcaga gcgagagaag atgctggcgt tccgccacaa aggacaagag gcccgaaagg
     9781 cttttacaga actggccaaa gcctttcaag caagccatcc agaatggcaa ctccaacaga
     9841 ctagtcagtg gatgaatcag gcccagcgtt tgagaccaca tttttgggtt tatctacaga
     9901 gagacggaca agtgacagaa cctatgatgg ccttacgttt gtatgggaca tctactgact
     9961 ttggaatttc tttggaagtc agtttcatcg aacgtaagaa ggatgagcaa actttagaga
    10021 aacaggccaa gattttagac ataccaaccg ttaaaggaat ttattatcta gcctactctg
    10081 atggccaaag tcaacggtgg gaggcgaacg aagaaaagcg tcgtacttta cgcgagaagg
    10141 tgagaagtca agaagttcga aaagttttag tgaaggtaga tgttcctatg acagaaaatt
    10201 cgtctgaaga agaaatcgta gaaggcttat tgaagtctta ttctaaaatt cttccctatt
    10261 atctagctac gagaaaataa gataatttgt aaaacatcat aaatcataca gtccaagagt
    10321 gaacagtccg ctgtgtaatt cttggtcttt ttgtttgcgc tttcgcatta tataataaac
    10381 ttacaaaaac aattcaaaag gagaacaatt atggaagtcg tttcaagtgt tctaaattgg
    10441 ttttctagca atattttgca gaatcccgca tttttcgtag gtttattggt gttgatagga
    10501 tatgcacttt tgaaaaaacc tgcccatgac gttttttcag ggtttgttaa agcaacagta
    10561 gggtatatgt tgcttaacgt gggtgctggt ggtttggtta caacctttcg tccaatctta
    10621 gcagctctta actacaaatt ccaaattggt gcagcggtta tcgaccctta ctttggactt
    10681 gctgcagcaa acaacaaaat tgcagcagag tttccagatt ttgttggaac tgcaactaca
    10741 gctctattga ttggttttgg aataaatatc ttgctcgtag ctcttcgaaa gattacgaag
    10801 gtaagaaccc tctttattac tggtcacatc atggtacaac aagctgcaac agtatctctt
    10861 atggttctat tcttagtacc acaattgcgc aatgcttacg gtacagcagc gattggtatc
    10921 atctgtggac tttactgggc agttagttca aatatgactg ttgaggcaac tcaacgcttg
    10981 actggtggtg gcggatttgc gattggtcac caacagcaat ttgcaatctg gtttgtagat
    11041 aaagtagcag gacgctttgg taagaaagaa gaaagtttag acaatcttaa attacctaag
    11101 ttcctctcaa tcttccacga tacagttgtt gcatctgcta ccttgatgct cgtattcttc
    11161 ggggccattc ttttaatctt gggtccagac attatgtcta ataaagaagt catcacttca
    11221 ggaactctat tcaatcctgc taaacaagat ttctttatgt acattatcca aacagccttt
    11281 accttctcag tttacttgtt cgttttgatg caaggtgtcc gaatgttcgt atctgagtta
    11341 acaaacgctt tccaaggtat ttcaaacaaa ttgttgccag gttcattccc agcggttgac
    11401 gttgcagctt cttatggatt tggttctcca aatgctgtct tgtcaggatt tacctttggt
    11461 ttgattggtc aattgattac aattgtcttg ctcatcgtct ttaaaaatcc gattcttatt
    11521 attacaggat ttgtaccagt gttctttgac aatgcagcca ttgcggtcta cgctgataaa
    11581 cgcggcggat ggaaagcggc tgttatcctt tcctttatat caggtgtcct tcaagttgct
    11641 ctaggagctc tttgtgtggc ccttctcgat ttggcatctt atggtggcta ccatggaaat
    11701 atcgactttg aattcccatg gcttggattt ggatatatct tcaaatacct tggtattgtt
    11761 ggttatgtac ttgtgtgtct cttcttgctt gttattcctc aacttcaatt tgccaaagca
    11821 aaagataaag agaaatatta caacggtgaa gttcaagaag aagcttagta tctagaaaag
    11881 gagaaataaa atggttaaag tattagcagc gtgcggaaat ggaatgggtt catcaatggt
    11941 tatcaagatg aaggttgaaa atgctctccg taagcttaat caaacagatt ttacagtcaa
    12001 ttcatgcagt gtcggtgaag ctaaaggttt agcagtagga tatgacatcg taatcgcttc
    12061 tcttcatttg attcaagaat tggaagggcg aactaatggg aagttaattg gacttgataa
    12121 cttgatggat gataaagaaa tcaccgaaaa actcagtcaa gcactacagt aaaaggttgg
    12181 agggggctgg acagaaactg agagttatcg tttctgtcct tctccctctt taaataaagg
    12241 aggcagatat gaatttaaaa caagctttaa ttgacaatga ctcgatccga ctaggtttag
    12301 aggctaacga ttggaaagaa gcagtcaagg tagcagtaga tcccttgatt gaaagtgggg
    12361 caattttgcc agagtattac gatgctatca ttgaatcgac tgaagagtat gggccttact
    12421 atatcttgat gccaggtatg gctatgcccc acgctagacc tgaagctggt gtgcaaagtg
    12481 atgccttttc attaattacc ttacaaaatc ctgttgtatt ttcagatggg aaagaggtat
    12541 ctgttttgtt ggcactagca gcaacaagtt caaaaattca cacaagtgta gccattccac
    12601 aaattattgc cctgtttgaa ttagaagatt ctattgcacg tttacaggct tgccagacta
    12661 aagaagatgt cttggctatg attgaagaat ctaaggatag cccttatctc gaaggattgg
    12721 atttggaaag ttagaaagag gaataaagaa atgacaaaaa gaatacctaa tttacaagtt
    12781 gcattagacc attcagactt gcaaggagcg attaaagcag ctgtttctgt tggtcaggaa
    12841 gtagatatta tcgaagctgg aactgtttgc ttgcttcaag ttggaagtga actggctgaa
    12901 gtcttgcgta gccttttccc agataagatt attgtggcag acacaaaatg tgctgatgct
    12961 ggtggaacag ttgctaaaaa taatgcggtt cgtggagcag actggatgac ttgtatctgt
    13021 tgtgcaacca tccctactat ggaagcagct ctaaaggcta tcaagactga acgaggagaa
    13081 cgaggcgaaa tccagatcga gctttatggc gattggactt ttgaacaagc tcagctttgg
    13141 ctagatgcag gtatctcaca agctatttat caccaatctc gtgatgctct tcttgctggt
    13201 gaaacttggg gtgaaaaaga ccttaataag gttaaaaaac tcattgacat gggcttccgt
    13261 gtatctgtaa caggtggtct agatgtagat actctcaaac tctttgaagg tgttgatgtc
    13321 tttaccttta tcgcaggtcg tggaattaca gaggctgtgg atccagcagg agcagcgcgt
    13381 gccttcaagg atgaaatcaa acgaatttgg gggtaaatca tggtacgtcc aattggaatt
    13441 tatgaaaagg caaccccaac acactttact tggctagaac gtttaaattt tgccaaggag
    13501 ttaggctttg attttatcga gatgtctatt gacgaacgtg acgagcgttt agcaagactt
    13561 gactggagta aggaagaacg cttggaagtt gtcaaagaaa tctatgaaac tggtgttcgt
    13621 attccttcta tctgtttttc aggccatcgt cgctacccat tgggatcaaa agattcagtt
    13681 ctagaggaaa aatctctaga actcatgaaa aaatgtatcg aattagctca agacttggga
    13741 gttcgtacga ttcaattagc tggttacgat gtttactatg aggaaaagtc accccagaca
    13801 cgccaacgtt ttatcaaaaa tttgagaaaa gcctgtgact gggctgaaga agctcaggtg
    13861 gtacttgcta ttgaaattat ggatgatcct ttcatcaata gcatcgaaaa atatttggct
    13921 atagaaaaag agattgactc tcccttcctc tttgtatatc cagatattgg taatgtgtct
    13981 gcatggcata atgatatcta tagtgagttt tatcttggtc atcatgccat cgcagctctc
    14041 catctcaagg atacttatgc agtgacagaa agttcaaagg gccagttccg agatgtacct
    14101 tttgggcaag gttgtgtcaa atgggaagaa gctttcgata ttttaaagga aaccaattat
    14161 aatggacctt tcctaatcga aatgtggtct gaaaattgtg aaacagtaga agaaacacgc
    14221 gcagccattc aagaggcgca agcttttctc tatccactca ttaagaaagc aggtttgatg
    14281 taagatgaat caagtaatca atgctatgcg taaacgagtc tgtgatgcca atcaatcatt
    14341 gccaaaacat ggacttgtca aatttacctg ggggaatgta tctgaagtca atcgcgaact
    14401 cggtgtcatt gttatcaaac catcaggcgt ggattatgac gaattgacac ctgaaaacat
    14461 ggtagtgact gatctagatg gtaagatcct agaaggggat ttaagaccat cttccgacct
    14521 cccaactcat gtgcaattat ataaggcttg gtcagaaatt ggtagtgtgg ttcacaccca
    14581 ttcgacagaa gctgttgctt gggctcaggc aggtcgtgat attcctttct acggaacaac
    14641 ccatgcagat tatttctacg gttcaatccc ttgcgcccgt agtttgacca aggacgaagt
    14701 agaagtggcc tatgaaaaag atactggcct ggttatcgta gaagagtttg aacatcgcgg
    14761 acttaacccg gttgaagtac caggaattgt tgtacgcaat cacggtccat tcacctgggg
    14821 caaaaatcca gagaatgctg tttatcactc tgtcgtacta gaggaagtat caaagatgaa
    14881 tcgctttaca gaacaaatca atccaagagt tgaacctgct ccccagtaca tactagaaaa
    14941 acactaccaa cgtaaacatg gaccaaatgc ttattatggt caaaagtaag aacgatgaag
    15001 gaggagaaaa agataaattt agctcctctt tttacatttg atttttattg agagtaaagt
    15061 tggagttgaa gtaattttga aagatttttt agaaatagcg cttgatatat atggtaaaat
    15121 aaaaagaatt gctgtgatat caatagattt gggggatttt ttaatatggt actggataag
    15181 gcaagttgtg atttgcttca atatttgatg gatcaagaaa cgtccaaaac gattatggcg
    15241 atttcgaaag atttgaaaga gtcaagaagg aaaatttatt atcacattga caaaatcaat
    15301 gctgctctgg ttgacgaggc gcttcacatc attagtattc cacgaattgg tattcactta
    15361 acggaagagc agagagatgc ttgttgtaaa ctattatcgg aagtagattc gtacgattat
    15421 atcatgagtg cgcatgaacg tatgatgata atgttactat ggataggtat ttctaaagaa
    15481 cgtattacga ttgaaaaatt gatagagtta acagaggtat ctaggaatac tgttctcaat
    15541 gatttgaata gtattcgtta tcaactaact ttggaacaat atcaggtgac cttgcaagtg
    15601 agcaagtcac agggatacca ccttcatgcc caccctctta ataaaattca gtatcttcaa
    15661 tcgcttctat atcatatttt tatggaagaa aatgccactt ttgtatctat tttagaagat
    15721 aagatgaaag agaggttaga tgatgagtgt ttgctttctg ttgaaatgaa ccaatttttt
    15781 aaggaacagg ttcctttagt tgaacaagat ttagggaaga aaataaacca tcatgaaata
    15841 acttttatgt tgcaggttct accttatttg ctgttaagct gtcataatgt tgaacagtat
    15901 caagaaagac atcaggatat agagaaagaa ttttctttga taagaaaaag aatagagtat
    15961 caggtgtcta agaaattagg agaacggttg tttcaaaagt ttgaaatttc tttgtcagga
    16021 cttgaagttt ctcttgtagc tgttctcctc ctctcctatc gtaaagattt ggatattcat
    16081 gcagaaagtg atgattttcg gcaattaaaa cttgctttag aagaatttat ctggtatttt
    16141 gaatcacaaa tccgaatgga gattgagaac aaggatgatt tgttacgaaa tttgatgatc
    16201 cactgtaaag ccttgttatt tagaaagact tacggtattt tttctaaaaa tcctctaaca
    16261 aaacaaattc gatccaagta tggagaatta tttttagtca ctagaaaatc tgcggaaatt
    16321 ttagaaggag catggtttat tcggctaaca gacgatgata ttgcctattt gacgattcat
    16381 attggaggat ttttaaagta tacaccatcg tctcaaaaaa atatgaaaaa agtttatctc
    16441 gtttgtgatg aaggtgttgc ggtttcgaga cttttgctga aacaatgcaa actttatttt
    16501 ccaaatgagc aaattgacac tgtatttaca acagaacaat ttaagagtgt ggaagatatt
    16561 gcacaagttg atgtagtgat tactactaat gatgatttgg atagcagatt tccgatttta
    16621 agggttaatc ctatccttga agcagaagat attttgaaaa tgctagacta tcttaaacac
    16681 aatatatttc gtaataagag caaaagtttc agtgaaaatc tttctagtct tatttcgtct
    16741 tatattgtag acagcaagtt ggctagtaag ttccaagaag aggttcaaac acttataaat
    16801 aaagaaatag tagttcaagc ttttttggaa gatatttgaa ggacagtcca atgatgaaca
    16861 caaacctgtg tttttcttgg tcttttttag tgttttgaag ggtggtatac taatctcaaa
    16921 gataacaatt atatccaaag gaggcaacat atgccaaacg tcaaagaaat tacaagagag
    16981 tcatggattt tagccacttt cccagagtgg ggaacatggt tgaacgaaga aatcgaagaa
    17041 gaagtcgtac ctgaaggcaa ctttgccatg tggtggctag gcaactgtgg tacttggatt
    17101 aagacaccag ctggtgctaa cgttgtcatg gacctttggt caaaccgtgg aaaatcaacc
    17161 aaaaaagtga aagatatggt tcgtgggcac caaatggcaa atatggcagg tgttcgtaag
    17221 ttgcaaccaa acttgcgtgt tcagccaatg gttatcgatc catttgctat caacgaacta
    17281 gactattact tagtttcaca cttccacagt gatcatatcg acccatacac agctgcagca
    17341 attctcaaca atcctaagtt agagcatgtt aagtttatcg gtccttacca ctgtggacga
    17401 atctgggaag gatggggtgt tccaaaagaa cgtatcatcg ttgttaaacc aggtgacact
    17461 atcgaattaa aagatatgaa gattcatgca gtagaatcat ttgaccgtac ttgcttggta
    17521 actctcccag tgaacggtgc tgatgagaca ggcggtgaac ttgctggctt ggctgttaca
    17581 gatgaagaaa tggctcaaaa ggctgttaac tatatctttg aaacaccagg tggaaccatc
    17641 tatcatggtg cagattctca cttctcaaac tattttgcaa aacatggtaa agactttaaa
    17701 attgatgttg ctttgaataa ctatggtgaa aatccggtag gtatccaaga caaaatgaca
    17761 tctatcgacc ttcttcgtat ggcagaaaat ctgcgtacca aagtcattat cccagttcac
    17821 tatgatatct ggtctaactt catggcttct actaatgaga ttctagaact ttggaaaatg
    17881 cgaaaagatc gcttgcaata cgatttccat ccatttatct gggaagttgg cggtaagtac
    17941 acttatcctc aagatcaaca cttagtagaa taccatcatc cacgtggttt tgatgattgt
    18001 tttgaacaag actctaacat tcaatttaaa gctttgctat aatataaaaa tattctttgg
    18061 aggttatccg tatgttgcat gatacggata attttcatat aatagtaaaa tagaatgtgt
    18121 gattcaataa tcacctcaaa tagaaaggaa attctatgtc aaatctatct gttaatgcaa
    18181 ttcgttttct aggtattgac gccattaata aagccaactc aggtcatcca ggtgtggtta
    18241 tgggagcggc tccgatggct tacagcctct ttacaaaaca acttcatatc aatccagctc
    18301 aaccaaactg gattaaccgc gaccgcttta ttctttcagc aggtcatggc tcaatgctcc
    18361 tttatgctct tcttcacctt tctggttttg aagatgtcag catggatgag attaagagct
    18421 tccgtcaatg gggttcaaaa acaccaggtc acccagaatt tggtcatacg gcagggattg
    18481 atgctacgac aggtcctcta gggcaaggga tttcaactgc tactggtttt gcccaagcag
    18541 aacgtttctt ggcagccaaa tataaccgtg aaggctacaa tatctttgac cactatactt
    18601 acgttatctg tggagacgga gacttgatgg aaggtgtctc aagcgaggca gcttcatacg
    18661 caggcttgca aaaacttgat aagttggttg ttctttatga ttcaaatgat atcaacttgg
    18721 atggtgagac aaaggattcc tttacagaaa gtgttcgtga ccgttacaat gcctacggtt
    18781 ggcatactgc cttggttgaa aatggaacag acttggaagc catccatgct gctatcgaaa
    18841 cagcaaaagc ttcaggcaag ccatctttga ttgaagtgaa gacggttatt ggatacggtt
    18901 ctccaaacaa acaaggaact aatgctgtac acggcgcccc tcttggagca gatgaaactg
    18961 catcaactcg ccaagccctc ggttgggact acgaaccatt tgaaattcca gaacaagtat
    19021 atgctgattt caaagaacat gttgcagacc gtggcgcatc agcttatcaa gcttggacta
    19081 aattagttgc agattataaa gaagctcatc cagaactggc tgcagaagta gaggccatca
    19141 tcgacggacg tgatccagtc gaagtgactc cagcagactt cccagcttta gaaaatggtt
    19201 tttctcaagc aactcgtaat tcaagtcaag atgccttgaa tgttgtggca gctaaattac
    19261 caaccttcct aggtggatca gctgaccttg ctcactcaaa catgacttat atcaagacgg
    19321 atggacttca agacgatacc aatcgcttga atcgtaacat tcagtttggt gttcgtgaat
    19381 ttgcaatggg aacaatcttg aacgggatgg cccttcatgg tggacttcgt gtatacggtg
    19441 gaactttctt cgtcttctct gactatgtga aggcagctgt ccgcttgtca gccttacaag
    19501 gacttcctgt gacttatgtc tttacccatg attcaatcgc agttggggaa gatggtccga
    19561 ctcacgaacc agttgagcat ttagcaggtc ttcgtgctat gccaaatcta aatgttttcc
    19621 gtccagcaga tgcgcgtgaa actcaagcag cttggtacct tgcagtgaca agtgagaaaa
    19681 caccaactgc ccttgtcttg acacgtcaaa acttgactgt tgaagatgga acagacttcg
    19741 acaaggttgc taaaggtgct tatgttgtat atgaaaatgc agccgacttt gataccatct
    19801 tgattgcgac aggttcagag gttaatcttg ctgtctcagc tgctaaagaa ttggctagtc
    19861 aaggcgaaaa aatccgcgta gtcagcatgc catctacaga tgtctttgat aaacaagatg
    19921 cagcttacaa ggaagaaatt cttccaaatg cagtccgccg tcgtgttgca gtcgaaatgg
    19981 gtgcaagtca aaactggtac aaatatgttg gtctcgatgg tgccgttcta ggtattgata
    20041 ccttcggagc ctctgcccca gcaccaaaag tattggcaga atatggcttt actgtagaaa
    20101 atcttgtaaa aattgttcga aacttgaaat aatcctaaaa atcagggcgt aagctctggt
    20161 ttttcttacc agaaaagtaa ggtacaatct tgtaaaagta gctgaaattt gatatagtag
    20221 tcctatgtaa aagacaaagg agaaaacaat gaatccaaat attacttttt taatcatgct
    20281 tgtaggtatg atggccttga tgttctttat gcaacgttct caaaagaaac aagctcaaaa
    20341 gcgtatggaa agcttaaata aactacaaaa aggctatgaa gtgattacaa tcggtggact
    20401 ttatggaaca gtcgatgaag tagatacgga gaagggaaca atagttcttg acgtagatgg
    20461 agtttacttg acttttgaac tagctgctat caagacagta ttaccgctga aagaaacagc
    20521 ttcactagaa ggcgcaattg aaaaataaga cgggatcacg aactcccgtt tttctataaa
    20581 agaaaggaaa tgggatgaaa aaattagtct ttgtctgtct gggaaatatt tgccgtagcc
    20641 ctatggccga gtttgttatg aaatcaatga cagataacta cgaaatccaa agtcgagcaa
    20701 cttcctcttg ggaacatggc aatccgattc ataaggggac tcagggaatt tttcaacagt
    20761 atgagattcc ttatgacaag aacaagacat cgcttcagat tagtaaggaa gattttgaag
    20821 cctttgatta tattatcgga atggacgctt caaatatttc tgacttacgt cagatgtgtc
    20881 cagtagactg tcaagataag atttactcat tttcatctga aagtgttcca gacccttggt
    20941 atacaggaga ttttgaagaa acctatcgac gtgttcaaga gggctgtcaa gcttggttag
    21001 aacgtttaga aaaggagagt taaggtggaa aatcttacga atttttacga aaagtatcgt
    21061 gtctatctga ctcgtccacg tttagagctt ttggcagtag ttaccattgt tttctgtgct
    21121 gtactcgtct tttttctaaa tattccagga aaaggtgtct taaaactcga taatggaacg
    21181 attgtttatg atggcagtct tgtccgtggt aaaatgaatg gtcaaggtac cattaccttc
    21241 caaaatggag accaatatac aggtggcttc aacaatggag ccttcaacgg aaaaggtacc
    21301 tttcaatcta aagaaggctg gacctacgaa ggtgattttg taaatggtca ggctgaagga
    21361 aaagggaaac taacaacaga acaagaagtc gtttatgaag gaacttttaa acaaggcgtt
    21421 tttcaacaaa aataaagcct ccttatccaa aggaggtatt attagaacca caaggtaagc
    21481 gcttacctgt aaatcccttt ctttccaaat ccctcttcca agcaagtttg tgaaataaaa
    21541 aatatttgaa ataaatttca caaacttcaa agataaaacc tgataagaaa agaaaatgag
    21601 aaaagtttca caagagttta aaaattcttt gtgaaatgtt tatgaaactg tttacaaagt
    21661 tgaaataatg cgttataata aacttgtgaa aaaattaaca aaggatatcg ttccttgaaa
    21721 gctatggagg aaaatatggc tgataaaaaa actgtgacac cagaggaaaa gaaactcgtt
    21781 gctgaaaaac acgtagatga gttggttcaa aaagctctag ttgcccttga agaaatgcgt
    21841 aaattggatc aagagcaagt tgactacatc gttgccaaag catcagtagc agctttggat
    21901 gcccacggag aattggcttt acatgccttt gaagaaacag gacgtggtgt atttgaagac
    21961 aaagcaacta agaacttgtt tgcctgtgaa cacgtagtaa acaacatgcg ccacactaag
    22021 acagttggcg ttatcgaaga agacgatgta acaggattga ctcttattgc tgaaccagtt
    22081 ggtgttgttt gtggtattac tccaacaaca aacccaacat caacagcaat tttcaaatca
    22141 ttgatttcat tgaagacacg taacccaatc gtctttgcct tccatccatc agcacaagaa
    22201 tcatctgctc atgcagctcg tatcgtccgc gatgcagcta tcgcagctgg tgctcctgaa
    22261 aactgtgtgc aatggattac tcaaccatct atggaagcaa caagtgccct tatgaaccac
    22321 gaaggggttg cgacaatcct tgcaacaggt ggtaatgcca tggttaaggc ggcttattca
    22381 tgtggtaaac cagctcttgg ggtaggtgcc ggaaacgttc cagcttatgt tgaaaaatca
    22441 gcaaacattc gtcaagcagc acacgatatc gtcatgtcta aatcatttga taacggtatg
    22501 gtctgtgcat ctgaacaagc agttatcatt gataaagaaa tttacgatga atttgtagca
    22561 gagttcaaat cttaccacac ttactttgta aacaaaaaag aaaaagctct tcttgaagag
    22621 ttctgcttcg gcgtcaaagc aaacagcaaa aactgtgctg gtgcaaaatt gaacgctgac
    22681 atcgttggta aaccagcaac ttggattgca gaacaagcag gatttacagt tccagaagga
    22741 acaaacattc ttgctgcaga atgtaaagaa gttggcgaaa atgagccatt gactcgtgaa
    22801 aaattgtcac cagttattgc agttttgaaa tctgaaagcc gtgaagatgg tattactaag
    22861 gctcgtcaaa tggttgaatt taacggtctt ggacactcag cagctatcca cacagctgac
    22921 gaagaattga ctaaagaatt tggtaaagct gttaaagcta ttcgtgttat ctgtaactca
    22981 ccttctactt ttggtggtat cggggacgtt tacaatgcct tcttgccatc attgacactt
    23041 ggatgtggtt cttacggacg caactcagtt ggggataacg ttagtgccat taacctcttg
    23101 aatatcaaaa aagtcggaag acggagaaat aacatgcaat ggatgaaact tccttcaaaa
    23161 acatactttg aacgtgattc aattcaatac cttcaaaaat gtcgtgacgt tgaacgtgtc
    23221 atgatcgtta ctgaccatgc catggtagag cttggtttcc ttgatcgtat catcgaacaa
    23281 ctggaccttc gtcgcaataa ggttgtttac caaatctttg cggatgtaga accggatcca
    23341 gatatcacaa ctgtaaaccg tggtactgag attatgcgtg ccttcaaacc agataccatc
    23401 atcgcactcg gtggtgggtc tccaatggat gctgccaaag taatgtggct cttctacgag
    23461 caaccagaag tggacttccg tgaccttgtc caaaaattca tggatatccg taaacgtgcc
    23521 ttcaagttcc cattgcttgg taagaagact aaattcatcg cgattccaac tacatctggt
    23581 acaggatctg aagtaacatc atttgccgtt atctctgata aagcaaacaa ccgtaaatac
    23641 ccaatcgctg actactcatt gacaccaact gtggcaatcg tagatcctgc tttggtattg
    23701 acagttccag gatttgttgc tgctgatact ggtatggacg tattgactca cgcgacagaa
    23761 gcatacgtat cacaaatggc tagtgactac actgatggtt tagcacttca agccattaaa
    23821 ttggtctttg aaaatctcga aagctcagtt aagaatgcag acttccactc acgtgagaaa
    23881 atgcataacg cttcaacaat cgctggtatg gcctttgcca atgccttcct aggtatttct
    23941 cactcaatgg cccataagat tggtgcgcaa ttccacacaa tccacggtcg tacaaatgct
    24001 atcttgcttc catacgttat ccgttacaac ggtacacgtc cagctaagac agcaacatgg
    24061 cctaagtaca actactaccg tgcagatgaa aaataccaag atatcgcacg catgcttgga
    24121 cttccagctt ctactccaga agaaggggtt gaatcttacg caaaagctgt ctacgaactc
    24181 ggtgaacgta ttgggatcca aatgaatttt agagaccaag gaattgacga aaaagaatgg
    24241 aaagaacatt ctcgtgaatt agccttcctg gcttatgaag accaatgttc accagctaac
    24301 ccacgtcttc caatggtaga ccatatgcaa gaaatcatcg aagatgcata ctatggctac
    24361 aaagaaagac caggacgccg taaataattg tttatcagtc tagaagcaag acaaaaactc
    24421 aatttgaggg aaagatccag taatttttct atgataaaag gcatcctatc aaggtttttg
    24481 aacacctgat aggatgcctt tttatgatat tgaggccttt ttgccctttt tgaaaaacta
    24541 gaatagaaac aaaatatata atagattgaa actagagtag tacacatctg cttctaaaac
    24601 attgttagaa ttcgatttga ctgtcctgat caattt
//
LOCUS       DAVLDI010000034        24598 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLDI010000034 DAVLDI010000000
VERSION     DAVLDI010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24598
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.034"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(113..388)
                     /locus_tag="VXD01_001370"
     CDS             complement(113..388)
                     /locus_tag="VXD01_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV0601758.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(495..1334)
                     /locus_tag="VXD01_001371"
     CDS             complement(495..1334)
                     /locus_tag="VXD01_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0601759.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1476..2324
                     /locus_tag="VXD01_001372"
     CDS             1476..2324
                     /locus_tag="VXD01_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0601760.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2417..3334)
                     /locus_tag="VXD01_001373"
     CDS             complement(2417..3334)
                     /locus_tag="VXD01_001373"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV0601761.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3772..3977
                     /locus_tag="VXD01_001374"
                     /pseudo
     CDS             3772..3977
                     /locus_tag="VXD01_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4182..4475)
                     /gene="rpmA"
                     /locus_tag="VXD01_001375"
     CDS             complement(4182..4475)
                     /gene="rpmA"
                     /locus_tag="VXD01_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV0601762.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4492..4836)
                     /locus_tag="VXD01_001376"
     CDS             complement(4492..4836)
                     /locus_tag="VXD01_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV0601763.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4852..5166)
                     /gene="rplU"
                     /locus_tag="VXD01_001377"
     CDS             complement(4852..5166)
                     /gene="rplU"
                     /locus_tag="VXD01_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV0601764.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5202..5289)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5354..6052)
                     /locus_tag="VXD01_001378"
     CDS             complement(5354..6052)
                     /locus_tag="VXD01_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV0601765.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            6454..6753
                     /locus_tag="VXD01_001379"
     CDS             6454..6753
                     /locus_tag="VXD01_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV0601766.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            complement(7153..8127)
                     /gene="pta"
                     /locus_tag="VXD01_001380"
     CDS             complement(7153..8127)
                     /gene="pta"
                     /locus_tag="VXD01_001380"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV0601767.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(8171..9067)
                     /locus_tag="VXD01_001381"
     CDS             complement(8171..9067)
                     /locus_tag="VXD01_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0601768.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(9064..9882)
                     /locus_tag="VXD01_001382"
     CDS             complement(9064..9882)
                     /locus_tag="VXD01_001382"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV0601769.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(9866..10537)
                     /locus_tag="VXD01_001383"
     CDS             complement(9866..10537)
                     /locus_tag="VXD01_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV0601770.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            10665..11234
                     /locus_tag="VXD01_001384"
     CDS             10665..11234
                     /locus_tag="VXD01_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV0601771.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQIKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            11347..12306
                     /locus_tag="VXD01_001385"
     CDS             11347..12306
                     /locus_tag="VXD01_001385"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0601772.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            12316..13431
                     /locus_tag="VXD01_001386"
     CDS             12316..13431
                     /locus_tag="VXD01_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0601773.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            13436..13783
                     /locus_tag="VXD01_001387"
     CDS             13436..13783
                     /locus_tag="VXD01_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV0601774.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            13791..14006
                     /locus_tag="VXD01_001388"
     CDS             13791..14006
                     /locus_tag="VXD01_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0601775.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            14089..14730
                     /locus_tag="VXD01_001389"
     CDS             14089..14730
                     /locus_tag="VXD01_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV0601776.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            14748..15437
                     /locus_tag="VXD01_001390"
     CDS             14748..15437
                     /locus_tag="VXD01_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV0601777.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(15434..16114)
                     /gene="radC"
                     /locus_tag="VXD01_001391"
     CDS             complement(15434..16114)
                     /gene="radC"
                     /locus_tag="VXD01_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV0601778.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(16157..18448)
                     /gene="pcrA"
                     /locus_tag="VXD01_001392"
     CDS             complement(16157..18448)
                     /gene="pcrA"
                     /locus_tag="VXD01_001392"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV0601779.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVVRT
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNTQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(18639..19423)
                     /locus_tag="VXD01_001393"
                     /pseudo
     CDS             complement(18639..19423)
                     /locus_tag="VXD01_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(19802..20662)
                     /locus_tag="VXD01_001394"
     CDS             complement(19802..20662)
                     /locus_tag="VXD01_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV0601780.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(20678..21955)
                     /locus_tag="VXD01_001395"
     CDS             complement(20678..21955)
                     /locus_tag="VXD01_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0601781.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(21948..22499)
                     /locus_tag="VXD01_001396"
     CDS             complement(21948..22499)
                     /locus_tag="VXD01_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0601782.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(22515..23774)
                     /locus_tag="VXD01_001397"
     CDS             complement(22515..23774)
                     /locus_tag="VXD01_001397"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV0601783.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
BASE COUNT         7516 a         5284 c         4366 g         7432 t
ORIGIN      
        1 caatattttc ggaacattca actttttaac tctatttatt actagatttc ataattaaaa
       61 agcctactga ccaagctaga aagcttgata caataggctt tttaaagact gattatttaa
      121 cagcgtcttt aagagcttta ccagctttga atgctggtac tttagaagct gcaattgtca
      181 tttctttacc agtttgtggg ttgcgacctt tacgttctgc gcgctcacga acttcaaagt
      241 taccaaaacc gatcaactga actttttcac cagctgcaag atagtcagct actgctgcaa
      301 atacagcttc aactgctgct gctgagtctt tcttagtcaa ttctgtagct tctgctactt
      361 tagcgatcaa atcttgtttg tttgccatgt taatgattcc tccaaataat ttctaattaa
      421 caaatataat catatcctaa aatccctttt aggtcaagtt aaaaacgcta tttcttccca
      481 ttttatttat ttttttagga gtggtaacgt atcaaaatag cccaagcgtt ctcacccgtg
      541 tgagtttgaa taatggaacc cgtttccaaa acagaaattg gcttttcaac ataagcttgt
      601 aagctttctt tcatctcttt tgcccaatca tcactaccag aatatgaaat tccaatctct
      661 gctacagcac gttcagaaag cgatgttatc aactcatcta accatttttt aaatgtttta
      721 gttccacgac ctttaaccat tggctgcaat tcatggtctt tcatttgcat gacaacacgg
      781 atattgagaa gagagctcaa caagccagtt acacggctaa ttcgtccacc tttgacaaga
      841 ttttccaaag ttgaaacacc aatataaagc tctgtatggt ttttaacctc ttctacatga
      901 cataaaattg cctccatatc tttaccttct tgagctaact tcgcagcctc aacaacttgg
      961 aatttcaggg cttggtcagt gaaggaacta tcaacaacag tcacatctgc agtagatagg
     1021 ctagcacctt ggcgtgctgc ttctaccgta cccgaaagag catgggacat atgaatagca
     1081 agaatctggc caccatcttt gcataggtct tcaaaaatct cagcaaagac acctacaggt
     1141 ggctgacttg ttttcggaag attcttactt tcttgcatca actgaagaaa tttaccttct
     1201 tctttcaaat ccgcatcaga ataaacaaca ttatcaatca ttacagataa tggaacaatt
     1261 gtaatatcta attgctttac tagttcaggt tcaatagtaa cagatgaatc ggttacaatc
     1321 ttaatttttg tcatagtatc aatctttcta ttttaggatt cagattggtt tccttacttc
     1381 taattatatc aaaaaaaaga ttaaaaatcc taatggagtc aatcaaattt tccgtaaaat
     1441 ttgatataat caacttataa gaaaagaggt gtcctatgat taaaaaaatt taccccattt
     1501 ttaccatttt actaggtgct gctatttatg cttttggact gacttatttt gtagttcccc
     1561 atcatctctt tgaaggaggg gcgacaggta ttaccctcat cacattttat ctttttaaaa
     1621 tccctgtttc cctcatgaac ctgctgatta atattcccct tttcatccta gcttggaaga
     1681 tctttggagc caaatccctc tattctagtt tactaggaac cttagctttg tccggctggt
     1741 tagctttttt tgagcatatt ccccttcata ttgatcttca aggtgattta ctaatcacag
     1801 cccttatagc gggaatccta ttgggaattg gccttggaat tatttttaat gctggaggta
     1861 caactggcgg aactgatatt ctagctcgta ttctcaacaa atacactcat atatccatag
     1921 gaaaactgct ctttatctta gatttttgta ttctcatgtt gattctccta atcttcaagg
     1981 atttgagatt ggtttcctac acgcttttgt ttgattttat tgtttctcgt gttattgatt
     2041 tgattggtga aggaggatat gccggcaaag gctttatgat tatcacaaaa cgtcctgacc
     2101 aacttgctaa ggcgattaat gatgacctcg gaagaggtgt tacttttatt tctggtcaag
     2161 gctactatag taaagaaaat ttgaaaatca tctactgtat tgtcggaaga aatgaaattg
     2221 tgaaaacgaa ggaaatgatt catcgaatcg atcctcaagc ctttataact attacagaag
     2281 cccatgaaat cctaggagaa ggcttcacct ttgaaaaaga ataaaaagag gtaatgtcgt
     2341 gacctcaaaa gttagactaa atcatctatc ttttgggtta cagacaacct cttttttatt
     2401 ttatttactc aagctcttaa gaccaattcc gagttacttc ttcatcagcc tttaactgat
     2461 ccactaattg gtcaactgag tcaaatttgg tcatatcacg aatgcgatca agccaataaa
     2521 ccatgacggt ttccccataa atatcttgat taaaatcaaa aatattgact tcaaaacgtg
     2581 cttcttctcc atcaaaggtc acatttttcc cgacactagc catagcacga tacttctgtc
     2641 tttgaatctc aacatcaacg acataaacgc catctgctgg catataagta cggtctaaaa
     2701 gcactaaatt cgctgtcgga taaccaattg tacgaccacg agcattacca tgaaccacca
     2761 tacctcttga tggaagcggt gcccccaaaa gttttcctgc ttctttcaca tttccatcta
     2821 aaatagcttg acggatacga gttgaactaa tctttccttt ctcatcttct acaggtggaa
     2881 caatgataac ttctccatca aagtaatcct ttaaatcttc tgctgttttt ttgtcagaac
     2941 caaatgtata atcaaaacct gcaacaataa ttttggcatt catagccttg atataagttg
     3001 caaaaaattc ttgtgcagtg agactagcga attgactact aaaatcaagg agatataatt
     3061 cttctacacc ttcgcgcttt aattttcttt cacgttcagc agggttcaaa atatgcaaaa
     3121 acaaatctgg atgataaggc tctaaagcga tctttggaga ttcattaaag gtcataacga
     3181 cgataggtaa taaatccttt ctcgcagcct tgttggcaac acgaaataat tcttgatgcc
     3241 ccttatgtat gccatcaaaa tagccgagaa caacgactga atcagatggt gtgccaatat
     3301 ctttttggtt ttttatagga atagtaataa tcataaaata attatatcat agcgatagct
     3361 atttctggaa cagaaaatct gaaatgttgt ttttttcaca tgaagtgtac ctgttttcaa
     3421 aaagcacttt attctatcgt tgcttaacta tgaactttgc aatattcttc tcaaaaactt
     3481 gtaggacatc ttcaaaattt tgcaaggagt gattagactt gttcggtaac cataaagtgt
     3541 catactatgc ttatgtatga aaaagcaatg caactaactc ctgagaactt taaattacta
     3601 attggtgccg aaaaggtaga atttagaatc gaggtacacc tatggctgta aaatttacaa
     3661 aatgagacaa cttgggcaag atgtttgaag aatttcctaa actccctgat ttgaagcaag
     3721 tcactttccc tgatgacaaa gaaaaaagcc aaaacagcaa agaaaaacta gatgactgct
     3781 ttccaacaac tcccatctag tgtgcttcag actgggctat ttttctctcc atctgttagc
     3841 ttggattctc agacagtttc agctaaagaa tatcttttcc cttatcagaa ggaacggctc
     3901 aaaccattca gacaagtgaa gggacgacaa gccaatattt gaaaccagat agcagttctt
     3961 atagtcaatt gaaataaaat ctgaagaaat cgagtaggaa actcatatca atttttaaca
     4021 gtgttctatt ccagattcaa tccactatac atattaaaaa gtatgggtac caaaacaaaa
     4081 aaacaggctc tccgaaaact cggaaagcct tattttaagc tgtttctagc ttcctcacct
     4141 ttacatttca aggttcggga taaaaggttc aatggacctt tttatttagc gattgggtaa
     4201 acagaaactt gttttttatc gcgtccttta cgttcaaagc gtactacgcc ttcaacttta
     4261 gcgaacaaag tatcgtctcc accacgacca acgtttacac ctggatagat gtgtgtacca
     4321 cgttgacggt aaaggattga tccacctgtt acagtttgtc cgtcagctgc tttagctcca
     4381 agacgttttg cttgtgaatc acgtccgttt gatgtagaac ctccaccttt tttgtgggcg
     4441 aaaagttgca agttgttaag agtcattttt aacataatgt tttcctccgt gttagttttc
     4501 tgtgataact ctggtttgga cgaactcaga atagttctcc gataagtttg ccatacctaa
     4561 gaaaaatgat tcaaagaata actgggtcat ttctctctgg tgtgaaggaa gatcttttgg
     4621 tatttcaacc atcagatagc caccttcatc ttcgtttaat tctaggattg gttcatagcc
     4681 tgcaaatttc tcaatagaat tgataaagtt aatggcaagc gtagaaaccg atgcacacac
     4741 gacatctaag ccgtattcgc cactctcggc gtgtccagta atttccgcac tcctcagctc
     4801 gccatcttcg gctctctcaa agactgcctg tatcatgtgt tctccttaaa attaagcgtt
     4861 gattgcgttg atgacaactt ttgtatatgg ttgacggtga ccttgtttac ggtggctacc
     4921 ttttttaggt ttgtacttgt aagtaaccac tttcttttgt tttccttgtt tttcaacagt
     4981 tccaactaca gtagctccag caacaagtgg agttccgaca acagtatttt caccaccaac
     5041 aagaacaact tcgttaaaag taacttcttg accagcttca acgttcaatt tttcaacgta
     5101 aactgcttga ccaacttcaa ctttaacttg ttttccgcca gttttgataa ttgcgtatgt
     5161 gctcattatg cacctcctat gatttttatg ggtttccccg attttttgtg aagactcgcc
     5221 tagcatcgtg ggacgaacca cttaaacttg aataatcaag caacgatgtt cgtgcggttg
     5281 cacaggatcg tgcatagtca actcttcaag tatagcatat ctcctatttt cttacaagta
     5341 ataacaccta aaatcaagct ttttctttta cttttttctg ccaagaggca aaaagcatgc
     5401 tgaggtaaaa aacgctcatc ataataggaa caccaagaat ggtcttttca tgatagaaaa
     5461 tcgtcaaata ggctgaaaag acaacgccaa ggacaaaact actaagcagg ctaacaaata
     5521 tgaatccttc acgcaaaaaa ggagtgtgct tggttcggaa ataatctcca aaagccagca
     5581 tggtccgttt gatattccct gtcataaaag cgttattata ggcaataccc gacacttctc
     5641 caaaagcagt tgtcaccagt cccatacaga aggccaaggg cggcactaga tagatattat
     5701 ccacagtttg cggcacaaaa gcaataatga ttgataagat tgccaaggga atcaaggaca
     5761 gaataggttt tttcacaatt ctcaattttt ccttataaat cgttaataaa aagactccca
     5821 tcataaacgc tagcaaggtg agaaccttgt ccctaacatc cgaaacatta tttttaatta
     5881 attctactga aagaaagaca acatttccag tttgtccagc tacaagggta ttcccgcgaa
     5941 caataaaagt gtaagcatcc acatatccag cacaaaacgt caaaaaaagt gctaaccttt
     6001 tagactgacg tgatattttt cttataggta ataacctcat tttccctccc attgtatttt
     6061 ctcttagaaa tattgtacca tttctttcta aaaaatcgta gactaccatt tagattttac
     6121 tattagcata aaaataataa tagacaacta tttatccaaa aatagataga ggtaacatgt
     6181 ttgcaaacaa agcatacgaa tctttagtaa aatcatttcc atgaaactag aatagagccc
     6241 ctcttagcaa aaatcattat tttaatttat ttctaatcac tccttgacat aaataactct
     6301 caccaataaa agactatgtc ttaaaaaaat ggtataataa aatcaatact tgggcttgat
     6361 ggctatgcta ctaataacaa ttaggagaga aaatcaggca cttgttaaca acaaggatta
     6421 tccccttgag atgaaaggaa ctttagaaat cttatgatga acatgcaaaa catgatgcgt
     6481 caagcacaaa aacttcaaaa acaaatggaa caaagccaag ctgaacttgc tgctatgcaa
     6541 tttgttggca aatctgctca agatcttgtc caagcgacct taactggcga taagaaagtt
     6601 gtcagcattg atttcaatcc agctgtcgtt gacccagagg accttgagac tctttctgat
     6661 atgaccgttc aagccatcaa ctctgctctt gaacaaatcg atgaaactac caagaaaaaa
     6721 ctgggtgctt tcgctgggaa attacctttc taaaaacaag gagctagaac aatgcttgtc
     6781 gataacaaag gctaagaaag gtgcaaaaat gactctataa tatttgtagt gggtaaatcc
     6841 actatagata ttatggagcc tattttattg tagaaaacgc ataatagcag gtgtcaagac
     6901 acttaatatt atgcgttttc tcatgaaaaa attctctttt catactcatt taaaatcaaa
     6961 aagggaaatt atcgttttac ggacatacat attacagatt tctataggtc gtgtatagac
     7021 aggatatcat cgcttggaag ttttcctttt tgacaccaat cagtaattta gttctcagga
     7081 attaatggca gtgcttttcg tacatagttt cataactaca gtatagcata gtatatcgct
     7141 ttatagtttt cactattgat gaactgcttg agctgctgtg atgagggtca acttgtaaac
     7201 atcatctgca ttacatccac gagaaagatc attaactggc ttgtttaaac cttgcaaaac
     7261 aggtcctaca gccgcaaagc cacccaggcg ttcagccatc ttgtaaccga tatttcctgc
     7321 ctcgatacct gggaagatga agacatttgc ttgaccagct accgtacttc caggagcttt
     7381 cagagctgca gtttcaggaa caaaggctgc atcaaattgc aactcaccat cgatttcaag
     7441 gtcaggacgc aagtcgtgag caattttagt tgcttcaacg accttatcaa cgctttcacc
     7501 aaaccctgaa cctttagtag aatagctcaa catggcaatt ttaggttcga tgccaaacat
     7561 cttagctgtg attgctgagt tgatggcaat ttcagccaag gcttctgcat ctggattgat
     7621 gttaatggca cagtctccaa ataggtaacg ttccgtacca cgaaccatga ggaaggctcc
     7681 tgaagtacga gttacatttg gacgagtttt gatgatttgt agagctggac gaactgttga
     7741 agctgttgag tgaatcgctc ctgacaccat tccatcaacc aagcccaagt aaaccaacat
     7801 cacaccaaag tagttgacat cttcaaccaa aaccttgcgt acatcttctt cagtcatttt
     7861 gcccttgcga cgctccacca aggcagaaac catttcttca aattgaggat aatgttgagg
     7921 gtcgatgacc tcataaccat ccatgatccc ttcaatttca agataaattt taattttttc
     7981 aggatttcct aacaaaacag gaatcacttc tgtttctttt accaaacgtt tagtcgcttg
     8041 aagaatacgt ggctcttccc cttcagggag aacgatacga gcatttttac caacaaggtt
     8101 ggctttgaga ctttcaaaaa cttccatgag ttttctcctt taagataata attatactct
     8161 gagacagttt ttatagagta ttagttgata actgggtaat aaggttactg aaatcatccg
     8221 gcaagggact ttctaactgc aagtcttgct ctaaaaatgg atgataaaag gataggtaat
     8281 ggcaatgcag agcctgacgt tgaataccat cttccagact accaccatac aaatcatctc
     8341 ccagcaaagg aaaaccgata tgagaaaaat ggactcggat ttgatgggtt cgaccagtgt
     8401 gcaggtgaat atagaccaag tgaatatttc cataagaagc tacaatcttg tatgaagtat
     8461 gggcatactt tccgccttta gccactcgtc tggtaataat ggaatcttca tcacgcgcaa
     8521 tcggagcaat aatttcccct tctggctcca aatgtccatc tcccttaacc aaagcaaagt
     8581 agcgtttctc gatagatttc ttctgcaact gcttgtctaa tcgtgcatgg gcataaccgt
     8641 gcttggcaaa gagcatcaag ccagaagtgt ccctatctag tctggtaaca atgtgaacct
     8701 gctgattttc ataattttgc ttgacatagt aacccttgat aaaattggca atggtattag
     8761 agtgattaac actaggaata gaagccactc catagggttt attcaagact agaaagtggt
     8821 catcctcata gagaatatct aatggaagct caatagcctc caaggtttca aagcctttct
     8881 cagcgggaat gtcaatggta acgtagtctc caacgtccaa tagatacgtt gcattttgcg
     8941 gttgattatt gaccagaata gctccacctc gaaacttaat cttggccagc aatcccttag
     9001 aaacctcgtg cttttttaag aaggtcttaa ccttgacatg ttcatctgcg ataaattcaa
     9061 acctcattca tccacctcac cgataaaggc atccttaaca cggttccaga aactggtatg
     9121 gctaggagtc gcgacaaagt gaatcttatg atgggcgatt tgatactcaa tacgctcaat
     9181 attacggaaa gaataaacgc tattgtcaac cgaaatagta tgataatcgt ttcttgttgg
     9241 aataagttca atcttatcct tcttaggcac aataatggaa gagcccagtg ttcgatagac
     9301 acgattatta aggctggcaa tttccgttaa ttgcaaagct tcaatggtag ggtgtaaaac
     9361 agcaccgcca agagacttgt tataggcagt actaccagtc ggtgtcgaaa ctgttagccc
     9421 gtctccacga aaacgttcaa agggaacacc atttattaca atatctgcca ccatggttcg
     9481 atcagacctg cggatgctgg cttcgttgag tgctctgaaa atcttaactt caccattttc
     9541 aagaaagacc ttcacattca gaacagggta agaaaccctt gccccagtat ctagctgcaa
     9601 attagtcact agcttgtcca actcaaaatc acgataatct gtatagaagc ccaaatgtcc
     9661 agtgtgaaga ccgataaagc ggaccttctc aagctgattt tcgtacttat gaaaggccga
     9721 caagagcata ccatccccgc caatggaaat gacaatatcc ggattggtat cattgagtat
     9781 aaactgattt ctcttcaaac gatctcgcaa ttcatacaaa accctttgac tctgcggttt
     9841 tctattggct atcagatcaa ttcgtttacc tgtattcttc atctgtatcg tcactgtttc
     9901 ctacaccgtc atttaatttt ctactcaaag gatcaaaaag tgcctgggct tcttggatat
     9961 catcacgaat ttcacccatt tcttcatcca actgatgggc gattctagct gtaatttcca
    10021 gtcgcttctt aatctcatct gggaaatccc cttggtactt gtagttgaga gaatgttcta
    10081 tcgttgccca gaaattcatg gccaaagtac gaatttgaat ttctgccaaa atagtcttag
    10141 ctccattgat ggtatcaacc gtatattcta ctaccacatg ataggaacga tagcctgatg
    10201 cttttctatg agtaatgtaa tctcgctcct gtatgattcg catatcctga cgcttgtgca
    10261 aaatatccac tacttccttg acgtcatcta caaactgaac catcacacgt aagccagcaa
    10321 tatcctgcaa atcgtgttcc aaggtcgcat aagtaatgcc acgacgagcc attttttctt
    10381 tgatgctctc aattggcttg actcgaccgg tcacaaactc aattggagaa tgcttatttt
    10441 gcttacgata ttgcttacga ataccacgaa gtttaatctt taactcacca acagcttgaa
    10501 tgtaaggatc tagaaattct tcccattcta aggtcatata ttctcccttg ttctcatatt
    10561 atccgtcaaa aatatctttg attttttctc cagattcata tacaataaat acaatgctta
    10621 ttataccata aatccgcttt caacgataaa aaaaggtaag aaaaatgaaa catttagaaa
    10681 ttgaattgaa aacactattg aaaaaagatg aatacaatcg tctaaaagac cagttcacag
    10741 gtgtcactcc tgttcttcaa acaaattact acatcgacac gcctgatttt gaactgcgag
    10801 aaaagaaagt cgctatgcgc attcgaacct ttgaagactg ggctgagttg acactcaaag
    10861 tcccgcagag tgttggaaac atggaataca accaaaaatt gcaactaaaa gatgctgaga
    10921 actatctgag taaggaagaa cttcctcaag ggctagtact ggatgaattg gcgaaacatg
    10981 gtatccaaat taagaactgg caggttcttg gttgtctaac aacgcttcgc tatgaaatga
    11041 aaacagctat tggtctcatg gcactggatc agagccgata ctttgatatg acagattacg
    11101 aattggagct tgaagtggaa aatcatgagc aaggcaaaca ggatttccga caatttttag
    11161 agaaaaatca gatttcctac caaaaagctc cttcaaaatt ggttcgattt gtcaaaagta
    11221 tgaaaaatag ctgaaataat ctccattttt tggtaaaata gaaaagataa aaatacacaa
    11281 actccagttc atatatgtaa ggtaaatata actaggattt ataaagttta cagaggacgg
    11341 tctataatgt cagatagaaa aaacatgaaa cttttcgcac tcaactctaa ccaagagatt
    11401 gcacagaaaa ttgcccaagc tgttggtgtc ccacttggaa aactatcatc acgtcaattt
    11461 tcagacggag aaatccaagt aaatatcgaa gaaagtgtcc gtggttatga tgtttacatc
    11521 atccaatcaa caagtttccc tgtcaacaac cacctaatgg aattgttaat catggtcgat
    11581 gcttgtgtgc gtgcaagtgc ccacagtatc aacgttgtcc ttccatattt tggctatgca
    11641 cgtcaagacc gcattgcttg tcctcgtgag ccacttacag caaaactagt tgccaatatg
    11701 ctggttaagg ctggagttga tcgtatcctg actcttgatt tgcatgccgt tcaggttcaa
    11761 ggtttctttg atattccagt ggataatctt ttcactgttc ccctattcgc aaaacattac
    11821 tgcgataaag gattgcttgg ttcagatgtt gttgtcgtta gccctaaaaa ttcaggtgtc
    11881 aaacgtgcgc gtagcctggc tgaatatctt gatgctccta tcgccattat cgactaccct
    11941 caagacgatg caactcgtaa cgaaggttat attattggtg atgttgaagg taagaaagct
    12001 atcttgattg atgatatttt aaatacagga cgtaccttct ctgaagcttc taaaatcgtt
    12061 gaacgtgaag gagctacaga aatttatgct gtttctagcc acggtctctt cgtcgaggga
    12121 gctgctgagc ttcttgacaa tactaatatt aaagaaattc ttgtgactga ttcagtagca
    12181 acaaaagaaa aaactcctaa aaatgtatgc tacatcactg ctagtgagtt aattggtgat
    12241 gctatcgtcc gtattcacga aagaaaacca gtcagcccac tctttgccta caataaaaag
    12301 aaataaggtg attctttgat ttatttggac aatgctgcaa cgactcctat gtcagcagtt
    12361 gctatttcag ctatgaccaa ggttatgcaa gaaacccacg gaaatccttc tagtattcat
    12421 ggtcatggtc gtcaagctgg caaactcttg cgagaagccc gtcaggaact agcccagtta
    12481 ctaaggacaa aacctcaaca tatctttttc acttctggtg ggactgaagg caataatact
    12541 accatcattg gctactgtct tcgtcaccaa gaacaaggaa aacatatcat cacaactgcc
    12601 atcgagcacc atgctgtcct tgaaacaatt gattacttgg ttcaacactt tgggtttgaa
    12661 gcaaccatta tccagccaga aaatcaagaa atcacagccc agcaaattca aaaggcttta
    12721 cgtgacgata cgattttggt ttctaccatg tttgccaata atgagacagg aaacctactg
    12781 cccatcgctg aaattggcca aatactcaag caacaccctg ctgcctatca tgttgatgca
    12841 gttcaggcta ttggtaaaat cccaattcat tcagaagaat tgggcattga ttttctcact
    12901 gcttctgccc acaaattcca tggtcctaag ggaatcggtt ttctctacgc atctagcatg
    12961 gactttgatt cctatctaca tggcggagac caggaacaga aaaaacgtgc aggaactgaa
    13021 aatctgcctg ctatcgtagg catggttgca gccctaaaag aagacctaga aaaacaagaa
    13081 gaacattttc aacatgtaca aaatctagaa actgcctttc tggcagagct ggagggcatt
    13141 cagtattact tgaatagagg aaaacatcat ctcccttatg ttctcaatat tggatttcct
    13201 ggtcagaaaa atgacctctt actccttcgg ctagatttag ctggaatttc aatctctact
    13261 ggctcagcct gtactgcagg cgttgtccaa tccagccatg ttcttgaagc catgtatggc
    13321 gcaaattcag aacgcttgaa ggaatccctt cgcatcagtt tgtcgccaca aaataccgtt
    13381 gaagacctac aaaccctcgc aaaaacctta aaagaaatta tcggaggtta gccatatggc
    13441 atttgaaaaa atcattcagt taaaaaattg tcgttacgat tacactctta gcccttctgt
    13501 taaaaaattc accctcaaag ataacacctt ttttgaaact aaggttggta actatgaact
    13561 gactcgcctt ttggaaaaag tgccaaacag cggtgaaggc ttccaactca aaatcatcat
    13621 taacaaggaa cttacagggg ctaaaatcaa tatcactgac aagtttggcc ttcgtctagt
    13681 tgatattttc aaatcagaag accaccatat tcatcaggaa aaattctact tcctcatgga
    13741 tagcttggta gaacgtggtg tctttacaaa atcggaaaga tagagccaaa atgtttgaac
    13801 tgacctataa ggactgctat catgtagagc gtactctcaa gtatgaggat catgaggctc
    13861 tcatgttgac tttgtcagga tgtgtaacct taccagatac actttatgtg acttctctga
    13921 cttttagggg ccaaaaagtt tatcagggtc tggtcggaga cctctaccgt tttctatctc
    13981 atgcagattt tttacatcaa aactaagatt tttcttagtt ttttcttatt tttgttgatt
    14041 ttttcacaat gtttctataa aatagaagaa tagaaaggtt gtgattttgt gaaagataaa
    14101 cagtttgcta ttccaaaagc tacagcaaaa agactctctc tctactatcg aatttttaag
    14161 agatttcatg cagaaaagat tgaacgtgcc aactctaagc aaattgcaga ggctatcggt
    14221 attgattcag cgaccgtacg tcgtgatttt tcctattttg gtgaacttgg tcgtcgtggt
    14281 tttggctatg atgtcaaaaa actaatgaca ttttttgccg atttgctcaa tgacaactct
    14341 attaccaatg tcatgctggt tggtattgga aatatgggcc atgcccttct ccactaccgc
    14401 ttccacgaac gtaacaagat gaagattatc atggcctttg acctagacga ccatcctgaa
    14461 gtcggtaccc aaactcctga cgggattccc atttacggga tttctcagat caaggataaa
    14521 atcaaggatg ctgatgtgaa gactgctatc ctaactgttc ccagcgtcaa gtcacaagag
    14581 gttgctaatc tcttggttga tgctggtgtg aaaggaattc tcagtttttc accagtccat
    14641 ctgcatttac caaaagacgt ggtcgttcag tatgtcgatt tgacaagtga actccaaacc
    14701 ctcctctact tcatgcgaaa agaggattag aaagcgaaaa tcattttatg aaaaaaccag
    14761 ttattgggat tacaggaaac gaaaaagctc atccagatga tgacatcatg atgagctacg
    14821 cagcaaaagg ctttgttgaa ggcgttaaag atgctggagg gattcccatc atcctaccga
    14881 ttggtgatca agaaatggcc tgccactata tcagtttgat tgacaagctc atcttgacag
    14941 gtgggcaaaa tgtcgatcca aaattctatg gcgaacccaa aaccattgat agcgatgact
    15001 atcaccttca aagagatatc ttcgaactgg ccctcatcaa ggaagctatt aaacagaaaa
    15061 agcccatttt ctctgtctgc cgtggtaccc aactctttaa cgttgccatg ggtggaactt
    15121 tgtaccaaga tatcgaagac cattggcagg attcttctgt tgagtacaca actcaacgct
    15181 tggtaacaga accagatacc gttctccaag aaatctatgg agaaatctct catatcaact
    15241 ccttccacca ccagagcatc aaggacttag caccaaattt aaaagttgtg gctcatgatc
    15301 ctaaagatgg tatcattgag gctgtcatga gtacggatga tgtcgccttt ctcggtgtcc
    15361 aatggcatcc agaacttctt tttgaaaatc gtcccaaaga taaaaaactc tttgactatg
    15421 tcgttaatga actttagatt aaatctgtct tttcacgata actaaagtaa ttagaatgag
    15481 agacaatcaa atggtccaag agaacaatcc ccatcagttc gcaggcttct ttaacaagtt
    15541 tagtgacatg atcatcattt tggctaggcg ctaccgctcc tgaaggatga ttgtggacca
    15601 agataagaga agtcgccata tgcttgattg catagtgaag aatctctcgc ggttcagcga
    15661 tactacgagt tacagaaccg ataaaaatgg tctgctgatg gatgatttga ttttgagtat
    15721 tgagatagag tgccaccagg tgctcttgtt ttttatcccc taattcctgc tgcatcttct
    15781 tggccaactt ttgactgctg agaatacttt ccatttcaag agtctcgtgt ttgtgaatac
    15841 gatgccccag ttcaatcata gcttgtaatt ctatggcctt aacacgccca ataccagaca
    15901 aactctgcaa ttcctgcagg gtcatttttt tcaaatccgt taggcttgaa agattgttca
    15961 agactttttg ggcaatttca aaaacgctag cttgacgtgt tcctgtcctg agtaaaatag
    16021 ctagcaactc ttggttacta agcgcttcaa ctccttcctt ggccagcctt tctcttggta
    16081 atagtgaatc ttcttggaat gaaatactgt acataaaaat cctcctcact ttattattcg
    16141 tgagaaggat ggaaaattag atttttttct caattggagc cacactggct aaaagttttt
    16201 tcaaacctac ttctgggaaa ttgattttca attcctgcct agcaccgcta cctgaaactt
    16261 ccagaacagt tccctctccc catttcttgt ggagagcaat gtcaccaatg gaccaatttg
    16321 cctcgctaga tgctggtttt gcgccagctg taaattgacc aaatggaaga ccgcttgact
    16381 ggattgattt tggggcagca ccgcgtttac ggtcttgaag agcctgagcc aaactcatac
    16441 cttgaccaaa ggaaatacta ccactgctat atgatgcctt aaagcttgta tttgcaggac
    16501 gagccagacc ttgatactca agcaagtctg aactgatttc gttaataaaa cgagtcggac
    16561 ggttataatt ggtacgacca aaaagcaagc gtgagttggc attggtcaga tagagaattt
    16621 tctctgcacg cgtgatacct acataggcta gacggcgctc ttcttctaat tcatctggat
    16681 cttcagtcgc acgactaagt ggaaagacat tttcttccat cccaatcaaa aagacaactg
    16741 gaaattcgag acctttggca gcatgcaggg tcatcaaggt cacttctgat gtttcctgac
    16801 tacctgaatc tgtgtcggca atcaaagcca agtcatttaa gaaacgactc agtttgtcca
    16861 gaccagtttc ctcttctgtc acatcagtgg tgtcatcaaa gttcttcgta acagaaagaa
    16921 actcttcgat attttcaacc cttgccttgc tttctagagt cgcttgggtg ttaagaatat
    16981 cgacataacc tgttttttct aggacggact caaccaactc tgtaatgctt aagtggtcta
    17041 gctgctcccg caaatcaagc atcatattgg caaaatccca gatagattgg gctgccttac
    17101 ccttgatacc agacaacata atattagcag aagcatccag catagacata ttttgcaaat
    17161 ttgcaaaatc acggattttc tcaactgtac ctagaccaat tccacgttta ggctcgttga
    17221 taatacgctc aaaactaata ttgtcactca aattagcaat aaggttgaga taagcaataa
    17281 tatcgcgaat ttccttacgg ctgtagaatt tggttccacc aaccatggta taaggaatgt
    17341 tagacttgag cagggcttcc tcaattgtac gggactgggc attagtccga tagagaactg
    17401 caaaatcctt atgaaggaag ttttgactgc gactaagttc atcgatggtt ctgactacaa
    17461 atacagcctc atccagctca tcatcggcac gatagtaaac gatttgctcc ccatcagcgt
    17521 tttgagtcca gagattttta ggacggcgat ttttattatt tttaataacc tcgttggccg
    17581 cttggagaat ggttttggtt gagcggtaat tttcctccaa caaaacaacc ttggctttgg
    17641 ggtaatcctt ttcaaagtcc aagatattct gcatatcagc accacgccaa ccgtagatag
    17701 actggtccgc atccccaacc acacagatat ttttaaaacg ggaagccaag agtttgacca
    17761 attggtactg agcgtggttg gtatcttggt actcatcaac gtggatgtat tggaattttt
    17821 gctggtagta ggtcaaaaca tcaggatttt gatcaaagag acgcaaggtc agcataatca
    17881 aatcatcaaa gtcaacggat tcagactgac gaagttcttt ttgataggtt gtataacact
    17941 gggccacaat ttgcgtatac atatcgccag cttgggcagc ataagcaaca tcatcaatca
    18001 aatcattctt agcattggaa atggtcccca aaatagttcg ttcattccat tttttaggat
    18061 ccaagttcaa ctgtttgaga atacgtttca tgagcgttcg ctgttcacca ggatccacaa
    18121 ttgtaaaatt acgattgtag ccaatatggt ccgcatcgcg acgcaaaata cgcacacaca
    18181 tggagtggaa ggtcgcaatc agacagtcct gagtagctgg attgaggcta taagcacgct
    18241 ctttcatctc acgcgcagcc ttgttggtaa aggtaatggc caagatattc caaggattga
    18301 ccagcttttc atcaatcaaa taagcgatac ggtgggttaa aacacgagtc tttccagaac
    18361 cagcccctgc catgattagc aagggacctt ctgtcgtttg caccgcctca gcctgacggt
    18421 cattcattcc atttaataat gcgttcatct tctcttcctt actcttgaag tcaatatttc
    18481 tattatatca gaaatcaggg aaaatagaaa ctttacgggg agtagcaaaa tatagtggat
    18541 tgaaactaga atactacact gtgggtttct aaaacactcg acttttcact caattttttc
    18601 ataaactagc tcaatacctc aatagacttc ctgcaaaact agaatcctag ttcatgattg
    18661 ataataccag caatcaaatt cattcgtaat ccgaagcatt tacgatgatt tcgataggtt
    18721 gttgaaaaca ttttaaacgt ttctactttg gcaaagatgt tctcaaccat gcttctctcc
    18781 ttagatagcg catggttata ggctttatct tcagctatta gcgacttgag tttgctggat
    18841 ttacgtggag tttgtgcttg aggatatatc ttcatgagcc cttgataacc actgtcagcc
    18901 aagattttac cagcttgtcc gatatttccg cgactcattt tgaacaactt catatcatga
    18961 caatagaaac aattctccct tgacttgtga caatcgcttg agccttcata gcatgaaatt
    19021 tctttttacc agaatcattc gctaattgtt tttttagggc gattgatttg tacttccgtc
    19081 gcatcaatca ttaccgtgtc ctcagaactg agaggagctc ttgaaatcgt aaaaccgctt
    19141 tgaacaagag ttacttcaac ccattggctc cgacggagta agttgctttc gtgaatacca
    19201 aaatcagccg caatttgttc ataagtgcga tattctcgca catattgaag agtggccata
    19261 agaaggtctt ccaggcttaa tttaggtttt cgtccacctt ttgcgtgttt aagttgataa
    19321 gctgttttaa tacagctaac atctcttcaa aagtggtacg ctgaacacca acaagacgct
    19381 taaatcgtgc atcagttagt tgtttacttg cttcatcatt catagaacta ctataccata
    19441 ttttgtttcg caggaagtct aatctaaaaa aggtaaattt aagattggca atacgaacat
    19501 taaacagaat tccatttctc tttttagaat caaaacgaca atattgtgga atctctacag
    19561 gaacaataga ctgcgacact aaaatatcct cccttagttt tactttacta atagtatata
    19621 ggaggagagc cctgaatcct agaccctttg ttatgatgcg cttacaaaca gagttggaaa
    19681 aaatcttaaa agcagaaaaa cgcatgatat cagcccctaa cacttgatac aatgcgtttt
    19741 attatgaaaa gatctactgg attttttcat aataaacttc cagtagtctt ttcacttttt
    19801 attaataagt tccttcttca ccttggctag tcaagataac aggtccatct ttcgtaatga
    19861 caaattggtg ttcatactga catgacaatc caccgtcaat ggtcttatgc gcccaaccag
    19921 ttttcatatc tgtatcaatt tcccaatcgc ctgtattgat cattggttca atggttaaga
    19981 ccattccttc acgaagacgg agtccacgac ctgcaatacc atagttagga accattggtt
    20041 cttcgtgcat agttgggcca acaccatgac caaccaaatc acgcactaca ccgtaaccac
    20101 gactttcagc gtattcttga atagccgcac cgatatcacc gatacgattt ccaacaacag
    20161 cttgctcaat acccttgtac atagcttctt tggttacatc catcaagttt ttgacttctt
    20221 cggacggtgt accaacagca taagcccaac atgagtctgc taaaccacca gaatagctct
    20281 gagtgtattt tttcatttgt tcaacattgt tgaagtttaa ttttgagaca ttcaggtcag
    20341 atttagcaat gggacctccc aaaaccatat caactttgag caaatcacca tctttcaaga
    20401 tataatgacg agggaaagcg tgagccactt catcgttaag agagcaacag gtagcataag
    20461 gatagtccat catggcaccg tcaaccccaa tctgaagtgg aaggaaattt tcttctttac
    20521 aacgacggcg gacatattct tcaacttccc acatatctac gcctggctta atcaaatcac
    20581 gtaagcctat atgaatactt gctagaaaat caccagcctt gtccatagct tcgatttcac
    20641 gagctgattt taatgttatc atcttttctc ctagtttcta attaatttta acagtcacat
    20701 ttgcttttga aacaatctgg tgaccatgat aaatatcgta atcaattata gctgaccgtc
    20761 tcgtatgatg aataatccgt gcctgaatgc gcaatatatc atctatctga acagcctgca
    20821 aaaagtagat tagcatctgc tcgataatga gattgcgacc actattaaca actaaatctt
    20881 gggtcatgtg ggtcagaatt tctgccaata caccattagc caaaactcca tttttttcta
    20941 gcataaaggg ttccactgta atgactactt catcatggtg ataagagagc ttttgtccaa
    21001 tctgctcaga aaaagttggt agagccgaaa cttgagaacg gctcatcttc tccatgacat
    21061 ctcgtcgcgt cacaacgcca agcaaagttt gattgcttcg aacaactggt accatttcaa
    21121 agtcttctgc gatcatccgt tgactcacat tggcaatatt tgtcgataat ccaaccaaaa
    21181 atagactacg agacataacc ttatcaattg tcgtgcttgg tgatttatca ccagcgtctc
    21241 tcatggttac aacgccaaca acgacctgat gttgattgat aacagggaaa cggctgctac
    21301 gattcttacg aaccaagtcc aaataatctt taactgtatc tgtctctctc agaaaaccat
    21361 actcatgact agggcgataa agtttctcaa ctgtcagaat atcagtcttg atttggacat
    21421 ttgacaaggc tttattgatc atggtcgcga cggtaaaggt atcatgctta cttcttagaa
    21481 caggaatccc tttttgattg gccagtttaa gcacatcatc atgaacctga aatccccctg
    21541 taaccagaac tgcattttca ttttccaagg ctagcaactg aatacgggtt cggtctccga
    21601 caatcaagag ccccccatca tgaaggtaag acaagatatt ttgttcagtc atggcaccaa
    21661 ttgaaaactt actaaattct ctctctaaac cttcttgccc agccagaacc tcagaagaag
    21721 tcacttctgc aatttcagca aatgttaatc tctctatagc aactttctgg gatttaacac
    21781 gaattgttcc acttctagga cgggtctcca caattccacg gttttcagct tctttaatag
    21841 cccgataggc tgttccatca ctaactccta gatgattcga aatgctacga acactgaccc
    21901 ttttacctac tggtaattcc tccaaatagc ttagaatttc ctgatgctta ctcattgaac
    21961 tctcctttta cataccgaaa ttcaagataa tcccgcattt ttcttgtgta acgatcactt
    22021 cccttaaact gacggaacaa actaaatcca gacttaagag caactctttg gctagcttca
    22081 ttttcaaggt gggtaatgat agataattgt tttaagccaa attcctcaaa agaaagctga
    22141 caaatttttc taacaacctc tgtcataaat ccttgcgacc aagcatcttt tctcaaaaaa
    22201 tagccaagct cagcttcttt tttgatttca tctaacttct caaatttaat agaaccaatc
    22261 atttgttgat ttttctggtc acaaattgcc cacactccca aaggggactt cataaagtaa
    22321 ttggccagtg catattgact ttcttccaga cttgcctgcg ttgggaaaat aaattgaaga
    22381 ttttctggat ttgaagctat ctcgcggaag tcctgactat cactaaaaaa gaaaggacgc
    22441 aaatacaagc gatccgtttc aaaaaaagaa aacattgcta atttggtcca aatattcata
    22501 aacacctcta cggtttaatc ctcaacaagt ctaatatccg ctcctaaatt acgtaatttt
    22561 tcgataatat cagaataacc acgtaagata aactcgatat tggtaatttc agttttacct
    22621 tcagccataa gcccagcaat gactagtgca gccccagctc ttaagtcggt cgctttaaca
    22681 ctggccccac gtaaatcacg tccacccgtg tacaaaatat gaccatttgt tgtcgaaata
    22741 tccgcatcca tctttgctag ttcaaaaaca tgatttacac gtttttcgta aatcgtatcg
    22801 acaattgtac cacgaccatt cgctcttagt aaaagagggg taagcggttg ttgcaaatca
    22861 gttgcaaagc ctgggtaagg agctgtctta atattgattg ctttcaaatt agactgttcc
    22921 tcgacaaaaa tgctgtcttc agatacagtc attctcactc ccatttcttc caacttagca
    22981 ataaaccctt ccaggtgttc gtaaagaaca ttatttatac gaattccttt accaactgca
    23041 gcagctaaag atatatatgt tccagcttca atgcggtctg gaatcacctg atgacgtgtc
    23101 ccatgtaatc tttcaacacc atcaataatg atgatattag ttcctgcccc acggatatgg
    23161 gcacccatat tattcaagag agtagctaca tcaataatct caggttcacg ggctgcattt
    23221 tcaataatag tacgaccatt tgctttaacc gcagcaatca tcgtattaat cgttgctccc
    23281 acactaaccg tatccatgta aatacttgca ccatgaagtc ctgtatcttt agcagataac
    23341 ttcatgttat ctccctcgta gctagcagtg gcacccatag cttcaaacgc cttaaggtgt
    23401 aagtcaatcg gacgaggacc aagatcacat cctcccggta gaccaactgt cgcttcacca
    23461 aaacggccta agaggctccc ataaaaatag taagatgcac gaagactgtt aattttacca
    23521 taaggcattg gaatattttg aacacctctt gggtcaatct ccaatacatc gtcataacgc
    23581 ttaacagtag ctcccatcaa ttccatgatt tcgacaagac tggctacatc cgaaatatct
    23641 ggaacgcaat ccaaagtcac cacatcatca gccaagataa tagctggaat taaggcaacg
    23701 acactatttt tagcaccact aatagtgatt tcaccttgca gtggtaatcc accattgata
    23761 acaatttttc tcattctaag ttttcaatac tctttcaaga tttctaataa ggtcttcaaa
    23821 ataaagtata tcataaattt atcctttttt ccatcctttt caattttatt ggataaatca
    23881 gagttgacga gttagtaact gaattactaa tactcaatga aaatcaaaga tcaaactagg
    23941 aaactaaccg caggttgctc aaaacactgt tttgaggttg tagatggaac tgacgtagtc
    24001 agtatcctac acatacggca aggcgatatt gacgtgattt gaagagattt tcgaagagta
    24061 taatctttct cgaatcgcta ttgccccttt tttatcccct aaaactgagt aggggctaag
    24121 actagatctc ttatctaagt atcggaatac ggctgttcaa ctaaatttta gcaagaactt
    24181 ctccccttct ctcaattcac agaagcgttt tatacatacc gtcctatcag acaatctatt
    24241 ttaaagataa ccgtgactca ggatcacttc tatctgtcgt tttctcttta ttaggttacg
    24301 actacctttt tggactttag agtttgaggc cctcttatcc gctatatacg ccttattatc
    24361 acgttcctgt tcgtagagcc acgatttctc tatcccttct tctgacaatt cttatttcca
    24421 gcgtcagact taaaacggtc tatccccaga ccattttaat ccgctacctc acgatagtca
    24481 ggcttgggaa tcgctatttg actcgccgag aactttgaca tcagatatac tataacaaat
    24541 tgaaataaga atcaaacaat ttaattttga aattcaaatc aatttataac aatatagt
//
LOCUS       DAVLDI010000035        24075 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLDI010000035 DAVLDI010000000
VERSION     DAVLDI010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24075
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.035"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(120..434)
                     /gene="trxA"
                     /locus_tag="VXD01_001398"
     CDS             complement(120..434)
                     /gene="trxA"
                     /locus_tag="VXD01_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV0601784.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(451..672)
                     /locus_tag="VXD01_001399"
     CDS             complement(451..672)
                     /locus_tag="VXD01_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV0601785.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(771..1151)
                     /locus_tag="VXD01_001400"
     CDS             complement(771..1151)
                     /locus_tag="VXD01_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV0601786.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(1294..2247)
                     /locus_tag="VXD01_001401"
     CDS             complement(1294..2247)
                     /locus_tag="VXD01_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0601787.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(2315..3523)
                     /gene="sstT"
                     /locus_tag="VXD01_001402"
                     /pseudo
     CDS             complement(2315..3523)
                     /gene="sstT"
                     /locus_tag="VXD01_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            3662..4222
                     /locus_tag="VXD01_001403"
     CDS             3662..4222
                     /locus_tag="VXD01_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV0601788.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            4279..5187
                     /locus_tag="VXD01_001404"
     CDS             4279..5187
                     /locus_tag="VXD01_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV0601789.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            5139..5729
                     /locus_tag="VXD01_001405"
     CDS             5139..5729
                     /locus_tag="VXD01_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV0601790.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYALTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            5732..6838
                     /gene="yqeH"
                     /locus_tag="VXD01_001406"
     CDS             5732..6838
                     /gene="yqeH"
                     /locus_tag="VXD01_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV0601791.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKNKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            7052..7363
                     /gene="yhbY"
                     /locus_tag="VXD01_001407"
     CDS             7052..7363
                     /gene="yhbY"
                     /locus_tag="VXD01_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV0601792.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            7415..8044
                     /locus_tag="VXD01_001408"
     CDS             7415..8044
                     /locus_tag="VXD01_001408"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV0601793.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            8044..8637
                     /gene="yqeK"
                     /locus_tag="VXD01_001409"
     CDS             8044..8637
                     /gene="yqeK"
                     /locus_tag="VXD01_001409"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV0601794.1"
                     /translation="MSYQDYINCSREALLERMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            8638..9138
                     /locus_tag="VXD01_001410"
     CDS             8638..9138
                     /locus_tag="VXD01_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0601795.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            9151..9504
                     /gene="rsfS"
                     /locus_tag="VXD01_001411"
     CDS             9151..9504
                     /gene="rsfS"
                     /locus_tag="VXD01_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV0601796.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            9607..10353
                     /locus_tag="VXD01_001412"
     CDS             9607..10353
                     /locus_tag="VXD01_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV0601797.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFSMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            10363..11460
                     /locus_tag="VXD01_001413"
     CDS             10363..11460
                     /locus_tag="VXD01_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV0601798.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            11698..11928
                     /locus_tag="VXD01_001414"
     CDS             11698..11928
                     /locus_tag="VXD01_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV0601799.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            12197..13810
                     /locus_tag="VXD01_001415"
     CDS             12197..13810
                     /locus_tag="VXD01_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV0601800.1"
                     /translation="MEFMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            13940..14566
                     /gene="gmk"
                     /locus_tag="VXD01_001416"
     CDS             13940..14566
                     /gene="gmk"
                     /locus_tag="VXD01_001416"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV0601801.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            14591..14905
                     /locus_tag="VXD01_001417"
     CDS             14591..14905
                     /locus_tag="VXD01_001417"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV0601802.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            14971..17367
                     /locus_tag="VXD01_001418"
     CDS             14971..17367
                     /locus_tag="VXD01_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV0601803.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGKADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            17380..18315
                     /locus_tag="VXD01_001419"
     CDS             17380..18315
                     /locus_tag="VXD01_001419"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV0601804.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            18308..19621
                     /gene="rsmB"
                     /locus_tag="VXD01_001420"
     CDS             18308..19621
                     /gene="rsmB"
                     /locus_tag="VXD01_001420"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV0601805.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDISSIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            19636..20376
                     /locus_tag="VXD01_001421"
     CDS             19636..20376
                     /locus_tag="VXD01_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV0601806.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIITSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            20373..22352
                     /gene="pknB"
                     /locus_tag="VXD01_001422"
     CDS             20373..22352
                     /gene="pknB"
                     /locus_tag="VXD01_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV0601807.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            22467..23225
                     /locus_tag="VXD01_001423"
     CDS             22467..23225
                     /locus_tag="VXD01_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0601808.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            23227..23676
                     /locus_tag="VXD01_001424"
     CDS             23227..23676
                     /locus_tag="VXD01_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV0601809.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            23738..24075
                     /locus_tag="VXD01_001425"
                     /pseudo
     CDS             23738..24075
                     /locus_tag="VXD01_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT         7162 a         4741 c         5620 g         6552 t
ORIGIN      
        1 gttttagaag tagaggtgta ctattctagt ttcaatctgc tatagtctag catatttttt
       61 gaaaaatggc aaagggcaag aaaaaagaga ccaaagaaag tacttggtct ctcgtttgat
      121 tagctcaatt cagcaatgat ggccttgatt tgttctgctg tgtgaacacc tgcaacttgt
      181 ttgacaactt ggccgtcttt tttgaagaga agagttggaa tagacatgat tccaaaagca
      241 cgagctgtgt ttggattttc atcaacgtcc attttaacga ttttcaagac atcttctgaa
      301 agttcttcag acaatttgtc caagattgga ccttgcatac gacatggacc acaccaagtt
      361 gcccagaagt ctactaagac caaaccgtct tttgtttctt gttcgaatgt tgcatctgta
      421 attgcttttg ccattgtatt tctccttttt ttagttatat tggcttaaat cttgtttcat
      481 gagatagaag aagatatctc cataagtccc atggtagtcc aaattatgac ccttgtaagt
      541 taatttttgg acagggtagt agtctgcgac gccgataagg caagcttgtt gcgaacgttc
      601 aaagtcttca taagactcga aagtcacagt tctttcgttc ttgctggcat ctatataggt
      661 aatttcaatc atgtttaaaa ctcctttgtt taatgctaac tttattttac tccttataaa
      721 agagaatgtc aagaaaaatg attgcgcacg caactttttt taaaatcatc ttaaatcaag
      781 aaatccaaac ctgcttccaa gctttcttcg acagtctttt gtagcgaggc cagtgtcttt
      841 tgcccatcat ttgtcaggca gataaaacta gagcgtctat cttgatggca acacatgcga
      901 ctgagtagac cgcaattttt agcttccaag cgagccacca tcctagaaac tgcgctcggg
      961 ctcagatgaa gcttatctgg caggtcaatc tggcgtagag atttttcttc agccaagtcc
     1021 agatagtaga gcaggtagaa ctctttcaag gtcagacttt gctcgctctg ttgggcaatg
     1081 gtctcttcca agagactttc aatttctttc tgacgccgat tgaagtcaaa ccatttttcc
     1141 aaataggtca tagtgtctcc tttcttttta gagtcataaa tagaagaaag tccattaacg
     1201 ggcagtctct gcgtcacaag atgattgcgc atgcaataat tatactactt ttcaagaatg
     1261 ctggcaagct ctgtttttta gtggttttat tttttactgt ctatattttt ggtaaaaatc
     1321 aacttttact tggatgaagg ttttggcttc acgtaggagt tgaagaaggg tggcgcgggt
     1381 ttcaaactct tctcttgtct tgggcagact gcggttccgg aagacttcca gataacgttc
     1441 aatttcatct agcaaatcag aagcaggatt ggtctggctc agttgacctg caatttttga
     1501 aaagagttgc gctaagatca ggctttcact ggcggcaagg tgacaagtgt taatctgttg
     1561 ggccatgttt ctcaggatac gactttgtcg ttgtctcatc tcaaagtagt ggatatggta
     1621 gtcggtctgg tgaaagaggt ggtcagagtg atccaaatag accagtctga gggcttcttt
     1681 caaaagcgtg tctaattctg ctaccagctg tgctcggttg cgtccgtctc ctctggataa
     1741 atagtatttg aagcgctgga ggatatcttt taacttttct tccaccagcg tgtggtagtg
     1801 ctggatttcc tcttctcgtg aaggcatata gagattaaca agcaaggcaa atcctgtacc
     1861 aatagcaaag agaaggaatt cgttgactag gaggtctgga gaggttgact cttgaaccaa
     1921 gagatggcta accaaaaccg tgcttggtgt gatgccaatt tcccagccca tcttgtaggc
     1981 taaaggaacg tagaaggcca gatagaggcc gagactccag atatgaaatc cgctcaagtg
     2041 aaaagctaga acaccgatag ccagagctag aagcatagaa aaaagacgat tgcgagccag
     2101 ttttaaagta cttctacgcg tatcagatag gctcaagaga gcgataattc cagccgaaac
     2161 tgctgacgaa agattgagaa aataagcaag caggcaggca agacaggtag ctaagatgag
     2221 cttggtcgta cgttggctaa tagacataag aatttcctaa taagttagaa taaaagcgta
     2281 aaagacaaga catgagcagg cttgccttga tgagttattt tttacgggtt gctgcgtatt
     2341 cggcaacggc ggtaaagagg acatctgtag aagagttaag ggctgtttca catgagtctt
     2401 ggatgacacc aatcacaaaa ccaaccccaa caacttgtat ggcaatatcg ttagaaatac
     2461 cgaaaaggct acaagcaact gggataagaa ggagggaacc tccggcaata cctgaagcac
     2521 cacaggctga gatagctgct accacactga ggacaaaggc tgtggcaaag tcaacaggaa
     2581 ttccaagagt gttaactgca gcaagggtca aaaggttaat ggtaatcgct actccagcca
     2641 tattgatagt agaaccgagt gggatagaaa cagaataggt atctgggttg agtccaaggt
     2701 catggcagag tttcatgttg acaggaatgt tagtcgcaga actacgagtg aaaaaggctg
     2761 tcacaccgct gacacggagg cagttccaaa ctagagggta aggattgcgt ctcataaaga
     2821 agaaggcaat caaagggttg accacagggg caacaaaaag catagtcgtt actaatagaa
     2881 ccaataaaat accgtagttg gcaaggcttc cgactccctt gtcagaaatg gttttaaaaa
     2941 caagaccaag gattccaaat ggagccagat tgatgatcca ttcgacaatt ttagaagtca
     3001 cgtcagcgat agtttttagc aattctttac tatttttact ggcttctctc atagcgattc
     3061 caaaaatgac tgcccaagat aagattctaa tatagttagc agtaagcagg gcgttgactg
     3121 ggttgtcaac cagtttgagc aagaggttgc tgaggacctg cccaatccca tctggtggtg
     3181 caatttcagt attggcacta tttagggtaa tttcaatagg gacgatgaaa cttgctagta
     3241 cagctacaag agcagcggcg aaagtcccta tcataggata tacaagaaaa caacagtttt
     3301 catattgcta tcttgtccct tttgatgttg gaaagggcat tggcaacgag ggcaaagact
     3361 aggataggag caacagcttt tagacctcca acgaataaat ccccgagtag cccaatccct
     3421 gagagattag gaagggtcag tcctaggatt ccccacaaag cataccaatc aagatacgct
     3481 tgacaaggct tgccttattc caagcatgaa tgattctttt cataataatc tcctttttgt
     3541 gtagtgatta tgattatagt ataaatgata gacaaaatca agaattttct gtctgttttt
     3601 tgaatattta tggagaatga gactgatgaa aatatggtat aatgaaataa aggagtttta
     3661 tatgcaaaaa tttattcagg cttatattga aaagctagat gtgacaacca ttatcgagaa
     3721 tattctaacc aaggtcattt ctcttttact gcttttgatt gtattttata ttgctaaaaa
     3781 aatgcttcat accatggtgc agagaattgt caaaccttct ctaaaaatgt ctcgtcatga
     3841 tgtcggacgc caaaaaacca tctcacgttt actagaaaat gtgtttaatt atacgctata
     3901 tttcttttta ctctactgca ttttgtcgat tttaggtttg ccagtttcta gtttgctggc
     3961 tggagctggt attgctgggg tagcgattgg tatgggagcc caaggctttc tgtctgatgt
     4021 catcaatggc tttttcatcc tctttgaacg tcaactggat gtgggagatg aggtcgttct
     4081 gacaaatgga ccgattactg tatcgggtaa ggttgtcagt gtgggaattc gtacgacaca
     4141 gcttcgtagc gaggagcaag cccttcactt tgtccctaac cgaaatatca cagttgttag
     4201 caatttctca cgcacagact agacctgtta ttttaagtaa tttgtggtac aatagaggga
     4261 gtttaataag gagaaaagat ggttttagaa aagcagttgg gcaatggttg tacctggata
     4321 gacctagacc taggaaagtt gaataaacta gaagaccttt ctgaaattta cggtttggac
     4381 aaggaaacca ttgaatacgc actggataga aacgagcgcg cccacatgga ttaccaccgt
     4441 gaaagtggga cggttacctt tatctataat gtcctagacg taaaaaagga caaggcctac
     4501 tatgagactt ttcccatgac ctttattgtc gagcatcgtc gcctgattac cattagtaat
     4561 accaagaacg cctatgtcat tgaacagatg actcgttatc tggagagcca tgacacgctt
     4621 tcgatttata agtttctctt tgccagtctg gaaattatca gcaatgccta ctatcctgtc
     4681 attgagcaga tggacaagag tagggatgag gtcaatgacc tcttgcgcca gcgaactacc
     4741 aagaaaaacc tctttgccct gtctgatttg gagactggta tggtttatct gacggcagct
     4801 gccaaacaaa atcggatttt gttagagcat attcaaggtc atgccttgta tcgtagtttt
     4861 gatgagattg agagagaaca gtttgatgat gccatgattg aggctcatca gctggtatcc
     4921 atgacagacc taatctctca gattttacag cagctttcag cctcttacaa caatattcta
     4981 aacaataatc tgaatgacaa tttgacaacc ttgactatca tttcagtctt gctagctgtt
     5041 ttggcagtcg tgacaggctt tttcggaatg aatgttccct tacctttaac agatgagccc
     5101 catgcttggc tctatatcag tttggctagt gcaggtttgt ggattgtttt atccttgtta
     5161 ctaaggaaaa ttgcgaaaaa aagttaagaa aaggagccag aatggcgatt gaaaattata
     5221 taccagattt tgctgtggaa gcagtctatg ctctgacagt cccaagcctg caggcgcagg
     5281 gaatcaaggc tgttttggtc gatttggata ataccctcat tgcttggaac aaccctgatg
     5341 gaacgccaga gatgaagcaa tggctacatg accttcggga cgcgggtatt ggcattatcg
     5401 tagtgtcaaa taacaccaaa aaacgcgttc aacgagcagt tgagaaattt gggattgatt
     5461 acgtttactg ggccttgaag cccttcacat ttggtattga ccgtgctatg aaggaattcc
     5521 actatgacaa aaaggaagtg gtcatggttg gcgaccagct catgacagat atacgagcag
     5581 cccaccgtgc agggattcgg tcaattttag tcaaaccctt ggtccaacat gactcaatca
     5641 aaacgcagat taaccgaact cgtgagcgtc gtgttatgag aaaaatcact gaaaagtacg
     5701 gaccgattac atataaaaaa ggaatttaac tatggaagaa attctctgta ttggttgtgg
     5761 agcaaccatt cagacgacag ataaagctgg tcttggtttt accccccagt cggcacttga
     5821 aaaaggtttg gagactggcg aagtctattg ccaacgctgt ttccgtctcc gccactacaa
     5881 tgaaatcaca gatgtccagt tgacgaacga tgatttcctc aagctcttgc acgaggtggg
     5941 agacagtgat gccttagtgg tcaatgtcat tgatatcttt gattttaatg gatctgtcat
     6001 cccaggttta ccacgtttcg tctcgggcaa tgatgtcctc ttggtaggaa ataaaaaaga
     6061 tatccttcct aagtcagtta agtctggtaa gattagccag tggctcatga aacgtgccca
     6121 tgaagaaggt cttcgtccag tcgatgtggt cctaacttca gcacaaaata aacatgccat
     6181 taaggaagtc attgacaaga ttgaacacta ccgtaagggc cgcgatgtct atgtggtcgg
     6241 tgtgaccaac gttggaaaat caactctaat caatgctatt atccaagaaa tcacgggtga
     6301 tcagaatgtc atcactactt cacgcttccc aggtacaacc ttggacaaaa tagagattcc
     6361 gcttgacgac ggatcttata tttacgatac gccgggaatt atccaccgcc accagatggc
     6421 tcactacttg acggccaaaa acctcaagta tgtcagtcct aaaaaggaaa tcaagcctaa
     6481 gacctatcag cttaatcctg agcaaaccct atttttaggt ggtttgggac gctttgactt
     6541 tatagcagga gaaaagcaag gatttactgc tttctttgat aatgaactca aacttcatcg
     6601 tagcaagctt gaaggagcta gtgctttcta cgataagcac ctgggaactc ttctgacacc
     6661 accaaatagc aaggaaaaag aagatttccc aaggctagtc cagcatgtct ttaccattaa
     6721 aaataagaca gacctagtca tctcaggcct aggttggatt cgtgtaacag gcatagcaaa
     6781 agtcgccgtc tgggcaccag aaggcgtcgc cgtcgtcaca cgaaaagcaa ttatttaaaa
     6841 caaaatcgct gagcgaacaa agtgagctca tatagcgata gttattgccg tggtgtgatt
     6901 gccaatctgt agattggcaa ggggcacaat tgagaccaag gctcaattgt gaggtcagga
     6961 aatccatttt tcaaagatga aatctttgga aaattagttc cgaccgtccc tcaccaccta
     7021 aaataactat ccaaaaacaa ggaagaaaat tatgtcatta acatcaaaac aacgtgcctt
     7081 cctcaacagc caggcacaca ccctcaaacc tatcatccaa atcgggaaaa atggactcaa
     7141 cgaccaaatc aaaaccagcg tccgtcaagc tcttgatgcg cgtgaattaa tcaaggttac
     7201 tctcttacaa aacacagatg aaaacatcca cgaagtagct gaaattttgg aagaagaaat
     7261 cggtgtggat acagtccaaa aaataggacg catcttgatt ttgtttaaac aatctagcaa
     7321 gaaagaaaat cgcaagattt ctaagaaagt caaagaaatc taagaccgaa actccaaata
     7381 actgttttta tagagaaata aaggggacta gcctatgaca atcgaactat tgactccctt
     7441 taccaaggta gagttggagc cagaaatcaa ggagaaaaaa cgcaaacaag ttgggatttt
     7501 aggggggaat tttaaccctg ttcacaatgc ccatctcatt gttgcggatc aagtacggca
     7561 acagttggga ctggatcaag ttctgctcat gcctgaatac caacctcctc acgttgataa
     7621 aaaggaaacc atccctgaac accatcgtct caagatgctt gagttggcaa ttgagggaat
     7681 tgacggccta gtcattgaaa ccattgagtt ggagcgcaag ggtatttcct acacctacga
     7741 caccatgaag attttgacag agaagaatcc agatacggat tattacttta tcatcggcgc
     7801 cgacatggtt gactatctgc ctaagtggta ccgaattgat gaactggttg acatggttca
     7861 gtttgtgggg gttcagcgtc cacgctacaa ggtagggact tcctatccag ttatctgggt
     7921 ggacgtaccg ctcatggata tctcgtccag catggtgcgg gacttcattg cccaaggtcg
     7981 gaaacccaac tttctcctac ctcagccagt gctagactac atcgagaagg aggggctcta
     8041 ctgatgtcct atcaagacta tatcaactgc tcccgtgagg ccttgttgga aagaatggca
     8101 gagcttctac ctgagaaacg tctaacccat tgtctaggtg tggagcgtgc cgctatggaa
     8161 ttagctcagc gctttggtgt agatgttgag aaagcaagtc tagcaggtct tcttcatgac
     8221 tatgctaaaa agttgtcaga tcaggaattt ctagacttga ttgaccgtta ccagctagat
     8281 ttcgacctca aaaactgggg taataatgtc tggcatggta tggtcggaat ttacaaaatt
     8341 caggaagatt tggatttgca tgattcagaa atcctgcgag ccattgaagt ccatacagtc
     8401 ggtgctggtc aaatgacaga cctagataag gtcatctacg tcgcagacta tatcgagcac
     8461 aatcgagcct ttcctggagt agatgtggcg cgtgagattg caagtctatc gctcaataag
     8521 gcggtggcct acgaaacagc tcgtaccgtg gagtatctag ctcatcaggg attccccatc
     8581 tatccccaaa cccttgaaac ctataacgcc tttgtgcact atttgaaaga gaactaaatg
     8641 aagacggctt ttataatcat tgatgttcag aatgttttag tagaaactgg gttccagaca
     8701 aaaagtctat tgggaaaaat ttcttattta caaaaccagg ctagaagcaa gaatattgaa
     8761 attatctatg ttcaacatat tgagaactct gaagctcaaa catcagaaga ttggcagtta
     8821 tctgcgcttt taaatcgaaa acctgctgaa aaggtctttc agaagaagta taacagtatt
     8881 ttcaaagaaa ctggcttaaa agaatacttg gataagcagg ggattgaaaa attagtttta
     8941 tgtggtatgc agacagaata ttgtgtggat acctctgtca aggttgcctt tgaatatggc
     9001 tatcagctta ttgttccaga aggtgctgtc acaacctttg atggggatga cattccagca
     9061 gaaacgatta atgaatttta tgaggacatt tgggaggagc gctttgcaga tgtcctagat
     9121 tacaaacata ttttctaaaa agaggattaa atgaacgaaa aagaattact agaactagtc
     9181 gtgaaagcgg ctgatgagaa acgtgcggag gatatcctcg cacttgatgt acaagatttg
     9241 actagtgtga cggactactt tgtcatcact agctcaatga atagccgtca gttggacgct
     9301 atcgcagcta atatccgtga aaaagtagct caagcgggct ttaaaggtag ccatgtcgaa
     9361 ggcgatgcag ctggaggctg ggtcttactg gacctcggtg ctgttgtcgt gcatatcttt
     9421 tcagaagaaa tgcgtgccca ttataatcta gagaagctat ggcatgaggc gaattcagta
     9481 gatatttcag aagctcttgc ttagaagatg aactcagttg tagtcaactg ggtttctttg
     9541 cttattttag aaaaattgat agaaaggtaa agggctagtg gtgtttacca tggagctctt
     9601 agtatcatga ttatggcgac ttatgaaacc tttgcggcgg tctatgatgc ggtcatggac
     9661 gatagtttat acgacaaatg gacaaatttt tctctgcgtc atttgcctaa gaccaaggag
     9721 aaaaagaaac tcttggaact ggcttgtggg acaggaattc aatcagtgcg cttctctcag
     9781 gctggttttg atgtgactgg acttgacttg agtgcggata tgttgaagat tgcggagaag
     9841 agagcaactt cagccaagca aaagattgct tttatagaag gtaatatgct aaatttgtcc
     9901 aaggcaggga aatacgattt tgtcacgtgt tattcggact ctatctgcta tatgcaggat
     9961 gaggtggaag taggggacgt ctttaaggac gtgtacaatg cgctgaatga agagggagtt
    10021 ttcatctttg acgtgcactc gacctaccag acagatgaag tattccctgg ctattcctac
    10081 catgaaaatg cggaagattt ttccatgctt tgggatacat atgaggacga agttcctcac
    10141 tccatcgtgc atgagctgac tttctttatc aaggaggctg acggttcctt tagtcgccac
    10201 gatgaagtac atgaggagag gacctatgag atcttgacct atgatatctt gctggaacag
    10261 gctggattca agtccttcaa actctatgca gactttgagg ataaggagcc aacagaaact
    10321 agcacccgtt ggttttttgt ggcgcagaag taggagatta gcatgaccat cacaggtatt
    10381 atcgcggagt tcaatccttt tcataatggc cataaatacc tgctggatca ggcagaggga
    10441 ctgaaaattg ttgccatgtc agggaatttc atgcagcgtg gagagcctgc tattgtggat
    10501 aagtggacaa gggcccagat ggcgctggaa aatggcgcag acttggtagt ggaattgcct
    10561 tttttagtca gtgttcaggc agctgatttc tttggtcaag gagctgtgga tatcttggat
    10621 cgcttgggca ttgatagtct agtttttggg acagaggaag ttcgagatta tcagaaaatc
    10681 gctgacttat acacagagaa aggtgctgag atggagaaat ttgtggaaaa tctgcctgat
    10741 tccctttcct atccccagaa aacccaagct atgtggaagg aatttgctgg tcttgatttt
    10801 tcaggtaata cccccaatca tgttcttgct ctggcctatg caaaggcggt tgcaggacga
    10861 aatatcaagc tgcatccgat tcagcgtcag ggggcaggtt accattctgt gaataaagat
    10921 gtggactttg cctcggcgac agccctccgt caacatcaga aggaccaaga tttcttagaa
    10981 cgttttatgc cttctgttgc cctatttgag caggccagta aggtgatctg ggaagactat
    11041 tttcccttgc tccgctatca aatcttgtca aatcctgacc taaccaccat ctatcaggtc
    11101 aatcaagaaa tggctgtgcg cattaaagaa gctattaaaa cagcccagtc tgtggaagaa
    11161 ttggtcgagt tagtgactac caaacgttac accaaggcgc gtgtcagacg cctattgacc
    11221 tatattttga tgcaggctag agaaagtgac ttgccagaag ccattcatgt ccttggattt
    11281 actgaaaaag gtaggcaaca tctcaagtct ttgaaaggtc aggtcagtct agtcagccga
    11341 attggcaaag aaccttggga tgctatgact caaaaggttg accagattta ccaactagga
    11401 aagccaagta tagcagagca aaattttggc agagtgccga ttagaataga aacaaactaa
    11461 gtctaccgaa aggtggactt tttgagattt tttacgaata atactcttcg aaaatcaaat
    11521 tcaaatcgcg tcaacgtcgc cttgccgtac tcaagtacag cctgcggcta gtttcctagt
    11581 ttgctctttg attttcattg agtataaata gatagaaaag aaaatcttgt acaagttcct
    11641 gacaatttct ttcttttcgt gtataatagt ggaaaagagc taaaacgagg tatggttatg
    11701 gaagcagtcc tttactcaac attccgaaat catttaaagg actacatgaa gaaggtaaat
    11761 gatgaatttg agcctttgac ggtggtcaat aaaaatccag atgaggacat tgtagttctt
    11821 tcaaagagcg aatgggacag tattcaggaa accctgagaa tcgcccaaaa taaggagtta
    11881 tcagacaagg ttttacgagg aatggataaa attcgcgcag gacactagtc taatttacag
    11941 agaatacctg agtgaaatct tgctgttgtt agaaacaaac ttcttgtatt tcataatcat
    12001 taggaagtct actgcaaagt aggctttttc tcaagtctct actaaactac tatttctaaa
    12061 aaacaagttt attttggtaa atgtgttcca aattccccaa aacatattct attttaggtt
    12121 tgtgaaaatc acttttttat ggtagaatgt aaaagaatgt atgtcattcg gaataacaat
    12181 aaaatgaggt aaaaacatgg agttcatgtc gcttgcgatt gctgtttttg ccgtcatcat
    12241 tggtttagtc attggatatg tcagcatctc agctaagatg aaatcatctc aggaagctgc
    12301 agagttgatg cttttaaatg ctgaacaaga agcaactaat ttacgtggac aagctgagcg
    12361 tgaagcggat ttacttgtta atgaagccaa acgtgaaagc aagtctctta aaaaagaagc
    12421 actattggag gccaaagaag aagccagaaa ataccgtgaa gaagtggacg ctgaattcaa
    12481 atcagaacgt caagaactca aacaaatcga aagtcgtttg acagagagag ctactagcct
    12541 tgaccgtaag gacgacaatt tgacgagtaa agaacaaaca cttgaacaaa aagaacaaag
    12601 tatttctgat agagcgaaaa accttgatgc gcgtgaagag caattagagg aagtcgaaag
    12661 acaaaaagaa gcagaactag agcgtattgg tgctctgtct caggcagaag cacgagatat
    12721 tatcttggct cagacagagg aaaacttgac cagggagatt gccagtcgca ttcgcgaagc
    12781 tgagcaagag gtcaaggaac gttctgacaa aatggccaag gacatcttgg ttcaagctat
    12841 gcaacgtatc gctggtgaat atgtagcgga gtcaacaaac tcaacagttc atctgccaga
    12901 cgatactatg aagggacgca ttattggtcg tgaaggtcgt aacattcgta cctttgaaag
    12961 tttgacaggg gtcgatgtga ttatcgacga tacaccagaa gtggtgacct tgtcaggatt
    13021 tgatccgatt cgtcgtgaga ttgcccgtat gactatggaa atgttgctca aagatggtcg
    13081 tatacatcca gctcgtatcg aagagttggt tgagaaaaac cgtcaagaga ttgacaataa
    13141 gattcgtgaa tacggtgagg ctgctgccta tgaaattggt gcgccaaacc ttcatccaga
    13201 cttgatgaag attatgggac gtttgcagtt ccgtacttca tatggacaaa atgttttgcg
    13261 ccattcgatt gaggttgcta agttggctgg tatcatggcg agcgaacttg gtgaaaatgc
    13321 ggctcttgcc cgtcgtgctg gattccttca cgatatcggg aaagccattg accatgaggt
    13381 tgaaggtagc cacgttgaaa tcggtatgga attggcccgt aagtacaagg aacccccagt
    13441 tgtggtgaat acgattgcta gtcaccacgg agatgttgaa gctgagagcg tgatagcagt
    13501 tatcgtcgct gcagcagatg ccttgagcgc agcccgtcca ggtgctcgta gtgagtctct
    13561 tgaaagctac atcaagcgtc tccatgattt ggaagaaatt gctaacggct ttgaaggagt
    13621 gcaaactagc tttgcccttc aagcaggacg tgaaattcgt atcatggtca atccaggaaa
    13681 aatcaaggac gacaaagtca caatcttggc tcacaaagtt cgtaagaaaa ttgaaaacaa
    13741 tctcgattat ccaggaaata tcaaggtaac cgtgattcgc gagcttcgtg cagtagatta
    13801 tgctaaataa ataagaaaga gcagttgaaa aattactgct tttttgttac actagataga
    13861 aagactgtaa aggataatct ggctttttgc cattattcta gagaaatgtt atttcacaga
    13921 ttgactaaaa ggagacacaa tggcagaccg aggcttacta atcgtttttt ctggtccttc
    13981 aggggttgga aaaggaacgg ttagaagaga gatttttgag agttctgaaa accaatttca
    14041 atattctgta tcgatgacga cacgcgcaca acgtcctgga gaagtggacg gtgttgacta
    14101 tttcttccgt actcgtgaag aatttgaaga gctgattcgt caaggacaga tgttggaata
    14161 cgcagaatat gtcggtaact actatggaac tcctctgacc tatgtcaatg aaaccttgga
    14221 caagggaatc gatgttttcc ttgaaattga agttcagggt gctcttcagg tcaagaaaaa
    14281 ggttccagat gctgtcttta tcttcctgac accaccagat ttggatgaat tgcaagatcg
    14341 cttggtaggt cgtggaacag atagtgcaga agtgattgcc caacgaatcg aaaaggccaa
    14401 ggaagaaatt gccctcatgc gtgagtatga ttatgcgatt gtcaacgatc aggtgcccct
    14461 agctgctgaa cgtgtcaaat gtgtgattga agcagaacac ttctgtgtgg atcgtgtcat
    14521 tggtcactat caggagatgt taccaaaatc tccaactacc cgataaaatt tagaaaatag
    14581 gtacaagcaa atgatgttaa aaccctctat tgataccttg ctcgacaagg ttccttcaaa
    14641 atattcactc gtaatcttgg aagcaaaacg tgcccacgaa ttggaagcag gtgccccagc
    14701 aactcaaggt ttcaagtctg aaaaatcaac tcttcgcgct ttagaagaaa tcgaatcagg
    14761 aaacgttaca attcacccag atccagaagg aaaacgtgaa gcagtgcgtc gccgtatcga
    14821 agaagagaaa cgccgcaaag aagaagaaga aaagaaaatc aaagagcaaa ttgctaaaga
    14881 aaaagaagat ggtgaaaaaa tttaaggttg gggggactca atcttatttt ttctattgca
    14941 agaatgtact gacaaggagg aggtgagaag atggccctag ctaagattat cgtagatgtg
    15001 cccttgatgc agacggacca gccctatagt tacaggattc cggaggaatt tgagggaatg
    15061 ctggaagttg ggatgcgggt tcatgtacct tttggtaagg gtaatcgcct gattcaaggg
    15121 attgttcttg gtttggagtc ccaatcagat ggagaagaga tggagcaaga tttaaaagat
    15181 attgcagagg tgctggattt ttctcctgtt ctcacgccag aacaactctg gctggctgag
    15241 gagttacgca aatctgtctt ctcctacaaa atctctatcc tcaaggccat gcttccagga
    15301 tttctgaatt ctagctatga caagattctc tatcctctgg aaggcttgag tcaggaagaa
    15361 cgagtacgcc tgtttggttc agaagattcg ctagcctttt cttcactaga ccttgccaag
    15421 caagctgaaa tgatgcgttt gactagaaaa ggcctgcttg gtctggaata tcaggcagtc
    15481 gatcaaaaga aggtcaagac ccagtcttgg tatgaggttg accatgccca attagaaggt
    15541 gttgagattt ctacacgtgc caagaaaaag ttggaactga gagattatct gctgtctcat
    15601 ccagagagcg cttccttggc tagcttgtta gagtcctact cgcgagagca agtcaacttc
    15661 tttgtggatc aaggtgctgt taccatagtc caaaaggaag ttcaacgctc ggctgcttat
    15721 tttgaaggaa ttgaagcaag tagacctttg gagttaaatc cagaacaaag acaggcgcgt
    15781 gatgcggttg tgagttctat tggcagttct caacctccct ttctacttca agggattaca
    15841 ggaagtggga agaccgaggt ttacttgcag attatccaag gtgccctgga taagggcaag
    15901 acagctattt tgctggtacc tgagatttcc ttgactcctc agatgaccga gcgttttata
    15961 gcacgttttg gggacaaggt agccattctt cactcaggat tatccaatgg tgaaaagtat
    16021 gatgaatggc gcaaggtgga gcgtggcgat gcccaagttg ttgttggtgc cagatctgct
    16081 atctttgctc ctctgaaaaa tctgggtgtc atgattattg atgaagagca tgaagcggct
    16141 tataagcagg acagcaatcc ccgttaccat gccagagagg tagctatttt acgggctcag
    16201 tataatcaag caactctggt acttggatct gcaacgccga gcttagagag ccgggcgcgt
    16261 gctggcaaag gcgtctatca acacttacgt ctaacccaac gtgccaatcc tttggctaca
    16321 atccctgagg ttcaagtgat tgactttcga gactatatcg gacaaaatga gacgtcaaac
    16381 tttacgcctc ctttgctaga ggctatccaa gaccgtctgg ttaaaaaaga gcaggtggtt
    16441 ctcatgctca atcgccgtgg ttattctagc tttgtcatgt gtcgggagtg tgggacggtg
    16501 gatacttgtc ccaactgcga tatttctctg accttgcata tggataccaa gactatgaac
    16561 tgccattatt gtggtttctc gaaggatatt cctcaggtct gtcctaactg taagagccac
    16621 agtattcgtt actatgggac gggaactcag aaggcttatg atgagctagc agaactcttt
    16681 ccccaagctc gcattctgag gatggatgtg gatacgactc gaaaaaaagg cagtcaccaa
    16741 gccttgcttg atcagtttgg gcgagggaaa gcggatattt tacttggtac tcagatgatt
    16801 gcaaagggtt tggattttcc caatgttacc ctagtcggag ttctaaatgc ggatacggcc
    16861 ttgaatctgc ctgatttccg ttcttctgag agaaccttcc agctcttgac tcaggtggca
    16921 ggtcgagcag gtcgggctga aaaagcaggt caagtcttga tacagtccta caattcgcag
    16981 cactatgcta ttcgatttgc caaggatcaa gattacgaag gcttttatgc ctatgaaatg
    17041 ggaatcagac gacaactcgg ctatccacct tactatttca cgattggtat taccctttct
    17101 cacaagaaag aagaagaggt tttcaaacgt gcctatgaag tcatgaacat tttgcggtca
    17161 ggcttgtcag agaccagtcc cattctgggg ccaacgccaa aaccgattgc ccgtacccac
    17221 aacctctatc attaccagat tttaattaaa taccgtttag aagatgagct ggggccgacc
    17281 ctcaaccagg tcttggcctt gactcaagaa cgggaaaata gtgagctccg tctcagcatt
    17341 gaccatgagc cgcagcaatt tttataaaaa ggagaagata tgacaaaact aatctttatg
    17401 gggacccccg acttttcagc aacagtctta aaaggacttt tgacagatga ccgttacgaa
    17461 attctagccg ttgtgaccca gccagaccgt gctgttggtc gtaaaaaagt tatccaagaa
    17521 accccagtca agcaggctgc caaggaagca ggactatcta tctaccaacc tgaaaaatta
    17581 tctggaagtc cagagatgga agatcttatg aagctaggag cagatggaat tgtgactgct
    17641 gcttttgggc agtttctccc aagcaaactc cttgatagca tggactttgc tgtcaacgtt
    17701 catgcctccc tccttcctag acaccgtggt ggtgcgccta tccattatgc cttgattcaa
    17761 ggggatgagg aagctggtgt gaccatcatg gaaatggtta aggaaatgga tgcaggagat
    17821 atgatttctc gtcgcagcat tccgatcaca gatgaggaca atgttggcac cttgtttgaa
    17881 aaattggcgc tagttggtcg tgatttgctt ttggacactc tgcctgccta tattgctggt
    17941 gatatcaaac ctgaaccgca ggatacgagt caggttacct tctctccaaa tataaagcca
    18001 gaggaagaaa aactggactg gaacaaaacc aatcgtcaac tctttaacca aattcgtgga
    18061 atgaacccct ggcctgttgc ccatactttc cttaagggcg accgctttaa gatttatgaa
    18121 gccctaccag tagaaggtca gggaaatcca ggtgagattc tctctatcgg caagaaagaa
    18181 ttgattgtcg caacggctga aggggctcta tccctcaaac aagtgcagcc agctggtaag
    18241 cctaagatgg acattgcttc cttcctcaac ggagttggac gtacattgac tgtaggagaa
    18301 cgatttggtg actaaagtag aaacggctag aagtttagct ctagcagtgc tagaggatgt
    18361 ttttgtgaac caagcatact caaatatcgc cttaaataag catctaaagg gaagtcaact
    18421 tttggcagca gacaagggct tagtgaccga gctggtctat ggaacggtag cccgtaaact
    18481 gactctggaa tggtacctat cccactttat cgaagacaga gaccagttag acagctggct
    18541 ctatgtcctt cttctcatga gtgcctacca actccgctat ttggacaaga ttccagatca
    18601 tgctgtggtc aatgaagcag tggaattggc caaacttcgt aaaaaaggca gtgaaaaatt
    18661 ggtcaatgcc ctccttcgcc gtatcttgcg tgaaggctgg ccagatattt ctagcatcaa
    18721 gcgaaaaaac aagcgtgact ccattgccta ttctctccca gtttggctag ttgccaaact
    18781 caaggaagaa tacggagagg agagagcaaa agccatcttt gaaagcttgt tagtgcgaaa
    18841 caaagccagt attcgtgtaa cagacctaag tcgaaaagag gaaatccaag ccttgttgga
    18901 ggcgaataat tcccttttag caaccactgg tctggttaag gagcaggggc attttgcagg
    18961 gcataatttg tttgcggatg gagccattac catccaagac gagtccagtc agctggttgc
    19021 tccgacgctt gatttacaag gtgatgagcg agtgcttgat gcctgtgcgg ctccaggtgg
    19081 gaaaacagcc catatagcct cttatcttac gacaggtcag gttactgctc tggacttgta
    19141 cgaccacaag ttggatttaa ttcaagaaaa tgcccaacgt ctgggagttg cagatcgggt
    19201 tcaaactcaa aaattggatg ccagaaaggt gcatgagttt tttgaccagg attcctttga
    19261 taagattttg gtggatgctc cttgttcagg aatcggtctt ttgcgccgaa aaccagatat
    19321 caaatacaat aaagaaacgg cagatttcgc gtccttgcag gaaattcagt tagaaatatt
    19381 aggtagtgtt tgtcaaatac taggcaaagg tggtataata acttatagca cctgcactat
    19441 cgtctcagag gagaattttc aagtcgttaa ggccttttta gagagtcatc ccgagttcga
    19501 gcaggtaaaa ctagaacatg aatgtaagga tatcatgaaa gacggctgta tcctcattac
    19561 acctgaattg tatggaagtg atggattctt catcagtcaa tttcgcaaga tatcggatta
    19621 ggaaggaact gacacatgga aatttcatta ttaacagatg ttggtcagaa acgaacaaat
    19681 aaccaagact atgtcaacca ctatgtcaat agagctggac gtaccatgat tattttagct
    19741 gatgggatgg gaggtcatcg cgcagggaat atcgctagtg aaatggcggt cacagacctg
    19801 ggtgtagctt gggttgatac tcagatcgat acagtcaatg aagtgcgtga atggttcgcc
    19861 cattacctag aaattgaaaa tcaaaagatt caccagcttg gtcaggatga agcttacaga
    19921 ggcatgggaa ctactttgga agtccttgct attattgata atcaggctat ctatgctcat
    19981 attggtgatt cgcgtatcgg cttgattcgt ggagaagaat accatcagtt gacgagtgat
    20041 cattctttgg ttaatgaatt gctcaaggct ggtcaattga caccagaaga ggcagaagct
    20101 catccgcaaa aaaatattat cacccagtct attgggcaaa aagatgaaat tcagcctgat
    20161 tttgggacag ttatccttga gtcaggtgac tatctcttgc tcaatagtga cggcttgacc
    20221 aacatgattt caggcagtga gattcgtgat attataacca gtgatattcc tttagcagat
    20281 aaaacggaga cacttgttcg ttttgctaac aatgcaggag gtttagacaa cattacggtt
    20341 gcccttgttt ctatgaacga ggaggatgaa gaatgatcca aatcggcaag atttttgccg
    20401 gacgctatcg gattgtcaaa cagattggtc gaggaggcat ggcggatgtc tacctagcca
    20461 aagacttaat cttagatggg gaagaagtgg cagtgaaggt tctgaggacc aactaccaga
    20521 cggacccgat agctgtagct cgttttcagc gtgaagcgag agctatggca gatctagacc
    20581 atcctcatat cgttcggata acagatattg gtgaggaaga cggtcaacag tatcttgcaa
    20641 tggagtatgt tgctggacta gacctcaaac gctatatcaa ggaacattat cctctttcta
    20701 atgaagaagc agtccgtatc atgggacaaa ttctcttggc tatgcgcttg gcccatactc
    20761 gaggaattgt tcacagggac ttgaaacctc aaaatatcct tttgacacca gatgggacgg
    20821 ccaaggtcac agactttggg attgctgtag cctttgcaga gacaagtctg acccagacta
    20881 actcgatgtt gggctcagtt cattacttgt caccagagca ggcgcgtggt tcgaaggcga
    20941 ctgtgcagag tgatatctat gccatgggga ttattttcta tgagatgttg acaggccata
    21001 tcccttatga cggggatagc gcggtgacca ttgccctcca gcatttccag aaacccctgc
    21061 cgtccgttat tgcagaaaat ccatctgtac ctcaggcttt agaaaatgtt attatcaagg
    21121 caactgctaa aaagttgacc aatcgctacc gctcggtttc agagatgtat gtggacttgt
    21181 ctagtagctt gtcctacaat cgtagaaatg aaagtaagtt aatctttgat gaaacgagca
    21241 aggcagatac caagaccttg ccgaaggttt ctcagagtac cttgacatct attcctaagg
    21301 ttcaagcgca gacagaacac aaatcaatca aaaacccaag ccaggctgtg acagaggaaa
    21361 cttaccaacc acaagcaccg aaaaaacata gatttaagat gcgttacctg attttgttgg
    21421 ccagccttgt attggtggca gcttctctta tttggatact atccagaact cctgcaacca
    21481 ttgccattcc agatgtggca ggtcagacag ttgcagaggc caaggcaacg ctcaaaaaag
    21541 ccaattttga gattggtgag gagaagacag aggctagtga aaaggtggaa gaagggcgga
    21601 ttatccgtac agatcctggc gctggaactg gtcgaaaaga aggaacgaaa atcaatttgg
    21661 ttgtctcatc aggcaaacaa tccttccaaa ttagtaatta tgtcggccgg aaatcttctg
    21721 atgttatcgc ggaattaaaa gagaaaaaag ttccagataa tttgattaaa attgaggaag
    21781 aagagtcgaa tgagagtgag gctggaacgg tcctgaagca aagtctacca gaaggtacga
    21841 cctatgactt gagcaaggca actcaaattg ttttgacagt agctaaaaaa gctacgacga
    21901 ttcaattagg gaactatatt ggacggaact ctacagaagt aatctcagaa ctcaagcaga
    21961 agaaggttcc tgagaatttg attaagatag aggaagaaga gtccagcgaa agcgaaccag
    22021 gaacgattat gaaacaaagt ccaggtgccg gaacgactta tgatgtgagt aaacctactc
    22081 aaattgtctt gacagtagct aaaaaagtta caagtgttgc catgccgagt tacattggtt
    22141 ccagcttgga gtttactaag aacaatttga ttcaaattgt tgggattaag gaagctaata
    22201 tagaagttgt agaagtgacg acagcgcctg caggtagtgt agaaggcatg gttgttgaac
    22261 aaagtcctag agcaggtgaa aaggtagacc taaataagac tagagtcaag atttcaatct
    22321 acaaacctaa aacaacttca gctactcctt aaaagcagat ggataatcaa aatgagtaat
    22381 caatctttgt catgatttca tggcaaagat tttttttgag tccagatttg tgatagaata
    22441 gagggagttg ataaaaggag gaaagcatgg aagaatcaaa agaattaaat gccgtcattg
    22501 atgtgattat gctagcgggg actattctcc ttaaaagtgg ctcagaaatc catcgtgtag
    22561 aagataccat gattcgaatc gcgcattcgc aggggattgt ggattgcaat gtccttgcca
    22621 tgcctgccgc tatctttttc tctattgaaa ataccaatat ttcgcgcatg aagcgcgtga
    22681 cctcctcttc ttataacatc gaaaaagtct gcgatgtgaa ccagatttct cgtcagctag
    22741 ttggggggca gattgactta gaaacagcct ttaagcaatt gacggccttg caagctcaac
    22801 cccttcccta tactaagttg caggtaactc tggctgcgac ctttagtgct cctttctttt
    22861 cagttatgtt tagcggaaat atctacgacg cacttggggc aggagtggcg accttatttg
    22921 gttttgcctt ttccctctat gtggaaaaat ttatccgaat tccctttgtg acagcctttg
    22981 ctggagcctt tgtctttggg ataattgccc agttttgggc tcgctacaca ggttttcctt
    23041 caacggcaga tttgattata gctggtgcgg tcatgccgtt tgtaccaggt attgccttga
    23101 ccaatgcggt ccgtgatatt atgaccaacc acataaactc tggtatgagt aagatgtttg
    23161 aatccctgct cattaccctc gctttagggg caggaacttc tgtcgccttg gtattgatga
    23221 actaatatga cactaacaac ctttttatta caagcagtag caagttttct tgccattatc
    23281 acttttttaa tcgtactcaa tgtgcaacgg tctatgctct tacctggagg gattttgggc
    23341 atgactgtct ggctaatcta tctcttgctc aaggaaccga ccaatgtcat tgtagctacc
    23401 ttcattgcag ccattattgg ttcttgtgtc agccagattt taagtattct ttataagaca
    23461 cctgctgtgg tctttatctt ggccattttg gcaccgctgg ttccaggtta tctctcctac
    23521 cgaacaactg ccttttttgt gacaggggac tataataaag cactggcaag tgcgaccttg
    23581 gttgtcatgt tggctttggt aatctctatt ggaatggcta gcggaacagt gattctcaga
    23641 ctgtatcatt atataaaaac acatcgagta tcgtagactt tacagaaata aaagaatttt
    23701 ctgaaaaatg agataaataa attaacaacg ctttctatat gtgcgagaat accgcactta
    23761 tgaagaaatt gcggctgatt ttggtatcca cgaaagcaac ttactccgtc ggagccaatg
    23821 ggttgaagta actcttgttc aaaggtggtg ttacgatttc aagaactcct ctcagttctg
    23881 aagacacggt aatgattgat gcgacggaag taaaaatcaa tcgccctaaa aaaaacaatt
    23941 agcgaatgat tctggtaaaa agaaatttca cgctatgaag gctcaagcga ttgtcacaag
    24001 tcaagggaga attgtttctt tggatatcac tgtgaactat tgtcatgata tgaagttgtt
    24061 caaaatgagt cgcag
//
LOCUS       DAVLDI010000036        23254 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLDI010000036 DAVLDI010000000
VERSION     DAVLDI010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23254
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.036"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            527..901
                     /locus_tag="VXD01_001426"
     CDS             527..901
                     /locus_tag="VXD01_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV0601810.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLGRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            1109..2011
                     /locus_tag="VXD01_001427"
     CDS             1109..2011
                     /locus_tag="VXD01_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601811.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFVIIMLTTIFFWNIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIIINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            2067..2399
                     /locus_tag="VXD01_001428"
     CDS             2067..2399
                     /locus_tag="VXD01_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV0601812.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICAALAMSPGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            2396..3124
                     /locus_tag="VXD01_001429"
     CDS             2396..3124
                     /locus_tag="VXD01_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601813.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IRKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVANHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIVYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            4260..4499
                     /locus_tag="VXD01_001430"
     CDS             4260..4499
                     /locus_tag="VXD01_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601814.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            4484..4762
                     /locus_tag="VXD01_001431"
     CDS             4484..4762
                     /locus_tag="VXD01_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601815.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVASDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            5048..6937
                     /gene="pspA"
                     /locus_tag="VXD01_001432"
     CDS             5048..6937
                     /gene="pspA"
                     /locus_tag="VXD01_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEV0601816.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAMKNAEDAKKAVEDAQKALDDAKAAQKKYADDQKKTEEKAKKEKEASKAEQAAN
                     LKYQQELVKYIKYIRENNPKKTEAQKAMDEAEKEHKKKQAEFKKVRLEVIPSAKELEE
                     TRQKAKEAKEKEPELTKKVAEAKAKLEEAEKKVTEAKQKVDAEHAEEVAPQVKIAELE
                     NQVHKLEQKLKEIDESDSEDYVKEGLRAPLQSELDTKKAKLLKLEELSGKIEELDAEI
                     AELEVQLKDAEGNNNVEAYFKEGLEKTTAEKKAELEKAEADLKKAVDEPEKPAEESEN
                     PAPAPKPAPAPAPKPEQPAPAPAPKPEKSADQQAEEDYARRSEEEYNRLTQQQPPKAE
                     KPAPAPAPKPEQPAPAPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMA
                     TGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGA
                     MKASQWFKVSDKWYYVNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNA
                     NGSMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNA
                     NGEWV"
     gene            7338..8459
                     /gene="mnmA"
                     /locus_tag="VXD01_001433"
     CDS             7338..8459
                     /gene="mnmA"
                     /locus_tag="VXD01_001433"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV0601817.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKALSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTCDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            8600..9055
                     /locus_tag="VXD01_001434"
     CDS             8600..9055
                     /locus_tag="VXD01_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0601818.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVREELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            9065..10978
                     /gene="mnmG"
                     /locus_tag="VXD01_001435"
     CDS             9065..10978
                     /gene="mnmG"
                     /locus_tag="VXD01_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV0601819.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKIVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            11182..11259
                     /locus_tag="VXD01_001436"
                     /pseudo
     CDS             11182..11259
                     /locus_tag="VXD01_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(11357..13036)
                     /locus_tag="VXD01_001437"
     CDS             complement(11357..13036)
                     /locus_tag="VXD01_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV0601820.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(13038..13271)
                     /locus_tag="VXD01_001438"
     CDS             complement(13038..13271)
                     /locus_tag="VXD01_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV0601821.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDTSSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            13551..13766
                     /locus_tag="VXD01_001439"
     CDS             13551..13766
                     /locus_tag="VXD01_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601822.1"
                     /translation="MYNLFAFAIGARLVAFIVFVACVYAGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            complement(14089..14241)
                     /gene="cibB"
                     /locus_tag="VXD01_001440"
     CDS             complement(14089..14241)
                     /gene="cibB"
                     /locus_tag="VXD01_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV0601823.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(14243..14428)
                     /gene="cibA"
                     /locus_tag="VXD01_001441"
     CDS             complement(14243..14428)
                     /gene="cibA"
                     /locus_tag="VXD01_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV0601824.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKVIAGG
                     TALIGSGLAAGYFLGGD"
     gene            14607..15290
                     /gene="tsaB"
                     /locus_tag="VXD01_001442"
     CDS             14607..15290
                     /gene="tsaB"
                     /locus_tag="VXD01_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV0601825.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            15287..15724
                     /gene="rimI"
                     /locus_tag="VXD01_001443"
     CDS             15287..15724
                     /gene="rimI"
                     /locus_tag="VXD01_001443"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV0601826.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQETLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            15714..16724
                     /gene="tsaD"
                     /locus_tag="VXD01_001444"
     CDS             15714..16724
                     /gene="tsaD"
                     /locus_tag="VXD01_001444"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV0601827.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(16764..18070)
                     /locus_tag="VXD01_001445"
                     /pseudo
     CDS             complement(16764..18070)
                     /locus_tag="VXD01_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(18346..18697)
                     /locus_tag="VXD01_001446"
                     /pseudo
     CDS             complement(18346..18697)
                     /locus_tag="VXD01_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18804..19097)
                     /locus_tag="VXD01_001447"
                     /pseudo
     CDS             complement(18804..19097)
                     /locus_tag="VXD01_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            19340..20513
                     /locus_tag="VXD01_001448"
                     /pseudo
     CDS             19340..20513
                     /locus_tag="VXD01_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            20545..21458
                     /locus_tag="VXD01_001449"
                     /pseudo
     CDS             20545..21458
                     /locus_tag="VXD01_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833783.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            21468..23084
                     /locus_tag="VXD01_001450"
     CDS             21468..23084
                     /locus_tag="VXD01_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601828.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT         7350 a         3876 c         4983 g         7045 t
ORIGIN      
        1 gaggtaagac cagactttgt tttaatcgag cagaatattg atgatagttt aaatagctcg
       61 caaccattat ctttatcttt agccatttca gaaatccaac ttttgcttga agtgtatatg
      121 gggatcaaac atgtttcaat taggagataa aaccagaata atatttgcca ttataggggc
      181 aagttgcata ttagtcagta tgtatcttat tccacttatt aaaactgaga ataaattttg
      241 ggaaatactt ttatttatat taggtgtatt gctaattgga attgcgttac taagtcaaaa
      301 aaaataaatt ttgaaatagt attagtgagt tcgcaatcat ttattgctag tggtttagaa
      361 ctgttaagtt tcaaacaata attgatttta aaccttaggt aacctataaa aacaaataag
      421 gtagagaaag gatatcttat ctaggtagct aagtgataaa aacacagtcg tctatcactt
      481 gttaggaaac tatcctaact atgcttaata aaaaaggaga aaataaatgg aactcgtatt
      541 accaaataat tatgttgctc ttgagcaaga agagatgatg tatcttgatg ggggattttc
      601 tattctgaga tggcctgttg caacagccat taatatagct tttaatggtg ttttaggtgg
      661 aggagcaatc agtctagtta gaaattatat tcgtaattat ggtttggggc gagttacaag
      721 cgcaattgct ggagcagctg caagatatgt tggggtacga gttgcaaata gagtggcagg
      781 atttgcactg tctgctatta atggatttgc agcttggatg tcaattggcg atgctattac
      841 aacaatctgg gccaacaatg atgtaaatag gagagaccca aatttaaacg ccttgtggta
      901 actagatatg ggtattaaaa tggaaaaaat ttttgttatt attttttttg tatgtctatt
      961 tatatcatcc ataacttttt tagcctatga ttttgttagc gaagaaataa aaaagttgat
     1021 tatttggatg aatgtcgttt ttttgatttt aatcatagca atgataattt atccaaaatt
     1081 aagaaaatga taaggacact gtaaaattat gatacgtaaa ctaatcattt ttttattaat
     1141 gctccctctt tttgtcttgt ggctagagtt gcatgtccta gtgaataact tactattgaa
     1201 tctagaatct ccccttgatt ttgtgattag tatgagtctt gctttctgta gtttgatttt
     1261 atcaaaaata gttttagaca tactatacgc attgaaagat ttgtacaaga aagaagctct
     1321 tattacgatt tttcctttta tttttatagg caggaagaaa gtaaatgtga ggttctcgcc
     1381 ctatttttca ttccatcgta aaagtttgtc gcctgatgat ttaagatcta ggattatatg
     1441 gagttttatt cttgaaattg ctattatcct agtatttatt ttaaaaattc cttttgtcat
     1501 cattatgctt actacaatat ttttttggaa tataatggat atcaatcatc tcgtttttaa
     1561 taagacggaa tttcttttca atcaaaataa atgggaaaaa gaagattcgt ttgaaagtga
     1621 tttgacaaat acgttaaagg ataaaataca aaaatcagat ctcagttatt ctgacttaat
     1681 gtctcttcag ctgtatgatg cgatgaacca atccaccttt ttaacggata gtgaactctt
     1741 tgaggatatt ctgagtaaaa ttgaagattc tcataacacc cttctgtgta caggtcttgt
     1801 cgagttactg ctgtatgaga tttctattag taacaataac aactggcaag aaaaggttga
     1861 taaaattaga atacagctca tcataataaa tcaattagat tttttctatt atacaagttg
     1921 gttaaggcaa aattttgatt tctgtatgaa tagagagtat cataaaatga aatctcggaa
     1981 attattactg agtaataaaa agatagttta agttcatcct atttgtaaaa caaatgaaac
     2041 aatttcaact aaggaggaga aaacaaatgg aacttgtatt accaaataat tatgttgtga
     2101 ttgatgaaga agaaatgatg tatcttgatg ggggagctta tttaagcaag cgtgcttgtc
     2161 aaggaatttg cgcagcttta gctatgagtc caggaacttt tatagcatta gctggagctg
     2221 cagttttaac caaaaaacta ataaactata ttaaagttgg aggccttgga ggttggctta
     2281 ttggtgcagc agcaggaaaa atagcttact gtattggata tggtgctctt aatagaggtt
     2341 gtgatattag cgggaaccct tatccttggg atggattcat atctgcgaca gtaagatgag
     2401 taatgtagat aagattcgaa aaatacacat tatcgtatgt tggatgtata tatttttatc
     2461 attcagggcg attataaatg acacggagta ttttttgctt atttttttag cttttatcta
     2521 ctcaatagta tcactacctc tatattctgt gaaaaataaa atagtatcta tctgtctagc
     2581 cataaattcg attctgttaa tgagtttccc cattttaatc aataagtttt tcccagaaag
     2641 ttttttgact tataccgtat taataagtgt ttttatccta gagttagcaa tctttcattt
     2701 aattaggaaa gattttgata ttaaattgac taacgaatat aagaaaatta gtcagtttag
     2761 aagcaaggtg tctcaatctc cttggataaa atatttagag atttctagtt ttatattaac
     2821 tatatttcca tctattcttt atggtacagt tgctaatcat gtactgactc ttatcttttt
     2881 gataaaaatt tgtgtagata ccacgataaa atttttattc atcagattat ttgacacaag
     2941 cactttaatg aagaggagaa tattttttct tttcgcattg gatgttatag tttacttatt
     3001 tttaggatat cttttagtga ttcaaaaagc aggctatttg ttttcggttt tacttctttt
     3061 ttctaatttt tcagttccat ttatcaaaga aaaggaatac gaattattta aaaatagcaa
     3121 gtaatagaaa cataggttaa atcttagaac ggcttaaaat cagatatgat aaagggaaat
     3181 agtcttatct aggtaactaa gtgctacaaa cacaatcgag gatcacttgt taggattaca
     3241 ttttaatcat gcttaataag aatggagaat tcctatgggg attgtattac tctgaagttt
     3301 cgaatacctt agttctcgtg attttgagct attctaggtt tagaatcctt cagaatgtaa
     3361 aattttaagc agtcaaagac ttagaatagc ctgaaaacat ttattttgta gcaattctag
     3421 gcttagaatt gctcatatat atgtatttga gctgctcgat agttaggaca gctttattct
     3481 gagaaatctg agctatcaat gcttcagaat agtatttcgc caatggtttt tattgaagag
     3541 gtgattgttt tatgatagtc taaaataaaa ctgatttaat ggagtaaatg gagaatcgtt
     3601 atatgaaaca ttttttttgc aggaattggt gagataaaac ttgttggcta cttattgtat
     3661 atatgtgtag gactagcccc tctttttcat atatatgtca taggttcgga actgagtttt
     3721 gtgaaaatag tgttatctat tttgggagtt atatttgtaa gtatgttaac tattgctcga
     3781 atttatcgga cttttctata aagaatagtt tggacttgaa ctgtatctaa aaacagaggt
     3841 tggtcgatta tcagcctctt tcttgtcgtt gaaaagagtg agatatattg acttttgaaa
     3901 aaaagatgtc ataattgagt tgggataaac ctaaaagtaa tatagtagat tgaatctgga
     3961 atagtccgtt atgactgtta aaatatttct agaaattaat ttgactttcc taatcgattt
     4021 gttcacatct tgtttcaatc tactatactt tctcgttaaa ccgttcggca attcatggtg
     4081 acatggacac atagtagtaa gcacactatg tggcttggca gagctaaaaa ctgttccctt
     4141 gcgataagcc taataagcac aacataggga gttagagaag ccgactctaa tcaaccactt
     4201 tgggcaatag tgagaactgc cccgtgcttt tttattttga gaaaatatgg agtttgtcgt
     4261 tgaaattact tgattgtatt ttggactatc aagaaagatt caatggaaaa acatgtcaag
     4321 tatcaacgaa ttataagtat ttagagattt tcaaagtgaa tttttgtttg actgatttac
     4381 atcatttatt tgacttatac aaaatcacac gagattatgc tagtcaaaca aaacctgcta
     4441 ttcaagctgg tgtttttatt ttagaagatt ttagaaatat cctatgtaca atgatgtaat
     4501 cgaaaggata tctttatatg agtttatcgg tgatattttc tattctaaaa taataagttg
     4561 ttgcatcgta gctagcgatt tatctaaaaa tactatgaaa ttggacgtca tattttttga
     4621 ggataaaaat aaaagatccg cagttttagg tttacgaaga gacaaaagcg gagtatttaa
     4681 accagttact ctacatttta caagcgctaa gaaatatgct aaagttcgta aaacagatgt
     4741 gaaagaaatg aaatggctat aaagattgtc cgcaggctta agcttgcgtt ttttgttgtt
     4801 taacgaaatt aaaaaacaag ctctctcatc ggaaatgttt ttataggaat gaaggaagat
     4861 gatgctatgt ttaaaaagag aatcgaaaag ggcaaaagta gtgtctttat ctttttggag
     4921 tagaagctta tgatatagaa atttgtaata aaaatgtaat ataaaacatt tgacaaatat
     4981 ttacgggggg agtatactta atataagtat agtctaaaaa tgactaccag aaaagaggta
     5041 aatttagatg aataagaaaa aaatgatttt aacaagtcta gccagcgtcg ctatcttagg
     5101 ggctggtttt gttacgtctc agcctacttt tgtaagagca gaagaagctc ccgtagctag
     5161 tcagtctaaa gctgagaaag actatgatgc agcaatgaaa aatgctgagg atgcgaaaaa
     5221 agcagtagaa gatgctcaaa aggctttaga tgacgcaaaa gctgctcaga aaaagtatgc
     5281 cgatgatcaa aagaaaactg aggagaaagc gaaaaaagag aaagaagctt ctaaagcgga
     5341 acaagctgca aatctaaaat atcaacaaga gttggttaaa tatattaaat atatacgtga
     5401 aaataatcca aaaaaaactg aagctcagaa agcaatggat gaggctgaga aagagcataa
     5461 gaaaaaacaa gcagaattta agaaagttag attagaggta attcctagcg cgaaagagtt
     5521 agaagagact agacaaaaag caaaagaagc taaagaaaaa gaaccagaac ttactaaaaa
     5581 agtagcagaa gctaaagcaa aattagaaga agctgagaaa aaagttactg aagccaaaca
     5641 aaaagtggat gcagaacatg ctgaagaagt cgctcctcaa gttaaaattg ctgaattgga
     5701 aaatcaagtt cataaactag aacaaaagct caaagagatt gatgagtctg attcagaaga
     5761 ttatgttaaa gaaggtctcc gtgctcctct tcaatctgaa ttggatacca aaaaagctaa
     5821 actattgaaa cttgaagagt tgagtggtaa gattgaagag ttagacgctg aaattgcaga
     5881 acttgaagtt caacttaaag atgctgaagg aaacaataat gtagaagcct actttaaaga
     5941 aggtttagag aaaactactg ctgagaaaaa agctgaatta gaaaaagctg aagctgacct
     6001 taagaaagca gttgatgagc cagaaaaacc agctgaagag tctgagaatc cagctcctgc
     6061 accaaaacca gctccagctc ctgcaccaaa accagagcaa ccagctccag ctcctgcacc
     6121 aaaaccagag aagtcagcag atcaacaagc tgaagaagac tatgctcgta gatcagaaga
     6181 agaatataac cgcttgactc aacagcaacc gccaaaagca gaaaaaccag ctccagctcc
     6241 tgcaccaaaa ccagagcaac cagctcccgc accaaaaacg ggctggaaac aagaaaacgg
     6301 tatgtggtac ttctacaata ctgatggttc aatggctaca ggttggctac aaaacaacgg
     6361 ttcatggtac tacctcaaca gcaatggcgc tatggctaca ggttggctcc aatacaacgg
     6421 ttcatggtat tacctaaacg ctaacggcgc tatggcaaca ggttgggcta aagtcaacgg
     6481 ttcatggtac tacctaaacg ctaacggttc aatggcaaca ggttgggtga aagatggaga
     6541 tacatggtac tatcttgaag catcaggtgc tatgaaagca agccaatggt tcaaagtatc
     6601 agataaatgg tactatgtca acagcaatgg cgctatggcg acaggatggc tccaatacaa
     6661 tggttcatgg tactacctca acgctaacgg tgctatggca acaggttggg ctaaagtcaa
     6721 cggttcatgg tactacctaa acgctaacgg ttcaatggca acaggttggg tgaaagatgg
     6781 agatacctgg tactatcttg aagcatcagg tgctatgaaa gcaagccaat ggttcaaagt
     6841 atcagataaa tggtactatg tcaatggctt aggtgccctt gcagtcaaca caactgtaga
     6901 tggctataaa gtcaatgcca atggtgaatg ggtttaagcc gattaaatta aatcatgtta
     6961 agaacatttg acattttaat tttgaaacaa agataaggtt cgattgaata gatttatgtt
     7021 cgtattcttt aggtacctat cttatgattt caggaaatgt cattaaaaaa acgactcctt
     7081 ttctctaact tgaaaaatag attagagaaa atgggttgtt ttatttatta tagttatttg
     7141 aatgaagata agaataaggt atactcacat cattcacata atctgtatat tgactataag
     7201 ttttaaaaaa caatttttaa gctcttcctt gtcttctcta accaagcgtg ttataatgaa
     7261 tactgctcaa gcgaccttca atcgtgaagc acacacgacc ttcaatcgtg aataaacgaa
     7321 tagatgggag acttaccatg agtgataact ctaaaacacg tgttgtcgtg gggatgagtg
     7381 gtggtgttga ttcgtcggtg acggctcttt tgctcaagga gcagggctac gatgtgatcg
     7441 gtatcttcat gaagaactgg gatgacacag atgaaaacgg cgtctgtacg gcgaccgaag
     7501 attacaagga tgtggttgcg gtggcagacc agattggcat tccctactac tctgtcaatt
     7561 ttgaaaaaga gtactgggac cgcgtttttg agtatttcct agcggaatac cgtgcagggc
     7621 gcacgccaaa tccggacgtt atgtgcaaca aggaaatcaa gttcaaggcc tttttggact
     7681 atgccataac cttgggggca gactatgtag cgactgggca ttatgctcga gtggcgcgtg
     7741 atgaggatgg taccgttcac atgcttcgtg gcgtggacaa tggcaaggat cagacctatt
     7801 tcctcagcca actttcgcaa gaacaacttc aaaaaaccat gttcccacta ggacatttgg
     7861 aaaagcctga agttcgaaaa ctagcagaag aagcaggtct ttcgactgct aagaagaaag
     7921 actcgacagg gatttgcttt atcggagaaa agaactttaa aaactttctc agcaactacc
     7981 tgccagctca gcctggtcgc atgatgactg tggatggtcg cgatatgggc gagcatgcag
     8041 gtctgatgta ctatacgatt ggtcagcgtg gcgggcttgg tatcggtggg caacacggtg
     8101 gtgacaatgc cccttggttc gttgtcggaa aagctctaag caagaatatt ctctatgtag
     8161 gacaaggatt ctaccatgat tcgctcatgt caaccagcct agaggctagc caagtccact
     8221 ttacttgtga tatgcccgag gagtttacgc tagaatgtac ggctaaattc cgttaccgtc
     8281 agcctgactc taaggtgacc gtccatgtca aaggagacaa ggcagaggtc atctttgcgg
     8341 aaccacaacg cgccattaca ccaggacagg cagttgtctt ttacgatggc gaagagtgtc
     8401 taggtggcgg tttgattgac aatgcttacc gcgatggaca agtttgtcag tacatttaga
     8461 ttgacaaatt ttctcaattt gctacaataa taacagcaat agaaatgatg gtcaaagctc
     8521 atggatgttg caggcttttt tgtcctgcac ttctttgtag ttttgactgt ttttgtgtcg
     8581 tttaagggaa aggacaagaa tgactcaaca agactttcgg acaaaagtag acaatacggt
     8641 ttttggtgtt cgggcgacag ccttgattgt ccaaaatcac aagcttctag ttaccaaaga
     8701 caagggcaag tattacacta ttggaggtgc gattcaagtc aatgaaagca cggaagacgc
     8761 ggtagtccgt gaagtgaggg aagaactggg tgttaaagct caagctgggc agctagcttt
     8821 tgtggttgaa aatcgttttg aagtggacgg cgtttcctat cacaatatcg agtttcatta
     8881 tctggtggat ttgcttgaag atgccccgtt gaccatgcag gaagatgaga aaaggcagcc
     8941 ctgtgagtgg attgacttgg ataagcttga ggatatccag ctagttccag cctttttaaa
     9001 aacggcccta ccagattggg aaggccaact aagacacatt catcttgagg aataggagag
     9061 aaacatgact tatcatttta ctgaagaata cgatattatt gtaattggtg cgggacacgc
     9121 tggggttgag gcttccttgg ccgctagccg tatgggctgt aaggtcctgc ttgcgaccat
     9181 caatattgaa atgctggctt tcatgccttg taatccctct atcggtggtt ctgccaaggg
     9241 gattgtcgtg cgtgaagtcg atgccctcgg tggcgagatg gccaagacta ttgacaagac
     9301 ttacatccag atgaagatgc tcaacacagg gaaggggcca gctgtccgtg ctcttcgtgc
     9361 gcaggctgac aaggaacttt actctaagga gatgcgcaag acagttgaaa atcaagaaaa
     9421 tctgaccctt cgtcaaacca tgattgatga gattttggtg gaagatggca agattgtcgg
     9481 tgtgcgtaca gccacccatc aagaatatgc tgctaaggct gttattgtga cgacagggac
     9541 tgctctccgt ggggaaatta tcatcggaga cctcaagtac tcatcaggtc ctaaccacag
     9601 cttggcttct attaacctag ctgacaatct caaggaactg ggcctcgaaa tcggtcgttt
     9661 caagacagga acccctccac gtgtcaaggc ttcttctatc aattacgatg tgacagaaat
     9721 ccaaccagga gatgaagcgc ctaatcactt ctcatacact tcacgtgatg aggattatgt
     9781 caaggaccaa gtgccatgct ggttgaccta caccaatggt accagtcatg agattatcca
     9841 aaacaacctc caccgtgcgc ctatgtttac aggtgtggtc aagggagtgg ggcctcgtta
     9901 ctgtccgtcg attgaagaca agattgtgcg ctttgcggac aaggaacgcc accaactctt
     9961 ccttgagcca gaaggacgta atacagagga agtctatgtg caaggcctct caaccagtct
    10021 acctgaggat gtccagcgtg acttggttca ttccatcaaa ggtttggaaa atgcagagat
    10081 gatgcgaaca ggttatgcca ttgagtacga catggtcttg cctcatcagt tgcgtgcgac
    10141 tttggaaacc aagaaaatct caggtctctt cactgctggt cagacaaatg gaacatcagg
    10201 ttatgaagaa gctgctggcc aagggattat cgcgggtatc aatgcggctt tgaaaatcca
    10261 aggcaagcct gaattgattc taaaacgaag tgacggttat atcggggtga tgatcgacga
    10321 cttggtgacc aagggaacca ttgaacctta ccgtctcttg accagtcgtg ctgaataccg
    10381 tcttattctt cgccatgaca atgctgatat gcgcttgact gagatgggac gcgagattgg
    10441 ccttgtggac gatgaacgct gggctcgttt tgaaatcaag aaaaatcaat ttgataatga
    10501 gatgaaacgc ctagacagta tcaaactcaa gccagtcaag gaaaccaatg ctaaggttga
    10561 ggaaatgggc ttcaagccgt tgacagatgc ggtgacagcc aaggaattcc ttcgccgtcc
    10621 agaagtttct taccaagatg tggtggcctt catcggacca gctgcagaag acttggatga
    10681 caagattatc gaattgattg aaacagaaat caagtatgaa ggctatattt ccaaagccat
    10741 ggaccaggtt gccaagatga aacgcatgga agaaaaacgc attccggcca atatcgactg
    10801 ggatgacatt gattctatcg caaccgaagc ccgtcagaag ttcaaactca tcaatccaga
    10861 aaccatcggc caagccagcc gtatttcggg agtaaaccca gcagatattt ctattttgat
    10921 ggtgtatctg gaaggtaaaa atcgtagtat ttctaaaact cttcaaaaat caaaatgata
    10981 cgtcgtcggc ttcttacgaa tgagttcaaa gcttggcttt gattcatctc cagcctccca
    11041 tagtttcccg aactatggga gctaactcaa gttatgcttt cgcttagcct tctagtctga
    11101 ttttcattga gttttaatct caaaagaaag catagagaaa aacagctccg aagacggggc
    11161 tgttttgttg acttgtactc aatgaaaatc aaagagcaaa ctaggaagct agccgtaggt
    11221 tgctcaaagc actgctttga ggttgtagat agaactgacg aagtcagctc aaaacacagt
    11281 tttgaggttg tggatagaat tgacgaagtc agtaacatat atacggcaag gcgaagctga
    11341 cgtggtttga agagtattat tcttcatctg gtgtgaggat catcgggatg atgatcggtt
    11401 cacgttcggt attttcatag aggaaggggc gaatagcgtt gacaatggca ccattgacag
    11461 attgcacgct agcatcctta tttttcagtg cgatacgaat ggcattgaag aggatacgct
    11521 ggctttggcg aatcaagtcg ccagactctc tcatgtagac aaagcctcgg ctgaggatgt
    11581 ctggaccaga tagaatcatc tgcgatttga agtcaacagt tgcgactgcc agaacgacac
    11641 cgtcttcaga tagatcgcga cgatctttga ggacagctgc gccaatttca ccgatacgat
    11701 ttccatcgac atagatatct tgggcgttga aatgacctgc gatacgagct gagtcagcag
    11761 taagggcaag cacatcgcca ttgctcatga taaagatatt gtccttctca acaccagtat
    11821 ccactgctag tccagcgtgg actttttgca tgcggtattc accgtggaca ggcatgaagt
    11881 attttggctt aatcaagcag agcatgagtt tttgctcttg ctgaccaccg tgtccagatg
    11941 tatggatatt gttcacttta ccgtggataa cttcgacacc agcttcagaa atgatgttaa
    12001 tcagcttgtt gacgctagta gtgtttccag ggatgggact agaagagaag ataacggtat
    12061 cacctggttg taattgtact tgacggtggg ttccgttggc gatacgagag agggctgcca
    12121 taggctcacc ctgactacct gtacagagga taagaacttc tcctgcagga taatctttga
    12181 tttcatttgg ctcgataaag gttcccttag gggctttgat gtagccaaga tcgattccgt
    12241 tgacaatggc cttttccata gaacgaccaa agaccgcaat cttgcgtcca gtcttaacag
    12301 cagcttctgt tgcctgctgg agacggaaga tatttgaggc aaaggatgca aagatgatac
    12361 gtccttcaat accttggata atcttcataa tggactgacc aacgactttt tcagagttgg
    12421 taaaggttgg tacttccgca tttgtcgagt cagacaggag acagagcacg ccttcttcac
    12481 caagcgcagc catacgatgc aagtccgcag gttctccaac tggagtaaag tcgaacttaa
    12541 agtcacccgt acagacgatt ttcccttgag gagtatgaat gacaatcccc aaaggctctg
    12601 gaatagagtg agtcgttcta aagaaagttg ccttgagatt tttaaaggtc aactcggtgt
    12661 tgtggttgat ttcgtaaagt ttggcgttgc gcaagaggcc gtgttcttcg agtttcccac
    12721 ggatcaaagc caaggcaagc ggtccagcgt agatagggac atttgcttgc ttgagtagga
    12781 acggaatccc accaatgtgg tcctcgtgtc cgtgtgtgat taaaacagcc ttgacgcggt
    12841 cgatattgtc cacgatgtaa gagtagtcag gaatgacata gtcgatacca agcaagtcat
    12901 cttctgggaa tttaatccca gcatcgacga tgataatctc gtcttggtat tcaattccgt
    12961 aagtgttttt cccgatttct cctagaccac cgatggcaaa aacgccgact tcttcaggtt
    13021 taagagtgta ggccatatta gaactccgta atttcgaagg cgccagtttc tttttcgtaa
    13081 tcgagcaatt tgtcagacaa gagttcgata tattcgatat tgtactctgg gcgattttct
    13141 tcgacaagtt ggcgagcagt gatacggccc tcaagttctg agctggtatc gatatctaag
    13201 taaagcgcgc gtgttgtttc acggcgtggg ctacgttctt ttgtttcttg ataaaaaact
    13261 ttgtaaatca tatagttcct ttctatttac aggtcagctt attccaaact tttagcagat
    13321 atttgcttga tttcattcca ttttgtgtct agattgacct tgattcgtta caattatttc
    13381 aattatacca caaaatgaaa aattagtaaa agacggaaac gagaaagtta ggggacgatt
    13441 tctttggtaa gcgtttgcaa aaacaaagaa aatgtattat gttgataacg gaagtgaaat
    13501 ttattgcttg tcataattcc atatagattt taagtcaagg aggttgccct atgtataact
    13561 tatttgcttt tgctatcgga gctcgcttgg tagcttttat tgtttttgtt gcttgcgttt
    13621 atgcggggaa tcttctattt gccaaactgg aacgacgaca aaccaagttc ttgtggaaaa
    13681 tgacctttgt gactctctac tcgctttttc tcctcctcgt gacctatgtc gtttggtttg
    13741 tattttactt tgaattaaat gcttagatgc cctgcttatg ctggggtttt ttgtttgggg
    13801 atgtagagat agtagattta cgacacgaaa attccacccc atctatcaag atgaggtggt
    13861 ctttgcattt ttctaacatg acatgacaat ggaattttca aagcttatta tttttatggg
    13921 agtcattgtt ctgatcaaaa atagagttga agcataaaaa taaaacaata caaacagata
    13981 aatcgaatgg taaagggatg gtagtaatgt tcaaatcatt gagaatgctg agcaaactgt
    14041 aagagatgaa gacaataaaa tttatccttc taaaaatgtg tttcttatct agcatgactt
    14101 accaaacttt ttacgaaggt cttttccaat ggtataacct gccataaata aagcgatacc
    14161 aacaccgaca ccaaagccac ccttgatttc ttgcaattcc ttattagaaa tttcacgata
    14221 attgttcaaa tctttcatca tattaatctc ctcctaaaaa ataaccagct gccaaaccag
    14281 aacctataag tgctgttcca cctgcaataa ccttccaaga tactgctact ccaaagataa
    14341 ctaagggagc gagaccgcca tcaatatctg ataattcatt ttcagataag gataaaaatt
    14401 gattgtcaag aatgtcaaaa tttgtcattg aactttcctc cttttttctt gttcactttt
    14461 atattcggaa aagaaaagga aaattgagca ttttttttaa attattttta gttaagtgag
    14521 ggcactcttg tctgggggca aagaaaattc ccatgtgcca gcttttgtag tataatagta
    14581 agcagacaaa aagataggaa tgtgttatga aagtattagc ttttgatacg tccagcaagg
    14641 ctctttctct ggctatttta gaggataagc aggttcttgc cgagacgacg attaatatta
    14701 agaaaaatca cagtattacc cttatgcctg ccatcgattt tttgatggca agtttggatt
    14761 ggacacccaa ggacttggac cgaatcgtgg tagctgaagg gccgggtagc tatacaggct
    14821 tacgaatcgc ggtagccact gccaaaactc tggcttatac tctgaatatc gagttggttg
    14881 gtatgtcgag tctcttggct ctggtgccct accaacaaga aggtttgttt gtccccttga
    14941 tggatgcgcg tcgcaataat gtttatgcag gattttatga aaatgccaaa cctgtcatgg
    15001 cagaagcaca tctgcctttt gagcgagtca ttgagctaat caagggcgct agtcaggtaa
    15061 cctttgtcgg agaagttggc ccctttgttg agcagattca aaaacacttg ccaaggactg
    15121 attacaaaga aacattgccc aatgcagcta atctagctct tttggcctgg gacaaggaag
    15181 cagactcctt gcatgatttt gtgccaaatt acctcaaacg tgttgaggca gaggaaaact
    15241 ggctcaagaa ccataccgag tctggtgagt cctacattaa acgcctatga tagaaatcaa
    15301 gcgaattcaa caacagcctg acctagctca agccatctac gctgttatgg cagctgttta
    15361 cctagtcagt ccttggactc tggagcaaat ccaagcagat ctgtcccaag accagacttg
    15421 gtatgcattg gcttatgatg gggcagaagt gattggattt ctagctgtgc aggagactct
    15481 ctttgaagca gaagtcctgc aaatcgctgt caaaggagct tatcagggtc agggaattgc
    15541 gtcagccttg tttgctcaat tgccgacaga taaggagatt ttcctcgaag tcagaaagtc
    15601 aaatcaacga gcgcaagcat tttacaagaa agaaaaaatg gcggtcatcg ctgagcgaaa
    15661 ggcctactac catgacccag tcgaggacgc cattatcatg aagagagaaa tagatgaagg
    15721 atagatatat tttagcattt gagacatcct gtgatgagac cagtgtcgcc gtcttgaaaa
    15781 acgacgatga gctcttgtcc aatgtcattg ctagtcaaat tgagagtcac aaacgttttg
    15841 gtggcgtagt gcccgaagta gccagtcgtc accatgtcga ggtcattaca gcctgtatcg
    15901 aggaggcatt ggcagaagca gggattaccg aagaggacgt gacagctgtt gcggttacct
    15961 acggaccagg cttggtcgga gccttgctag ttggtttgtc agctgccaag gcctttgctt
    16021 gggctcacgg acttccactg attcctgtta atcacatggc tgggcacctc atggcagctc
    16081 agagtgtgga gcctttggag tttcccttgc tagccctctt ggtcagcggc ggacacacag
    16141 agttggttta tgtttcggag gcaggagatt ataagattgt tggggaaacc cgtgatgatg
    16201 cggttggtga ggcttatgat aaggtcggcc gtgtcatggg cttgacctat cctgcaggtc
    16261 gtgagattga cgagctggct catcaggggc aggatattta tgatttcccc cgtgccatga
    16321 ttaaggaaga taatctggag ttctccttct caggtttgaa atctgccttt atcaatcttt
    16381 atcacaatgc cgagcaaaag ggagaaagcc tgtctacaga agatttgtgt gcttccttcc
    16441 aagcagcagt tatggacatt ctcatggcaa aaaccaagaa ggctttggag aaatatcctg
    16501 ttaaaaccct ggttgtggca ggtggtgtgg cagccaataa aggtctcaga gaacgcctag
    16561 cagccgaaat cacagatgtc aaggttatca tcccccctct gcgactctgc ggagacaatg
    16621 caggtatgat tgcctatgcc agcgtcagcg agtggaacaa agaaaacttc gcaggctggg
    16681 acctcaatgc caaaccaagt cttgcctttg ataccatgga ataaagagtg gctctttgtc
    16741 aagtgtagtg ggtaggcgaa aagctacaat ctggagagta cgaaattcgt actctctttt
    16801 ttgatgttca aagtcatcaa aatccgtttt ttaaaattgt taaagttccg gaaaccaaag
    16861 gctttgcgct tgataacctt aatcaaatta ttggtcgctt caagtttagc gttggaataa
    16921 ggcagcttaa gtgcgttgat aatcttatct ctatccctta aaaaagtcca aaagaccgtt
    16981 tgaaaaagcg gatgaaccgt tggcagttct tgctcaatca atccaaagaa atggtcggca
    17041 ttcttctctt gaaaatgaaa gagcaggagt tgatagagtt cgtagtgaac ctgtaatccc
    17101 tcagagtagg aaagcagctt atctcgtact tcccgatggg ttaagtgcat tcgaaacgtg
    17161 gactgataga atcgtttctg acagagcttg aagctatcct ggtgtagtaa atcagtccag
    17221 tggactgatt tagcccgagc ctagaaacga aaaagcgagg gttccaaaag cgcttgagcg
    17281 cccgatactc caaggatttt cggtcaaatt ggttcatgat ttggattcgt actcggttca
    17341 tagctcggct cagatgttgg acaatgtgga agcggtcaag aacaatcttc gcctttggaa
    17401 agagttgctt agcgagccga taataagggc tgtacatgtc catggtgatg acctcgacca
    17461 gctcccgaac ctctctctga tagcgttgga aatggtttcg aatcaccgca tgagttcgcc
    17521 cgtctaaaat tgcgaggatg gatttggact caaaatcttg ggcaatgaag ctcattttgc
    17581 tctttttgaa gctatactca tcccaactca taacttttgg caacttggtc caatcggttt
    17641 caaacttaaa ttccctcagt tttcggatga cggtggaagt tgagaccgcc aatctgtggg
    17701 caatctcagt catagactgc ttttcaagga ggagctgagc gattttttgt ctcaccatgt
    17761 tggaaatctg gcaatttttc ttgacaatgg atgtttgaga aacgaccacc ttaaggcaat
    17821 tcttgcactg aaagcggcgc tttttgagat gcagtaccgt gggtaaaccc tgacagtcga
    17881 gaagcggaat tttagaggct ttctggaagt cgtatttgat catcttccct tgacaatgag
    17941 gacaaggagg agcgggggaa tccaactttg cctgaacgac tagatgggtt tggtatttca
    18001 gaacagacaa gattttgata tttttgtctt ccaatccgag caaatctgtg gtattcttaa
    18061 gttgttccat atggaccctt tctaatgagt tggttagacg cttttcatta taggtcatat
    18121 ggggcttttt ttctacaaga aacgacccta taattcctgg ggtgggatta cccactacag
    18181 aaattataga gccaaagcat tccaaagtct tgtctgactc tggaatgttt tctgttcaca
    18241 gttgttttgt aactgcctaa taagtaaccg cgctataacg aggtatctac cgagattgtc
    18301 aattctccag tatactgtta taaaaaacaa aactggagga tttttttatg tccccccatc
    18361 gtcccatcga ctgttccgta gctgcccaat aacggagtat agtcggctga aacaagaata
    18421 ggacaaaagt gcctcaagaa aagcatcgta atttgacaat attattctga gatgtttttg
    18481 atgtaagccc atattttctc aatgggatta tactcgggtg aataggtagg aagtggtaac
    18541 agtctatgcc ctgctcctta cacatgttca ttctgtgaaa ccttgcattg tccataatga
    18601 taagggatgg tgtatctaaa gtaggtagta agaatttttg gaagcaagct tcgaaaaagt
    18661 cactcgtcat cgtatcttta taggtcatcg gagccatagt atattgaaac aaaaaagggc
    18721 attagtactt ctataacagt atcgcaatct ctggtgtgcg ttgtctcgat cttaattcaa
    18781 ataattatat cttcttccag agagactaac tgcctgctca aggctcgatc atattcgaga
    18841 taaaaatagg tctcaacccc tgtctcataa atataaatag gagtcaggta gcttaagtga
    18901 ttcaattctt taaggaaccg atttactttt tctgggtctt gttcgcagta ggtacggctc
    18961 ttttttagac tatatcccat agcctttaga gcgtaatgaa tagttgttgg aggacagttg
    19021 aattcagcag ctatttcagt caaataagca tcgggatgag tttcaatata gatctttaat
    19081 ttatctctat caactttttc aattaatagt ggaagttttc ttaaagttag tgtgttgaaa
    19141 cgtttttata cagtgctaaa atttgaagtg tagtgcagat gtatttgtaa tagtattata
    19201 gcaattcttt ggagaaggtc gagacaagag aaaataggta tctttgagat ataagcatga
    19261 tttactataa aattattgag ttattcataa aaatttctct atcaaatatc ataatgcgtc
    19321 gtttaaggag atggttacaa tgcaatatag ttgtggaaaa ataaatatta atatccctga
    19381 tggatatgga gacattaagg atatagtgtt ttcggctcat attatagtta ggtataataa
    19441 tggacattgt ggaggtatag atccgcatat aattggactt tgtaaaaagc agatcagaag
    19501 gatgtctcta tatcctattt tgataatcgt atctagagat tcaaaggtta ttgatgatta
    19561 taaaaattta gatattgcct atgttgattg tactcaatgt tcaaataatt ttgaaactgc
    19621 cttacacgtt aaaaatattt taaaattatt aaaaatccaa cttatacact gtcatggcta
    19681 ctcaactaat tattttttat atatgttaaa aaaacttgac aagaatggat ttggaaaggt
    19741 taagacagtg ataacatgcc atggatgggt tgaatataac ttaaaaaaga aattcttgac
    19801 ttattttgat ttttggacat attctatggg agatgctttt atttgtgtat ctgaaactat
    19861 gaaaaaaaga ttggagagta taataaaaaa ataagaagat agttgcaata aataacggaa
    19921 ttaatgtatc aaatagcgat ttagatgtag taggtgttca agactttaaa aaagaatttt
    19981 gtattccaaa taacaaaaaa atcatttgtt atttggaagg ttggatccag aaaaaaggcc
    20041 ggatagattc cttgaatttg cagaaaaatt atttttagtc agagaagatg tgatttttat
    20101 tatggctgga aatggtagta tgtgggctgc tttgaaagaa aaaatttgcc atttgaaatg
    20161 tagagataat ttcaggttac ttggtgaaat ctatccagct actatagttt accaaatatc
    20221 ggatttattg tatattcctt ctgatacaga aggaatacct atgtgtgttt tagagtcaat
    20281 gtcacaagga actccggttt tagctagtaa tgttggcggg ttaagtgaaa ttattgaaca
    20341 tagggttgat ggatttttat ttgagaagga agatgttgag ggagtgtgtg cttgtgctaa
    20401 ttttttactc aatgattctg agtatttgaa atatataggt gagaatagta aatcaaaaat
    20461 aagaaaacat gagagtatat gatgaattat tagagaagag tagtcatgga taggaatata
    20521 gattaagaat tagtaagtat tataatacca acacataata ggtatgaatc tctgattaga
    20581 gctgtgaaaa gttgtttaca tcaaagttat aaaaatatcg aagttataat tattgatgat
    20641 aattatagta atgtaaattt aagaaataaa attatccatc aatttggcta taccaatcat
    20701 agaattaagt taattttaag taatgaagat ttaggtgcaa ctaatgccag aaacataggt
    20761 atcaaaaatt ctagaggtaa gtatatatca tttttagacg atgatgatga atatatgcca
    20821 gatcgaattt ttaagttgat ggcttgtttt aaaaagagta gaatgaagaa tttagcttta
    20881 gtttatagtt atggaataat aatttatcca aatggtacac gagaagagga gaagaccgat
    20941 tttgttggaa atcccttgtt tgttcaaatg gttcacaata tagcaggtac gtcattttgg
    21001 ttgtgtaaaa aagaggtgct agaattaatt aatggttttg agaaaataga ttcacatcag
    21061 gacggtgttg ttttattaaa actacttgct caaggatacc aaattgatat agtgcgagaa
    21121 ttcttggtga attactacgc tcacagtaaa gaaaacggta tcactggagt gacacaaaaa
    21181 acaattaatg cagatgaaga atattataat tactgtagga aatattttaa tttattgagt
    21241 ttcaacgaga gaatattggt tacaaagaaa tattattctt taaacataaa gcggttacta
    21301 ttaataggag acaaatgcaa ggctttaaaa gtaatcaaga aggcaagaga agaaaaaatt
    21361 tttaacgaat ttcttttttg aaatatatgt tattatatca ttttggcttt ttctattgta
    21421 tatatgacaa ctatgttcaa ttaaaattta gaaagtgaga aactattgtg tatactatta
    21481 taaaatcaaa tataaaaaaa tttagtttat taacgatatt tattgttgct ggtcaattat
    21541 tgctaattta tgcagcaact attaatgctc tggtgttgaa tgaattaatt gcgatgaatt
    21601 tagagcggtt tttgaaattg tcaatctacc aaatgattgt ctggtgtggg ataatattcc
    21661 ttgactgggt agtgaaaaat tatcaggttg aagtgatcca agagtttaat ctagagattc
    21721 gaaatagagt tgccacagac atctctaact ctacctatca agaatttcat agtaaatcat
    21781 caggaacata tctttcgtgg ctaaataatg atgttcagac tttaaatgat caggctttta
    21841 aacaactttt tttagtaata aaaggaattt ctggtactat atttgcagtt gtgactctta
    21901 atcactatca ttggtcattg actgtagcca ccttgttttc attaatgatt atgctacttg
    21961 taccaaaaat ctttgcatcg aaaatgcgag aagttagtct aaatttaact agccaaaatg
    22021 aagctttttt aaaatctagt gagactatat tgaatggatt tgatgtgtta gcgtccttga
    22081 atcttttata tgtattgcct aagaaaatta aagaagcagg aattttatta aagatggtta
    22141 tacaaagaaa gacaactgta gaaacgttag caggcgctat tagcttcttt ctcaatattt
    22201 tttttcagat atctctcgtt tttttaacag gctatcttgc aataaaagga atagtgaaaa
    22261 ttggtactat tgaagcaata ggagcactaa caggtgttat ttttacagcg ctaggtgaat
    22321 taggaggtca attatcctct attattggta cgaagcctat ttttttaaaa ttgtattcaa
    22381 ttaatccaat tgagtcaaat aaaatgaatg atatcgaacc aaatgaggtg aatagagatt
    22441 ttccgttata tgaagcaaaa aatatttgct ataagtatgg agataaagaa atattaaaaa
    22501 acttaaattt ttgttttcaa cgtaatgaaa agtatttaat tttaggtgaa agtggaagcg
    22561 ggaaatctac attattaaaa ttattgaatg gctttttgag agattatagt ggagaattgc
    22621 gattctgcgg ggatgatata aaaaaaacct cctatttaaa tatggtttcg aatgttctat
    22681 atgtagatca aaaagcttat ttgtttgaag gtacgattag agataatatt ttattggaag
    22741 aaaattatac tgatgaagaa atactacagt ctttagagca agttggtttg agtgtaaaag
    22801 attttcctaa taacatttta gattattatg ttggtgatga tgggagatta ctgtcaggag
    22861 ggcagaaaca aaaaattact ttagctagag ggctaattag aaataagaaa atagtattaa
    22921 ttgacgaggg aacttctgct atcgatagga gaacttcgtt agcgattgaa cgtaagatat
    22981 tagatagaga ggatttgact gtcattattg ttacccatgc tccgcatccg gaacttaaac
    23041 aatattttac taagatatat caatttccaa aggattttat ttaagaatat aggggaggga
    23101 aacatgagat tctattgtga agcttatgag gtaattactg aagagaaaaa agtatcattt
    23161 ttttatgtag atgaaaaacc cttaaggtat ctgttatttg actatatatt tctactagtt
    23221 ctagctaaaa aaaaatatcc caatcttatg aact
//
LOCUS       DAVLDI010000037        21783 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLDI010000037 DAVLDI010000000
VERSION     DAVLDI010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21783
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.037"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..235)
                     /locus_tag="VXD01_001451"
     CDS             complement(<1..235)
                     /locus_tag="VXD01_001451"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0601829.1"
                     /translation="MTLRTEDQVRDYAREVLGFNEVEENINQGTGQITTFNQLGFKGY
                     SDKPDGWYLPKNMNDVAIILETKSEERDISKQIF"
     gene            complement(239..457)
                     /locus_tag="VXD01_001452"
     CDS             complement(239..457)
                     /locus_tag="VXD01_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0601830.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(748..981)
                     /locus_tag="VXD01_001453"
     CDS             complement(748..981)
                     /locus_tag="VXD01_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HEV0601831.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDKEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAVYSIHFNNGYCN"
     gene            complement(1195..2826)
                     /gene="rlmD"
                     /locus_tag="VXD01_001454"
     CDS             complement(1195..2826)
                     /gene="rlmD"
                     /locus_tag="VXD01_001454"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0601832.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKNS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSEQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2900..3874)
                     /locus_tag="VXD01_001455"
     CDS             complement(2900..3874)
                     /locus_tag="VXD01_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV0601833.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3948..4562)
                     /gene="pmp23"
                     /locus_tag="VXD01_001456"
     CDS             complement(3948..4562)
                     /gene="pmp23"
                     /locus_tag="VXD01_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV0601834.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     QDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4562..5536)
                     /locus_tag="VXD01_001457"
     CDS             complement(4562..5536)
                     /locus_tag="VXD01_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV0601835.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDVSRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(5544..6800)
                     /locus_tag="VXD01_001458"
     CDS             complement(5544..6800)
                     /locus_tag="VXD01_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV0601836.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYISLIEPGDTVMGMDLASGGHLTHGAPVSFPGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6862..7293)
                     /locus_tag="VXD01_001459"
     CDS             complement(6862..7293)
                     /locus_tag="VXD01_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0601837.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7295..7894)
                     /locus_tag="VXD01_001460"
     CDS             complement(7295..7894)
                     /locus_tag="VXD01_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV0601838.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFDQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7881..8720)
                     /gene="prmC"
                     /locus_tag="VXD01_001461"
     CDS             complement(7881..8720)
                     /gene="prmC"
                     /locus_tag="VXD01_001461"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV0601839.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTFKDQFGQDRMVVVDD
                     GQD"
     gene            complement(8720..9799)
                     /gene="prfA"
                     /locus_tag="VXD01_001462"
     CDS             complement(8720..9799)
                     /gene="prfA"
                     /locus_tag="VXD01_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV0601840.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASTR
                     DTVTAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9816..10289)
                     /locus_tag="VXD01_001463"
     CDS             complement(9816..10289)
                     /locus_tag="VXD01_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0601841.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKKYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTASAGLGNKLWLSYEPENEHARSCYLSYGFKETGEIYENEVVAIYDFNN"
     gene            complement(10279..10878)
                     /locus_tag="VXD01_001464"
     CDS             complement(10279..10878)
                     /locus_tag="VXD01_001464"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV0601842.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGFIRDLPETPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            11002..11184
                     /locus_tag="VXD01_001465"
     CDS             11002..11184
                     /locus_tag="VXD01_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV0601843.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            11322..12695
                     /gene="mnmE"
                     /locus_tag="VXD01_001466"
     CDS             11322..12695
                     /gene="mnmE"
                     /locus_tag="VXD01_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV0601844.1"
                     /translation="MITREFDTIVAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIVDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPEAIETSELPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNEGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12742..13677)
                     /gene="dapA"
                     /locus_tag="VXD01_001467"
     CDS             complement(12742..13677)
                     /gene="dapA"
                     /locus_tag="VXD01_001467"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV0601845.1"
                     /translation="MSYQDLKKCKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLVYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFIAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13733..14809)
                     /locus_tag="VXD01_001468"
     CDS             complement(13733..14809)
                     /locus_tag="VXD01_001468"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV0601846.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(15395..15467)
                     /locus_tag="VXD01_001469"
     tRNA            complement(15395..15467)
                     /locus_tag="VXD01_001469"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15432..15434),aa:Thr,seq:ggt)
     gene            complement(15567..16076)
                     /locus_tag="VXD01_001470"
     CDS             complement(15567..16076)
                     /locus_tag="VXD01_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV0601847.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(16074..16170)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            16199..16630
                     /locus_tag="VXD01_001471"
     CDS             16199..16630
                     /locus_tag="VXD01_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV0601848.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            16712..17089
                     /gene="mscL"
                     /locus_tag="VXD01_001472"
     CDS             16712..17089
                     /gene="mscL"
                     /locus_tag="VXD01_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV0601849.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(17131..18225)
                     /gene="hemH"
                     /locus_tag="VXD01_001473"
     CDS             complement(17131..18225)
                     /gene="hemH"
                     /locus_tag="VXD01_001473"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV0601850.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTIRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            18380..19603
                     /gene="pepT"
                     /locus_tag="VXD01_001474"
     CDS             18380..19603
                     /gene="pepT"
                     /locus_tag="VXD01_001474"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV0601851.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLIDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(19639..20268)
                     /locus_tag="VXD01_001475"
     CDS             complement(19639..20268)
                     /locus_tag="VXD01_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601852.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            20233..20454
                     /locus_tag="VXD01_001476"
     CDS             20233..20454
                     /locus_tag="VXD01_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601853.1"
                     /translation="MDLFQELICLVQKTFYFFLSICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNIL"
     gene            complement(20725..21736)
                     /locus_tag="VXD01_001477"
                     /pseudo
     CDS             complement(20725..21736)
                     /locus_tag="VXD01_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         6312 a         4537 c         3997 g         6937 t
ORIGIN      
        1 taaaaatttg tttgctaata tctctttctt ctgattttgt ttcaaggatt attgctacat
       61 cattcatatt tttaggtaaa taccaaccat ctggcttatc tgaatatccc ttgaagccta
      121 attgattaaa agtagttatt tgaccagtac cttgattgat gttttcttca acttcattaa
      181 agcctaatac ttctcttgca taatccctaa cttgatcttc tgtccttaaa gtcattttct
      241 attcctcgtc actaaaatta tcttcaaaac taataatatc attaggagtg caagataaag
      301 ccttacatat tctttctaaa ttcttaaatg taattggttt atcctttccc atttgtgcca
      361 taacatttgt tgtaagtcct gccatagcta ttacatctgt tttctttagt cctttttttg
      421 ctaactgtat ccataatggt ttatagttaa gtgccataat atccctcttt ttttcttcat
      481 tagatttatt taattatagc ataaatattg attttattca atcttacatt gatttagtga
      541 tttgttttag agaatttgtt gtgttattcc gtccttattt tgccataaat tgttttaagt
      601 gggacctctt atccttacca tttttacctc ctaattttga gtataaaaaa gacgacagag
      661 tttttaattt ctatcgtctg agatttacat attaaatttt catcacaaaa taagactctt
      721 taaagaatct ttaaattcat tggtatgcta attacaatat ccattattaa aatggatact
      781 ataaacagca caccaactat ttattttttg agttttaaac tttggtagaa gtcttgaact
      841 ccttatattt acataactat ttgcctctat aactattatg acacgaaacc aacaagcaag
      901 ttcaagcacc tccttatctt tattcaaatg aggactaaga tattcacaaa ctttatcata
      961 aacctcttta tcttttttca taaaaggggc atacaactta gcaaatttat cctaaaattt
     1021 tttgttgcct ttatcaatca tttcaacact cctttaaata taaaaatgat cctatcaatc
     1081 tttatattga gcctattttc taattgatac cttgcaagaa aggaataata gctgttccta
     1141 taccaagtag gaatgtaata aatgcagaaa gtcatatact gtcattcttt tctattaaat
     1201 cattttgaag tgtctcaaag catccatgat ggcttcttct ttttcaggtg tacactgtgg
     1261 aataatttgt ttatcctttt tagacttgtt gtaatgttct cgtaattcta ttccacattt
     1321 cttttttatc tgtgcaatat ataatgtcga aacttttaat tcaaatttat tccaaacata
     1381 ttctttgatt tgagcatatg ttgctttgct ctccgcactt gtcaaattca tctcatccag
     1441 ctcaatttca acacttatgt gcttatcgac atcgagtttg gacaaaagtg ctaccgtctc
     1501 gacgtgatgc gtttgaggaa atagatccac cggctggact ttcttcaatt catatcccaa
     1561 ttcttggtag agtttgatat cacgcgccat ggttgctaca ttgcaggaga tataggcgat
     1621 gcgatcggct cctgtttggg cgcttgcttt gataaagctt tctgtcaagc ccttgcgtgg
     1681 aggatcaacc aagataacgg ttggttgaat cccatcttta agccaattct tcatagcatt
     1741 ttcagctgtg tcacagacat agtgggcgtt tgaaatattg ttcagctgag catttttttt
     1801 actattctca accgcttctg gaatcagttc aacaccgtag acttctttga catgcttggc
     1861 gactgataaa ccaatagttc caataccaga ataggcatca ataatcacat catctttttt
     1921 taactctgca aagtcaatgg ctgtttgata gagtttctcc gccatttcag tattgacttg
     1981 gtaaaaggct gggccagcga tttggaagtc atttcccaac atctggtccg taatatagtc
     2041 ttgaccataa agagtgcgcc actccttacc aaaaatcgca ttggtattct ggtcgttgat
     2101 attttgcatg acagacacaa tctctgggaa ctgcttgata acttgttcaa tcaattggtc
     2161 aacacgaaaa acttttggac gagttgtcac caaaacgacc atgatttgtt ctgaatagtg
     2221 accacgacgc accacaagat tccgaatcaa tccagactgt tccttttcgt cataaggttt
     2281 taaatcaaaa cgacggagca ggtctcgaag agctactacg acttggtcaa tgacaggatc
     2341 ctggataaag aaatcttcaa ggggcatgag gttgtgcgaa ttcttacgga aaaatcctgt
     2401 ttccaagaca ccattcactc gacgaacggg cacctgcgcc ttattgcgat acttgactgg
     2461 atgttccata ccaagcgttt cagcaacttc tacatctgca attccagcaa tcttgtagag
     2521 actgttcttg acttgcttgg ttttaaactt gagctgttct ggataagaaa ggtgtcctaa
     2581 atccgcgatt cctgaacgca ggtaagccaa atctagatct tgattacggt gtggtgactg
     2641 gacaaggtat ttttcaactt ttccaaagcc aatcttttta ttgaccttga ggacacgcat
     2701 gagaattttt tcactcggta aagcattctc tacaaaaaag accaaaccat ctaccttggc
     2761 aactcctgcc ccttcatggg tcaaatcaac aatttcaact tctacaatat catttttctt
     2821 taacattctt ttctctttct attggccgac aaaaaagacg gcaacgttac ggttaccatc
     2881 cattatacca tgaaatttct taagaaccaa aactcttgaa gaagttgaca agggcttgcc
     2941 agagggagct taagaagtta ccaccgtcct ctagcgcctt atccgcatca aagttaaggt
     3001 tgatattttt aaaactgtcg ccagcttgtg atacgatgct ttgtttaagg tcatttaggg
     3061 ttttagtgaa atctgcattg ctgaggatat cactctttga gagattcaag gcaaaattga
     3121 tgatgatatt gatctggttt cctgttatga cctgatcaag tttgtaattt tttaaggtat
     3181 cttcaacaat cttgcggata tcttcttctg tcagatttcc cttgctttct ttagctttgg
     3241 cgagtcctga cttgatatca gctagggcaa cgtttaattt attagcatca tagcctgatt
     3301 tgtccttgtt ttcagcattg atatctgaca aagcttttag ctcttcttga gccaaatctt
     3361 tattggcttg cggcaccttg gctccattag cttctagcga atagtagatc ccagccaaag
     3421 cactctcacc tgtaactgga atgggtgctg ctacagtgat tttggcgtgt tccacaccca
     3481 aagttacggc tgcatttcgg tacatatcct gagttacctt agtgatgttt tcaggtgttt
     3541 caatcttgac ctcaagtggc gatttgtcac ctagcttttg aatcttggct gatgaataca
     3601 actgtaagct agagtcattg gccacattca tgattttaga ataaacatca ggtgtcatgg
     3661 tcttgagttc tttggtatct gttgaggcat tgtagcccag ttttttaaga gtttgatttt
     3721 tttggtcttc agatagggag gaacctagga catattcagg ttggacatag gtttcatcga
     3781 taactttttg aacatctgtt gctgcatgga cgctattcat agctgttact gcccacaaga
     3841 ccgcagcact agtcagaaag agtttctttc tcatagggaa tttcctcctt tacttcttta
     3901 gagtaatata tctatcttaa agaaaactta taacaaaaac acctggtcta gccagatgtt
     3961 gaaaagagag tgaaacattt gatgatgtaa aggttaagtc gtacctgtct agaataataa
     4021 tagtttcctc catttacata gagttcagca ccgtgaaaaa tggaaatggg atgaatataa
     4081 ctataagtct ttccagtcgt attaccaagc aagggggcaa cagtctcacg agagtactgt
     4141 ttggctagag ccaaggtatt ttccttgcca ttttgggcga taaaatcgat ataggcaggt
     4201 ccaaaattat aggcttgaac agctgtccag atatctacac ccttcttctg cgccagatag
     4261 agattgcctg tcagagtttg aatgccttgc cgaatgctag aggcattatc attgatggtg
     4321 ttggtggaac cacttgcaga ctcactagac tgcataacat cgccttcttt tccttttgtt
     4381 tcagtataaa tcatagcaag cacaagctct tcgtttgctg gggtgtcttg ttcactcaag
     4441 atttctcgca ccatgggttg ataggtcatg acttgtttga catcttgatg aacgcggtaa
     4501 gctttatagc cagcaaaaag gaagactgct agtacaagca ctcttcgaat tcgtttaaac
     4561 attatttact ttggatatcc tcgatatttt tgattaagat agagtaggtt ccattttcgt
     4621 tttggataaa ctcaacagac tcggcgtctt gatagacgtt attgggaacg atgagctcaa
     4681 ttccatttga taaggagagt ttttggtttt caaatttctt taattggcga ctgacatcaa
     4741 tttcatcaaa ttgaacaggt tctggtacgg cttctttgac ttggtcaata aagctcaaac
     4801 gagccgtcag attgttgtca aaaaggtcat tagccaattt ctcaggtgac aattcattgc
     4861 tttcttctag gttgttgaaa atagctgatt tgaccttgga ttgaaattga aaatcatctg
     4921 tgttaaaaga ttcagcaatt ctctgggctg ttttttccag ttccttgata gattttttag
     4981 gagaaatctt aggagcgaca gcaagaagat tatctgaaaa atagttcaaa aaagtcccgt
     5041 tgtacttgat tcgtttttca atcaggtgat acttgctact ctgaagattg accaccaagg
     5101 cctcatcagc tcctgttcca aatccaggca ggttattctg agttagcttg attggattat
     5161 caacttctcc tccgaggtgg gtcaaggtct cccgcagggc aattcgcaag aaagcgaaat
     5221 gttctacacc ttctttagaa aattgaacaa aaatcaagtc attggtcttg agattttcag
     5281 aaatgctaaa ctcctctttc cagagattag ccagcgttac tgatgtctcc aacaaatcgt
     5341 ctgtaatatg attgaagaag ggattttctt cttcgaaaat cccagtcttg gcttcatctg
     5401 aatacacatg ttcaattttt ttacgtaggt attcttcgat ttttggagta atattgagaa
     5461 acttatctgc taagaacagc tcggtatcat ccggactgaa ctggtgaata atggctttct
     5521 taatataaat gtccataaaa gttttattcc tcgtataatg ggaaggcatc tgtcaattct
     5581 ttgactgcac ttctcacttc ttctaataca gcctcatttt ctgaattctt aagggtttta
     5641 atgatgagtt cagccacttt gcgactttct tcttcaccaa atccacgtgc agtaatagct
     5701 gctgctccga tacgaatccc acttgtcttg aatggtgaca aggtttcgta agggattgaa
     5761 tttttattta gggtaatatt gacttcatcc agcaagtttt gagcaacttt tccgttttct
     5821 acaaccttag tcacatcaac aaggaagaga tggttttcag ttccacctga aataatacgg
     5881 aaatcagggt cttgcaagaa gacatctgcc atagccttgc tgttcttaat tacattggca
     5941 gcatattcct tgaaggctgg atccaaaact tctttgaagg aaactgcctt agccgccaca
     6001 acatgctcta aaggaccgcc ctgaatacct gggaaaatag ctgaattaat ttttttagca
     6061 agttcttcgt cattggtcaa aatcaaacca ccacgaggtc cacgaagggt tttgtgggtc
     6121 gttgttgttg tgatatgagc gtatggaact gggcttggat gaaggccagc cgcaaccaaa
     6181 ccagcgatat gggccatgtc caccatgagc ttcgcaccga cagcatctgc gatttcacgg
     6241 aattttgaaa aatcgataat ttgagaatat gctgaagcac cagctacaat cagttttggt
     6301 tttacttctt gggcttgttt caagatagca tcaaagtcta agagttccgt ttcaggatca
     6361 acactataag aaacaaagtt gtaggtttga ccagggaagc taacaggagc cccatgagtc
     6421 aaatgaccac ctgatgccaa atccattccc ataaccgtat cacctggctc aatcaaggat
     6481 atgtaagccg cacagttggc ctgacttcct gaatgtggtt ggacattggc aaatttagca
     6541 ccgaaaattt cttttgcgcg ttcaatagca agagtctcta caacgtctac tacatcagtt
     6601 ccaccataat aacggcgtcc tgggtaaccc tcggcatatt tatttgtcaa gatagaccct
     6661 tgagctgcca taacagcctt ggaaactacg ttttccgaag caattaactc gatattattt
     6721 tgttggcgtt cttcttcttt ggcaatagca ttccagagat cagcatcata tgctttaaaa
     6781 tcatctttgt caaaaatcat aggtcttctc ctttattgtg tgactagtcc attagtttga
     6841 ttttacaata agaaaatcaa actaaaagat gcgaataaac cgtttctgca ttttatcaca
     6901 agtatagcca actttttcat aaaatgcatg agcacccaga cgatgattgg cagaatttaa
     6961 gcggataaac ccataaccac atcttttggc ttcttgttcc aacccttgta gtaaactttt
     7021 accgatacct tgaccttgcg cttgaggtga aactgctaaa gctaagatat taaatcctgc
     7081 tttggaatag agtgattcgt aaacttcagc gtggacatat ccaagtaaga catgattagc
     7141 tgcatcctca tagccaagta ggaaatgatg ggaatcctga gacagtctag ctagttggct
     7201 agccgtttcc tctggactaa aagtataacc caaagcctct tggttgatgt cacatatcgc
     7261 tttcacatct gtttcttgca aatctcttag catttcaagc ctcctcaaaa gaaatctctg
     7321 gcaaccgagc aagaatatct tctcgtttaa ttgcgccttg gcgtaagatt ttcaccttgt
     7381 ctccagacaa atccacaata gttgaatcct gtccagttag aaaagcatcg tcttccagac
     7441 ccagaacctc ttggtcaaaa tcctttagaa tttgatcaaa ggttacacca cttgcctgac
     7501 ctgagatatt ggcagacggc ccaatcaagg gacctgtctc tcgaattaaa tccagtgtga
     7561 tagggtgact gggcatccga aatccaatag ttgcaaggtc agaatttacc caatagggaa
     7621 ctcggtcatt ggcttcgaga ataatggtca agggacctgg caaaaaggtc tctacaagtt
     7681 tttgtagata agctggctga ttcttagaaa agtgcaagat atcctctaaa gaggcaacat
     7741 tgagattgag cgccttgtct ctaggacgac gtttgagctg gtaaacatgg tcaactgctt
     7801 tttcgtctaa ggccttggca aaaagaccat aaaccgtctc tgtaggcaga atgacagctc
     7861 caccattttc caactcttgt ctaatcctgt ccatcatcaa ccacgaccat cctatcttga
     7921 ccaaattggt ccttgaatgt tcgaactttt ttttcaggaa gatgttttct aaaaagttcg
     7981 ggaacacttt gaccttgctt gtatccaatt tcaaggtaaa tcttaccacc atctttgaga
     8041 tagtcttttg catcttccgc aattctacgg taaatagcta ggccatcctc gtctgcaaag
     8101 agagctagat gaggctccga atacaagaca ttcaagccta cctctgactc atcttcacga
     8161 gagatatagg gtggattgga aacaattata tcatattttt cagaaatttc tgtaaaacag
     8221 tcagattttt taaaaaatat ttgaagattt tgatttttag cattttcgct agctaaatct
     8281 aaagcctctt gagaaacatc tgctgctgtc actgaccaat ctggtctatt ttttgctaga
     8341 gcgagagcaa tagctccact acctgttcca atatccagaa ctgaaagatt cgtctcaaga
     8401 ttttcagtta gaataagctc cactaactcc tctgtttctg gacgaggaat caaaacccgt
     8461 tcatccacct ttaaatgcat tccataaaaa tctgcctgtc caatgatgta ctgagctggc
     8521 ttgtgagctg ctagttgctg gtaaatatct tctacaaatt gtttttcttc ctctgttgtc
     8581 acctcctgct ggagggcaaa aataaagtct gtaaaagata gatttttcag actacgatag
     8641 acaaaagaga ggctttccgc ttcctctcct tgtcttatca actcttcttc aaaatttgaa
     8701 aataattgag ctaatttcat tatttgttta attcttctag tttttgtgtt tggtcataaa
     8761 gcaccaaggc atccacaact tcgtccaatt taccagacaa aatcgtatct agtttttgga
     8821 gggtcaagcc gatacggtgg tctgtgacac ggttttgtgg gaagttataa gttcggatcc
     8881 gttctgaacg gtcaccagta ccgattgtcg acttacgctc agcgtcttgt tcatcctgag
     8941 caatctgagc aaagtggtca gcgacgcgtg cacggataat cttcatagcc ttctcgcggt
     9001 tcttctgctg ggtacgttct tcctgcatct caaccttgat attggttggc aagtgaacga
     9061 tacgaacggc agtcgcaacc ttattgacgt tctgtccacc agcaccagag gcgtgataga
     9121 tgtcgacacg aaggtctttt ggatcaatgt cgtattcaac ctcttcaact tctggcataa
     9181 caagaactgt cgctgtcgaa gtatgaacac ggccttggct ttctgtcaca ggaacacgtt
     9241 gcacacggtg ggcacctgat tcatacttaa gcttagagta tacagactga cctgaaacca
     9301 tagcaaccac ttctttaaaa ccaccgacac cattcataga ggcttccatg acttcaaagc
     9361 gccaaccttg ggcttccgca tacttttggt acatagttag caaatctcca gcgaaaagtg
     9421 ccgcttcgtc tccaccagct gctccacgga tttcaaggat gatattcttg tcatcgtttg
     9481 gatcctttgg aaggagcaag atttttagtt tttcttcgta ttcttctttt tcagccttgg
     9541 catctttgag ctcttgcttg gccatttctt ccaagtccgc atctccgcct gattccttaa
     9601 tcatctcttc agcatcgacg atattttgaa ggacttgttt gtactcacgg taggctgtaa
     9661 ccgtgtcacg agttgaagcc tcttcttttg aaagctccat aaaacgcttg gtgtctgaaa
     9721 cgacatccgg gtcactgagc aattctccta attcttcata acggtcttct acagcttgta
     9781 gttgatcata aatgttcatt ttttctcctt atttctcaat tgttaaaatc gtatatcgct
     9841 actacttcgt tctcgtatat ttccccagtt tctttaaatc cataactgag gtaacaagat
     9901 cttgcatgtt cattttctgg ttcataagac aaccaaagtt tattgcctaa acctgctgac
     9961 gctgtccgaa catagtctag tactttatcc ataattggtt taaaatatcc ttgattttga
    10021 aaattcttat caatcataaa acgaaatagt aaataatttc cactacttat tccgatcttt
    10081 ttatcataag ctatcatcac aaaacctata attgcatcat tatcataaac tgccaatgga
    10141 gctacaaaat ctccattttt agtgtagaca tatgcttcag ctaaactaat tgcgttggtt
    10201 gcaatgaatt gtttttgata tttcttgaca tccaaattca aaacatcaaa ataattttcc
    10261 attgtaacat ctcttagttc aattgtcata gttttgctcc ttgttagagg ttatcattgg
    10321 cgcaaaataa tgtttacggc aaaccgagat ataggtttca ttaccgccaa tctggatctg
    10381 ttctccatcg taaacgggca gtccatcctg tgttcgcaaa accatagttg cctttttctt
    10441 acaatactga caaatggtct tgatttcatc aatcttatct gctaaaagca agagatactt
    10501 ggaaccttcg aacagttcat tgcgaaaatc atttttcaaa ccaaaagcca tgacgggtat
    10561 atctaactcg tccacaacac gagctagatc gtaaacatga tgacgtttga gaaactgggc
    10621 ttcatcgacc aacacacagt aaggtgtttc tggtaaatca cggataaatc caaagatatc
    10681 cgtcgtctcc tcaatcgcaa gagcagggcg tttcataccg attcgactcg acacatagcc
    10741 aacaccgtca cgcgtatcca gagccgaggt cataatcaca acaccttttc cttgctcctc
    10801 atagttatag gccaccttga gaatctcaat cgtcttacct gagttcatgg tcccataacg
    10861 ataatacaac tgtgccatgt ttcttgcttc acgtccgttt ctaaattttt gctacattct
    10921 agtatatcat aattttctga agctttaaac ggcaaaatgt ggtaaaatag aagaaatcaa
    10981 aaactagtgg aggaagctat tatgccattt gtacgcatcg atttatttga aggacgcacg
    11041 ctcgagcaaa agaaggctct tgctaaggaa gtaacggaag ctgttgtccg taacactgga
    11101 gcccctcaat ctgctgtcca tgtcatcatc aacgacatgc cagaaggaac ttacttccct
    11161 caaggtgaaa tgcgcaccaa ataagctagc ttaagcagaa ttgcttaggc tttttcaatc
    11221 tccaagtagc attcattgaa gaaatagttc aaatttgtta caatttgaaa agagacttgg
    11281 agaattttcc aagaaaagag ctattgatta aaggaaatat tatgattaca cgtgaatttg
    11341 ataccatcgt tgctatctct actccactag gtgaaggggc tattggtatt gtccgcctga
    11401 gcggaacaga cagttttgct attgcgcaaa agatttttaa aggaaaagac ttgaacaagg
    11461 ttgctagcca cactctcaac tacggtcaca tcgttgatcc tctgactggt aaagtcatgg
    11521 acgaggtcat ggtgggagcc atgaaatctc caaaaacctt cactcgtgag gatattatcg
    11581 agattaacac ccacggtggg attgcggtga ccaatgagat tctccagcta gctatccgtg
    11641 aaggagctcg gttggctgaa cctggtgaat ttaccaaacg tgccttttta aacggtcgcg
    11701 tagatttgac acaggctgag gcggtcatgg atatcatccg cgctaagaca gacaaggcca
    11761 tgaacattgc ggtcaaacaa cttgatggtt ccctttctga tcttatcaat aatacccgtc
    11821 aagaaatcct taacacactt gcccaagttg aagtcaatat cgactatcct gaatacgatg
    11881 atgttgagga agctactact gccgttgtcc gcgagaagac tatggagttt gagcaattgc
    11941 taactaatct ccttaggaca gcccgtcgag gtaaaattct tcgggaagga atttcaacag
    12001 ctatcatcgg ccgccccaac gttggaaaat ctagcctgct caacaacctc ttgcgtgaag
    12061 acaaggccat cgtcacagac attgctggga caacacgtga tgtcatcgaa gaatacgtca
    12121 acatcaacgg tgtccctctc aaattgattg acacagcagg tattcgtgaa acggatgaca
    12181 tcgttgaaca aatcggtgtg gaacgttcga aaaaagccct caaggaagct gacttggttc
    12241 ttctagtact aaatgccagc gagccactga cagcccaaga ccgacaactt cttgagatta
    12301 gccaagatac aaaccgcatt atacttctaa ataaaaccga cctgccagaa gcgattgaga
    12361 cttcggaact acctgaagac gttattcgta tttcagtcct taaaaaccaa aacatcgata
    12421 agattgaaga gcgaatcaac aacctcttct ttgaaaatgc tggtttggtt gagcaagacg
    12481 caacctacct gtccaatgcc cgtcatattt ccttgattga aaaggcagtt gaaagcttac
    12541 aagctgttaa tgagggtcta gaactgggga tgccagttga tttgcttcaa gtagatttga
    12601 cacgtacttg ggaaatcctc ggagaaatca ctggggatgc cgctccagat gaacttatca
    12661 cccaactctt tagccaattc tgtttaggaa aataagaaaa atccatgatc cttcattcgg
    12721 tcatggattt tattgtcttt attagtaatc tggtcttaag acacctgtta cagttgcctt
    12781 ggtcgcttcg tagtcgccat ctacgacaac cttgataatg cgtttagcat cttcttctgg
    12841 tgctggaaca agaggtagac gagttggtcc agcttcaaat cccatgtagt tcaaaactgc
    12901 cttaactgga gcaggacttg gataagagaa gagagcatta accttaggaa tgaatttacg
    12961 ttgaatagct gcggctttct tcatatcact ttctgcaatg gcaataaaca tctcgtgcat
    13021 ttcatcccca tttgtatgag aggcaacaga aataacccca tccgccccaa ggttcatggc
    13081 atggaaagca tctccatcct caccagtata gaccaagaac tcttctggtt tgtgctcaat
    13141 caagtaagcc atattagcca agctagtaca ttctttgaca ccgataatat ttggatgatc
    13201 agccaagcga agcatggttt ctggagttaa ttcaacaacc acacgccctg gaatgttata
    13261 gataataatt ggtaggtcag aagcatctgc aatagcctta aagtgctgat acatcccttc
    13321 ttgagaaggt ttgttgtagt aaggaacaat agcaagccca gctgcgaaac caccaaattc
    13381 cgctacttct ttgacaaact caatagagtc acgcgtatca ttagtaccta cacccgcaat
    13441 caaaggaacg cgtccattga caaccttttg tacagccgca aacaactcca actcctcatc
    13501 gtgggtcaaa gttggactct cagcagtcgt tcctgcgaga agaattccat ccgtatgatg
    13561 ggccaataaa tgctcaatca aggctggaat agcatcaaag ttaatggaac catcctcatg
    13621 gaagggggta ataaaagctg taatgatttt acattttttt aaatcttgat aagacacgaa
    13681 aacacctctc tatttcaaag aaggagttca tctgaactcc taaacgatat gactatttta
    13741 attcaaattt caattcagct gttggacgaa ccaatccacg ttcatgaaga gtttcagcaa
    13801 tctgaactga gttccaagca gcacctttga gaaggttatc tgaaacaacc cacatgtgaa
    13861 ttcctttttc tgcatccaag tctttacgga tacgaccaac aaaggtatca cgtgaaccaa
    13921 ctgcattgat ggcttgagga tagatttgat gaactacatc atcttcaaga acagcacctg
    13981 ggaaggatgc gatagctgct ttgacttctt caattggagc cacttccttt gtttcaatat
    14041 aaactgactc agagtgagct gacaagactg gaatacgcac acatgtcgca gatactgcaa
    14101 tgctatcatc ttccataatt ttcttagttt ccttggtcat cttcatctct tcgtacgtgt
    14161 aatcattatc agtgaagaca tcaatttgtg gaagagcgtt aaaggcgata ggataatgtt
    14221 tcttgtcacc acctgaaggc aagatttccg catgcaaatc acgtggtttc actccatcat
    14281 tcaagacctc acgaagttca cgttgtgtct caagaattgc tcccatacca gcacctgaaa
    14341 cggcttgata agttgaaaca atgatacggt ccaagcccca tttttggcga accggctcaa
    14401 gagccaccat catttggatt gttgaacagt tagggcaggc aatgattccg ttgtgggcat
    14461 caagtgcatg agcattgacc tctggaacaa ccaaaggaac atctggattt tgacggaaat
    14521 aagatgtatt atccactact accacgccag cttttactgc gtatggtgca tacttagctg
    14581 atgtcgaacc acctgctgaa aagagagcaa tatcaactcc ttcaaaagct gtttcagtcg
    14641 tttcttcaat cgtaatatct tgatctttaa atttcaatga cttacctgct gaacgtgcag
    14701 aagcaaggta acggatttta tcgattggaa gtgttgattc ttccaacatt tttatcatct
    14761 gagcaccgac agcacctgtc gcgccgacta cagcaactgt atatcccata aataacctct
    14821 ttcggaattt tctaaaaatt tctataatag aagtattata ctactttttc catgaattgc
    14881 aaagcttttt catcattttt tggaaaataa aaatccccaa tcgctagact agggattaag
    14941 aggcatcttc atgtgatgag caggttcaca caactcatca aggtccgctc ctgcgttatg
    15001 acctccttat gctcaatagt agcccgaaga ctacctatcg actcatcgca tctactattc
    15061 tactaaagag aatgactttt gtcaacagac gaaactcttt atactcttcg aaaatctctt
    15121 caaacttcgt cagcgtcgcc ttgccgtatg tatggttact gacttcgtca gtttcatcta
    15181 caacctcaaa aacatgtttt gagctgactt cgtcagttct atctacaacc tcaaagcagt
    15241 gctttgagca acctgcggct agtttcctag tttactcttt gattttcatt gagtattagt
    15301 tttatttaca caggtgcata agaaatatat tggaaaaatt gggggcagac ataacaaaaa
    15361 cccttgtaaa tcaagggctt ttctgtctat ttaatgctaa ttgccgggat tgaaccggcg
    15421 acctcatcct taccatggat gcgctctgcc aactgagcta aatcagctta cttaagaagt
    15481 atactatatt caaaaaaact tgtcaagttt ccttagaaat tttccatagg aaaaagccag
    15541 gtaagaacta cctagcttat cttcttctat ttacttaaat caattcgacg accaatttta
    15601 ccaataataa tcgctccaat aatcaatgaa gcaaattcac cgattcctgt tgtaaaccaa
    15661 gtaaggaaga atggtaattc tgctacaata tttaactctg cagcgatagt aaacatggaa
    15721 attgaaaaga ggattgaaaa gaagaaatga tcttttcgaa tcaatccgtt aaagaggtaa
    15781 tccttgctat attttgcaaa aagccaaaca cctaaactga ggaatactaa ggttgaacca
    15841 ccaccaacaa agacatctag cagtccgaag ctaaagaaat tagcaatcat acaaccgatg
    15901 gtaactccga tgatgtactt aggattgtaa aaagccataa agttcatcat ttctgaaata
    15961 cgaaactgat aagcaccata gctgatggca tttaggggcg gtgtgacagt caaaacgacg
    16021 tagatagcag cgacgattgc aatatctgca acatcacgaa tagttaattt tttcatcttt
    16081 tctcctttgg cggttatccg cgtgtaatat gcttggtgaa agaagctaag caccaagggt
    16141 tgattcattc aaccttacta gtatagcaca atagcctgct ttatgctata cttaaagcat
    16201 gaaaaaacct attcaaaaat tttttaacaa tgaaatctta gcctatctct tttttggcct
    16261 tgcgacaact ctagtttcga ttctctcacg actagtcatt tatcaactaa gtcatcagga
    16321 actccttgct acggccttgg caaatattat cggtatctta tttgccttta tcacaaatga
    16381 tacgattgta tttaagcaaa aaaagaaaaa tagacttatc cgtttagtga aattttctct
    16441 tgctcgcctt tctacttttc tgttagactt gtttttaact tttctctttg taacccaatt
    16501 tcctcacatc atagggcaat tcgtaactga aaacattgat aagataaatg ctattgaaac
    16561 aataattgca caaatattca ttattatcat caattatatc ttgagcaagg tctatatttt
    16621 tagaaaataa tgctccattt atgagccttt taattgcctt ctataatgat ttaggataca
    16681 atgaaacacg aaacattgaa aggaaaacag tatgttaaaa aatctaaaat cgttcttgct
    16741 tcgaggaaat gttattgacc ttgctgtcgg tgttgtcatt gcctctgctt ttggtgctat
    16801 cgttacttca cttgtaaacg acattatcac tcctcttatt ttaaatcccg ctttgaaagc
    16861 tgctaaagtc gaacgtatcg ctcaactttc ttggcatgga gtcggctatg gtaacttttt
    16921 aagtgctatt atcaatttta tctttgtggg taccgccctc ttctttatta tcaagggcat
    16981 tgaaaaagca cagaaactga ctggcataaa gaaagaaaaa actgccgaaa aaaaaccaac
    17041 cgaattggaa gtccttcaag aaataaaagc tctccttgag aaaaaataat cgattaaaag
    17101 gatctagcgc aaagctaaat ccttttttct ttactctttg ggtaacttgc ctgctttttc
    17161 aagcattttt ttgataagat aaggcatctt aacattctcc cgcccttttt tctcaatcag
    17221 ttttttcaca aattctggca tttgtaaatc ttcagattca gctaaaatgt ttttcgtctc
    17281 gtctgaagga actaactcat caaaggtctc ttcttctggg agaaattcct taaactcttg
    17341 attttcattg actctaattg tattgaccaa agcatcaatc aaacgagaat ctgtatttgg
    17401 cattggtgga cgatggtagt ttaccccaaa ttcctgacat aagtcataac attccacatc
    17461 attgtcaaac aagacctcaa tatgctcact gatgaaacta ataggtacaa aaatataatg
    17521 gtctggatgt tctgtctgtt ctctgagata ctccaaaaca tctggtttaa tccatggaat
    17581 accaatatca ctctcactct gccaagtgtt ggtatattgt tctgaactca agcccagttt
    17641 ttcagcgact agcttgctat tttcgaaaat ttggtctata taaggatcac caaagtccaa
    17701 ggcaaaaata ggcacactat gggctgaaaa gatgacttta aagctgtctt gctttacttc
    17761 ttcttttaaa atcttagcaa tttcatctgc ccaatagttt aagagcgctt cttcctgata
    17821 ccagtcctta ataaccaaaa attgaatttg tttgctttct aaaaattttt catagcccat
    17881 gacagagtag aaagaataat ggggctccaa aatcaagcaa atacactgtt caattccgtc
    17941 tgcttccatt tgaccgatca catctggaat aaagggactg gaaaacttat tagcaaagta
    18001 gacactgtat tcattcccca gcctagcttc taccaaggca acctcttgac gggtaatttt
    18061 ttgcagaggc gtgcctccaa ttcgtacata attatcatag agagtctgaa tctcgtggtc
    18121 ttggggtctc accccacgac gaatatttgt gaaaaaatca gctacacctt caaaggtaat
    18181 ctcttctggt gaaccgaagg tcatcattaa aattgctttt ttcatgactg cttccttgtg
    18241 atgtttttat caagtttatt ttatcattaa ttcatcgata agtaaacgct aacataggga
    18301 cattctcaat cttctgtctt ttgtttttct cttctttcta tgatacaatg gaaaaaataa
    18361 attcaaaagg agttttttta tgacttatcc aaatctcttg gaccgcttct taacctacgt
    18421 taaggtcaac acgcgctctg atgaacactc tactactact ccaagtacac agagtcaggt
    18481 tgacttcgca acaaatgtcc taattcctga aatgaaacgt gttggactgc aaaatgttta
    18541 ctatctaccg aatggttttg ctattggaac cttgccagcc aacgatccgt ctttaacacg
    18601 taagattggt tttatatcgc acatggatac tgctgatttt aatgctgaag gagtcaatcc
    18661 acaggtaatt gaaaactacg atggtggtgt gattgaacta gggaattctg gtttcaaact
    18721 cgatccagct gacttcaaga gtcttgaaaa atatccagga caaacgctca tcacaacaga
    18781 tggaacaagc ttgctaggtg ctgatgacaa gtcaggaatt gctgaaatta tgacagccat
    18841 tgaatatcta actgctcatc ctgaaattaa gcactgtgag attcgtgttg gttttggtcc
    18901 agatgaagaa atcggtgttg gtgccaataa atttgatgca gaagattttg atgtggattt
    18961 tgcctacact gttgatggtg gtccactagg tgaacttcag tacgagactt tctcagccgc
    19021 tggtgctgaa ttgcatttcc aaggccgtaa tgtccaccct ggtactgcca aagggcagat
    19081 ggtcaatgcc cttcagctag caattgattt tcataatcaa cttccagaaa atgaccgacc
    19141 tgagttaact gaaggttacc aaggttttta ccatctaata gatgtgacag gtagtgttga
    19201 ggaggcgcgt gcaagctaca tcattcgtga ttttgaaaaa gatgcctttg aagcgcgtaa
    19261 agcatccatg caatctatcg ctgataagat gaatgaagaa cttgggagca accgtgtcac
    19321 tctcaacttg acagaccagt actacaatat gaaagaagtc attgaaaaag atatgactcc
    19381 aattaccatt gctaaagccg ttatggaaga tctaggtatc acgcctatta tcgaaccaat
    19441 ccggggtgga acagacggct ctaagatttc ctttatggga atcccaactc cgaatatctt
    19501 tgcaggtggc gaaaatatgc acggacgttt tgaatacgtt agccttcaga ctatggaacg
    19561 tgcagttgat accatcattg gcatcgtagc ttataaaggc taaaaagacg aggtagctca
    19621 gctacttcgc ctttcttttt attctactgg tttttcttga tttccagtag ttgtagaaga
    19681 ttctgttgtt tcattttctg aagttgattc agcaggttta gaatctcttg tattgcttgg
    19741 tttgttttcg tcgctagcag tttcaatgtt agattctgca gttgcgtttg gttggttctc
    19801 agcactggtg ttatcactat ttgcttcagc atttcttgct ggacttgttt cttcacttgc
    19861 gctagctttt gactggattt gatgattcaa aactagaata gcttttgtcg attcaagtaa
    19921 agctgttttg tctttactct tagcagaaag ttgatctaat aatgcatcca ccttatcaaa
    19981 gtccgcatca gatccattat tactttctaa ataagagtga agcgacatga gaatatcgta
    20041 gagtttttga tagagtacaa gtgtctgaga atcttgctca gcattttcct tttcttgttg
    20101 aagggcgcta gcgatacgag tcaagacatc ttttacctga ctgtttactt catccaagtc
    20161 tgcatcagcc ttgtttgtgg cagcttttag attttctact tcttctgcca aggattgtct
    20221 gattccttct tcatggattt gttccaagag ttgatttgcc ttgttcaaaa gactttctac
    20281 ttcttccttt ctatctgtcg cagattattg gttgctatct accatgtact cctaaaacag
    20341 gagagttata atccaagatt acaaggcctt acagaaataa gaaatccaga taagacaatg
    20401 ttcgtccaag acgctattcg cttcgcacag cagcacggat tcaatatact ttaattttaa
    20461 agtttaggtg tcaagacctc tttttagtgt gcccaaaatt tagagaagta atcaatcaac
    20521 taacttttat ttttttcaaa ctttcagtaa actgacctaa agctaactca atctgtcttt
    20581 gtagatgctt ctgctatcag ctagaagttg atctactttt gccaagactg ccttctcatc
    20641 aaaagttcca ggttgatagt tggattgcag ggatggaatc ttgtttttca aagccgcttc
    20701 atatccctta gtttgaacct tgatgtagtg attgtggtcg ccatgaggaa tcacaaaacc
    20761 ttctgaatct tcacttataa ttcgattggc atcaaaacca tgaccatctt cttcctcatg
    20821 gtggacatgt ggtgacggat tacttaatac agaactagaa gaacttccta cctcttccgt
    20881 gttagagtgt gatgggggat tgttaagaga tgacttagga atatagtgat agtgatcccc
    20941 atgtcttact atataagcat cacctgtatc tctgacaata tcattagggt taaagacata
    21001 tgtggctgct aattcacctg ccgacaagtc actctcagga atgaaatgat agtgaccacc
    21061 atgtggtact atagtagatt gaaatagaat atgagcaaat tgataagggg attttaaagt
    21121 aatttctaac aatgatttag aaactatgat gtgctattct aaattcaact cactatatat
    21181 aaccatcatc ggtagtataa cgtccctgta attttgctac agatacttct gcactagctc
    21241 ctttatcgtc tttaccatgt tcttgttttt ggcgattgat ttcatctttt gttcgtacat
    21301 tttctgcatg agcttgatct ttaaggtaaa cataatactt tccatctacc ttaataatat
    21361 atcctccctt aacctaactg acgatatctt gatctttcgg ctgatagttg ggggctttca
    21421 ttaatagctc ttcactaaag agcgcatcaa aaggaacttt accattatag tagtgataat
    21481 gatcgccatg agaagttaca taaccttgat ctgtaatctt aataacaatt tgttttgctt
    21541 gaattccttc tttttgacta acctagtctg gagtcaaatt ttcagtcttc ttagtgtctt
    21601 tattactgtt tacatatgaa acacgatttt tatctgtatt ggcctgttag ctatgttggt
    21661 tcagagcata aacacacaga cttaaggaaa ggataacaac agatccagct gctatatatt
    21721 tctttttaaa tttcataatt acctcatttc tataattatt tatatgatgt cttcattatt
    21781 aaa
//
LOCUS       DAVLDI010000038        21658 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLDI010000038 DAVLDI010000000
VERSION     DAVLDI010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.038"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(1..238)
                     /locus_tag="VXD01_001478"
                     /pseudo
     CDS             complement(1..238)
                     /locus_tag="VXD01_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            409..690
                     /locus_tag="VXD01_001479"
     CDS             409..690
                     /locus_tag="VXD01_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV0601854.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYMSFIAMV"
     gene            822..1766
                     /gene="manA"
                     /locus_tag="VXD01_001480"
     CDS             822..1766
                     /gene="manA"
                     /locus_tag="VXD01_001480"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV0601855.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEDELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGTGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADNLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(1806..2723)
                     /locus_tag="VXD01_001481"
                     /pseudo
     CDS             complement(1806..2723)
                     /locus_tag="VXD01_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520377.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            2762..3566
                     /locus_tag="VXD01_001482"
                     /pseudo
     CDS             2762..3566
                     /locus_tag="VXD01_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(3563..3808)
                     /locus_tag="VXD01_001483"
     CDS             complement(3563..3808)
                     /locus_tag="VXD01_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV0601856.1"
                     /translation="MEQSPKKKKGTTLEHIILLRGVTPNGKNAIPKMSYLVDILTEAD
                     FQQVRTYIQSGNIILESNLALEEIREQVHTLLDFLQN"
     gene            complement(3823..4995)
                     /locus_tag="VXD01_001484"
     CDS             complement(3823..4995)
                     /locus_tag="VXD01_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0601857.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSNPI"
     gene            complement(5054..5899)
                     /locus_tag="VXD01_001485"
     CDS             complement(5054..5899)
                     /locus_tag="VXD01_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0601858.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6024..6581
                     /locus_tag="VXD01_001486"
     CDS             6024..6581
                     /locus_tag="VXD01_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV0601859.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            6600..7067
                     /locus_tag="VXD01_001487"
     CDS             6600..7067
                     /locus_tag="VXD01_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV0601860.1"
                     /translation="MTEKRLTWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7156..7785
                     /gene="upp"
                     /locus_tag="VXD01_001488"
     CDS             7156..7785
                     /gene="upp"
                     /locus_tag="VXD01_001488"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV0601861.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            7959..8549
                     /gene="clpP"
                     /locus_tag="VXD01_001489"
     CDS             7959..8549
                     /gene="clpP"
                     /locus_tag="VXD01_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV0601862.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            8628..8876
                     /locus_tag="VXD01_001490"
     CDS             8628..8876
                     /locus_tag="VXD01_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV0601863.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            8978..10138
                     /locus_tag="VXD01_001491"
     CDS             8978..10138
                     /locus_tag="VXD01_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0601864.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10406..11275
                     /locus_tag="VXD01_001492"
     CDS             10406..11275
                     /locus_tag="VXD01_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0601865.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11279..12235
                     /locus_tag="VXD01_001493"
     CDS             11279..12235
                     /locus_tag="VXD01_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV0601866.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12235..12999
                     /locus_tag="VXD01_001494"
     CDS             12235..12999
                     /locus_tag="VXD01_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601867.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKDKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            12999..13709
                     /locus_tag="VXD01_001495"
     CDS             12999..13709
                     /locus_tag="VXD01_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601868.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14016..14672
                     /locus_tag="VXD01_001496"
     CDS             14016..14672
                     /locus_tag="VXD01_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV0601869.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            14780..15875
                     /gene="prfB"
                     /locus_tag="VXD01_001497"
     CDS             join(14780..14851,14853..15875)
                     /gene="prfB"
                     /locus_tag="VXD01_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV0601870.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            15893..16585
                     /gene="ftsE"
                     /locus_tag="VXD01_001498"
     CDS             15893..16585
                     /gene="ftsE"
                     /locus_tag="VXD01_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV0601871.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            16578..17504
                     /locus_tag="VXD01_001499"
     CDS             16578..17504
                     /locus_tag="VXD01_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0601872.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLRI"
     gene            17790..19970
                     /locus_tag="VXD01_001500"
     CDS             17790..19970
                     /locus_tag="VXD01_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0601873.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAIMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20022..20837
                     /locus_tag="VXD01_001501"
     CDS             20022..20837
                     /locus_tag="VXD01_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0601874.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAVLNWK"
     gene            21043..>21658
                     /locus_tag="VXD01_001502"
     CDS             21043..>21658
                     /locus_tag="VXD01_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000465984.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0601875.1"
                     /translation="MFFQDRKIKYSIRKLSVATVSLAIGFLFAPAALGVAQVAQADEL
                     STTEQVENKAENQVSVVSFATEQEESETTYVDTTNKVTWTFAGYDKEKIVVGKGRQTF
                     LGSWVPTPNPEYVFKSSKAGVPLPQSILGMLPKDEASYKVGDTIVAKQPAVESVVEEE
                     KDYVWTFKGYDQKNATYNGKRVTFTGIWEVTPRPHHVSYTFVSVT"
BASE COUNT         6627 a         3968 c         4721 g         6342 t
ORIGIN      
        1 ctgctttcaa aaagcattct agtccatctc cgattaacga tggactttat cacctccttc
       61 tccagtcctt gtatgacatc ttggagttga ttcatgacat cttccaaagt tcgaaaggct
      121 ttattcttaa atccacgttt atgaatctct ttccacactt gttcgatggg ttcatctctg
      181 gtgtgtatgg aggaataaag gtaaaaccaa tattagtcgg aatctttata agatttgccc
      241 atcagacgaa atagaatgat ttgaaggcat ttatgatatt tagctgtacg agagtcttta
      301 aaaagtgttt tgatggtttg gatttcttct ttagttgatt tcatatcact attatataat
      361 gctttttgat tttagtatag tattatcgta gaaaatggac tcggtgctat ggatacaccg
      421 gatgagaatg gttatgtagc agatgactat cggattactt acttagaggc ccacatcaag
      481 gccatgcgag atgccattta caaagacggg gttgacttgc ttggttatac gacatggggc
      541 tgtatcgatc cggtttcagc tggcacaggg gaaatgaata agcgctatgg ctttatctat
      601 gtagatcgag ataatgtagg aaacggagct ctcaaacgta gcaagaagaa gtccttctat
      661 tggtacatgt catttatagc aatggtgtaa gcatcgagta gagcacattt gtttactatt
      721 tttataaaat cttctccctg ctttataaga tgtaaaaaag agttcaaatg gaactctttt
      781 tttgctataa tgaggggaga aaaatcagac aggagattaa gatgtcagaa ccattatttt
      841 tacaatcagt tatgcaagaa aaaatctggg gtggtaccaa gctacgtgat gagtttggct
      901 acgacatccc aagtgaaaaa gtcggagagt actgggctat ctcagctcat ctaaatggtg
      961 tttctaaagt tgccaatggt cgttacgagg gaacagatct tgctactttg tatgcggaac
     1021 accgtgaatt atttggcaat cgtccagaac ctgtatttcc acttttgacc aagatcctcg
     1081 atgccaacga ctggctcagt gtccaagttc acccagacga tgcttatgga ctcgagcatg
     1141 aagacgaact tggaaaaaca gaatgttggt acatcattgc agcagatgaa ggttcagaga
     1201 ttatctacgg tcacaatgcc aagtcaaaag aagaactccg ccagcaaatc gaggacaaga
     1261 actgggatga cttgttgacc aaagtccctg ttaaggctgg agatttcttc tatgtaccaa
     1321 gtggcaccat gcatgctatc ggtactggca tcttgattct tgaaacccaa cagtctagtg
     1381 atacaactta ccgcgtctat gactttgacc gaaaggacga taagggcaac ttgcgtgaac
     1441 ttcaccttga aaaatccatc gatgttttga acattggcga gccagcaaat agccgtcctg
     1501 taactgttaa agcagataat ttgcgttcca ctttacttgt ttctaatgat ttcttcgcag
     1561 tttacaagtg ggaaatcact ggaaaagttg attttgagaa gacagctgac tacagcttgt
     1621 tgagtgtctt ggctggtcaa ggtcaactaa ctgttgacgg gaaaaactat ccaatccaaa
     1681 aagggagaca ctttatccta ccaagtgatg ttgaatcttg gactctagaa gggcaagatt
     1741 tagaattaat tgttagtcat ccataaaaaa gaaaggacct gagttcatta ctcaagtcct
     1801 tttgattaca taaattgggc gatgaagacc acgatgatga ttggaatgac gaaacgaaga
     1861 aggaagagcc agacttggaa cagtccttgt ttccatgctc tttcatcgag atggagttcc
     1921 tccattgcaa gagccttttt aaagatatag cctgtaaaaa gtgaaaggaa gagagctcca
     1981 aatggcatga ggagattgga aaccaagaag tccatagcgt caaagaaggc tttaccaaaa
     2041 atgtgaacat ccgccatgac accgtaagat agggctgaag gaatgccaaa gacaaaggtc
     2101 aaaattccta aaataacact ccatttagca cgcttgctgt tgtcctgatt ggtgatattg
     2161 tctacattga tttccagcat aacgacagaa gaagtgacag tcgcaaagag gaagaggaca
     2221 tagaaaatgg ttccaaaagg catcttgtca aagagttgag gcaagacgat aaagaccaag
     2281 ctcggtcccc cttcagactg gatattgaag ggggaccgag cttggaaaat ggctagacct
     2341 gccatgatgg ataccgagat attcatggct acgatggaga ttcttgactg gaccagattg
     2401 gttttcttgt ccaagtaaga agcataggtc aacatggctg taacccctag tgagagggca
     2461 aagaaagatt gtctcagagc atagaggaga ccagcgctag tcagttttga aaaatctggt
     2521 ttgaggaagt aaagaacccc ttccatggca tttggcaaac tgagagagcg ttcgatgatg
     2581 acgacaaaga tgataaagag caggggcatc atgactttcg aagctctttc aatccctttt
     2641 tgaaccccac gtgatacaat gaagatattc aataggataa aggtcgcttg agctcctaga
     2701 gcaatggctg gatttgaaat gatcagactt cctgcgaaac aaaatatggc atagtagttc
     2761 tatgaatgat gaagcaagta aacaactaac tgatgcacga tttaagcgtc ttgttggtgt
     2821 tcagcgcacg acttttaaag agatgttagc tgtattaaaa acagcttatc aacttaaaca
     2881 cgcaaaaggt ggacgaaaac ctaaattaag cctagaagac cttcttatgg ccactcttca
     2941 atatgtgcga gaatatcgaa cttatgaaga aattgcggct gattttggta tccacgaaag
     3001 caacttactc cgtcggagcc aatgggttga agtaactctt gttcaaaggt ggtgttacga
     3061 tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg gaagtaaaaa
     3121 tcaatcgacc taaaaaaaga attagcgaat tattctggta aaaagaaatg ccacgctatg
     3181 aaggctcaag cgattgtcac aagtcaaggg agattgtttc tttggatatc actgtgaact
     3241 attgtcatga tatgaagttg ttcaaaatga gtcgcagaaa tatcggacaa gctggtaaaa
     3301 tcttggctga cagtggttat caagggccca tgaagatata tcctcaagca caaactccac
     3361 gtaaatccag caaactcaag ccgctaacag ttgaagataa agcctataac catgcgctat
     3421 ccaaggagag aagcaaggtt gagaacatct ttgccaaagt aaaaacgttt aaaatgtttt
     3481 caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg gttgctggca
     3541 ttatcaatca tgaactagga ttttagtttt gcaggaagtc taatagagta tgaacctgtt
     3601 ctcgtatttc ttcgagagct aagttacttt caagaataat atttccactt tgaatataag
     3661 ttcgaacttg ttgaaaatca gcttctgtca agatatctac tagataagac attttaggga
     3721 tagcattttt tccattagga gtgactcccc ttagcaagat aatatgttcc aaagtagttc
     3781 ctttcttttt tttgggggat tgttccattt agtaatgtat atttagattg gatttgatcc
     3841 cgccacccag ccggtacaga gagcagaagt gatgttaaag ccacccgtgt gggcattgat
     3901 atccataact tcgcctgcaa agtggaggcc aggtaccagc ttactttcaa gggttttagg
     3961 attgatttcc ttgagactga ctccaccctt ggtaacaaag gactttgcaa gggacatttt
     4021 tccagttaca ggaattttaa gttctttaat ggactggaca agttgttctc gttccttttc
     4081 agtcagctgt ttgacttttt caggatatcc ttgtacaaaa aattcggcca agcgttctgg
     4141 taacaaggtt tttaaagcgt ttttcaagga tttttcccga ttttcttcta gaaatgtaac
     4201 caagtccttc tcagaaagtt gaggcaaaac atcgagtgag agaacctccc cacctttgac
     4261 aaagctagac atgcgtaggg cagcaggacc tgacaaacca aagtgggtaa agagtaaatc
     4321 atgagtgatg acatgcttac cataacttag ggtcacatcg tccaaagaaa tcccttgtaa
     4381 ggctttatgt ggaaaatctg ttaataaagg actttcagca gcctcaagct cggtgatggt
     4441 atgcttaaaa tggcgagcaa tctcgtgacc aaaaccagtc gaaccagtcg aaggataaga
     4501 cttaccacct gttgtgacaa tgagtttctc acaagtgaag gtttgatccg ctgacttaag
     4561 gacaaactgg tcatctactt ttttaacaga aacgatttct atttgagtag caacttgacc
     4621 acctagttca gtgattttct tttccaaagc ttcgataata gtccgagact tgtcactggc
     4681 tggaaagacg cgtccgtggt cttcgacctt aagtttaaca ccattttctg taaaaaagtt
     4741 gatgatgtca tgattatcga actgggagaa aacactgtaa agaaagcgtc cgtttccagg
     4801 aattccagct agcaggttgt ctaagctacc attgttggtc acattgcaac gtcccccacc
     4861 agtcccagct aatttttttc caagtttccg atttttttcg atgaggaggg ttttctgtcc
     4921 ataaaagcta ctggaaatcg tagccatcat accagcaggt cccccaccga tgacaatagt
     4981 atcaaaatgt ttcatagctc tattgtacca caaaaaaaca agagatgatg gtcacctctt
     5041 gtcaagaatg caattaatca atttcatagc ccatcagcaa accgccctct tctgcataga
     5101 aactgcagag accagaggtt ggtagaattt taatatccgc ttgtgggaag gtttcacgga
     5161 ttcgctctga gagctgttga caacattttt cgttattgcg ttgggccatg acaatacggc
     5221 caccagcata tccagctttt actaactcat cataggcagc ttgaactgat ttctttgatc
     5281 cccttgcttt ttgtagcaat tcgagagttc cagtttcact agcttttccg accatacgaa
     5341 tgttgagaag gccaacgacc gtaccgataa gcttgctcaa acggccgttc ttcaccaagt
     5401 tatcgacttt ggctaggaca aagagcaact tagttttttc ttgataggcg gtgatagctt
     5461 caaccacttc ttcaaaagac aagccctggt caatcaagtc attcaatttt tctacgagta
     5521 ggtcaacttc accaccagca gataaactat caatcacatg aatcttagtg tcaggatggt
     5581 cttccagata aatattcttt gctagttgag cactattgtg actgccagaa agggtacctg
     5641 tgatggttac taggaaaatg tttttggcac cttcaaatgc tcgcaaatag tcatctgggc
     5701 ttggacaagc cgattttgaa gcttctgcag ttgcatacat ggtttccatc atttggtcaa
     5761 tatcgagact ggcgtcatca acaaagacct gatcagctac ttgaatggtt aaggggacac
     5821 ttacaaaggt tgtgttaata gctggtgttg gcagttgacg ataatcacaa ccagagtcag
     5881 caataatctt ccaagtcata gaaattctcc atctttgtca gttatacatt gacaaaggtt
     5941 ctgtcttttt ttacaattat atcatgaaaa cccttgaaac aaaagcatca tccgtctgtt
     6001 gtgacaagta gaaagaaaat gttatgtctg aacgtagaat ctctgaaaag tctcttgaaa
     6061 atctcagaaa atcaaaccaa gaatccaatt tattaaccag agaagccatt gaaacagccc
     6121 tcttgcaact cttggaaaaa aaggaactga ccaagattag tatttctgaa ttggtcaaac
     6181 gtgcaggtgt ttcgcgtgcg gccttttatc gcaattatga ctccaaagag gaaattttag
     6241 agagcgtctt taaacgaact gtccacaata ttatggaaca gctgcatcat tacgatttaa
     6301 agacagacct ttatttggtt tgggttcacc ttttccggga ggccagaaag gaagctagag
     6361 tgattcaatt ggccttggat taccatctgg aaaaaatctt tgtccaagcc atgcaggaat
     6421 ttctagaaaa ataccatggg aaatcaaaag gtgtcagctc ttatcttcat tccttctgga
     6481 gctcagccat cgtctctgtc cttctaaaat ggatcaagga tggcatgaag gtaccagctg
     6541 aaaagattgc agatttaggt ttaccatttt ttaaaaaata gagaaaaagg agaaaagaga
     6601 tgactgaaaa aagactgacc tgggatgagt attttgcagc ccaagcccta ctaattgcga
     6661 atcgttccac ttgtaaacgt gctaaagtgg gcgcgattct ggtaaaagat aataaggtta
     6721 tttccactgg ttacaatggt tcggtgtcag ggactgagca ttgtattgat cacgaatgtt
     6781 tggtcattga aggccactgt gttcgcaccc ttcacgctga ggtcaatgct atccttcaag
     6841 gtgctgagcg tggtgttccc aaaggcttta cagcctatgt aacccatttt ccttgtctca
     6901 actgtacaaa acaattgctt caggtcggct gcaagcgtgt ggtttatatc aaccagtacc
     6961 gaatggacga ctacgcccaa tacctttatc aagaaaaagg gacagaattg acccatttac
     7021 cacttgagac agtacagaca gctcttaaag aggctgatct aatgtaaaaa ttatcaaaaa
     7081 taaatggttt agaaagattt ttaaaccgtt ttttggtata ataagaagaa taaattgaaa
     7141 gaaggaattc caaaaatggg aaaaattgaa gttattaatc acccactgat tcaacacaaa
     7201 ttgtcaatct tgcgtcgtac agatacttct acaaaagctt ttcgtgagct agtagatgag
     7261 attgcaatgt tgatggggta tgaagtactt cgtgatcttc cactagaaga tgtggaaatc
     7321 gaaacaccaa ttacaaaaac agttcaaaaa caattggcag gtaagaaatt ggccatcgtc
     7381 ccaatcttgc gtgcaggtat cgggatggtt gatggtctct tgagcttggt tccagctgct
     7441 aaagttggcc acatcggtat gtaccgtgat gaagaaacac ttcaaccagt tgaatacttg
     7501 gtgaaattgc ctgaggacat tgaccaacgt caaatttttg tagtagaccc aatgttggca
     7561 acaggtggct cagcaatctt ggctgttgat tctcttaaaa aacgtggcgc atcaaatatc
     7621 aaatttgtct gccttgtatc tgctccagag ggtgtaaaag cccttcaaga agctcatcca
     7681 gatgtagaaa tctttacagc agccttggat gaacgtttga acgaacacgg ttatatcgtt
     7741 ccaggtcttg gagatgctgg agaccgcttg ttcggtacaa aataagatcg aaaagaagaa
     7801 tgacttggaa aagtatttcc agtcacgaaa ggaggttggg tttttgtttc tgtctaatga
     7861 aagcagagca aaaatttgac cttttttgac caagatatta taatagtctt atcttcagtc
     7921 atttgaccaa caaaattaaa actcaaaagg agaaatgaat gattcctgta gttattgaac
     7981 aaacaagccg tggagaacgt tcttacgata tttactcacg tcttctcaaa gaccgcatca
     8041 ttatgctgac aggtccggtt gaagacaata tggctaactc tgttattgcc caattgcttt
     8101 tcttggatgc ccaagatagt acaaaagata tttaccttta tgtcaataca ccaggtggtt
     8161 ctgtttcagc tggtttggca atcgtagata ccatgaactt tatcaaggca gatgtccaaa
     8221 ccattgttat gggaatggct gcatctatgg ggactgtcat cgcatcaagt ggagcaaaag
     8281 gcaaacgttt catgcttcca aatgctgaat acatgattca ccaaccaatg ggcggtacag
     8341 gtggtggtac ccaacaaact gatatggcta tcgctgcaga acacttgctc aaaactcgta
     8401 ataccttgga aaaaatcttg gctgaaaatt caggtcagtc aatggaaaaa gtccatgcag
     8461 atgcagaacg tgataactgg atgagcgccc aggaaacact tgaatatggc tttattgatg
     8521 aaattatggc caacaattca ttgaactaat gatgatagaa ggcaaactcg actgggtttg
     8581 ctttttttgg tataataggg agagatttct tagaaagagg atttatcatg tttgaaaaag
     8641 tcaatcgctc tggcttgatt atctatcttt actataatcg tgatgccaaa aaactgcagg
     8701 attatggaga tattacctat cattccaaga aacatcgtta cttacaactc tatgttccaa
     8761 ctcaagaagt ggagcaattg gtcggacgct tgagcaagga aaaatttatt aaaaaagtta
     8821 gggtttgtca tatccaagag ttggaaacac cctttgtggg caatctttat cgataggaaa
     8881 acgttatcat cgaaaaaagc tcaaggaaaa cattgacaat tttctgataa ttcggtatat
     8941 tcttaacaga ctatttaaga aataaggaga caaaaagatg aagaaaaaat ttgccctatc
     9001 gtttgtggcg cttgcaagtg tagcacttct tgcagcctgt ggagaagtga agtctggagc
     9061 agtcaacact gctggtaact cagtagagga aaagacaatt aaaatcgggt ttaactttga
     9121 agaatcaggt tctttagctg catacggaac agctgaacaa aaaggtgccc aattggctgt
     9181 tgatgaaatc aatgccgcag gtggtatcga tggaaaacaa atcgaagtag tcgataaaga
     9241 taataagtct gaaacagctg aggctgcttc agttacaact aaccttgtaa cccaatctaa
     9301 agtatcagca gtcgtaggac ctgcgacatc tggtgcgact gcagctgcgg tagcgaacgc
     9361 tacaaaagca ggtgttccat tgatctcacc aagtgcgact caagatggat tgactaaagg
     9421 tcaagattac ctctttattg gaactttcca agatagcttc caaggaaaaa ttatctcaaa
     9481 ctatgtttct gaaaaattaa atgctaagaa agttgttctt tacactgaca atgccagtga
     9541 ctatgctaaa gggattgcca aatctttccg cgagtcatac aagggtgaaa tcgttgcaga
     9601 tgaaactttc gtagcaggtg acacagactt ccaagcagcc cttacaaaaa tgaaagggaa
     9661 agactttgat gctatcgttg ttcctggtta ctataatgag gctggtaaga ttgtaaacca
     9721 agcgcgtggc atgggaattg acaaaccaat cgttggtggt gatggattca acggtgagga
     9781 gtttgtacaa caagcaactg ctgaaaaagc atcaaacatc tactttatct caggcttctc
     9841 aactactgta gaagtttcag ctaaagctaa agccttcctt gacgcttacc gtgctaagta
     9901 caatgaagag ccttcaacat ttgcagcctt ggcttatgat tcagttcacc ttgtagcaaa
     9961 cgcagcaaaa ggtgctaaaa attcaggtga aatcaaggat aaccttgcta aaacaaaaga
    10021 ttttgaaggt gtaactggtc aaacaagctt cgatgcagac cacaacacag tcaaaactgc
    10081 ttacatgatg accatgaaca atggtaaagt tgaagcagca gaagttgtaa aaccataata
    10141 gaaaaatgtt gaaataggga atgagccttt gactcactcc ctgtttcgat atttaatact
    10201 cttcgaaaat ctcttcaaac tgcgtcaacg tcgccttgga ttatatatgt gactgacttc
    10261 gtcagtctta tctacaacct caaagcagtg ctttgagcaa cctgcggcta gtttcctagt
    10321 ttgctctttg attttcattg agtataagaa cctatcaaaa agtgagggaa aaccttcgga
    10381 attataaata gaaagagtga atcttatgct ccaacaactc gtaaatggtt tgattctagg
    10441 tagtgtttac gcgctgttag ccctaggata taccatggtt tacggaatta tcaagctcat
    10501 caacttcgcc catggtgata tttatatgat gggagccttt atcggttatt tcttgatcaa
    10561 ttctttccaa atgaatttct ttgtagcgct tattgtagct atgctagcga cagctattct
    10621 tggtgtcgtg attgagtttc ttgcttaccg acctttgcgc cactctactc gtattgctgt
    10681 tttgattacg gctattgggg tttctttcct attggagtat ggaatggtct atctggttgg
    10741 tgccaatacc cgtgccttcc ctcaagcgat tcaaacagtt cgatatgatt tgggaccaat
    10801 tagcttaaca aatgtgcagt taatgatttt ggctatttcc ttgattttga tgattttgtt
    10861 acaagtcatt gtccaaaaga ctaagatggg gaaagccatg cgtgcagtat cagtagatag
    10921 cgacgcggcg caattgatgg ggatcaatgt aaaccgtacg attagcttta ccttcgcttt
    10981 gggttctgct cttgcgggtg cggctggtgt tctgattgct ctttattata actctcttga
    11041 gcctttgatg ggggttactc caggtcttaa atctttcgtt gccgcagtac ttggtggtat
    11101 cggaattatt cctggtgcgg ctcttggtgg ctttgtgatt ggtctattgg aaacctttgc
    11161 gacagccttt gggatgtcag atttccgtga tgccattgtt tatggaatct tgttgttgat
    11221 cttgattgtc cgcccagctg gtatccttgg taagaatgtg aaagagaagg tgtaagcgat
    11281 gaaggaaaat ttaaaagtta atattctatg gttactcctt ttgttagctg gctatagctt
    11341 gattagtgta ctggtttcag tcggagtact taatctattc tatgtacaga ttttacaaca
    11401 aattggaatt aatattattt tggctgttgg tctcaactta atcgttggtt tttcaggaca
    11461 attttcactt ggtcatgctg gtttcatggc gattggtgcc tatgcagcag ctattattgg
    11521 ttctaaatca ccaacctacg gtgccttctt tggagctatg cttgtaggag ctttgctttc
    11581 aggagcagtt gccttacttg tcggcattcc aaccttgcgc ttgaaggggg actatcttgc
    11641 ggtagcaact ctaggtgttt ctgaaattat ccgtatcttt atcatcaatg gtggaagcct
    11701 tacaaatggt gcggcaggta ttttagggat tcctaacttt acaacttggc aaatggttta
    11761 cttctttgtc gtgattacaa ccattgcaac cttgaacttc ttgcgtagcc caattggtcg
    11821 ttcaaccctc tctgttcgtg aagatgaaat cgctgctgag tcagttgggg ttaatacgac
    11881 taaaattaaa atcatcgctt ttgtctttgg tgccattact gcaagtattg ctgggtcact
    11941 tcaggcagga tttatcgggt ctgttgtacc gaaagattac accttcatca actcaatcaa
    12001 cgttttgatt attgttgtat ttggtggact cggttccatt acaggtgcga ttgtttcggc
    12061 tattgttctg ggaattttga atatgcttct ccaagatgtt gctagtgtgc gtatgattat
    12121 ttacgctttg gccttggtat tggtaatgat tttcagacca ggtggactcc ttggaacatg
    12181 ggaactgagc ctatcacgtt tctttaaaaa atctaagaag gaggaacaaa actaatggca
    12241 ttacttgaag taaaacagtt aaccaaacat tttggtggtc taacagctgt tggagatgtg
    12301 actcttgaat tgaacgaagg ggaactggtt ggattaatcg gtccaaacgg agctgggaaa
    12361 accacccttt tcaacctttt gaccggtgtt tatgaaccaa gcgagggaac agtaacccta
    12421 gatggtcacc ttttgaatgg gaaatcacct tataagattg cctctttggg acttggacgt
    12481 actttccaaa atatccgtct ctttaaagat ttaacagttt tagataatgt tttgattgct
    12541 tttggaaacc atcacaaaca gcatgttttt actagtttct tacgcttacc agctttttac
    12601 aagagtgaaa aagaattaaa ggataaagct ttggaattgt tgaaaatctt tgatttagat
    12661 ggtgatgcag agactcttgc taaaaatctt tcctacggac aacaacgtcg tttggaaatt
    12721 gttcgtgccc ttgctacgga acctaaaatt ctcttcttag atgaaccagc agcaggtatg
    12781 aacccacagg aaacagccga attgactgag ttaattcgtc gtatcaaaga tgaatttaag
    12841 attacaatca tgttgattga acacgatatg aatctggtca tggaagtaac agaacgtatc
    12901 tacgtacttg aatatggccg tttaattgct caaggaactc cagacgaaat taagaccaat
    12961 aaacgcgtta tcgaagctta tctaggaggt gaagcctaat gtctatgtta aaagttgaaa
    13021 atctttctgt gcattacggt atgatccaag cagtccgtga tgtaagcttt gaagttaatg
    13081 aaggagaagt tgtttccctt atcggtgcca acggtgcagg taagacaact attcttcgca
    13141 ccttgtcagg tttggttcga ccaagttcag gaaagattga atttttaggt caagaaatcc
    13201 aaaaaatgcc agctcagaaa atcgtggcag gtggtctttc acaagttcca gaaggacgcc
    13261 acgtctttcc tggcttgact gttatggaaa atcttgaaat gggagctttc ttaaagaaaa
    13321 atcgtgaaga aaatcaagca aacttgaaga aggttttctc acgctttcct cgtcttgaag
    13381 aacgtaagaa ccaagatgca gctactcttt caggagggga acaacaaatg cttgccatgg
    13441 gacgcgctct tatgtcaaca ccaaaacttc ttcttttaga tgaaccatca atgggacttg
    13501 ccccaatctt tatccaagag atttttgata tcattcaaga tattcagaag caaggaacaa
    13561 ccgtcctctt gattgaacaa aatgccaata aagcactcgc aatctctgac cgaggatatg
    13621 tactggaaac agggaaaatc gtcctatcag gaacaggaaa agaactcgcc tcatcagaag
    13681 aagtcagaaa agcatatcta ggtggctaaa acaatccagt ggattgtttt agtcggcaga
    13741 tgaagattac gaagtaatca tcaatatagt ccgggggacc tttttagtcg gtagattgag
    13801 attgcaaaca aatctgcatc tacattgaaa gctgaatttc taataattga aaaaatcgaa
    13861 tgaaaagttt cttaccttca ttcacagaac tcgatttcag agctcttttg ctagcttatt
    13921 catacttttc tgaatttcga aaaagaaatg taagcgtttg atagatttgc aaaaagattg
    13981 tataataggg ataagaatag aaaaggagaa gtctcatggc agttaaagat tttatgaccc
    14041 gcaaggtagt ttatattagt ccagatacaa cagtatctca tgcagcagat ttgatgagag
    14101 agcaaggttt gcaccgtctg cctgttatcg aaaatgatca attagttggt ttggtgactg
    14161 agggaaccat tgcacaagca agtccatcta aagcaacaag tctttctatc tatgagatga
    14221 attatcttct gaataagaca aaagtaaaag atgtcatgat tcgcgatgtt gtcactgtct
    14281 caggctatgc tagtctagaa gatgcaactt atctgatgtt gaaaaataag attagtattc
    14341 tccctgtcgt agataaccat caagtatacg gagttattac tgaccgtgac gttttccaag
    14401 cctttcttga aattgcaggt tatggcgaag aagggattcg tgtacgcttt gttacagaag
    14461 atgaagttgg tgttcttgga aaaattgttt ctttgattgt agaagaaaat ttgaatatct
    14521 cccatacagt caatattccg cgtaaggatg gtaaggtgat tatcgaagtg caaatcgatg
    14581 gatcaattga tttaccagcc ttgaaagaaa aatttgaagc aaatggtatt caagtggaag
    14641 aaatcgctcg cacttcagca aaagtcttgt aagaagggaa gcccaaaggc ttcttttttc
    14701 atgaaaaggg gattagagaa aaagatggaa agaaatgata aaatatgcta taatgaaata
    14761 gtgtaaaaaa ggagtattta tggacatttc agtaattcgt cagaaaattg acgcaaatcg
    14821 tgaaaaatta gcttctttca gggggtctct ttgacctcga agggctagag gaagagattg
    14881 ccatcttgga aaacaagatg acagaacctg atttttggaa cgataatatt gcggcccaaa
    14941 aaacgtcgca agaattaaat gaattaaaaa acacttacaa taccttccat aagatggaag
    15001 agttgcagga tgaagtcgaa attttattgg attttttggc tgaagacgag tcagtgcatg
    15061 atgaactggt agcgcagtta gccgaacttg ataagataat gaccagctac gagatgactc
    15121 tactcttgtc agaaccttat gaccacaaca atgccatctt ggaaatccat ccaggttctg
    15181 gtggtactga ggcgcaggac tggggtgata tgttgcttcg tatgtatact cgttatggta
    15241 atgctaaagg ctttaaagtg gaagtgttgg attaccaagc aggtgatgag gctggtatta
    15301 agtcggtaac tttatcattt gaagggccta atgcctatgg tctcctcaag tcagaaatgg
    15361 gtgttcatcg cttagtgcga atctcaccat ttgactctgc caaacgtcgc catacctctt
    15421 tcacatctgt agaagtgatg ccagaattgg atgatactat tgaagtggaa atccgtgaag
    15481 atgatatcaa gatggatacc ttccgttcag gtggtgccgg tggacaaaac gtcaataaag
    15541 tttcaacagg tgtacgttta acccacattc caactggaat tgttgtccaa tcaacagtgg
    15601 atcgtaccca gtatggaaat agagatcgtg ccatgaagat gttgcaggct aagctctatc
    15661 aaatggagca agataagaag gctgcggagg tagattctct caaaggtgag aaaaaggaga
    15721 tcacttgggg aagccaaatc cgttcttatg tcttcacgcc ttatactatg gtaaaagatc
    15781 accgaactag ctttgaggtt gctcaggtag ataaggttat ggatggggac ctagatggtt
    15841 ttatcgatgc ttatctcaag tggcgaatta gctaagatag aaaggaactc acatgtcaat
    15901 tattgaaatg agagatgtcg ttaaaaaata cgacaacgga acgactgctc tacgcggtgt
    15961 ttcggtcagc gttcaaccgg gggaatttgc ttacatcgta ggaccttcag gagcagggaa
    16021 gtcaactttt attcgttctc tgtatcgtga agtaaaaatc gataaaggaa gtctatcagt
    16081 tgctggtttt aatctggtta agatcaaaaa gaaagatgtc ccgcttctac gtcgtagtgt
    16141 tggggttgtc ttccaagatt ataaattgtt accaaagaaa actgtctatg aaaatattgc
    16201 ttacgctatg gaagtaatcg gggaaaatcg ccgtaatatc aaaagacgag tgatggaagt
    16261 tttggacttg gttggattga agcataaggt tcgttctttc ccaaatgaac tctcaggtgg
    16321 ggagcaacag cgaattgcga ttgcgcgtgc aattgtaaat aatcccaaag tattgatagc
    16381 tgatgagcca acaggaaatc tggatccgga taattcatgg gaaattatga atctcttgga
    16441 acggattaac ctacaaggga caactatttt gatggcgact cataatagcc agattgtaaa
    16501 taccttgcgc caccgtgtca ttgccattga aaatggccgt gtcgttcgtg acgaatcaaa
    16561 aggagagtat ggatacgatg attagtagat tttttcgcca tttatttgaa gccttaaaaa
    16621 gtttgaaacg aaatggttgg atgacagtag ctgctgtcag ttcagtcatg attactttga
    16681 ccttggtggc aatatttgca tctgttattt tcaatacagc gaaactagct acagatattg
    16741 aaaataatgt ccgtgtagta gtttatatcc gaaaggatgt ggaagataat agtcagacaa
    16801 ttgaaaaaga aggtcaaact gttacaaata atgactacca caaggtatat gattctttga
    16861 agaacatgtc tacggttaaa agtgttacct tttcaagtaa agaagaacaa tatgaaaaat
    16921 taaccgagat aatgggagat aactggaaaa tctttgaagg agatgccaat cctctctatg
    16981 atgcctatat tgtagaggca aacactccaa atgatgtaaa aactatagcc gaagatgcta
    17041 aaaaaattga aggtgtctct gaggttcaag atggcggtgc caatacagaa agactcttca
    17101 agttagcttc atttatccgt gtttggggac tagggattgc tgctttgtta atttttatcg
    17161 cagttttctt gatttcaaat accattcgta ttaccattat ttcccgcagt cgcgaaattc
    17221 aaatcatgcg cttggtcgga gctaaaaaca gttatatccg tggaccgttc ttgttagaag
    17281 gagcctttat cggtttattg ggagctatcg caccatctgt tttggtcttt attgtttatc
    17341 aaattgttta ccaatctgtc aacaaatcgt tggtagggca aaatctatcc atgattagtc
    17401 cagatttatt tagtccgttg atgattgccc tactatttgt gattggggtt ttcattggtt
    17461 cattgggatc aggaatatcc atgcgccgat tcttgaggat ttaggtaaaa tagctgcttt
    17521 tatgaggaga ttgtaaaatc tccttttttg ctacaagagt ttttgaaaag agatgcgtag
    17581 aagaaaagag cttccaaaga agtcccccag agaagacttc ttgatggcta atttgaactt
    17641 gaaatttggc gcactagaaa ttttttagaa aaaagtgtaa tttttttata aaagccttta
    17701 caaaaaaaat taaagtggta taattaaatc atagaaggtg caaacgtttt cgtaaaacgt
    17761 ttgcctaaat aaaaataaag gagatttgaa tgatgaaaga tacattcaaa aatgtcttgt
    17821 ctttcgaatt ttggcaaaaa ttcggtaagg ctttgatggt agttatcgcg attatgccgg
    17881 ctgctggttt gatgatttca atcggtaagt ctatcgtgat gattaaccca acctttacac
    17941 cacttgtcat cacaggtgga attcttgagc aaatcggttg gggggttatc ggtaaccttc
    18001 acattttgtt tgccctagcc attggaggaa gctgggctaa agaacgtgct ggtggtgctt
    18061 tcgccgctgg tcttgccttc atcttgatta accgtatcac tggtacaatt tttggtgtat
    18121 caggcgatat gttgaaaaat ccagatgcta tggtaactac tttctttggt ggttcaatca
    18181 aagttgctga ttactttatc agtgttcttg aagctccagc cttgaacatg ggggtattcg
    18241 tagggattat ctcaggtttt gtaggggcaa ctgcttacaa caaatactac aacttccgta
    18301 aacttcctga tgcactttca ttcttcaacg ggaaacgttt cgtaccattt gtagttattc
    18361 ttcgttcagc aatcgctgca attctacttg ctgctttctg gccagtagtt caaacaggta
    18421 tcaataactt cggtatctgg attgccaact cacaagaaac tgctccaatt cttgcaccat
    18481 tcttgtatgg tactttggaa cgtttgctct tgccatttgg tcttcaccac atgttgacta
    18541 tcccaatgaa ctacacagct cttggtggta cttatgacat tttaactggt gcagctaaag
    18601 gtactcaagt attcggtcaa gacccactat ggcttgcatg ggtaacagac cttgtaaacc
    18661 ttaaaggtac tgatgctagt caataccaac acttgttaga tacagtacat ccagctcgtt
    18721 tcaaagttgg acaaatgatc ggttcattcg gtatcttgat gggtgtgatt gttgctatct
    18781 accgtaatgt tgatgctgac aagaaacata aatacaaagg tatgatgatt gcaacagctc
    18841 ttgcaacatt cttgacaggg gttactgaac caatcgaata catgttcatg ttcatcgcaa
    18901 cacctatgta tcttgtttac tcacttgttc aaggtgctgc cttcgctatg gctgacgtcg
    18961 taaacctacg tatgcactca ttcggttcaa tcgagttctt gactcgtaca cctattgcaa
    19021 tcagtgctgg tattggtatg gatatcgtta acttcgtttg ggtaactgtt ctctttgctg
    19081 taatcatgta ctttatcgca aacttcatga ttcaaaaatt caactacgca actccagggc
    19141 gcaacggaaa ctacgaaact gctgaaggtt cagaagaaac cagcagcgaa gtgaaagttg
    19201 cagcaggctc tcaagctgta aacattatca accttcttgg tggacgtgta aacatcgttg
    19261 atgttgatgc atgtatgact cgtcttcgtg taactgttaa agatgcagat aaagtaggaa
    19321 atgcagagca atggaaagca gaaggagcta tgggtcttgt gatgaaagga caaggggttc
    19381 aagctatcta cggtccaaaa gctgacattt tgaaatctga tatccaagat atccttgatt
    19441 caggtgaaat cattcctgaa actcttccaa gccaaatgac tgaagcacaa caaaacactg
    19501 ttcacttcaa agatcttact gaggaagttt actcagtagc agacggtcaa gttgttgctt
    19561 tggaacaagt aaaggatcca gtatttgctc aaaaaatgat gggtgatgga tttgcagtag
    19621 aacctgcaaa tggaaacatt gtatctccag tttcaggtac tgtatcaagc atcttcccaa
    19681 caaaacatgc ttttggtatt gtgacggaag caggtcttga agtattggtt cacattggtt
    19741 tggacacagt aagtcttgaa ggtaaaccat ttacagttca tgttgctgaa ggacaaaaag
    19801 ttgcagcagg agatctcctt gtcacagctg acttgaatgc tatccgtgca gcaggacgtg
    19861 aaacttcaac agtagttgtc ttcacaaatg gtgatgcaat taaatcagtt aaattagaaa
    19921 aaacaggttc tcttgcagct aaaacagcag ttgctaaagt agaattgtaa tatacttgag
    19981 gttggaagct gtattccaac ctcttatttt gggagaaaag aatgaaattt ttaacactca
    20041 atactcacag ttggatggag aaagaagcag aggaaaaatt ccagattttg cttgaagata
    20101 ttcttgaaaa ggactatgat ttgatttgtt ttcaagaaat caatcaggag atgacctcgt
    20161 cagaggtgga ggttaatgac ctttatcaag ctttgccagc agctgagcct attcaccaag
    20221 accattatgt tagactcttg gttgaaaagt tgttagagca agggaaaaat tactactgga
    20281 cctgggctta taaccatatc ggctatgacc gctaccacga aggtgtggct atcttgtcta
    20341 aaacacctat tgaagccaga gaaattttgg tttcagatgt ggatgatcca acagactatc
    20401 atactcgccg tgttgcccta gctgaaactg tagtcgatgg caaggagcta gcagttgcca
    20461 gtgttcatct ctcttggtgg gataaaggtt tccaagaaga atgggcacga tttgaggctg
    20521 tcttgaaaaa attgaacaag ccacttttac tagctggaga ttttaacaac ccagcaggtc
    20581 aggaaggtta ccaagctatt ttagctagtc cattaggctt acaagacgca tttgaagttg
    20641 ctcaagagaa aagtggtagc tatactgttc cgcctgaaat tgatggctgg aaagggaaca
    20701 ctgaacccct tcgaatcgat tatgtcttta ctaccaaaga gttagcggtg gaaaatttac
    20761 atgtcgtatt tgatggtaac aagagtccac aagtgagtga tcactatggc ttgaatgcgg
    20821 tattaaattg gaaataaaat caaaaaatga aagggagcga gtcctttcat ttttttacaa
    20881 aaatccctat aattactatt ttggagaagg agttttttgt atatttgtat attatgagga
    20941 aatatccaca aataagtttt taaaacttta cggtcaaaaa aaaatcgcta atattaacta
    21001 tttatgatag aatgaaaatt atgaaataaa aggaggactg gaatgttttt tcaggataga
    21061 aagataaaat attcaatccg caaattgtca gttgctactg tgtcccttgc gattggattt
    21121 ttgtttgcgc ctgcggcgct tggagtcgct caagtagctc aagctgatga gctttcaact
    21181 actgaacaag tggagaataa agcagagaat caggtctcgg tggtctcttt tgcaacagag
    21241 caagaagaaa gtgaaacgac ttatgttgat acgacgaata aagtgacttg gacatttgca
    21301 ggatacgata aagaaaaaat tgttgtagga aaaggcagac agactttcct tggaagctgg
    21361 gtacctactc caaatccaga atatgtattc aaatcatcta aagcaggtgt tccattacca
    21421 caaagtattt tgggaatgct tccaaaggat gaagcttctt ataaggttgg tgacaccatt
    21481 gtagccaaac aacctgctgt agaatcagta gtcgaagaag aaaaagacta tgtctggacc
    21541 ttcaaaggtt atgatcagaa gaatgcgacg tacaatggca agcgtgtgac atttacaggt
    21601 atctgggaag taacgcctag accgcatcat gtaagctata cttttgtaag tgttacat
//
LOCUS       DAVLDI010000039        21385 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLDI010000039 DAVLDI010000000
VERSION     DAVLDI010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21385
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.039"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            159..2206
                     /locus_tag="VXD01_001503"
                     /pseudo
     CDS             159..2206
                     /locus_tag="VXD01_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            2217..3578
                     /locus_tag="VXD01_001504"
     CDS             2217..3578
                     /locus_tag="VXD01_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV0601876.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPIITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            3635..3790
                     /gene="blpC"
                     /locus_tag="VXD01_001505"
     CDS             3635..3790
                     /gene="blpC"
                     /locus_tag="VXD01_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV0601877.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(3835..5175)
                     /locus_tag="VXD01_001506"
     CDS             complement(3835..5175)
                     /locus_tag="VXD01_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0601878.1"
                     /translation="MNIVWILLHTLITNGLEIVIFFKVDGINLTFERIFKAFLLKILL
                     VFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYALFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLKDSSKKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(5189..5926)
                     /locus_tag="VXD01_001507"
     CDS             complement(5189..5926)
                     /locus_tag="VXD01_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0601879.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(5931..6269)
                     /locus_tag="VXD01_001508"
     CDS             complement(5931..6269)
                     /locus_tag="VXD01_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0601880.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     VQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            6545..6874
                     /locus_tag="VXD01_001509"
     CDS             6545..6874
                     /locus_tag="VXD01_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0601881.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7042..8091)
                     /locus_tag="VXD01_001510"
     CDS             complement(7042..8091)
                     /locus_tag="VXD01_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0601882.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     QVLYLPYQVKRQMQD"
     gene            complement(8088..8819)
                     /locus_tag="VXD01_001511"
     CDS             complement(8088..8819)
                     /locus_tag="VXD01_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0601883.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            8887..9297
                     /locus_tag="VXD01_001512"
     CDS             8887..9297
                     /locus_tag="VXD01_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV0601884.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9307..9594
                     /locus_tag="VXD01_001513"
     CDS             9307..9594
                     /locus_tag="VXD01_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601885.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(9916..11052)
                     /gene="dnaJ"
                     /locus_tag="VXD01_001514"
     CDS             complement(9916..11052)
                     /gene="dnaJ"
                     /locus_tag="VXD01_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV0601886.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGDGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(11454..11810)
                     /locus_tag="VXD01_001515"
     CDS             complement(11454..11810)
                     /locus_tag="VXD01_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV0601887.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(11812..13635)
                     /gene="dnaK"
                     /locus_tag="VXD01_001516"
     CDS             complement(11812..13635)
                     /gene="dnaK"
                     /locus_tag="VXD01_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV0601888.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14115..14639)
                     /gene="grpE"
                     /locus_tag="VXD01_001517"
     CDS             complement(14115..14639)
                     /gene="grpE"
                     /locus_tag="VXD01_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV0601889.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSKLDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(14666..15700)
                     /gene="hrcA"
                     /locus_tag="VXD01_001518"
     CDS             complement(14666..15700)
                     /gene="hrcA"
                     /locus_tag="VXD01_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV0601890.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(15864..16301)
                     /locus_tag="VXD01_001519"
     CDS             complement(15864..16301)
                     /locus_tag="VXD01_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV0601891.1"
                     /translation="MHLKGWRYRTSRFGLFYFDQCQPDDVIYRIYDSRFLKKYKHELQ
                     DFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMSKGLKWEVMRSRLRSCTTTFLGGLV
                     VCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFRLKRKYRVDE"
     gene            16981..17281
                     /locus_tag="VXD01_001520"
                     /pseudo
     CDS             16981..17281
                     /locus_tag="VXD01_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818342.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
     gene            17401..19314
                     /locus_tag="VXD01_001521"
     CDS             17401..19314
                     /locus_tag="VXD01_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0601892.1"
                     /translation="MTKEKGLTYEITEAISTPYYTDAFSMKTPRYYQQIAINRTIETV
                     ARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLAKRVLFLADRNILVDQTMAEDFRPF
                     EKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAH
                     RGSAKENSNWRKVIDYFSSATQIGMTATPKETKNASNMEYFGEPIYTYSLKQGIEDGF
                     LAPYRVMRVNLDVDVGGYRPETGKVDANGQLIEDRYYGRKDFDKTIVIDDRTQRVAKF
                     VSDYMKQNNARFDKTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGK
                     AQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLY
                     PQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLETGAKTVSGSTPGFVDEEGDPVEKY
                     IVTDKQVTILNSTVQVLDENGKLITESLTDYTRKNILGSYATLNDFITVWHTADKKKL
                     ILDELYKKGVYLDAIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLY
                     KYSEEARAVLEILLNKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQ
                     AIKELEQELFTVA"
     gene            19327..20790
                     /locus_tag="VXD01_001522"
     CDS             19327..20790
                     /locus_tag="VXD01_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0601893.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            20790..>21385
                     /locus_tag="VXD01_001523"
     CDS             20790..>21385
                     /locus_tag="VXD01_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0601894.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLK
                     NIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLLSDN"
BASE COUNT         6816 a         4335 c         3942 g         6292 t
ORIGIN      
        1 gcttttcatt tgaaaccacc tctaaatttt ttaaaaaaag ataatttcta attatttttt
       61 accattcagg aagtttcaat gactattcaa gatttaataa aatatgaact tatttttatg
      121 gcataatata cctatctact atatgaaagg aattgccaat gacttcttat aaacgtacat
      181 ttgttcctca aatagatgcg agagactgcg gtgttgctgc cttagcctcg attgctaaat
      241 tctatggttc agatttttct ctagctcact tgagagaact tgcaaagacc aataaagaag
      301 ggacgactgc tcttggcatt gtaaaagccg ctgatgaaat gggctttgaa acaagacctg
      361 ttcaagcaga taaaacgctc tttgacatga gtgatgtccc ctatccattt atcgttcacg
      421 ttaacaaaga aggaaaactc caacattact atgttgtcta tcaaacaaag aaagactatc
      481 tgattattgg tgatcctgac ccttctataa aaatcactaa aatgtcaaaa gaacgctttt
      541 tctctgaatg gactggagta gctatttttc tagctcccaa acccagctat caaccccata
      601 aagataaaaa gaatggtcta ctaagcttcc ttcctctgat tttcaaacaa aaatctctca
      661 ttgcttacat tgttctctca agcttattgg tcactattat caatatcggt ggttcttatt
      721 atctccaagg aatcttagat gaatacatcc caaatcagat gaaatcaact ttaggaatca
      781 tctcagttgg tctggttatc acctatatcc tccaacaagt catgagcttc tccagaaatt
      841 aagcattgat gtgattttat cctatattcg ccatattttt gaacttccca tgtctttctt
      901 tgcgacacgt cgtacaggag aaatcatttc acggttcaca gatgctaact ctattataga
      961 tgccttggct tctacccttc tttctcttat ttccattcct atatacatgt tcatcatctt
     1021 ttcttttatg aaacctttcg aaaaaatgaa ccatgatgtc atgcaaagta attctatggt
     1081 tagctctgcc attatcaaag atatcaacgg gattgaaact ataaagtcgc tcacgagtga
     1141 agaaaatcgc tatcaaaata tagacagcga atttgtagat tatttggaaa aatcctttaa
     1201 gctcagtaaa tattctattt tacaaacgag tttaaagcag ggaacaaaat tagttctgaa
     1261 tatccttatc ctatggtttg gcgctcaatt agtcatgtca agtaaaattt ctatcggtca
     1321 gctgattacc tttaacacac ttttttctta ctttacaact cctatggaaa atattatcaa
     1381 cctccaaacc aaactccaat ctgcgaagat cgctaataac cgtttgaacg aagtctatct
     1441 agtcgaatct gaatttcaag ttcaagaaaa ccctgttcat tcacattttt tgatgggcga
     1501 tattgaattt gatgaccttt cttataagta tggttttgga cgagatacct taacagatat
     1561 taatctcacg attaaacaag gagataaggt tagcctagtt ggagttagtg gttctggtaa
     1621 aacaacttta gccaaaatga ttgtcaattt ctttgaaccc tacaaagggc atatttccat
     1681 caatcatcag gatattaaaa acattgataa aaaagtcttg cgccgtcata ttaattacct
     1741 accccaacaa gcctatatct ttaatggctc tattttggaa aacttaacct tgggcggtaa
     1801 tcatatgatt agtcaagaag atattctaaa agcttgtgaa gtagctgaaa tccgtcaaga
     1861 cattgaaaga atgcctatgg gctatcaaac tcagctctct gatggagctg gtctatcagg
     1921 aggacagaag caacgaatcg ccctcgctcg tgctctttta actaaatctc ctgttttaat
     1981 actagatgaa gctactagcg gtcttgatgt cttgactgag aaaaaggtta tagataatct
     2041 tatgtcccta actgataaaa ccattctctt tgtagcccat cgtctcagta tagccgaacg
     2101 aactaaccgt gtcattgttc ttgaccaggg gaaaatcatt gaagttggta gtcaccaaga
     2161 gttaatgcag gcgcaaggct tctaccatca tctattcaat aaataaggag aatgtcatga
     2221 atcctaatct ttttagaagc gtcgagtttt atcagagacg ttaccataac tatgcgacag
     2281 tgttaattat acctctttca ttactgttta ctttcatctt gattttctcc cttgttgcca
     2341 caaaagaaat tactgttact tcccaaggag aaatcgcccc tacaagtgtc attgcatcta
     2401 ttcagtcgac cagtgataat cctatccttg ctaatcattt agtggcaaat caagtagttg
     2461 agaaaggtga cttactcatc aaatactctg aaacaatgga agagagtcag aaaactgcct
     2521 tagaaactca attacaaagg cttgagaagc aaaaagaagg acttggaatc ttgaaacaaa
     2581 gcttagaaaa agcgactgat cttttttcta gcgaggatga gtttggctac cataatacct
     2641 ttatgaattt tactaaacaa tcccatgata ttgaactggg tatctcaaag actaacactg
     2701 aagtttcaaa tcaagctaat cttaccaata gcagttcatc agccatcgaa caagaaatta
     2761 caaaagttca acaacaaatt ggagaatatc aagagctgag agatgctatc gtaaataaaa
     2821 gagctcgctt accaactggc aatccgcacc agtcaatttt aaatcgttat cttatagcct
     2881 ctcaagaaca aacacaagga acggcagagg agccattttt atctcaaatt aatcaaagta
     2941 ttgcaggtct ggaatcatct atcgcaagcc tcaaaattca gcaagctggc atcggaagtg
     3001 tagcaactta tgataatagt ttagcaacca aaattgaagt actccgcact cagtttttac
     3061 aaacagcctc tcagcaacaa ctaaccgtgg agaatcaatt aacagaatta aaagtacaac
     3121 tagatcaagc gacacagcgc ttagaaaaca ataccttaac cgctccaagt aaaggtatcg
     3181 ttcatctgaa cagcgaattt gaaggtaaaa atagaattcc aactggtaca gaaattgctc
     3241 aaatattccc tatcatcaca gatacaagag aagtactaat cacttactac gtatcttctg
     3301 actatctacc tctactagat aaaggacaaa ctgtaagatt aaaactggag aagattggaa
     3361 atcacggcac caccatcatc ggccaacttc agacaattga tcaaactcct accagaacag
     3421 agcaaggtaa tctctttaaa ttaaccgctc ttgcaaaact atctaatgag gatagtaaac
     3481 tcatccaata tggcttacaa ggtcgcgtca ctagtgtaac tgcaaagaaa acatattttg
     3541 attatttcaa agataaaatt ttaacccatt ctgattaatt ttcagataac actctataac
     3601 tatttattat cttatcaaaa aggagaatca taacatggat aagaaacaaa acctaacttc
     3661 atttcaagaa ctaacaacta ccgaactcaa ccaaattaca ggtggaggac tgtgggaaga
     3721 tatcttatac agccttaata taattaagca taacaatacg aaaggacttc atcatccaat
     3781 acaactataa aaaataagac cgagtaacaa gaactctcgg tcttattttt ttcatcattc
     3841 tgtaggtatc atagtaagca cctgacgaaa gacttgatct tgacaggtag tatttaaact
     3901 ggcattggga taactttcca caatcttcat aacggtatag agaccgacac ctctctcctc
     3961 ccctttagaa ctaactccaa aggagaagat ttcagaaata tcgatgccct cttctttgat
     4021 ggaattttcg atgatgaagg tctcctgtgc tccacttttt aaaaaggcaa ttgaaacatg
     4081 aggttgaccg gcctctgcac tcgcttcaat agcattatca caaaggatag acacaatggt
     4141 tagaaaatca agcagtctca tcccctcaac ctgaatctct tcaggaactt cgacattaaa
     4201 gacaatgtcc ttttctctag cttttataaa ttttccagct aggagacttt tgagggcacg
     4261 atcccgaaca ttcaccaatc ggcccaggtc atatttattg tcctgcaatt ttttactaga
     4321 atcctttaag accaagtcat agacctcttt tatctgctcc atatcctcct cttcaatacc
     4381 cagacgtaaa cttgtcaaga ggttggtgta gtcatggcga aaactcctta cttccttgta
     4441 aagttcctct atatgccgac tatagcgttc catatctcta tagcgcaaga cctgctcttg
     4501 gtccagtcta tcatggagtt tgtccttcaa ataggtatcc aatttcttga taacccccat
     4561 aaaaaatagg aggtagaaca ctaggatgag atggcgaaca gtcgttgatt gaataccttg
     4621 ctcatattca aagtaagaca gactttgtat caccaaatag taagccccca ttatccagtt
     4681 aatcttagtc agggactttt gaaaacctgt atctagaatc tcccttctca aactagtaaa
     4741 atcatagtcc aaccatttca aaaaggctag agaaatgaag aaattgaaaa ttattataca
     4801 taacccagta aatgagtagc catcatatac ttgcccttgt cccaaaaatg gaagcacaaa
     4861 ataggagact cctctataaa agagattcac caatatcatt ggaaagagag cataaaagaa
     4921 aaggagtttt ttaggaagcc ctcttaacaa taagaaagac aagcctatgc cgtacaaggg
     4981 ttccataaaa taagataggt aaacatttcc tactatatag ctaatcatta caaaaacaaa
     5041 gaccaacagt atcttcaaaa gaaaggcctt aaaaatcctc tcgaaagtaa gattaattcc
     5101 atccacctta aagaaaatga caatttctag cccattagta ataagtgtat gcaataatat
     5161 ccaaacaata ttcataaact ctcctagttc agtgtaagtt attaatagcc tcagacactt
     5221 ccctgacctt ataacgggcg attagacaac ttcctccatt gggaaagaaa agcagttttt
     5281 ctttcttatc caaatgcacc acatttgcag gattgatgag aaaggagcga tggcactgca
     5341 aaagacgagg ttcctgctta aaaacctcct ctaaactcgc tgtaaattcc agcctgtctg
     5401 tcttggtata gagaataaca cgatggggtc ttggggatgt ttcgagatag taaacctctt
     5461 taaaaggata ctggaattgg gcaaattttg atttaaagta aaagcaatct tccgccagac
     5521 ttttactatc ttgactattg gcatagagga gggctgtctc gattcgagat tcaaactcct
     5581 ctgccgaaag ggccttatca atatagtcca gagcagacac ttggtagcga aaggacaggg
     5641 gcataaactc cgagtgagtc gtcacaaaga caatcagggc ataggggtct cgatcccgaa
     5701 tctttctagc cacttccagc cccttcatct cctcatttcg aatctcaata tccaaaaaga
     5761 atagctgatg ggcccccttc tcatgcacct ctgccagcag ttggtctggc ttgccaaata
     5821 cctcaaaaga gctgggagtg atatgatgtt ccttcaagag tttctcaatc gtcgtttcaa
     5881 tcctagtctg ttgggaaaaa tcatcctcta aaacaaatat tctcatcttc ttactctccc
     5941 tctttcaacc atttttgacg aatttctcta tagcgacgtc tggcatactt gacagcgtat
     6001 tgaccttctt ctccgagaaa aaggattctt tcttgaaaat caatcgattt taatttatca
     6061 agattaacta aacaatttcg atgacatctc atcaaggttt ccccacattg gttctcaaga
     6121 ttacttaaat tttgaaccat attaaaacta gctttttctg taacaatctg tacggtatgg
     6181 gctttagttg gatgtgtttg gatatagtag atatcgtcga tgtttacttt atagactgtt
     6241 ttctgtgtct gaataatcat atgtttcatt ggattctcct cctaagaaaa gaataacaga
     6301 aaaggtctag cccaagccca cccaatccta aacagtcttt gaaaactcct aaaaggatta
     6361 ttttctacaa catcatgatg agcttacaac tattttatca taaaattcac tcagcgcaat
     6421 tcaagacatt tcaatgacaa ttaaagattt gaataaaaaa aaagaattaa aagtgataaa
     6481 ctaacagtat caaaacacag ttgccagaag taagactggc acccagatta aaggaggcat
     6541 tcccatgaca gatacagacc ccatcaaaag agctcatact ttgattactg acttaaacaa
     6601 agcctaccaa gcatgcaaac aggcaagcgc tgacgacgtc cgctttcagg agcaattaaa
     6661 ctctattctt ggttttctag ccaaggctga aacagtggat aatcgattct tgattgaatt
     6721 ggaaaaattt taccagactt ccagtcttct catgggactc agcgctcttg atccagatgc
     6781 tccaactcgc gccgcttggc gggcctatga ccgcttccac tttgaccaag tcaagaccaa
     6841 gttaatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaagc tgtacttgag
     6901 tacggtaaga cgacgctgac gtggtttgaa gagattttcg aagagtataa gtctctacgg
     6961 accaaccatt atcctgtagt aacaaaaaag aagctgagac agactgaact caacttcttt
     7021 tttagtgtcg tatcagcaat gttagtcctg catctgacgt tttacctgat aaggcaaata
     7081 caagacttgt aaaaccaaac cagctcccag taaggctaga agggctagtt tttcttgaaa
     7141 ggtaatcaac ccaacaacta attccacaag taaaacaaaa ctggtcaatc ctcgaactac
     7201 ctcctgtaag cctttttcct tttgcccctt gtccagcgga aagagttggg tcaaatactg
     7261 gtagtcaaag gcatgataga gggccagcaa ctggaagagc aagaggtagt taaagagaac
     7321 taccactgct gtcgcaatcc aagcttgctc gataaaaacc tgcgccagta cggaaagtaa
     7381 gagaagacga agactgagag caaagaggtc gccatttcgc agataagaac gcagatagag
     7441 attttgccaa atcttcccag gcaccttctg aacagccttt aagataaagt ccagataggc
     7501 acgacgctta acgctgtttg aaattccctt gacctgcgta aagagggcaa agaaacgaag
     7561 caagacttgc ttacgcttgc tttcttgaga aataacatag tcccagtcca gtccagtttc
     7621 agtgaaaaat ttgctggcct tttgacgaaa gtggaaatat tttcctaccc ccaataaaag
     7681 cacatagagc agaaaaactg gcaagccata acccattgct aaaaataaag gcgcaaataa
     7741 cagcaagaaa agggtctgta caaagagcca aaagactagg gaaatgccag tttgacgctt
     7801 gagatggagc ttgatttcct cttctccaac taagagaaag agcttgtctg gagcctccat
     7861 ataggtggca attcctcccc aaagtaaaag taaaacagac gtaattccta caaacaaaag
     7921 gataggccaa tgattttcag gaaaatgttg taagagttga ctgtactggt aggctagaaa
     7981 gcccaacagg acaagcagga acaagacaaa gtggtcattg agcacatagc gcagataacc
     8041 aagacactcc ttacgaaagg cctgctttct ctttaaaaac aagtctttca taggtcctcc
     8101 tcttttgtca gagccaagta aatatcattc aaactagcct caggcatatc aaaggcttcg
     8161 cgtagttgca ggagattgcc tttggcacgc acctctccct tgtgaagaat gacaaaggca
     8221 tcacacatct tctccgccga atccagcacg tgggtactca tgagaataga cttgcccttt
     8281 tgcttctcca cttccaaaag ctgaatcaaa tcagaaatag ctagcggatc aagaccaagg
     8341 aaaggctcat ccacgatgaa aagacttgga tccaccacaa aagcacagat aatcatgacc
     8401 ttctgcttca tcccttttga aaaatgaaca gggaaccagt ctaatttctg gtccagacgg
     8461 aacatcttta acaagggctc tactcgttcg aaagccactt tttgctcaat accgtaagcc
     8521 atagcaaccg tttcgatatg ctctctgagg gtcaattcct catacagact aggcgtctca
     8581 ggaatgtagc caatctgctt gcggtagcta gtcgcatctc cttgcagagt caggccattg
     8641 atattgatgg agccactata aggtgccaac agaccgataa tctcattgat cgtcgttgat
     8701 ttcccagcac cattgagacc aatcaaaccg accaactgcc cactttcaac agtaaaggac
     8761 acatctttca aaacaggaac atgaacatag ccacctgtca ggtttttaat ttctaacata
     8821 ttttctccaa atctggtata atgtagctat attatatcaa aattcagtac agtagaggta
     8881 gattttatgt cagattgcat tttttgtaaa atcatcgcag gggaaattcc tgcttcaaaa
     8941 gtatatgaag atgagcaggt ccttgccttt cttgatatct ctcaagtaac actaggacac
     9001 accttggtcg tgccaaaaga acactatcgc aatcttttgg agatggatgc tacgagcgcc
     9061 agccaactct ttgcccaagt accaaaagta gctcaaaaag tcatgaaagt cactaaggct
     9121 gctggtatga atatcatttc caactgtgaa gaagtcgctg gtcaaacagt ttttcatact
     9181 cacgttcacc ttgtgcctcg ctacagtgct gacgatgacc tcaagattga ttttatcgcc
     9241 cacgaaccag actttgacaa acttgctcaa gtcgctgaaa ccatcaaaaa cgcttaagga
     9301 gttgctatga aattatccaa cctactgcta tttgcaggag ctgcagccgg aagttatctg
     9361 gttacaaaaa atcgccaaac catcacagat gaagtcttga ataccactga ccgcgttcaa
     9421 gctatcaagg acgatgtgga tattatccaa aacagcctgc aaatcattaa ccagcaaaaa
     9481 gaacttatca aggaatacca agaagacttg acttacaagt ttaaggtctt ggaaaaggat
     9541 atccagacta gactagctgt gataaaagaa atgcagggaa ctgaagataa gtaaaaagag
     9601 ccccccggct cttttttaaa acgtaaacaa gttatagtga attgaattta gaatagcaca
     9661 ccatagtttc taaaacattg ttagagatta ctttaaaatc ctcttatcaa tttgttcata
     9721 ttctatttca atctattata tatatcccat caactatgca tcataattta ggtaactcat
     9781 actcaatgaa aatcaaaaag caaactagga aactagccac gggctgctca aaacactgtt
     9841 ttgaggttgt agatacgact cacatatata cggcaagccg acgctgacgt ggtttgaaga
     9901 gattttcaaa gagtattatt ctccatcaaa ggcatcttta atatgatcaa agaagccttt
     9961 tttctttgga tttactttca agtcaccagc agccgcgaat tctttcaagg ctactttttg
    10021 gcggtcgttc aagcctgtcg gtgttacgac attaacagta acgtattggt caccaactgc
    10081 accgccacga aggctcggtg cccccttact acgtaggcgg aatttcttac cagtctgagt
    10141 tccctctgga ataaccaatt caacatcacc gtgaacagtt ggaatatcta ctgtatcacc
    10201 aagagccgct tggacaaagt tgaggttgag attgtagaag atagtcgttc cttcacgttc
    10261 aaacttgtcg ctagcttcca cagaaactac tacatacaag tcaccataag gtccaccgtt
    10321 aaagcctgct tcaccttgac cagcgaggcg aatttgttga cctgtttcca caccagcagg
    10381 gattttcaca tgtacgctat gagcttgttt ctcatgacct gttccatgac aggttgtaca
    10441 tggatatttg atttcttttc cttggccgtg acagacatca caggttactt ggcgacgcat
    10501 cataccaaga ggagtctgcg tatcgacgtt aatgacacca gcgccatgac agcgtccaca
    10561 agtgactgga cttgtccctg gcttagcacc agagccatta catgtacgac agccagcttc
    10621 acgatgatac ttaacttcct tctcagttcc gaagatagct tcttcaaagg tcaaattgac
    10681 acgatactgg agatcatctc cttggcgagg agcgtttgga ttgcgcgaag aaccgcctcc
    10741 gccgaagaaa cttgagaaaa tatcctcaaa accaccgaag ccacctgccc cattgaaacc
    10801 gccgaaacca ccatctccac caaaaccacc attggcgcct gcagcaccat actggtcata
    10861 ggcagcacgt ttttggtcgt cactcaaagt ctcataggct tcttgaactt ccttgtactt
    10921 gtcctcagca ccaggctcct tgttgatatc tgggtgatat tttttggaaa gcttacgata
    10981 agcctttttg atttcgtctg ccgaagcgtt tttggatacc cccagacgat cataaaattc
    11041 agtattgttc ataattcaag atacaaaggg cgtcaaacgg acacagccat ctaggagttt
    11101 tgacgacgga cgcttatgtc ctagaaaaaa ctatcttttt ggcacagtcc gtagcccgtg
    11161 ttcagttacg aacaccctta ttcctttcta ttgatgttct gaatcgaacc accatttagg
    11221 tcggattcaa ttcctttctt ttatatttag taagaaattc tgaaacccgt gttcagttac
    11281 gaacactctt tgttcctttc tattgatgag acaaaaccca aacaaatgag attccgtccc
    11341 tttttatcga aaaacagagg ctgggttgca acctctgcaa ataagtaaat taactttatt
    11401 ttgattttaa atatcctata agtacagaaa tatttatata tttttgtctc ttcttagtat
    11461 ttgcctatat aattccaatt gatcataaga aatacaacta ctgtccaaat cataccaatt
    11521 atgaacggta ttacaaattt atatgtttgt atttctaatg atatcatagc tgataccatc
    11581 gccgatacaa atgcagacaa caatactgaa gtaacaaaat tccttaccgc ttcatcattt
    11641 ttgacacaac tatcatgctc agctaatata atttctctat atatagtcaa acattctact
    11701 ggaatattat ctataaaacc ttttgctgct tcatagttgt cagcttgatt acaaaaatca
    11761 ttataaactt ttcgtgtatt ttttagatac tcatcatcca atacactcat cttatttttc
    11821 cgtaaactct ccgtctacga cgtcatcgcc tgcgtttcct gttgcttgtg cgccttctgc
    11881 tccttcttga gcttgttgcg ctgctgcggc ttgttcgtag agtttcacag caaggccttg
    11941 agctttttcg ttcaacgctt caagtttcgc tttcatgtcg tccaagttgt tgtcttcttg
    12001 agctttctta aggtcatcaa gggcagcttg ggcagcgtca cgttctgcgt cgaagccttt
    12061 accttcagtt tccttgattg tcttttcagt cgcaaagatt gcttggtcta cttcattacg
    12121 aaggtctact tcttctttac gtttcttatc agcttcagcg tttgcttctg catctttcat
    12181 catgcggtcg atttcttcgt cagtcaaacc tgagttcgat tggatgacaa tagtttgttc
    12241 tttttgagtt ccaaggtctt tggccttaac agacacgata ccgttcttgt cgatgtcaaa
    12301 tgttacttcg atttgaggaa ttccacgagg tgcagctggg atatcagtca attggaagcg
    12361 tccaagagtc ttgttatctg ctgccattgg gcgttcacct tgaagaacgt ggatatcaac
    12421 ggctggttgg ttgtctgctg ctgttgagaa gacttgtgat ttagatgttg ggattgtagt
    12481 gttgcgatcg ataagttttg taaatactcc acccattgtt tcgataccaa gtgacaatgg
    12541 cgttacatca agaaggacaa cgtccttgac atcaccagta atcacaccac cttggatagc
    12601 cgcacccata gcaactactt catcagggtt tactgatttg tttggttctt taccagtttc
    12661 agctttaaca gcttcaacaa cggcagggat acgagttgaa ccaccaacaa ggataacttc
    12721 gtcgatttct gacaagctca aacctgcatc tgaaagggct tgacgaactg gaacttttgt
    12781 acgttcaaca aggtcacgag tcaaatcgtc aaatttcgca cgagtcaaag tcatttccaa
    12841 gtgaagaggt ccagcttcac ctgcagtgat aaatggcaag ctgatttgtg ttgaagttac
    12901 accagaaagg tctttcttcg ctttttcagc cgcatctttc aaacgttgca ttgccatctt
    12961 gtcagtagac aagtcgatac cgttttcttt cttgaattct gctaccaagt ggtcaatgat
    13021 tttttggtca aagtcgtcac caccaagttt gttgtcccct gcagttgaca atacgtcgaa
    13081 gacaccgtca cccaattcaa ggatagagac gtcgaatgta ccaccaccaa ggtcaaatac
    13141 caagattttt tcttctttgt cagtcttgtc caaaccataa gcaagagctg ctgcagttgg
    13201 ttcgttaaca atacgttcta cttcaagacc agcaatttta ccagcgtctt ttgttgcttg
    13261 acgttgagcg tcgttgaagt aagccggaac tgtgataaca gctttggtta ctttctcacc
    13321 aaggtagtct tcagcgtagc ctttcaagta ttgaaggatc atagctgaga tttcttgtgg
    13381 agtgtattct tttccatttg cagaaacttt ttcagaagtt cccatcttag atttgataga
    13441 gataactgta tctgggtttg tgactgcttg acgttttgca gcatcaccaa cgatgatttc
    13501 tccgtttttg aatgagacta cagatggagt tgtgcggttt ccttctgggt ttgcgatgat
    13561 tttgctttca gttccttcaa gaactgcaac tgctgagttt gttgtaccta agtcaatacc
    13621 gataatttta gacatgtgtt tttctccttg ttagttaatt ttctattttt ctttttgata
    13681 ctcttcttaa gtggcgacgc cgtcagagct tgacttcgtc agtctctttg actaaacttt
    13741 gagcctaagg tctcaaaatt tgcgcaaata gcgccacggc gaagagtatc gtctttggtt
    13801 cgcttcgctc actattacaa agcaaaacat attttatctt tcttcatagt ttattgtcgt
    13861 ttcggacaag ttttctatta tgtaaattgc gacacgagga gtcgaaatcg attttatttc
    13921 gacgacgagt tagtaaggaa gctaggcaaa cgccatagca attgccgttt tctgacgagt
    13981 tgctttagct accgtcagaa ttgccgaatc gaacacgccc taagctctga gtaaaaaaga
    14041 tagattttct tgtgttcatc gaacacttcg tcaatctcct atttttactg cgagcttttt
    14101 acgagctttg tatcttagtt atacaccact accattgctg ggcgtaggat gcggtcatgg
    14161 agtttgtagc ctttttgaaa gacttgggcg atggtatcta ctgggtgttc atcgtctgct
    14221 gggagagttt ggatggccat atggtagtta tggtcaaatt cgccatctgc tgcgatttct
    14281 tcaattcctt cttctttcaa agcgtgaatc aagctttctt gcaccatccc caagcccttc
    14341 ttcacatcat ctgtcaaacc ttcaactgca agtgcacgct caaggttgtc aagagatggt
    14401 aagattgctt ttgccaagtc ctggctacga taacgttgca agttttgacg ttcttcattg
    14461 gcacggcgtt ggatattttg catttctgca tgagcgcgaa gatatttgtt ttcgaactca
    14521 tctgcacgtt catttgccaa gtccaactta gacttttcag gagttgtttc ttcagctgtt
    14581 tccacaactt cctcttcttg aacttcttct acttcttcat tttttatatc ttgggccatg
    14641 ttcgcctcct ttaatgattt caatcttaat gtacttcgta atgattactg ctgaggtagc
    14701 ggtaaaaatc tgtcaacttc atagtcaaaa cacggttgac cacattgact tgattgatta
    14761 gctgttggta atccagatta actggaccga taatggctag aattccaact cctcgataag
    14821 gaatgaggaa cttactacta atcaccgcta ggtcagctaa acaggactct tgaccgtctg
    14881 caacacgaac attttgcatc tgatcctcac gcaacccctc acgaatctcc aaggccacct
    14941 tttgcggttg gtcaaagaac tgataggctt ctagattggc aaaattcaag agattgacct
    15001 tgcccgccat cacaatgttt tcgttgaaca tttccttaaa gatgtgttca aagagatcga
    15061 tgacattatc cgttgttgta aagtaacgct ggataatctg cggaatctcc gtccgaatct
    15121 tgtagtgaat atctaaaacg gtgtgaccga ggaaacgttc ctgaatgatg ctcttcagtt
    15181 tcagcaaatc ctcctgcaag aagttccttg gaatcagaaa ctgactagta accgttcgcg
    15241 actcgtctag ggtaaatacc gccaaggctg tatgttgccc caaaacaacg atatcaaagg
    15301 ctgtcaaacg ttgcctgctc ggctcaacat ccagtgccac taccgtacag ccactcaggt
    15361 ctgttagcaa gttagcagcc tcttgcagaa tatcctccaa tttgaagaat tcctgatcaa
    15421 aggctttgac aatctcatat acctcatttt cagccagccg gtgaaaatcc agtgagtgtt
    15481 tcacatagta ctgaaaacca gcaacacttg gcatccgacc gcttgaagta tgagccttct
    15541 caagcaaccc ttgtttttct agttccgcca tgtcattacg aatggttgca ctgctagagt
    15601 taatagactc ttgcaaggct tttgatccga caggttcgtg cgttttggta aagatgtcaa
    15661 taatcagatt taaaatatcc tgctgacgct ctgtaaccat ctcatcactc ctctctgtct
    15721 gatcaattag cactcaatgc atccaagtgc taacttatga ttctattata cacccttaaa
    15781 agagaatgtc aagacaaaaa ctcaaaaaat tagcactctt ttatcaagag tgctaaaaat
    15841 caatctgaag acctagaacc ttgctattca tctactcggt atttcctttt tagtctgaaa
    15901 taaccatgaa ttagataaga aatcagaaaa gcatataaaa caaaaataag aaagaaagac
    15961 atagaaagat cctctctaaa caaactcgta caaacaacaa gaccacctaa gaaagtagtt
    16021 gtacaggaac gaagtctaga tcgcataact tcccatttga gccccttact catatagact
    16081 tgatcctctg gaagtaaatc agaagacgat ttacgaagaa tcgaacaaga acctgctcct
    16141 atcaattccc aacctctatc tctaaaatct tgcagttcat gcttatattt tttaagaaat
    16201 ctagaatcat agatacggta gatgacatcg tctggttgac attggtcaaa atagaacaaa
    16261 ccaaaacgac tcgttctata cctccaacct ttcaaatgca tctcatgtaa atattcttct
    16321 tacttgtcca aatcaacaat ggtgaaaatc cgaaattcta ctctgctatt cattgtctta
    16381 ccccaaaatt agaaaacatg cctggcgtta tttattagat aattctttcc acttttgact
    16441 caatctccaa aaaatataag aaatctgaat cgcaaaaact atcaataaaa cccaatctat
    16501 tatgaaaatc aaaaacactt tccaactgaa agaactacct ccagtgacaa actttgagaa
    16561 aaacggtagt agagctaaaa agagaagtaa aataggaagc atccgcattg ttaaaatccg
    16621 tttggcataa aaaaatcttt atttaaacta aaatattata gcaaaattta cgccagtttt
    16681 tgaacggctg atgtagatat tttatacttt caaaatgttt aaatgtgatt atttattttt
    16741 gaaaaatagc tcaccagccc gactgaaagt gcttatagaa tgataataag tcgcctgccg
    16801 aaaacagcga aaaatagcgg tgttatgcgg agataatctg acgcgatgcg aaagtatatt
    16861 gcatacttat tttcaacaat ttagcagagt atttttataa gtgtgatata atagaagtat
    16921 aatttgttct gatagtttat tttatggaga agtagatttt tagaatgcgg agggttcaat
    16981 atggttgagt ttataaagtc taagaaagaa atgagtgagg aggatattaa agcaaatttc
    17041 atcactcctg ctattgtatc caaaggatga aaaaatggtg agcatatcgc ttacgaagaa
    17101 tacttcactg atggtcgaat tgaagttaga ggagataagg ctcgtcgtaa agaaggaaaa
    17161 aaatcagact attcactgta ttaccaattt ggaactcgaa ttgcaattgt tgaggcaaag
    17221 gataataaac acagcgttcg agcaggatta caacaagcta ttgaatatgg agagatttta
    17281 gatgttccat ttgtttattc ttcgaatggt gatggcttta ttgaacacga ccgtatcacg
    17341 agagaagaac gtgagctgga gttagacgaa ttccctactc gtgaagaatt attttctcgt
    17401 atgacgaagg aaaaaggatt gacgtacgaa attacagaag ctatctcaac tccatactat
    17461 acagacgcct tctcaatgaa aacgccacgc tattatcagc aaatagctat caaccgtact
    17521 attgaaacag ttgccagagg acaaaaacga gtaatgtttg tgatggcaac aggaacgggg
    17581 aaaacgttca tggcttttca aattattcat cgccttcgaa aagctggttt ggctaaacga
    17641 gttttattct tagcagatag aaacatctta gtagaccaaa cgatggctga agactttagg
    17701 ccattcgaaa aggtaatgac gaaaattaca ccaaaacttt tgactgctcc tgaaaaatta
    17761 aattcttttg aaatttatct agggctttat cagcaactaa ctggtgaaga tggaactgaa
    17821 acacattatc aaaaatttga caaagacttc tttgatttaa tcgtaattga tgaagcgcac
    17881 cgtggttcag ctaaggaaaa cagtaactgg cgtaaggtaa ttgattattt cagttctgcg
    17941 acacagattg ggatgaccgc tactcctaaa gaaaccaaga atgcttccaa tatggaatac
    18001 tttggtgagc caatctatac ttatagttta aaacagggaa tcgaggatgg ttttttggct
    18061 ccatatcgtg ttatgagggt taatttagat gtggatgtgg gtggttatcg tccagaaact
    18121 ggaaaagttg atgctaacgg acaattaata gaagataggt actacggcag gaaagatttt
    18181 gataaaacca ttgtcattga tgatagaacg caaagagttg ccaagtttgt ttctgattat
    18241 atgaagcaaa acaatgcacg atttgataaa acaattgttt tttgtgttga tattgaccat
    18301 gccgagcgaa tgcgtgctgc acttgtaaaa gagaatctag acttagtcca agaagactat
    18361 cgttatgtca tgcaagtaac tggtgacaac gctgaaggaa aagctcaact ggataacttt
    18421 atggatgtca attctaattt tcccgctatt gtaacaacgt ctaaattatt aacgacagga
    18481 gttaatgcta aaacatgtcg tttgattgtt ttagactcta atatccaatc catgactgaa
    18541 tttaaacaaa ttattggtcg tggcacacgt ctttatcctc aaaaggggaa agaatttttt
    18601 acgattattg attttcgaaa tgttaccaat ttgtttgctg accctgattt tgatggtgat
    18661 ccagtgaagg tgctggaaac aggtgcgaaa acagtcagtg gttctacgcc cggtttcgta
    18721 gatgaggaag gtgacccagt agaaaaatat atcgttacag acaagcaggt taccattctt
    18781 aattctactg ttcaagtatt ggatgaaaac gggaaactga ttaccgaaag cctgaccgac
    18841 tacactcgaa agaatatctt aggtagctac gccactttga acgattttat cacagtttgg
    18901 catacggcag ataagaagaa gcttatctta gacgaacttt ataaaaaagg agtttatcta
    18961 gatgctattc gagagtcgga gggaatatca gaacaagaaa tcgatgattt tgatttactc
    19021 ctaaaacttg cctatggtca aaaagaatta accaaaacgg aacgtatcaa taaactcaaa
    19081 caaagcggat atttatataa atatagtgag gaagcgcgtg ctgttttgga aattttactg
    19141 aacaaataca tggataaagg tattggagaa ctcgaaagca ttgaaacatt aaaacttcca
    19201 gaatttcaga tatatggtgg aaccttcaaa atcatcaata cttattttgg agataaaaaa
    19261 cgatatttac aagcaattaa agaattggag caagagctat ttacagtagc ttaatgaaag
    19321 gaaagtatgt caattacatc atttgtaaaa agaattcaag atatcactcg aaacgatgct
    19381 ggtgttaatg gtgatgctca acgtattgag caaatgtctt ggttattatt cttaaaaatt
    19441 tatgatagcc gtgaaatggt ttgggaatta gaagaagacg agtatgagtc aattatccca
    19501 gaggaattaa aatggcgaaa ttgggctcat gctcaaaatg gggaacgggt attgacaggc
    19561 gatgaattac ttgattttgt caataacaag ttattcaaag agttgaaaga gcttgaaata
    19621 acttcaatta tgcctattcg aaaaacgatt gttaaatcag cttttgaaga tgcgaacaac
    19681 tatatgaaaa atggcgtctt gttacgccaa gtcatcaatg ttattgatga agttgatttc
    19741 aatagccctg aagatcgtca ttcgtttaat gatatttacg aaaaaattct taaagatatt
    19801 caaaatgctg ggaactcagg agaattttat acgccacgtg cagcgactga ttttattgcc
    19861 gaagttctta acccaaaact tggagaatca atggcagacc ttgcttgcgg aacaggaggc
    19921 ttcttgactt cgactctgaa ccgtttaagt agtcaacgta aaactagtga agataccaaa
    19981 aaatataata cagctgtttt tggtattgaa aagaaagcat ttcctcatct tttagcagtt
    20041 acaaatctgt ttcttcacga aattgatgac cctaaaattg ttcatggaaa tactttggag
    20101 aaaaatgttc gtgaatatac ggatgatgaa aaatttgaca ttattatgat gaatccacct
    20161 tttggagggt cagaattaga aacaataaaa aataactttc cagcagaatt acggagttct
    20221 gaaacagctg atttatttat ggctgtcatt atgtatcgtt tgaaagaaaa tggtcgtgtt
    20281 ggagttattt tacctgatgg ttttctattt ggtgaaggtg taaaaactcg cttgaaacaa
    20341 aaactggtag atgagttcaa cttgcatacg attattaggt tgcctcatag tgtctttgca
    20401 ccgtatacag gaatccatac gaacattctt ttctttgata aaacaaagaa aacagaagaa
    20461 acttggtttt atcgtttaga tatgccagat ggttataaaa atttctcgaa aactaagccg
    20521 atgaagtcag aacacttcaa tcctgttcgt gactggtggg aaaatcgtga agagattctg
    20581 gaaggtaagt tctacaaatc taaatcattt acacctagtg aattggctga gttgaattat
    20641 aatttagacc agtgtggttt tccaaaagag gaagaggaaa tcttaaatcc ctttgagttg
    20701 attcagaatt atcaagcgga aagagcaact ttaaatcata agattgataa tgtattagct
    20761 gatattttgc agttgttgga ggacaaataa tgacaccaga acaacttaaa gcaagtattc
    20821 tccaaagagc gatggaaggg aaattagtgc cgcaaaatcc caatgacgaa cctgcaagtg
    20881 aattattaaa gagaattaaa gctgaaaaag aaaaacttat cagtgaagga aaaatcaaac
    20941 gagataaaaa agaaactgag atatttcgtg gtgatgatgg gaaacattat gggaagtttg
    21001 ctgatggaag cactcaagaa attgatgttc cttatgatat tcctgatact tgggagtggg
    21061 tgaggataaa atcaatttat tggaattttg ggcaaaataa gccagagaaa tcctttaggt
    21121 atatagatac gtctagtatt gatagaaaaa agaacataat caactacaaa aatctacaat
    21181 atctttcacc tgaacaagcg ccttcccgtg ctagaaaatt agtttcgcag aatagtgtct
    21241 tattttcaac agttagacca tatctaaaaa atattgctgt agttagagaa cttaaagagt
    21301 atttgatagc tagtacagca tttattgttt tggatacttt acttaacgaa acatatttga
    21361 aatattattt attatcagat aattt
//
LOCUS       DAVLDI010000040        20292 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLDI010000040 DAVLDI010000000
VERSION     DAVLDI010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.040"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..152
                     /locus_tag="VXD01_001524"
     CDS             <1..152
                     /locus_tag="VXD01_001524"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601895.1"
                     /translation="FEVVDETDEVSSKHGFEVADETDEVSSKHGFEVADRTDEVSNIY
                     TVRRR"
     gene            complement(188..1129)
                     /locus_tag="VXD01_001525"
     CDS             complement(188..1129)
                     /locus_tag="VXD01_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV0601896.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(1107..2870)
                     /gene="aspS"
                     /locus_tag="VXD01_001526"
     CDS             complement(1107..2870)
                     /gene="aspS"
                     /locus_tag="VXD01_001526"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV0601897.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            complement(3102..3179)
                     /locus_tag="VXD01_001527"
                     /pseudo
     CDS             complement(3102..3179)
                     /locus_tag="VXD01_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3221..3451)
                     /locus_tag="VXD01_001528"
     CDS             complement(3221..3451)
                     /locus_tag="VXD01_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601898.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(3469..4110)
                     /locus_tag="VXD01_001529"
     CDS             complement(3469..4110)
                     /locus_tag="VXD01_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0601899.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYVSRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(4122..4802)
                     /locus_tag="VXD01_001530"
     CDS             complement(4122..4802)
                     /locus_tag="VXD01_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV0601900.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVAIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            complement(4861..5058)
                     /locus_tag="VXD01_001531"
     CDS             complement(4861..5058)
                     /locus_tag="VXD01_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601901.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(5058..5264)
                     /locus_tag="VXD01_001532"
     CDS             complement(5058..5264)
                     /locus_tag="VXD01_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0601902.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(5274..5588)
                     /locus_tag="VXD01_001533"
     CDS             complement(5274..5588)
                     /locus_tag="VXD01_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601903.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(5741..5914)
                     /locus_tag="VXD01_001534"
     CDS             complement(5741..5914)
                     /locus_tag="VXD01_001534"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601904.1"
                     /translation="MDRTDEVSSKHGFEVVDETDEVSSKYCFEVVDRTDEVSNHTYGK
                     VKLTWFEEIFEEY"
     gene            complement(5903..5983)
                     /locus_tag="VXD01_001535"
                     /pseudo
     CDS             complement(5903..5983)
                     /locus_tag="VXD01_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(5974..7263)
                     /locus_tag="VXD01_001536"
     CDS             complement(5974..7263)
                     /locus_tag="VXD01_001536"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV0601905.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKEA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVSYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(7341..8588)
                     /locus_tag="VXD01_001537"
     CDS             complement(7341..8588)
                     /locus_tag="VXD01_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV0601906.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMLLPTLFTVFAGIRADYTRAKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(8779..9630)
                     /gene="rgg"
                     /locus_tag="VXD01_001538"
     CDS             complement(8779..9630)
                     /gene="rgg"
                     /locus_tag="VXD01_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV0601907.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATRGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEELLFLARGFQYDTDSELRKEITDVLKPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVCIFEMLGCNKSAEY
                     YRNTTEC"
     gene            9754..10095
                     /locus_tag="VXD01_001539"
     CDS             9754..10095
                     /locus_tag="VXD01_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV0601908.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            10153..10233
                     /locus_tag="VXD01_001540"
                     /pseudo
     CDS             10153..10233
                     /locus_tag="VXD01_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10348..12051)
                     /gene="ilvD"
                     /locus_tag="VXD01_001541"
     CDS             complement(10348..12051)
                     /gene="ilvD"
                     /locus_tag="VXD01_001541"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV0601909.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(12284..13216)
                     /locus_tag="VXD01_001542"
     CDS             complement(12284..13216)
                     /locus_tag="VXD01_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV0601910.1"
                     /translation="MMRSTKELQHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(13213..14070)
                     /locus_tag="VXD01_001543"
     CDS             complement(13213..14070)
                     /locus_tag="VXD01_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV0601911.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRIKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(14074..15420)
                     /locus_tag="VXD01_001544"
     CDS             complement(14074..15420)
                     /locus_tag="VXD01_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0601912.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFITKPSAKEE"
     gene            complement(15433..15717)
                     /locus_tag="VXD01_001545"
     CDS             complement(15433..15717)
                     /locus_tag="VXD01_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0601913.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(15721..17751)
                     /locus_tag="VXD01_001546"
     CDS             complement(15721..17751)
                     /locus_tag="VXD01_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV0601914.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            17942..18949
                     /locus_tag="VXD01_001547"
     CDS             17942..18949
                     /locus_tag="VXD01_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV0601915.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            18952..19152
                     /locus_tag="VXD01_001548"
     CDS             18952..19152
                     /locus_tag="VXD01_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV0601916.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            19304..19486
                     /gene="rpmF"
                     /locus_tag="VXD01_001549"
     CDS             19304..19486
                     /gene="rpmF"
                     /locus_tag="VXD01_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV0601917.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            19502..19651
                     /gene="rpmG"
                     /locus_tag="VXD01_001550"
     CDS             19502..19651
                     /gene="rpmG"
                     /locus_tag="VXD01_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0601918.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(20130..>20292)
                     /locus_tag="VXD01_001551"
     CDS             complement(20130..>20292)
                     /locus_tag="VXD01_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV0601919.1"
                     /translation="KGLWYYLNESGSMATGWFTVSGQWYYTYNSGDLLVNTTTPDGYR
                     VNANGEWVG"
BASE COUNT         6487 a         4339 c         3556 g         5910 t
ORIGIN      
        1 gttttgaggt tgtagatgaa actgacgaag tcagctcaaa acatggtttt gaggttgcag
       61 atgaaactga cgaagtcagc tcaaaacatg gttttgaggt tgcagataga actgacgaag
      121 tcagtaacat atatacggta aggcgacgct gacgtggttt gaagagattt tcgaagacta
      181 ttaatcacta attatctatc tcaacaaatc ttcctagaat atgaacattt tccgagacag
      241 agacaaagga gcttggatcc acttgtgtca taatctgttt aaattcatta aactctgcac
      301 gtgtaatgac agtgattaaa actgcctttc tctcgtgatt ataggttcct tctgcatcgt
      361 ggatcatggt tgctccgcgg tgcaattttt tatggatttt ttcaattacc ttctctggat
      421 gatttgtcac aatcatggcc tgcatacgct tttgcttagt aaagactgcg tctgtcacac
      481 ggctagagac aaagatggta atcatagaat aaagagcgta tttccaacca aaggtcaaac
      541 ctgctatcag catgatagtt ccatttacca agaaagaaat actaccgaca ttcttacccg
      601 ttttcttacg aatagtcagg ctaacgatat ccgtcccacc actggagata ttgtttcgaa
      661 gagcaaaacc aatccccaaa cccataacaa cacccccaaa aagggaattg ataatgggat
      721 cctccgtcaa ggttgccaca gggacaaact ggataaagaa ggaactcata gataccgtga
      781 taaaggtaaa gacggtgaac ttatggccaa tctgatacca agctaagacc atcaaaggga
      841 agttaatggc gtagaagctt agcgaaatcg gaatatgaaa accaaaccag tgattactca
      901 aggcagagat aatctgtgcc agacctgttg caccactcga atacacatgc cctggttgga
      961 aaaagaaatt aactgctact gctgataaaa aaccatagac cagagaggcc gaaatcttct
     1021 catcatactt ttctcgagag atactttgta agacacgtaa aatttttatc tgataagcaa
     1081 agcggcgcag ataatagcgc caccgcttaa ttcgttttgt ttgtttcatc ttcttctact
     1141 tgtaagctga gttcctctag ttgtttgaga gcgactgttg atggagcttg tgtcattggg
     1201 tcagttgcct tgttgttctt aggaaaggca atgacttcac ggatattttc ttctccagca
     1261 agcaacatga caaaacggtc aagcccgata gccaaaccac cgtgtggtgg gaaaccatag
     1321 tccatggctt caagaaggaa accaaactgg tcattggctt cttcagctga gaaaccaaga
     1381 gccttgaaca tgcgttcttg aaggtctttt tggttgatac gaaggctacc accaccaagc
     1441 tcataaccgt tcaagacgat atcgtaagca atggcacgaa ccttagccaa atcaccttct
     1501 aattcgtgag cagtctcttc ctgtggaagg gtgaaaggat ggtgggcgct catgtagcgg
     1561 ccttcttctt cagaccattc aaacatcggc cagtcaacca cccaaaggaa gttgaactta
     1621 tcattatcaa tcaagccaag ctctttagca atacgtccac gaagggcacc cagtgttgca
     1681 ttagccactt caagcgtatc cgccacaaag agaaccaagt ccttatcttc aagagcaagc
     1741 gctgttgtca attcttcttg gataccagtc aagaacttgg caactggtcc gtttaattct
     1801 ccatcaacca ccttaaccca agcaagacct ttggcaccat actgtttggc tacttccgtc
     1861 atcttgtcga tgtctttacg tgaatagttg tccgcagctc ctttgaccac aatcgctttt
     1921 acagcaggtg cttctgaaaa gactttaaag tctacacctt tgaccacttc tgtcaagtcc
     1981 tgaagcaaca tgtcaaaacg agtatctggc ttgtcagaac cgtaaagagc catagcatca
     2041 tcgtatttca tacgagggaa cggtagcgtt acttcgatgc cttttgtttc cttcatcacg
     2101 cgcgcgatca agccttctgt aatatcttgg atttcttgct cagtaaggaa ggacgtttcc
     2161 aagtcgacct gagtaaattc aggctggcgg tctccacgca agtcctcgtc acggaaacat
     2221 ttaacgattt ggtagtaacg gtcaaaacca gcattcatca agagctgttt cgtgatttgt
     2281 ggactttgag gaagagcgta aaaatgcccc ttattaacac gagacggtac taaataatca
     2341 cgcgcccctt caggcgttga cttagaaagg aatggtgtct ccacgtcgat aaactccaac
     2401 tcatccaaat agttgcggat agagtgggtc accttggcac gaagtttaag attttccaac
     2461 atttctggac gacgaaggtc aaggtaacgg taacgcaaac gtgtatcgtc atttgcctca
     2521 atgccatcct taatctcaaa tggtgttgtc ttagctgtgt taagcacaat aagagctgtc
     2581 acgtttaact caaccgcacc agttggcaac ttatcattgg cttgctcacg cgcagcgacc
     2641 tgaccagtca cctcaataac aaattcgcta cgaaggcttt cagctgttgc cataacctct
     2701 gcagatactt tttcagggtt gataaccaac tgcatgattc cttcacggtc acgaagatcg
     2761 ataaagatca aaccaccaag gtcacgacga cggccaaccc atcctttcaa ggttatttct
     2821 tgtccgatgt gttcctcacg aacacgacca gcatacatac tacgtttcat tatttctctc
     2881 ctcttttatt ctgttactat tttaccataa aagcgcaggc tcttcatgaa aatcatcaga
     2941 aaagtttgcc agtctttaaa agtcaggtga aagccctaaa aattagcgct aatactcttc
     3001 gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtag tacggttact gacttcgtca
     3061 gtttcatcta caacctcaaa accatgtttt gagctgactt cgtcagttct atccacaacc
     3121 tcaaaacagt gttttgagca acctgcggct agcttcctag tttgctcttt gattttcatt
     3181 gagtataata caaaaatccg atgaacttca ccggactctt ttattttgaa tttttgcctg
     3241 ctttacgctt ttcagcgatt tcggctgcct ttcgaggcaa gacaatttcc gttatgtaag
     3301 ccgtcccaaa acgcagtaca cctgcaatag gagcaaagac aactgctaga tagttataga
     3361 agaaatcgcc tttgaaggca taagctagcg ctccaatgat gaaaaataga acgactgcct
     3421 gaatcactgc taataaaatt actcgtttca tgtgacctcc tgactctatt atagcatgag
     3481 aatcatcaaa aagccgacta aattattcaa agcgtgaaga gaaatactgt agaccagacc
     3541 ttttctgcta acgtaagcca aacccaaact aaaaccaagg ctaaaataga caaaaaattg
     3601 ttgcacatca cctggaaaat gaatcaaggc aaatagaaga ctagatacca gaagaaaaat
     3661 cagggttcgt ttactattgt cctgcttagg aaagagatag cgtgctaaca tccctctaaa
     3721 aacaatctct tccgtcaaag gagcaaaaat aaccacagca aagaatgaga aaagtggttg
     3781 agacaaggtc aagtctgtcg ctatttgttg atttactgaa ggatcatctg gcaagaagaa
     3841 ttgaacgacc agagataaga accaaaccaa ggcaggaagc caaataaatc ggttaaagcc
     3901 gctcttctca atataaacag gagctttctg ataccatttg taaatgccgt acacatatac
     3961 tccagccaag accacataga gtagagtaac agcatagggt gaagcgccta aagcaagcga
     4021 cgcagtcgcg agcccctgaa taaagccata gataaagaaa aaggatagaa gggctagaag
     4081 aaaccagcca agatttttaa gtaatttcat agataactcc tttatttgaa ataacgtttt
     4141 accataggta actgcatcac attgatataa acatggatgg ctcctacaag caagaaagct
     4201 agtaactgaa tctctcctgt caagaaagaa aggataataa gaaaaatata taaggctggt
     4261 aagacatatt ggtgtaattg gaataaaatt cgaaaactct gttccaaatt agcctgacgc
     4321 tccccttcat cataagaatt tatatagttc aagacatcct ttggtgtagc gaaaaattcc
     4381 aaatcaaact gacgaacaat cgcaatggtt ttaaaaagag atttttgagc gactaagaat
     4441 accacaaaga gtaagaaaga aaggaaaaat gtttgagggt ttgtatgcaa tataatcacc
     4501 tcacttaatg aaataaaaat agccaatgga atcgctacac ctgtaatatt aaaagcaatg
     4561 gttccaaact caagattccg atacatttgc acataatagg tttcattcag atcgtcatcc
     4621 atttcctctt gatacaagga atgaaatttt ctgcttttct ttaagaaatt gaaagtcaaa
     4681 aacatactaa tgaaacctat cagtaaacaa atagctgata tccatggcat caaggctttt
     4741 acatctaaaa taatttcgtg ggattcgaca cgtgccttaa acatccctac aaacatgccc
     4801 aagacccccc cccaaagaca atagacatca aaaataacaa tctacgtttc tttttcatat
     4861 tcattctcct ttttcacttg ctagattttt ggatttcttt tcaatccatt caattactgg
     4921 gatgagagca aagtagaccc aaacaaattg gtcgctttga tagggattaa accagcttag
     4981 gtccatccca atcagtagaa atacgctgac taataaagct atgaccacta cataataaat
     5041 cactttatac ttgttcatca ctcgtcctcc tccaaacgaa ataccgattc gactgtttcg
     5101 ttgaaaattt gagatatttt cagggcaatg ataatggatg gggtgtactc atcccgttct
     5161 agtaggctaa tggtctgtct ggaaacccct gccagtttgg ctaggtcggt ttgattgaga
     5221 ccatcgcgag ctcgaagctc ttttagacga ttttttagtt gcacgttaca cacctactct
     5281 ccgtcaaatt caacggtttg gatatcttca atacgttgca acttgaattt ttcttttccc
     5341 gtattatcaa cactacgtag tttgacccat tcctcatcaa catccacaac ttcccagtta
     5401 tctggcccaa tatacactcc cgttataatt ggttcctttc caatcatttc ttgtaataat
     5461 ctcgacattt ctgcgtttcc tttctctttt cgctcaagtt ttttgatttt attctctagt
     5521 ttcttgattt ttttagaatt attagaataa aagaaaatca taaatagtat aaatcctagt
     5581 acccacatta taactccttt ctgcttccta tttcttaact tgaattcatt gtaacatatc
     5641 tttttctttt tgacaagtat atttgtcaaa aagtttatga tttttgtcat tttgcaaaag
     5701 aaaaaggtca ggagtaagtt cctgaccact ttatctatca ttaatactct tcgaaaatct
     5761 cttcaaacca cgtcagcttc accttgccgt aggtatggtt actgacttcg tcagttctat
     5821 ctacaacctc aaaacagtat tttgagctga cttcgtcagt ttcatctaca acctcaaaac
     5881 catgttttga gctgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagcaac
     5941 ctgcggctag cttcctagtt tgctctttga tttttattga gtataaaatc ctagtttttc
     6001 aaagatttct gagaagtttt ggctgattgt ctcaagtgac acttgcactt cttctcgagt
     6061 ttggttgttc ttgaccgtca cttgtccgct ttcgacttcg ctctctccta gggtgatgag
     6121 ggtcttagcc acaaagacat cggctgactt gaactgagct tttagtttac ggttgaggta
     6181 atcacgctct gctttgaaac cttgttggcg aagagcctgt actaattcca aggccttgat
     6241 atttgcccct tcgcccaaga ctgcgatata gacatctagg gcgttttcga tagggagggt
     6301 cacaccttgc ttttcaagaa tgagaagcag gcgctctaca ccaagtccaa aaccaaatcc
     6361 agcagtttca gggcctccaa aataagaaac caaaccatcg taacgaccac ccgcacagac
     6421 ggtcaggtca ttgccctcaa tctctgtgat aaactcgaaa atggtgtggt tgtagtagtc
     6481 cagaccacgc accatattgg tatcgatgat gtaatctact ccaagatttt ccaacatctg
     6541 acgcacagca tcaaaatgag cttggctttc ttcatcaaga aagtccaaga tagacggcgc
     6601 attctctact gcctccttgt cttctttttc cttagagtcc aagacacgaa gaggattttc
     6661 ctccaagcga cgttggctat ccttagacaa ggtctccttg agcggtgtca aatagtcaat
     6721 caaggcttgg cggtaggctg cacggctctc aggatttcca agagtgttga ggtgcaattt
     6781 gacaccttga ataccgattt ccttcaaaaa atgggctgcc atagcgattg tttccacatc
     6841 ggtagctgga ttgctagagc caaaacactc aacaccaatt tggtggaatt ggcgcaagcg
     6901 ccctgcctgt ggacgctcat aacggaacat aggtcccata tagtagaact tgcttggctt
     6961 ttgcacttct ggggcgaaga gtttattttc cacataggaa cggacaacgg gcgcagttcc
     7021 ttctggacgg agggtaatat gacggtcacc cttgtcataa aaatcgtaca tttccttggt
     7081 tacgatatcc gttgtatctc cgacagagcg actgataacc tcgtaatgct caaaaatagg
     7141 cgtgcgcact tctgcatagt tatagcgctt gaaaatctca cgggcaaagc cctcaacgta
     7201 ctgccactta gcagattcag caggtaaaat atcctgcgtt ccttttggtt tttgtaattt
     7261 catagggaat cctctttaaa cttaatagtc ttattttacc acaaataaag ggattaaaac
     7321 agtaagaaaa aaattaggat ttagatatca tttttgagat taagaattgt caaaaaaata
     7381 gctagcaagg aaagaccaac aaatagcatc caagtcaact gtatattcca tacggctact
     7441 agtgaaaaac aagctgttcc cacaggtatg gataaggtaa acaatagacc taaaaaatta
     7501 ctagtacgag ctagaacctc tggagctaga tttttcatga gcatggcact aatctttggt
     7561 tgaactttac cagacacata cagggtaaag aagagaaata gcaaaccaag cacgacttga
     7621 ttgaataaat tagccaaacc aactagacta agtcctacgg tcgcccacat catcaatcta
     7681 ggcaaggact gcttcccaaa ataatcattg cccgtaaggc tactgatgat gattgctact
     7741 aaaacacaga attgattgat aaatagtgcc tctgtataag aaaaattcaa gagagaatgg
     7801 ctcaaaaaga agatattata aattccaccc aaagcgccac ccaaggaatt aataagcaag
     7861 acagcaaaga gcataaaacc aaagtttttc tgtccacttt taagaaaaac gagacgtaaa
     7921 tttcggtaaa ttgttaggaa ctggtctttg atagaaagct tctcattttt taagttttca
     7981 ccatcagcag atgacattga caggctcaat ttgctttttc ctaaaaagag gatagtggct
     8041 gatactagga aaaagcaggc attgattccc gcaacgagag aaaaattgtt gaccgataga
     8101 gctaagagcc agactccgaa agcttgacca ccaatagctg aaatataggt gatgaactgt
     8161 gaaaaagaat aagcctccat caaatcatct tcagctactt tttccttaat aagaggcata
     8221 cgcaggccac ctgcaaaatc actgatgata tcactaatga cattgatcaa acacaggcta
     8281 gaaaaggcaa ataaactagc ttgctgaaca actagggctg ccagaaaaaa taaaaccgcc
     8341 tgaaacaaac cgctatagac catccatttg accttggccc tcgtgtaatc tgcccgaatc
     8401 cctgcaaaaa ctgtaaagag agtcggaaga agcatgacaa tattcgccat agcaacagca
     8461 aaagatgctt gtgacaaggt cgatgcatag acgataaaga ccagattgaa aatcgaagca
     8521 ccaaaagcat tgaagaagcg tgataaagtc aaaattctat aagctggatt tctaaacaat
     8581 agtttcatag ataatctccc tccttgttct aagttctaca tcaagaatag ctttagtata
     8641 gcacttatga atttgcgaaa cgattctttt gaatatatgc aacaaataaa atgagcaaaa
     8701 aaacgataga acttttgtaa tgacctgaga gagggcaata gttctatcgc ttcaaatttt
     8761 ttcttggttt gcagatattc aacattcggt cgtatttcta tagtattcgg cagatttatt
     8821 acagccaagc atctcaaaaa tacagacagc atcctccatc tttttctggc cttccttgac
     8881 tctaccttgc ttgctatcaa ggagaccttc tgcccacaga taaacaattc ggaaataggt
     8941 ctcattttcc ttgtagaaat gctcttcgat aacacgttta aaataatagg cattggtaaa
     9001 ttcttcacac tcaatactag ctaaaaagcc attcaatagt atagtatgaa aaaggtttcg
     9061 attgccagac atttccatta gaaaatcaga tttacgtacc atttctcgta catatctagt
     9121 aaaaagagaa acagataaaa atggagaact gactgaaaat aaattgagtt catagattcc
     9181 ccagatctcg gtagaaaaca aataatcatg aaggactttt ccttcctctg ctgttaagtc
     9241 taccctttca tctatgctct tcatataaga cttgataata atggcattta gaatatgttt
     9301 ctgtttgttg tgagaatggg catgcttttg atactccctg cgatataagt cctcaagagg
     9361 tgctatattc tttggtttca agacatctgt aatttctttt ctcaactcag aatctgtatc
     9421 atactggaaa cctctcgcca gaaagaggag ctcctccaca ctggcagata tattttccag
     9481 agcaaataga aacttttcca ccgaaagctc actctgacct gtttcaaaac gggacaacat
     9541 agacggcgaa aattgtcctc tggttgcttg tctcagtgag atatttcttg actctcgtaa
     9601 ttgtctaaag acttttccaa tctgctccat agacttcccc ttgattccgt attttcttca
     9661 ttttatcata tttttcagaa aattcatcaa aaacttgcca aattgtcaga attatgagaa
     9721 aatagaggat atttatcacg tggagggact gctatgagag acgatatcaa aatcaatgac
     9781 cgtgctttgg ccttgcaaga ccaaattatc gaaaaactag agaaagtttt tgatacagat
     9841 gtggaattgg atgtttacaa tctaggtctg atttatgaaa tcaatctgga tgaaacgggg
     9901 ctctgcaaga ttgtcatgac cttcaccgat actgcctgtg attgcgccga aagcctgcct
     9961 attgaaatcg tggcaggtct gaaacaaatc gagggtatca aagatatcaa ggttgaagtt
    10021 acctggtcgc ctgcttggaa aatcacacga atcagtcgct atggccgtat tgcccttgga
    10081 ctaccacctc gttaagcagg ccaatcactt ttaaagatga aaaaagcaag ccgaaaatgg
    10141 cttgcttttt gatactcaat gaaaatcaaa gggcaaacta gaaaactagc cgcaggttgc
    10201 tcaaaacact gttttgaagt tgtggataga actgacgaag tcagctcaaa acatggtttt
    10261 gaggttgtag atgaaactga cgaagtcagt aaccgtacta cggcaaggcg acgttgacgt
    10321 gatttgaaga gattttcgag tatgagttta ttttttacct gacttgtcca tattccagaa
    10381 gtctgtcacg gctccgcgtg aagcagatga tacgatgtgg gcatatttac cgaggacacc
    10441 acggctgtaa agtggtggca aggttgtttc tgccttgcgt ttttcaagtt cttcttcgga
    10501 tacggccatg gaaatttctt tggtatcttg gtcaaccgta acgatatcgc cggtacggag
    10561 ataggcaatt ggtccaccat cctgagcttc aggagcgata tgtccaacaa ccagaccata
    10621 agtaccacca gagaaacgtc cgtccgtcaa gagggccacc ttatctccct gacctttacc
    10681 aacaatcatt gaagaaagtg acagcatctc aggcatacca ggaccacctt taggtccaac
    10741 aaaacgaaca acgactacat cgccatcaac gatttcatct gtcagaacgg cctgaatcgc
    10801 atcttcttct gagtcaaaga ccttagctgg cccaacgtga cgacgcactt taacacctga
    10861 taccttggca actgcaccgt caggagcaag gttcccgttc aagatgataa gcggaccatc
    10921 cgcacgtttt ggattttcaa gtggcatgat aactttttgg cctggagtca agtctgcaaa
    10981 gtcagccaag ttttcagcta cagtcttacc agtacatgtg atgcgatctc cgtgaaggaa
    11041 accatttgcc aacaagtact tcataaccgc agggacacca ccgacttcgt agaggtcttg
    11101 gaagacatac tgaccagatg gtttcaagtc ggccaagtga ggcacacgtt cttgaatcgt
    11161 attgaagtcc tcaagtgaca agtcaacatt tgcggcatgg gcaatggcga gcaagtgaag
    11221 agtggcgttt gtagaaccac cgagagccat cgttacagta atagcatctt caaaggcttc
    11281 acgagtcaag atatctgatg gtttgagacc aagttccaac atcttaacaa cagcacgtcc
    11341 tgctgcttcg atatcttctt tcttatcagc tgattcagct gggtgagagg atgaccctgg
    11401 caaactcatc cctagaactt cgatagcagt tgccatggta ttagcagtat acataccacc
    11461 acaaccacca gggccagggc aggcattaca ttcaagacgt ttcacgtcct cagctgtcat
    11521 gtcaccgtgg ttccattttc cgataccttc aaagacagaa accaagtcga tatctttacc
    11581 atcaagattt cccggtgcaa tagttccacc ataggcgaaa atagctggga tatccatatt
    11641 agcaatagca atcatagatc caggcatgtt cttgtcacag ccaccgatag cgacgaaggc
    11701 atccacgttg tgaccactca tagccgcctc gatggagtcc gcgatgatgt cacgagatgt
    11761 tagagagaaa cgcataccag gcgttcccat agcgatcccg tccgctacgg taatggttcc
    11821 aaactgtaca ggccaagcgc ctgcagattt gacaccttct ttagccagtt tcccgaaatc
    11881 atgcaagtga atgttacatg gtgtattttc cgcccaagtc gaaatcactc ccacaatcga
    11941 tgtttcaaag tccttatctg tcataccagt cgcacgaagc atagcacggt taggtgattt
    12001 aaccatgctg tcatagatgc tactgcggtg acgtttatct aattcagtca tcttatccct
    12061 cccatttcag tttttactat tatagcacaa tttaaaggca atgaacagaa taaaattctt
    12121 gaattttcag aaaattctat acgcatgtga aatatttaaa attaaaaaca acaaagcgga
    12181 ttagtgcact ttctgatgac cagaatatgc tttttaatcc gctttcttta aataacgtaa
    12241 tgtaattttt acagaaattc tttcagataa gtgtatttaa catctatctt gcattataaa
    12301 tttctagaac cttctctttt atattcgatt cactcaaacc atactcatta agaagataat
    12361 ccattttccc tacttgacca aatctttctt gaacacccat ccgatgaatt tttgttattc
    12421 catcatcaga gaataattca cataaagcac tgccaattcc acctatctga ttgtggtttt
    12481 ctacagtaaa tatagttttt ccacttaaca ttgtttttat ctgttctggt atcggtttga
    12541 ttctaaataa atctatcaca cctactgaat aacctaattt agacagttca tctgcaactc
    12601 gaatacttgg agcaaccatt ataccagaag caacgattac aagatcttca ccatgcctta
    12661 actcaatgta gcctttagaa aaatcttctc caccttgata cacaggaact ggagcttttc
    12721 taattgttcg aatatatttt agtcctttta agtctaatgt ctggttcaat atttcacgaa
    12781 attggatatc atcagttgct tcaaaaatga tcgatttagg aattaaacgt aacaatccaa
    12841 tttcttcaaa tggcatatgt gtcccaccat tcatttctgc agttactcct gcatctgatc
    12901 caatcacagt ggcatccaat tgtgcgtatc caagagaaat aaataattga tcaaatactc
    12961 ttcgtgaagc aaaaggacca aatgtatgaa gataaggtct aaacccctga atagacaagc
    13021 ctgctgcaag gccgaccatt tctgcttcca taatcccaac attcacataa cggtctccaa
    13081 agtccttttc aagattatga gtagccatcg aacttgacag atcggcttct aagactacta
    13141 tatcagaata actttgatta gcctctaaaa ggaagtctct atatacatgc tgtaattctt
    13201 tcgtacttct catcattctg tttcctccaa ttcctgactt aatctttcta caactgaagt
    13261 taacatttgt ctctcctcta cagtagggcg aagatgatga ttggatttca tttcttccag
    13321 ctcttgaacc ccttgacctt taatagtatc taatacaatg cacttaggtg atgaattatt
    13381 tgactgtttt aattggacaa tcccttcata aatttctcta atatctgaac ccttgatcct
    13441 aatggattca aatccaaatg ctgaaaattt ttctacgaaa tcacctggat tacaaatatc
    13501 ctttgtaaaa ccatctaatt gttttttgtt atcatcaaca aatacaatta agttggataa
    13561 ctgttgatga gaagcaaact gtatagcctc ccaacattgt ccctcattta actcaccatc
    13621 tccaacaata gcataagtat aaaagggact ctttcttatt ctctgaccat atgcaagtcc
    13681 agttgcaaca ctaattcctt gtcctaaaga gcccgttgtc atatctatgc ctggcgttag
    13741 atttctatca ggatgagacg gtaatttggt tccatttgta tttaaagaat ataagaattc
    13801 tttgtcaaag aaaccattca aatagagtgt actgtataga gctggtcctc cgtgaccttt
    13861 tgataatatg aaataatctc tatctcgtgc tgcaaatatt tctggagtca ttggcattat
    13921 ttcaccataa agcactgcta aaacttctac gatagacaga cttcctccgt aatgtccgaa
    13981 tccaagatga ttcaatgttc taagagtatt taatcggatg ttagtcgcaa attttcttaa
    14041 ctcatcttcc ctatttttac ttaaaatcat cccttattcc tcctttgcag atggctttgt
    14101 aataaaggat actccaaaca taactgctag aataagaaca agaccaatca caatgcctgc
    14161 ttgtgagcca aattgattta acattcctaa aataattcct gatagaccaa aatctgcatc
    14221 tgagaaagtt gatccttgga aaccaagtcc tcccaaaact ggcattaaaa agactggaag
    14281 aaaactgatt aaaatacctt gtaaaaatgc tccaatagtg gctccacgaa caccaccaga
    14341 tgcattccca atgacacctg cagtcgctcc acagaagaaa tgaggcacaa cacctggtaa
    14401 gataacaacc gttcctgaag caatcataat tgccatactt actaaaccac caacaaaact
    14461 agagataaat ccaattagaa ctgcattggg tgcataagta taaacaatcg gacaatccaa
    14521 agcaggtttt gaattaggta caagacgctc tgaaatacct ttaaaggctg gaacaatttc
    14581 gcccaaaata aggcgaacac ctgctaaaat aacaaatacc cctgctgcaa attgacctgc
    14641 taattgtaaa gcataaacta gaccacttgt accactactg atttcttttt ctatatattc
    14701 tgaccctgca aagatagcta caataatgta aataactgcc atggataaag tgatactaac
    14761 agtactatca cgtaaaaaag ctaaactctt tggaaattta atgtcctctg ttgattttga
    14821 tttgtcaccg ataaggctac cagtaaaacc actcaaccaa tatcccaaag aactgaaatg
    14881 acctaaagcc accttgtcat ttccagttaa ttgaaccata tatttttgaa caaatgctgg
    14941 ggaaatactc ataataatac cgagtgctaa tcctcctagt aagataagag gcaagctagt
    15001 aaagccagca actgataaaa tgaccgcaat catacatgcc atatatagag tgtggtgccc
    15061 tgttaaaaaa atatatttaa atcgagtaaa acgagcgatt aagatattga acaccatgcc
    15121 tgcaaacata atcagtgcag tagctgagcc atatgttgtt aaagctacag ctacaattgc
    15181 ttcattattc ggcacaacgc cagataaatg aaaagcatgc tcaaacatgg taccaaatgg
    15241 atttaaagaa ttttgtacaa ttcctgcacc accagataca actaagaaac caacaaaggt
    15301 cttaattcca cctttaataa tatcaggtaa tttcttcttc tgaagaacta atcctaaaat
    15361 tgcaattaaa gctactaaaa tagctggtgt actaacaata tccaatatga acttcatcat
    15421 aacgctagcc tcctatataa gtcctttttc ttcacaaagt ttagtaatta attctcgtag
    15481 ttcatccata tcaataatac tatttaagat acgaacatct ccaagatgac tagctgaatc
    15541 agctagatca cgaccaacaa tccaaatatc agctgcattt ggatctgctc cacctaaatc
    15601 ataatgttca acttctacat ccgaaacatt caaatcactc aatacagatt caatattcat
    15661 ctgtaccata aaacttgaac ctaatcctga accacaagct gtaccaattt ttaacattat
    15721 ctaatcctcc tgtttaatta tcattttaat gtcatcatag ttttttgatg atattaaagt
    15781 ttgaacatga tttttatctc ttaaaattgt tgttaaatgt gacaaagcct ttaaatgact
    15841 ctcattatca atggctgcaa tacaaatcaa caatcttacc tcttgttctg gattatccaa
    15901 taaataaatc ggttcttcca aaactaacat tgacattcct atttcattca caccttcatc
    15961 tggccgagcg tgaggaattg ctactccctt ccctaaatta ataaaaggcc caaactcttc
    16021 tactttttga atcattgcct cagggtagtt ctcagttatc ttatcttgat ccaaaagcgg
    16081 tttagctgct aaacgaatcg cctccttcca tcctaatttt tgcgaactaa cctgataggt
    16141 ttctttggta atgagttgtt ctagcactgg tacaatttcc tttctatcat ttttttggta
    16201 aagataattc tttaacgcca atcttaattc caattcttgt gtaataattc catatctttt
    16261 gacaatattc aggatttgtt caatctcaaa atccccatac tctaaattcg gaaaatcttt
    16321 taacactagt tctactagtt gtattgcttg ctcttcagtc atcataaccg aaactagata
    16381 atttggcttt tctgtctcca cctttatggt agaaaaaacc atatcatagt cactactagc
    16441 tttcacctgt aaatcatcaa tctttgaggt tcctataaac tcaatttgag gaaataatgc
    16501 taatagattc tcttttaaca tcaatgaaga actaacacca ttaggacaaa tgattgctgc
    16561 tttatagcat ttttgaggca aagtatctgc tttctttaaa taacctccga aatggataac
    16621 aaaatatgct gtttcactat caggtatggg attgtcaata gcgtccatca agggcatcaa
    16681 agaatctttg actaattcaa ataaatcagg ataatgttct ttaacatgca atacatattc
    16741 atttgaacta ggtaggccga actttaatct atagtaagcc ggtataaggt ggcggcgaag
    16801 attttctctc aatccttccc tttgtttaaa atgtaacaaa gaaatatctt ccattctact
    16861 tataatagcc tctgttaatt gattaaagta aaccggagca acatctactt caccttcaaa
    16921 gcaacttgat aataaaacgg tgatatagcg ataatcatcc tcagaaaaca ccgtatctat
    16981 aattcccaaa tcaaccactg tatccaataa aatagtcgtt atatcttgaa taacaggaga
    17041 tactaatgtc tctgaaagac atactctttc aacatccctt tgatacctac acagaatgaa
    17101 tactaaaccg aaaaggcaaa cttttaattg attaacaata ggtactagct gtagcttctc
    17161 ataataatct ttaactacct gatttatcaa atcataagtt aatgaatacc cccaactgga
    17221 taaaacataa tccaaacccc aaatccctat ggaggattcc agcaactcac taaccatttg
    17281 aaaagctaag cggtgcttat tccactctga accgtgtaaa gtataacctt ttgctctact
    17341 gtaccctagc tccaaatcat tatctaacat aatctttctt aatgattgaa tatcagataa
    17401 ggttgtattc ttacttactt tcaaaaagtc ttggtaatga ttattcgata taaaatctaa
    17461 tcggcaaaaa gtgtaaagat agattaaagc taagcgagtc gactttggta aaaccaattc
    17521 atccgactta ataatatctg tcaaagactg cttcgtacga tttgataaac tatagcgacc
    17581 ttgtttttta tccagcacta tccctttatt agctagataa ggcactaaat aatctattcc
    17641 ttctttgact tcctttatag gtaagctcac cttaacagat aattcatata atgatagctc
    17701 acaatgatcc atcaaagtca tcaaaataac tagtgctcta taatcaaaca tttctcttcc
    17761 tttctaacta caattatagt gtaaaaatta taagaataaa agagtatttg agcacaatat
    17821 aatctcacct tttaaaagaa attattgggc tgaaactttt tagtgattat tttcaacttt
    17881 ctattgactt ttaaaaacaa agtgatatca tttagatatc aaataatagg aggtcattct
    17941 tatgactgaa aaactcatca attcaaaacc aaatggtgta ttcgcattga ttctcattga
    18001 attgacaatc gtacttggta tctttatatt tataatgggt gttggttcgg aaaacatttt
    18061 tggaattatt atcggacctt tactaatcgt aattgcaggt ctagctcatg ctggtttaaa
    18121 agttgtcaaa cctcaggaag ctctggttct gacactcttt ggtaattata caggtaccat
    18181 caaagaacct ggtttttact ttgtcaatcc cttcagcgta gcagtcaacc ctgcaaacca
    18241 cactcgactt ggacaaagtg gtgatgttag cacaaaatct ccttttttag gagctaaatc
    18301 atcaaatgac aatgatgtaa atcttgaaat tggcaagaaa cagatttccc tcaaagtcat
    18361 gaccttgagc aattctcgtc aaaaaatcaa tgattgctta ggaaaccctg tagaaatcgg
    18421 tatcgcggta acttggagag ttgtcgatac cgctaaggca gtcttcaacg ttgataacta
    18481 caaagaatat ctttcattgc aatgtgatag cgccctccgt aatattgtcc gcatctatcc
    18541 ttacgatgtg tctcctaatg tggatactac gggtgacggg caagcagatg aaggtagtct
    18601 ccgtggctct agcgaaattg ttgctaaccg tattcgtgaa gaaatccaaa gtcgtgttga
    18661 ggatgctggc ttggaaatcc ttgaagcacg tatcacttac ctagcttatg ctccagaaat
    18721 tgctgccgtt atgcttcaac gccaacaagc atctgccatt attgatgcac gtaagatgat
    18781 tgtagatggt gctgtaggaa tggttgaaat ggcactagaa cggctcaatg aaggggaatt
    18841 ggtagaactt gacgaagaac gaaaagctgc catggtttca aatctccttg tcgttctttg
    18901 tggcaatcat gatgcacaac caattgtcaa cacaggaagt ctttactaaa gatggctgaa
    18961 gctaaaaaaa agcagatccc ccttcgactc tcaacaaagt tatacgctgc actcgcatca
    19021 tgggcagaag acgactttcg ttcagtcaat gggcaaatag aatatctcct cacagagtgt
    19081 gtcaagcaac ggaaaaaaga cggaaaatac gtatcagaaa ccattgacga accatttgag
    19141 attgatattt aacaccttct cctgtctgcc gtgtcggata ggagaatttt ttcatctttt
    19201 tttgtcaagt aactttactt tacaaaaaaa atgtgttatc ctagtatggt tgatgaaaat
    19261 cagtagattg aatcgaatat aaatacctaa aggagaaatc aaaatggcag tacctgcacg
    19321 tcgcacttca aaagcgaaga aaaacaaacg tcgtacacac tacaaagtaa cagctccatc
    19381 tgtaaacttt gacgaaacta ctggagatta ctcacgttct caccgtgtat cacttaaagg
    19441 atactacaaa ggacgtaaaa tcgctaaagc tgcatcagct gaataataga agggagatac
    19501 tatgcgcgta aatattacac ttgaacacaa agaatctggt gaacgcttgt accttacttc
    19561 taaaaacaaa cgtaacactc cagaccgcct tcaattgaag aaatactcac caaaacttcg
    19621 caaacacgtt gtgtttacag aagtgaagta agcattcaat acgaatcaat acagaagaaa
    19681 aacgcttgat cagcgttttt tctttttgtt aatttcacta tattgcaagg gaaatcattc
    19741 gaatgactac attattgaaa taagaatacg gattcggaca attaaaagca agaggaactc
    19801 aaatgtaagt tggggttcct tttttgtata tttttcaaat aacgcctcta cactatttgt
    19861 agcaaattca ccaactacag ttgtatctta gttaaaataa gttagaatat gtaagtgagt
    19921 accagatata ccaagacatc gtcaccatct aaggtatatt caaaatacaa aagttgacca
    19981 actagatttc tgaatatcct tatatatcca ttcttaaaat tggtttaaat agcgtagtct
    20041 tttaaactag ttttgagaat ccaaaaaatc ttcctacata tgtaagaaga ttttttagtt
    20101 cagaatgatt agatttagct aatggatacc tatcctaccc actcaccgtt agcattgact
    20161 cgatagccat cgggtgtagt cgtgtttact aataaatctc ctgaattata ggtatagtac
    20221 cattgaccag aaactgtaaa ccaaccagta gccattgaac ctgattcatt taagtaatac
    20281 cataagcctt tg
//
LOCUS       DAVLDI010000041        19973 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLDI010000041 DAVLDI010000000
VERSION     DAVLDI010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.041"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            135..1616
                     /locus_tag="VXD01_001552"
     CDS             135..1616
                     /locus_tag="VXD01_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0601920.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            1978..2979
                     /locus_tag="VXD01_001553"
     CDS             1978..2979
                     /locus_tag="VXD01_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0601921.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3128..4045
                     /locus_tag="VXD01_001554"
     CDS             3128..4045
                     /locus_tag="VXD01_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0601922.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4056..4946
                     /locus_tag="VXD01_001555"
     CDS             4056..4946
                     /locus_tag="VXD01_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0601923.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            4975..6591
                     /locus_tag="VXD01_001556"
     CDS             4975..6591
                     /locus_tag="VXD01_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV0601924.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     SDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6601..7920
                     /locus_tag="VXD01_001557"
     CDS             6601..7920
                     /locus_tag="VXD01_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV0601925.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8128..8200)
                     /locus_tag="VXD01_001558"
     tRNA            complement(8128..8200)
                     /locus_tag="VXD01_001558"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8165..8167),aa:Lys,seq:ctt)
     gene            complement(8465..9736)
                     /locus_tag="VXD01_001559"
     CDS             complement(8465..9736)
                     /locus_tag="VXD01_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV0601926.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            10034..10249
                     /locus_tag="VXD01_001560"
     CDS             10034..10249
                     /locus_tag="VXD01_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601927.1"
                     /translation="MMELPSQEILIFTKQIRHWILSDQVISGKRKLFFWEDTPKEILD
                     LYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            10414..10593
                     /locus_tag="VXD01_001561"
     CDS             10414..10593
                     /locus_tag="VXD01_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601928.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10730..10909
                     /locus_tag="VXD01_001562"
     CDS             10730..10909
                     /locus_tag="VXD01_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV0601929.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGK
                     LNKYTERGIRKQAGL"
     gene            10946..11398
                     /locus_tag="VXD01_001563"
     CDS             10946..11398
                     /locus_tag="VXD01_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV0601930.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11689..12159
                     /locus_tag="VXD01_001564"
     CDS             11689..12159
                     /locus_tag="VXD01_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV0601931.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12178..13281
                     /locus_tag="VXD01_001565"
     CDS             12178..13281
                     /locus_tag="VXD01_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV0601932.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERATTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNFWFPRL"
     gene            13247..13675
                     /locus_tag="VXD01_001566"
     CDS             13247..13675
                     /locus_tag="VXD01_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV0601933.1"
                     /translation="MELEISGFPGCKIALFCEDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            13813..14763
                     /locus_tag="VXD01_001567"
     CDS             13813..14763
                     /locus_tag="VXD01_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV0601934.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            14765..15508
                     /locus_tag="VXD01_001568"
     CDS             14765..15508
                     /locus_tag="VXD01_001568"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV0601935.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDFIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            15519..17315
                     /gene="pepF"
                     /locus_tag="VXD01_001569"
     CDS             15519..17315
                     /gene="pepF"
                     /locus_tag="VXD01_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV0601936.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            17562..18353
                     /locus_tag="VXD01_001570"
     CDS             17562..18353
                     /locus_tag="VXD01_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV0601937.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDVGLDKEIDKVGLPTLERSFRALVYANLLYADANQ
                     QSVFYQGLQLEIRNVFSNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFSKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            18464..19132
                     /locus_tag="VXD01_001571"
     CDS             18464..19132
                     /locus_tag="VXD01_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV0601938.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGFDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGPIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(19301..19390)
                     /locus_tag="VXD01_001572"
                     /pseudo
     CDS             complement(19301..19390)
                     /locus_tag="VXD01_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(19387..19713)
                     /gene="queF"
                     /locus_tag="VXD01_001573"
                     /pseudo
     CDS             complement(19387..19713)
                     /gene="queF"
                     /locus_tag="VXD01_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000082574.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
     gene            complement(19708..19857)
                     /locus_tag="VXD01_001574"
                     /pseudo
     CDS             complement(19708..19857)
                     /locus_tag="VXD01_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730462.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase"
BASE COUNT         6094 a         3446 c         4357 g         6076 t
ORIGIN      
        1 atatattgtc tccgtagtgt tattatacga aataaaagat tttaggaaaa gtcgttatat
       61 catgctatac ctattctttg tggtataatt gcaagaggtt taatccgata atttataaag
      121 agagaaagat attcatgaga gatttattat ctaaaaaaag tcataggcaa ttagaattat
      181 tagaattatt atttgaacat aaacgttggt ttcatcgttc tgaactagca gagttattaa
      241 attgtacaga acgtgcagtc aaagatgatc tatcccatgt taaatctgct tttcctgact
      301 tgatttttca ttcttctact aatggtatac gcattattaa taccgatgat agtgatattg
      361 aaatggttta ccatcatttc tttaaacatt caactcattt ttcgatttta gaattcatct
      421 tctttaatga aggttgtcaa gctgagagta tttgtaaaga attttatatc agttcatctt
      481 cgctctatcg tattattagc caaatcaata aagtgattaa aaggcaattt caatttgaag
      541 tcagtctgac ccctgttcaa atcattggaa atgagagaga cattcgttac ttttttgcac
      601 aatatttttc agaaaaatat tatttcctag aatggccatt tgaaaatttt tcatcagagc
      661 cactatctca attgttagaa ttggtttata aggaaacaag ctttccaatg aatttgtcaa
      721 cgcatagaat gctaaagttg ctcctagtta cgaacctata tagaataaag tttggtcatt
      781 ttatggaagt agataaagat tcttttaacg accaaagttt ggatttttta atgcaggcag
      841 aaggaataga aggtgttgct cagagttttg aatcagaata caatatctct ttagatgaag
      901 aagttgtttg ccaattattt gtgtcttact ttcaaaaaat gtttttcata gatgaaagtc
      961 tctttatgaa atgcgtaaaa aaggatagtt atgttgaaaa atcttaccat ctattgagtg
     1021 attttattga tcagatttca gtcaagtatc agattgaaat ggagaataag gataatctga
     1081 tttggcatct gcataatacc gcacatctgt atcgtcaaga gttgtttact gagtttattt
     1141 tatttgatca aaaagggaat acaatcagga actttcaaaa tatttttcca aaatttgttt
     1201 cagatataaa aaaagagctt tctcactatt tagagactct tgaggtttgt tctagttcaa
     1261 tgatggtaaa tcatctatct tataccttca tcactcatac caaacatttg gtgattaatt
     1321 tgctacaaaa tcagcctaaa ctaaaggttt tagttatgag taattttgat cagtatcatg
     1381 caaaattcgt tgcagagaca ctttcttatt actgtagcaa taattttgaa ctggaagttt
     1441 ggactgaatt agaattatca aaggaatctt tagaagattc atcttatgat atcattattt
     1501 ctaattttat tattcctcct attgaaaata agagactcat ctattcaaat aatataaaca
     1561 cggtctcact catatatttg ttaaatgcca tgatgtttat tcgattagat gagtaaccaa
     1621 aaataacaaa aaaacgctat ttcgcgtttg aactgtacct caaaagttag acagaaaaag
     1681 tctaattttt ggggtgtttt tgttaagaaa ataccttcaa tcatttaagc aaaatgtaca
     1741 tctagattta tagccatcta aaactcttgc tttttttgta gaagatacga aaaaagccat
     1801 gaaaccaagg cttttcctgt tttatgtaga tgtttacaca tgaaaattga agtattttca
     1861 aaagctaatt ggagtgattt tattcatgat gggataaatg atctggccaa aaatgattga
     1921 gaaatagttg cttaaaaagc atttgcatga tactatatat tgaaaggagg tgataatatg
     1981 gtagaacaaa gaaaatcaat taccatgaaa gatgttgctt tagaagcagg agttagtgtt
     2041 ggaactgttt cacgtgtaat taataaagaa aaaggcatta aagaagtaac tttgaaaaaa
     2101 gtggaacaag cgattaaaac tttgaattac attccagatt actacgctag aggaatgaaa
     2161 aaaaatcgaa cagaaacgat tgcaatcatt gtaccaagta tctggcatcc cttcttttca
     2221 gaatttgcta tgcatgtgga aaatgaagtc tataagagaa ataacaaatt actcttatgt
     2281 tctatcaatg gtacaaatag agagcaagac tatctggaga tgttgcgtca taataaagtt
     2341 gatggagtgg ttgccattac ctatagtcca attgaacatt acttgacgtc aggaattccc
     2401 tttgttagta ttgaccgcac atactcagat attgccattc cttgtgtttc atcagataat
     2461 gatgcaggtg gaagagaagc agctaaacaa ttaattagta aaggatgtca gcatttagcc
     2521 tttgtgggcg gacataatac aaccattaat gaaaccaaac gtcgtagaat ttcatttgaa
     2581 aagtatgtcc aagagcataa aatacctctt agtatttttg atttggatga gacagttact
     2641 gactattatg gaaagctaga gagtttcttg gaagaaaatt cttctataga tggaattttt
     2701 acaatcaacg attttacagc tttggatgtg attgaaatac taaaaaaaaa tggcaaacgt
     2761 attcctcatg atgttcaaat tattggatac gatggaatta aaatggctgg agatagagat
     2821 tatctacttt caactattga acaaccattg gaagaaatgg caaaagaagc ggttcgtatt
     2881 ttgtttgata taattgatgg aaagactgtt aatttgcaga caatcctacc agtaaaattt
     2941 gttgaaggaa aaacaacaaa aaatgaaaat aagtcttgac agaaagcgct atcaatgata
     3001 gaatgaattc agataaaaag atttattttt aaaacaaaaa tgaaacgttt caaaaaaaga
     3061 aataaagaga cagcgtcaag cgctatcttt tctagaaaaa atgaaacgtt tcaaaaagga
     3121 ggttgctatg aatagcaaag cgaagcaagt ttctctttgg gaaagaatca agaaacaaaa
     3181 actcttgtta ttgatgactg tccccggttt agttttaacc tttatcttta aatacatccc
     3241 tatgtatggg gttttaatcg catttaaaga ttacaatcct ttaaaaggaa ttttagggag
     3301 tgattggatt ggtttttctg agtttacaaa attcatatcc tctcccaact ttggtatctt
     3361 gttagccaac acattaaaat taagtatcta tggtttattg cttggctttt taccaccaat
     3421 cattcttgct attatgctca atcaactctt gagtgaaaaa gtcaaaaaac gaattcagct
     3481 cattttatac gcaccaaact ttatctcagt cgttgttatt gtcggtatga ttttcctctt
     3541 cttttcagtg ggaggaccaa tcaacaattt tctttctatg tttggaatga aggctgactt
     3601 cttgacaaat ccagacttct ttagaccttt atacatcttt agtggtatct ggcaaggaat
     3661 gggctgggct tcaacgctct acacggcaac attggtaaat gtagatccag ccttagtaga
     3721 agcagctcga ctggatggag ccaatatctt ccaacgaatc tggcacattg atattccagc
     3781 tcttaagcct attatggtta tccaatttgt tttagctgca ggtggaatta tgaatgtcgg
     3841 atatgaaaaa gcattcttga tgcagacatc gttaaatttg ccaacttctg aaattatctc
     3901 gacatatgtc tataaagttg gtcttgtatc aggagactat tcttactcaa cagcggttgg
     3961 tttgtttaat gcagtgatta acgtagtatt gcttgttgca gttaaccaaa tcgttaaacg
     4021 catgaataat ggtgaaggaa tttaaggagg aaagtatgaa aaattcgatt atggatacaa
     4081 aatttgatag acgtatctta ctcttaaata aaatcattat tgtctttatc gttttgatga
     4141 ctttgcttcc tttactttat atcgtcgtag catcctttat ggatcctaag gttctggtta
     4201 gtagagggat tagctttaat ccagccgatt ggactgtaga aggttaccag cgtgtattca
     4261 gtgaccaatc tattctaaga ggttttatca attctctact atactctttt ggatttgcag
     4321 ctttaacagt cttgctatct gtgtttacag cttatcctct ttctaagaaa gacttggttg
     4381 gacgtcgttg gattaactac ttcttgattg taactatgtt ctttggtggt ggtttagtcc
     4441 caacttactt gctcgtaaaa gaattgggaa tgctcaatac tccatgggct atcattgttc
     4501 caggtgctgt caatgtttgg aatattattc ttgctagggc ctatttccaa ggattgcctg
     4561 aagaattagt tgaagctgct gtcattgatg gtgcaaatga tttacagatt ttctttaaaa
     4621 tcatgcttcc tcttgcaaaa ccaattatgt ttgttctctt cctctatgct tttgtaggac
     4681 agtggaactc atactttgat gcaatgattt atatcaagga tccaaacttg gaaccattgc
     4741 aacttgtact tcgtaaaatt ctcattcaga gccaaccagg tcaagacatg attggagcac
     4801 aagcggctat gaatgaaatg aaacgtttag ctgaattgat taaatacgca actattgtca
     4861 tttccagctt gccattgatt gttatgtatc cattcttcca aaaatacttt gataaaggaa
     4921 ttatggctgg ttcacttaaa ggataaaaaa agaaaaaata aaaggagttt tctcatgaaa
     4981 ttcaaaacat tctcaaaatc agcagttttg ttgacagcta gtttagcagt acttgcagcc
     5041 tgtggctcaa aaaatacagc ttcaagtcca gattataagt tggaaggtgt aacattcccg
     5101 cttcaagaaa agaaaacatt gaagtttatg acagccagtt caccgttatc tcctaaagac
     5161 ccaaatgaaa agttaatttt gcaacgtttg gagaaggaaa ctggcgttca tattgactgg
     5221 accaactacc aatccgactt tgcagaaaaa cgtaacttgg atatttctag tggtgattta
     5281 tcagatgcta tccacaacga cggagcttca gatgtggact tgatgaactg ggctaaaaaa
     5341 ggtgttatta ttccagttga agatttgatt gataaataca tgccaaatct taagaaaatt
     5401 ttggatgaga aaccagagta caaggccttg atgacagcac ctgatgggca catttactca
     5461 ttcccatgga ttgaagagct tggagatggt aaagagtcta ttcacagcgt caacgatatg
     5521 gcttggatta acaaagattg gcttaagaaa cttggtcttg aaatgccaaa aactactgat
     5581 gatttgatta aagtcctaga agctttcaaa aacggggatc caaatggaaa tggagaggct
     5641 gatgaaattc cattttcatt tattagtggt aacggaaacg aagattttaa attcctattt
     5701 gctgcatttg gtatagggga taacgatgat catttagtag taggaaatga tggcaaagtt
     5761 gacttcacag cagataacga taactataaa gaaggtgtca aatttatccg tcaattgcaa
     5821 gaaaaaggcc tgattgataa agaagctttc gaacatgatt ggaatagtta cattgctaaa
     5881 ggtcatgatc agaaatttgg tgtttacttt acatgggata agaataatgt tactggaagt
     5941 aacgaaagtt atgatgtttt accagtactt gctggaccaa gtggtcaaaa acacgtagct
     6001 cgtacaaacg gtatgggatt tgcacgtgac aagatggtta ttaccagtgt aaacaaaaac
     6061 ctagaattga cagctaaatg gattgatgca caatacgctc cactccaatc tgtgcaaaat
     6121 aactggggaa cttacggaga tgacaaacaa caaaacatct ttgaattgga tcaagcgtca
     6181 aatagtctaa aacacttacc actaaacgga actgcaccag cagaacttcg tcaaaagact
     6241 gaagtaggag gaccactagc tatcctagat tcatactatg gtaaagtaac aaccatgcct
     6301 gatgatgcca aatggcgttt ggatcttatc aaagaatatt atgttcctta catgagcaat
     6361 gacaataact atccaagagt ttttatgaca caggaagatt tggacaaaat tgcccatatc
     6421 gaagcagata tgaatgacta tatctaccgt aaacgtgctg aatggattgt aaatggcaat
     6481 attgatactg agtgggatga ttacaagaaa gaacttgaaa aatacggact ttctgattac
     6541 ctcgctatta aacaaaaata ctacgaccaa taccaagcaa acaaaaacta gaggttgatt
     6601 atgggagata agaaatacac agtagaaaaa gccaatcgtt ttatagcaga aaataaacat
     6661 ctcgttaata ctcaatataa gcctgaagaa catttttcag ctgagattgg ttggatcaat
     6721 gatccaaatg gatttgtcta ttttcgtgga gaataccatc tcttttatca attctatcca
     6781 tatgatagtg tttgggggcc tatgcactgg ggacatgcta aaagtaagga cttggtgact
     6841 tgggagcact tgccagtggc acttgctcct gaccaagatt atgaccgaaa tggttgtttc
     6901 tcaggctctg ccattgtcaa ggatgatcgc ctctggctca tgtacactgg acatatcgaa
     6961 gaagaaaccg gtgtccgcca agtgcaaaat atggcatttt cagatgacgg gattcacttt
     7021 gaaaagattt cccaaaatcc agttgcaact ggatcagact tgccagatga gttgattgct
     7081 gctgatttcc gtgatccaaa actctttgaa aaagatggac gctattactc cgtagtagct
     7141 gccaaacaca aggataatgt gggctgtatc gttctactag ggtccgataa cctagtagaa
     7201 tggcagttcg aatccatctt tttaaaaggg gtagaacacc aaggctttat gtgggaatgc
     7261 ccagattact tcgagttaga tgggaaagat tgccttatta tgtcacccat gcgttatcag
     7321 cgtgagggag actcatatca taacatcaac tcatcgcttt tgttcacggg taaggtagat
     7381 tggggagaaa aatgttttat cccagaatca gttcaagaaa ttgatcatgg ccaagacttc
     7441 tatgcgcctc aaacattgtt ggacgatcaa aatcgtcgta tcctgattgc ttggatgcag
     7501 acatgggggc gtacccttcc aacccatgac caagaacaca aatgggcatg tgccatgact
     7561 ttacctagaa ttctaagatt ggaagatggc aaactaagac aattccctgt taaaaaaggc
     7621 caatatcaaa tccaaataga taaagattgt cattaccact taggaaatga tatagattat
     7681 cttgaatttg gttatgatag taatgcgcag caagtttaca ttgatcgtag ccatcttatt
     7741 caaaaaattc taggtgaaga agaacaggac actagtcgac ggtatgtaga tattgaagct
     7801 aaagaattgg aagttgttct agataaaaat tccatcgaga tttttgtcaa tcaaggtgaa
     7861 gcaagcttga ctgcaactta ttacttaacg gtgccagctg agctatcacg aattgattaa
     7921 aaattaagtt atttctccta aagaaaaagt tctctttcta aaatagtgga aagaggactt
     7981 tttgtgtttt gggtatataa gcttagttta tggtatttgt aaaattggtg ttggattatg
     8041 atttaagcta gttttctaaa gaatttgaaa aaaattttat ttaagcaaaa aaaccttggt
     8101 tccaaggctt ttcctgttgt atttagatgc cccctacagg gatcgaacct gtgacccacg
     8161 gattaagagt ccgctgctct gccagctgag ctaaggaggc aaagaaaaaa gctgtattgg
     8221 tgccgaaact tcacggtttg tattgaaccc gcgcaattaa gcaggtgggc aactcgctct
     8281 aactgaagct gtttccgtgt gagacggcct acatgctgtt agaagacttt tgtttcccta
     8341 ataatacaaa aaatagtcgg tcaacactta agtgtgaagt cgtacaccac agcgtttcta
     8401 tatttatatg ataccacttt ttcaaaaaaa atcaagagga aagtgcagtt ttttgaaaag
     8461 gatttcagat ttttcgcaaa tggtcgatag cttcctttct ttgagccaaa gcccgttcat
     8521 atttaccagt atcttctgct tggaaatagt gatgattacg aattttttct ggcagatagt
     8581 cttgcttgac ccaatttcca ggatagttgt gtggatagag atagtcttgg gcattcccca
     8641 gttccttgct tccactgtag tgcccatcac gcaggtgtcg cggaataggc aagtgccctg
     8701 atgttttgag gtcagcaagt gccttatcca tagctacata ggctgagttg gattttggag
     8761 aaagggccaa atcaatcacg acattggcaa tgagaatgcg ggcttctggg aacccaatct
     8821 tctgggcagc atccagagca gtcacggtat gaatctgggc ctcaggattg gctaagccga
     8881 tatcttcata ggcgataaca gtcaagcgac gagcgagact aggcagatcc ccagcctcaa
     8941 tcaagcgggc agtatagtgg agactggcat ccacatctga gccacgaata gacttttgca
     9001 gggcagatag aacatcatag tgaccgtctc catccttgtc catagtgatg tagcttctct
     9061 gaagactatt ttccatgatg tctaaggtga tgtggcgaat gccctcgtca ttctcagggg
     9121 tagagagaac agctaagtcc agtgagttaa aggcagatcg aaggtctccg tttgtagagg
     9181 ttgcgatgaa atccagcgca tcctcatcta gttctattgg aaaatcaaaa ccacgttcag
     9241 ggttacttag agctatctgc agggcctctt tgacgtcttg gttagacaga ggttccaact
     9301 cgaaaatttg aactcggcta cgaatggcag gagtgacaga gaagaaagga ttttcagtcg
     9361 ttgctccaat catgatgacc agtccacttt ccaagagagg caagaggaag tcttgcttgg
     9421 tcttatctag tcgatgaatt tcgtctagca ataggacgag accaccagaa aatttagctt
     9481 cttccgagat ttcttgcagt cgctttttac tatcaactgt cgcattgaaa gttcgaaagg
     9541 catacttggt cgttccagcg atggcagagg caatactggt tttgccgatt ccaggagggc
     9601 catatagaat catggaggac aggcggttgg cttccaccat gcggcggatg atttttccag
     9661 gtccgaccag atgctcctga ccgatgacct ggtcgatggt tttagggcgc atgcgaagcg
     9721 cgagattgtc tggcatagca gtcctttcta acgtagattt gagtagaatg actcatctac
     9781 tatatcttac tatgtccatt ctagcctatt agttgtgata tttcaatggt tttgtaataa
     9841 tcagggagtg agatagaatc ttttttacta tttaatttaa tgaggagagg tatcagcatg
     9901 agagatttga ttttccttaa agctcaaaat aggatagttg agcctaaaga agtggaagtg
     9961 ctgacttgag aaataatatt gctaaatgtc attgtatgaa ctataatgaa aagagaggtg
    10021 ataagcaatg gaaatgatgg aactaccaag tcaggaaatt ttgattttta caaaacaaat
    10081 tcgtcattgg attcttagtg atcaagttat ttcagggaaa agaaaacttt tcttctggga
    10141 agatactcca aaagagattt tagatttgta cgaaaacatt aaatctaaac ttgattttgc
    10201 ttaccaagaa gttcattcta ataatgggtt gaaaaaatat gaaaaataga ataattgatg
    10261 tttttgaagt agtaaatcgc ctccttgtaa taactgttga aaatcctgat ttcgaagact
    10321 tgagagttaa tcatactcaa tgaaaatcaa agagcaaact aggaaactag ccgcaggctg
    10381 tacttgagta cggtaaggcg acgttgacgt ggtttgaatt tgattttcga agagtatcag
    10441 tttgtaaaaa ttggagataa aaaatataga gtacgcagtg gtcctatgat tcattcaact
    10501 ccgcctcaat ctgtcttaga tcgagatact tttacaattg actatacaga tgatgaattg
    10561 ctcgataaag aagcagtttt tactactcat tagaaaaata ggtatgaata aattggcttc
    10621 ccttagaacc acatctaggg gcttttatgt ataatagaat aataagtatc actcctttac
    10681 aatacgtgta acacgtgtta taatggtgtt gtcaggaggt aaaagcgcta tgcctatgac
    10741 acaaaaagag atggttaaac tccttacggc ccatggttgg ataaagacta gaggcggtaa
    10801 aggctcccat attaaaatgg aaaagcaagg ggaaagacct atcacaatcc ttcatggtaa
    10861 gctgaataag tacactgaaa gagggataag aaagcaagct gggttgtaaa attcagcccc
    10921 tgctttttga tatagaggta gtgaaatgtt agttacgtat ccagctttat tttattatga
    10981 cgacacagac ggaacagaag cgacttattt tgtccatttc ccagattttg aatactcagc
    11041 tacacaagga gaggggattt ctgaggcttt ggctatgggg tcggagtggc tagggataac
    11101 tgttgcagat ttgatagaga gtgatggaga gttacctcag ccatcagata ttaatagctt
    11161 gtctttaatt gataatgatc cttttaaaga tgatgaagat ttcgtgtcaa cctatgacct
    11221 tgataaatct tttatttcta tggtatctgt tgatgtatca gaatacctag gaagtcagga
    11281 acccattaaa aagactttga ctataccaaa atgggcagat aagttgggac gagaaatggg
    11341 acttaacttt tctcagactt tgacagacgc tattgcagat aagaaagttc aagcctaaga
    11401 ttaagcgtgg tatcgtggta atagtcaata aaaaagcacg tccacttgtg ctagttactc
    11461 gcctattgat tttatagatt tattagccct ttcgcgggct ttttatattg atttttatga
    11521 gaaatgaaga aatcagactt ttaagaaaat cattgatacc aagggtttaa atgaggtaat
    11581 atggtataat taggacataa aataattttg tggtaagatg gtagtatcta ttttagcata
    11641 tttccgagca atcggggcga ttaaagagtc gcatagaaag aggacaaaat ggcaacatac
    11701 ggatttttag atattttaga ggaagagttg gacaagaact ttccctttga ctttgagatt
    11761 agttgggaca agcgtaacca tgcggtagaa gtgagttttc tattggaagc gcaaaatgct
    11821 gcaggtgtgg agatggtgga tgaagacgga gaggttttat cagatgacat tctttttgag
    11881 gaagcggtcc ttttctacaa tcctgccaag tcaacagtca atgaggaaga ctatttgact
    11941 gttattcctt acctgcctaa aaaaggattt tcccgtgaat ttttagctta ttttgcgctt
    12001 ttccttaaag atactgctga ggttgggcta gatgtcctca tggacttttt ggaagaccca
    12061 gaagcagagg aatttgtcat ggaatggaac caagaagtct ttgaagaagg aaaagttggc
    12121 ttggaagagg gagaatttta tccttatcca agatactagg agttggttgg aggtgttatg
    12181 aagaaaattg ggacttattt ggtttatgtg ctagctgttg tctttattat gctagctttt
    12241 gcttgtggaa caatcgcatt tgcagagttg gggtattccg cagttttagc ctttactttt
    12301 ggttatgcct tcgctcttct aagcatgtat ttaattttta ttcttcatga gctgggtcat
    12361 gctttttgtg gctacttgac aggctatcgg ctggtggctt ttggattagg acattttatt
    12421 ttgaccaaaa agtcaggcag gtttcatctt agtagaacag ccattctgaa aaatgttggt
    12481 gctcaataca ttggtttaaa agaggatgaa agcgatcaaa gaatcatcct gatgctttca
    12541 ggaggcttga tggttcatct cggcttgata ttattggcga tagtgtttgg atttttgaca
    12601 agaagctggt attttgcagg gacttggatt tttcttaatt tatctttctt cctaaataac
    12661 attttgccag tcgacatcac cgatggagca aaaatttggg aattactaca acaccctgaa
    12721 aataccaaat acgcctacct ggtattgaga cattctgctc aaactttgct ggctcctcaa
    12781 gaatatgatt tgaaagactt tgttcaagca gttcctgagg atgcacgagg gagttttgcg
    12841 gatggtgtat taggtatgca aggtgaagtt tccattttgg aagggaagga agaagtagct
    12901 aaacagcagt ttcaagcatt acttgagagg gcaactactc cgatgatgca gacagttgcc
    12961 caactatccc tgcttcatat cgccttgttg gaaggagatt ttgagcaagc ggagcaatat
    13021 gctagtattc gacaggtcaa atcgtttctg tctctcaaac tgtccaatct tcaagtgata
    13081 caagcctggt atcaattaaa ggtgaagaaa gatgtagatc gaactcgtaa ggctctcaag
    13141 attgctagac agaaaatgga tagtagtcga atgttgaggg acgagaaacg ctattatgaa
    13201 aacttgttag ccgagctgga aaaggaaatg ttagaaggaa ctgaagatgg aactagaaat
    13261 ttctggtttc ccaggctgta agattgcttt gttttgtgag gataagctct tgactatctt
    13321 acgtgatgat aaggcaagta ttccctgggc caatatgtgg gaactgccag gtggtggacg
    13381 tgaaggtgat gaaagtcctt ttgagtgtgt agcgcgtgaa gtttatgaag aactgggcat
    13441 tcatctgact gaagattgtc tgctttggag taaggtttac ccaagtatgc tttttgcaga
    13501 caaacagtcc gtttttctag ttggtcagtt gacacagaac cagtttgaca gtatcgtatt
    13561 tggagatgaa ggacagggct atcagctgat gaatgttgag gaatttctta gttccagtca
    13621 agttgtccct cagttgcaag agagattaaa agattattta aaagtaagtg attagaaagg
    13681 atggttcagt taaatttcta aactgaaccc gccctaaaca ctgtgccaaa aagataaact
    13741 tctcttagac acaagcgtct tcagagaatt tcctattttg gttttgtgtt ttacgggctt
    13801 ggtatcttaa taatggaaac atggcaagag ttaaaagtta cagtgaagcg tgagggagag
    13861 gagttggttt ccaatctctt gattgagctg ggagcgcaag gagtcgcaat cgaagacagt
    13921 atggactatg tgggaaatgt tgaccgcttt ggcgagattt tcccagaggt ggagcagcaa
    13981 gaagaaatcg ttgtgacagc ctactaccct gacacggtgg atgtgacagt ggttgaggcg
    14041 gacttgcagg ctcgcatatc agaattgacg gattttatgg atttgggaga gttaaaaata
    14101 ggtacgactg ccttggctga ggaagactgg gcagacaact ggaagaaata ctatgagcca
    14161 gctcgtatca ctcatgattt gaccatcgtt ccctcttgga cagactatga ggcgactgcg
    14221 ggagaaaaaa ttatcaagct ggatcctggc atggcttttg gtactggaac ccacccaact
    14281 accaagatga gcctttttgc cttggaacag gttcttcgtg gtggcgaaac ggtgctagat
    14341 gtggggactg gttcaggggt tctctctatt gccagctcgc ttctgggggc taaagaaatt
    14401 ttcgcctatg acctggatga tgtggcggtt cgtgtggctc aggaaaatat tgagctcaac
    14461 cctggcatgg aaaatatcca tgtagcggct ggagatttgc ttaagggtgt ggaaattgag
    14521 gcagatgtga ttgtggctaa tatcttggcg gatatcctca ttcatctaat agacgatgcc
    14581 tatcgtttgg ttaaggacga aggctacctg atcatgagtg gcattatcaa ggacaagtgg
    14641 gacatggtgc gccagtcggc tgagtcagct ggatttttcc tcgaaactca catggttcaa
    14701 ggggaatgga atacctgtgt ctttaagaaa accaaggata tctctggtgt gattggaggc
    14761 tagcatgcag cagtattttg taaaaggcag tgctatctct cctgtcacta tcgaggacaa
    14821 ggaaaccagt aagcatatgt ttcaggttat gcgcttgaaa gaagaggatg aggttacctt
    14881 agtctttgat gatggcatca agcgcttggc gcgcgtgctg gatatggaaa atcgtcagtt
    14941 tgagttggtc caagaattaa atgacaatgt ggaactacca gtccaagtga ccatcgcatc
    15001 tggatttccc aagggagaca agctggagtt catcgctcaa aaagtaaccg aactgggtgc
    15061 tagccaaatc tgggcctttc ctgcagactg gtcagttgcc aagtgggatg gcaagaaatt
    15121 gggtaaaaaa gttgaaaaac tagaaaaaat tgcccttgga gcagccgagc aaagcaagcg
    15181 taatattgta ccaagtatta aacttttcga gaaaaaagca gattttctag ctcagctgga
    15241 ccagtttgac tttatcatag tagcctatga agaatcagct aaagaaggag aagccgctgc
    15301 gcttctgcaa gcagtcactg gtcttgaaac aggagccaaa ctgctcttta tctttggtcc
    15361 agaaggcggt ctctcacctg cagaaatcga aagttttgaa gctaagggag ccgttttggt
    15421 aggcctaggt cctcgtattt tgcgagcaga aacagcaccg ctttacgcct tatcagccct
    15481 tagtgtttta gtagaattag agaaataaga ggaagaaaat ggaacaaaaa caccgttcag
    15541 aatttccaga gaaggaactc tgggacttaa cagccctata ccaagaccgt gaggatttct
    15601 tgcgtgcaat cgagaaagct cgtgaagaca tcaaccagtt tagccgtgat tacaagggca
    15661 atcttcacac ttttgaggat ttcgagaagg cctttgcgga attagaacag atctacattc
    15721 agatgagcca tattggcaac tatgctttta tgcctcagac gacggactat agcaatgacg
    15781 aatttgccaa tattgcccaa gctgggatgg aatttgaaac agatgccagc gtagccttga
    15841 ccttctttga cgatgccttg gtggtagcag acgaggaagt cttggaccgt ttgggtgaat
    15901 tgcctcactt gacggcagct attcgtcagg ccaaaatcaa aaaagcccac tatctagggg
    15961 ctgatgtgga gaaggccttg accaatctcg gtgaagtttt ctatagtccg caggacattt
    16021 atactaagat gcgagctggg gattttgaaa tggctgactt tgaagcccat ggcaagacct
    16081 ataaaaacag ctttgtcacc tatgagaatt tctaccaaaa tcacgaggat gctgaggttc
    16141 gtgagaaatc cttccgttcc ttctcagagg gacttcgtaa gcaccaaaat acggctgcag
    16201 cagcctatct ggctcaggtc aagtctgaaa aactcttggc tgatatgaag ggatacgact
    16261 ctgtatttga ttatcttcta gctgaacaag aagtggaccg tgtcatgttt gaccgccaga
    16321 ttgacctcat catgaaggac tttgcaccag tcgctcagag atacctcaag catgttgcca
    16381 aggtaaatgg tcttgaaaag atgacctttg cagactggaa attggacttg gacagcgccc
    16441 tgaatcctga agtgactatt gacgatgcct atgatttggt catgaagtcg gtagaacctt
    16501 tggggcaaga atattgtcag gaagttgctc gttaccaaga agagcgctgg gtggactttg
    16561 ctgctaacag tggcaaggat tccggtggtt atgcggcgga cccatatcgc gtacaccctt
    16621 atgtactcat gagctggaca ggccgtttga gcgatgtcta taccttgatt catgaaatcg
    16681 ggcattctgg tcaattcatc ttttcagaca atcaccaaag ctatttcaac gcccacatgt
    16741 cgacctatta tgttgaagca ccgtcaacct tcaatgaatt gctactcagt gattacttag
    16801 agaaccagtc taatgaccca cgtcaaaaac gcttcgctct ggctcatcgc ttgacagaca
    16861 cctacttcca taatttcatc acccacctct tggaagccgc cttccagcgt aaggtgtata
    16921 cattgattga agaaggggag acctttggag caagcaagct caacagcatt atgaaggaag
    16981 ttttgacaga tttttggggc gatgccattg aaatcgacga cgatgcagct ttgacttgga
    17041 tgcgccaagc tcactactat atgggcttgt atagttacac ttactctgct ggtcttgtca
    17101 tctcgacagc tggttacctt catcttaaaa actcagaaac tggagctgaa gactggctca
    17161 atctcctcaa atcaggtggt agcaagacac cacttgagtc agccatgatt atcggtgctg
    17221 atatttcaac agacaaacca ctccgtgata ccatccaatt cttgtctgac acagttgacc
    17281 agattatcgc ctacagtgct gagttggggg agtaagggga atagaaaaat tttttagaat
    17341 gatgtttatg ggcttgttaa gcgtcattct atttgtctta gttgtagcta ttttcaaaaa
    17401 tgtcgttgaa ggtcgtgatg ttaaatttga acttactgta gaactggtat tgatagttat
    17461 ttacgtcatt ttatatcaga ttgtatttaa ttgagaattc aatattgagt catttaagac
    17521 tgcctttttg aacagttgct agaaatgtag aggtattgac catgtatcaa gatttactaa
    17581 gaaaaatagc agaagaaaaa ccaaattata accaggagga aatccagtgg ttgcttgatc
    17641 atttgggaga tccttctcca gaaattcgcg atgaccttgt ttttacaagc tttgctagag
    17701 ggattcagga agagctattt acacaggagc aatttcattt cattgctgaa ggggtttcat
    17761 ctgatgtagg actagataaa gagattgata aggtaggtct gccaacactt gaacgttctt
    17821 ttagggcact tgtttatgca aatctcttgt atgcagatgc caaccagcaa tcggtttttt
    17881 atcagggatt acaattagaa attcgtaatg tcttttcaaa tcaaggcttg cactatcttt
    17941 caaaagaaaa ggatacaaca ggtttctcaa gtcagtatgg ttgggttcat gcttttgcac
    18001 atggagccga tttactgaca gaggtggtct gtcatccaga ctttcctata aacagaattc
    18061 atgaagtatt tgacatactt ggccaactat ttaaaagaat gtcgattcgc tttacagatg
    18121 atgaggattg gcgtttagca agagtgatct atgaacctat tttacaaggg aagttggagc
    18181 aagaacaagt agcttcttgg ataaaaactg ttgattttcc gatagaagaa agggaggatt
    18241 tttccaaatt ttccaacttt agatcctgtc tggtggaagt ctatgtccaa cttgaccaga
    18301 gaaatagttt acaagatgag ttgaaagaag ctatccagtc ttttcaatac tagagattag
    18361 ctaatagttc tatgattttc aaaaaatttc caatcaattt tcttgaaacc ctttcctact
    18421 tttgatagac tagtatctag tttttgaaaa aaggagaaag aaaatgaaaa aatttgttgc
    18481 tgagttaatc ggtacgttca tgcttgtgtt cgttgggaca ggagctgttg tttttggaaa
    18541 tggttttgat ggccttggtc accttggaat cgcctttgcc tttggtttgg caatcgtggt
    18601 ggcagcctac tcaatcggaa ctgtttcagg tgctcacttg aacccggctg tttcgattgc
    18661 tatgtttgta aacaaacgtt tgtcatcttc agaacttgta aactacatcc ttggtcaggt
    18721 tgttggagct ttcatcgctt ctggcgctgt cttcttcctc ttggctaact caggtatgtc
    18781 aactgctagt cttggtgaaa atgccttggc aaacggtgtc actgtctttg gtggtttctt
    18841 gtttgaagtc atcgcaactt tcttgtttgt attggttatc atgactgtga cttcagaaag
    18901 caagggcaat ggcccgattg ctggtttggt aatcggtttg tcattgatgg cgatgattct
    18961 tgtcggattg aagattactg gactttcagt aaacccagct cgtagcttgg caccagctgt
    19021 cttggtaggc ggcgcagccc ttcaacaagt ttggattttc atccttgcac caatcgctgg
    19081 tggagttctt gcagcccttg ttgcaaaaaa tttccttgga acagaagaat aattgaaact
    19141 caaaaagcct tgctcctcat cttgaggaac agggcttttt cgtatgatac tcttcgaaaa
    19201 tctcttcaaa ccacgtcagc ttcaccttgt cgtaggtatg gttactgact tcgtcagttc
    19261 tatctgcaac ctcaaaacag tgttttaagc tgacttcgtc agttctatct gcaacctcaa
    19321 aacagtgttt tgagtaacct gcggctaact tcctagtttg ctctttgatt ttcattgagt
    19381 atgactttag cggttgtcaa ttttctctgg ataaaggtcg tgttggaaga ggcgttgttc
    19441 tgccaagccc tcatacttag ttccttgctt accgtagttg tagtaggggt tgattgaaat
    19501 gccaccgcgc ggagtgaatt tcccccagac ttctaaatag cgagggtcta gcaagttgac
    19561 caagtctttc ccgatggtgt tgatacagtt ttcgtggaaa tctccgtggt ttcggtagct
    19621 aaatagatat agtttgaggg attttgactc gacacagagt ttgtcaggaa tgtaggaaat
    19681 atgaatcgtc gcaaagtctg gctgagcagt gatttgtccc agcagagaca tatcgaggat
    19741 atggtgacga atgccctgtt ccttagcgat ttctctatta atttgaattt cgaggtgatg
    19801 acgttggccg taggcaaagg tgacagcttc gactgtttca tagtactcct tccaaaatgg
    19861 gaaatgttca gagcatgcaa aaagctccca ttagggagct aaaaaatacc aaatcgagtt
    19921 tttttagcga tggcatatcc caaacatcgt aatattctac ttatatagta aaa
//
LOCUS       DAVLDI010000042        19610 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLDI010000042 DAVLDI010000000
VERSION     DAVLDI010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19610
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.042"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(151..1119)
                     /locus_tag="VXD01_001575"
     CDS             complement(151..1119)
                     /locus_tag="VXD01_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV0601939.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLNLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            1255..2112
                     /locus_tag="VXD01_001576"
     CDS             1255..2112
                     /locus_tag="VXD01_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV0601940.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            2099..2878
                     /locus_tag="VXD01_001577"
     CDS             2099..2878
                     /locus_tag="VXD01_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV0601941.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            2902..4254
                     /locus_tag="VXD01_001578"
     CDS             2902..4254
                     /locus_tag="VXD01_001578"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV0601942.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            4328..4702
                     /locus_tag="VXD01_001579"
     CDS             4328..4702
                     /locus_tag="VXD01_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV0601943.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            4704..5552
                     /locus_tag="VXD01_001580"
     CDS             4704..5552
                     /locus_tag="VXD01_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV0601944.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            5829..6596
                     /locus_tag="VXD01_001581"
     CDS             5829..6596
                     /locus_tag="VXD01_001581"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV0601945.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            6608..7792
                     /locus_tag="VXD01_001582"
     CDS             6608..7792
                     /locus_tag="VXD01_001582"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV0601946.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLKKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSLLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            7789..9660
                     /locus_tag="VXD01_001583"
     CDS             7789..9660
                     /locus_tag="VXD01_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0601947.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(9803..10987)
                     /gene="mntE"
                     /locus_tag="VXD01_001584"
     CDS             complement(9803..10987)
                     /gene="mntE"
                     /locus_tag="VXD01_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV0601948.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            11291..13987
                     /locus_tag="VXD01_001585"
     CDS             11291..13987
                     /locus_tag="VXD01_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV0601949.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            14000..14791
                     /gene="yghU"
                     /locus_tag="VXD01_001586"
     CDS             14000..14791
                     /gene="yghU"
                     /locus_tag="VXD01_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV0601950.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            14907..15317
                     /locus_tag="VXD01_001587"
     CDS             14907..15317
                     /locus_tag="VXD01_001587"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV0601951.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            15329..16924
                     /locus_tag="VXD01_001588"
     CDS             15329..16924
                     /locus_tag="VXD01_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601952.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            16990..17154
                     /locus_tag="VXD01_001589"
     CDS             16990..17154
                     /locus_tag="VXD01_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV0601953.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            17233..17961
                     /gene="yaaA"
                     /locus_tag="VXD01_001590"
     CDS             17233..17961
                     /gene="yaaA"
                     /locus_tag="VXD01_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV0601954.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(18012..19496)
                     /locus_tag="VXD01_001591"
     CDS             complement(18012..19496)
                     /locus_tag="VXD01_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0601955.1"
                     /translation="MRNLLSTKVQRQLRLMENLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYIPGITKKFICRNHLSIINLVNHLNTLSNEIHLSNTL"
BASE COUNT         5738 a         3675 c         4481 g         5716 t
ORIGIN      
        1 ctctgtaaaa tgatgtaaaa acatttattt aaaagctcaa aatatagctg ttttaaaagg
       61 tattgtaaga tatagtaaaa cgatgtaaag gtatttttaa atgcggatga attataaagc
      121 cacgaatcct atgtgactag tggttctttt ttataaactg gtagagtgtt ttggttgtac
      181 tttttgttca gggtcaatgt agttgatagc gttgttgaca gcagttggag cttctccgag
      241 gcctgtcgca atcagatcaa tttttccgtc atagtagcag cagtcaccga tagcatagat
      301 acctgcttgg ctggattcct gtttgctgtt gacgataatc ttgtgacggt tgaggttgag
      361 cccccagttt ttaaggttac cgacagaaga tttgaaacca tagttgacaa agaggtggtc
      421 taggtcaatg gtttcagttt catcagattt gacttttgtg atttcaagtt tatcaagtgt
      481 ttttccattt ccaaggagtt ggctaggggc gaatggtgtc ttgatggtta cagatgattc
      541 ttgcaaggct tgaacactgt gttccaaggc acggaaatta tctctgcggt gaacaagggt
      601 agttggtgcg attttttcaa aagccaaagc ccaatccaca gccgagtctc ccccaccaag
      661 aatcgtcact ttcttaccag cgtattgctg aatgttagaa acgtggtagt ggatattttc
      721 atagccctca acaccttcaa gttccagcgg acgtggtttg aaggcaccgc cacccatagc
      781 gataatgact gttttagtca ggtgacttcc tttagaagtt gtgatggcaa attcttcttc
      841 ttgtttgtca atctcaagaa ccgtttcatt gagatgaata ggggtatcaa atccatttag
      901 ctgttcaatc aagcggttag tcaactcttc tccagtcagg tttgggaagc ctggtacgtc
      961 taggatttcc ttttcagggt agagaatagc aggttgtcca cctagctggg gaagagagtc
     1021 gatgatttga accttggctt ggcgtaggtg ggcataaaag gctgcaaaaa gcccgacagg
     1081 accaccaccc acaatggtaa tatcatagag ttgagacata gtttctcctt tgttttttct
     1141 agtcagttta ttttatcata tttttgttca atgtaaaatg gactaggata gggaaaaaaa
     1201 tgccagaaaa tggtataata ggacgaaagt gttttgatag ggaggatatc agggatgaat
     1261 tttcaacaat tatccaatct gcaatattgg accagtttgt ttgcaagtcc atggacgata
     1321 gctatcaatc tgattgatat tttgattgtt gcttatattt tataccattt tacaaaagct
     1381 attgcaggaa ccaagattat gattttggta cgtggagttt tggtgtttat tttagctcaa
     1441 atccttgcaa atatgattgg tttgactacg atttcttggt taatcaatca aattattact
     1501 tatggggtta ttgcggcggt tgttatcttc tctccagaga ttcggactgg tttggaacgt
     1561 ttgggaagag cgacagattt cttttccaat gcccctatta gtgctgagga acagatgatt
     1621 cgtgcctttg ttaagtctgt tgaatacatg agtcctcgta aaatcggggc cttggttgct
     1681 attcagcgtg tacgtacctt gcaggagtat atttcgacag gaattccctt ggatgctaag
     1741 atttctgcag aacttctcat taacattttt attcccaaca ctcccctaca tgatggtgcg
     1801 gtgattatca aagaagaacg tatcgctgtg acgtctgcct atctgccctt gacaaaaaac
     1861 acagggattt ccaaggaatt tgggaccaga caccgggcgg ctatcggttt atcagaagtc
     1921 tcagatgcct tgacttttgt cgtatcagag gaaacgggag gaatttcgat aacctataat
     1981 ggaaggttta agcacaacct aacacttgat gaatttgaaa cagaattacg tgaaatctta
     2041 cttccaaaag aggaagtggg tcttagtttt aaagaacgat tgctaggagg atggaaacat
     2101 gaaaaaaaat agtttatata tcatatcctc actctttttt gcttgtgtct tatttgtcta
     2161 tgctacggcg acgaattttc aaaacagtac cagtgctagg caggtaaaaa cggaaaccta
     2221 tactaataca gtaacaaatg tccctattga catacgctat aatagtgata agtattttat
     2281 tagcggtttt gcttcagaag tatcagtggt cttgactggt gcaaatcgcc tatcgctagc
     2341 tagtgaaatg caagaaagta cacgtaaatt caaggttact gctgacctaa cagatgccgg
     2401 tgttggaacg attgaagttc ctttgagcat tgaagattta cccaatgggc tgaccgctgt
     2461 ggcgactccg caaaaaatta cagtcaagat tggtaagaag gctcagaagg ataaggtaaa
     2521 gattgtacca gagattgacc ctagtcaaat tgatagtcgg gtacaaattg aaaatgtcat
     2581 ggtgtcagat aaagaagtgt ctattacgag tgaccaagag acattggata gaattgataa
     2641 gattatcgct gtcttgccaa ctagcgaacg cataacaggt aattacagtg gttcagtacc
     2701 tttgcaggca atcgatcgca atggtgttgt cttaccggca gttatcactc cgtttgatac
     2761 aataatgaag gtgactacaa aaccagtagc accaagttca agcacatcaa attcaagtac
     2821 aagcagttca tcggagacat cttcgtcaac gaaagcaact agttcaaaaa cgaattaaaa
     2881 atagaaaagg attttataac aatgggtaaa tattttggga ctgatggagt ccgtggagaa
     2941 gctaacctag aactaacacc agaattagcc tttaaactag gacgttttgg aggctatgtt
     3001 cttagtcaac atgaaacgga agcgccgaaa gtctttgtag gacgtgacac acgtatttca
     3061 ggggaaatgc tggaatcggc cttggtggca ggtctccttt cagtagggat tcacgtatac
     3121 aaacttggtg tccttgcaac accagcagta gcttacttgg ttgaaactga aggagcaagt
     3181 gccggtgtca tgatttctgc tagccacaac ccagcccttg ataacggaat caagttcttt
     3241 ggcggtgatg gcttcaaact agatgatgaa aaagaagcag aaattgaagc cttgctagat
     3301 gctgaggaag acactcttcc tcgtccaagt gcagaaggct taggaatttt ggtagattat
     3361 ccagaaggct tgcgtaagta tgaaggatac cttgtttcaa ctggaactcc tcttgatgga
     3421 atgaaggttg ccttggatac agctaatgga gcagcttcta ccagtgcccg tcaaatcttt
     3481 gcagaccttg gtgcccaatt gacggttatc ggggaaacac cagacggtct taacatcaac
     3541 cttaatgttg gttcaacaca tccagaagcc cttcaagaag tggtcaaaga aagtgggtca
     3601 gctattggtt tggcctttga tggagacagt gaccgcttga ttgctgttga tgagaatggt
     3661 gacatcgtcg atggtgacaa gattatgtac atcatcggaa aatacctttc tgaaaaagga
     3721 caattggctc aaaatacaat tgtgacaact gttatgtcta accttggttt ccacaaggcc
     3781 ttgaatcgcg aaggtattaa caaggcagtt actgcagttg gtgaccgcta cgttgttgaa
     3841 gaaatgagaa aatcaggcta caaccttggt ggtgaacagt ctggtcacgt tatcttgatg
     3901 gattacaata ccacaggtga tggtcaatta tcagcagttc aattgactaa aattatgaag
     3961 gaaactggta agagcttatc agagttggcg gcagaagtaa cgatttatcc acaaaaatta
     4021 gttaatatcc gagtggaaaa cgtcatgaag gaaaaggcca tggaagtgcc agctatcaag
     4081 gccatcatcg agaagatgga agaagaaatg gcggggaacg gccgtatcct tgttcgtcca
     4141 agtggaacag agcccctctt gcgtgttatg gcagaagcgc ctacaacaga agaagtggac
     4201 tactatgttg ataccatcac agatgtagtt cgtgctgaaa ttgggattga ctaaatccta
     4261 gaaaactaga tgaaaataaa aaattatggt acaatagctt ataatattgt agccgatgga
     4321 gaaagacatg aatcttaaac gtgaacaaga atttgttagt cagtatcatt ttgatgcacg
     4381 taattttgaa tgggaaaatg aaaatggagc tcctgaaacc aaggtggatg tgaatttcca
     4441 attgctccaa catgaccaag aaaatcaagt gacttccttg attgtcatct tgagctttat
     4501 gattgtattt gataagtttg tcattagtgg aacaatctca caagtaaacc atatcgatgg
     4561 ccgtattgtc aatgaaccaa gtgaattgaa ccaagaagag gtggaaacct tggctcgtcc
     4621 atgtttgaac atgctcaatc gtttgactta cgaagtgact gaaattgcat tagacttacc
     4681 aggaattaat ttggagttct aatatgaaat tagctgtttt cacagattcc tctgcttatc
     4741 tcagtgaaga gaccttgcaa agagaagact tgtttgtctt ggatattcct gtcaatattg
     4801 atggtgagga atatgtcgaa ggcatcaatc tgtctgctga ggaattttac caaaaaatgg
     4861 ctcaggcttc tgaattgcct aagaccagtc aaccaagtat tgccaagtta gatgagatct
     4921 taacttcgct caaagaacaa ggctatacac atgccttggg gcttttccta tcttctggaa
     4981 tttcaggttt ttaccaaaat atccagtata tggtcgatga ctatgagggc ttaaccattg
     5041 ctttcccaga cactttgatt acaagtgctc ccctaggcat catggttgaa agcgtcttta
     5101 attggcgtga tcagggcgat gattttgcca gcattcagga taagctagcc attcaaatca
     5161 gccgtacgtc agcctttatc atggtagatg acttggatca tttggtaaaa ggtggacgcc
     5221 tttcaaatgg ggctgccatt ttgggcaatt tgcttagcat taagccaatc ctttatttta
     5281 acgatcaagg tgtgattgaa gtttacgaaa aagttcgtac tgaaaagaag gccaccaagc
     5341 gcttaattga aattatcaag gaaacaacgg cttcaggtca ataccgggtc attgtcattc
     5401 atgggaatgc tcctgaaaag gctgaagaat tgcgtcagca cttgcttgat tttggcttgg
     5461 gttcggatgt ttcacttgct acatttggta gtgtcattgg aacgcaccta ggagcaggaa
     5521 gtattgctct gggttatatt ccagtgattt agttggcgct tctaggctag ttaagatgcc
     5581 ttgtatctta gaaattgaac acggactacc tgcctcttga aaaaagatgc ctgtcttgcc
     5641 tttcgtggaa agtcagtgcc attccctatt tttcagaggc agctaaggtc ctttgtatct
     5701 tgataattga acacgcctgg aaccctgtgt gaaaaagata gttcttccaa gaagtagaca
     5761 cttcttgatt ggaattccta ttttcacttt gtgttcttac ggactttgta tcttagacag
     5821 gagtagagat gagtattcga gtaattattg ccggttttaa gggaaagatg ggccaggctg
     5881 cttgtcagat ggtattgact gatccagact tggacttggt ggcagttttg gatccttttg
     5941 agtctgagtc agaatggcag ggtattcctg ttttcaagga taaggctgat ttagctggtt
     6001 ttgaagcgga tgtctgggta gattttacta ctccagctgt tgcctacgaa aatacacgtt
     6061 ttgctcttga aaatggcttt gctccagtag ttggaacgac tggtttcacg agtgaagaaa
     6121 ttgcagagct aaaagaattt tctcgtgccc aagacttggg tggcctgatt gcccctaact
     6181 ttgccttggg tgctgtctta ctcatgcaat ttgcgacgca ggctgccaaa tatttcccaa
     6241 atgtggagat tattgagctc catcatgaca agaaaaagga tgctccgagt ggaacagcca
     6301 ttaaaacagc tgagttgatg gcagaggttc gagagtccat tcagcaaggc gcagcagatg
     6361 aggaagagct gattgctggt gctcgtggtg ctgactttga tggtatgcgc atccactcag
     6421 ttcgtttgcc aggcttggta gctcatcagg aagtcatctt tggcaatcag ggagaagggc
     6481 tgaccctccg tcatgactcc tatgatcgca tctccttcat gacaggagtc aatttgggaa
     6541 ttaaagaagt tgtcaagcgt catgagcttg tctatggatt agaacactta ttatgagatt
     6601 aacgcaaatg ccttctgaat ttcagaaggc tttaccagta ttagaaaaaa ttaaagaagc
     6661 aggctttgag gcttattttg ttgggggctc tgttcgagat gcccttctcc atagccctat
     6721 ccacgatgtg gatattgcga cgtcttctta tccagaagag accaagcaga tttttccgcg
     6781 aacagccgat atcggaatcg agcatggaac cgtcttggtc ttagatgggg atgaggagta
     6841 tgaggtaaca acctttcgga cagaggatgt ctatgtggac tatcgcagac ccagtgcggt
     6901 ttcctttgta cgatcgctag aagaagacct caaacgccgt gatttcacag tcaacgcctt
     6961 tgccttggat gagacaggag aaatcgttga cttgttccat ggtttagaag atttgaaaaa
     7021 gcaagtcttg cgagcagttg gagtggctag tgagcgtttc aacgaagatg ctttacggat
     7081 tatgcgtggt ttccgttttc aggctagtct tggttttgca cttgagccag aaacatttaa
     7141 agctatgaag accttgacgc cgcttttgga gaaaatttct gtagagcgta ccttcgtcga
     7201 gtttgataaa ctcttgctgg ctccattttg gagaaggggc ttggcttcca tgattgagag
     7261 tcaagcttat gactatctcc ctgatatggc atctagccag gacaagctca acagactgtt
     7321 tgatttggag actgatttta cttttgaatc ctctgaacaa gcctgggcgg ctttactatg
     7381 ggctttggag attgaaaatg cgcagtcact tttgaaatct tggaagacct cacgccagtt
     7441 tgccaagcaa gttcaggatt tgctgattat tttggctctg cgtgaaaatg gagaattgag
     7501 caagcgagat tgttatcgct ttgacataga tttgctttta caggctgaaa atcttcgtca
     7561 agctcaagga aaagaagtca acccacaagc catcacagaa aaataccaaa gcttgactat
     7621 ccatgacaag aaagagattc agattaatgg cggtattttg atcaaggaat atggctatca
     7681 gccaggccca gacttgggag agattttaac agagattgag tttgccattg tcgatggaga
     7741 attggagaat aatcgtgaag ccatccatgc ttacctgagg gagaaaaaat gagtgatttt
     7801 atcgttgaaa aactaagtaa atccgttggt gacaagaccg tttttaggga tatttccttt
     7861 attatccatg acttagacag aattggttta atcggtgtca atgggactgg caagaccacc
     7921 cttttggacg tcctttctgg tgtttctgga tttgatgggg atgtcagtcc tttttcagct
     7981 aaaaatgatt accagattgg ttacttgact caggatcctg attttgatga tagaaagaca
     8041 gttttggata cggttctatc tagtgaactc aaggaaatcc agctcattcg tgagtatgaa
     8101 ttgattatgc tcgactatag tgaggacaag caggcgcgtt tggaacgtgt catggcagag
     8161 atggactctc tccaagcttg ggaaatcgaa agtcaggtca agaccgttct tagcaaattg
     8221 ggcattcaag acttatctac tcctgttggg gaattgtcag gtggtctgag aagacgggta
     8281 cagttggcac aagtcttact tggcaaccac gacctcttgc ttttggatga gccgaccaac
     8341 catctggata ttgcgattat tgagtggctg accctctttt tgaaaaattc taagaagacc
     8401 gtccttttta tcactcacga tcgttatttc ttagacgctt tgtcaacacg gattttcgag
     8461 ttggatcgtg caggcttgac cgagtaccag ggaaattacc aggactatgt tcgcctaaag
     8521 gcggaacagg atgagcgcga cgcggctctt cttcacaaaa aagaacaact ctacaaacaa
     8581 gaattggcct ggatgcgcag acaaccgcag gcgcgtgcga ccaagcagca ggcccgtatc
     8641 aatcgattcc atgatctgaa aaaggaagtt tcaggcagta gtgctgagac agacttgacc
     8701 atgaactttg aaaccagtcg gattgggaag aaagtcatcg agtttcaggc tgtttccttt
     8761 gcctatgaaa acaagcctat tttgcaagat tttaatctct tggtgcaggc caaagaccgt
     8821 atcggaatcg ttggggacaa tggtgttgga aaatcaaccc tgctcaactt gattgcagga
     8881 agtcttgagc caactaaagg acaagttgtg attggggaaa ctgttcgcat cgcctatttc
     8941 tctcagcaaa ttgagggttt ggatgaaagc aagagagtta tcaattacct gcaggaagtg
     9001 gcagaagagg tcaagaccag tggcggttct acgacttcga ttgcagagtt gctggagcag
     9061 ttccttttcc cacgttcgac gcatggaacc ttgattgaga aattgtcagg gggtgagaaa
     9121 aaacgtcttt atctcctcaa actgcttttg gaaaaaccaa atgttcttct tttagacgag
     9181 ccaaccaatg acctagatat tgcaactttg acagtcttag agaatttctt gcaaggtttt
     9241 gcaggtcccg ttttaacagt cagtcacgac cgctatttct tggataaggt agcgaccaag
     9301 attctcgctt ttgaggatgg caagattcgt cctttctttg gtcattacac cgactatctt
     9361 gatgaaaaag cttttgaaac agatatggcc aatcaagtgc aaaaggtcga aaaggaaaaa
     9421 gtggtcaagg ttcgagaaga caagaaacgc atgacctacc aagaaaagca ggagtgggca
     9481 agtattgaag gtgatattga aaccttggaa aaacgtatcg ctgctattga agaggaaatg
     9541 caggctaacg gctctgactt tggtaagctg gctactctcc aaaaagaatt ggatgagaaa
     9601 aatgaagcac tccttgaaaa atacgaacgc tatgagtatc tcagtgaatt tgatagttaa
     9661 gactattcga aaatcaaagt gcaaactatg tcggcttcac attgccgact caagtacagc
     9721 ctgtgaccgg cttcctaatt tgcactttga tttttattga gtataaaaga atagaaaaat
     9781 cccgtctcat gaaaggattt ctctattctt ttttggtttc ttgatgaaag atattttgcc
     9841 aggtttcgtg gcgacgccag atactggtat ggatgatacc atctaactca tagcagatga
     9901 gtttggtttt ttgactgatg gaagtaattt gaatgtcctt tatagcagaa tttaactctt
     9961 ttttggtctt ataagcctct ttatccatct gctctccatc ttggcgaata tagacaaaat
    10021 catcagtcaa gagttcttct agttggtttc cttggtcaat caattgttca cgcataagca
    10081 attttttata gacattgtct aaaatttcat cctcagggat aggtgctggt tcgatatgga
    10141 catcggtatc aaagacgcca aaacgctcct ccagcataga ctcgacctga tccgcgattt
    10201 catggctttc aaaaacagac aagtcaggat tcatctctag tgtaatatcc aggtagatgt
    10261 tgctaccgta ggtgcgacct ctttgcgatt tgaccttgct gattttggga atttccatga
    10321 tagccttttg gtagtcctcg agcaggcggt cgtcaaagcc atctgaaaga ctaaaggaag
    10381 actcgatgaa gatatcatag gcagtcttca agataaagaa agtgatgatg atagcaacca
    10441 gtttatccac aatcggataa ttgaaactac tagctaggat ggcaatggcg gttccaagtg
    10501 aggtaacagc gtcagaaaga ttgtccttag cagctgcctt cagcgccttg gagttggatt
    10561 tcttactgag gcgagtattg tagagataga ccacaaacat aatcgctgca gaaatgattc
    10621 ctagagttgc accaagagga tcaatgaccg tttcttcccg actgagaatc ttttgaatgg
    10681 tatctcttag aacatcgaaa ccgacataga acatgatgat agaagtgatc aagcttgcca
    10741 aatcttcaat cttccaatga ccaaaacggt ggtcacggtc tgcaggctgg cgcgccatcc
    10801 gaatcccgat taagagggcc acatttccaa tgatgtccga tacgttatta aaaccatcgg
    10861 ccaccaaact ggatgaatga aggagatgac cagctgctaa tttagctgca gacaagatca
    10921 aataggtcga aatactgata atggctccac gctcagctaa cttgagattt gagatagatt
    10981 gcttcattca acttcctttc tagtcacata gcattctacc attatactgg ttttcaagga
    11041 aaaattcaaa taaggcagtt tttactcttt gaaaactccc caaaatttgg tataatggta
    11101 ctactcaagg gagtagctgg cagaaacctg tgatagtgtc gtcattccga attttatgct
    11161 gaaaagtatg ctttccggcc ctatcttaaa cagcgagact tgttatgatt aacaggtctc
    11221 tttttgtttg tcgtgaaaag atatgacaga aagagagtct gttttgcaca caatgtcaag
    11281 gaggagacac atgtcaaaag aacaaaaacg ccaagcgttt tatactcaga gccctgaaga
    11341 ggtcttgcag gctgtggatg cgaccgagca aggtttgtca tcaagtgagg cggaaaagcg
    11401 ccttgccgaa tttgggcaca atgaactcga agaaggcgag aaacgatcaa tcttggtcaa
    11461 attcatcgag caatttaagg atttgatgat tatcatccta gttgcggcag caatcttgtc
    11521 agtcgtgact tctggtgggg aagatatcgc agatgccatt atcatcctag ctgtggttat
    11581 catcaacgct gcctttggtg tttaccaaga aggaaaagct gaagaagcta ttgaagccct
    11641 caaatccatg tctagtccag ttgcccgcgt tcttcgtgat ggacacatgg cagagattga
    11701 ctctaaagaa ttggtaccag gcgatatcgt tgcccttgaa gcaggtgacg tggtaccagc
    11761 ggacctacgt ttgatagaag ccaactctct taaaattgaa gaagcagcct tgacaggtga
    11821 atctgtacca gtcgaaaaag acttgtcagt cgagcttgcg acagatgctg gtattggtga
    11881 ccgtgtcaac atggccttcc aaaactcaaa cgtaacctat ggtcgtggga tgggtgttgt
    11941 tgtcaataca ggtatgtaca ctgaagttgg tcatattgct ggtatgcttc aagatgcgga
    12001 tgagactgat acaccactca aacaaaactt gaacaacctt tctaaggtct tgacctatgc
    12061 tatcttggtc attgcccttg ttacttttgt agtgggtgtc ttcattcaag ggaaaaatcc
    12121 acttggtgag ttgttgactt ctgttgccct tgccgttgca gccattccag aaggacttcc
    12181 tgctatcgtt accatcgttc tttctcttgg tactcaagtt ttggccaaac gacattccat
    12241 cgttcgtaag ttgccagcag ttgaaacact tggttcaact gaaatcatcg cttctgataa
    12301 gactggtacg ctgactatga acaagatgac agtcgaaaaa gtcttctacg atgcggttct
    12361 acatgactca gctgatgata ttgaactagg tcttgaaatg ccactacttc gttcagttgt
    12421 cttggccaat gatacgaaaa tcgatgtgga aggtaacttg attggtgacc caaccgaaac
    12481 agcctttatc caatatgcct tggacaaggg ctatgatgtc aaaggtttct tagagaaata
    12541 tcctcgtgta gctgaattgc catttgactc tgaccgtaag ctcatgtcaa cagttcaccc
    12601 attgccagat ggtcgtttcc ttgtagcagt caagggtgcg ccagaccaac tcttaaaacg
    12661 ttgtcttctt cgtgataagg ctggggatat tgctccgatt gatgagaagg ttacaaatct
    12721 cattcataca aacaattctg aaatggctca tcaagccttg cgtgtccttg caggtgctta
    12781 taagattatc gatagtattc cagaaaatct cacttctgaa gagcttgaaa atgatttaat
    12841 ttttactggt ttgattggga tgattgaccc tgaacgtcct gaagccgctg aggctgttcg
    12901 tgtggctaag gaagcgggaa tccgtccaat tatgattaca ggtgaccacc aagacacagc
    12961 ggaagccatt gccaaacgtt tgggaatcat tgacgcaaac gatacagaag gtcacgtttt
    13021 aactggtgct gaactcaatg aactgtcaga tgaagaattt gaaaaagtcg ttggtcaata
    13081 ctctgtttat gcccgtgtgt ctccagaaca caaggttcgt atcgtcaagg cttggcaaaa
    13141 acaaggtaaa gtcgttgcca tgacaggtga cggtgtcaat gacgcgccag ctctgaaaac
    13201 agccgatatc ggtatcggta tgggaatcac tggtacagag gtttctaagg gggcttctga
    13261 tatgattctt gcagatgata actttgcgac tattatcgtc gcagtggaag aaggacgtaa
    13321 ggtcttctca aacattcaaa agactattca gtacctactt tctgctaata ctgctgaagt
    13381 attaaccatc ttcctatcaa ccttgtttgg ttgggatgtc ttacagccgg ttcatctttt
    13441 gtggatcaac ttggtaacgg ataccttccc agctatcgct cttggtgttg aacctgcaga
    13501 acctggtgtc atgaatcata aaccacgtgg acgcaaggca agcttcttct caggtggtgt
    13561 tttgagttct atcatttatc aaggtgtact ccaagcagct cttgttatga gtgtttatgg
    13621 ccttgcgatt gcttacccag ttcatgtggg tgacaatcat gctattcatg cagatgccct
    13681 aacgatggcc tttgcaaccc ttggtttgat tcagctcttc catgcctaca atgtcaagtc
    13741 tgtctaccaa tccatcttga cagttggccc attcaagtct aagaccttta actggtccat
    13801 cttggtatcc tttatccttc tcatggcaac aatcgttgta gaaccgcttg aaggaatctt
    13861 ccacgtaacc aaactagact tgtcacaatg gggaattgtt atggctggaa gcttctcaat
    13921 gattatcatc gtcgaaatcg ttaagtttat tcaacgcaaa ctcggttttg acaagaatgc
    13981 gatttaaggg aggtttcgga tgtcagcata tcaattaccg accgtatggc aggatgaagc
    14041 tagtaatcaa ggagctttta cggggctaaa cagaccaaca gcaggtgccc gtttcgaaca
    14101 aaacttgcca aaaggagaac aagcttttca gctttattca ctgggaacac caaatggtgt
    14161 gaaggttact atcttattgg aagaattact agaagctggt tttaaggaag cggcttacga
    14221 cttgtataag attgctatca tggatgggga tcaattcggc tcagactttg tgaagctcaa
    14281 tccaaattcc aagattccag ccttattgga ccagtcaggt actgaaaacg taagagtctt
    14341 tgagtctgct catattcttc tttaccttgc tgagaaattt ggagcctttt taccaagtaa
    14401 tcctgtggaa aaggtagaag ttttgaattg gctattctgg caagcaggtg cagcaccttt
    14461 tctaggtggg ggatttggac atttcttcaa ttatgctcct gaaaaattgg aatatcctat
    14521 taaccgtttt acgatggaag tgaaacgcca gttggattta ttggataagg aattggctca
    14581 gaaaccttat attgcaggca atgactatac gattgcagat attgctatct ggtcttggta
    14641 tggacagtta gttcaaggaa atctttacca aggttctgca aaattcttgg atgcctcaag
    14701 ttatcaaaat ctagtaaaat gggcagaaaa aattgccaat cgtccagctg ttaagcgtgg
    14761 attggaagta acttatacag aaattaaata gcaaaaaagt catcttcgga tggctttttg
    14821 ctacagttga gggaaagggt ttgcagttat cggcttttgt gctataattg ctataatata
    14881 gtaaaaagca agaggagtgt gaggaagtgg aaaagaaaat tgtgaaggat atcttatttt
    14941 tatctcaagt gtctcagccg gcaagtcagg aggaccttta tcttgccaga gatttgcagg
    15001 atacactctt agcaaatcgt gatacctgtg ttggtctagc tgccaatatg attggggtgc
    15061 agaagcgcgt gattatcttt aatcttggct tggttcccgt ggtcatgttt aacccagtgc
    15121 ttctgtcctt tgaaggatct tatgaggcag aagaaggctg tttgtccttg gtaggtgtga
    15181 gatcaactaa gcgttatgaa accataaggc ttgcctatcg tgacagcaag tggcaggaac
    15241 agaccattac cttgacaggc ttcccagctc agatttgcca gcatgagctg gatcacttgg
    15301 aaggacgaat catttaggag gaaagcaaat gaaacgaata gtctttgaac ttatttttat
    15361 cgcaacgacc tggtatatct ttttaccgcc ccttaacctg accagctggg aatttctctt
    15421 cttcctctgt gggcatttgt tagttgtggc aatcttattt ggctttggca aggggataaa
    15481 ccttgtcaaa acggttcatg tgcgccacgg taaggcggaa gctgccttaa atcttgaggg
    15541 tttcaaaatc aatcggttag ggaaaattct gttagcttcg attggaggaa ttcttctctt
    15601 ggcagctttg gtttccttgg taacttccag catgtttcag gctaaaaatt atgccaatgt
    15661 agtcacagtt acggaaaaag actttactga atttcctaag agtgacacca gtaaggttcc
    15721 tatcctagat agaagtactg ctgaaaaaat tggagaccgc tacttgggtt ccctaaccga
    15781 taaggtgtcg caatacgtag cggcagatac ctatacccaa ttgacaattg atgggaaacc
    15841 ttatcgggtc acaccactag aatatgcaga ccctatcaaa tggtttaaca atcaagccaa
    15901 gggaatcggt gagtatatta aggtggacat ggtaactgga aatgcggatt tggtggactt
    15961 gaagacacca atcaagtatt cagactcgga gtattttaac cgtgatgtca aacgtcacct
    16021 gcgcttgaag tacccgacca aaatctttaa aactccatct tttgaggtgg acgatgaggg
    16081 caatcctttc tatgtagcaa cggtttacca aaagcaattt ggacttgctg ttcctcgtcc
    16141 tgcttcagtc attatcttgg atgctacaaa tggagaaacc aaggaataca gcttatcaga
    16201 tgttccagaa tgggtggaca ggatctatcc agcagaggaa accattgagc aaatcaacta
    16261 caacggcaag tacaaggacg gtttcttgaa tgccatgatt tccaagaaaa acgtgaccca
    16321 gactaccaat ggctataatt acttgtctat cggtaatgac atctatctct acacaggtgt
    16381 gacgtcggct aatgcggatg agagtaatct tggtttcatc cttgaaaata tgcgaacagg
    16441 agaaatcact aagtatagct tggcttctgc gacagaagaa tcagcccgtg aatcagcaga
    16501 aggtgctgtt caggagaaat cctacaaagc aaccttccca atcctcatca acctcaatga
    16561 caagcctctc tacatcatgg gcttgaagga caatgctggc ttggtcaaag agtacgccct
    16621 ggtagacgca gtcgagtacc aaaatgttat cgttgctact acagtggaag agatgctcag
    16681 caagtatgcc aataaaaacg accttgaaat tgacaatgca acgacagaaa gcatcaaggg
    16741 agtagtagca gacctcaaat cagctgttat caagggagac actgtctact tctttaaagt
    16801 tgatggcaag atatacaagg tcaaggcttc agtatccgat gaccttcctt accttgaaaa
    16861 tggtaaaacc ttcgaaggtc aagtaggaaa agacaattat ctcaagacct ttaagctacg
    16921 gtaaaaatag gttttttcag aaagtatatg ttataataga gtaaattaag actaatggag
    16981 gacaaagaaa tgggttttta tttgatggtt gcttcaatgc tactcggact gctcgctttg
    17041 aagataggtt tttctcagtt caaggagaaa aaagataaat tcttatctat cttaacaagt
    17101 ttagctggca cagcccttgt tctcgtggct gtctggttag gatggcccaa ataaatagaa
    17161 aaacctcggt caaaccgagg tttttcaaat gaatttcttg gttgtggcta aaaaatatgc
    17221 tacactatca atatgaaaat tttaatccca acagcaaaag aaatgaacac agacttgcca
    17281 agtatcgagg caattccttt aaaaccagaa agtcagaccg tgcttgatgc cttggctctc
    17341 tattctgcca gtcaattgga gagtttctac aaggtatcag ctgagaaagc ggcggaagaa
    17401 tttcaaaata tccaagcttt gaaaaggcaa actgctcaac actatccagc cttgaaactt
    17461 tttgatgggc ttatgtaccg caacattaag agagataagc tgaccgaggc ggaacaagat
    17521 tatcttgaaa atcatgtctt cattacctcg gctttgtacg gtgttgttcc agccttgtca
    17581 cccatggctc ctcaccgttt ggattttttg atgaaattaa aagtcgctgg taagactttg
    17641 aagagccatt ggaaggcagt ctatgatgaa gctctgaaga aggaagaagt gattttctct
    17701 ctcttgtcat cagagtttga gactgtattt tctaaggaaa tcagagcaaa gatggtgacc
    17761 ttcaaattca tggaggatag aggcggtcag ctgaagattc actcaactat ctccaagaaa
    17821 gcgcgcgggg cctttctaac agctttaata gaaaatcaag tacaaactgt gggggaagca
    17881 cgtcgcttga actttgctgg atttgtttac cgagaagatt tgtcacaacc acagggattg
    17941 gtttttgtaa aggaagtata gaaatcagat aagagaaaag tcagcacgat tatgctgact
    18001 tttttgataa cttataaagt attggacaaa tgaatctcat ttgataaggt gttaagatga
    18061 ttaaccaaat ttatgattga cagatgattt cggcaaataa acttcttggt aatccctgga
    18121 atatagaaat tagacacgat gatatcgtaa tctgtctgat ttaaaatctc aggacttgtt
    18181 tttaattcat cccaaatatc gaaggtaaag cggttattac agtaatagga aagcatatca
    18241 acaaaggtaa gggatatagc atggtcaaag ttactgataa tcaaaacctt gataggtggt
    18301 cgattttcta acaactgagt agagaggttt tcagcatggg ttaagatggt gtacatcaag
    18361 tgttccaact gttcaggatg gtcatgctgt ccaattgcct gacggtattg agccaattct
    18421 tgacgcgcac ttcccataaa gtctgggaag taaacttcaa attttttaat cgtcaatgct
    18481 ttttgttcaa ataagattgg ggtagaaaag atttcctgtc tttcaaagaa agcagtgttg
    18541 tgtaaatgcc aaatcagctc atcgtggtta gtaaaagtaa tcttatattg ttttgatagg
    18601 cgttctaata tttgactaag taattggtaa gagtatcttg cttgactgtt atcttctaaa
    18661 gagttgaaga attcttgagg atctaggaaa atatcattct gaagaaaaga aataaaaatt
    18721 tgagcgattg tatctggagt catttcaagc ccaaaatgtt tagagaaata agcaagtgtc
    18781 tcctggaaat ttggaatgct ctttaaaagc ggataatatt ctttgtaaaa gtggttgggg
    18841 aggtcaatga agtgaccatt tttaaccctg tggatactga tagctatcat cagtttgtac
    18901 attctataaa ttgaaaatcg cattggataa ttcgtgattt tatagaagaa gtcagcaaac
    18961 tctgttaaat cttcctcagg aaggtcagga aaaggccaat ctaggaaata atagcgctca
    19021 gaaaagtatt gggcaaaaaa gtaacgaata tcgatctcat ttccacgtat ctcggatgga
    19081 gtaaaagata attcaatttg aaactgagat gaaagaacct ttgtaatatt tctgcccagt
    19141 cgatagaggt tggcactact aaagtaaaga ttttctattg ttcgataaat aggtagcccc
    19201 tcattgaaga acatatactc tagtaattga aaagattgag aattagcaag aaaatattga
    19261 taaatatctt ctacactagt gttaacttct aaatctatca tgattccgtt aacagaagat
    19321 tggatgttaa tagatggaaa ggcaatacgt aattcattta aatcactttt taagattcgt
    19381 tctgtgcatc ctaatttttc ggctagttca tgtaatttca tccaattacg attctgaatt
    19441 aggttttcca ttaagcgtaa ttgtctttga acttttgtgg ataaaaggtt tctcatacgg
    19501 gtattttctc cataattcat tatatctttt tttgtctaag tagtataaaa aaattagagc
    19561 aagaaaattg tcgttagtaa tcggaaaaat tagaataata taagtggctt
//
LOCUS       DAVLDI010000043        18732 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLDI010000043 DAVLDI010000000
VERSION     DAVLDI010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18732
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.043"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(252..1058)
                     /gene="yidA"
                     /locus_tag="VXD01_001592"
     CDS             complement(252..1058)
                     /gene="yidA"
                     /locus_tag="VXD01_001592"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV0601956.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(1071..2375)
                     /locus_tag="VXD01_001593"
     CDS             complement(1071..2375)
                     /locus_tag="VXD01_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV0601957.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSISFSQEDQDQLASMRKLAE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            2447..2824
                     /locus_tag="VXD01_001594"
     CDS             2447..2824
                     /locus_tag="VXD01_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV0601958.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFTIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWV"
     gene            2915..3247
                     /locus_tag="VXD01_001595"
     CDS             2915..3247
                     /locus_tag="VXD01_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV0601959.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            3259..4830
                     /gene="ffh"
                     /locus_tag="VXD01_001596"
     CDS             3259..4830
                     /gene="ffh"
                     /locus_tag="VXD01_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV0601960.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(5025..6308)
                     /locus_tag="VXD01_001597"
     CDS             complement(5025..6308)
                     /locus_tag="VXD01_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV0601961.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(6660..7373)
                     /gene="rsmG"
                     /locus_tag="VXD01_001598"
     CDS             complement(6660..7373)
                     /gene="rsmG"
                     /locus_tag="VXD01_001598"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV0601962.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            7467..8027
                     /locus_tag="VXD01_001599"
     CDS             7467..8027
                     /locus_tag="VXD01_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV0601963.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            8029..8928
                     /gene="htpX"
                     /locus_tag="VXD01_001600"
     CDS             8029..8928
                     /gene="htpX"
                     /locus_tag="VXD01_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV0601964.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGACEVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALVSAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(8972..10531)
                     /locus_tag="VXD01_001601"
     CDS             complement(8972..10531)
                     /locus_tag="VXD01_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0601965.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYESYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSSIYRLTE
                     HGLELVNLEDV"
     gene            complement(10770..11087)
                     /locus_tag="VXD01_001602"
     CDS             complement(10770..11087)
                     /locus_tag="VXD01_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV0601966.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            11257..11799
                     /locus_tag="VXD01_001603"
     CDS             11257..11799
                     /locus_tag="VXD01_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV0601967.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            11799..12428
                     /gene="nth"
                     /locus_tag="VXD01_001604"
     CDS             11799..12428
                     /gene="nth"
                     /locus_tag="VXD01_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV0601968.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            12639..13160
                     /gene="pyrR"
                     /locus_tag="VXD01_001605"
     CDS             12639..13160
                     /gene="pyrR"
                     /locus_tag="VXD01_001605"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV0601969.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            13179..14102
                     /locus_tag="VXD01_001606"
     CDS             13179..14102
                     /locus_tag="VXD01_001606"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV0601970.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            14152..15231
                     /gene="carA"
                     /locus_tag="VXD01_001607"
     CDS             14152..15231
                     /gene="carA"
                     /locus_tag="VXD01_001607"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV0601971.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRDLTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            15544..18720
                     /gene="carB"
                     /locus_tag="VXD01_001608"
     CDS             15544..18720
                     /gene="carB"
                     /locus_tag="VXD01_001608"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV0601972.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTRLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAIAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         5434 a         3607 c         4209 g         5482 t
ORIGIN      
        1 gtagattcag ggtcaatttg aagagagtat ttaaaatatc ttgggaaatt ataatttctc
       61 cctgtttttt gagtccaatc tatgagtatg agttgcccag gagtaaggcc acattctaat
      121 tcgtttaggt aaaaattgtt acaatcagaa tttgtgtctc tattatgatt attttgtttt
      181 aaattaaata gtttgctaaa aaaattcatt ggattttatt gctaatcaat tcttattgaa
      241 aaatgatact tttacagtac ccatgttcgg atggcgtggg caacgccgga ttcgtcattt
      301 gttttagtga tgtatttggc gatttttttg atttctggat ttccattttc catgacaacg
      361 gggtttccaa cgacttccag catggcacgg tcattttctt cgtcaccgat tgccatggtt
      421 tcatctttgg tcaatcctag tttttcagct aagtgagtaa tagctgaacc cttgtctaca
      481 ttctttttaa ggagttcgag gtagaaagga gcagatttgt tgatagagta gtgctcgtaa
      541 aattcggctg gtattttttc aatcgcagca tcgaggattt ctggttcatc gatgaacata
      601 cacttgacaa tttccttgcc agccatttct tcaggggtac ggtagaagat aggcatgctg
      661 acgagggttg attcgtgtac agtgtatttt ccgatattgc gatttgcagt atagataccg
      721 tccttggtaa tggcatgcat gtggacaccg agcttgcgac tgaggaattc catatccaga
      781 taatcctcat aggtcaagga ttcgctgata atctcatggc cagtagcagt ttcttggaca
      841 agggcaccat tgaaggtcac cacatagtca ccttggtctc tcaactgcaa gtcgtccaga
      901 agtttggcaa cacctgcgat ggggcggcca gttgcaatca cgactttgac accagcttct
      961 ttggcatctt ggatggcaga aaagacttca ggagtgattt ccttttggct gttgactagg
     1021 gttccgtcaa tatcgacggc gattagttta atactcataa atttcctctt ttagttttta
     1081 tttggggtaa aatgatcgtt ctcaatcaag tgtaaaaatt gctgggtgat gcttgcgaag
     1141 atgctgtttt ggtctaacat ttctttcggg aaataaaagc gattatctcc gtggcgactt
     1201 ccagcaaggg attggacgat aggggacagg ctagagagtt ctgccagttc tccatttttt
     1261 tgtaaaatct caatctgtgt ccgtgggttt tcagattcgg gacgatagat atcataaggg
     1321 aggtcaaagt tcttatgaat ggcagtgtag tagtcgggat caaagccgat atcctcagct
     1381 aattttctca tgctggcgag ttggtcttga tcctcttgcg aaaagctaat ggatttaaag
     1441 accttgcggt tgacaaagcg ttgcgataaa tctgcaagaa tcttgtcagg actggtcatc
     1501 caaagctgga agtaggtatt catcacgcca tcatccagag ccagatagtc agtcaaggtc
     1561 acattttttt cgaagaaagg caggaggtgt ggagaagttc gggcaaagaa atccttgtcc
     1621 tcaggataga gttccttggc gcgtttgaga agattctgta ggagaacttc catggcgcgt
     1681 gttgcggggt ggaaataaac ctgcatgtac atctggtagc gactgaggac gtagtcttcg
     1741 atggcgtgca tgccattgcg ctgaaaggcg ataccatttt cgataggacg aatgactcgg
     1801 aggattcgag tcaggtcaaa ttccccatag gatgctcctg taaaatagga gtcgcgcaag
     1861 agatagtcca tgcgatctgc gtcaatctga ctagaaatga gctgcacgac ctgcttatta
     1921 ggataggtat ggtcaatgac actggccacc ttttctggga aatcaggtgc cacttgtagc
     1981 aggacttggt gaatctctgt ctcaggattt tgaataatct cctgagtaat ggcttcatgg
     2041 tctgtatcaa agagattttc aaaagtatgg gagtaggcac catgcccaag gtcgtgtagg
     2101 agagcagcgg tcatggtcaa gagagactcg gcaggattcc attcctcagg atatttttct
     2161 tcgaaaatct ctgtgatgcg tcgtgcaatt tcatagactc ctagacagtg agagaagcga
     2221 ctgtgttctc caccgtggaa ggtataactg gaagttccca gttgtttgat ccggcgcaaa
     2281 cgctgaaatt cttttgtatt aatcaagtca tagatgattt gattattgac atggatgtag
     2341 ttgtgaacag ggtcacggaa tactttttcg ttcatatgac cattatagca aaatcctgct
     2401 ctttttggta aaatagtagg acaagagaca agaaagaggg cctgatgtga agattcggat
     2461 gcgaaataca attcagtttg atgagcagtt ggaagtgatt gaccagcttt atgatgtgga
     2521 agtgcatgaa aaaggagatt atagctacct gcttttctat aatgaggaaa aggaaaaagt
     2581 agtgattaaa tttcatggtc aagaacttgt gatgagtcga ttttccaatc ccaagaccat
     2641 tatgcgcttt ctaaaggata gtgatagttt agcctatatt cccacaccta tgggtatgca
     2701 ggagtttacc atccaaacga gccattatca agttgatagg caaaagattg aactagatta
     2761 tcaactacaa aatcaagagg gacatccctt tgccagctat caattggaaa ttacttgggt
     2821 ctaggctcat gtctttttca aatttagcta tctatcttct tggatcggct tcctagtgtg
     2881 gtagattagg ctaatttttg gtataataaa agttatggaa atcgaaaaaa ccaatcgtat
     2941 gaatgcgctc tttgaatttt atgcggcgct tttgacagat aagcaaatga attatatcga
     3001 gctctactac gctgatgatt acagccttgc tgaaattgcc gaggagttcg gtgtcagtcg
     3061 tcaggctgtc tatgacaata tcaagcgaac agaaaagatt ctggaagatt atgagatgaa
     3121 attgcacatg tactcggact atattgtccg cagtcagatt tttgatcaga ttttggagcg
     3181 ctatcccaag gataactttc tgcaggagca gatagaaatt ttaacaagca ttgataatag
     3241 agaataagag gaagaaaaat ggcatttgaa agtttaacag aacgtttgca gaacgtcttt
     3301 aaaaatctac gtaaaaaagg aaaaatctct gaatctgatg tccaagaggc aaccaaagaa
     3361 attcgcttgg ccttgctcga ggccgacgtt gccttgcctg ttgtaaagga ctttatcaag
     3421 aaagttcgtg agcgtgcagt cgggcatgag gtcattgata cacttaatcc tgcgcaacag
     3481 attattaaaa tcgttgatga ggaactgaca gccgttttag gttctgatac ggcagaaatt
     3541 atcaagtcac ctaagattcc aaccatcatc atgatggttg gtttacaagg ggctggtaaa
     3601 acaacctttg ctggtaaatt ggccaacaaa ctcaagaaag aagaaaatgc tcgtcctttg
     3661 atgattgcgg cggatattta tcgtccagct gccattgacc agcttaagac cttgggacaa
     3721 cagattgatg tgcctgtctt tgcacttgga acagaagtac cagctgttga gattgtacgt
     3781 caaggtttgg agcaagccca aactaatcat aacgactatg tcttgattga tactgcgggt
     3841 cgtttgcaga ttgatgagct cctcatgaat gagcttcgtg atgtgaaagc attggctcaa
     3901 ccaaatgaaa tcttgcttgt cgttgatgct atgattggtc aggaagcagc caatgttgcg
     3961 cgtgagttta atgctcagtt ggaagtgact ggggtcatcc ttaccaagat tgatggcgat
     4021 actcgtggtg gtgctgctct gtctgttcgt cacattactg gaaaaccaat caagttcact
     4081 ggtacaggtg aaaagattac ggacattgaa accttccacc cagaccgcat gtctagccgt
     4141 atccttggca tgggggatat gctcactttg attgagaaag cttctcagga atacgatgaa
     4201 caaaaagccc ttgaaatggc tgagaagatg cgcgaaaaca cctttgattt taatgatttc
     4261 atcgatcaat tagatcaggt gcaaaatatg gggccgatgg aagacttgct caagatgatt
     4321 ccaggtatgg ccaacaatcc agcacttcaa aacatgaagg tggatgaacg ccagattgct
     4381 cgtaaacgtg ccattgtgtc ttcgatgaca cctgaagaac gtgaaaaccc agatttgtta
     4441 aatccaagcc gtcgccgtcg tattgctgct ggttctggaa atacattcgt cgaagtcaat
     4501 aaattcatca aggactttaa ccaggctaaa cagctcatgc agggtgttat gtctggggat
     4561 atgaataaaa tgatgaagca aatggggatt aatccaaata accttcctaa aaatatgcca
     4621 aatatgggag gaatggatat gtctgccctt gaaggaatga tgggacaagg cggtatgcct
     4681 gacttatcag ctctcggagg agcaggaatg ccagatatga gccagatgtt tggtggcggt
     4741 ttgaaaggta aaattggtga atttgccatg aaacagtcca tgaaacgtat ggctaacaaa
     4801 atgaagaaag cgaagaagaa acgcaagtaa gacaagagat tgatgcaaat ctcatttgat
     4861 gagaaaataa agtaaaaatt tctatgataa aacgtacagt atcaaggttt tagaatatct
     4921 gatattatac gttttttgat tttaataatt ttgttaagac acttttatta taatatacga
     4981 aaaatccact cagctgtctg agtggattag gtgtatttag actcttagtc tttattttcg
     5041 tatggcaaga tcaagttcaa gatgattcct gtcatggctg aaagggcagt acctgaaagt
     5101 gtaactggac caagtttaag gatagctcct ccaagtccaa gaaccaacat agcacttgcg
     5161 atgatgaggt ttcgcatttg agcgaaatca acacgttctt taatcaagac tttcaaacca
     5221 ttgctggcga taaccccata gagaaggatt gacataccac caagtacagc gtttggaata
     5281 gttgaaatca aggcagtgaa tttaccaagg aagctgaggg caatcgcgat gaaggcagcg
     5341 ttacggataa ctgagacaga agcgatacga gtcataccga taacccctgt attttctccg
     5401 taagttgtat tggctggtcc accaaggaag gcagaaacag aagttgcgat accgtcacca
     5461 agaagagtac ggtgaagacc tggttctttt aagaattgac gaccacagat ttgacccaaa
     5521 acagtatggt ctccgatatg ttcagaaatt gttacgatag cgattggcaa gatagcgatg
     5581 gcttctggac caaagtaaag attgtactct ttaaaggcac cacctgtgct aaatggcaag
     5641 tagaaaccag gaatttcgaa ccagttggct ttaagaactg gtgtaaagtc aaccaagcca
     5701 agagttagtg cgaaaaggta accaccgata atggcaaaga ggaatggaat gattcgtagg
     5761 aagccttttc cttttgtatt gataaaggca gcaattagga aagtaacaac ggctaccaga
     5821 gcatttttcc aatttccgtc tgctacaaga cctgcattgg taacagctga acctgcaagt
     5881 ccaagaccga taacgatgat cataggaccg ataatgattg gtggcaagag tttatcaatc
     5941 cattttgttc ctacaaatcg gatgctggta gcaacaagga catagaccaa accagtcaag
     6001 ataacccctg tttgggcagc agatacatcc ccccccattt ctttcatagc cagtgacata
     6061 gctgtgataa aggcaaatga agaacctaga taaactggaa ctttaaaacc agtagcaatc
     6121 atgtagatga gtgttccaac acctgaagca aaaagggcaa cagatacagg cattcccaaa
     6181 atcaatggta ccaagatggt cgcaccaaac atggcgaaaa cgtgttggaa actaaggaga
     6241 attccttttc catccgaagg acgttggtca acgtctagta acaaatcaac agttgattct
     6301 tgtttcatat aaacctcact tttgggcatc aaaaaagagc ccattatttt acagcaatag
     6361 gccctcagag taagacttct ttaaaattta gattttaaag agttttaaat atttctgcgt
     6421 cttcgtcacc tcacgggatg acattaaaaa cctttgctta ggatagtata gcagaaaaaa
     6481 atgattttgt aaatcatttt ttcccgagcc tagaaataaa agagcgaggc tgattttgta
     6541 aatcattttt tcccgagcct agaaataaaa gagcgaggct gattttgtaa atcatttttt
     6601 cccgagccta aaaataagag agcgaggttg attttgtaaa tattttttta cttaaaaatt
     6661 taaagcgggc gtttatttgg cataccagcc ttacgtggat atttatttgg tgtttctttt
     6721 ttcttttcta ccactgtgat gtaacgcgga tctctatttg gtagggcgta gctgagattg
     6781 tcttcgactt tactaaaaag gagattgagg gcattcttag cttctaacaa ctcctcaggc
     6841 gcattgctgg ccttgagtgc caatagtttt ccaccaacct taaggtaggg aatagtcaat
     6901 tcagatagga cctgcatacg ggcaaccgca cgagctgtta caaaatcata ttgagcacgg
     6961 aagttcttgt cttgggcaaa atcttcggca cgtccgtggt agaaatgaac tccgttcaaa
     7021 tccagttctt gagccaagag ttgtaggaag ttgatgcgct tattgagtga atcaataatg
     7081 gtcacatcta actccggata gagaattttc attggtagac taggaaatcc tgccccagcc
     7141 ccgatatcaa gaagtttgat agtttcattg ggaatcaaac cttgaagaat gggtgcaatc
     7201 gaatcgtaaa aatgtttgag ataaacttct tccttgtccg taatcgccgt caaattaatc
     7261 ttctcattcc actcgaccaa gagctcaaaa taacgttcaa attgttcttt ttgctggtcc
     7321 gaaagtggaa gattctgctc ggcaagcaag ttgtaaaatg tttttggttt catagttatt
     7381 tccttcttta gtatcatctt attttaccac aatcatagaa aatttgatat actggtacta
     7441 atctaaaagc agaaaggact tatattatga cttggattat tcttggagtt ttagctcttg
     7501 ttgttatttt tgtgattgtt agctataacg gtttggttaa aaatcgtatg caaaccaagg
     7561 aggcttggag tcagattgat gttcagttga aacgtcgcaa tgatctcttg ccaaacttga
     7621 ttgagactgt aaaaggttat gccaaatatg aaggttctac ccttgaaaag gtggcagaac
     7681 tacgtaacca agtggcggca gcgacttcac cagcagaagc tatgaaagcc agtgatgccc
     7741 tcactcgtca ggtttcaggt atttttgcag ttgcagaaag ctatccagat ttgaaagcta
     7801 gtgctaactt tgttaaattg caagaggagt tgacaaacac agaaaataaa atttcttact
     7861 ctcgtcaact ctataacagt gttgtcagca actacaatgt aaaattagaa actttcccga
     7921 gcaatattat cgctggaatg tttggattta aagcggcaga tttccttcaa acacctgaag
     7981 aggaaaagtc ggttcctaaa gttgatttta gcggtttagg tgactaagat gttgtttgat
     8041 caaattgcaa gcaataaacg aaaaacctgg attttgttgc tggtattttt cctactctta
     8101 gctcttgttg gttatgcggt tggttatctc tttataagat ctggacttgg tggtttggtt
     8161 atcgcactga ttatcggctt tatctacgct ttgtctatga tttttcaatc gacagagatt
     8221 gtcatgtcca tgaatggagc gtgtgaggtg gatgagcaaa cggcaccaga cctctaccat
     8281 gtagtggaag atatggctct ggtcgctcag attcctatgc cccgtgtttt catcattgat
     8341 gatccagcct taaatgcctt tgcgacaggt tctaatcctc aaaatgcggc tgttgctgcg
     8401 acttcaggtc tactagctat catgaatcgt gaagaactag aagctgttat gggacatgaa
     8461 gtcagtcata ttcgtaatta tgatatccgt atttcgacta ttgcagttgc ccttgttagt
     8521 gctatcacca tgctttctgg tatggcaggt cgtatgatgt ggtggggtgg agcaggtcgc
     8581 agacgaagtg atgatgaccg agatggaaat ggtcttgaaa tcattatgct agtggtttcc
     8641 ctactagcta ttgtactggc acctctcgct gcaaccttgg ttcagctcgc tatttctcgt
     8701 cagagggaat ttctggcaga tgcatctagt gtcgagctga ctcgcaatcc tcagggaatg
     8761 attaatgccc tagataagtt ggacaatagc aaacctatga gtcgccacgt cgatgatgct
     8821 agcagtgctc tttatatcaa tgatcccaag aaaggtgggg ggttccaaaa actcttttat
     8881 acccacccac ctatctcaga acggattgaa cgtttaaaac agatgtaaaa gaatccagag
     8941 gtcgtctctg gatttttgct atgttgcaaa tttatacatc ttctaaatta actaactcca
     9001 aaccgtgttc tgtcaagcgg tagatgcttg aacagacctc ttttaagaaa cgacggtcat
     9061 gcgaaacagt gatgagaccg cctggatagg ttgcaaagag ttttctgatt tggggttgag
     9121 aagtgggaga aaagtttcgt gtgggttcat ccagcaggag aaagtttggt ttgcgcagga
     9181 ctaaatccaa aagcaggagt tttccctgtt gtccgccaga taaggagcga atttgatgct
     9241 gcatttctgg ataactgaaa ttgagactag ctaggtgaga ttggattttc tgtagttcct
     9301 ctttttcccc agttttgctg aggtaggcta ttggtgataa atccaattgc agttttttgt
     9361 ggtaatcttg tggcataaaa ccaagggaaa tctctctttt atcattcaga agttgcttta
     9421 atttggctaa cagagttgat ttcccaacac catttggccc gataataccg attttttctt
     9481 gcccacggac agttagttgt agtttttgaa ccaaaactcg gtcgtcaatg gacaaatttt
     9541 ctttttccag ttggactaag actttagaag ctggtaatgg ttggatgtct gaaaagaaaa
     9601 gttggatttg ttcctcttca agtggctttt gagtcatgga ctgagctgcc ttttcgtagc
     9661 gtttttcttg tgagaggaca gttttcatct ttttagccaa taggcgaccg gcagtactgt
     9721 ctttggtagc tcgaagcgca gtttctacat tttgtttgac tctccgatgt ttttccatgg
     9781 ttttatcgta ggctctttgg ttgttagcag cttgctgact ttgtttggca aaattagcct
     9841 ttctctgctc actatagctt tcatagtcta aatgctctac tagcgtttcc gcttctttac
     9901 ggtgtttgac cagtcgcaag tgaacaatag tgtctgccgt ttcagaaaga aagtcttcat
     9961 catgggaaat gaaaataacg gtttgcctgg tcttttgaat ctggcctttt agccaatcaa
    10021 ctgtctcaag gtctaggtca tttgaaggtt catctaaaaa tagaatctca aagggtttgg
    10081 ctaactcatg gataagctga attttcaaag cttctccccc tgatagattg ccaatctttt
    10141 ggtcacttgc gaaacgattg ctatcaaaat gcaattcctc cgccaaacga tagaggatac
    10201 tgtagtctaa atcaatagaa tctaaaaaga agtagtcgtg taaagttttc tttttcagct
    10261 cctcgggaag tttttgagga atgtaggcca gtgactgata gtcagattgg atgtttccct
    10321 tgatagtgaa atcagacaaa gcttccccca ttaaaatttt aagtaaggtt gatttgccat
    10381 ttccttcttc accaataata gcaacctttt ccccgtcttg gatggtcatg cttaggtcag
    10441 atacaagatc tcgtaaatct ttgttttgtg tgatggttag atgattgatt tttatcatat
    10501 gatttccctt tctagaatgt tcatagtgca taacaaaaag ctctacttta cctagtagag
    10561 cccaaagtct atgtcaaaaa aactctatta acatgccaga aaaagagcat aaaagagcac
    10621 acaaaaagag acaaaaacaa gatctactaa ataaaggttc tttatttgat agacttagtt
    10681 gttcatgtct cccttacctc cgagtattag tatctttata ttataccttt aaggaaattt
    10741 tgtcaacaga aaactggaaa ttctatgctc taaaatccaa aaacaggtcc atagagactt
    10801 agtacgtgtt tgacatgctc gtaatggaat ttatcatagt ttcgccaagc agtgcgtgct
    10861 tgatcgttta gttttaggct acccagtcca atcagaagac tggtgggttg gtaaaatttc
    10921 tcaagatcaa ttaagatact gttgttcaac ttttccgttt ttttgagctc ttgcatagta
    10981 gtgtttagca gctcttgtag tcgaatatca tctgccgtac cctgtttaca gttttgatag
    11041 cttttattta acttggatag gagttgaatg agtttcttgt cttccatgtg agcatcctcc
    11101 ttgatctgat gtactctttc cctatagtat agcactaaaa aacaaaactg tcatagtaaa
    11161 tatgttaaaa ttttgaattt taattacaaa gtttggtgtg ctgatttgta gccttttcat
    11221 ggtataatca agagagtaaa tctttatgga ggaagtatga aattaaatat tcaagaaatt
    11281 cgtaagcagt ctgaaggttt gaactttgaa caaacgttag atttagttga tgacctgcgt
    11341 gcacgtaatc aagaaatttt agatgtaaaa gatatccttg cagttgggaa agtacaatat
    11401 gaagaccgta tgtatttctt agattatcaa ctatcttata ccattgttct tgcttcgagt
    11461 cgcagtatgg agccagttga gttagttgaa tcttatccag tcacggaagt tttcatggaa
    11521 ggtgcaacta accatctaaa tcaagaaatt ttagatgatg acttggtctt gcccatcgaa
    11581 aatgaggcgc ttgaccttgc tgagagtgta tcagacaata tcctgctaaa cattcctatc
    11641 aaggtcttga cggctgaaga agaagctggt caaggattta tctcaggaaa tgactggcaa
    11701 atcatgacag aggaagaata ccaagctcaa aaagcagtaa agaaagaaga aaacagtcct
    11761 tttgctggct tacaaggact atttgacgga gatgaataat ggtcttgtca aaaaaacgag
    11821 cacgaaaggt gctagaagaa atcattgccc tcttcccaga tgccaagcct agtcttgatt
    11881 ttaccaatca ttttgaactc ctggttgcgg tcatgttatc agcccagacg acagatgcag
    11941 cggtaaataa ggccacacca ggtctctttg ttgcctttcc aacaccccaa gctatgtctg
    12001 tagcgacaga gagtgagatt gcttcacata tttctcgctt gggattgtat cggaataaag
    12061 ctaaattcct taaaaaatgt gcccaacagt tactagacga ttttgatggt caagtccctc
    12121 agacacgtga agaattggag agtttggcag gtgttggtcg caagacagcc aatgttgtca
    12181 tgagtgtagg atttgggatt ccagcctttg cagtggatac tcatgtggag cgtatttgca
    12241 aacaccacga tattgtcaaa aaatcagcga cgccacttga ggtggaaaag cgggtcatgg
    12301 atatcttgcc gcctgagcag tggttagctg cccatcaggc catgatttat tttggaagag
    12361 ccatttgcca tccaaaaaat ccagagtgtg accagtaccc acaattatat gattttagca
    12421 atttgtaaga tgctacattg aaactttttg cttgatttta agcatgcttt gtgctatagt
    12481 aaatgataac taaatattcc tttaaacctg tcccgtgagg caggcaagga gcgcgataaa
    12541 gtagaagggt gaagtctata ctgtgtgcag tagggctcgc ttggctataa atttcaagtc
    12601 tccttgttta aggagacttt tctttttgga ggtttgtcat gaaaacaaaa gaagttgtag
    12661 acgaattgac cgtcaaacga gcgattacgc gtattactta tgagattatc gaacgcaaca
    12721 aagatttgaa taagatcgtc ttggctggta ttaaaactcg tggtgtcttt attgcccacc
    12781 gaatccaaga acgtttgaag cagttagaaa atctttcagt tcctgttgtg gaattggata
    12841 ctaaaccttt ccgtgatgat gttaaaagtg gagaagatac ttctttggtt tctgtcgatg
    12901 tgacagaccg cgaagttatc ttggtggatg atgtgctcta tacaggtcgt accatccgtg
    12961 ctgctattga taatattgtc ggtcatggtc gtcctgcgcg tgtgagttta gcagttctag
    13021 tcgatcgtgg acatagagaa ttgccaatcc gtccagatta cgttggaaaa aatatcccaa
    13081 ccagtcgttc tgaagaaatc atcgtagaga tgacagaact tgatgaccaa gacagagttc
    13141 tgattactga agaagcttag aaagttaaag gagtagccat gtcagaaaat caacaagcat
    13201 tgaaccatgt ggtgtccatg gaagacctca ctgtcgatca agtaatgaaa ttgatcaagc
    13261 gaggaattga gtttaaaaat ggagcccagc ttccctatga agaccatccg attgtttcca
    13321 atctcttctt tgaggattct acacggacac ataagtcctt tgaagtcgca gagattaaac
    13381 ttggattgga acgacttgac tttgatgtga agactagttc ggttaataag ggtgagacac
    13441 tttatgacac cattttgact ctgtctgctt taggagtgga tgtctgtgtg attcgccatc
    13501 cagaggtcga ctactataga gaattgattg ctagtccaac gattacgact tccatcatca
    13561 atggtggaga tggttcgggc caacacccta gccagagctt gcttgatttg atgaccattt
    13621 atgaggaatt tggccacttt gagggtctta aagttgctat tgcaggtgac ttggaccact
    13681 cacgcgttgc caaatccaat atgcagattt tgaaacgctt gggatctgaa ctctttttcg
    13741 ctggacctga ggaatggaga agtcaagagt ttgcagacta tggacagttt gtaaccattg
    13801 atgaaatcat tgatcaggtt gatgtcatga tgtttctccg tgtgcaacac gaacgccatg
    13861 atagtggagc tgtattttca aaagaagact accatgccca acatggcttg actcaagaac
    13921 gttacgatcg tttgaaagaa acagcaatcc tcatgcaccc agctccaatc aatcgtgatg
    13981 tagaaatagc agaccacttg gttgaagcac caaaatcacg gattgtccaa caaatgacca
    14041 atggtgtctt tgttcgaatg gcaatcttag aatccgtact agcgagtaga aacgccaact
    14101 aaaacacaag acgttaaaag acgccagtga gcgtccacga gaggtgaaaa tatgacaaaa
    14161 agaattctag tattagaaga tggcacagtt tttgaaggca aggccttcgg agcagatatt
    14221 gatgtaacag gcgaaatcgt ctttaataca gggatgaccg gctaccaaga atccattaca
    14281 gaccagtctt ataatggaca aatcttgacc tttacttatc ctttggtagg aaattatggt
    14341 attaatcgtg atgattatga atccattatt ccaacttgta agggagtcgt tgtttttgaa
    14401 gaagcgcgta gagctagcaa ctggcgcaac caaatgacct tggatgaatt tttgaaagcc
    14461 aagaaaattc cagggatttc aggaattgat acgcgtgatc ttaccaagat tatccgtaag
    14521 catggtacta tgcgtgcaac cttgacccat gttggggaca gtatggacca tgtgacggac
    14581 cagctccaag caacagtttt accgacagac aatatcaaac aggtttctac taaaacgtct
    14641 tatccagctc caggagttgg tttgagcgtg gtgctagtgg actttggtct caagcactca
    14701 atcctacgtg aactttctaa acgcaactgt aacgtgacag ttgttcctta ttcgacaacg
    14761 gctgaagaaa ttctccatct caatcctgat ggagttatgt tgtcaaatgg tccaggtaac
    14821 ccagaagacg ttccacaagc actcgacatg attcgcggtg tacaaggaaa aattccaatc
    14881 tttggtattt gtatgggaca ccaactcttt gcaatggcaa acggggctaa gacctataag
    14941 atgaagtttg gccaccgtgg attcaaccat gcggtacgtg aaatcgcaac aggacgagta
    15001 gacttcacca gccagaacca tggttatgca gtcagccgcg aggatttgcc agagcacttg
    15061 attattaccc acgaagaaat caatgacaag tcagtggaag gtgtgcgcca cagataccaa
    15121 cctgctttct ctgttcaata ccacccagat gcagctcctg ggccacacga cgctagctac
    15181 ctatttgacg agtttatcga gatgatggaa gtttttaaac aatcaaacta agaacgagta
    15241 aaagctcgtc ggagaattta tgtaactgaa cacggacgga aagctcagaa tgtagagaaa
    15301 ccaacttgga ttgtcaatcc ttccttgatt ttctaaaatt caatcgcttt ctattcgtcc
    15361 tttgtatctt atttaatgtc gccctgagag gcgacgaata gaaaggagaa gggtgctccg
    15421 tatttgctga actgaatacg ggctacggat ggtgctaaaa agatagttat tcctagaact
    15481 gacagttctt cgtcataact cctattttag ctttgtccgc ttgacgccct taatatctta
    15541 tatatgccta aacgtactga tattcaaaaa attatggtga ttggttctgg tccgattatt
    15601 attggtcagg ctgctgagtt tgactacgct gggacccagg cttgcttgtc gttgaaagag
    15661 gaaggttatg aggttgtttt ggttaactca aatcctgcaa ccatcatgac ggacaaggaa
    15721 attgctgata aggtttacat tgaaccgatt acacttgagt ttgtgacacg tattcttcgt
    15781 aaggaacgtc cagatgcctt gctaccaaca ctcggtggtc agacaggtct caacatggcc
    15841 atggaattgt ctaaaaatgg catcttagat gagcttggtg tagagcttct cggtactaga
    15901 ttgtctgcca ttgaccaagc ggaggaccgt gacctcttta aacaattgat ggaagagctt
    15961 gagcaaccca ttccagaatc tgaaattgtt aacacagtag aagaagcaat tgcctttgca
    16021 gcgacaattg gctacccagt catcgttcgt ccagccttta cccttggtgg tactggtggt
    16081 ggtatgtgtg ccaacgagaa agaattgcgt gaaatcactg aaaatggttt gaaattgtca
    16141 cctgttaccc aatgtttgat tgagcgttcg attgccggtt tcaaggaaat tgaatacgaa
    16201 gtgatgcgtg actcagctga caatgccttg gttgtttgta acatggaaaa ctttgaccca
    16261 gttgggattc acacagggga ttccattgta tttgcccctg cgcaaaccat gtcagactat
    16321 gaaaaccaaa tgcttcgtga tgcgagcttg agcattattc gtgccctcaa gattgaaggt
    16381 ggatgtaatg ttcagctagc tcttgatcct aacagcttca agtattatgt tatcgaagta
    16441 aaccctcgtg tatcacgttc gtcagccctt gcttctaaag cgacaggata tccgattgct
    16501 aagttggctg ccaagattgc agtaggtttg accttggatg aggttataaa cccagttaca
    16561 ggttcaacct atgccatgtt tgaaccagcc cttgactacg tagttgctaa gattccacgt
    16621 ttcccatttg acaagtttga aaagggtgaa cgccgtctcg gtacacaaat gaaggcgact
    16681 ggagaagtca tggcaatcgg tcgtaacatc gaggaatctc ttctcaaggc ctgccgctcc
    16741 cttgaaattg gggtgcacca caatgaaata cctgaacttg cagcagtttc tgatgatgcc
    16801 ttgattgaaa aggttgtcaa agcccaagat gaccgtctct tctatgtgtc agaagccatt
    16861 cgccgtggtt acacacctga agaaattgca gagcttacaa aaattgatat cttctatctt
    16921 gataaactct tgcatatctt tgaaattgag caagaattgg gtgctcatcc acaagatcta
    16981 gaagttttga aaacagccaa acttaatggt ttttcagacc gtaagattgc tgaactctgg
    17041 ggaacgactg atgatcaagt tcgccaactt cgtttggaaa acaagattgt cccagtttat
    17101 aagatggtag acacttgtgc ggcagagttc gactctgaaa cgccatattt ctattcaacc
    17161 tatggttggg aaaatgaatc tatcagatct gataaagaat ctgtacttgt cctaggttca
    17221 ggtccaatcc gtatcggtca aggggttgag tttgactacg caaccgttca ctctgttaag
    17281 gctatccagg cagctggtta tgaagctatt atcatgaact caaacccaga gaccgtttca
    17341 acagacttct ctgtatcaga taagctttac tttgagccat tgacattcga agatgttatg
    17401 aacgtcattg acttggaaca accaaaggga gttatcgttc agttcggtgg tcaaacagcc
    17461 atcaaccttg cggagccatt ggcaaaagca ggtgtgacca tccttggtac acaggttgct
    17521 gacctagacc gtgccgaaga ccgtgacctc ttcgagcaag ctctcaaaga attggatatt
    17581 ccacagccac caggacaaac ggctaccaat gaagaagaag cagctcttgc agctcgtaag
    17641 attggcttcc cagttcttgt ccgcccatct tatgtacttg gtggacgtgc catggaaatc
    17701 gttgaaaacg aagaagacct tcgttcttac atgcgaactg ctgttaaggc tagtccagac
    17761 cacccagttc ttgtcgactc ttacatcgtt gggcaagagt gcgaagttga tgccatttca
    17821 gatggtaaaa atgtactcat tcctggtatt atggagcata tcgaacgtgc tggtgtccac
    17881 tcaggtgact caatggctgt ttacccacca caaaccttgt cgcaaaaggt tcaggagacc
    17941 atcgcagact acaccaaacg cttagcaatc ggtcttcact gccttggaat gatgaacatc
    18001 cagtttgtta tcaaggatga aaaagtctac gttattgagg tcaatccacg tgccagccgt
    18061 acagttccat tcctatctaa ggtaaccaat attcctatgg ctcaagtagc gaccaagctc
    18121 attcttggtc aaagtttatc agaacttggc taccaaaatg gactttaccc tgaaagcacc
    18181 cgtgttcata tcaaggcacc tgtcttctcc tttaccaaac tagctaaggt agacagcttg
    18241 ctcggtcctg aaatgaagtc aacaggtgaa gttatgggtt ctgatgctac tttggaaaaa
    18301 gctctctata aagcctttga agcttcttat ctacacttgc caacttttgg taatgtcgtc
    18361 tttaccatcg ctgatgatgc caaagaagaa gccttgaact tggctcgtcg tttccaaaac
    18421 attggttatg gaatccttgc gacagaaggg acagcagcct tctttgctag tcatggcttg
    18481 caagcccaac ctgttggtaa gattggtgat gatgataagg atatcccaag ttttgtacgc
    18541 aaaggaagaa ttcaagctat cattaacaca gtaggaacaa aacgaactgc tgacgaagat
    18601 ggtgagcaaa ttcgtcgttc agccattgaa cacggggtgc ccctcttcac agcgctagat
    18661 acagctaatg ccatgcttaa ggtacttgaa agtcgtagct ttgttacaga agcgatttaa
    18721 atagaaaaat aa
//
LOCUS       DAVLDI010000044        18699 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLDI010000044 DAVLDI010000000
VERSION     DAVLDI010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18699
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.044"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            3..1104
                     /locus_tag="VXD01_001609"
                     /pseudo
     CDS             3..1104
                     /locus_tag="VXD01_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1232..1435)
                     /locus_tag="VXD01_001610"
     CDS             complement(1232..1435)
                     /locus_tag="VXD01_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0601973.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1428..2510)
                     /locus_tag="VXD01_001611"
     CDS             complement(1428..2510)
                     /locus_tag="VXD01_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV0601974.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2636..3418)
                     /locus_tag="VXD01_001612"
     CDS             complement(2636..3418)
                     /locus_tag="VXD01_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV0601975.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3418..4761)
                     /locus_tag="VXD01_001613"
     CDS             complement(3418..4761)
                     /locus_tag="VXD01_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV0601976.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4860..6176)
                     /locus_tag="VXD01_001614"
     CDS             complement(4860..6176)
                     /locus_tag="VXD01_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV0601977.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQNLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAANLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6369..7595
                     /locus_tag="VXD01_001615"
     CDS             6369..7595
                     /locus_tag="VXD01_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV0601978.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7794..9368
                     /locus_tag="VXD01_001616"
     CDS             7794..9368
                     /locus_tag="VXD01_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV0601979.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LNEKQTGFVIRNKGDK"
     gene            9633..10421
                     /gene="codY"
                     /locus_tag="VXD01_001617"
     CDS             9633..10421
                     /gene="codY"
                     /locus_tag="VXD01_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV0601980.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            10421..10996
                     /locus_tag="VXD01_001618"
     CDS             10421..10996
                     /locus_tag="VXD01_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV0601981.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            11078..11163
                     /locus_tag="VXD01_001619"
     tRNA            11078..11163
                     /locus_tag="VXD01_001619"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11112..11114,aa:Leu,seq:aag)
     gene            11447..12577
                     /gene="ugpC"
                     /locus_tag="VXD01_001620"
     CDS             11447..12577
                     /gene="ugpC"
                     /locus_tag="VXD01_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV0601982.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(12724..12870)
                     /locus_tag="VXD01_001621"
     CDS             complement(12724..12870)
                     /locus_tag="VXD01_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0601983.1"
                     /translation="MEIKEKTRKLAVSCSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEY"
     gene            13078..13836
                     /locus_tag="VXD01_001622"
     CDS             13078..13836
                     /locus_tag="VXD01_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV0601984.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAIDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13923..14435
                     /locus_tag="VXD01_001623"
     CDS             13923..14435
                     /locus_tag="VXD01_001623"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV0601985.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            14617..15561
                     /locus_tag="VXD01_001624"
     CDS             14617..15561
                     /locus_tag="VXD01_001624"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV0601986.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            15570..16247
                     /locus_tag="VXD01_001625"
     CDS             15570..16247
                     /locus_tag="VXD01_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV0601987.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELFFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            16345..17103
                     /locus_tag="VXD01_001626"
     CDS             16345..17103
                     /locus_tag="VXD01_001626"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV0601988.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            17141..18646
                     /gene="lytC"
                     /locus_tag="VXD01_001627"
     CDS             17141..18646
                     /gene="lytC"
                     /locus_tag="VXD01_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV0601989.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
BASE COUNT         5705 a         3341 c         4137 g         5516 t
ORIGIN      
        1 acatgattaa attgattgat cgttacggaa tagagttcgt caaaaaagga aaaaatcgtt
       61 actattctcc tgatttaaaa caagaaatga ttaatcaagt cttacatgaa ggctggacta
      121 aagatagagt ttctcttgaa tacggcctcc caagtcgtac gatacttctt aactggctag
      181 cacaatacag gaaaaacggg tatactattg ttgagaaaac aagagggaga gtacctaaaa
      241 tgggacgtaa gccaaaaaag agacctgaag agaggacaga attagaatat cttcaagcag
      301 aaaatgagta cctgagagcg gagaatgcca tcctaaaaaa gttaagagaa ctccgattga
      361 aggaggaaaa agagaaagaa gaaagacaga aattgttcaa gaattaatga ctgagttttc
      421 gttagatctt cttctaaaag ccattaaact agctcgttcg acctactact atcacttgaa
      481 acagctagat aaaccagata aggaccaaga gcttaaagct gaaattcaat ccatctttat
      541 cgaacacaag ggaaattatg gttatcgtcg gatttattta gaactaagaa atcgtggtta
      601 tctggtaaat cataaaagag ttcaaggctt gatgaaggta ctcaatttac aagctaaaat
      661 gcgacagaaa cgaaaataaa ggagacgttg gtaagaaggc agagaatctc attcaaggcc
      721 aatttgaagg ctctaaaaca atggaaaagt gctacacaga tgtgacagaa tttgccattc
      781 cagcaagtac tcaaaagctt tacttatcac cagttttaga cggctttaac agcgaaatta
      841 ttgcttttaa tctttcttgt tcgcctaatt tagaacaagt acaaacaatg ttggaacagg
      901 cattcacaga gaagcactat ggtggagtcc ttctttggga ttctgaaatc ggaaatgttt
      961 tatggctatg agaaaacatt taaatcactt aatcaattgg aacaagctat tgtagactat
     1021 attgattact acaacaataa acgaattaag gtaaaactaa aaggacttag ttctgtgcag
     1081 tacagaacta aatcctttgg ataaattaat tgtctaactt ttggggggca gtacatttta
     1141 acacttgata atatgcgttt tattgtggga agattttcct cattttctag tgaaattgaa
     1201 ctttttctaa catcttttga tagatgactt cttaatcaat tatcatttcc attgttgttt
     1261 cttggggttt catcccttgt ctttgataaa agcggagagc accctcgtta tcattccaga
     1321 cacttagggt tagattattg cagccaattt ctttagcata atagcagaaa aatgacaata
     1381 aaatagcccc tagatatttt gaaaggaaag cataggggct atatagttta atcaaaataa
     1441 agcaaatctt tgctggtgct tgtaaagagg tcgaagccat ccttggtaac aacaccgcag
     1501 tcttcaatac gaacaccgac tttaccaggg atatagatac ctggttcaac agagaagcac
     1561 atgccttctt cgatgaccat gtcgtttcct tccatgatag atgggaattc atggacatcc
     1621 ataccgatac catgcccgag acggtggttg aagtactcac cataaccagc tttttcgatg
     1681 acctcacggg cagcgcggtc cacttcatga gcagtcacac ctggcttgat aaagtcaaga
     1741 gcagcttgtt gggcttcaag agtcaagttg taaatatctt tcttgaattg gtctggtttg
     1801 ccgacagcga ctgtacgagt catatctgac gcatagccat tgaccagaac acccaggtca
     1861 aagaggagaa gagcatcatt ttcaacctta ttagctgctg gaatgccgtg tggattcgca
     1921 gcattatcac cagtcaagac catggtatca aagctcattt cgtaaccttc acgtttcatg
     1981 gcaaagtcaa tttgtgcgat gatatctgtc tcagtcttat caagagaaat attgtcaaaa
     2041 ccaacatgaa cagccttgtc agcataaaga cctgcaacca tcattttttg cacttcatca
     2101 gctgatttga tgaggcgcat gcgttggata cgaggagtga ggttgtcaaa ctcagcagtc
     2161 tcaaaaactg ttttcaaacc atggtatttg gtcaagatga gattgtcaaa ctcaacagcg
     2221 acacgtttga agtcaagttg tggaagagca tgtttgattt tttgccatgg attttcagaa
     2281 tcgacatagc ccactactgg gaaggaaacg gtgctacttg cacgttctac ttcaagagct
     2341 gggacaaaga ggagaggttc ctgatccgct aggacaaaga ggaacatttg gcgttcatgg
     2401 ggatcactgt aaaaaccagt gaggtaattg attgtgacgg ggtcagatac gacagcgacg
     2461 tctagttttt ctgattcaag atatgttagg atttgttgta atttagacat atgctacctt
     2521 ctttctaccc ctctattttg gcaaaaaatg agagaaaatg caagggagaa gggtaaaaga
     2581 aaagacaaaa aactccgaca agataacgga gttctttgat atcattttcc tttgtttaag
     2641 aaaagtcagc cttgcttttg acgtcactgt actcttcagc gatttcttgg ctgagaatgt
     2701 cctcataggc agggagttgg atgtcctgac catatttctt cttgagggca gtagtaacta
     2761 ggcgataagc cagattggca ttacgagaga ggataggccc gtggaagtag gaaccaaaga
     2821 cattcttata atgaacccct tcaccgacct tttcttcgtt gtttccattt ccatagacaa
     2881 cctgtcccag cggtttttgg tcatcagaga ggaaggtacg accttggtga ttttcaaatc
     2941 catagtaggt ttcatcgaaa tcttcattgt gaatcttgat gtcaccgata aaacggttat
     3001 tggtctggtt gagcgtgtag tgtcccatga cccctagccc ttcgatacgt tttcctgaag
     3061 cttcaacata atattgaccc aatagttgga aaccaccgca gatagccaga actacaccgt
     3121 cgttttggat gtagttgtca atgctctctt ttttagcagg taggtcgtct gcaatgatac
     3181 tttgttcaaa gtcttgacca ccaccgaaaa aggcgatgtc gtagtgattt tcatcaaagt
     3241 catcatggag agaaacgatg tcaacggtca catgggctcc cagtttttca gccacatact
     3301 tgagcatgag gatgtttcca ttgtccccgt aggtattcat gagatttccg tagaggtggg
     3361 caatgttgag ctgatagggg taattgctat cttttgagga aagtgaagta taaaccatta
     3421 gttcatctcc tttctaacaa tctgacgact agccagcagt tcacgaaatt ccagcatggc
     3481 agtataagtt gccagaatat aggcatgctt gcagtcttga ttctcaatgg tcttgagaac
     3541 ttgctccaga ttactcgttt cagtgatttt ctcagctgga tagccagtca ctcggaggcg
     3601 acgagcgatt tcagaatgac gaacaccgcc agcgttgatt tcaggaatgt ccatgtcagt
     3661 gatttgctca aagtctgcat cccagatcca gctagtgtca attccatctg catagttggc
     3721 attaaggagg acagataggc taaatggata aggtgctagt ttgatcattt cgatagcttg
     3781 ggttgcaccg actggatttt taatcaagac aagggtacat tccttgtcac cgatatgaaa
     3841 ggtttcttgg cgtccaaaga cagcacggct cttgtcaaat ccctgtttga tgagttgcga
     3901 atcggcacct aggaaacggg cgatggccac agcagctagg gcgttataga tattatagag
     3961 cccgccgatt tggataccgt attcttggcc gtctatgaca aagcgagagc gattgttggt
     4021 caactcaacc aattttgtca aacgatagtc gagatcagga cgtttacatc cacaaccttc
     4081 acagatatag gcacccaagt ttgcataggt attatgctca tatttgagga tgccttggca
     4141 gtcaggacag agaatccctt cggtattgta gtgagccagt tgggctggtc ctttttccaa
     4201 gtcaaaacca aaatactcta tagggtttgg aatagttggc ttgtagaaaa gtggactgtc
     4261 tccgttaagg agaacagtag cagttggaac tttccgaatg gcatccaata tcatgttata
     4321 ggtagtatag atttcaccga aacggtccat ctggtcacgg aagatattag taatgacaaa
     4381 aagactaggc tggatatagt cacagatacg agatagactg gcttcgtcaa tttcgaggac
     4441 ggcaatattt tttccagttt tagaagattt ggctgttagg aaggttgttg caatccctgt
     4501 aatcatgttg gcaccgcttg gattggttag aacttgacca tagacctctt ttaaaatgcc
     4561 gacagtgagg gcagttgtca gggtttttcc atttgttcca gtgacaacga caatctcgta
     4621 gttcttagct aggttttgta aaatatcttt atcaaattga agggcgactt tacctgggag
     4681 cgtacttcca cggccaagac ggcttaaaat gaagtgggaa gaacgcccag caagaaggcc
     4741 caaagtagtt tttaagttca tgtttctatt atatcataaa agaggagaaa gacagatttg
     4801 agattccgca gaagtaaaaa cagcccaaag agggctgttc gatacgatta aatctcaact
     4861 taaatcgcaa acaagtcatt caagttctca gccaaggttg ggtgagtgaa gatttgtttt
     4921 gtgaagtaag tgtaaggaat cttgttgtcc atagcaacag taataatgtt gatgatttct
     4981 tgagaacctt ctgagaagat gcttgcacca agaatttctt ttgtttcagt attaacaaca
     5041 gctttgaaag ctccgcgaag gtctccattt acgtgaccac gaggcatggc tgcaacaggg
     5101 atttctttca ctgcgtatgg aagtttcaaa ttagctgctt ggctttcagt caaaccaact
     5161 tgtgaaagtg caggtgtgat gaacatagta tttggcacat tgagacggtc ctcaagtgtg
     5221 tagctgccat ctccagcaag gtagctgtaa acaacacgga agtcatcaag tgaaatgtaa
     5281 gtaaattgaa gaccaccgtt gacatctcca actgcaaaga caccaggaac gtttgtttga
     5341 cagtgtttat ctactttaat agcgccacgt tcagttagtt caatatctgt attttcaagt
     5401 tgaagtggtt ctacatttgg tttgcgtcca gttgcgtaga gaagggcgtc gaaacggtaa
     5461 gtttcgtctt cagttacgac aagcacttgg tcaccgtcgt ttttaatttc agtagtatgg
     5521 atattttgaa gcaattcaat gccatcttct tccatgtatt gtttagcaag agctgcgatg
     5581 gaaggttctg cacgaggaag gaaagtatcc aaggcatcta ggactgtgac cttgcttcca
     5641 agtttgttgt aaaggccggc aaattcaaga ccgatatttc cgccaccaag gattccaagt
     5701 ttttcaggta atttgtccaa gttttggata cctgttgagt caaagatgtt tttgcttgta
     5761 gcaagtccag ggattggcaa gacgtttgaa acagcaccag tgttgatgac gattgtttca
     5821 gcagtcagtt ctttcttttc atcaccagct tggatttcga tgactttatt tgaaaggaag
     5881 tgagcttccg catcaaagat atctacgcct gtaccagcaa cagtcgcata gtttttaccg
     5941 ttgaggcgac cagtgatcgt gtttttagta gcaatcactt cttcaaaaga caagtccttt
     6001 tcagcagcaa ctagcaaggt tttagttggg atacaaccaa tgttgataca agttccaccg
     6061 tacatagcct tgctgcgttc aacgagggca acttttttgc cagctgaagc caatttacct
     6121 gctagtgttt taccagcttt accaaatcca ataacaatta aatcgtatgt taacatttat
     6181 cttcctccta ttcgaatttc attctagcac aagaaaaaaa cttttgcaca attctgctac
     6241 ggaaaagaca gaaaaagata aaaacgcttt ccagacaaaa aactagtaat tttttgacaa
     6301 gcttgataaa ctaaaatcct atctattttt atataagata gaataaatgt tcgaaaatag
     6361 gaggttttat gaaatcgaat cgttatatta ttgcctttgc tggggtcatt ttacacttaa
     6421 tgctgggttc gacttatgct tggagtgttt atcgtaaccc tattattgaa aaaacgggat
     6481 gggatcaggc ttctgttgcc tttgccttta gtctagcaat cttttgtttg ggcttatcgg
     6541 ctgcatttat ggggcgtttg gtagaaaaat ttggtccgag agtcatgggg agtctatctg
     6601 cttttctata cgcaggtgga aatatcttaa caggatttgc aatagaccgt caggaactgt
     6661 ggttgttgta tctagcttat ggcattttag gtgggcttgg tttgggagca ggctatatta
     6721 cccctgtgtc aacgattata aaatggtttc ctgataaacg tggtctcgca acaggtttag
     6781 cgattatggg gtttggtttt gcttctttat tgactagtcc catagcgcaa catctcatcg
     6841 caggggtagg gcttgtagaa actttttata ttttaggtgc aagttacttt attatcatgc
     6901 tcctagcttc acaattcatt aagcgtccaa atgagcaaga gcttgcaatt ttatctgctt
     6961 cagggaaaga aaaaacagac tctctgacgc aagggatgac tgcaaatcag gctctaaaaa
     7021 gcaatcggtt ttatatactt tggattattt tctttatcaa catagcttgt ggtttaggct
     7081 taatttcagc ggcatcgcca atggcacagg agatggctgg cttgtctaca agtcatgcag
     7141 cagtaatggt gggcgtttta gggattttca atggatttgg tcgcttgctc tgggcgagct
     7201 tatctgacta tatcggtcgc cctctaacct ttagtatatt actgcttgtt aatcttttct
     7261 tttctctctc actttggctc tttacagatt ccgttttatt tgtagtcgct atgtctattt
     7321 tgatgacttg ctatggagct ggtttttcat tgatcccagc ttatctcagt gatatttttg
     7381 gaaccaagga attggccgct ctgcatggat atattttaac agcttgggca atggctggtt
     7441 tagcgggacc tattttatta gcagagactt ataaaatggc tcattcgtac acacaaacct
     7501 tgttcgtttt tctcatttta tacagtatcg ccttggcttt gtcttattat ctaggtcgtt
     7561 caatcaaaaa agaaagtcaa aaaccgctta catgattttc tgtagaaatg gggctatctt
     7621 ttgctctggt cttgtgttat actagatagg ttgcaaagaa aacagtactt ttcttttgtg
     7681 gaaaagaagc aacacgattt tatatctagt tatatgaaaa tacgtcataa aaagaaaagt
     7741 ataaactaag ccctataggg tggcttcgca ccacctttag aaagaagaat aacgtgaaat
     7801 ttaatgaatt aaacttgtct gctgatttgc tagcagaaat tgaaaaagct ggttttgtag
     7861 aagctagtcc tatccaagaa caaactattc ctttggccct tgaaggcaag gatgttatcg
     7921 gtcaagctca gactggtaca ggaaaaactg cagcctttgg cttgcctacc cttgaaaaaa
     7981 tccgtacaga agaagcgact atccaagctt tggtcatcgc tccaactcgt gaactagctg
     8041 tccaaagtca agaagaactc ttccgctttg gtcgtagtaa gggagtcaaa gtccgttcag
     8101 tatatggcgg atcaagcatt gaaaaacaaa ttaaggctct taaatctggt gcccatatcg
     8161 tggtgggaac tccaggtcgc ctcttggact tgattaaacg caaggccttg aaattacaag
     8221 acattgaaac ccttatcctt gacgaagcgg atgaaatgct taacatgggc ttccttgaag
     8281 acatcgaagc cattatttcc cgtgtacctg agaaccgtca aactttgctt ttctcagcaa
     8341 ctatgccaga tgccatcaaa cgtatcggtg ttcagtttat gaaagcccct gaacatgtca
     8401 agattgcggc taaggaattg acaacagaat tggttgacca gtactatatc cgtgttaagg
     8461 aacaagaaaa atttgacacc atgactcgtc tcatggatgt ggcacaacca gaactcgcta
     8521 ttgtatttgg tcgtaccaaa cgccgtgtgg atgaattgac tcgtggtttg aaaattcgtg
     8581 gcttccgtgc agaaggaatt catggcgacc tagaccaaaa caaacgtctt cgtgtccttc
     8641 gtgactttaa aaatggcaat cttgatgttt tggttgcgac agacgttgca gcgcgtggtt
     8701 tggatatttc aggtgtgacc catgtctaca actacgatat tccacaagat cctgagagtt
     8761 atgttcaccg tatcggtcgt acaggtcgtg ctggtaagtc aggtcaatct attacttttg
     8821 ttgctccaaa cgaaatgggt taccttcaaa tcattgaaaa cttgactaag aaacgcatga
     8881 aaggtctcaa acctgcaagt gtagaagaat ccttccaatc aaaaaaacag gtagctctca
     8941 agaaaatcga acgtgatttt gcagatgaaa ccattcgtgc caactttgag aaatttggta
     9001 aggatgctcg caaattggct gctgagttta ctccagaaga attggcaatg tatatcttga
     9061 gtctgacagt ccaagaccca gatagccttc cagaagtgga gattgcacgt gaaaaaccac
     9121 taccgtttaa accatcaggt aatggtttcg gtggtaaagc taagggaggt cgtggaggcc
     9181 gtcgtgggga tgaccgtcga gagcgtgatc gccgtggcaa tggtcgccgt gatgagttca
     9241 aaaaaggaag tcgtggcaac gatcgttttg ataaggaaaa acgttaccgt aaggataata
     9301 aaaaaccacg caatacttta aacgaaaagc aaacaggctt tgttattcgt aacaaaggtg
     9361 ataaataaga aaaagcggtt caaaatgaat cgctttttta tataaggaga ccgaatgtga
     9421 aaaagacaaa taaaattatt atattatctt ttataatatt atgatacaaa aaaataggca
     9481 acttgtcaat agaaaaggaa caatttaatt aaaaatattc tggtttttaa ttaaattgta
     9541 agtcaatgca agtcaataag gaattttcag ataattattg aaaaagagac gtttttatgt
     9601 tataatgata gcgattaaat tcgaggtgaa aaatggcaca tttattagaa aaaactagaa
     9661 aaattacatc aattttgaaa cgctcagagg agcagttgca ggatgagctt ccttacaacg
     9721 ctattacgcg tcagttagcg gatattattc attgcaatgc ctgcattatc aatagtaagg
     9781 gacgtctgct tggctatttt atgcgttata aaacaaatac agatcgcgta gagcaattct
     9841 tccaaactaa gattttccca gatgactacg ttcaaggggc taatatgatt tacgaaacag
     9901 aagcaaactt acctgttgag catgatatga gtattttccc tgttgagagt agagatgatt
     9961 ttccagatgg cttgacgact attgcaccga ttcatgtatc ggggattcgc cttggttctt
    10021 tgattatttg gcgtaatgat aaaaaattcg aagatgagga cttggttctt gttgagattg
    10081 ccagtaccgt tgttgggatt cagcttctta acttccaacg tgaagaagat gagaaaaata
    10141 ttcgtcgtcg tactgctgtc accatggcgg tcaataccct ttcttactcc gaactccgtg
    10201 ctgtttcagc aattttaggg gaattaaatg gaaatgaagg gaagttgact gcgtcagtga
    10261 ttgcagatcg tatcggaatc actcgctctg tgattgtcaa tgctcttcgt aaacttgagt
    10321 ctgcggggat tattgaaagt cgctcacttg gaatgaaggg aacctatctt aaggtcttga
    10381 tttcagatat ttttgaagaa gtgaagaaaa gagattacta atgacaaagg ctttaatttc
    10441 gattgattat acagaagatt ttgttgctga tagtgggaaa ctaacagcag gtgctccagc
    10501 tcaggcgatt tcggatgcca tcagcaaggt aactcgatta gcttttgaac gaggagatta
    10561 tatcttcttt actattgatg ctcatgaaga aaacgattgt ttccatccgg aaagtaagtt
    10621 atttcctcct cataatctga ttgggacgag tggacggaat ttatatggag atttggggat
    10681 cttttatcaa gagcatggtt cagacagtcg tgtcttttgg atggataaac gccattactc
    10741 agctttttca gggactgacc tagatattcg tttgagagag cgtagagtgt ctaccgttat
    10801 cttaacaggt gtcttgacgg atatctgtgt cctacataca gctatagatg cctataatct
    10861 aggatatgac atcgagattg ttaaaccagc tgttgcttcc atctggcctg aaaatcatca
    10921 atttgcccta ggtcatttca aaaatacact cggagctaag ttagtagatg aaaatctaaa
    10981 tgaactttct gagtaacctg gttggtgaaa atgaaaaaat ttgaaaaaaa gtgttgacaa
    11041 gcatcccaaa agttgatata ctagtaaagt aatcgacgcg gggatggcgg aattggcaga
    11101 cgcgcaggac taaggatcct gtgaccgctt taggtcgtga gggttcaagt ccctctctcc
    11161 gcataggaaa agagctagct aaagctagct cttttgtatt tctctaaaaa attagaatcc
    11221 agtcaaatgt agtggagaat cagcgaaaat atgggaaaac tgatccttgt ttctgctttt
    11281 gtctatagaa gaataataaa gattatcttc ttcaaattct ccgatattct ctaaagtttt
    11341 gtgcaagttg cacagaactt ttttattttt ttggtcatct tgccatagaa atataaagcg
    11401 ttttcatcta taatataatt atcaaaagac aaaaggagtt cacctcatgg tagaattgaa
    11461 tcttaaaaat atttacaaaa aatatccaaa cagcgaacac tattcagttg aagatttcaa
    11521 cttgaacatc aaagataaag aatttatcgt tttcgtagga ccttcaggat gtggtaaatc
    11581 aactacactc cgtatgattg ctggtcttga agacattaca gaaggtactg catctatcga
    11641 tggcgtggtt gtcaacgacg tagctccaaa agaccgtgat atcgccatgg tattccaaaa
    11701 ctacgctctt tacccacaca tgactgttta tgacaacatg gctttcggtt tgaaattgcg
    11761 taaatacagc aaagaagaca ttaacaaacg tgttcaagaa gcagctgaaa tacttggatt
    11821 gaaagaattc ttggaacgta aaccagctga cctttcaggt ggtcaacgtc aacgtgttgc
    11881 catggggcgt gcgattgtcc gtgatgcgaa agtattcttg atggacgaac ctttgtcaaa
    11941 cttggatgcc aaacttcgtg tatcaatgcg tgctgaaatc gctaaaattc accgtcgtat
    12001 cggagctaca actatctatg taactcacga ccaaacagaa gcgatgacac ttgcagaccg
    12061 tatcgttatt atgtcagcta ctaagaaccc tgctggtaca ggtactatcg gacgtgtaga
    12121 acaaatcggt actcctcaag aagtttacaa aaatccagtt aacaaattcg ttgcaggatt
    12181 catcggaagc ccagctatga acttcatcaa cgtgaaattg gttggtagcg aaattgtttc
    12241 tgacggtttc cgtttgaaag tgccagaagg agcattgaaa gttcttcgtg aaaaaggcta
    12301 cgaaggaaaa gaattgatct ttggtatccg tccagaagac gtgaatgcag aacctgcttt
    12361 ccttgaaaca ttcccagact gtgttgtaaa agcgactatc tctgtatcag aactgcttgg
    12421 ttcagaatct cacctttact gccaagttgg taaagacgag tttgttgcaa aagttgatgc
    12481 tcgtgactac ttgcaaacag gtgcaacagt tgagcttgga tttgacttga acaaagcaca
    12541 cttcttcgat gtagaaactg aaaaaacaat ctactaaaat aaataaaatt caaagcacta
    12601 caagaaaaga tatctcttta tcaattgtag tggagagata tcagttaatc tagggagaga
    12661 aacaaaatgc ttctctcctt tttgctaggg aagtcatatt atgcatctat attgtgatgc
    12721 tctttaatac tcttcgaaaa tctcttcaaa ccacgtcaac gtcgccttgc cgtacgtatg
    12781 attactgact tcgtcagttt tatctgcaac ctcaaagctg tactttgagc agcttacggc
    12841 tagttttcta gttttctctt tgatttccat tgagtattat ttgtgggtac catctacaag
    12901 tgaagctata tgcgtaaact acgtgagcaa ttgaattcga actagagagg taataataaa
    12961 tttatgctat agttatggtg acttgtatgc ttttgattct agtttatcaa ataatagatt
    13021 agaattgtca gataatatca ttttgtgtta taatgaagaa aaaacagagg tgttcaaatg
    13081 tcagaagcag gtcataagtt tttagcaaaa ttggggaaaa aacgcttacg tccaggtgga
    13141 aagcgtgcca cagattggtt aattgcagaa ggaggatttt caaaagaaaa gagaatacta
    13201 gaggttgcgt gtaatagggg aactacagca attgagttgg cacagcgttt tggttgcaag
    13261 ataactgcta ttgatatgga tgctcaagct ttagaagtgg ctaaaaaatc tgctggaacg
    13321 gcaggtgttg ctcatttaat cagttttgaa agagcaaatg caatgaaact tccttatcaa
    13381 gatgctagtt ttgatattgt tataaatgaa gctatgctga ctatgcaagc cgatcaagct
    13441 aagaaaaaat gtgtaatgga atatctaagg gtattaaaac ctggaggtct tctcttgaca
    13501 catgatgtgc ttcttaagga agctaaagag tctatcagac aggaattatc acaagcaatt
    13561 catgtaaatg taggtccttt aactcaagat ggttgggaac aggtgatgat agaatcaggt
    13621 tattgtgatg tgaaagcatt gactggtgaa atgacattaa tgaaattatc gggtatgatt
    13681 tatgacgaag gtttgctagg aactttgaaa atttgtgtaa atgcttgtaa aaaggagaat
    13741 agaaagcagt ttttaactat gtataaaatg tttgctaaga ataaacagaa attgggcttt
    13801 attgcgatgg ctagttataa atcgtcaaaa cgttagataa ttattgaagt taacttttcc
    13861 ttttttcttt cttaaaaaat atgctataat agagagtaaa aaactttgaa agaaagaaaa
    13921 agatgaattt aaaagattac attgcaacaa ttgaaaatta tccaaaggaa ggcattacct
    13981 tccgtgatat tagtcctttg atggctgatg gaaatgctta tagctacgct gttcgtgaaa
    14041 tcgttcagta tgctactgac aagaaagtcg acatgatcgt gggacctgaa gctcgtggat
    14101 ttatcgtggg ttgtccagtt gcctttgagt tgggaattgg ttttgcgcct gttcgtaagc
    14161 caggtaaatt gccacgcgaa gttatttctg ctgactatga aaaagagtac ggtgtcgata
    14221 ccttgactat gcacgcggat gccattaagc caggtcaacg tgttcttatt gtagatgacc
    14281 ttttggcgac aggtggaact gttaaggcaa ctatcgagat gattgaaaaa cttggtggtg
    14341 ttatggcagg ttgtgccttc cttgttgaat tggatgaatt gaacggccgt gaaaaaattg
    14401 gtgactacga ctacaaagtt cttatgcatt attaatgaaa acagtcccta gggctgtttt
    14461 ctctacacta ggatataaaa atagactata actagttaga gaaaaactat aattgaaaac
    14521 tatatcttct tacagtataa taaaaggact aagtgtttga gatttgtctt caaacatatg
    14581 caattattcc tgaaagagta cagttaggag agggttatgc cgattcgaat tgataaaaaa
    14641 ttgccagctg ttgagatttt acggacagag aatatctttg tcatggatga tcaacgtgct
    14701 gcccaccaag atatccgtcc tttgaagatt ttaattttaa atctcatgcc acagaaaatg
    14761 gtcacagaga cccagttgtt gcgccacttg gctaatacac ccctacaact ggatattgat
    14821 tttctctata tggagagcca ccgttctaaa acaactcgtt cagagcacat ggagaccttc
    14881 tataaaactt ttcctgaagt caaggatgag tattttgatg ggatgatcat cacgggtgct
    14941 ccagttgagc atttaccatt tgaggaagtg gactattggg aggaatttag acagatgctt
    15001 gagtggtcta agactcatgt ctattcgacc cttcatatct gttggggggc tcaggctggg
    15061 ctttatctgc gctatggtgt agaaaaatac cagatggaca gtaagctatc aggtatttat
    15121 cctcaggaca ccctaaaaga gggtcacctt ctatttagag gctttgatga tagctatgta
    15181 tcccctcatt cacggcacac ggagatttct aaggaagagg tcttaaacaa gaccaatctc
    15241 gagattttat cagaaggacc tcaggttggg gtttctattt tggccagtcg tgatttacga
    15301 gaaatttata gttttggtca tttggagtat gaccgtgata ccttggcaaa agagtatttt
    15361 cgagatcgtg atgcaggttt cgacccacat attccagaaa attactttaa agatgatgat
    15421 gttaatcagg taccttgtct ttgttggtct tcatctgcag ccctcttttt cagtaattgg
    15481 gtaaaccatg cggtctatca ggagacgcct tttgattgga gaaagataga agatgatgca
    15541 tctgcatatg ggtatttata agaggaatta tgacatattt agacgctttt aaatcaggta
    15601 ccttggtttt accgagtgcc ctgctcttgc attttaagga actctttcct tctagcgacg
    15661 attttctggt ttggcaattt ttctatttgc aaaatacgac aggcttagaa gaaatgtcgc
    15721 caagccagat tgctgaaagg attggcaagg aaatttcgga tgtcaaccag tccatttcta
    15781 atctgacgga aaggggactg ctccagtatc gtactatcga attaaatggc gaaattgaat
    15841 tgttctttga tgctagtttg gccttggaac gtttggatga cctgtttgga gcagttcgtt
    15901 caagttcaga ccagctaaca cctcaaaacc agctcaagga tttggtggaa accttccagc
    15961 aggagttggg acgattgttg acgccttttg agattgagga tttgaccaag acactaaagg
    16021 aagatggaac cagtgctgac ttgattaagg aggctcttcg tgaagctgtt ttgaatggaa
    16081 aaccaaactg gaagtacatt caggcaattt tgagaaactg gcgccatgaa ggaatcaaga
    16141 gtgtggctca aattgaggcc aagagagcag aaagagaagc aagcaatcct cagttgacac
    16201 aggtatctgc agatttcaga aatgccatgg atctctggaa ggattaatcc atgcaagtag
    16261 gcttgaaatc cgagtaagat ttgcaagctg tgtataattg tgatagaata aatagaaaat
    16321 aaattgaaaa aagaggtatg tgaaatgtca cgtaaaccat ttatcgctgg taactggaaa
    16381 atgaacaaaa atccagaaga agctaaagca ttcgttgaag cagttgcatc aaaacttcct
    16441 tcatcagatc ttgttgaagc aggtatcgct gctccagctc ttgatttgac aactgttctt
    16501 gctgttgcaa aaggctcgaa ccttaaagtt gctgctcaaa actgctactt tgaaaatgca
    16561 ggtgctttca ctggtgaaac tagcccacaa gttttgaaag aaatcggtac tgattacgtt
    16621 gttatcggtc actcagaacg ccgtgactac ttccatgaaa ctgacgaaga tatcaacaaa
    16681 aaagcaaaag caatctttgc gaacggtatg cttccaatca tctgttgtgg tgaatcactt
    16741 gaaacttacg aagctggtaa agctgctgaa ttcgtaggtg ctcaagtatc tgctgcattg
    16801 gctggattga ctgctgaaca agttgctgcc tcagttatcg cttatgagcc aatctgggct
    16861 atcggtactg gtaaatcagc ttcacaagac gatgcacaaa aaatgtgtaa agttgttcgt
    16921 gacgttgtag ctgctgactt tggtcaagaa gtcgcagaca aagttcgtgt tcaatacggt
    16981 ggttctgtta aacctgaaaa tgttgcttca tacatggctt gcccagacgt tgacggtgcc
    17041 cttgtaggtg gtgcgtcact tgaagctgaa agcttcttgg ctttgcttga ctttgtaaaa
    17101 taatcagtaa gtagcaaaag ctaggtggaa cagcattcag atgtctgtta cattttttat
    17161 aggagaggaa agattgaaaa taaaaattgg attagcaagt atctgtttac taggcttggc
    17221 aactagtcat gtcgctgcaa atgaaactga agtagcaaaa acttcgcagg atacaacgac
    17281 agcttcaagt agttcagagc aaaatcagtc ttctaataaa acgcaaacga gcgcagaagt
    17341 acagactaat gctgctgccc actgggatgg ggattattat gtaaaggatg atggttctaa
    17401 agctcaaagt gaatggattt ttgacaacta ctataaggct tggttttata ttaattcaga
    17461 tggtcgttac tcgcagaatg aatggcatgg aaattactac ctgaaatcag gtggatatat
    17521 ggcccaaaac gagtggatct atgacagtaa ttacaagagt tggttttatc tcaagtcaga
    17581 tggggcttat gctcatcaag aatggcaatt gattggaaat aagtggtact acttcaagaa
    17641 gtggggttac atggctaaaa gccaatggca aggaagttat ttcttgaatg gtcaaggagc
    17701 tatgatgcaa aatgaatggc tctatgatcc agcttattct gcttattttt atctaaaatc
    17761 cgatggaact tatgctaacc aagagtggca aaaagtgggt ggcaaatggt actatttcaa
    17821 gaagtggggc tatatggctc ggaatgagtg gcaaggcaac tactatttga ctggaagtgg
    17881 tgccatggcg actgacgaag tgattatgga tggtgctcgc tatatctttg cggcttctgg
    17941 tgagctcaaa gaaaagaaag atttgaatgt cggctgggtt cacagagatg gtaaacgcta
    18001 tttctttaat aatagagaag aacaagtggg aaccgaacat gctaagaaaa tcattgatat
    18061 tagtgagcac aatggtcgta tcaatgattg gaaaaaggtt attgatgaga acgaggtgga
    18121 tggtgtcatt gttcgtctag gttatagcgg taaagaagac aaggaattgg cgcataacat
    18181 taaggagtta aaccgtctgg gaattcctta tggtgtctat ctctatacct atgctgaaaa
    18241 tgagaccgat gctgagaatg acgctaaaca gaccattgaa cttataaaga aatacaatat
    18301 gaacctgtct taccctatct attatgatgt tgagaactgg gaatatgtaa ataagagcaa
    18361 gagagctcca agtgatacag acacttgggt taaaatcatc aacaagtaca tggacacgat
    18421 gaagcaggcg ggttatcaaa atgtgtatgt ctatagctat cgtagtttat tacagacgcg
    18481 tttaaaacac ccagatattt taaaacatgt aaactgggta gcggcctata cgaatgcttt
    18541 agaatgggaa aacccttatt attcaggaga aaaaggttgg caatatacct cttctgaata
    18601 catgaaagga atccaagggc gcgtagatgt cagcgtttgg tattaagcga tgatttgaaa
    18661 gagggatgtg atagtagcac cctctttttc tttgtttta
//
LOCUS       DAVLDI010000045        18449 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLDI010000045 DAVLDI010000000
VERSION     DAVLDI010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18449
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.045"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(100..909)
                     /locus_tag="VXD01_001628"
     CDS             complement(100..909)
                     /locus_tag="VXD01_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0601990.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKYDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(911..1714)
                     /locus_tag="VXD01_001629"
     CDS             complement(911..1714)
                     /locus_tag="VXD01_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV0601991.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1724..3211)
                     /gene="tacF"
                     /locus_tag="VXD01_001630"
     CDS             complement(1724..3211)
                     /gene="tacF"
                     /locus_tag="VXD01_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV0601992.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3547..4254
                     /locus_tag="VXD01_001631"
     CDS             3547..4254
                     /locus_tag="VXD01_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV0601993.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFVDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4259..5281
                     /locus_tag="VXD01_001632"
     CDS             4259..5281
                     /locus_tag="VXD01_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV0601994.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5298..6167
                     /gene="licA"
                     /locus_tag="VXD01_001633"
     CDS             5298..6167
                     /gene="licA"
                     /locus_tag="VXD01_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV0601995.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            6157..7035
                     /locus_tag="VXD01_001634"
     CDS             6157..7035
                     /locus_tag="VXD01_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV0601996.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7047..7736
                     /locus_tag="VXD01_001635"
     CDS             7047..7736
                     /locus_tag="VXD01_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV0601997.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7842..8690
                     /gene="dprA"
                     /locus_tag="VXD01_001636"
     CDS             7842..8690
                     /gene="dprA"
                     /locus_tag="VXD01_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV0601998.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9539..10582
                     /locus_tag="VXD01_001637"
     CDS             9539..10582
                     /locus_tag="VXD01_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV0601999.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            10749..12836
                     /gene="topA"
                     /locus_tag="VXD01_001638"
     CDS             10749..12836
                     /gene="topA"
                     /locus_tag="VXD01_001638"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV0602000.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEVASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            12942..13301
                     /locus_tag="VXD01_001639"
     CDS             12942..13301
                     /locus_tag="VXD01_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV0602001.1"
                     /translation="MRLIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYILMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13394..14026
                     /locus_tag="VXD01_001640"
     CDS             13394..14026
                     /locus_tag="VXD01_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV0602002.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            14070..14726
                     /locus_tag="VXD01_001641"
     CDS             14070..14726
                     /locus_tag="VXD01_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV0602003.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMTGSFVASVREACLEILYQIRKTCFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14745..15377
                     /locus_tag="VXD01_001642"
     CDS             14745..15377
                     /locus_tag="VXD01_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV0602004.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVFRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            15405..15828
                     /locus_tag="VXD01_001643"
                     /pseudo
     CDS             15405..15828
                     /locus_tag="VXD01_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
     gene            15840..16877
                     /gene="leuB"
                     /locus_tag="VXD01_001644"
     CDS             15840..16877
                     /gene="leuB"
                     /locus_tag="VXD01_001644"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV0602005.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAWPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNIYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILSVVMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            16874..17143
                     /locus_tag="VXD01_001645"
     CDS             16874..17143
                     /locus_tag="VXD01_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV0602006.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            17147..17506
                     /locus_tag="VXD01_001646"
     CDS             17147..17506
                     /locus_tag="VXD01_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV0602007.1"
                     /translation="MAGSSREHAAWALANYGFKVVIAGTFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDHVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17725..17868
                     /locus_tag="VXD01_001647"
     CDS             17725..17868
                     /locus_tag="VXD01_001647"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602008.1"
                     /translation="MTSDKAGLERKFAAKERKRNKPGVVLCGSMDELCALAQLNPEIE
                     AFY"
     gene            17887..18141
                     /locus_tag="VXD01_001648"
     CDS             17887..18141
                     /locus_tag="VXD01_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602009.1"
                     /translation="MLLGCILPWKPEAFEKLKAYGDGREELMTDVRGTSCFVIKFGKA
                     GEQLAAKLWEEGKMVYASYASMTKRLKLAMRARCNGVYGR"
     gene            18131..18292
                     /locus_tag="VXD01_001649"
     CDS             18131..18292
                     /locus_tag="VXD01_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602010.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNS
                     WDYRQREYY"
BASE COUNT         5779 a         3156 c         3909 g         5605 t
ORIGIN      
        1 gatatgatgc gttttattgt gggaatatgt atttcatttt ctactaaaat tatgtttttg
       61 aataacctct atcttagtag tttgtataat acccctcaat cagtttttgc gataagcttt
      121 aatgctatga ctataccact cttgcatttc ttttgatggt ggtgtcatat aatcgccata
      181 catctgggtt aaaaattggt catatttttt gggaacaggc aacatacggc cctcaaactc
      241 agttaaaatc agttctttaa aggtatcaac tgggaagatt tctttcatcc cttccttacc
      301 gatcccaact cctccttcat attgaggagt gttggttaca gcatttttga ctagttgatc
      361 aattttcttg taaaagtagc gaggattgac aaatcggaga gcgtaccagc tacataatct
      421 aagaaaatct tttagtttgc tatcaccgtg aactgctcgt gattttttga tataagctag
      481 ttgacgaaga gccacatact tatagctctt gtcgacaatg ctcaagtctg taaatcgatc
      541 aattgggaag acatcgatga aaaggctggt atcatgacgc ttgtacttaa catggtcttc
      601 tataacagta gaagtgtcca aaatcgatgc gaaattatgg aagtaccaag aagatgtatc
      661 gtaggaaaga accttgtagc gagggtgatt ttcttcttca ataatcttca gtaaacgctc
      721 ataatcctca cgataaaggg aaatatcaat atcatcatcc caaggaatca tacctttgtg
      781 gcggatggct ccaagcatgg ttccataact gagaaaataa ggaatatcat atttcttaca
      841 agtctcatca atatagtcca gcagggctag ttgaatttct ttaatttctt ttttttctaa
      901 atattgcatc ctaatcctcc aatttataag cgtgaaattc atgactgtag aagcgttttt
      961 cttctggtgg tagggtcata taatctccat aaaattgtgt caaaatagta tcaaattttt
     1021 caggtgcagg aaggcttaaa ttctcaaagg gtaaatcgat tgttttatca aaggtaccac
     1081 ttgggaagac ttccttttcc ttaaattttg aagggataaa agccatatat tgcccatttt
     1141 cacgactata tttttgaatt tctttctcga ttttatttgc aaaataacga ggagaaaccg
     1201 gtcgaaggag taaccagaag gctgttcgta tccaatcttt taaaaggcta tccttataga
     1261 caatattttt atgtttactg aaagacagca gtttgaagct ttccagttta taacaagtat
     1321 caatgacctt aggatcatca aagcgatcta tagggaaaat atcgataaag ataccagact
     1381 cataggtttt tgtatttcga gtatcaataa ttttagtcgt actgtcggtt atcttgataa
     1441 agttgttaaa gtagttctta tcagtttcta aggataggag cttatacttg cttttttcct
     1501 tttgaaaaat gttaataaat cgttggtagt cttctctagg catggataaa tcaatatcgt
     1561 cgtcccaagg gataaagccc tcatgtcgaa ccgccccaat cagagtaccg tagttaataa
     1621 tatagttgat attgtgcttt ttacagagag tatcaatata atccaaaatt tctaattcaa
     1681 tttgtttggc atcttcaacg gttagttgtt tcattttaaa ctcctatgat tttttaaatt
     1741 tattttttaa ggctaggaca tggtttaaaa attcatagaa aatgctatct tttgtgaaga
     1801 caagtagact aatataagag atagctgata gcaagacaat caaaccagta ttaatcaaaa
     1861 atggcaaatt aatgaccata tccacaggat acacgaaatt aatcaggaaa taaattgcta
     1921 caaaggaaag tgaaaagaga gagtatcgaa cagtatagct aaagatatgt cccaagtgga
     1981 tgagttgttt tctatggatg aaaatgatat agaaaacaag tagagaagtc tctgataaca
     2041 tagttgtcag taagtagtat tcaggagcca cgatatggtt gaaaaagagg agactattca
     2101 agcccaaatt gagtagccca gcaaagactg tatagactgt gatacgtttt tcatagccat
     2161 tggtaaagag aatttgggaa ccaagaatgg tatctaaggc caggataatc gtacgaaaag
     2221 cgaagagaga ggtcaagatg ccgcctccga tatatttttc actaccgtaa agtaggatgg
     2281 catttggtcc taaaaccatg agtccaaaac tcagtggaat gataaagaag ttaaagattc
     2341 gactacctct attaaccaga gaaacatagg cttctttgtc tcctttcccc agatagtaac
     2401 tgagacgagg cacactcact ccaattgcac ctgttacaac cccagctata acggtcacaa
     2461 ttcgctgagc tatggtatag taactaacgt tgacatcaat ccctgtttta acgaggaaga
     2521 ggcgatctaa aaaagtgaag agcatattgg cattggcaaa gactaacatg gctgtcagag
     2581 ggagaaagag tggtttaaaa tcacttaggt gaatcttaac aagtttgatg tctcttttaa
     2641 tccaaaaata actaatcagg tagttaatca gcgtcgataa actcatcaca agtgtataga
     2701 caacaatatc gtgttcattt ttaacaaata agaaaataga gaccagcatc aggatacgga
     2761 tgaaggcagt tttgtaaaag agaaaactgt aattttccag agcttcattg acccattcga
     2821 ttgaaaaaat ctgggcaatg agttgaatcc ccataacaag gtagaccttt ttgacgattg
     2881 gattatcaat aaagaagaga ggataggcta ggatatagac agcagtggtc aaaatcgtac
     2941 aagcgatgca caaataaaaa agactagaaa aggttctgtt aagatctttt ttgttatcct
     3001 tgacattact gatagccctt aaaccgtagt tatagacacc ataagttgca aagggcaaga
     3061 aaaatgacaa aatagtgtcg actgagttga agtaaccata gtcagttcgg tccaagacac
     3121 gcgcgacata ggttccagtt aggatgggaa aaataatatt caagacacga attcccatgt
     3181 aagatagagc atttaatttt atacttttca ttcaatttac ctcgtttttc attatatcat
     3241 aaagttagct aataagaaat gaagggcagt aagtcaagta atcactttga agtttcaaat
     3301 cttaagtttt aagttttctt taaggaaagt atattattct gaaggactct aaaatttcgc
     3361 agccatttat tagtaattgc tacagaattc ctagtcatta ctagaaatgg actagtttct
     3421 ttgaataata gaactgcata attctcctat tctagaaggg gaggaccagt atttctttta
     3481 tgataggact agattgtggt ataatagaga gaataagttt ttttagtaag acaaaggaga
     3541 aaatagatga tttatgcagg aattcttgcc ggtggaactg gcacacgcat ggggatcagt
     3601 aacttgccaa aacaattttt agagctaggt gatcgaccta ttttgattca tacaattgaa
     3661 aaatttgtct tggagccaag tattgaaaaa attgtagttg gtgttcatgg agactgggtt
     3721 tctcatgcag aagatcttgt agataaatat cttcctcttt ataaggaacg tatcatcatt
     3781 acaaagggtg gtgctgaccg caatacaagt attaagaaaa tcattgaagc cattgatgct
     3841 tatcgtccgc ttactccaga ggatatcgtt gttacccacg attctgttcg tccatttatt
     3901 acacttcgca tgattcagga caatatccaa cttgcccaaa atcatgacgc agtggacaca
     3961 gtggtagaag cagttgatac tatcgttgaa agtaccaatg gtcaatttat tacagatatt
     4021 ccaaatcgtg ctcaccttta tcaaggacaa acacctcaaa cattccgttg caaggacttc
     4081 gtggaccttt atggatctct ttctgatgaa gagaaggaaa tcttgacaga tgcatgtaaa
     4141 atctttgtga tcaaaggaaa agatgtggcc ttggccaaag gtgaatactc aaatctgaag
     4201 attacaaccg taacagattt gaagattgca aaaagtatga ttgagaaaga ctagtaaaat
     4261 gattaatcaa atttatcaac taactaagcc taagtttatc aatgtcaaat atcaggaaga
     4321 ggctattgac caagagaatc atatccttat ccgtcccaac tacatggctg tctgtcatgc
     4381 ggatcagcgt tactatcagg gaaaacgtga tcccaagatt ttgaataaaa agcttccaat
     4441 ggcaatgatt cacgagtcat gtggaaccgt catttctgac ccgaccggaa cctacgaggt
     4501 tggtcaaaaa gttgtcatga ttcccaatca gtctcctatg cagagtgatg aagaattcta
     4561 tgaaaactac atgacaggga cccatttctt gtctagtgga tttgatggct ttatgagaga
     4621 gtttgtttct ctccctaaag atcgtgtggt ggcttatgat gctattgaag atacggttgc
     4681 agccattaca gagtttgtca gtgtgggcat gcacgctatg aatcgtctat tgactcttgc
     4741 tcatagcaag cgggagcgga tcgccgttat tggagatgga agtttagctt ttgtggttgc
     4801 caatattatc aactatactt tgccagaatc agagattgtg gttattggtc gtcattggga
     4861 aaagttggaa ctcttctcat ttgccaaaga atgctatatt acggataata ttcctgaaga
     4921 gttggccttt gaccatgctt ttgaatgttg tggtggtgat ggtactggac cagctattaa
     4981 tgacttgatt cgctacattc gtcctcaggg aacgattctc atgatgggag ttagcgaata
     5041 taaagtcaat ctcaatactc gcgatgcctt agaaaagggc ttgattttgg ttgggtcatc
     5101 tcgttctggt cgcattgatt ttaaaaatgc tatccaaatg atggaagtca agaaatttgc
     5161 caatcgtctt aaaaatatcc tttatctaga agaacctgta agagaaatta aagatattca
     5221 tcgtgtcttt gcaaccgatt taaacacagc ctttaaaaca gtgtttaagt gggaagtata
     5281 agtactggag gttaattgtg gagaaaatca ttaaagaaaa aatttcttcc ttacttagtc
     5341 aagaagagga agtcctcagt gttgaacaac tgggtggaat gaccaatcaa aactatttgg
     5401 ccaaaacaac aaataagcaa tacattgtta aattctttgg taaagggaca gaaaagctta
     5461 tcaatcgaca agatgaaaag tacaatcttg aactactaaa ggatttaggc ttagatgtaa
     5521 aaaattatct ttttgatatt gaagctggta tcaaagtaaa tgagtatatc gaatctgcga
     5581 ttacgcttga ttcaacgtca atcaagacca agttcgacaa aattgctcca atattacaaa
     5641 ctattcatac gtctgctaag gaattaagag gagaatttgc tccttttgaa gaaatcaaaa
     5701 aatacgaatc cttgattgaa gaacaaattc cttatgccaa ctatgaatct gttagaaatg
     5761 cagtcttctc cttagagaaa agactggctg acttaggtgt tgacagaaaa tcttgtcata
     5821 tcgatttggt gcctgaaaac tttatcgaat cacctcaagg acgactttat ttgattgact
     5881 gggaatattc atcaatgaat gatccaatgt gggatttggc tgccctcttt ttagagtctg
     5941 aattcacttc ccaagaggaa gaaactttct tatctcacta tgagagtgac caaacaccgg
     6001 tttctcatga aaagattgct atttataaaa ttttacaaga tactatttgg agtctatgga
     6061 ctgtctataa ggaagagcaa ggtgaagatt ttggtgacta tggtgtgaat cgttaccaaa
     6121 gagctgttaa aggtttggct tcttatggag gttcagatga aaagtaaaaa cggagttcct
     6181 tttggccttc tctcaggtat tttctggggc ttgggtctaa cggttagtgc ttatatcttt
     6241 tcgattttta cagatttgtc accctttgtg gtggctgcag ctcatgattt tttgagcatc
     6301 tttatcttac tagcttttct cttggtaaaa gaagggaaag ttcgcctctc aattttctta
     6361 aatattcgca atgtcagtgt tatcatcgga gccttgctag caggccctat cggtatgcag
     6421 gccaatcttt atgcagttaa gtatatcgga agttctttag cttcatctgt atcggctatt
     6481 taccctgcga tttcagttct attggctttc ttctttttga agcacaagat ttcgaaaaat
     6541 actgtatttg ggattgtctt gattattgga gggattattg cccagaccta taaggttgaa
     6601 caggttaatt ccttctacat tgggattctc tgtgctttgg tttgtgctat tgcatgggga
     6661 agtgagagtg ttcttagctc ctttgctatg gaaagtgaac tgagtgaaat cgaagccctc
     6721 ttaatccgtc aagtgacttc gttcttgtcc tatcttgtga ttgtgctctt ctctcatcag
     6781 tcatttactg cagtagccaa tggacaattg ctaggtctca tgattgtttt tgcagccttt
     6841 gatatgattt cctacttggc ttattatatc gctatcaatc gcttgcaacc agccaaggct
     6901 acaggcttga acgtgagcta tgtagtatgg acggtcttgt ttgcagttgt ttttttgggt
     6961 gcaccgctag atatgctgac cattatgacg tcacttgtcg tcattgctgg agtttatatt
     7021 attattaaag aataaaggag attcgtgtga aagccattat cttagcagcg ggattgggaa
     7081 ctcgcttgcg tcctatgact gaaaataccc ctaaagcctt ggttcaggtt aatcaaaaac
     7141 ctttgattga ataccaaatt gagtttctca aagaaaaagg aatcaatgac atcatcatca
     7201 ttgttggtta tcttaaagaa caattcgatt acttaaaaga aaaatacggt gttcgcctcg
     7261 ttttcaatga taaatacgct gactacaata acttttactc tctctatctt gtaaaagaag
     7321 aattggccaa cagctatgtt attgatgctg acaattatct ctttaaaaat atgttccgca
     7381 atgatttgac acgttcgact tattttagtg tttatcgtga agattgtacc aacgaatggt
     7441 tcttggtcta tggagatgac tacaaggttc aagacattat tgttgatagc aaggcaggtc
     7501 gcatccttag tggtgtatcc ttctgggatg ctccaactgc agaaaagatt gtcagcttta
     7561 tcgacaaggc ttatgcaagt ggtgaatttg ttgatctcta ttgggacaat atggttaagg
     7621 ataatatcaa agagctagat gtctatgttg aagaattaga aggcaatagc atttatgaga
     7681 tcgatagtgt ccaagactat cgtaaattag aagaaattct taaaaacgaa aattaaagat
     7741 tccaacatct ggcaaaatag tcggatgttt tttgattttt tacgaacttt tacgaacttt
     7801 tacgaataga tagatgagta gaaaaagaaa tggagttatt tatgaaaatc acaaactatg
     7861 aaatctataa gttaaaaaaa tcaggtttga ccaatcaaca gattttgaaa gtgctagaat
     7921 acggtgaaaa tgttgatcag gagcttttgt tgggtgatat tgcagatata tcaggttgcc
     7981 gtaatccagc cgtttttatg gaacgttatt ttcagataga cgatgcgcat ttgtcgaaag
     8041 agtttcaaaa atttccatct ttctctattt tagatgactg ttatccttgg gatttgagtg
     8101 aaatatatga tgcgcctgta cttttatttt acaagggaaa tcttgacctc ctgaaattcc
     8161 cgaaggtagc ggtcgtgggc agtcgtgctt gtagcaaaca gggagctaag tcagttgaaa
     8221 aagtcattca aggcttggaa aatgaactgg ttattgtcag tggtctggcc aagggcattg
     8281 acacagcagc tcatatggca gctcttcaga atggcggaaa aaccattgca gtgattggaa
     8341 caggactgga tgtgttttat cctaaagcca ataaacgctt gcaagactac atcggcaatg
     8401 accatctggt tctaagtgaa tatggacctg gcgaacaacc tctgaaattt cattttcctg
     8461 cccgtaatcg catcattgct ggactttgtc gtggtgtgat tgtagcagag gctaagatgc
     8521 gttcaggtag tctcattacg tgtgagcgag caatggaaga aggacgcgat gtctttgcta
     8581 ttcctggtag cattttagat ggactatcag acggttgcca tcatttgatt caagaaggag
     8641 caaaattggt caccagtggg caagatgttc ttgcggaatt tgaattttaa aaatgaccta
     8701 agctagaatt ctaagaaaaa atcaatttta agagaaaatg aacccaacat ttccataata
     8761 aaacgcatat tagcaagttt ttaacacttg ataatatgcg ttttttctaa gtggattagt
     8821 agagtagagg atttttctca tataatactc ttcgaaaatc tcttcaaact acgtcagctt
     8881 ccatctgcaa cctcaaaaca gtattttgag ctgacttcgt cagtcttatc tacaacctca
     8941 aagcagtgct ttgattttca ttgagtataa gggaaagtat agtgaattga aataagatgt
     9001 gaacaactct atcaggaaag tcaaattaat ttatagaaat attttagcag ccaaggtgta
     9061 ctgttataga ttcaatacac tataatttag tgtaattgag aaaggagaaa tgattgtgat
     9121 tgatgttggc taggttatgt tcaatgattc ctaccgtctc aaatcttgtc agtaaggaaa
     9181 aataaattct tcaaaagtag agattacaag gcttgtttaa gaaagaattc aaagaccttg
     9241 acaaataaaa ataaaatggt tattataaga aatggtctaa aatagatgat gatacttttc
     9301 gaaaatcttt ttacgtcagc tcagctttgc cttgctgtgt tttgagcaag ctacggttag
     9361 cttccgagtt tgattttcat ttactagaaa tgaaactgat gagagatatc agtagacatt
     9421 tgagtcagga tattatggaa aatgataaaa agagcttgtg agattggcat atcagactac
     9481 taaagtattg agtttgttag gattttagcg actagttagc tgggaaagga agatatttgt
     9541 gacaaataat aaactgtatt cgttgataga atttagaaat aaaatatatg aagaattaga
     9601 actttccaga agtgatttag cgattttact atgtgccatg cttatcgcct ctatcggatt
     9661 aaatatggat tcgactcccg tgattattgg agccatgtta atctctcctt tgatgacacc
     9721 tattctggga gtggggctct ctctagctat atttgatttt aaattgttaa gaaaatcttt
     9781 taaaatatta gctattcaaa ttcttgccag tctaatagct tcaacacttt atttttatct
     9841 ttctcccatt tcgtatgcta gttcggagat tgttgctaga acctctccga ctatttggga
     9901 tgttctcatt gcttttgtag gagggatagc aggtattatt ggtgctagga aaaaagagac
     9961 caataatatt gttcctggtg ttgctattgc aaccgccttg atgcctcctc tttgtacagt
    10021 aggttatgct attgcttctg ctaatctaaa atttatcata ggctcctctt acctattcct
    10081 catcaattgt agctttattg tcattgcgac ttatataggt gttaggttga tgatggttaa
    10141 gaaacattat tttaaagata atgaagaaga ctctaaaatg cgtaggattt tgcttctagt
    10201 tgctgttttg ctgatgattc cgagtttcat ctctgcaacg actttagtga gagaaacgtt
    10261 gaaaaaagag tcccttaaga aatttatatc agagcagttt caggggtata atattttgaa
    10321 aaaaacctat tctaaaaaga ctcataccct aaagctaacc atttcaggaa attatttgac
    10381 agaagaagaa ctcgatatga tttcaagtaa gagaggtgac tatggtttaa gtgatgtttc
    10441 tgttcaagtt tcacaattgt ctgattcaga acaacttagt aaggaagagc tggtggagta
    10501 tttcttccag tatatcaagg ataaggaagc aaaagaaaag gaaaaagcta ataagtttta
    10561 tacagagtct gaggagcaat aatttcttga gaatagctgg tttttctcgt gagtcttcta
    10621 tgtatatcaa aggaagactg aggttttaag tataaaactt ttcttctatt atagtagcta
    10681 agtcttgaca gggttcaaaa aatggtttac actttataaa gtttattact ttgaaaaggt
    10741 gtgatactgt ggctacggca acaaaaaaga aaaaatcaac agttaaaaaa aatctagtca
    10801 tcgtggagtc gcctgctaag gccaagacga ttgaaaaata tctaggcaga aactacaagg
    10861 ttttagccag tgtcgggcat atccgtgatt tgaagaaatc cagtatgtcc gtcgatattg
    10921 aaaataatta tgaaccgcaa tatattaata tccgaggaaa aggccctctt atcaatgact
    10981 tgaaaaaaga agctaaaaaa gctaataaag tttttctcgc gagtgacccg gaccgtgaag
    11041 gagaagcgat ttcttggcat ttggcccata ttctcaactt ggatgaaaat gatgccaacc
    11101 gtgtggtctt caatgaaatc accaaggatg cagtcaaaaa tgcttttaaa gaacctcgta
    11161 agatcgatat ggacttggtc gatgcccaac aagctcgtcg gatcttggac cgcttggtag
    11221 ggtattcgat ttcgcctatt ttgtggaaga aggtcaagaa gggcttgtca gcaggtcgcg
    11281 ttcagtccat tgcccttaaa ctcatcattg accgtgaaaa tgaaatcaat gccttccagc
    11341 cagaagaata ctggacagtt gatgctgtct ttaaaaaggg aaccaaacaa tttcatgctt
    11401 ccttctatgg agtagatggt aaaaagatga aactgaccag caatgacgaa gtcaaggaag
    11461 tcttgtctcg tctgacgagt aaagactttt cagtagatca ggtggataag aaagagcgca
    11521 agcgcaatgc tcctttaccc tataccactt catctatgca gatggatgct gccaataaaa
    11581 tcaatttccg tactcgaaaa accatgatgg ttgcccaaca gctctatgaa ggaattaata
    11641 tcggttctgg tgttcaaggt ttgattacct atatgcgtac cgattcgact cgtatcagtc
    11701 ctgtagcgca aaatgaggtg gcaagcttca ttacggatcg ttttggtagt aagtattcta
    11761 agcacggtag caaggtcaaa aacgcatcag gtgctcagga tgcccatgag gctattcgtc
    11821 cgtcaagtgt ctttaataca ccagaaagca tcgctaagta tctggacaag gatcagctca
    11881 agctatatac ccttatctgg aatcgttttg tggctagcca gatgacagcg gccgtttttg
    11941 ataccatggc tgttaaattg tctcaaaaag gggttcaatt tgctgccaat ggtagtcagg
    12001 ttaagtttga tggttatctt gccatttata atgattctga caagaataag atgttaccgg
    12061 acatggttgt tggagatgtg gtcaaacagg tcaatagcaa accagagcaa catttcaccc
    12121 aaccgcctgc ccgttattct gaagcaacac tgattaaaac cttagaggaa aatggggttg
    12181 gacgtccatc aacctacgcg ccaaccattg aaaccattca gaaacgttat tatgttcgcc
    12241 tggcagccaa acgttttgaa ccgacagagt tgggagaaat tgtcaataag ctcatcgttg
    12301 aatatttccc agatatcgta aacgtgacct tcacagctga aatggaaggt aaactggatg
    12361 atgtcgaagt tggaaaagag cagtggcgac gggtcattga tgccttttac aaaccattct
    12421 ctaaagaagt tgccaaggct gaagaagaaa tggaaaaaat ccagattaag gatgaaccag
    12481 ctggatttga ctgtgaagtg tgtggcagtc caatggtcat taaacttggt cgttttggta
    12541 aattctacgc ttgtagcaat ttcccagatt gccgtcatac ccaagcaatc gtgaaagaga
    12601 ttggtgttga gtgtccaagc tgtcatcagg gacaaattat tgagcgaaaa accaagcgta
    12661 atcgcctctt ctatggttgc aatcgctatc cagaatgtga atttacctct tgggacaagc
    12721 ctgttggtcg tgactgtcca aaatgtggca acttcctcat ggagaaaaaa gtccgtggtg
    12781 gtggcaagca ggttgtttgt agcaaaggcg actacgagga agaaaagatt aaataagagg
    12841 aggggcccga aagtaaattt caggctcctt ttggttagaa cttgacaaaa tacatcattt
    12901 tatgcgaaac tagaagaaga ttattttaac taggagaagt tatgcgtctt atctatctga
    12961 taattggttt tttatcactg accttggcta ttgttggggt tgttttaccc ttgttgccga
    13021 caacgccttt ccttttgttg tctattgctt gtttctccag aagttccaag cgtttcgaag
    13081 actggcttta tcataccaag ctctatcaaa catatgtagc tgattttcgc gagactaagt
    13141 ctattacgcg tgaacgaaag aaaaaaatca tcgtatccat ttacattttg atggggattt
    13201 ctatttattt tgcccctctc ttaccagtca aaatcggtct gggtgctttg accatcttta
    13261 tcacttatta tcttttcaag gtcattccag acaaagaata gttaaaacag tagttatttg
    13321 ccttgataaa attgaaagca tattcataac aatatgatat aataaatttg aagtaatatt
    13381 caaggagaat caaatgattt acgaattttg tgctgaaaat gtgactttac ttgaaaaagc
    13441 gatgcaggct ggagctcgtc ggattgaact ctgtgataat ctagcagttg gtgggacaac
    13501 acccagctat ggagtgacta aggcagcggt tgaactggca gctaactacg atacaaccat
    13561 catgaccatg attcggccac gtggtggtga ctttgtctat aatgacctag aaattgctat
    13621 catgctagaa gacattcgtt tgactgctca ggctggaagt caaggggttg tatttggagc
    13681 tttaactgct gataaaaagt tggataagcc taatctggaa aagttaattg ctgcatcaaa
    13741 aggaatggaa attgtctttc acatggcctt tgatgaacta agtgatgaag atcaaccgga
    13801 agctattgac tggctcagtc aagccggtgt cactcgtatc ctaactcgtg ctggtgtgtc
    13861 tggcgactcc ttagaaaaac gttttgttca ctatcacaga attttggagt acgctaaagg
    13921 taaaattgaa attctaccag gtggggggat tgaccttgac aaccgtcaaa cctttatcga
    13981 ccaggtgggg gtaacacaat tgcatggtac taaggttgtt ttttaaaaaa tagaaaggaa
    14041 ctgctagctt tgggtagcag ttttcactta tgtttgaaat ttttaaatcc tatcaattta
    14101 atcaagaaaa ggctcatgat tatggtttta tagaaaatag cgaagtctgg acatatagtt
    14161 gccagatttt gcaaggtgac tttgtcatga ctgtgtccat cactgctgat aatgtgaact
    14221 ttcaagtctt tgaccaagag actggtgacc tctatcctca cgttcatatg gaaagtatga
    14281 caggaagttt tgttgcaagt gtccgtgagg cttgtttgga gattctttac cagatacgga
    14341 agacttgttt tgatgtgcaa gattttatct gtcatcagac taagcgtatc atgactcaag
    14401 ttcaggaaaa gtatggaaac cagttggagt atctgtggga aaaatcgcct gatacagctg
    14461 tattgcgcca tgaaggcaat caaaagtggt atgccgtctt gatgaaaatc tcttggaata
    14521 agctggaaaa gggcagagaa ggacaagtgg aagcagtcaa cctcaagcat gaccaagtag
    14581 ctaatttgct ttcacaaaag gggatttatc cagccttcca tatgagcaag cgctactgga
    14641 ttagtgtgtc ccttgatgat actttatcag atgaagaagt actggaattg atagaaaaaa
    14701 gttggaactt aacctctaaa aaatgaaata ttttaataat tttcatgaac tttcaattag
    14761 ctaaatattc tttactgaag aaattttcag aaaatatagg atttaccaca ctagaggaat
    14821 atggtgccat cttcaaatac ctgattgaga atgtcaagac ggatcgtcag atcatctatt
    14881 cgcctcactg tcatgatgac ctcggaatgg cagtggcaaa tagccttgct gctgtcaaga
    14941 atggtgcagg acgtgttgaa gggactatca atggtattag ggagcgagct gaaaatgctg
    15001 ctttggaaga aattgcagtg gctctcaata ttcgccaaga ttactaccaa gtagaaacca
    15061 gtattgtcct aaatgagacc atcaatacgt cagaaatggt ttttcgcttc tctggtattc
    15121 cagttcctaa aaacaaagcc gtcgttggtg gcaatacctt ctcccacgaa tctggtattc
    15181 accaagatgg agtccttaaa aatcctctca cttatgagat catcacacct gaattggttg
    15241 gtgttaagat tccgcttgga aaattatctg gtcgccatgc ttttgttgag aaactgagag
    15301 aattggccct agattttaca gaagaggata tcaaaccact ctttgctaag ttcaaggcac
    15361 tggccgataa gaagtaagaa atcacagatg cagatactcg agctttggta gctggaacca
    15421 tggttgaaaa tccagaaggc ttccactttg atgatttaca acttcaaact catgcagata
    15481 atgacattga agctagccaa tatggatggt gagaaagtcg aatttaatgc gacagggcaa
    15541 ggttccgttg aagcaatctt taatgctatc gataagttct ttaaccaatc tgttcgtttg
    15601 gtgtcctaca ctatcgatgc ggtaacagat ggaatcgata cccaggatcg ggttttggtc
    15661 actgttgaaa acagagatac agaaaccatc tttaatgcag cagggcttga ttttgatgtg
    15721 ttgaaggctt ctgctattgt ctatataaac gctaatacct ttgttcaaaa agagaatgca
    15781 ggtgagatgg gacgcagtgt ttcttaccac gatatgccta gtgtgtaaag gagaaggcta
    15841 tggcaaagaa aatagtagct ctagcaggag acggaattgg cccagaaatc atggaggttg
    15901 gtttagaagt tctggaggct ctagctgaaa aaacaggttt tgactatgag attgacagac
    15961 gaccgttcgg aggtgcagat attgatgcag catggcctcc cttacctgat gaaaccctta
    16021 aggcaagtag ggaagcagat gctatcctac tagcagctat cggtagtcct cagtatgatg
    16081 gagcagtggt tcgccctgaa caaggcctga tggctctccg taaggaactc aatatttacg
    16141 ctaatattcg tcctgtaaaa atctttgaca gtctcaagca tttgtcacca ctcaaactgg
    16201 aacgaattgc tggtgtagac tttgtcgtgg tgcgtgaatt gacaggcggg atttactttg
    16261 gagatcatat tcttgaagag cgcaatgcgc gtgatatcaa cgactatagc tatgaggaag
    16321 tggagcggat tattcgcaaa gcctttgaaa ttgcaagaaa tcgcagaaaa atcgttacta
    16381 gtatcgataa gcaaaatgtt ctagcgacct caaaactctg gcggaaggta gctgaggaag
    16441 tcgcacagga tttcccagat gtaaccttgg aacatcagct ggtagactca gctgctatgc
    16501 ttatgattac caatcctgct aagtttgatg ttattgtaac ggagaatctt tttggagata
    16561 ttttatctga tgaatcaagc gtcttatctg gtacacttgg ggttatgcca tcagccagtc
    16621 attctgaaaa tggaccaagt ctctatgaac ctattcacgg ttcagcacct gatattgcag
    16681 gtcaaggaat tgccaatcct atttccatga ttttatcagt tgtcatgatg ttgagagata
    16741 gtttcggacg ttatgaggat gcagagcgta tcaaacgtgc tgttgagaca agtctggcgg
    16801 caggaatttt aacgagagat ataggaggtc aggcttcaac aaaggaaatg acggaagcta
    16861 ttattgcaag gttatgaagt tagacgaaaa aattactcta gtccttttga tttggaatgt
    16921 catcattttc ttgatttatg gcattgacaa attcaaggca agaagaagag cttggcgcat
    16981 ccaagagaaa atcttactca ttttagccct tacttgtggt ggttttgggg cctggttagc
    17041 tggaatcact tttcaccaca agactcgaaa atggtacttt aaaacagttt ggtttcttgg
    17101 gatggtgact acactagtag ccttatattt tatttggagg taatggatgg cagggtcttc
    17161 gagggaacac gctgcttggg ctctagcgaa ctatggtttt aaggtcgtga ttgcaggaac
    17221 tttcggtgac attcattaca ataatgaact caataatggc atgttgccaa tcgttcagcc
    17281 tagagaggtt agagagaaac tagcccagct aaaaccaacc gaccatgtaa ctgtggactt
    17341 ggaacaacaa aaaatcatct caccagttga agaattcacc ttcgagatag atagcgagtg
    17401 gaaacataaa ctcctaaata gtttggatga tatcggtatt accttgcagt atgaagagtt
    17461 gattgctgct tatgaaaaac aacgaccagc ctactggcag gattagaaaa aatagaaaag
    17521 gaaatatagt aaactgaaat aagatgtaaa caaatgaatt agagcttaac atccatttcc
    17581 agcaattttt tagaaactac agtggactat tctggattca acacattata aaattatgac
    17641 aaaacacatt cacaagaagg ctacgacatt ttaaaaggtg agggtggatg tatcgtttgc
    17701 cctactaaag ttggttacat tatcatgacc agtgataagg caggacttga gcgtaagttc
    17761 gcagccaaag aacgtaagcg taacaaacca ggtgttgttc tctgcggtag catggatgaa
    17821 ctttgcgctt tagcgcaact caacccagaa attgaagcat tctactaaaa acattgggat
    17881 gaagatattc ttcttggttg tatccttcct tggaaaccag aagcctttga aaaactcaaa
    17941 gcatacgggg atggccgtga agaacttatg actgatgtac gtggtactag ctgttttgtt
    18001 atcaagtttg gaaaagcagg tgaacaattg gctgccaagc tttgggaaga aggtaaaatg
    18061 gtctacgcct catatgcttc aatgacaaaa cgattgaaac tcgctatgag agcaaggtgt
    18121 aatggtgtct atggtcgata aggacggcaa actcatccca gaacaaggag gagcacgttc
    18181 aacctcacca gcaccagttg tgatccgtaa agggcttgac attgataaaa tcatgatgca
    18241 cctgtcagac acctttaact catgggatta ccgtcagaga gagtattatt aggataaaaa
    18301 agaagtctag tgttatgaga tattaaagct cctaacactg ggctttttgt ttagaatttc
    18361 ttttcttttt ctataggata tggtattcta tgtagaaaat atatgttaat aagtaatgcc
    18421 aatatttaaa catcattagt aaaaggagt
//
LOCUS       DAVLDI010000046        18294 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLDI010000046 DAVLDI010000000
VERSION     DAVLDI010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18294
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.046"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            87..5390
                     /locus_tag="VXD01_001650"
     CDS             87..5390
                     /locus_tag="VXD01_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV0602011.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPTDLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPRAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASVTVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDLYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FESLDAPAQPGEGLENAFDGNVSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(5556..7715)
                     /locus_tag="VXD01_001651"
     CDS             complement(5556..7715)
                     /locus_tag="VXD01_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HEV0602012.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(7712..8308)
                     /gene="recU"
                     /locus_tag="VXD01_001652"
     CDS             complement(7712..8308)
                     /gene="recU"
                     /locus_tag="VXD01_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV0602013.1"
                     /translation="MVNYPHKVSSQKRQKSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            8374..8901
                     /locus_tag="VXD01_001653"
     CDS             8374..8901
                     /locus_tag="VXD01_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV0602014.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENEIKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            8971..9300
                     /gene="gpsB"
                     /locus_tag="VXD01_001654"
     CDS             8971..9300
                     /gene="gpsB"
                     /locus_tag="VXD01_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV0602015.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            9321..9701
                     /gene="rnpB"
                     /locus_tag="VXD01_001655"
     ncRNA           9321..9701
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VXD01_001655"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9786..10943
                     /locus_tag="VXD01_001656"
     CDS             9786..10943
                     /locus_tag="VXD01_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV0602016.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            10956..12326
                     /gene="mapZ"
                     /locus_tag="VXD01_001657"
     CDS             10956..12326
                     /gene="mapZ"
                     /locus_tag="VXD01_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV0602017.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEELVETQSLDDLIQEMREAVEESEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQASSNTTS
                     EPKPSSSNETRSSRSEVNMGLSSEGVAVQRSASRVAYNQSAIDDSNNSAWDFADGVLE
                     QILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGYFVGNGAGH
                     ADDLDY"
     gene            12402..13826
                     /gene="gndA"
                     /locus_tag="VXD01_001658"
     CDS             12402..13826
                     /gene="gndA"
                     /locus_tag="VXD01_001658"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV0602018.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            13838..14527
                     /locus_tag="VXD01_001659"
     CDS             13838..14527
                     /locus_tag="VXD01_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0602019.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGIGYTMQE"
     gene            14625..15644
                     /gene="cbpC"
                     /locus_tag="VXD01_001660"
     CDS             14625..15644
                     /gene="cbpC"
                     /locus_tag="VXD01_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV0602020.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIM
                     QTGWQYLGNKWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNASNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(15762..16994)
                     /locus_tag="VXD01_001661"
     CDS             complement(15762..16994)
                     /locus_tag="VXD01_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0602021.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLAMLSIIIS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(17005..17457)
                     /locus_tag="VXD01_001662"
     CDS             complement(17005..17457)
                     /locus_tag="VXD01_001662"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602022.1"
                     /translation="MFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCEGISGIILY
                     LCMYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVI
                     LACSERDDHGLLMFQGDSGKADLFDFGIGSMGVYWCLLNNKFPFDVQT"
     gene            complement(17525..18000)
                     /locus_tag="VXD01_001663"
                     /pseudo
     CDS             complement(17525..18000)
                     /locus_tag="VXD01_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
BASE COUNT         5639 a         3326 c         4149 g         5180 t
ORIGIN      
        1 gttaagcatt gcactttcag aggaaggagt attttttaaa aagaaaatgt aaacgcttgc
       61 tcaaaaatga aaggatttag aagtttatga ataaaggatt atttgaaaaa cgttgtaaat
      121 atagtattcg gaaattttca ttaggtgttg cttctgttat gattggagct gcattctttg
      181 ggacaagtcc ggttcttgca gatagcgtgc agtctggttc cacggcgaac ttaccaactg
      241 atttagctac tgctcttgca acagcaaaag agaatgatgg gcgtgatttt gaagcgccta
      301 aggtgggaga agaccaaggt tctccagaag ttacagatgg acctaagaca gaagaagaac
      361 tattagcact tgaaaaagaa aaaccggctg aagaaaaacc aaaagaggat aaacctgcag
      421 ctgctaaacc tgaaacacct aagacggtaa cccctgaatg gcaaacggta gagaaaaaag
      481 aacaacaggg aacagtcact atccgagaag aaaaaggtgt ccgctacaac caactatcct
      541 caactgctca aaatgataac gcaggcaaac cagccctgtt tgaaaagaag ggcttgaccg
      601 ttgatgccaa tggaaatgca actgttgatt taaccttcaa agaagattct gaaaagggca
      661 aatcacgctt tggtgtcttt ttgaaattta aagataccaa taataatgtt tttgtcggtt
      721 atgacaagga tggctggttc tgggagtata aatctccaac aactagcact tggtatagag
      781 gtagtcgtgt tgctgctcct gaaacaggat caacaaaccg tctctctatc actctcaagt
      841 cagacggtca gctaaatgcc agcaataacg atgtcaatct ctttgacaca gtgactctac
      901 cagctgcggt caatgaccat cttaaaaatg agaagaagat tcttctcaag gcgggctctt
      961 atgacgatga gcgaacagtt gttagcgtta aaacggataa ccaagagggg gtaaaaacag
     1021 aggatacccc tgctgaaaaa gaaacaggtc cggttgttga cgatagcaag gtgacttatg
     1081 acacgattca gtctaaggtc ctcaaagcag tgattgacca agccttccct cgtgtcaagg
     1141 aatacagctt gaatggacat actttgccag gacaggtgca acagttcaac caagtcttta
     1201 tcaataacca ccgaatcacc cctgaagtca cttataagaa aatcaatgag acaacagcag
     1261 agtacttgat gaagcttcgc gatgatgctc acttaatcaa tgcggaaatg acagtacgct
     1321 tgcaagttgt ggacaatcaa ttgcactttg atgtgaccaa gattgtcaac cacaatcaag
     1381 tcactccagg tcaaaagatc gatgacgaaa gaaaactact ttcttctatt agtttcctcg
     1441 gcaatgcttt agtctctgtt tctagtgatc aaactggtgc taagtttgat ggggcaacca
     1501 tgtcaaacaa tacgcatgtc agcggagatg atcatatcga tgtaaccaat ccaatgaaag
     1561 acctagccaa gggttacatg tatggatttg tttctacaga taagcttgct gctggtgttt
     1621 ggagtaactc tcaaaacagc tatggtggtg gttcgaatga ctggactcgt ttgacagctt
     1681 ataaagaaac agtcggaaat gccaactatg taggaatcca cagctctgaa tggcaatggg
     1741 aaaaagctta taagggcatt gttttcccag aatacacgaa ggaacttcca agggctaagg
     1801 ttgttatcac tgaagatgcc aatgcagaca agaaagtcga ttggcaggat ggtgccattg
     1861 cttatcgtag cattatgaac aaccctcaag gttgggaaaa agttaaggat atcacagctt
     1921 accgtatcgc gatgaacttt ggttctcaag cacaaaaccc attccttatg accttggatg
     1981 gtatcaagaa aatcaatctc cacacagatg gtcttgggca aggtgttctc cttaaaggat
     2041 atggtagcga aggccatgac tctggtcact tgaactatgc tgatattggt aagcgtatcg
     2101 gtggtgtcga agacttcaag accctaattg agaaggctaa gaaatatgga gctcatctag
     2161 gtatccacgt taacgcttca gaaacttatc ctgagtctaa atacttcaat gaaaaaattc
     2221 tccgtaagaa tccagatgga agctatagct atggttggaa ctggctagat caaggtatca
     2281 acattgatgc tgcctatgac ctagctcatg gtcgtttggc acgttgggaa gatttgaaga
     2341 aaaaacttgg tgacggtctc gactttatct atgtggacgt ttggggtaat ggtcaatcag
     2401 gtgataacgg tgcctgggct acccacgttc ttgctaaaga aattaacaaa caaggctggc
     2461 gctttgcgat cgagtggggc catggtggtg agtacgactc taccttccat cactgggcag
     2521 ctgacttgac ctacggtggc tacaccaata aaggtatcaa cagtgccatc acccgcttta
     2581 tccgtaacca ccaaaaagat gcttgggttg gggactacag aagttatggt ggtgcagcca
     2641 actatccact gctaggtggc tacagcatga aagactttga aggctggcaa ggaagaagtg
     2701 actacaatgg ctatgtaacc aacttatttg cccatgacgt catgaccaag tatttccaac
     2761 acttcactgt aagcaaatgg gaaaatggta caccggtgac tatgaccgat aacggtagca
     2821 cctataaatg gactccagaa atgcgagtgg aattggtaga tgctgacaat aataaagtag
     2881 ttgtaactcg taagtcaaat gatgtcaata gtccacaata tcgcgaacgt acagtaacgc
     2941 tcaacggacg tgtcatccaa gatggttcag cttacttgac tccttggaac tgggatgcaa
     3001 atggtaagaa actttctact gataaggaaa agatgtacta cttcaatacg caggccggtg
     3061 caacaacttg gacccttcca agcgattggg caaagagcaa ggtttacctt tacaagctaa
     3121 ctgaccaagg taagacagaa gagcaagaac taactgtaaa agatggtaaa attactctag
     3181 atcttctagc aaatcaacca tacgttctct atcgttcgaa acaaaccaat cctgaaatgt
     3241 catggagcga aggcatgcac atctatgacc aaggatttaa cagtggtacc ttgaaacatt
     3301 ggaccatttc aggcgatgct tctaaggcag aaattgtcaa gtctcaaggg gcaaacgata
     3361 tgcttcgtat tcaaggaaac aaagaaaaag ttagtctcac tcagaaatta actggcttga
     3421 aaccaaatac caagtatgcc gtttatgtcg gtgtcgataa ccgtagtaat gccaaggcga
     3481 gcgtcactgt aaatactggt gaaaaagaag tgactactta taccaataag tctctcgccc
     3541 tcaactatgt aaaagcctac gcccacaata cacgtcgtaa caatgctaca gttgacgata
     3601 caagttactt ccaaaacatg tacgccttct ttacaactgg atcggacgta tcaaatgtta
     3661 ctctgacatt gagtcgtgaa gctggtgatg aagcaactta ctttgatgaa attcgtacct
     3721 ttgaaaacaa ttcaagcatg tacggagaca agcatgatac aggtaaaggc accttcaagc
     3781 aagactttga aaatgttgct cagggtatct tcccatttgt agtgggtggt gtcgaaggtg
     3841 tcgaagacaa ccgcactcac ttgtctgaaa aacacgatct atatacacaa cgtggttgga
     3901 atggtaagaa agtcgatgat gttatcgaag gaaattggtc actcaagaca aatggactag
     3961 tgagccgtcg taacttggtt taccaaacca tcccacaaaa cttccgtttt gaagcaggta
     4021 agacctaccg tgtaaccttt gaatacgaag caggttcaga caatacctat gcttttgtag
     4081 tcggtaaggg agaattccag tcaggtcgtc gtggtactca agcaagcaac ttggaaatgc
     4141 atgaattgcc aaatacttgg acagattcta agaaagccaa gaaggcaacc ttcctcgtga
     4201 caggtgcaga aacaggggat acttgggtag gtatctactc aactggaaat gcaagtaata
     4261 ctcgtggtga ttctggtgga aatgccaact tccgtggtta taacgacttc atgatggata
     4321 atcttcaaat cgaagaaatt accctaacag gtaagatgtt gacagaaaat gctctgaaga
     4381 actacttgcc aacggttgcc atgactaact acaccaaaga gtctatggat gctttgaaag
     4441 aggcggtctt taacctcagt caggccgatg atgatatcag tgtggaagaa gcgcgtgcag
     4501 agattgccaa gattgaagcc ttgaagaatg ctttggttca gaagaaaacg gctttggtag
     4561 cagaagactt tgaaagtttg gatgcgccag ctcaaccagg tgaaggccta gagaatgctt
     4621 ttgatggcaa tgtgtctagt ctatggcata catcatgggg cggaggagat gtaggcaagc
     4681 ctgcaaccat ggtcttgaaa gaagcaactg aaatcactgg acttcgttat gttccacgtg
     4741 gatcaggttc aaatggtaac ttgcgtgatg tgaaacttgt tgtgacagat gagtctggca
     4801 aggagcatac ctttactgca actgattggc cagataacaa taagccaaaa gacattgatt
     4861 ttggtaagac aattaaggct aagaaaattg tccttacagg tactaagact tacggagatg
     4921 gtggcgataa ataccaatct gcagcggaac ttatctttac tcgtccacag gtagcagaaa
     4981 cacctcttga cttgtcaggc tatgaagcag ctttggctaa ggctcagaaa ttaacagaca
     5041 aagacaatca agaggaagta gctagcgttc aggcaagcat gaaatatgcg acggataacc
     5101 atctcttgac ggaaagaatg gtggaatact ttgcagatta tctcaaccaa ttaaaagatt
     5161 ctgctacgaa accagatgct ccaactgtag agaaacctga gtttaaactt agctctttag
     5221 cttccgatca aggtaagacg ccagattata agcaagaaat agctagacca gaaacacctg
     5281 aacaaatctt gccagcaaca ggtgagagtc aatctgacac agccctcttc ctagcaggtg
     5341 ttagcctagc cctatctgct ctctttgtag taaaaacgaa gaaagactag tatttagtaa
     5401 aacctcttaa caagattacg gaagcagtct ctatcttttc caatgaggtt tatagtacag
     5461 aaaaagtctg agaagatgtc ttctcagact tttgttaagc acataaatac aatagtgcta
     5521 tgacaaaatc acccagaaaa tctgggtgat aaatgttatg gttgtgctgg ttgaggattc
     5581 tgattttgtt gatcaggggt tgtatttgat tgttgcgtat tattgttagg attggtagtc
     5641 gtactattat ttgtgcttgg agtggttgag ctagactgtg aagttgaact atctgatgat
     5701 gagcttgaac tttcagttga tgggggttgt tgtggagcag gtgagctcca cgtagaacga
     5761 gcaccatttt taaatacgaa ttctccattt ctgtagagcc cctctggtat attccaatcc
     5821 tctggattgc ttccttcaga caggtaggtc atcatagagc ggtaaacttt ggcagcgacc
     5881 gtaaggccat tgcctacaag tggtgtcaga cggttagaat agcctgtcca tacagccatt
     5941 gaatatttac gcgtatagcc agcaaatagt tcatcaggtg ctacaaattg agaggtcttg
     6001 atgtggtttt caatttcctc gtctgtatag ttagaggttc ctgttttacc agcctgaggg
     6061 agccaagcaa gataggcatt tcgtccagtt ccataagtca agactgtttt catcatgtcg
     6121 gtcatcatat aggctgtcgt ttctttcatg gcacgagttc cgacattaga gaactctttt
     6181 tcactcccat cactaaagac gactttatgg atatacattg gtttatagta agttccacca
     6241 tttgcaaagg cagcgtaagc agcagccatc ttttcactac ttgctccata ttttttgtct
     6301 gattcggttg tgttacttga aatggcattt gagtagtgaa tacttgggta gtcgattcct
     6361 agaccattta ggaaagtctt ggcgcggttg agtccgacct tgtttagagt ttccacggct
     6421 gggacgtttc gcgattgttg cagggcgtat tgcaaggtga tgttgccaaa gtagccccta
     6481 tcccagttat aaacaggagt atttgtccca gggtagttat agggctcatc gtgaacgata
     6541 gtagcagttg aatcgtagac accgtactcc aaggcaggag catagtctgt gatcggtttc
     6601 atagttgatc cccagtcgcg gtttgtttct actgcttggt taattccgaa ggaaacatta
     6661 cttgactgat ggcgtgctcc tagctgggca atgactttac cgttagaaac atcaacaatg
     6721 gtagaagcga cttgcaattc atcgtctgga taggcaacgt attcgtctgt attgtaaata
     6781 tcccacagat gtttttgagc ttcttggtct acatttgtgt agacatccat cccagttgtg
     6841 agcaggttat agcctgtttc ttcttcaact tgattgatga cttccttgag gtaattatcc
     6901 atgtaagcag ggtaattact tgctgatttg agactttgta gtccatcagt aattggtgta
     6961 ttgactgctt tctcatactg ttcagcagag atgtagcctt gatttttcat ttcagataag
     7021 accaagtttc ggcggtcttg ggctgcttct ggatgtgaat aggggtcata ttggtttggt
     7081 gcctgaggca ttccagccag caaggctaac tgaggtaaac ttaaattatt gaggtcttta
     7141 ccatagtagt tttgagctgc tgtctgcatt ccatagttcc cattagacat gtagacctta
     7201 tttatatagt aggtcaagat ttcttgcttg gttgcttttt gttctaactg aatcgctaac
     7261 caagcttcct gagccttacg agaaatagtc tggtcggaag tcgaagttga aaagtaagtc
     7321 aacttaatca actgttgagt gagagttgat ccaccttgga gggaattgct ttgcagattg
     7381 cgcaagaaag ctcccaggat acggatggta tcaatccccc tgtggtcgaa gaagcgatgg
     7441 tcttcgatag aaacgattgc cttaaccaaa tctgtgggaa tatcattagc ttgggcattg
     7501 acgcggcgtt cagaacccaa gtcagcaatg agttgatttt tattgtcgta gattttacta
     7561 gaagttgttg caactagttt actctcggat aggctaggag ccttgctaac gtagtagaaa
     7621 aaaactcctc cgcctaagac aatggctgcg ataaccaagc ttaagaagct aatgctcaga
     7681 tacttgatta ggcgcagaat cgttggtttg ttcatcttgt tttaccacct aataaatgtt
     7741 ctttgataac attgagataa ggaatttgag gaaaggcacc agccttgatt tcatatccat
     7801 attctcgaat atattcaagt ggcattgatt tttgtccctt atcttgatga tagaagcgaa
     7861 tcaaatcgaa tgccggcaat aagtaggttt cttgctgaga agaaaagtga agaaggacaa
     7921 agcagattcc ttgttgggca aggacttgtt ccatatgctg aatctgatgt ggatgaaaat
     7981 ttttcatcgg aatcgcacgt ttttgttttg tttccttgac ttcaaagtcg atgtaatatc
     8041 cattataaac gccagaatag tccgtcgttg aagcttgtcg aaaataggct tcaacaatct
     8101 tggcacgact tcgttgtgga tagtccactt gtacgatttg aataggagtt ggtttcttat
     8161 gtatgacagc caagccctga gacaaatagt agtcgttggt agcattgatc atcttttcaa
     8221 aagacattcc tcgatttgcg aaatttttgg gttgagaaag agatttttgt cttttttgtg
     8281 atgaaacttt atgtggatag ttgaccataa ttctccttat tggtacaata acatcacttt
     8341 attatatcat aatttgcaca gaaagggtta aaaatggcta cagctttggt tttaggctat
     8401 tctgcttttg atttgggttt attttctgat aaggatcctc gtcttaaatt gattaaaaaa
     8461 gcgatacgta aagatttaga ggctatggca gcagatgggg tgtcttggct tgtgtttaca
     8521 ggaagtttgg gttttgaata ttgggtttta gaggttgctc aggagatgaa aaccgaatac
     8581 ggtttccagt tggccaccat ttttgctttt gaaacccatg gggaaaattg gaatgaaggc
     8641 aatcagatga aactgagtcg ctttaagcag gtagactttg tcaaatatgc ttatcctcgc
     8701 tatgaacaca aggggcagtt aagagattac cagcagtttt tgctggaaaa cacgactagt
     8761 tcctatcttt tttatgatga agaaaatgaa ataaaactag cttattttta ccaaaagatg
     8821 aaaaatcaag aggactattt tataaagaga ttaacatttg atcaattaaa tgaacttgct
     8881 gaaaattttt ccgaaaattg aagctttgac cttgattttt gtttgccttt ttttatataa
     8941 taatactagc aagcgagaat ggagagagac atggcaagta ttattttttc agcgaaagat
     9001 atttttgaac aagagtttgg acgtgaagtc cgtggctata ataaagtaga agttgacgag
     9061 tttttagacg atgtcatcaa ggactatgaa acctatgctg ccttggtcaa gtcacttcgt
     9121 caggaaattg cggatttgaa ggaagaatta actcgtaaac cgaaaccttc accagttcaa
     9181 gcagaacccc ttgaagcggc aattacaagt tctatgacga attttgatat tttgaaacgc
     9241 ctgaatagat tggaaaaaga agtttttggt aaacaaattt tagataactc agatttttaa
     9301 gtagttattt gagatgtgca atttttggat aatcgcgtga ggagaattgc ttctcatgag
     9361 gaaagtccat gctagcacag gctgtgatgc ctgtagtgtt tgtgctaggc gaaaccataa
     9421 gcctagggac gagaaatcgt tacggcagtt gaaatggcta agtccttgga taggccagag
     9481 taggcttgaa agtgccacag tgacggagtc tttctggaaa cagagagagt ggaacgcggt
     9541 aaacccctca agctagcaac ccaaattttg gtcggggcat ggagtacgcg gaaacgaacg
     9601 tagtattctg actgctatca gctagagctg ttagtggtag acagatgatt atcgaaggaa
     9661 gtggtcctag tcacttctgg aacaaaacat ggcttataga aaattgcata taggttgggg
     9721 ctgagaaatt ttctcaacct cattttttaa agtggacata tagaaaggtc ttgcaagact
     9781 gtaacatgaa aaaagaattt aatttaattg caactgtggc agcagggctt gaggctgtcg
     9841 ttggtcgtga agtgcgagag ttgggctacg attgtcaggt tgaaaatgga cgtgttcgtt
     9901 ttcaaggaga cgtgagagct attatcgaaa ccaacctttg gcttcgggca gcagatcgta
     9961 tcaaaattat cgtaggaacg ttcccagcta agacttttga agagctattt cagggagttt
    10021 tcgctttaga ttgggaaaat tatttaccac ttggagctcg gttcccgatt tcaaaagcta
    10081 aatgtgttaa gtccaaactt cacaatgagc ccagtgttca ggctatttct aagaaagctg
    10141 ttgtcaagaa attgcagaaa cactatgctc gcccagaagg ggttcctctg atggagaatg
    10201 gtccagagtt taagattgag gtctctattc tcaaagatgt ggcaactgtc atgattgata
    10261 cgaccgggtc tagcctcttt aaacgtggtt atcgtaccga aaaaggtggc gctcctatca
    10321 aggaaaatat ggcagcagcc attttacaac tttctaactg gtatccagac aagcctttga
    10381 ttgatccgac ctgtggttcg gggactttct gtattgaggc agttatgatt gctagaaaga
    10441 tggcgccagg tcttcgtcgc tcttttgcat ttgaggaatg gaactggatc agcgatcgct
    10501 tgattcaaga agtgcgcaca gaagcggcta aaaaagtaga ccgtgagctt gagctggata
    10561 tcatgggctg tgatattgat gctcgcatgg tggaaattgc taaggccaat gctcaggcag
    10621 ctggtgttgc aggagacatt acttttaagc agatgcgcgt gcaggattta cgttccgata
    10681 aaatcaatgg agtaatcatt tccaatccgc cttatggtga acgtttgtca gatgatgcag
    10741 gggtgaccaa gctctatgct gagatggggc aagtatttgc accgctgaaa acttggagca
    10801 aatttatcct gactagtgat gaagcttttg aaagcaagta tggtagccaa gcagataaga
    10861 agcgtaagtt atacaacgga accttgaaag tggatctgta tcaatatttt ggtcagcgtg
    10921 tcaaacggca agaggtaaaa tagaaaggga tactcatgag taaaaaaaga cgaaatcgtc
    10981 ataaaaaaga aggtcaagaa ccgcaatttg attttgatga agcaaaagag ctaacagttg
    11041 gtcaagctat tcgtaaaaat gaagaagtgg aagcaggagt cttgcctgag gattccattt
    11101 tggacaagta tgttaagcaa cacagagatg aaattgaggc ggataagttt gcgactcgtc
    11161 aatacaaaaa agaggagtta gttgaaactc agagtctgga tgatttaatt caagagatgc
    11221 gtgaggctgt agaggagtca gaagcttctt cggaggaagt tccatcttct gaagacatct
    11281 tactaccctt gcctctggac gatgaggagc agggcttgga tcctctattg ttagatgatg
    11341 aaaatccaac agaaatgact gaagaagtgg aagaggagca aaacctttct cgtctggatc
    11401 aagaggactc agaaaagaaa agtaaaaaag gctttatttt gaccgttttg gcgcttgtat
    11461 cagtaattat ttgtgtcagt gcttattatg tctaccgtca agtggctcgt tcgaccaagg
    11521 aaattgaaac ttctcaatca actacagcca atcaatcgga tgtggatgat tttaatacac
    11581 tttatgacgc cttttacaca gatagcaata aaacggcttt gaaaaatagc cagtttgata
    11641 aactgagtca actcaaaacc ttgcttgata aactggaagg tagtcgtgaa catacgcttg
    11701 ccaaatctaa atatgatagt ctagcaacgc aaatcaaggc tattcaagat gtcaatgcac
    11761 aatttgaaaa atcagctatt gtggatggtg tgttggatac caatgccaaa gccaaatcgg
    11821 atgctaaatt tacggatatt aaaactggaa atacggagct tgataaagtg ctagataagg
    11881 ctattagcct tggtaagagc cagcaaacaa gtacttctag ctcaagttca agtcaagcaa
    11941 gctcaaatac gacaagtgag ccaaaaccaa gtagttcaaa tgagactaga agtagtcgca
    12001 gtgaagtcaa tatgggtctc tcgagtgaag gggttgctgt tcaaagaagt gccagtcgtg
    12061 ttgcctataa tcagtctgct attgatgata gtaataactc tgcctgggat tttgcggatg
    12121 gtgtcttgga acaaattcta gcgacttcac gttcacgtgg ctatatcact ggagaccaat
    12181 atatccttga acgtgtcaat atcgttaacg gcaatggtta ttacaacctc tataagccag
    12241 atggaaccta tctctttacc cttaactgta agacaggcta ctttgtcgga aatggcgctg
    12301 gtcatgcaga tgacttggac tactaagcag tcgttacaaa attctttctt ttcaaaagta
    12361 aaaatgataa aataaaacaa atgaaacaag aggagtgtca aatgacaaaa gctaactttg
    12421 gtgtcgtagg tatggccgta atgggtcgta accttgccct taatattgaa tcacgtggtt
    12481 acacagttgc tatctacaac cgtagtaaag aaaaaacgga agatgtgatt gcttgccatc
    12541 ctgaaaagaa ttttgtacca agctatgacg ttgaaagttt tgtaaactca atcgaaaaac
    12601 ctcgtcgtat catgctgatg gttcaagctg gacctggtac agatgctact atccaagccc
    12661 ttcttccaca ccttgacaag ggtgatatct tgattgacgg aggaaacact ttctacaaag
    12721 ataccatccg tcgtaatgaa gaattggcaa actcaggtat caactttatc ggtactggag
    12781 tttctggtgg tgaaaaaggt gcccttgaag gtccttctat catgcctggt ggacaaaaag
    12841 aagcctacga attggttgcg gatgttcttg aagaaatctc agctaaagca ccagaagatg
    12901 gcaaaccatg tgtgacttac atcggtcctg atggagctgg tcactatgtg aaaatggttc
    12961 acaatggtat cgagtacggt gatatgcaat tgatcgcaga aagctatgac ttgatgcaac
    13021 acttgctagg cctttctgca gaggatatgg ctgaaatctt tactgagtgg aacaagggtg
    13081 aattggatag ctacttgatt gaaatcacag ctgatatctt gagccgtaaa gacgatgaag
    13141 gccaagatgg accaatcgta gactacatcc ttgatgctgc aggtaacaag ggaactggta
    13201 aatggactag ccaatcatct cttgaccttg gtgtaccatt gtcactgatt actgagtcag
    13261 tgtttgcacg ctacatttca acttacaaag aagaacgtgt acatgctagc aaggtgcttc
    13321 caaaaccagc cgccttcaac tttgaaggag acaaggctga attgattgaa aaaatccgtc
    13381 aagcccttta cttctcaaaa atcatttcat acgcacaagg atttgctcaa ttgcgtgtag
    13441 cctctaaaga aaacaactgg aacttgccat ttgcagatat cgcatctatc tggcgtgatg
    13501 gctgtatcat ccgttctcgt ttcttgcaaa agattacaga tgcttacaac cgtgatgcag
    13561 accttgccaa ccttcttttg gatgaatact tcttggatgt tactgctaag tatcaacaag
    13621 cagtgcgtga tatcgtagct cttgcggttc aagctggtgt gccagtgcca actttctcag
    13681 cagctattac ttactttgat agctaccgtt cagctgacct tccagctaac ttgatccaag
    13741 cacaacgtga ctactttggt gcccacactt accaacgtaa agacaaagaa ggaaccttcc
    13801 actactcttg gtatgacgaa aaataagtag gtcagccatg gggaaacgga ttttattact
    13861 tgagaaagaa cgaaatctag ctcatttttt aagtttggaa ctccagaaag agcagtatcg
    13921 ggttgatctg gtagaggagg ggcaaaaagc cctttccatg gctcttcaga cagactatga
    13981 tttgatttta ttgaacgtta atctgggaga tatgatggct caggattttg cagaaaaatt
    14041 gagtcgaact aaacctgcct cagtcatcat gattttagat cattgggaag acttgcaaga
    14101 agagctggaa gttgttcagc gttttgcagt ttcatacatc tataagccag tctttatcga
    14161 aaatctggta gcgcgtattt cggcgatctt ccgaggtcgg gacttcattg atcaacactg
    14221 cagtctgatg aaagttccaa ggacctaccg caatcttagg atagatgttg aacatcacac
    14281 ggtttatcgt ggtgaagaga tgattgctct gacccgccgt gagtatgacc ttttggcgac
    14341 acttatggga agcaagaaag tattgactcg tgagcaactg ttggaaagtg tttggaagta
    14401 tgaaagtgcg accgagacaa atatcgtaga tgtctatatc cgctatctac ggagcaagct
    14461 tgatgttaaa ggtcaaaaaa gctacattaa aaccgtgcgt ggtattggtt acaccatgca
    14521 agaatagaaa agcagttgca gttgtgtaac tgcttttttg aggagttttt atatattgac
    14581 atgcagtcgg gtctttgcta caatcgtttt aggaggatat atagatgaaa cttttgaaaa
    14641 aaatgatgca agttctacta gcagtctttt tctttggttt gctagctaca aatacggtat
    14701 ttgcgaatac cacaggtggc cgatttgttg ataaggataa tagaaaatat tatgtaaaag
    14761 atgatcataa agcaatctat tggcataaaa tagacggtaa aacttactat tttggtgata
    14821 ttggagagat ggttgtcggt tggcaatact tagaaattcc tggaacaggt tatcgtgatg
    14881 atttatttga taatcgtcca gtcttcgaaa ttggccttca ggagaagtgg tactattttg
    14941 gacaagatgg tgctttgcta gaacaaacag ataaacaagt actagaggca aaaacgtctg
    15001 aaaatacagg aaaagtatac ggtgaacaat atcctctatc tgctgaaaag agaacttatt
    15061 attttgataa taattatgct gtaaagacag gctggattta tgaagacggc aattggtatt
    15121 atttaaataa gctaggaaat tttggtgatg attcttacaa tccactacca attggtgaag
    15181 ttgctaaggg ttggactcaa gattttcatg ttactattga cattgataga agcaaacctg
    15241 ctccatggta ctacctagat ccaacaactg gtattatgca aacaggttgg caatatctag
    15301 gtaataagtg gtactacctc cgttcctcag gagcaatggc cactggctgg tatcaggaag
    15361 gtaccacttg gtattattta gaccagccaa atggcgatat gaaaacaggt tggcaaaacc
    15421 ttgggaacaa atggtactat ctccgttcat caggagctat ggcaactggt tggtaccaag
    15481 atggttcaac ttggtactac ctaaatgcaa gtaatggaga tatgaagaca ggttggttcc
    15541 aggtcaatgg caactggtac tatgcttata gctcaggtgc tttggcagtg aatacgaccg
    15601 tagatggcta ttctgtcaat tataatggcg aatgggttcg gtaatgacag ggcgcttata
    15661 attatattag aacactcgct taatcaaaga agtgactttg ttgtacttga cctgacgatt
    15721 ggggagatta aaagcatgtg aaatctacac atgctttttc gttagttatg agtgttgaac
    15781 ttgactaacc attgacaaaa gataagagca atcaaaataa gatacaaaaa tatcaatgct
    15841 aactgcaccg aaacgcccga tgctatggac agggctaata gggagagcag ggacggggcg
    15901 agaatgtcta ctgtgctcag agcagagccc accgtcccca tcttgtcact ggggatatgg
    15961 gcaaagacag ctgcttgtag gcgagggctg agaatgccga taatcgtaga actgatgaaa
    16021 ctggtcatga aaattacgat ataggcttga caaaggatac tagttattag agccaatagg
    16081 gaaatctcac agaaaaccaa gaggtgcgtg aaacggatat ttttaaatag attactgctg
    16141 gtcatattgc caaggatagc tccacaagaa atgatgatgg agagcatggc gaggagttgc
    16201 ccaatgctca gttgtgctag tgtctgttgg atgaagcgga gggcaatcag ccgaggggac
    16261 acatccaaga tggcaatcat actggtcgtc agaaacagta gtatgacggt atcttttaac
    16321 ctcaggagca cagccagcga ctgtttaaga tgttgaaaat atttcttaaa actcagtgct
    16381 gtatgtgaca tttcaatcct tttttcaacc tcatacaagg tatgtcgaat aacatacagg
    16441 cccaaaaagg caatgacaaa agtcagagtg ttgataaggg aaatagtttg aatactcata
    16501 acattgataa ggaatgcgcc agccagattg gcgacaatgc ggacaaccct catcagagac
    16561 tgcctgaacc ccatggcatc atgcaggtcg tccttaatta cactgatgta gagggcgttc
    16621 atcatgtagg cagacaggta gctcaaggtg tcagagatga ggttgatgat gacaatcata
    16681 atgactgaaa ctaatgaaaa gggcgacaag acgagaaata ctgtcaaaat agcgtagagc
    16741 aggattttga ttttggcaat ccagagtgcg tgtttgactc tattttcttg aaaatctcct
    16801 agaatcccga gaaagagttg cgatagtagg ggaaccatct ctgaaatgga aatcagtaaa
    16861 attgctagcg gagcgaaatt gtactgagcc acataattga taatggcgag gtagaaaata
    16921 ctgtcgccga atgatgaaaa acagctgttt agcagcaact gtctatatat gttgtttgtc
    16981 caaaataatt tcatactttt ctccttatgt ctgcacatcg aatgggaatt tattatttaa
    17041 tagacaccaa tataccccca tgcttcctat tccgaagtca aacaaatctg ctttaccact
    17101 atctccttga aacatcagta aaccgtgatc atctcgttca gaacatgcta aaattacctg
    17161 ttggattttt ttcatcagta atttgttttg attgtagaca gtggtttgta gtaagctagt
    17221 tattccgtgg caatatcctg tcatcatttt tagatgatgg ttaaaaacaa attcttgata
    17281 tttactaata atatctttgt ttccgtcaca atcgtacata caaagatata agattattcc
    17341 ggaaattcct tcgcaccaag aaagttgtaa atttcctaaa ttttcagtat tagaagtaac
    17401 tttttctaat aattttttta attcagtatg gaatgtatgg agatcattat agaacataga
    17461 aggttctaag actttagaat aggcaaataa agcctatgca attccacaat atccatgagc
    17521 aaagctatag tctaaaatgc tttctttggc tatatctctt tgtaggaaat aatgctaaat
    17581 ttcccctata ctattgtgga tgaaaatttt aagagtattg tcattggtaa attgatagta
    17641 ttttattaat gataatagga caccagattt tcccaatgca aagtctattt cctctagagt
    17701 atcataattc tctattaatt tcttagcgga gacgtttgct aattgtagat agtattgatt
    17761 tttactgata gaaaataaat gtaggagtaa ccatagatag cctgcatcac caaatagcag
    17821 tgagtattga tatttatatg tgtgtgtcgt tctaattgtc actgccttct tgatgataga
    17881 gagtatttta gaatccagtt ctggggggta caatttattt agaggaaaca gtagtccagc
    17941 tattccgtgt tggaatgata aattacttac gaaatttcca aattctgttg aagaagtgat
    18001 ccttccttca gaatttacag ttttatctag taaaaatcgt agaacactat tacattctgt
    18061 tttgtaatca tatttatgtt cctctatttt tttaattttg actaaattat ttgtttgact
    18121 taaatttagt agacattgta accaaaatag ttgctcatct gtgagctgac cttgagtatg
    18181 tgatagttct agtaattgaa taggatcctt tagttagatt caatcaatct ataacacaac
    18241 aacataataa tacttttagg ataacttgtc aaatattata gtaaaatgaa ataa
//
LOCUS       DAVLDI010000047        18130 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLDI010000047 DAVLDI010000000
VERSION     DAVLDI010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18130
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.047"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            372..1418
                     /gene="pheS"
                     /locus_tag="VXD01_001664"
     CDS             372..1418
                     /gene="pheS"
                     /locus_tag="VXD01_001664"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV0602023.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1418..1927
                     /locus_tag="VXD01_001665"
     CDS             1418..1927
                     /locus_tag="VXD01_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0602024.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GIGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            2004..4409
                     /locus_tag="VXD01_001666"
     CDS             2004..4409
                     /locus_tag="VXD01_001666"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV0602025.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENTVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIGTDK
                     APYYAARILDNVIIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPREELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQVSLEEKVNA
                     EVR"
     gene            complement(4477..5478)
                     /locus_tag="VXD01_001667"
     CDS             complement(4477..5478)
                     /locus_tag="VXD01_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV0602026.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVRDLDIVSFQNSDHRCIFTEITF"
     gene            5625..6028
                     /locus_tag="VXD01_001668"
                     /pseudo
     CDS             5625..6028
                     /locus_tag="VXD01_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6154..6420
                     /locus_tag="VXD01_001669"
     CDS             6154..6420
                     /locus_tag="VXD01_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0602027.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            6681..8930
                     /gene="metE"
                     /locus_tag="VXD01_001670"
     CDS             6681..8930
                     /gene="metE"
                     /locus_tag="VXD01_001670"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV0602028.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFNEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            8994..9860
                     /gene="metF"
                     /locus_tag="VXD01_001671"
     CDS             8994..9860
                     /gene="metF"
                     /locus_tag="VXD01_001671"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV0602029.1"
                     /translation="MSCQTPSLSFEVFPPNPAVGNDNIILALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIELIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNEHFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10545..12758
                     /gene="pnp"
                     /locus_tag="VXD01_001672"
     CDS             10545..12758
                     /gene="pnp"
                     /locus_tag="VXD01_001672"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV0602030.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEVRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12774..13391
                     /gene="cysE"
                     /locus_tag="VXD01_001673"
     CDS             12774..13391
                     /gene="cysE"
                     /locus_tag="VXD01_001673"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV0602031.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHSFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHAVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13403..14287
                     /locus_tag="VXD01_001674"
     CDS             13403..14287
                     /locus_tag="VXD01_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0602032.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14374..15717
                     /locus_tag="VXD01_001675"
     CDS             14374..15717
                     /locus_tag="VXD01_001675"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV0602033.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15710..16096
                     /locus_tag="VXD01_001676"
     CDS             15710..16096
                     /locus_tag="VXD01_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV0602034.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16100..16984
                     /locus_tag="VXD01_001677"
     CDS             16100..16984
                     /locus_tag="VXD01_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV0602035.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            17121..17720
                     /locus_tag="VXD01_001678"
     CDS             17121..17720
                     /locus_tag="VXD01_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602036.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGYNFSSVSSS
                     SQTAKYEGTGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            17863..18033
                     /locus_tag="VXD01_001679"
                     /pseudo
     CDS             17863..18033
                     /locus_tag="VXD01_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         5456 a         3482 c         4102 g         5090 t
ORIGIN      
        1 catttataga aattaatttt actttcccaa tcgatttgtt ttcatcttat ttcaatccgc
       61 tataaagtta gataagaata agctaacaag cagaagtaag ataggtcttg caagaatggt
      121 aaaaatctga taaactaagt agtaattgaa taggaatctg aaagactagt agcccaaggg
      181 aagtatatca gggaggagag ccgtgactgc aagctctcta tatgaaagct gggtgaattc
      241 acttgcgcat ggatttagaa atgaaggtct gacttgtcag atgaaaacgg atggtaccgc
      301 gtgtcaacgc tccgagtgga gtttttggca tgtggttttc tttttatcta cgagagactg
      361 atggaggaaa tatgtcaact attgaagaac aattaaaagc gcttcgcgaa gaaacgctgg
      421 ctagcttgaa gcagattact gctggaaatg aaaaagagat gcaagatttg cgtgtctctg
      481 tccttggtaa aaagggttcg ctcactgaaa tcctcaaagg gatgaaagat gtttctgctg
      541 agatgcgtcc aatcatcggg aaacacgtca atgaagctcg tgatgtcttg actgctgctt
      601 ttgaagaaac agctaagctc ttggaagaaa agaaagtcgc ggctcaactg gctagcgaga
      661 gtatcgatgt gacgcttcca ggtcgtccag ttgcgactgg tcaccgtcac gttttgacac
      721 aaaccagtga agaaatcgaa gatatcttca tcggtatggg ttatcaagtc gtggatggtt
      781 ttgaagtaga gcaagactac tataactttg aacgtatgaa ccttccaaaa gaccacccag
      841 ctcgtgatat gcaggatact ttctatatca ctgaagaaat cttgctccgt acccacacgt
      901 ctccagttca ggcgcgtgct atggatgccc atgatttttc taaaggtcct ttgaagatga
      961 tctcgccagg gcgtgtcttc cgtcgcgata cggacgatgc gacccacagt caccaattcc
     1021 accaaatcga aggcttggta gttgggaaaa atatctctat ggctgatctt caaggaacgc
     1081 ttcagttgat tgtccaaaaa atgtttggtg aagagcgtca aattcgtttg cgtccatctt
     1141 acttcccatt cacagagcca tctgttgagg tggatgtttc ttgcttcaag tgtggtggag
     1201 aaggctgtaa cgtatgtaag aaaacaggtt ggatcgaaat tatgggagcc ggtatggttc
     1261 acccacgtgt ccttgaaatg agtggtatcg atgcgactgt atactctggt tttgcctttg
     1321 gtcttggaca agagcgtgta gctatgctcc gttatggaat caacgatatc cgtggattct
     1381 accaaggaga tgtccgcttc tcagaacagt ttaaataatg attagaaaag tagaaatggc
     1441 agatgttgag gtgttggcta aaattgccaa acaagccttt cgtgaaacct ttgcgtatga
     1501 taatacggaa gagcagttac aggaatactt tgaagaggct tatagtctga aaactttgtc
     1561 aactgagttg ggaaatcctg actctgaaac ctatttcatt atgcatgagg aggagatagc
     1621 tggttttctc aaagtcaact ggggaagtgc tcaaactgag agagaattag aggacgcttt
     1681 tgaaattcaa cgcctctatg tgctacaaaa attccaagga tttggaatag gtaagcaact
     1741 gtttgaattc gcacttgaac ttgctacaaa aaatagtttt tcttgggctt ggctaggtgt
     1801 ttgggagcat aatacaaaag ctcaagcgtt ttataatcga tatggttttg aaaaatttag
     1861 ccaacatcat tttatggttg gtcaaaaagt agatacggat tggttactga gaaagaaatt
     1921 aaggtaagaa gaggattctt ctattgaaat gataggaaag gaaaagaacc agtgtggcaa
     1981 tggtcattct ggagaactaa attatgcttg tatcttataa atggttaaaa gaattggtgg
     2041 acattgatgt gccatcacag gagttggctg aaaaaatgtc aaccacaggg atcgaggtag
     2101 agagtgtcga atcaccagct gctgatctct caaaaattgt tgtcggtgag gtcttgtctt
     2161 gcgaagatgt gccagagact cacctccatg tttgtcaggt taacgttggc gaagaagaag
     2221 cccgtcagat cgtttgtggt gccccaaatg tgcgtgctgg gatcaaggtc atggtggctc
     2281 ttccaggagc tcgtatcgct gataactaca aaatcaaaaa aggaaaaatc cgtggtttgg
     2341 agtcacttgg aatgatctgt tcacttggtg aattgggaat ttctgactca gttgtgccta
     2401 aggaattcgc agatggcatc caaatcttgc cagaaaatac cgtgccaggt gaggaagtct
     2461 tttcttacct agacttggat gatgaaatca tcgaactttc catcacacca aaccgtgcag
     2521 atgccctttc tatgtgtgga gtggctcacg aagtggcagc catctatgac aaggcggtca
     2581 actttaaaga atttactcta acagaaacta atgaagctgc ggcagatgcc ctttctgtca
     2641 gcattgggac agacaaggcg ccttactatg cagctcgtat cttggacaat gtgattatcg
     2701 caccaagtcc acaatggttg caaaaccttc tcatgaacga aggcatccgt cccatcaata
     2761 acgttgtaga cgtgacaaac tacatcctgc tctactttgg tcaacctatg catgcttttg
     2821 acttggacac atttgaaggg actgacatcc gtgtgcgtga agcgcgtgct ggtgaaaaat
     2881 tggtgacctt ggacggtgaa gaacgtgact tggacgtgaa tgacctagtc atcactgttg
     2941 cagacaagcc agtagccctt gcaggtgtca tgggtggtca agcaacagaa atctctgaaa
     3001 aatctagtcg tgttgtcctt gaagctgctg ttttcaatgg taaatctatc cgtaagacaa
     3061 gtggtcgcct gaaccttcgt tcagaatcgt cttctcgctt tgaaaaaggc atcaatgtgg
     3121 caacagtcaa tgaagccctt gatgcggcag ctagcatgat tgcagaactt gcaggtgcga
     3181 cggtgcgtaa gggtatcgtt tcagcgggtg agcttgatac ctctgatgtg gaagtttctt
     3241 caacccttgc tgatgttaac cgtgtcctcg gaactgagct gtcttatgct gatgtcgaag
     3301 acgtcttccg tcgtcttggt tttggtcttt ctggaaatgc agacagcttt acagtcagcg
     3361 taccacgtcg tcgttgggat atcacaatcg aagctgacct ctttgaagaa atcgctcgta
     3421 tctatggata tgaccgcttg ccaactagtc taccaaaaga cgatggtaca gctggtgaat
     3481 tgactgtgac acaaaaactc cgccgtcaag ttcgtaccat tgctgaagga gcaggtttga
     3541 cagaaatcat cacctatgct ctaacaactc ctgaaaaagc agttgagttt acggctcaac
     3601 caagtaacct tacggaactc atgtggccaa tgactgtgga tcgttcagtc ctccgtcaaa
     3661 atatgatttc aggtatcctt gataccgttg cctacaacgt ggctcgtaag aataaaaact
     3721 tggcccttta cgagattgga aaagtctttg aacaaacagg taatccaaga gaagaacttc
     3781 caaatgaaat taacagtttt gcctttgcct tgacaggctt ggttgctgaa aaagatttcc
     3841 aaacagcagc agttccagtt gatttcttct atgctaaggg aatccttgaa gccctattta
     3901 ctcgcttggg actccaagta acctatacag caacatctga aatcgctagc cttcatccag
     3961 gtcgtacagc agtcatttca ctcggtgacc aagttcttgg tttccttggc caagtgcatc
     4021 cagtcactgc taaggcttat gatattccag aaacgtatgt agctgagctt aacctttcag
     4081 ctatcgaagc tgcgcttcag ccagcgactc catttgtaga aatcaccaaa ttcccggcag
     4141 tcagccgtga cgttgccctt ctcctcaagg cagaagtgac tcatcaagaa gttgtagatg
     4201 ctatccaagc tgccggcgtg aaacgtttga cagatatcaa actctttgac gtcttctcag
     4261 gtgagaaatt gggacttggt atgaagtcaa tggcttatag cttgaccttc caaaatccag
     4321 aagatagctt aacggacgaa gaagtcgcac gctatatgga aaaaatccaa gtatcgctcg
     4381 aagaaaaagt gaatgcagaa gtgcgttaaa cgatagtatg atacaaattc cccctctagt
     4441 ttatgaacac tagaggggtg attttatata aaataattaa aatgtgattt ctgtaaaaat
     4501 acatctatga tcagagtttt gaaaacttac aatgtctaaa tctctaacat agtagtggtt
     4561 tttaggcaat aagatatgat ctatcgttgc attaaaaagt tttggacttt ggctattcca
     4621 agttcctctt tcaaaaggtg gaagtgcatt caatgcgtcc ctatgagagc ttatttttgc
     4681 aagtgctcca tgacgcatag ttgcattaaa atcacctgca ataatagcct ttggatattt
     4741 tgaagccaat tgattatgaa tgatgtttaa gtcttgcttc cagatttcca ttaaacctgg
     4801 cagaggagga gcagtatgca aggcaatgat atctggtata ttttgttttc tcgaatgtaa
     4861 tacaattgtc ccgaaccgtg ttgtatgaaa agttttagct tctgtataga aaccataact
     4921 tttcttgaca atcacagtca caggagctat tccactattg gtaggtggag aagtgaaaat
     4981 atcatagttg gccatagaaa gtccaacttg atgaaacaat agtttgattc tctggttttc
     5041 ttgctcacct ctgatattgg tagctagttc agggaatata gccatatcgg catcaaaatg
     5101 gctaaaaatt cgctcaatat gttgtgcttc tatttgatta gcgacgttcc aagttactaa
     5161 ttttaaggtt ttagtcttat ttgatgcaga agaaagggtt ttatctgttc cgaataatag
     5221 taatatgagc gatagtaaga gcaaaatgcc agagtaaaac cgtatttgtt tatttttctt
     5281 gtaaaaagat agggaaaaaa atacgaaact taaaatagaa gccatagttg cagtagctaa
     5341 ggggaaggca taaatctgtg ccaagatagg tctggtagat agccaaatat taagattaga
     5401 agatggaaaa aaagaataag ctatgatagg gataacaaag agaatgaccg aaagggcaga
     5461 gagaaatgtt ttaatcattg tgtgagtacc tcaatttgca atggttgctc ggagctaatg
     5521 tgactttact tgattgatat tctttttctt gtcttcctca tagattaagt acaacccaag
     5581 taaaaaagtt caatttaaga ttgaaatgat taaaaggcac agaaatgcaa gacaattata
     5641 ctacaaaagg caaacatttg acaatcgata gccgtcgctt aatcgaacga tggaaaaaag
     5701 aaggaaaatc aaatagagaa attgcctctc tacttggaaa agctcctcaa actatccaca
     5761 ctgaaatcaa gcgtgggaca gtccgacaat gtcttggaaa agggcgcttc aaagagattt
     5821 attctgccga ctacgctcaa cagtcttaag aaactaaagg aaaagattct ccactataca
     5881 taaccaaaaa ttttcgcctg aaatgatggt gatggctaaa ggggttaacg tgggaatttc
     5941 aaccatttac tattggattc atcgtggaaa attggggtta agcaagcagg atctgcttta
     6001 tcctagaaaa ggaaaatcgc ttaagaaata ggctagcacc aactttaaac ccgctggtca
     6061 atctatcgaa tcataattcg ctcatttttt taaaaataca tagacgtaaa aaaaagaggg
     6121 ttaagtgatg aagaatagtg ctattgggag taattggaag gatgtccatc tgagctcttt
     6181 agcaaggagg aaatccttga aagtgatatg cgagtggcta tcatgagcga gttgattgag
     6241 gctaggtatg aacaaggaat cagtcagaaa aagctggaag aagtcagtgg aataagccag
     6301 cctgtcatag ctaggatgga gacaggagag agcagtcttc agttggatac ggtcttaaaa
     6361 gttctaacca gtctaggaaa gacactagca gtcgttccac ttgaacaggg gaaaagttga
     6421 ctagaatcag ttatagtctt ttctaataac aggtcatagt cacttataag aattactaat
     6481 aacatgtttt agtattctaa ttggaatata gctgtaaagt aagaattaca aaggatttga
     6541 gatgtttgct tcaagtcttt ttcttttgtc cgaaacagat atatagtttc aaactatatc
     6601 aaaccctaat tttttacaat tatacagacg ctttcttttc tgttaagata gtttcaacaa
     6661 caaattttgg aggacacatc atgtcaacta caatcatcgg tttccctcgt ttgggcgaat
     6721 tccgtgaatt aaaatttaca actgaaaaat actttagaaa agaaatctca gaagaagaac
     6781 ttttagcagc agcaaaagac ttgcgtgcta aacactggaa cattgtcaaa gaaaaaggca
     6841 tcactgaaat tccatcaaat gacttttctc actatgataa cttcctagat gcggctttcc
     6901 ttttcaacgt ggtgcctgca tccgttcaaa acttggactt gtctgacctt gagcgctact
     6961 tcgctttggg acgtggttac cagggagaaa aaggggacgt tcgcgccctt ccaatgaaga
     7021 aatggttcaa cactaactac cactacatcg ttcctaaatt tgaaaaagac actcaagtaa
     7081 aattggctgg tcacaagatt ttcaatgagt tccaagaagc aaaagaactt ggattgaaca
     7141 ctcgtcctgt tcttgtaggt cccttcactt tccttcaatt gtcagacttt gaagaaggcg
     7201 tgaaagcaga cgacttcgta gatagcttag tagttgctta ccaagaagtt tttgctaaat
     7261 tggctgaact tggtgcgact cgcatccaat tggatgaagc ggctcttgta aaagacttga
     7321 cagctgaaga aaaagctctc ttcttgaacc tttacaacaa actcttggct gacaaaaaag
     7381 gtcttgaagt cttgcttcaa acttatttcg gtgatgttcg tgacgtatac gctgaccttg
     7441 taaacttacc agtagatgct atcggtcttg actttgttga aggtaagaaa actcttgaac
     7501 tcgttaaagg tggcttccca gctgacaaga ctctctatgc aggtattgtc aatggtaaaa
     7561 acatctggcg taacaactac gaaaagagct tggctgttct tgagcaaatc ccagctgaaa
     7621 acatcgtttt gacaagctct tgctcacttc ttcatgtgcc atttacaact gctaatgaag
     7681 aatttgaacc agcactcttg aaccactttg cctttgcagt tgaaaaattg gatgaaatcc
     7741 gtgacttgga tgctatccgc aatggtcaag gttcagaagc tcttgcagcc aacaaagaac
     7801 tctttgcgac tgagcgtgtt ggtgaaaatg ctgaacttcg tgcgcgtatc gctggcttga
     7861 cagacgcaga ctacactcgt ttgccagcct ttgcagaacg tgaagctatc caagaagaag
     7921 cttttaaact tccagctctt ccaacaacaa cgattggttc attccctcaa acaaaagaag
     7981 ttcgtgccaa acgtttggct taccgtaaag gtgaattgtc tcaaaaagag tacgacgctt
     8041 tccttgctga aacgattgac gaatggatca agtggcaaga agatattgac tttgatgtcc
     8101 ttgttcacgg tgaatttgag cgtaatgaca tggttgagta cttcggtcaa aacttgtcag
     8161 gatacctctt ctctaaaaat ggatgggtac aatcatacgg tatgcgtggg gtaaaaccac
     8221 caatcatctg gggtgatgtc actcgtctta accctatcac tgttaaatgg tctagctatg
     8281 cacaaagtcg tacaaacaaa cctgttaaag gtatgttgac tggacctgtt accatcctca
     8341 actggtcatt cccacgtgaa gacatctcta tcaaggattc tactcttcaa atcgcccttg
     8401 ctatcaagga tgaagtgctt gaccttgaag ctgctggtgt gaaaatcatc caaattgatg
     8461 aggctgctct tcgtgaaaaa ttgccactcc gtcgtagtga ctggtacgaa gattaccttg
     8521 actgggcaat tcctgccttc cgcttggtac actcaacagt agcgtcagac acacaaatcc
     8581 acactcacat gtgttactca gaatttacag atatcatccc agctatcgat aacatggatg
     8641 cagacgttat ttcctttgaa gccagccgtt caaaccttga aatcttggac gaactcaaag
     8701 cgaaaaactt ccaaacagaa gtgggacctg gggtttacga tatccactca cctcgtgtac
     8761 caaatgaagg cgaaatcgac aacacaatcg aagccatcct tgctaaagtg ccaagcaaga
     8821 aagtttggat caaccctgac tgtggtttga aaacacgtgg tatcccagaa acaaaagaaa
     8881 gcttgatccg ccttgttgaa gcagctaaag ctgcgcgtga gaaattgtaa gattggattt
     8941 ctctccatac agtggttgtt caaaaagaaa tcaactagaa aaggttatta catatgtcat
     9001 gccaaacacc gtcactctca tttgaagtgt tccctccaaa cccagccgtg ggtaatgata
     9061 acattatttt agccttgcag gatatgcagg agttggctcc ccattttatc agtgtaactg
     9121 ccagcaataa taaatttaat atcaaggaaa cgacggttcg tttggctgac tttatccaaa
     9181 atgacttggc gattccgacc attgcccact tgccagctat ttatctaact aaggacaagg
     9241 ttgctgaaac tattgctgac ttggacaaag ttggggtgca gaaaatcttg gctcttcgtg
     9301 gggatattat tccagacgtg gaaccacaaa aggatttccg ctatgcaacc gacttgattg
     9361 agcttatcaa ggaacaagcc cctcactttg atattattgg agcttgctat ccagaagggc
     9421 atccagattc gccaaatcag atttcagata ttcaaaatct taagaagaaa gtggatgcag
     9481 gctgttcgag cctcgtaact cagctcttct ttgacaatga gcacttctat gattttcagg
     9541 acaagtgcat cttggctggg attgatgttc ccattcatgc aggaattatg ccaattctga
     9601 atcgaaatca ggctctccga ctcttgaaga cttgtgagaa tatccatctt ccacgcaaat
     9661 ttaaagccat cttagacaag tatgagcatg accctgagtc gctcagagca gcaggacttg
     9721 cctatgcagt ggaccaaatc gtagacttgg taactcagga tgttgccggt gtgcatctct
     9781 atacgatgaa taatgctgat acagcaaaat acatccatca agcaacccat gccttgttta
     9841 atcaccagtc tctaggataa taaaagcaaa ccattcttct caggtgaggg gaatggttcc
     9901 tttttaatgg taaagacctc actttttaag aaaaatatga taaaataaat tctgtacgta
     9961 cttgatacaa agatgaaggt attaaataat acaatgcatt taaactgtaa gatttaacga
    10021 cacgagtgag tcaaatcgat gttatttgac gagagagtta gtaaagcatt tagctaatcg
    10081 cccgatagcg attagcgtga aagctttaga tactttagta ttaaaccttt ctaatgatgt
    10141 atcttgaaaa ctgaacttgc ctacaactct gtggaaaaag ataaatctcc ctaggagcag
    10201 tcgctccgtc gttcgatttc ctatcttcct ttgagttgct tgacggcttg gtatcttgat
    10261 gacttgaatt ttggtctcat ttcttaggaa aaaagataag cttcctagca ctcgtcgagt
    10321 gcgaagtcac cttcctattt ttctacagaa atgttcggca agccgaaccg tccaaaatat
    10381 cttgtgtaat tgaacacggc cgaaaagctg tgtaaaaaag ataaactgtc ttgtcttcat
    10441 cgaagacttc gtcagtttcc tatttttact ttgcttttga cgtccttggt atcttgatct
    10501 ttgtaggcaa ggcgtataat ttcatcaatc caaaggggat taaaatggca aaacaagtgt
    10561 ttcaaacgac ttttgcgggt cgtgagttaa ttgtagagac tggtcaggtt gctaagcaag
    10621 caaatggatc tgttgtcgta cgttacggtg agtcaactgt cttgactgct gccgttatgt
    10681 ctaagaaaat ggcaactggg gatttcttcc cactccaagt caactacgaa gaaaaaatgt
    10741 atgcggctgg gaagtttcct ggtggcttta tgaaacgtga aggacgtcct tcaacagatg
    10801 cgaccttgac agcgcgtttg attgaccgtc cgattcgtcc tatgtttgcg gaaggtttcc
    10861 gtaatgaagt ccaagtcatc aatacagtgc tttcttatga tgaaaatgca tctgcaccaa
    10921 tggctgctat gtttggttca tctttggcac tgtctatttc agatattcca tttgacggac
    10981 caattgctgg ggtacaagtg ggatatgtag atggccaaat catcatcaac ccaagtcaag
    11041 aacaagcaga gcaatctctt cttgaattga cagtagctgg aaccaagcac gctatcaaca
    11101 tggtagagtc tggtgccaaa gaattgtcag aagaaatcat gttggaagcg cttcttaaag
    11161 ggcacgaagc tgtcaaagaa ttgattgcct tccaagaaga aatcgttgct gctgtcggta
    11221 aagaaaaagc agaagtggaa ttgcttcacg tggatgctga attgcaagct gaaatcattg
    11281 cagcctacaa cagtgacctc caaaaggcag ttcaagtaga agagaaattg gcccgtgaag
    11341 ctgcaactca agcagtgaaa gaccaagtga ctgccgttta cgaagaaaaa tatgcggacc
    11401 acgaagaatt tgaccgtatt atgcgtgatg tggctgaaat cttggaacaa atggaacacg
    11461 cagaagtgcg acgtttaatt acagaagaca aggtgcgtcc tgatggtcgt aaggtcgatg
    11521 aagtccgtcc tttggatgcg gttgttgact tccttcctcg tgtacatggt tcaggtctct
    11581 ttactcgtgg gcaaactcaa gctctttcag tcttgacctt ggctccgatg ggagaaactc
    11641 aaatcattga tggtttggat ccagagtaca agaaacgctt tatgcaccac tataacttcc
    11701 ctcaatattc tgtaggggaa acaggtcgtt acggtgcgcc aggtcgtcgt gaaatcggtc
    11761 acggtgctct tggtgagcgt gctcttgctc aagtcttgcc aagcttggaa gaattcccat
    11821 acgctatccg tctagtagca gaagttttgg aatcaaacgg ttcttcatct caagcttcta
    11881 tctgtgcggg aactcttgcc cttatggctg gtggtgtgcc aatcaaggcg ccagtagctg
    11941 gtattgctat gggacttatc tcagatggaa ataactacac agtattgaca gatatccaag
    12001 gtttggaaga tcactttgga gatatggact tcaaggttgc aggtactcgt gatgggatta
    12061 cagcccttca aatggatatc aagattcaag ggattactgc agaaatcttg acggaggctc
    12121 ttgctcaagc caagaaagcg cgttttgaaa tccttgatgt cattgaagca accattccag
    12181 aagttcgtcc agaattggct ccaactgctc cgaaaattga tacgatcaag attgatgtgg
    12241 acaagattaa gattgtcatc ggtaagggtg gagaaaccat cgacaagatt attgctgaaa
    12301 caggtgttaa gattgatata gacgaagaag gaaatgtgtc tatctactct agtgaccaag
    12361 atgctattaa ccgtgccaaa gaaattattg ctggtttggt tcgtgaagcc aaagtggatg
    12421 aagtttaccg tgctaaagtc gttcgtatcg agaaatttgg tgcctttgtt aacctctttg
    12481 ataagacaga tgcccttgtt catatctctg agatggcttg gactcgtacc aatcgtgtag
    12541 aggatttggt agaaatcggg gatgaagttg atgttaaggt tatcaagatt gatgaaaaag
    12601 gccgtatcga tgcttctatg aaggctcttc tacctcgtcc gccaaaacct gagcatgatg
    12661 aaaaaggtga aaagtctgag cgccctcacc gcccacgtca tcacaaggat cacaaaccta
    12721 agaaagaatt tacagaaaca ccaaaagatt cagaataaga aaaggagaaa tgtatggggt
    12781 ggtggcgcga aaccattgat atcgtaaaag aaaatgatcc agcggcccgc accactttgg
    12841 aggttttgct gacttatcca ggtgtcaagg ccttggcggc ccaccgtctc tcgcattttc
    12901 tctggaagca cagcttcaaa ctcttagctc gtatgcacag tcagttttgg cgcttttgga
    12961 ctcagattga gattcatcca ggagcccaga ttgattcagg tgtctttatt gaccatggtt
    13021 ctggtctggt gattggagag acagcgattg ttgaaaaagg cgttcttctc tatcacggag
    13081 tgactcttgg gggaacaggg aaagactgtg gcaaacgcca tccgactgta cgaaagggag
    13141 ccctcatatc agcccatgcc caagttatcg gacctgtgga aattggtgaa aatgccaagg
    13201 tcggtgctgc agcagttgtc gtagcagatg tacctagtga tgtgacggtt gtcggtattc
    13261 cggccaagat tgtccgtctt catggtaaga aagatgagcc tgttattcac gcagtcgaag
    13321 aaaaacgaga gtattatgtc aataaactcg agcaggctaa agatgccagt cacagatcgt
    13381 ctggtttgta gaggatacct atatgattca agcaagaaac aagttaagcc aagaggagct
    13441 atctgaggcg aaaaaagtaa ttaactgttg ccaaaactat gacggtacct atcgcgatcc
    13501 ctatctctct aacatgctta attttgaccc aaacatgccc gcctttttcc tttattatga
    13561 aaaaggcaaa cttgttggtt tattaactgt ctatgcagat gaccaagatg tagaagtgac
    13621 gatactggtt catccaggtc atcgccgtca ggggattgcg cgtgcattgt ttactagttt
    13681 tgagagagaa acagcttctt tccctattcg gtcagtcact tttcagacag aacgtatttt
    13741 tttagagaat catcctgact ttgccagtaa ctggggacta atcgaggatg aagagacaga
    13801 aacttggtta ggtaaggata gaagacctta tccgttagca aatgtttccc atcttgaaat
    13861 tttgttagca gatagttcgt atcaggatca aattagtcaa ttaaaatttc aggcattttc
    13921 agaggaacat gaatcgagag aagttgtgga tagatatgtc gctgaagctc tgaaagatcc
    13981 agaaagccga ctatatattt tattaaaagc tggtcaggtt attgggactt gcacggttga
    14041 tttatcgagc gatacgaatt acttctacgg tttagcaata tcagaacctg aacgtgggaa
    14101 aggctatgga agctacttag caaaatccct tgtcaaccaa ctaattgagc aaaatgataa
    14161 ggaatttcag attgcagtgg aagatagcaa tgtaggtgcc aaacgtttgt atgaaaaaat
    14221 tggctttgtc aaacagacac aggtggttta tctgaatgag aaaggagcaa gggattccga
    14281 agtgtagaga cattcggact gaaatttact tgagctctta gtttagtgat gaaactaaca
    14341 gttcttggat tttagctttc ctgattatga tttatgatta aaatctatga caccatgtct
    14401 cgtgatttgc gagaatttgt cccgattgag gacggcaaga tcaagatgta tgtttgtggg
    14461 ccaacggtgt acaactatat ccacgtggga aacgcccgtt cgacggtagc ttttgatacg
    14521 attcgtcgct attttgagta ccgtgggtat aaggttgcct atatttccaa ttttacagat
    14581 gtggatgata agattatcaa ccgtgccagg gaagaaggca tcacgcctca ggaggttgcg
    14641 gataagtaca tcgctgcctt tcgtgaggat gtgacggcct tgggcgtgaa acctgcgact
    14701 cgccatccgc gtgtagtgga gtttatggca gacatcatcc gttttgtgga agacttgatc
    14761 gagaaaggct ttgcctatga gagtcaaggg gatgtctatt tccgtgtaga aaaatcccac
    14821 aactatgcta aattggctaa taaaaccttg gaagatttgg agctaggtgc ttcaggtcgt
    14881 accgatgaag aaacggctcg taaggaaaat cctgtagact ttgctctatg gaaatcttcc
    14941 aaaccaggtg agatttcttg ggatagtcct tggggacctg gacgtccggg ttggcatatt
    15001 gagtgttcag tcatgtcgac agagatttta ggtgatacca ttgatatcca cggtggtgga
    15061 gctgacctag agtttccaca ccacaccaat gaaattgccc aatctgaagc taaaacaggc
    15121 aaggcttttg ctaactactg gatgcacaat ggctttgtca atatcgacaa tgtcaaaatg
    15181 tctaagtcct tgggtaactt cattacggta cacgatgccc ttaaaactct tgatgggcaa
    15241 gtacttcgtt tcttctttgc gacccagcac taccgtaagc ctatcaactt cacggaaaag
    15301 gcagttcgcg atgccgagac caatctcaag tatctgaaga atacttacga acaaccattt
    15361 acaggaaacg tggatgccca agagttacaa aactttaaag ataagtttgt agcagctatg
    15421 gatgaagatt ttaatgctgc caacggtatc acagttgtct ttgaaatggc caaatggatc
    15481 aactcaggga actatgatgc aagtgtcaag caagctcttg cagatatgtt agaaattttt
    15541 ggaattgtct ttgttgagga agttttggat gcagagattg aagacttgat tcaaaaacgc
    15601 caagaggcgc gtgccaatcg tgactttgcg acagcagacc aaatccgtga ccaattggtt
    15661 actcaaggaa ttaagctcct tgataccaag gatggagtga ggtggacacg tgattgatgt
    15721 caatctcatt aacgggattg cgctagcctt tgagggggat gcggtgtatt ctatgtatat
    15781 tcgccgtcac ctcatcctca aaggtatgac caaacccaat aaactccatc aagaagcaac
    15841 caagtatgtg tcagccaagg ctcaggctcg cctgattgct ctcatgttgg aggagcaggt
    15901 cctaacggaa aaagaagaag aaatctacaa acgtggccgc aataccaata gccacacaaa
    15961 ggctaaaaat gcagatgtcg tgacttatcg tatgtccacg ggatttgaag cggttatggg
    16021 ctatctccat atgactgaga atctggaacg tcttgagagt ttggtttcat ggtgcatcca
    16081 aaaagtggag ggctagaaca tgagggaaaa agaactacaa gactggtttc ctgaggctcg
    16141 gatttcagac caaccagtag agaaagaggg ctatctcacg ctccctttag cttctcagca
    16201 gtggattttg ctggaggaag ctgggctcag cgagcgtgaa aagcagttgg ttgccctttt
    16261 gacccagcag gagcaggctc gttcgctaaa cccttggtat tcctatctgg ttgaaggcaa
    16321 gggacaggca ccgcaagttt ttaaaaagat tcagttggtt tattgccatc tttcttattt
    16381 tcagcaggaa aatctgactt cttggctaga tatgatgcgg actctttttc cgaattgtca
    16441 gacagtgcta caggtcggag ctcaggatta tgttttcgtg cttcaacaag acaaatacac
    16501 ttctgtaaga gatattttaa gtgatacgat tgaagcggtt gagtatgatt ttggacttcg
    16561 tctttctatc atgttgggtc aggtttggtc tcagacagga catcaagccc tatcagactt
    16621 aatcaaagct gagcgggatt tgttcaagac atggtggcgt cagggtcacc aaggtgttca
    16681 tactttttct cagctctatc tttggagtat gggagaaaga ctcgtggact tgaagccaat
    16741 taaagaatgt ctacaccaga tgattttgga tcaagatcag attcaggaaa tcattctctc
    16801 tctttgggaa aatagtgctg ttctcactaa aacagcccag caactctatc tgcaccgcaa
    16861 ttctctccaa tacaagattg ataaatggga agagttgaca gggcttcagt tgaaagagtt
    16921 gaccgacctg accttgtgtt atcaattgat tttaggttct ttgtcaacta tagttggttt
    16981 gtaaagaagt taatatttgg agaagaggat tgccatcttc tccattttta tgtgcagagt
    17041 tatagtggct tgatgctggg aaagtacact gtgactgcta aaacattcct agaagctgct
    17101 ttgatttccc taatctattt atgcaaattt tatgttattt tactataaca gttgttgcta
    17161 agccaaataa tagtggggaa gttcatttag acgtaagcat tgaagataat cagggaggta
    17221 gtgggtataa tttcagttct gtttcaagta gctcacaaac agctaaatat gaaggaactg
    17281 gttataataa caattcatca ttatatataa cgattgataa aacgtctgat gcaacagctc
    17341 ttttgaaatt aaagttgaat aatgttgata atcaacctgc tactgaagtt cctagttcag
    17401 gaattactgt aaaattaaat gctaaagata atgctggaaa ctggacaagt gcttcgaata
    17461 aaaaagaagt aacagtaaaa attgtttctg ctaaaccgac atatccagac aaaatcttag
    17521 tgaaaaatcc tgataatata aaagatacag aaaaaaatgc cattattgaa aaattgaaag
    17581 aggcaaataa aaatcatcca gcaggagctc caacctttgc taaaggtgaa ggagagcatg
    17641 caaatgatat tgtagcaact tattcagatg gtacaactta ttatgtaccg ttaaatgatg
    17701 tgacaaaata tgcgaggtag tggctgtacc actcacttat tcacctcccc gtgatttgta
    17761 gtagtgatag gctttctcac tattattata aaacaaaata aagatcacaa cactttttca
    17821 ttctgtgttg tgccttgagt gaaacgaaag gaatgaatta taaatatgaa aagtatagtc
    17881 actagcatag atgagcgctt gcgtactcgc ctacgagtga ttatctggaa gcaatggaag
    17941 aagaaatcga gacgattatg gggattgctt aagttagggg ttcctaaatg gatagcagat
    18001 aaggtatctg gctggggcga ccactatcaa ttatagtaaa atgaaataag aataggacga
    18061 atcgatcagg gaagtcaaat cgatttctaa caatatttta gaagtagagg tatattattc
    18121 tagtttcaat
//
LOCUS       DAVLDI010000048        17462 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLDI010000048 DAVLDI010000000
VERSION     DAVLDI010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17462
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.048"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(26..961)
                     /locus_tag="VXD01_001680"
     CDS             complement(26..961)
                     /locus_tag="VXD01_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV0602037.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAGSLFKATAPITRNELIIEIWRTFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GFAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(958..1818)
                     /locus_tag="VXD01_001681"
     CDS             complement(958..1818)
                     /locus_tag="VXD01_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0602038.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            1926..4088
                     /locus_tag="VXD01_001682"
     CDS             1926..4088
                     /locus_tag="VXD01_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV0602039.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIYKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLEHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQFLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKNLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4180..5439
                     /locus_tag="VXD01_001683"
     CDS             4180..5439
                     /locus_tag="VXD01_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0602040.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5453..6319
                     /locus_tag="VXD01_001684"
     CDS             5453..6319
                     /locus_tag="VXD01_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0602041.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6333..7166
                     /locus_tag="VXD01_001685"
     CDS             6333..7166
                     /locus_tag="VXD01_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0602042.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7477..8919
                     /gene="gtfA"
                     /locus_tag="VXD01_001686"
     CDS             7477..8919
                     /gene="gtfA"
                     /locus_tag="VXD01_001686"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV0602043.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9057..10250
                     /locus_tag="VXD01_001687"
     CDS             9057..10250
                     /locus_tag="VXD01_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV0602044.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            10936..12915
                     /locus_tag="VXD01_001688"
     CDS             10936..12915
                     /locus_tag="VXD01_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0602045.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            12982..14478
                     /locus_tag="VXD01_001689"
     CDS             12982..14478
                     /locus_tag="VXD01_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0602046.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14478..15404
                     /locus_tag="VXD01_001690"
     CDS             14478..15404
                     /locus_tag="VXD01_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0602047.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15413..16480
                     /locus_tag="VXD01_001691"
     CDS             15413..16480
                     /locus_tag="VXD01_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602048.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKEWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16491..17417
                     /locus_tag="VXD01_001692"
     CDS             16491..17417
                     /locus_tag="VXD01_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602049.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
BASE COUNT         5136 a         3113 c         3668 g         5545 t
ORIGIN      
        1 tcgtttatat tataattgtg ttattttact tccaactatt gagagaaatt tcgccactat
       61 ttagccagat ttcttttccg ttatcacatt gaactaaaag ttttccattt tctgagatgt
      121 ctttagcaaa tcccttgtag tctttttgct ctagtgtgaa agtgacttct tttcctagaa
      181 tgaatgactg ttttttgtat aggtataata gctcttctgc tggtgtttcg aagaaagtac
      241 gccagatttc tatgatcaat tcattccttg ttataggagc tgtagcttta aataagctgc
      301 cagctttttc ttttaattcc tgagggaagt ctttaatagt gaaattgata cctactccaa
      361 taatgatatc tgtgactaag ccagtttcta cagaggtcat tgcttcagta aggattcctc
      421 caattttatg attgtttaga tagatatcat tgacccattt tatgtcgaca tctattaaag
      481 ttaggttctt aatggctttg tagacagctc cagctacaag tagtgtgtag gatggtaatt
      541 tgtcataggg gagatttggt ttaagatgga gtgtcatata aataccacct tgtggtgagt
      601 agaaggaacg ttgaaaacgg cctcggcctg ctgtttgata ggaagctaga tagagggtat
      661 ttgcttcatg gcctaaatca attgcttctt ttgcatctag ttgtgttgat tttgtttcgg
      721 gtttaaagct gactttaatt ggaagatttt cttctagaat ctctggaaga ataaggtcac
      781 cattcatcag tttataccct ctatttttga tactatcaat ttcaatgcct tcttgttcta
      841 gtcgcttgat ggctttccaa attgatgttc ggcttaggga tagtttttct gcgatttttt
      901 ctccgctgat atagtcggtt tctttagata ggatttggta gacagcttgg taggatttca
      961 taatgttgcc tttcttacta gttggtattg agagtattct tttcttgtat gacttggagt
     1021 ctgattaaag tattgtttat aagctttcga aaaatggagt ggatctgaaa aacctaccga
     1081 gtatgcaatt accttgatgg actcttgggt attttcgaga agttgtctag ctcggtgcat
     1141 tcgaacgtag agtaggtatt ctttgggtga taaggtatta aattctttga atacgcttga
     1201 taagtagctt ctgtgaacgg atagttcttt tgctaaatct tgaattgtaa gtgattgagg
     1261 atagtggcta tcaattaatc gtttgcattc aagatagagt tggtgggttg atgaaatatt
     1321 cttttttttc tgattgggag caatagttcc cagatgaaac atcagttcat gaagttgtcc
     1381 catgatatgg agttgagcta attcacttga ttttgtaatc tgagcgaagc ggacaatgtc
     1441 tgagatgagt tttgcagtag tctgggtatg acaagtttca gattggatga gataggattg
     1501 atcagaaatt tgagaaagag caaaataatc aggggatttc cctccagtga ttcctaacca
     1561 gtagtaggcc caaggttctt tactatctgc ttgataaaag gttagttcct ctggttttaa
     1621 tagaaagaaa tctccttctt ttaaatcaac aattttaccc ttgtaatgaa attttccttg
     1681 tcctttagta atgtaatgta ggacgtatgt atcacgaatg gctggaccaa aagagtaatt
     1741 aggtgtgcat tcctcatatc cataaaagct tagggcaagg tcgattgttc cagtctggta
     1801 ttctgaaaaa actaacatgt gctacctcct acctaacatt ttaccatatt cttgagacat
     1861 ttttctattt tagaaagcga tttcaggtga taaaatataa tcaataaagt gatgaggtga
     1921 agtaaatggg agttaggata gagaataatc tattttatgt tgagagtaaa aatctaagtt
     1981 tgattattga aaatcgaaat ggctacttac ttttgaaaca tttaggaaag actattaaga
     2041 actataaagg ttccaatagt gtttatgaac gagaccatgc cttttcagga aatccaacag
     2101 ctactaatcg aacctttagt ttagatactc aacgtcaaat ttttggacaa catggcttag
     2161 gagattttag gaaaccaacc atacaggttc agcataatgt aactgaagta acagactttc
     2221 gatttgtaga agcaaagatt ttaaaaggtc agaatggtcc acagggctta ccttctccac
     2281 atagcatgga cgatacagag actcttgtct taatgttaga agattctaag gctcaactta
     2341 gtctgacttt gtattatact acttttaata atgatgcgac tattgctagc tacagtaaat
     2401 tagataataa tagtaatcag gaagttgtca tctataaaga tttttctttt atggctgatt
     2461 ttccagctgc agattacgaa atagtaactc tgcagggtgc ttatgctcgt gaaaagactg
     2521 ttagacgtca acaggtagaa caaggaatct tttcgattag ttcaaaccga ggtgcttctg
     2581 gtcatgctca aacaccagct cttctactat gcgaacaagg agtcacagag gatgctggga
     2641 atgtgtttgc tattcaacta atgtatagtg gcaactttga agcttttgtt caaaaaaatc
     2701 aattgaatga agttcgggtg gctattggca ttaatccaga aaacttttct tggaagttag
     2761 cccctgagga atactttgaa acaccggtag ctttagtgac tcattcagat cagggattaa
     2821 ctggtattag tcatgaaagt cagaattttg tactggagca cattatgcta agtgaatttt
     2881 ctaaaaaaga acgtccaatt ctaatcaata actgggaagc tacttacttt gactttcaga
     2941 gagaaaaact gttagagtta gcagatgaag ctaagaaagt tggcattgaa ctttttgtat
     3001 tagatgatgg ttggtttggc aatcgttttg atgataatcg tgctttaggt gattgggttg
     3061 ttaatgagga aaaactgggt ggaagtctag aaagtctgat ttcagctatc catgaaagag
     3121 gtttgcagtt tggactttgg ttagaacccg aaatgatttc tgtagatagt gatttgtatc
     3181 gtcaacatcc tgactgggct attcaggttc ctggctatga gcatacttat tctcggaatc
     3241 aattagtact taatcttgcc aatcctcagg tagtagaata cttgaaaagt gtcttagatc
     3301 aattcctatc ttatcatgat attgattaca ttaaatggga tatgaaccgc aatatcacta
     3361 agctagggaa tggattaact tatctagaga cacagatgca atctcatcag tacatgctgg
     3421 ggctttacga actcgtttct tatctgacag agaagcacag ccatattctc tttgagtcct
     3481 gctctggtgg tggtggacga aatgatcttg gtatgatgcg ctatttccca caagtctggg
     3541 ctagtgataa tactgatgcc attgcacgtt taccaattca atacggttca tcctatctct
     3601 atccaaccat ttctatgggg gctcatgtgt cagcagtacc gaatcatcag atgggacgaa
     3661 tgacaccatt agaaacacgt ggccttgtag caatgatggg aaatttgggc tatgaacttg
     3721 atttgacaaa tttatcagat gaagagaaag ctacgattgc taatcaggtg aacttgtata
     3781 aagaattacg accagtagtt cagttaggac agcagtatag actaattaat cctgatactg
     3841 tatccaatga agcagctgta caatttaatt acggaaatca aacgattgta acctacgttc
     3901 gcgttttatc tgttgtagag accatggaaa caactttaaa attaaaaaat ttggatgaag
     3961 agggactata taaattacag gaaaatggcg aagtttactc aggtgcagaa ctaatgtatg
     4021 cgggcctaac tgttatctta tcccaaggag attttttgag tagacagtat atttttagaa
     4081 aactatgata tgtactgacc tcaaaagtta gatttattct atctaacttt tgaggtgcag
     4141 tttgataagg gtgtataaat ttataaagga ggctttctaa tggaatggta taaaaaaatc
     4201 ggacttcttg caactacagg tttagctttg tttgggctcg gtgcttgctc caactatggt
     4261 aaatctgcgg atgacacagt gaccatcgag tatttcaacc agaaaaaaga aatgaccaaa
     4321 accttggaag aaatcactcg tgattttgag aaggaaaacc ctaagataaa ggtcaaagtc
     4381 gtcaatgtac caaatgctgg tgaagtattg aagacacgcg ttctcgcagg agatgtgcct
     4441 gatgtggtca atatttaccc acagtccatc gaactgcaag aatgggcaaa agcaggtgtc
     4501 tttgaagatt tgagtaacaa agactacctg aaacgcgtga aaaatggcta cgctgaaaaa
     4561 tatgctgtaa acgaaaaagt ttacaacgtt ccttttacag ctaatgctta tggaatttac
     4621 tacaacaaag ataaattcga agaactgggc ttgaaagttc ctgaaacctg ggatgaattt
     4681 gaacagttag tcaaagatat cgttgctaaa ggacaaacac catttggaat tgcaggtgca
     4741 gatgcttgga cactcaatgg ttacaatcaa ttagcctttg cgacagcaac aggtggagga
     4801 aaagaagcaa atcaatacct tcgttattct caaccaaatg ccattaaatt gtcggatccg
     4861 attatgaaag atgatatcaa ggtcatggac atccttcgca tcaatggctc taagcaaaag
     4921 aactgggaag gtgctggcta taccgatgtt atcggagcct tcgcacgtgg ggatgtcctc
     4981 atgacaccaa atgggtcttg ggcgatcaca gcgattaatg aacaaaaacc gaactttaag
     5041 attgggacct tcatgattcc aggaaaagaa aaaggacaaa gcttaaccgt tggtgcggga
     5101 gacttggcat ggtctatctc agccaccacc aaacatccaa aagaagccaa tgcctttgtg
     5161 gaatatatga cccgtccaga agtcatgcaa aaatactacg atgtggacgg atctccaaca
     5221 gcgatcgaag gggtcaaaca agcaggagaa gattcaccgc ttgctggtat gaccgaatat
     5281 gcctttacgg atcgtcactt ggtctggttg caacaatact ggaccagtga agcagacttc
     5341 cataccttga ccatgaacta tgtcttgacc ggtgataaac aaggcatggt caatgatttg
     5401 aatgccttct ttaacccgat gaaagcggat gtggattagg agtagagaga ctatgaaaaa
     5461 agtattacaa aaatattggg catgggcttt tgtggtcatc cccctcttgt tacaagcaat
     5521 tttcttctat gtgccgatgt ttcaaggagc cttttacagt tttaccaact ggacaggatt
     5581 gacttacaac tacaaatttg tcggcttaaa caactttaag ctcctcttca tggatccaaa
     5641 attcatgaat gcgattggct ttaccgcaat cattacgatt gccatggtgg ttggtgagat
     5701 tgcactcggg atcttcattg cgcgtgtctt gaactctaaa atcaaaggcc aaaccttctt
     5761 ccgtgcttgg ttcttcttcc cagctgtttt atctggtttg acagtggctt tgatcttcaa
     5821 gcaagtcttc aactacggtc ttccagcgat tgggaatgcc cttcatattg aatttctcca
     5881 aaccagtctt ttagggacta agtggggagc aatctttgcg gctgtctttg tccttctttg
     5941 gcaaggggtg gctatgccca tcatcatctt cctagctggt ttgcaatcta ttccaactga
     6001 gattacagag gcagcaagga ttgatggtgc gactagcaag caagttttct ggaacattga
     6061 attgccttac ttgctaccaa gtgtctctat agtctttatc ctagccctaa aaggtgggct
     6121 gactgccttt gaccaagtct ttgccatgac cggtggtggt ccaaacaatg ccacaacctc
     6181 acttgggctc ttggtttata actatgcctt taaaaacaac caattcggtt atgccaatgc
     6241 cattgccgta atcttgttct tcttaattgt agtgatttcg atcatccaat tgagagtatc
     6301 taagaaattt gaaatttaag aggagaagca tgatgaaaca agatgaaaga aaagccctga
     6361 ttggcaaata cattctattg attctaggat cggttctgat tttagtgccg ctccttgcta
     6421 ccctctttag ttccttcaaa cccactaagg atattgtaga taatttcttt ggctttccaa
     6481 ccaacttcac atgggacaac tttagccgtc tcttagctga tgggattgga ggctattatt
     6541 ggaactctgt cgtcatcact gtcttgtctt tacttgcagt aatgatcttt atccctatgg
     6601 cagcctactc catcgctcgc aatatgagta aaagaaaagc ctttaccatc atgtataccc
     6661 tcttaatcct cggaatcttc gtacctttcc aagtcatcat gattccgatt acggttatga
     6721 tgagtaaact cggtttggct aatacctttg gtttgatctt gctctacttg acctatgcga
     6781 ttccacagac cctctttctc tatgttggct atatcaaaat ctcgattcca gaaagtctgg
     6841 atgaagcagc agagatcgat ggggctaatc aatttacaac ctatttccgc atcatcttcc
     6901 caatgatgaa accgatgcat gcgacaacca tgattatcaa tgccctttgg ttctggaatg
     6961 acttcatgtt gccactcctt gtcttgaacc gggattccaa aatgtggact ctgcctttgt
     7021 tccaatacaa ctacgcaggc caatatttca acgactacgg accaagcttt gcctcttacg
     7081 tggtcggcat tatcagtatc accattgtct atctcttctt ccaacgccat atcatttcag
     7141 gaatgagcaa cggggcagtg aagtaatact caatgaaaat caaagagcaa actaggaagc
     7201 tagccgcagg ctgtacttga gtacggtaag gtgaagctga cgtggtttga agagattttc
     7261 gaatagtata agaagagctc atggaatcta tagtctttga cacagaggaa gagttcagct
     7321 tgttgataat tctatgtaga aaacaagaaa gtagtacttt gtttatcaca gtctatatta
     7381 gtacgagttt gatgataaat agagatttaa aatgaatttt atttatgaag ccagatcata
     7441 tgagacttgg cttcaattag aaaaaggaga gtaatgatgc caattcaaaa taaaaccatg
     7501 ttgattacct attctgatag ccttggaaat aatcttaaag acttatatga taatttggaa
     7561 gagcattttg gagatgctat tggaggagtt caccttttac catttttccc atcaacaggt
     7621 gatcgtggat ttgcgccagt tgactacgac gaagtggact cagcttttgg tgattgggag
     7681 gatgttaagc gtttaggtga gagatattat cttatgtttg attttatgat taatcatatt
     7741 tctcgtcaat ccaagtatta taaggactat caagaaaaac atgaagccag tgaatttaaa
     7801 gatctctttt taaactggga taagttttgg ccagaaaacc gtccgacaca gtctgatgta
     7861 gatttaattt acaagcgtaa ggatcgtgca ccaaagcaag agattgtgtt tgaagatggt
     7921 tcagtggaac atttgtggaa tacctttggt gaggagcaga ttgatcttga tgtgaccaaa
     7981 gaagtaacta tggaatttat ccgtaagacc attcagcact tggcaagtaa tgggtgtgat
     8041 ttgattcgtc tagatgcctt tgcttatgca gtgaagaaat tggatactaa tgatttcttt
     8101 gtggaaccag atatttggga tttattggac aaagttcgag atatcgctgc tgagtatggg
     8161 acagagcttt tacctgagat tcatgaacac tattcgattc agtttaaaat agcagaccat
     8221 gattactatg tttatgattt tgctcttcca atggtgacac tttatactct ttacagttcc
     8281 agaacagagc gtttggctaa gtggttaaag atgagcccga tgaagcaatt tacgacgcta
     8341 gatacccatg atgggattgg agtagtagat gtcaaggata tcctgaccga tgaggagatt
     8401 gactatgctt caaatgaact ctataaggtt ggagccaatg tcaaacgtaa gtactctagt
     8461 gccgagtata acaacttaga tatctaccaa atcaattcaa cctactattc agcgcttgga
     8521 gatgatgatg tcaagtattt tctcgctcgt ctaattcaag cttttgcccc aggtattcct
     8581 caggtttact atgtgggtct attagcaggc aagaatgact tgaaattatt agaagaaact
     8641 aaagaaggtc gaaatattaa tcgtcattac tatagcaacg aggaaatagc aaaagaagtg
     8701 caacgacctg ttgtgaaggc ccttctcaat ctattttctt tccgtaaccg ttcagaagcc
     8761 tttgatctag aagggactac tgagatagag acaccaacag ctcacagcat tgtaatcaaa
     8821 cgtcaaaata aagataagtc cgtaacagca gtagcagaaa ttgatttgca aaatcagact
     8881 tatcgggtaa ttgagaatgg agttgaagta acattttgaa gccttgatat ggtggataaa
     8941 atagggtttt tattttggaa aacgtttcct ttgttttcaa attgctaaaa aagtggtaca
     9001 atataggata gcttactatt atctgaatca gctgatttgg agagaaagga ttcattttga
     9061 aatcaatagg ctttattgaa aagctgaagg ggttgtctag taaagagctg attttattgg
     9121 gaattatcct aagtatcttt ttaccctttt atctttttgt agttgtactc tgtttatata
     9181 ttatcagttt gatttttaca ggagacatga aaagtattct tcagaaaatg ggggagcatc
     9241 cgatgctgct tctttttctt agctatagta ctgttatatc cattcttgca caaaattgga
     9301 tgggtcttgt ggcttcagta ggaatgtttc tatttactat tttctttttg cactatcagt
     9361 cgattttatc ccataaattc tttcgattga ttttgcagtt cgtcttgttt ggtagtgtct
     9421 tgtcagctgc ttttgccagt ttagaacatt tccaaattgt gaagaaattt aactatgctt
     9481 ttctttcacc caatatgcag gtgtggcatc agaaccgggc agaagtgacc ttctttaatc
     9541 ctaattatta tggaattatt tgttgtttct gtattatgat tgctttctat ctgtttacaa
     9601 cgaccaagtt gaattggttg aaagtattct gtgtgattgc aggctttgtt aatctctttg
     9661 gtttgaactt tactcaaaat cgaactgcct ttcctgctat tatcgctgga gcaattatct
     9721 atctctttac gactattaaa aactggaagg ccttttggct tagtattggg gtcttcgcga
     9781 ttggtttgag tttcctcttt tctagtgatt tgggagttcg aatgggtact ttagactctt
     9841 ctatggaaga acgcatttct atctgggatg ctgggatggc cttgtttaag caaaatcctt
     9901 tttggggtga agggccattg acctatatgc actcttatcc tcggatacat gctccttatc
     9961 atgaacatgc ccacagtctt tatattgata cgattctgag ttacggaatt gtgggtacca
    10021 ttttattagt tctgtcttct gttgctcctg ttcgcttgat gatggatatg agtcaggagt
    10081 cggggaaacg tccgattatc ggcctttatc tatctttcct tacagtggtt gctgtgcacg
    10141 gaatttttga cttggctctc ttctggattc agtcaggctt tattttcttg ctagttatgt
    10201 gcagtattcc attggagcat cgaatgttgg tatcggacat gacggattaa gttttataag
    10261 tttgaaatct tctaccttgg gtaggagatt ttttatacga tgggcatgtc gtggatctga
    10321 ggtgtaagtc ctctgtaggg atccactacc ggtgaataca atagcgctcc ccaagcctga
    10381 ctatcgtgag gtagcggatt aaaatggtct ggggatagat cgttttaagt ctgacgcagg
    10441 aaataagaat tgtcagagaa agcaatagtg aaatcgtagg ctatgaatag aaacgtgata
    10501 gcgaggagca tatagtggac aaggtagcga gaaattttaa agtataaaag atagtcttaa
    10561 tctatatgtg taaatcacga aagtaattga attcggaata aggttggtgt gaaaagacat
    10621 agtaaactga atcttgaata ctagaatgat acttctacaa tattgttata atttaatttg
    10681 aattccaaaa tcacattgtt ccgtccgtat ttcattttac tgtatgtctt cctaagctcc
    10741 aaaatttctg tgtcaaattt cctattttca ctgtagtctt tgacacttcg aacgacaatt
    10801 tgaatcatat attcaaaaaa aaatgaaaaa tttgtgccaa caagcctaaa tattctgaaa
    10861 atttgtttga tttttaatgg ataatgtgat ataatggttg tcaatctata attcacataa
    10921 acagaggagt agaaaatgaa aaaaaatcgt gtatttgcta cagcaggtct tgttttatta
    10981 gcagcaggtg tacttgcagc atgcagttct tcaaaatcat ctgattcatc agcccctaaa
    11041 gcttatggct atgtttatac agcagaccca gaaaccttgg actacctgat ttcaagtaaa
    11101 aatagtacaa cagtagtgac ttcaaatggg attgatggtt tattcactaa cgataattac
    11161 ggtaatcttg ctcctgcagt tgcagaggat tgggaagtct ctaaggatgg tttgacctac
    11221 acttataaga ttcgtaaagg ggttaaatgg tttacctctg atggagaaga atatgcagag
    11281 gtgacggcta aagatttcgt gaacggttta aaacacgcag cagataaaaa atcagaagct
    11341 atgtatttag ctgaaaattc ggttaaaggc ttggcagatt atctatcagg aacttcaaca
    11401 gatttttcaa cagttggtgt caaggcggtt gatgattata cgttacaata cactttgaac
    11461 cagcctgaac cgttctggaa ctctaagttg acctattcta ttttctggcc tctgaatgaa
    11521 gaattcgaaa catcaaaagg aagcgatttt gctaaaccaa cagatccgac atccttgctt
    11581 tataatggtc cattcttgtt gaaagggttg actgcaaaat cttctgtaga gtttgtaaaa
    11641 aatgagcaat attgggataa agaaaatgtc cacctagata ctatcaatct agcttactat
    11701 gatggatcag atcaggagtc gctagagcgt aacttcacta gtggagctta tagttatgcc
    11761 cgtctttacc ctaccagctc caactattct aaggttgcag aagaatacaa ggacaatatc
    11821 tattacacac aatcaggctc tgggattgct ggtctgggtg tgaatattga tcgccaaagt
    11881 tacaactata cctctaaaac tacagattca gagaaagtag ctactaagaa ggcattgctt
    11941 aacaaagatt tccgtcaagc cttgaatttt gctcttgatc gctcagctta ctcagctcaa
    12001 atcaatggta aagatggagc agctttagca gttcgtaatt tatttgtaaa accagacttt
    12061 gtttcagctg gtgagaagac ctttggtgat ttagtcgctg ctcaacttcc tgcttatggt
    12121 gatgagtgga aaggtgtgaa tttagctgat gggcaggatg gtttattcaa tgctgacaag
    12181 gccaaggcag agtttgcgaa agctaagaaa gctttagaag cagacggcgt tcagtttcct
    12241 attcatctgg acgttccagt agaccaagca tcaaaaaact acatatctcg tattcagtct
    12301 tttaaacaat ctgtagaaac agttcttggt gttgaaaatg tcgttgttga tattcaacaa
    12361 atgacaagtg atgaattcct taatattact tactatgctg ccaatgcttc atctgaggat
    12421 tgggatgtat caggaggagt ttcatggggt ccagactatc aagacccatc tacttacctg
    12481 gatattttaa aaacaactag cagtgaaact acaaaaacat atttaggatt tgataatcca
    12541 aatagccctt cagtagttca agttggtttg aaagaatacg ataaattagt tgatgaagct
    12601 gccagagaga caagcgactt gaatgtccgt tatgaaaaat atgcagcggc tcaagcatgg
    12661 ttgacagata gttcactctt tattcctgct atggcttctt ctggtgcagc accagtgctt
    12721 tcacgaattg ttccatttac tggagcttct gcgcaaacag gctctaaggg gtcagatgtt
    12781 tacttcaaat atttgaaatt acaagataaa gtggtgacta aggaagagta tgaaaaagct
    12841 cgtgaaaaat ggttgaaaga aaaagctgaa tcaaatgaga aagctcaaaa agaattggca
    12901 agtcatgtga agtaaataat ttctaataga actttctctc catgaggaga aggttctttt
    12961 gggattttta aaggaaataa tatgaaaaaa tatattttta tgcgtgtttt gcggtcattg
    13021 gtttcgattt tcttagtaac gactttgacc tacacgatta tctatacctt ggttcctcga
    13081 aaattgattt tcaagcagga tcctaactat aataaaattg cgacaacggc tgataaacgt
    13141 gataactatg aaaatactgt gtttgagcgt atgggctaca ttgagtatta cgatactaaa
    13201 gagttgcaag aaaaggcaag tagcatggat tcttctgtaa cagtagaagc aaatgcgact
    13261 aataaagcta tttatgaaaa gtacatcaat caattaggtc atggttggac tttgggagaa
    13321 tttactgaaa gtggtcaatt ctatgctact cgtgaaattc caatttttga acgtgttttt
    13381 cacttctatg ctaacttgat tgacattgac catacaaata aaatccaaga ccctgaaaat
    13441 ccagacttga aacgctacct tcgttttgaa aatgatccag ctatcggatg gtcattggtc
    13501 ggttcaggaa ctaaacataa atatctcttg tactttaaca gtcagttccc atttgttcat
    13561 caaaactttg tgaacttgaa tttaggtgac tcttacccaa cctatgctaa tacaccagtt
    13621 cttcaggtta ttactcaagg tcaaggacaa accaaaactg cccaagttca gttcccaaca
    13681 ggtaagaaaa cgtcttctgt aaatatttac tcaagaacct acaagtcacc tagtcaggct
    13741 gactctcgtg aagtagctag ctatgggaaa gatgatcctt atacagcgac tgaaagtaat
    13801 taccaatatc catctatgat tgtcagctct gctattactg gtttgattgg tttggttctt
    13861 gcctatgctc ttgccgtgcc acttggttca gccatggctc gtttcaagaa cacttggatt
    13921 gatagcctct caacagggac tttgaccttc ttgcttgctc ttccaacgat tgccttggtt
    13981 tacatcgttc gattgattgg atcatctatt gcccttccag attcattccc tatcttggga
    14041 gctggagatt ggcgttctta cgttttacca gcagtcatcc ttggtttgtt gggtgctcct
    14101 gttacagcca tttggattcg tcgttacatg attgacttgc aatctcaaga ctttgttcgt
    14161 ttcgctcgtg caaaaggttt gtctgaaaaa gaaatttcaa acaaacacat ctttaaaaat
    14221 gccatggttc cgctggtttc aggaattcct ggtgccatta ttggggttat cggtggtgca
    14281 acccttactg aaacagtctt cgccttccca ggtatgggta aaatgttgat tgactctgta
    14341 aaagcatcta ataactctat ggtcgttggt cttgtcttca tctttacatg tatttctatc
    14401 ttctcacgtc ttttgggaga tatttggatg actattattg acccacgtat taaattgact
    14461 gagaaaggag gcaaataatg tctacaatcg ataaagaaaa atttcagttt gtaaaacgtg
    14521 acgattttgc ctctgaaact attgatgcgc cagcatattc ttactggaaa tcagtgttta
    14581 aacaatttat gaagaaaaaa tcaactgtag tcatgttggg aatcttggta gccatcattt
    14641 tgataagttt catctaccca atgttttcta agtttgattt caatgatgtc agcaaggtaa
    14701 acgactttag tgttcgttat atcaagccaa atgcggagca ttggttcggt actgacagta
    14761 acggtaaatc gctctttgac ggtgtctggt tcggagctcg taactccatc ctcatttctg
    14821 tgattgcgac agtgattaac ttggttatcg gtgtttttgt cggtggtatt tggggtattt
    14881 caaaatcagt tgaccgtgtc atgatggaag tttacaacgt catctcaaac atcccacctc
    14941 ttttgattgt tattgtcttg acttactcaa tcggagctgg attctggaat ctgatttttg
    15001 ccatgagcgt aacaacatgg attggtattg ccttcatgat ccgtgtgcaa atcttgcgct
    15061 atcgtgactt ggaatacaac ttggcgtcac gtactttggg aacaccaacc ttgaagattg
    15121 ttgccaaaaa tatcatgcct caattggtat ctgttattgt gacaaccatg actcaaatgc
    15181 ttccaagctt tatctcatac gaagccttct tgtctttctt cggtcttgga ttaccgatta
    15241 cagtgccaag tttgggtcgt ttgatttcgg attattcaca aaacgtaaca accaatgctt
    15301 acttgttctg gattccattg acaacccttg tcttggtatc cttgtccctt ttcgtagttg
    15361 gtcaaaactt agcggatgct agtgatccac gtacacatag ataggagtag aaatgacaaa
    15421 agaaaaaaat gtaattttga ctgctcgcga tattgtcgtg gaatttgacg ttcgtgacaa
    15481 agtattgaca gccattcgcg gcgtttccct tgaactagtt gaaggagaag tattagcctt
    15541 ggtaggtgag tcaggatcag gtaaatctgt tttgacaaag accttcacag gtatgctcga
    15601 agaaaatggt cgtattgccc aaggtagtat tgactaccgt ggtcaggact tgacagcttt
    15661 atcttctcac aaggagtggg aacaaattcg tggtgctaag attgcgacta tcttccagga
    15721 cccaatgact agtttggacc ccattaaaac aattggtagt cagattacag aagttattgt
    15781 aaaacaccaa ggaaaaacag ctaaagaagc gaaagaattg gccattgact acatgaataa
    15841 ggttggcatt ccagacgcag atagacgttt taatgaatac ccattccaat attctggagg
    15901 aatgcgtcaa cgtatcgtta ttgcgattgc ccttgcctgc cgacctgatg tcttgatctg
    15961 tgatgagcca acaactgcct tggatgtaac tattcaagct cagattattg atttgctaaa
    16021 atctttacaa aacgagtatc atttcacaac aatctttatt acccacgacc ttggtgtggt
    16081 ggcaagtatt gcggataagg tagcggttat gtatgcagga gaaatcgttg agtatggaac
    16141 ggttgaggaa gtcttctatg accctcgcca tccatataca tggagtctct tgtctagctt
    16201 gcctcagctt gctgatgata aaggggatct ttactcaatc ccaggaacac ctccgtcact
    16261 ttatactgac ctgaaagggg atgcttttgc cttgcgttct gactacgcaa tgcagattga
    16321 cttcgaacaa aaagctcctc aattctcagt atcagagaca cattgggcta aaacttggct
    16381 tcttcatgag gatgctccaa aagtagaaaa accagctgtg attgcaaatc tccatgataa
    16441 gatccgtgaa aaaatgggat ttgcccatct ggctgactag gaggaaggaa atgtctgaaa
    16501 aattagtaga aatcaaagat ttagaaattt ccttcggtga aggaagtaag aagtttgtcg
    16561 cggttaaaaa tgctaacttc tttatcaaca agggagaaac tttctcgctt gtaggtgagt
    16621 ccggtagtgg gaaaacaact attggtcgtg ctatcatcgg tctaaatgat acaagtaatg
    16681 gagatatcat ttttgatggt caaaagatta atggtaagaa atcgcgtgaa caagctgcgg
    16741 aattgattcg tcgaatccag atgattttcc aagaccctgc cgcaagtttg aatgaacgtg
    16801 cgactgttga ttatattatt tctgaaggtc tttacaatca ccgtttattt aaggatgaag
    16861 aagaacgtaa agagaaagtt caaaatatta tccgtgaagt aggtcttctt gctgagcact
    16921 tgactcgtta ccctcatgaa ttctcaggcg gtcaacgtca acgtatcggt attgcccgtg
    16981 ccttggtcat gcaaccagac tttgttattg cagatgagcc aatttcagcc ttggacgttt
    17041 ctgtacgtgc ccaagtcttg aacttgctca aaaaattcca aaaagagctc ggcctgacct
    17101 atctcttcat cgcccatgac ttgtcggttg ttcgctttat ttcagatcgt atcgcagtta
    17161 tttacaaggg tgttattgta gaggttgcag aaacagaaga attgtttaac aatccaattc
    17221 acccatatac tcaagccttg ctttcagcgg taccaatccc agatccaatc ttggaacgta
    17281 agaaggtctt gaaggtttac gacccaagtc aacacgacta tgagactgat aagccgtcta
    17341 tggtagaaat ccgtccaggt cactatgttt gggcgaacca aaccgaattg gcacgttatc
    17401 aaaaaggact aaactagtaa tggttttata atttccatgt caatttttat ggaaattagg
    17461 ct
//
LOCUS       DAVLDI010000049        17070 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLDI010000049 DAVLDI010000000
VERSION     DAVLDI010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17070
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.049"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            134..433
                     /locus_tag="VXD01_001693"
     CDS             134..433
                     /locus_tag="VXD01_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV0602050.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWNGHSDKGEAPAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            504..2525
                     /locus_tag="VXD01_001694"
     CDS             504..2525
                     /locus_tag="VXD01_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV0602051.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFIYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDIENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNILYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            2527..3168
                     /locus_tag="VXD01_001695"
     CDS             2527..3168
                     /locus_tag="VXD01_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602052.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            3272..4624
                     /locus_tag="VXD01_001696"
     CDS             3272..4624
                     /locus_tag="VXD01_001696"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV0602053.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVIPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELAIQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            4626..5684
                     /locus_tag="VXD01_001697"
     CDS             4626..5684
                     /locus_tag="VXD01_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV0602054.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            5694..6860
                     /gene="divIB"
                     /locus_tag="VXD01_001698"
     CDS             5694..6860
                     /gene="divIB"
                     /locus_tag="VXD01_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV0602055.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFLSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKATIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESN"
     gene            7126..7827
                     /gene="pyrF"
                     /locus_tag="VXD01_001699"
     CDS             7126..7827
                     /gene="pyrF"
                     /locus_tag="VXD01_001699"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV0602056.1"
                     /translation="MREHRPIIALDFPSFEVVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            7861..8493
                     /locus_tag="VXD01_001700"
     CDS             7861..8493
                     /locus_tag="VXD01_001700"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV0602057.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVDAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQKNWQEG"
     gene            8673..9076
                     /locus_tag="VXD01_001701"
                     /pseudo
     CDS             8673..9076
                     /locus_tag="VXD01_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9172..9936
                     /locus_tag="VXD01_001702"
     CDS             9172..9936
                     /locus_tag="VXD01_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602058.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            9936..10688
                     /locus_tag="VXD01_001703"
     CDS             9936..10688
                     /locus_tag="VXD01_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602059.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            10698..11396
                     /locus_tag="VXD01_001704"
     CDS             10698..11396
                     /locus_tag="VXD01_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602060.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDFLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            11393..12040
                     /locus_tag="VXD01_001705"
     CDS             11393..12040
                     /locus_tag="VXD01_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602061.1"
                     /translation="MNEIITLKNIQLELKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(12127..12993)
                     /locus_tag="VXD01_001706"
     CDS             complement(12127..12993)
                     /locus_tag="VXD01_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0602062.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHLTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(13005..13768)
                     /locus_tag="VXD01_001707"
                     /pseudo
     CDS             complement(13005..13768)
                     /locus_tag="VXD01_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(13769..13970)
                     /locus_tag="VXD01_001708"
                     /pseudo
     CDS             complement(13769..13970)
                     /locus_tag="VXD01_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598330.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter permease"
     gene            complement(14067..14447)
                     /locus_tag="VXD01_001709"
     CDS             complement(14067..14447)
                     /locus_tag="VXD01_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV0602063.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            complement(14407..15075)
                     /locus_tag="VXD01_001710"
     CDS             complement(14407..15075)
                     /locus_tag="VXD01_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV0602064.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRIPV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVVLPSFSANVIFLIKKTSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFGNPST
                     LSRK"
     gene            15302..15448
                     /locus_tag="VXD01_001711"
     CDS             15302..15448
                     /locus_tag="VXD01_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV0602065.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            15576..17066
                     /gene="lysS"
                     /locus_tag="VXD01_001712"
     CDS             15576..17066
                     /gene="lysS"
                     /locus_tag="VXD01_001712"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV0602066.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLKEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
BASE COUNT         5145 a         3030 c         3668 g         5227 t
ORIGIN      
        1 attttttcct tgacaacaaa taataaaaat gttattctta tcacataaga aagcggtttc
       61 aacaaaagag agaggaggat ttattttgtt gcattgttgc tcagggtgtg ctttttttga
      121 aagaaaaaat aaaatgaaaa cgaaaaaaca tagattactt gctctagctc ttatttcaag
      181 ttttacatta ttgggagctg catcagctgc tgtacaatat ccagatggag gagtatggac
      241 atatggagaa ggttcaggag gtggttgggc tttttcaaat tactatcatg gtaaaaaata
      301 tcattattca tccatcgtga gcagatggaa tggtcattct gataaaggag aagctcctgc
      361 tggaaaaacc tcctatgcat ggatttggac taaatgggga gaacaagtag cattttactg
      421 tgattatgac taatcgttca ttgatttaaa tcgttcccct tgtaagaaat tacaggggga
      481 attttgttta caaggagtct actatgaaga aactattcat attattatca actttttttc
      541 tcagcttctt ccttgcttgg attattgtct tacgtgcgcc acaatattta tatgcaagct
      601 atgattccgt ttctttactt cgtgtcaaaa aagatactca ggaaccgacg cgtgaggtat
      661 ttgaacagga attggagaat tttgcaaatt cagaacagag tttaatagct agaagaattg
      721 tagagccgag taaggatggg acgactcact ttatttatgc aacttatggt cagggaactt
      781 taccaaaaga attccaagaa gctagccaag aaagtcgtga acgtagtgat ccgctaaata
      841 gttatctcct tttgtcaggt tccttgacga aagaaaagct tgccgataaa ttaggagatt
      901 tgggttataa agcaagtgct gaccgaaaga taccgcccta ttttcttgct tttcgaatat
      961 tactaaatcc ccttatttta attagtttag caatatttgg cttatctttc tttgctttag
     1021 tgattatcac tcggattaag gaaatgagag cagcaggtat aaaactcttt tctggtcaga
     1081 ctctcttatc catcatgggg cattctttat ctactgatat caaatggctc cttctatcag
     1141 ccctcctttc cttcctaggt gggggagtcg ttctttttag tcaaggtttg ttttatccta
     1201 tcttgttagc cacctatggt tttgggatta gtttctatct gttgttttta ttggcgattt
     1261 caattttact aatgctcctt tatctaatga gtttgaatta caaagcatta gttcccgtta
     1321 ttaaggggag attacccctt aaacgcctga tgattttaac cctattgtgt cagttggttg
     1381 ctgtctttac agtaggatac gctgttaaga caggtttgac gtcttaccaa cgattgaaag
     1441 aacttgaaat ttcaaaacaa gcatggcagg atagagcaga ctattatcaa atttcttttg
     1501 gcttaggtga tagaggaaaa gatatagaaa atcagagcaa gtggtatgcc tttgccaagg
     1561 aagcaatcga agaagaacaa gctctttatg taaaggataa tctgctccat tttgccaatc
     1621 cacaaggaaa aaatgaacag ggagagacac tggataccta tagtccagat gctaatacgc
     1681 tctatgttag tcccagttat ttggacaagg aaaaggtcgt ggtagatgct gagaccaaac
     1741 agaagttagc ccatctccaa aaaggtgagt ttatcctctt gctcccagaa catttgcgct
     1801 ctcgagaagc agaacttaag aaagtttttg aagaaagatt gagttattat ggaaaatctg
     1861 gtgaggaggc aagtgctcct ttggattatg agatgaaagc gcacgttagt tatctttcaa
     1921 tgggagaaaa gcggtttgtt tataataacg gtgagaatcc cgtatccact cagtatttga
     1981 ctgatccgat tttagtggta ttcacgccga cttctacagg tgatagtttt atatccttat
     2041 ctagttggtc tatcaatgct ggaaaacaac tctttatcaa aggatatgag agtgggctag
     2101 aactcttgaa gaaagctgga atttatgagc aagtatccta tcttaaagaa ggaagaagtg
     2161 tttatctaac tcgttataat gaagttcaaa ctgaaacagc aactttaatc ttaggagcta
     2221 ttgtggggat agctagttcc ttgttactat tttattctgt caatattcta tatttcgagc
     2281 aattccgccg agatatcttg attaaacgaa tttcaggttt acgatttttt gaaacacatg
     2341 ctcagtatat ggttagccaa tttgccagtt ttgtatttgg tgctagtctc tttattttaa
     2401 gcagtcgaga cttggtgatt ggcttgctca ctttattggt ctttctagct agtgcagttt
     2461 tgacgcttta ccgtcaagcg cagaaagaat ctcgtgtttc tatgacaatt atgaaaggaa
     2521 aataggatga ttgaactaaa gaatatatct aaaaaatttg gaagccgtca gctattttca
     2581 gatacgaatc ttcattttga aggtgggaaa atttatgcct taatcggtac aagtggctgt
     2641 ggtaagacaa cactcttgaa tatgattgga cgattggagc catatgacaa agggcaaatc
     2701 atctatgatg gcacttctct taaggacatc aagccttctg ttttctttag agattacttg
     2761 ggatacttat ttcaagattt tggcttaatt gaaagccaaa ccgtcaaaga gaatctcaat
     2821 ctgggtttag ttggtaaaaa gttgaaggaa aaagagaaaa tctctttgat gaaacaagct
     2881 ctaaaccgtg taaacctctc ttatttggat ttgaagcaac ctatatttga gttatcagga
     2941 ggagaagcac aacgtgttgc actagcgaag ataattttaa aggatccgcc tttgattctt
     3001 gcagatgaac caaccgcttc cttagacccc aaaaactctg aggaattact ttccatccta
     3061 gaatctttaa aaaatccgaa tcggaccatt attattgcga cccacaatcc tctgatttgg
     3121 gagcaagtgg atcaggtcat tcgagttacc gatttatcac atagatgata tggtaagatt
     3181 cagttagaag aaagagtcac aaacacactt tgtggctttt ttatttccat aaaaatggta
     3241 aaatagtagg agtagaaatg gagttcgaga catgaaagta atagatcaat ttaaaaataa
     3301 gaaagttctt gttttaggtt tggccaagtc tggtgaatct gcggctcgtt tgttggacaa
     3361 gttaggtgcc attgtgacag taaatgatgg gaaaccattc gaggacaatc cagctgccca
     3421 atgtttgctg gaagaaggga tcaaggtcat tacaggtggc catcctttgg aactcttgga
     3481 tgaagagttt gccctcatgg taaaaaatcc aggtatcccc tacagcaatc ccatgattga
     3541 aaaggctttg gccaagggaa ttccagtctt gactgaggtg gaattggctt atttgatttc
     3601 agaagcaccg attattggta tcacaggatc gaacggtaag acaaccacaa cgactatgat
     3661 tggggaagtt ttgactgctg ctgggcaaca tggtctttta tcagggaata tcggctatcc
     3721 tgccagtcag gttgctcaaa tagcatcaga taaggacacg cttgttatgg aactttcttc
     3781 tttccaactc atgggtgttc aagaattcca tccagagatt gcggttatta ccaacctcat
     3841 gccaactcat atcgactacc atgggtcatt ttcggaatat gtagcagcca agtggaatat
     3901 ccagaacaag atgacagcag ctgatttcct tgtcttgaac tttaatcaag acttggcaaa
     3961 agacttgact tccaagacag aagccactgt tataccattt tcaacacttg aaaaggttga
     4021 tggagcttat ctggaagatg gtcaactcta cttccgtggt gaagtagtca tggcagcgaa
     4081 tgaaatcggt gttccaggta gccacaatgt ggaaaatgcc cttgcgacta ttgctgtagc
     4141 caagcttcgt gatgtggaca atcaaaccat caaggaaact ctttcagcct tcggtggtgt
     4201 caaacaccgt ctccagtttg tggatgacat caagggtgtt aaattctata acgacagtaa
     4261 atcaactaat atcttggcta ctcaaaaagc cttgtcagga tttgacaaca gcaaggtcgt
     4321 cttgattgca ggtggtttgg accgtggcaa tgagtttgac gaattggtgc cagacattac
     4381 tggactcaag aagatggtca tcctgggtca atctgcagaa cgtgtcaaac gggcagcaga
     4441 caaggctggt gtcgcttatg tggaggcgac agatattgca gatgcgaccc gcaaggccta
     4501 tgagcttgcg attcaaggag atgtggttct tcttagtcct gccaatgcta gctgggatat
     4561 gtatgctaac tttgaagtac gtggcgacct ctttatcgac acagtagcgg agttaaaaga
     4621 ataatatgaa aaaaattgtc tttacaggtg gggggacggt tggacacgtt accctcaatc
     4681 ttttgttaat gcccaagttc atcgaagatg gttgggaagt ccactatatc ggggacaagc
     4741 gtggtatcga acaccaagaa atccttaagt caggtttgga tgtcaccttc cattctattg
     4801 cgactggaaa attgcgtcgc tatttctctt ggcaaaatat gctggacgtc ttcaaagttg
     4861 gttggggaat tgtccaatcg ctctttatca tgttgcgact gcgtccacag accctttttt
     4921 caaagggggg ctttgtctca gtaccgcctg ttatcgctgc gcgtgtgtca ggagtgcctg
     4981 tctttattca cgaatctgac ctgtctatgg gcttggccaa taaaatcgcc tataaatttg
     5041 cgactaagat gtattcaacc tttgaacaag cttcgagttt ggctaaggtt gagcatgtgg
     5101 gagcggtgac caaggtttcg gacaaaaaca ctccagaacc agatgaattg gtggatattc
     5161 aaacccactt taatcccaaa ttgccaactg tattgtttgt tggcggttct gcaggcgctc
     5221 gtgtctttaa ccaattggtg acagaccata agaaagaact aacagagcgc tacaatatta
     5281 tcaatctaac tggagattct agcctgaatg agttgaggca aaatcttttt cgtgttgact
     5341 atgtgaccga tctctatcaa cccttgatgg aattggctga tattgttgtg acacgaggtg
     5401 gtgccaatac gatttttgag ctcttggcga tagcaaaatt gcatgtcatt gtgccgcttg
     5461 gtcgtgaagc tagtcgtggt gaccagattg aaaatgcagc ttactttgta aaaaaaggct
     5521 atgcagaaga ccttcaagaa agcgatttga ccttggatag tttggaagag aagctttctc
     5581 acttactaag tcacaaggaa gattaccaag ctaagatgaa agcttctaag gaattgaaat
     5641 ctctagcaga tttttatcaa ttgttgaaaa aagatttatc ataaggaaag taaatgtcaa
     5701 aagataagaa aaatgaggac aaagaaatcc tcgaagaatt gaaagagtta tcagaatggc
     5761 agaaacgaaa ccaagaatat ctaaaaaaga aggctgaaga agaagcggct ctagctgagg
     5821 agaaggaaaa ggaaagacaa gctcggatgg gagaagaatc tgagaagtca gaggacaaac
     5881 aggaccagga gagtgaaaca gaccaggaag attcagaatc agctaaggaa gagtctgaag
     5941 aaaaagtagc atcctcagag gctgacaaag agaaagaaga gaaagaagaa tcagagtcta
     6001 aagagaagga ggaacaggat aaaaagcttg ctaaaaaggc tacaaaggaa aaaccagcca
     6061 aagcaaagat tcctggtatc catatcttgc gagccttcac gattttattt ctaagtctgc
     6121 ttttattgat tgtctctgcc tacttgctca gtccttatgc gaccatgaaa gatattcgtg
     6181 ttgagggaac ggtgcaaact acagctgatg atattcgaca ggcttcaggc attcaggatt
     6241 cggattatac gattaacctt ctgctagaca aggcaaaata tgaaaagcag attaagtcta
     6301 actattgggt tgaatcagct caacttgtct atcaatttcc aactaagttc actattaagg
     6361 tcaaggaata tgatattgtg gcctactata tttctggtga aaatcattat cctattcttt
     6421 ccagtggtca gcttgagact agttctgtga gtctgaacag tttaccagaa acttatttat
     6481 cagttctctt taatgatagt gaacaaatca aggtttttgt ctcagaactt gctcaaatta
     6541 gcccagaact caaggcgact atccaaaagg tggaattagc cccaagcaag gtgacatccg
     6601 atttaattcg attgaccatg aatgattcgg acgaagtctt ggttcctcta tctgaaatga
     6661 gtaagaaact gccatattac agtaagatta agcctcaatt gtcagaaccg agtgtggtcg
     6721 acatggaagc tggaatctac agctacactg tggcggataa attaattatg gaagctgagg
     6781 aaaaagccaa acaagaggcc aaggaagccg agaaaaaaca ggaagaagaa cagaaaaaac
     6841 aagaggaaga gagcaattga aatcaaacga cccagcgctc attgcgtcgc taggtttacc
     6901 ttttctctta tagttcttta gtgaccatgt ttttacttga caagtgctag tagaaataat
     6961 agaataatag aaaaccttta aagcagtcca gagaggcagc taaggttaga cggtgaaagg
     7021 gtggagacta cccatttttc gtggaacctt gctgttggca ggttcctttt ttcgtggctt
     7081 ctgttggcca gactctctca ctagtaaagg taaaaggaga aacctatgcg agaacatcgt
     7141 ccaatcattg ctcttgattt tcctagtttt gaggtggtca aggaattttt agctcttttc
     7201 ccagcagaag aaagccttta tctcaaggta gggatggagc tttattacgc agcggggcct
     7261 gagattgtgt cctacttaaa aggtttgggt catagtgtct ttttggatct caaacttcat
     7321 gacattccca atacagtcaa gtcagcaatg aagatcctat ctcagcttgg tgtggatatg
     7381 accaatgttc atgcggctgg tggtgtagag atgatgaagg ctgcgcgtga aggtcttgga
     7441 agtcaagcta aattgatcgc tgtaactcag ctcacatcaa cgtcagaagc tcagatgcag
     7501 gagtttcaaa atatccaaac cagtctgcaa gagtctgtga ttcactatgc caagaagaca
     7561 gctgaagctg gcttggatgg tgttgtttgc tcggctcagg aagtacaagt catcaagcag
     7621 gctaccaatc cagattttat ctgtctgaca ccagggattc gtccagctgg tgttgcagtt
     7681 ggagatcaaa aacgagtcat gacacctgct gatgcctatc aaatcggcag tgactatatc
     7741 gtagtgggac gtcccattac ccaagctgag gatcctgttg cagcttatca tgccatcaag
     7801 gatgaatgga cacaggactg gaattaaaga actagattag aaaaataaaa ggagaatacc
     7861 atgacacttg ctaaagatat cgctagccac ctcttgaaaa tccaagccgt ttacctcaaa
     7921 ccagaggaac ccttcacttg ggcatctggt atcaagtcac cgatttacac tgataatcgt
     7981 gtgacactag cctatccaga aactcgtacc ctaattgaaa atggttttgt ggatgctatc
     8041 aaagaagcct ttcctgaagt agaagtgatt gcaggaactg caacagcagg gattccacac
     8101 ggagccatta ttgctgataa gatggacttg ccttttgcct acatccgtag caaaccaaaa
     8161 gaccatggag ctggtaatca aatcgaaggt cgcgtagctc aaggtcaaaa aatggtagtg
     8221 gttgaagacc ttatttcaac gggtggttca gttcttgaag ctgtagcagc agccaagcga
     8281 gaaggagcag atgtgcttgg agttgtagcg attttcagct accaattgcc aaaagcagat
     8341 aagaactttg cagatgctgg tgttaaactt gtgacgcttt caaactatag cgagcttatc
     8401 catctagccc aagaagaagg ttacatcacg ccagagggcc ttgatcttct aaaacgcttt
     8461 aaagaagacc aaaaaaattg gcaagaaggt taggtcagta agataaagag agacgaggct
     8521 accgagcctc ttttaccatt ttatttaaaa tatgacaata ttttaaataa aatgattgac
     8581 aacgctttct tttattgata taatgaaaat gtaatatgta tcaaattgat caatcaacta
     8641 tcttgtttac cacttcttag gaggacgatg tcatgaaaag aagaaaaata tattcctttt
     8701 ttgcgtagtt acaattgcat ctagtttgtt tctccctaca gttttagcta gacagattgg
     8761 aaattatgat ttaacgttgc cgcgttgggg ttcggataca actagtgagc ttgagaaaga
     8821 aaacgcctct gctggaatta ataataatga cagcactggt ggcggtaaaa ggttaaatac
     8881 ctctattcgt agcgcctata gtgggtcaga tattaccccg gtatattcat tggggtctgg
     8941 ctctaggatt gtcatgtact ataatggagg tggtgacaat tatattggtt ctggtactag
     9001 attagctatg gcgccacaat ttagaaatca tgtaagaatt catacttcag gttcttggag
     9061 tccagattct tattaactta cttgtcagag taagccttaa agatggttga ttgtgggtgt
     9121 agcatgaaaa aagaatgcta caccctattt ttattataag gaggagtaag gatggaattt
     9181 ttcatttgta atcttgtacg agtcgttcaa tcacctcgat tttatatgtc tttatttttg
     9241 acccttcttt gcatgagttt aggaaatttc cttgctttca atggtattta taaaattgaa
     9301 ggtttatcga ttttttttgc cgcttcttct attcgaggat tttcaccgat tagcctagta
     9361 gctgcactta tctgtacact gccctattct agtcagataa tagaggatgc tgagagtcat
     9421 tttctaacag cacaattgtg tcgaatttct aaaaagaagt atctggctat tgtgggtagt
     9481 actgcaatta tttcttcttt tctagtcttt tttctcccct atttattatt attaggaatt
     9541 aatcttttag tgactcctta tcaggaaatt tatattggag attatagtgg tgccttaaaa
     9601 gaattatttg attccaatca gttgctctat agtcttgtga cgactctctg gtatggagtt
     9661 tggggcgctg tgttctctat ttttggacta gctagtgctt tgctagtgaa gaaaaaaata
     9721 ggagctattt tcatcccagt tgcctatatg atggttggtg gtattttttg ggctatttta
     9781 gggctatctt acttagaacc tgtgacaaca ttagctttgg gatatcagaa agatatcagt
     9841 ctttccttag ttagtgggca tcttgctttt attttatttg ttagttgttt ggttgtttat
     9901 ggtacatttt ttctacattc agaggactat gtataatgaa acaatttgtt caattttata
     9961 aaaaagattt cttagcagta ttggtttatt ttatattact gctatcctgt gttttatcta
    10021 gtacagtata tttattgcgc tgtcgccaat attcaatcca tccaaatgta ttagaatgga
    10081 tcttagtctt acttcaagat atgacgactg gagtatactg ctttccgttc acatatatat
    10141 tgttcttttt ttatttgatg aataactatt ttaataggtt ggagtgtcgc attcgtctga
    10201 aatcaattaa gcactttacc agttttagtt tcaaattagc agctcttagt acggggattt
    10261 ggacggcgac tttattttta ttgatttttc tgattgcatt tagtaatggt tttagcttct
    10321 ctttggagat aaaggaggtt gattttttaa gagaatttta tggtataagt attgcaaaca
    10381 atgctagttt ctttatagga ttttttttct cttatatagc atactatttc tttttatcct
    10441 tacttactat tagcagtttt tcttggttta aaaaatcaaa catgagctta gtatttctgt
    10501 ttactttttt atttgtagaa tccttattct ggatttatca gttggacaat gggataattg
    10561 gattattgcc aatttttcag tatatggtaa attccaatcc gtatgcattg atttattggc
    10621 ttacattact atctatcata attccattga ctgtattttc tgttcataga aactggagga
    10681 gagtgtaaaa gttggaaatg ggaaagttaa gtagtcacat gtggaggttg aatcagataa
    10741 tctataccaa gtacttttgg ggttatgttc ttttttggat attgatttgt ttaggattat
    10801 ggtattggtt agaaggaaat gatagacttg ttatagaaat tttaaaaggg cctaatctga
    10861 gtcaaaactc ttttttagtc ttatctatat ggttgcttca ttggtttatt attcatacat
    10921 tttttctagc agttgtatat cgtagaagag catccgattt ctttatggaa gtgattcgat
    10981 tttcttctat taagctctgg attaggtatc agatttggac ctgttttctt tatggactca
    11041 ttttaatcat ggtaaaagtt ctagtgattc aatttatgtt acagttacca aactgggata
    11101 taggagtttt gtttatagtt gattttttga atgcttgtgt gttagtcttg ttttgcttta
    11161 tgttatacgc actaggagcg aatgtacaaa tgaactttgc ttgcgttagt ttctttttac
    11221 tcatgattgt gtttggtggt ctatttgtag gaaatcgaac taattatcta ttttatattt
    11281 taaatcgagg gaatggagat ataggacgag atttatttct tcagttgcta tttttagtct
    11341 ttctttttaa aagcattttc tatttcactc gtcaaaagag gaggtttata gaatgaatga
    11401 aataattaca ttaaaaaata ttcagttgga attaaaaaaa acatgtgttt ttcaaaacct
    11461 taattttagt tgtaaacagg gggaaattat aggaattact ggtgcgaatg gctcagggaa
    11521 aagtgtattg tttaaattaa tagctggttt atatagtccg tcttatggag aagtgttaat
    11581 caatggggaa aatattgttc ctgagagaaa aattccagct aatttgggag ctttgattga
    11641 agaacctggt tttataaatt attatagtgg ctttaagaat ttacaatatt tggcaagcat
    11701 acgaggagta gttggtaatc aggaaatcaa tgatacactg aaaatagttg gtctatatga
    11761 gcaaaaagac cagaaagtta aaacttattc gctaggtatg aggaaaaagc tagggattgc
    11821 tcaagcaatt atggagaatc cctctattct tttactagat gaacctatga atgccttgga
    11881 taaatcaagt gtagaaaata tgagaacatt gtttagaaag ctctctagtg aaaaagggac
    11941 aacaattttg attgctagtc atagtgaaga ggatattcgt atcttatgtg ataaagtata
    12001 tgcaatagaa gataaagtat gtacactgtg ttcagattga acatcttaga tagactcagg
    12061 atgttatagg taaaatctta aaaagggatt ggatcttaaa atccagttcc ttttaagagt
    12121 taatgactaa tcaacttttc caccttcaac aaccaggtca tctgctttag cagcgtcacc
    12181 gtaggttagg tgaagtgttt tttcataggc cttgtggaag aagttttcct tgcctaattt
    12241 ttcaatatct ttattgatga agtctagcaa ttcttggttg cctttttgaa ctgctgccgc
    12301 aatggtatcg ggatcaccga gggaagtaat tcctacttca aatcctttat tttcaagcgc
    12361 ccaagctaga acttccgtat tgtcagttga aaaggcatct ccacgtccgt caagaagagc
    12421 ttggtaagag tcactgtatt ggtcgtattt ttggagtttg atttctggat gattcttttc
    12481 aaaataagtc tcagcagtcg ttccttttgt gacaattaag gttttacctt caagttgttt
    12541 gacgtctgta atgagaccag tcttaggtga tacgacaccc agagaaactt tcatatatgg
    12601 aagggcaaaa tcaacttgtt tcttacgttc gtcagttact gtaaagttag caagagtaat
    12661 atctaccttg tttgaaatca agtattccgc acggttggca gcatcgactg aaatgtattt
    12721 aaccttgaca ccaaggtctt gagctagttg gttccctagt tcaatatcgt agccttggta
    12781 agaaccatca ttgtcaacgt agccaaacgg ttttttatct ccaaacacgg cgattcgcag
    12841 ttcaccgctt tttttgattt catcgatagt gcgagctttg gcagttgttt ttccagagga
    12901 tgaaccagcg tttccacctg agctacaagc agtgataaag ataagggcaa aggcaagtgc
    12961 taaaacagtt aagagtggtt tgaatagttt cataagaatc tcctttatag atatgagccg
    13021 aattggctaa agtcaaagac gtttaaaaat tcctgggctc gtttggtttg cggattggta
    13081 aagaaggctt gagctgttcc ttcttcagcg attttccctt ggtcgaggaa gataatccgg
    13141 tcagcaatgg cttgggcaaa ctgcatttcg tgggttacta aaatcatggt acggccttct
    13201 tgggccaaat cattgataag ttccagcacc tcacgcacca tttctggatc cagcgaagca
    13261 gtcacctcgt caaaaaggat gatttctgga tgcattagga gggcacggac aattgcaaca
    13321 cgttgcttct gtccaccaga taattgacgg gcaaagcaaa gctatgttgt ttatccagta
    13381 aaccgacacg atctagtaat tgcaaagctt cttccgttac ttctttcttg tcccttcctt
    13441 gagctttgat agggcctagg atgaggtttt gtaagacatc cagatgggga aagagttcat
    13501 aactttgaaa gaccatgcca atcttttggc gaactaggtg aaaatctttt ttattttcaa
    13561 cgatagactg accatccaga agaatatctc caccttgaat actttctaag ccgttgaggc
    13621 aacgaaggag ggtacttttc ccacaaccaa atggccctag gatgacaaca acttcccctt
    13681 ttttgatttc tagagaaagt ccttggagga tgggattgtc tccgaaggat ttttttagtt
    13741 ccttgatttc taagatagtt tcagacattt agtttctcca atgtttttct aagtgagtgg
    13801 atagtttgga aatagggtag caaactgcga aatataagac tagaatggtt ccataaatcc
    13861 aaaatgaagc agttggggat ggtcaggcga ttgctatcga tgatttgttg tccaactttg
    13921 gtcacttcca caaccccaat caaaacaact aatgaagtgg ttttaatcat ccgagtgaca
    13981 agattgatag cctgcggtag cagtcttctt aagacttgtg ggatgatgat gtggtagtaa
    14041 agttgaacat tagtcaagcc gagtgcctat ccactttcaa actgatgttt agggagagaa
    14101 gtgatagctc cacgtaccaa gtctcccatt tcagctgttc cccagagggt aaaaatgata
    14161 atagctgaag tctcacctga gatattgata ttaaagtttc gagccaagcc aaagtaaacg
    14221 atgaagagta gcaccagctg gggcatgata cggataaatt ccagatacaa tcgtgttaaa
    14281 aatcgtatga ttctagaatg ggaggtcatg atgattccca tgactgttcc gaacatcatg
    14341 gataagagga cagacaggat ggatatccca atcgtaacgc ccaacccctg taagattctc
    14401 aggagattat ttccttgaaa gagtacttgg attcccgaat cctgcatggc gggtcctcct
    14461 ttctatccag ctaaagacca gtgagatggg tagcagcatg atcagataag caactaccaa
    14521 catagctagc gcaatgtctg tctcatagta gagaccaatc aaatccttgg cgacgtacat
    14581 gaggtcggcc aaagccactg ctgagaaaac agaggttttc ttgataagga aaatgacatt
    14641 ggcactaaag gaggggagta ccaccgctgt tgcttgcgga agaaccacat agcgaaagac
    14701 ctgtagaggt gtcagaccaa tagcgaggcc aatctcctgc tgggtttgac tgatggcttc
    14761 cagcccactt cggaaagatt ctgccatata ggagcctcct aaaaagacaa gtccaagcgt
    14821 tgcacagact tctgaagata ggacaatccc gattcgggga agaccgaagt agagaaagaa
    14881 gagttgaatc aaaaggggcg tattacgtga caattcaatg taggctgtcg ctacttgcgc
    14941 taaaacaggg attcgataat gtcggatgat actaacgatt aaaccgagca gaaaggatcc
    15001 caaaattccc caaactgcaa tatgcaaggt cagaaagaat gccttttgat atagtggtag
    15061 atattgttca acaatggatc aatccaaaaa tagaacctcc catctagaaa taatacagtt
    15121 attgtagcac ttaaaatctt ctttggataa tatctatttt ttattgccgt tataaggatt
    15181 tttatcatag acataaaatt tctgaaattt ccaaacaaaa tatttgaaaa gttttgaaaa
    15241 aagagttaat atatttttat aatatacaaa gtaaacgctt acttattaag gaggacattt
    15301 tatgtcatac aaaacaagca atgcagaagg tcatgtagat ttcatcaata cctatgattt
    15361 ggagccaatg gcgcaacaag ttattcctaa agcagcattt ggctatatcg ctagtggggc
    15421 ggaagatact ttcacttctt tccagtgatt ttagcgtcag gttcttttta gtttttaaag
    15481 attatccgtg aatttcttgc ttatttatga taaaatggga gtatcgcaaa aaatgactca
    15541 tcgtattcaa ttttgagtaa aactaggagg atcccatgtc tacagaacat atggaagaac
    15601 taaatgacca gcagatcgtt cgccgtgaaa aaatggctgc gctccgcgaa caaggaatcg
    15661 atcctttcgg aaaacgtttt gaacgtactg caaattcaca agaattaaaa gataaatatg
    15721 ccaacctcga taaagaacaa ttacacgata aaaacgaaac agctactatc gcaggacgct
    15781 tggtaaccaa acgtggtaaa ggaaaagttg gttttgccca ccttcaagac cgcgaaggcc
    15841 agattcagat ctacgttcgt aaggatgctg tcggtgaaga aaactacgaa atcttcaaaa
    15901 aagcagacct tggtgacttc cttggtgtcg aaggtgaagt gatgcgtacg gatatgggag
    15961 aactctctat caaggcaacc cacatcacac acttgtctaa ggctcttcgt cctcttcctg
    16021 agaaattcca tggtttgaca gacgttgaaa caatttaccg taaacgttac cttgacttga
    16081 tttctaatcg tgaaagcttt gaacgctttg tcactcgttc aaaaatcatc tctgaaatcc
    16141 gtcgttacct tgaccaaaaa ggattccttg aagtggaaac acctgttctt cataatgaag
    16201 ccggtggtgc tgctgcccgt ccatttatca cccaccacaa tgcccaaaac attgacatgg
    16261 tgcttcgtat cgcgactgag cttcacttaa aacgccttat cgtgggtggt atggaacgtg
    16321 tctatgaaat tggccgtatc ttccgtaacg aaggaatgga tgctactcat aaccctgagt
    16381 tcacttctat cgaagtttac caagcttatg cagacttcca agatatcatg gacttgacgg
    16441 aaggcattat ccaacatgct gctaaatcag ttaagggcga tggcccagtc aactaccaag
    16501 gtactgaaat caagattaac gaaccattta agcgtgttca tatggtggat gctatcagag
    16561 aaattactgg tgtcgatttc tggcaagaca tgactttgaa agaagctaaa gctatcgctg
    16621 ctgagaagaa agttccagtt gagaaacact acactgaggt tggtcacatc atcaatgcct
    16681 tctttgaaga gtttgttgaa gaaactttaa tccaaccaac ctttgtctat ggacatccag
    16741 tagctgtatc tccactcgct aagaaaaatc ctgaagacca acgctttact gaccgtttcg
    16801 agctctttat catgactaag gagtacggta atgcctttac tgagctcaac gacccaatcg
    16861 accaacttag ccgttttgaa gcccaagcta aagctaaaga acttggtgat gatgaagcga
    16921 caggcatcga ctatgactac atcgaggctc ttgaatacgg tatgccacca acaggtggtt
    16981 tgggaatcgg tatcgaccgt ctctgcatgc tcctcactga tacaacaact atccgtgatg
    17041 tattgctctt cccaacaatg aaataaattc
//
LOCUS       DAVLDI010000050        15828 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLDI010000050 DAVLDI010000000
VERSION     DAVLDI010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15828
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.050"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(1..255)
                     /locus_tag="VXD01_001713"
                     /pseudo
     CDS             complement(1..255)
                     /locus_tag="VXD01_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            380..838
                     /locus_tag="VXD01_001714"
     CDS             380..838
                     /locus_tag="VXD01_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV0602067.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            851..1459
                     /locus_tag="VXD01_001715"
     CDS             851..1459
                     /locus_tag="VXD01_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602068.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            1530..1862
                     /locus_tag="VXD01_001716"
     CDS             1530..1862
                     /locus_tag="VXD01_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602069.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            1873..3288
                     /gene="ply"
                     /locus_tag="VXD01_001717"
     CDS             1873..3288
                     /gene="ply"
                     /locus_tag="VXD01_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV0602070.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            4169..4885
                     /locus_tag="VXD01_001718"
     CDS             4169..4885
                     /locus_tag="VXD01_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0602071.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEALETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            5009..5479
                     /locus_tag="VXD01_001719"
     CDS             5009..5479
                     /locus_tag="VXD01_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV0602072.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQIQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            5496..6317
                     /locus_tag="VXD01_001720"
     CDS             5496..6317
                     /locus_tag="VXD01_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602073.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQGTNLDELWQPA
                     SMMMGMPFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLM
                     RTTNDITQVQMLITMGLQVVTCGPIMAIWAIGKILGHSEYWLWAVLVAVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM"
     gene            6324..7355
                     /locus_tag="VXD01_001721"
     CDS             6324..7355
                     /locus_tag="VXD01_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0602074.1"
                     /translation="MDFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            7421..7783
                     /locus_tag="VXD01_001722"
     CDS             7421..7783
                     /locus_tag="VXD01_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV0602075.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            7780..8283
                     /locus_tag="VXD01_001723"
     CDS             7780..8283
                     /locus_tag="VXD01_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0602076.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSAGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            8397..8843
                     /locus_tag="VXD01_001724"
     CDS             8397..8843
                     /locus_tag="VXD01_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0602077.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            8849..9523
                     /locus_tag="VXD01_001725"
     CDS             8849..9523
                     /locus_tag="VXD01_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602078.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVSLMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGTAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            9779..9967
                     /locus_tag="VXD01_001726"
                     /pseudo
     CDS             9779..9967
                     /locus_tag="VXD01_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647592.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
     gene            10217..10516
                     /locus_tag="VXD01_001727"
     CDS             10217..10516
                     /locus_tag="VXD01_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV0602079.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            10513..10830
                     /locus_tag="VXD01_001728"
     CDS             10513..10830
                     /locus_tag="VXD01_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV0602080.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     SNPEFTFIRVDRDQYIDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            10846..11472
                     /locus_tag="VXD01_001729"
     CDS             10846..11472
                     /locus_tag="VXD01_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV0602081.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKDKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            11505..12266
                     /locus_tag="VXD01_001730"
     CDS             11505..12266
                     /locus_tag="VXD01_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV0602082.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            12344..12739
                     /locus_tag="VXD01_001731"
     CDS             12344..12739
                     /locus_tag="VXD01_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV0602083.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            13009..13293
                     /gene="groES"
                     /locus_tag="VXD01_001732"
     CDS             13009..13293
                     /gene="groES"
                     /locus_tag="VXD01_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV0602084.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            13309..14931
                     /gene="groL"
                     /locus_tag="VXD01_001733"
     CDS             13309..14931
                     /gene="groL"
                     /locus_tag="VXD01_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV0602085.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISNRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(15030..>15828)
                     /locus_tag="VXD01_001734"
     CDS             complement(15030..>15828)
                     /locus_tag="VXD01_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV0602086.1"
                     /translation="HDFSCLPEIMSWDEYAFTKGKMSFIAQDFNNLNIITVLEGRTQA
                     VIRDHFLKYDRAVRCRVKIITMDMFSPYYGLAKQLRFHIVQHLSRAMSRVRVQIMNQF
                     HRKSHEYKAIKRYWKLIQQDSRKLSDKQFYRPTFRMHLTNKEILNKLLSYSEDLKHHY
                     QLYQLLLFHFQNKEPEKFFGLIEDNLKQSHPIFQTVFKTFLKDKEKIVNALQLHYSNA
                     KLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         4697 a         2881 c         3642 g         4608 t
ORIGIN      
        1 gatagcgcat ggttacaggc tttatcttca actgttagcg gcttgagttt gctggattta
       61 cgtggagttt gtgcttgagg atatatcttc atgagccctt gataaccact gtcagccaag
      121 attttaccag cttgtccgac ttttttgata agctgttttt aatccagcta acatctcttc
      181 aaaagtggta cgctgaacac taacaagacg cttaaatcgt gcatcagtta gttgtttact
      241 tgcttcatca ttcatagaac tactatacca tattttgttt cgcaggaagt ctaataagtt
      301 atagtccagt ttttactata ctttgatatt caaatatgtt atactatggt tatcaaagta
      361 aatgaaagga gttacgaata tgacgccaga agaaatgtac ctgacagagc gattagacgt
      421 acagatagct cattttttaa agaaaagcgt tcaacatcgt agacgctata aggtattaaa
      481 aataacagaa atcgtggcag gtttcctcat agctgtcttt tgtgctattc ctatgccagg
      541 tgatcgctac cgtttgattt cggttgcctt atccagtctc ggcttgctgt gtgaggggat
      601 tatcaatttg tataatgcaa aggaaaattg gatttcttac caaaaaactg cgcaactcct
      661 ggagaaagaa aaattcctct atcaatgcca aacggagaaa tatgcaggaa agaccaaggc
      721 ttttgcccta tttgtcaaga catgcgaagg tcttatctca gaggagatta accagtggga
      781 aagtatccag tcaaaagaag tggcagctag tgcagatgct ccagttaaaa aagagtagga
      841 ggtagaggaa atgtctcaat ccagctacct gtcgcccttg ctctggttaa aaaaagaagc
      901 cgataaggaa aagatgagcg cgacccagtg ccagatattt ttcttttact atcaaatgtt
      961 tgagctctta tttgctagag aaagcgacat gaaagactta tgtctgggaa cgaaaggttt
     1021 ttatttctcg cagttagaga aaaatttgct ttctggagtt tcccgatttc taaaaaactt
     1081 ggaggggaaa gtaactctca aggctaacca agaagtatca gctcgcaaag ccctttttct
     1141 agccttgaca actagccaat cagattggca ggagttagct cctgtttttg atttttatca
     1201 gactatcggg aggcttgaaa atccttctct cttgagttct caggacagac aacatctgat
     1261 gtggatttac cagtcagctt tggagaagga ttatattgtc aaggttattg gcgacaagca
     1321 ttttgtattg aagagacaag atgctactaa attgacagcg cgccaaactc aaactttgga
     1381 aattctgagt caatcagaag acttggtcaa tcctgtctat gttacattag gagaaaaggg
     1441 ggtgctcttg cttgattaag agaggagatg ttgtagctct ttatttgcct tttccgacta
     1501 ttagtagcga tttggctgtg aagaatcata tgtatatctg tattgacaac agcatgacta
     1561 aaaacaaaga gttggttaaa aatcagacct tcaaaccagc tctcttgacc agacgtttgg
     1621 tcaagaactt tatgatagaa gagccggatc tagctcgtaa tccttttaca agaccaacct
     1681 tgattgactt agataaggta tttatgttgg ataatacggt tattccgact tcttatctag
     1741 ccagacggcg acgcaatgtc tcagaagaat tgtacgagga aattttggat cacttagtcc
     1801 aaccacggct gatttcgctg aacaagtctg agtttatgca actcaatcca ggaacttatt
     1861 aggaggtaga agatggcaaa taaagcagta aatgacttta tactagctat gaattacgat
     1921 aaaaagaaac tcttgaccca tcagggagaa agtattgaaa atcgtttcat caaagagggt
     1981 aatcagctac ccgatgagtt tgttgttatc gaaagaaaga agcggagctt gtcgacaaat
     2041 acaagtgata tttctgtaac agctaccaac gacagtcgcc tctatcctgg agcacttctc
     2101 gtagtggatg agaccttgtt agagaataat cccactcttc ttgcggtcga tcgtgctccg
     2161 atgacttata gtattgattt gcctggtttg gcaagtagcg atagctttct ccaagtggaa
     2221 gaccccagca attcgagtgt tcgcggagcg gtaaacgatt tgttggctaa gtggcatcaa
     2281 gattatggtc aggtcaataa tgtcccagct agaatgcagt atgaaaaaat cacggctcac
     2341 agcatggaac aactcaaggt caagtttggt tctgactttg aaaagacagg gaattctctt
     2401 gatattgatt ttaactctgt ccattcaggc gaaaagcaga ttcagattgt taattttaag
     2461 cagatttatt atacagtcag cgtagatgct gttaaaaatc caggagatgt gtttcaagat
     2521 actgtaacgg tagaggattt aaaacagaga ggaatttctg cagagcgtcc tttggtctat
     2581 atttcgagtg ttgcttatgg gcgccaagtc tatctcaagt tggaaaccac gagtaagagt
     2641 gatgaagtag aggctgcttt tgaagctttg ataaaaggag tcaaggtagc tcctcagaca
     2701 gagtggaagc agattttgga caatacagaa gtgaaggcgg ttattttagg gggcgaccca
     2761 agttcgggtg cccgagttgt aacaggcaag gtggatatgg tagaggactt gattcaagaa
     2821 ggcagtcgct ttacagcaga tcatccaggc ttgccgattt cctatacaac ttctttttta
     2881 cgtgacaatg tagttgcgac ctttcaaaac agtacagact atgttgagac taaggttaca
     2941 gcttacagaa acggagattt actgctggat catagtggtg cctatgttgc ccaatattat
     3001 attacttggg atgaattatc ctatgatcat caaggtaagg aagtcttgac tcctaaggct
     3061 tgggacagaa atgggcagga tttgacggct cactttacca ctagtattcc tttaaaaggg
     3121 aatgttcgta atctctctgt caaaattaga gagtgtaccg ggcttgcctg ggaatggtgg
     3181 cgtacggttt atgaaaaaac cgatttgcca ctagtgcgta agcggacgat ttctatttgg
     3241 ggaacaactc tctatccgca ggtagaagat aaggtagaaa atgactagga gaagagaatg
     3301 cttgcgacaa aaagaggcga tgatctctct gcggatatct gaaagtttat ctcttgccta
     3361 gcgatttcca ttggagtatg ctcgtgatgt taaaatgagt ctatcaaaca ggatgtgtaa
     3421 aaaagtaaaa agggtagcca attccttgat atacagggga ttgattatcc tttacttgtt
     3481 ttagatgatt ggaaattcaa gaatgacacg tatcggaaat attttgctgt ttatatctaa
     3541 tacccattta tggaaaaaat gaaattaaat atgaacaaat caattgctag caatggttta
     3601 gaagtgccag tgtactagtc taacttctcc atcttgggaa cacgtaaatt atactcttcg
     3661 aaaatctctt caaaccaggt cagccctatc cgcaacttca aaacagtgtt ttgagcaccc
     3721 tgcggctagc tttctggttt gttctttgat ttttattgag tattagaggt ttgcttagaa
     3781 actcttctat tgatttctta gaatacaata gcgcctataa gaactgttgg atttcaaagt
     3841 atttacttga actatgatat gtctggagta gactgtcaac aaaaggtgca gtatgattgt
     3901 ttttgtcgct tatatctaca aacttcaaac agtaatttga gctgactttg tcaaacttgg
     3961 ctgaaacttt ctatttgcag ataatggtct agtttgtttt ttgaatgtgg atgagtgtct
     4021 gttgataaag atagaaaggc aagaccgtct tagcaggtaa agtgctatcc tagcttgatt
     4081 tgctaataaa atccatttcc tctagtgaaa atcaaaaaaa cttgtgttat aataagaaag
     4141 attaaaatgt gaaaaaagga gattcctaat gggacgtaaa tgggccaata tcgtagccaa
     4201 gaaaacggct aaagatggag ccaactctaa agtatatgca aaatttggtg tagaaatcta
     4261 tgtagcagct aaaaaaggtg atccagatcc agaatcaaac tcagctttga aattcgttat
     4321 cgaccgtgct aaacaagccc aagtgccaaa acacattatc gataaagcga ttgataaagc
     4381 caaaggaaac acagacgaaa cctttacaga aggacgttac gaaggttttg ggccaaatgg
     4441 ctctatgcta attgtggata ctttgacttc taacgttaac cgtacagcag ccaatgtccg
     4501 tgcagccttt ggtaaaaacg gcggaaacat gggcgcttca ggttctgttt cttacctttt
     4561 tgacaacaaa ggtgttattg tatttggagg tgaagatgcg gacgcagtct ttgagcaatt
     4621 gctcgaagcg gatgtggatg tggatgacgt agaagcacaa gaaggtacaa tcacagttta
     4681 cacagcgcca actgaccttc acaaggctat cgttgccctc cgtgagtctg gtattgaaga
     4741 attccaagtg actgaattgg aaatgattcc tcagtcagaa gtggaattgt caggcgaagc
     4801 ccttgaaacc tttgaaaaac tttacagcgt tcttgaagac gacgaagacg tccaaaagat
     4861 ttatacgaac gtagatgggt tttaatttaa cctatagaac atgatcctaa gtgagaaaat
     4921 cacttgggat ttttttaatc aagaaaatag ttctcataga aatttaatta ttctccagag
     4981 aactattttt atttagaagg gggagattat ggataaaccg atgttagtct ttaagcgttt
     5041 tggtcatcaa attcacctga tggtgcaaaa ggaagccaaa cgttgcggca ttgaatttat
     5101 gggtgggccg caaggtcagg ttgtgcattt tttggataat cgcgagaaaa accaagactt
     5161 ggtcttgatt aaagatatcg agcaggaact caatattacc aagtctgttg ctagtaatct
     5221 ggttaagcgt atagtgcaaa atggtttggt ggaattggag gcgagtcctg ttgataagcg
     5281 ggctaagttt gttcgtctga cggacaaagc acgttctcag atacaacagg ttaaggcttt
     5341 ttttgaacgc atagacaagc agttgatgga agacattgat gaagatgaat tactgatttt
     5401 tgagaaagtt ctcggtcaac tacaggcaaa tatcaaggga ataggaggag agaataaaga
     5461 aattagccaa aagaattagt agaaaagaat gggggatgat tttactagcc attctcttta
     5521 cttgcttttc ggtctatcta gagttggaag tgccgaccta tatctcgaaa attacggatt
     5581 tgctaggtag tcaaggaact aatttagatg agttgtggca gccggcaagc atgatgatgg
     5641 gaatgccctt tcttgccttc ttgtccgtag ttgcagttgg attttttgca tcccgagtgg
     5701 cggcttctta tactagtagg ctgagaagtg atatttttaa ccgagttttg gattactcgc
     5761 agacagagat taagaaattt tcaattccta gcctcttgat gcgtactacc aatgacatta
     5821 ctcaagttca aatgttgatt actatgggct tgcaagtggt aacgtgtggt ccaattatgg
     5881 ctatctgggc tattgggaag attttaggtc attcagaata ctggctctgg gccgtacttg
     5941 tggcagtgat tgtcaacgtc ctgatgacga ccgttttgat gacgctagcc tttccaaaac
     6001 agtccttgat tcaggggctg acagataaac tgaacagtat cactcgtgag agtttaacag
     6061 gtattcgtgt cgttcgtgcc tacaatgcag aggattatca aaatgaaaaa tttgcagcag
     6121 taaatgatga attgacccgt ttaaatttgt ttgtcaaccg tcttatggct attttgaatc
     6181 ctatcatgat ggggatttca agtggtttga gtgtggcgat ttactggatt ggggcctatg
     6241 tgattaacga cgctgctccg atagcgcgtc tgcctctctt tagtgacatg attgttttca
     6301 tgtcttatgc catgtaggtt gtcatggact tccttctcat gggagcactc ttcatcgttc
     6361 ttccccgaac tatggtctct gctaagcgga ttaatcaagt tttagatttg cattcttcta
     6421 tccaaaaccc tgttcaagta cagctgactg atgaaaactt caaaggtcag gtcgagttta
     6481 aggatgtgac cttccgctat gcggcaaatt cggaggcagt tattgaacat gttagcttta
     6541 aagcagaaac tggtcaaaca gtggccttta ttgggtcaac aggttctggt aaatcaactc
     6601 tggtcaatct gattccacgt ttctacgacg tgtcagcagg agaaattctg gtggacggtg
     6661 tcaatgttca agactatgac ttctctgcga cagctcatgc tggtcaaaag gttgccattg
     6721 ttgggccgac tgggactggt aagacaacca ttgtcaatct tttgatgaaa ttctatgaga
     6781 ttgataaggg aagtattcac attgatggtg tggataccaa ggctatgacg cgttcagaag
     6841 tgcatgatgc cttttcaatg gtcttgcagg atacctggct ctttgaagga actattcgag
     6901 acaatctcat ctataatcaa atagggatta gtgatgaacg aatgatggaa gctagtaagg
     6961 ctgtgggaat tcaccacttt attatgacct tgccagatgg ctatgatacc atcttggatg
     7021 acaccgtgac cttgtctgta ggacaaaaac aactattgac tattgctcgt gcccttctta
     7081 aggatgcacc gcttttgatt ttggatgagg cgacttcttc tgttgacaca cggacagagg
     7141 aattgatcca aaaagccatg gaccgtttga tggaaggacg cacatccttt gtcattgccc
     7201 accgcttgtc aaccatccga aatgcagact tgatcttggt catgaaagat ggaaatatca
     7261 tcgagcaagg caactatgag gaactgatgg cgcaaggtgg cttctacgct gacttgtaca
     7321 atagtcaatt tacagaagat gaagcagaag aataaatcaa aagaaggctt gacggccttc
     7381 tttttcttat ttatactagt acacatagaa agagagaagt atgagtcaga aattatacaa
     7441 tatgaaattt gctgctgtct acttagcctt gattgcaaaa gttgagcgaa agggtggaaa
     7501 ggcagagtca gttcaccaag tgaccagttg gttgacaggg tatgaagtga gtgatgttct
     7561 tgcttgtctg gatagggatg ttacttacgg agattttttt agacaagcac catattatgt
     7621 ccctgaacga attgcaatta cagggaagat ttgcggtgtc cgtattgagg aaattgatga
     7681 tcctctgatg caggaaatac gtcgcttgga caagctagtg gattggcttg ccaaggggaa
     7741 aacatctcaa caagttctag aaaagtatga gaagcataaa tgaaaaatta tcaagaatgg
     7801 tatcgaaata tcagctccag actaactagt cgtccaattc ttttattcct attacgcagt
     7861 ttcaatcgtt tgatgacagt cgccatgccc ctggtctatc tgatcttgct agtcaccact
     7921 tacctgcaac taggacttgg tcagcaagtt ggggtttatg tgcttattcc tgcatcaggt
     7981 tttgtggcct tgtccctgtt tcgtaagaaa atcaatcacc cgagacctta tgaaacttgg
     8041 gatatctgtc cccttcttga taaggatagt gcgggacggt cgatgcccag tcgccatgtc
     8101 ttttcggcaa ctatcatctc catggcctgt ctgcatgcta gtctacctat tggcttagta
     8161 tgcttgatct tttcagcttt gctggggttg gtgagggttt tagggggtgt tcattatccc
     8221 aaggatgtct tggttggcta tgcttgtggt ttggtgtggg gattcctttt cttcctattc
     8281 tgacatgtaa gttaagctag tcctacaacc acttactgct tcaaattgac cacttgcttt
     8341 tttgcccttg tattcctaac ttagctttga tatagtagag tcagaaagga gatgtgatga
     8401 agttacgaat tgagattgac ggcaatttag aggagactga aattgtcatc aagaccccca
     8461 ctttgacaga tgaaattgca gacttgcaac ggctcttgca agagtcaaag gctccgaggt
     8521 tgacttttta caaggggaca ggtgaatatt atctagacct gtcagaaatt ctcttctttg
     8581 aaacagaagg gagcaagatc tacgctcata accagaagga agcttatgag gttcgcctca
     8641 agctctatga gttggagtct atcttgcctc gctattttaa tcgagtttcc aagtcaacga
     8701 tcgcaaacat ccgtcagatt tactcagtgg acaagtcctt ttcaggaacg ggcaccattt
     8761 ccttttatca gacgcacaag gaggttcatg tctcacggca ttaccaatcc ctcctaaaag
     8821 aaaatctaag aaacatgagg taaaaaacat gaaaaagaaa gcatttggta ttgtgttact
     8881 tgtactagca gctttaatat tagtacaagg aaattttgga atcccttctc taggagggca
     8941 catttggccc ttgattggta ttgctttttt tgcctaccaa tcagttggag ctttgttgcg
     9001 tcgccactta acttcagcct cttttacagc tctagtatcc ttaatgattg ctaaccactt
     9061 ttatggcatt ttaccgattc caaaccagac actaatctgg gcaggagttc taatcgttct
     9121 cggagtaaat atgttgactc attctaacag aacttggaat gggaaaaaat ggtggtatga
     9181 tggtgaaaaa aacattctta tagataagga agttgctttt gggacaggga ctttctacaa
     9241 gcaagaccaa gaattggtag aagaccaagt agaagttggt tttggcaatg caaaaatcta
     9301 ctatgacaat gcagagatgt taggtgattt tgcaacttta aatattgaag tagcttttgg
     9361 taatgcaact gtctatgttc cgcaacactg gcgtgtcgat ttgaaagtag aaacatcctt
     9421 tggtacagcc aaggcggacg ctcctgtagc gccaacaagc aaaaccttga ttattcgtgg
     9481 agacgtggcc tttgggaagt tggagcttgt ctacgttaaa taaaaaaatc ttcacttaaa
     9541 ccatcaaaat agacgtacta agagtaggaa attgatgcct tgctctgatt tcagttctat
     9601 ggttgttaga ctttaaaaaa tgaaatgttg cctttaaaag ttgtatattt ttcgatattt
     9661 tgactcttac gtttgatgta tctatgtcct acagcgtgga tgatgtagtg taaaatgctt
     9721 taaaaaaaaa atgaatgata ttggacagtt tttttgaact tttaattgct caggagccat
     9781 gaaagcaagc gcttgggttt atgacaaggg agaatggtat tatgtaagtt cttctggttc
     9841 catgattgcg aatgattggg tcaaagacaa tggcaagtag tattatctgg cttcatcagg
     9901 taagatgctt cgcaatacct acacacctga tagttactac gttggcaact taggtgcctg
     9961 gcaataagaa taatactctt cgaaaatctc ttcaaaccac gtcagcttca tccacaacct
    10021 caaaacagtg ttttgagctg acttcgtcag ttctatctac aacctcaaag cagtgctttg
    10081 agcagcctgc ggctagcttc ctagtttggt ctttgatttt cattgagtat aagaagtcct
    10141 tttccttaaa ggaagaggct ttttacttgc ttttttgctg tttcctcatt tgtcctaaag
    10201 ccttttttgt gttaaaatga atggtatgaa agctaaaaaa atgtggatgg caggtctggc
    10261 tctgcttggt attgggagcc ttgcccttgc tacgaaaaaa gttgcagatg accataagct
    10321 catgaagact caggaagagt tgacagcgat tgtacgagac catttttcag acatggggga
    10381 aattgcgacc ctctatgttc aagtctatga aagcagtcta gagagcttgc ttggtggcgt
    10441 tatttttgag gatggccgtc attatacctt tgtctatgaa aatgaagacc tagtctatga
    10501 ggaggaagtc ttatgataca accagcaagt ttagaagaat tggcatcttt agtagaaaaa
    10561 gacggtaaga aggtcttcct ttttgtggcg gactggtgtg gcgattgccg ttatatctat
    10621 cctgccttac cagaaattga ggagagtaat ccagagttta cctttattcg agtggataga
    10681 gaccagtata tagatttggc caaactctgg gatgtatatg gaatccctag ccttgttgtt
    10741 ctagaaaagg acaaggaaat cggtcgtttt gtcaatcgcg accgtaaaag caagcaacaa
    10801 attaacgatt ttttagcagg attgaaatag gagaaaaagg aaacaatgat ttttacatat
    10861 aacaaagaac atgtcggtga tgtccttatg gtcatcgtga aaaatagcgg agatgctaaa
    10921 ctgaatgtgg aacgcaaaga caaggtagcc cgtgttttcc tcaaagaaaa tggggaaaca
    10981 gtagcttgga acatttttga ggtttcgagc ttgtttgaaa ttgcagagcg cggtcaagtc
    11041 tttttatcag atgagcaagt cgctcgtttg aaccaagaat tacaggcgga aggttttaca
    11101 gaagaaattg ttaatgataa ggaacctaag tttgttgttg gtgaaattgt cgagatggta
    11161 gctcatccag acagtgacca cctcaacatc tgccaagttg cagtcgcaag tgacaagata
    11221 gtgcaaatcg ttgcaggagc acctaatgcg cgtgttgggt tgaaaaccat tgtggctctt
    11281 cctggtgcca tgatgccaaa agggaatttc attttcccag gcgaacttcg tggtgaaaag
    11341 agttttggga tgatgtgtag tcctcgtgaa ttgcatttgc caaatgctcc gcaaaaacgt
    11401 ggggtgcttg aattatcaga agaccaagtt gtcggaacac cgttcgaccc agcgaaacac
    11461 tggactgcct aggaacttgt cagcatctga tagaaggaaa taagatggca aaaaatgtag
    11521 tgattacggg agcaacctca ggaatcggtg aagcgattgc gcgtgcttat ctggagcagg
    11581 gtgaggatgt cgttctaaca ggacgacgga tagacagatt agaaatcctc aagtcggagt
    11641 ttgcagtaag ctttccaaat caaaccgtct ggacttttcc actagatgtg acggatatgg
    11701 tcatggtgaa gactgtttgc tctgatattc tagaaacgat agggaggatt gatatcttgg
    11761 tcaacaacgc cggactggct cttgacttgg ctccctatca agactatgag gagttggata
    11821 tgttgaccat gttggatacc aatgttaaag gtctgatggc ggttactcgc tgtttcttgc
    11881 cagcaatgat aaaagtcaat caaggtcata ttatcaatat ggggtcaacc gcaggaatct
    11941 acgcctatgc tggtgccgct gtttactcag ctaccaaggc agcggttaag accttttcgg
    12001 atggactgcg aattgatacc atcgcaacgg atatcaaggt gacaaccatt cagcctggga
    12061 ttgtcgaaac agatttctca actgttcgtt ttcatggtga taaagagcgg gctgcgtccg
    12121 tttaccaagg aatagaagcc ttgcaagctc aggatattgc agacacagta gtctatgtga
    12181 ccagtcagcc tcgccgtgtt cagattacag atatgaccat tatggccaat caacaggcga
    12241 caggtttcat gattcataaa aaataagaaa tttcctcgaa aagttacaaa tttctgtaac
    12301 tttttttgat ttcctacgaa tagataagta ggaggaagaa aatatgtata ataaagttat
    12361 catgattggg cgtttaacgt ctacaccaga attgcacaaa accaacaatg acaagtcggt
    12421 agcgcgagca actatcgctg tgaaccgtcg ttacaaagac caaaacggtg aacgtgaagc
    12481 tgattttgtc aatatggtcc tatggggcag actagcagaa actttggcaa gctacgcaac
    12541 caaaggtagt ctcatttccg ttgatggaga attgcgtacc cgtcgctttg agaaaaatgg
    12601 ccaaatgaac tacgtgaccg aagtacttgt cacaggattc caactcttgg aaagtcgtgc
    12661 tcaacgtgct atgcgtgaaa ataatgcagg ccaagatttg gcagatttgg tcttggaaga
    12721 ggaagaattg ccattttaat actcttcgaa aatctcttca aaccacgtta gctttatcca
    12781 caacctcaaa gcagtgcttt gagcagcctg cggctagctt cctagtttgc tctttgattt
    12841 tcattgagta taaacattaa aaagtctgag ttggtctcag gctttttatc ttgagaaagt
    12901 cagacttttt tcttgactat ttctgaccaa gtgatacaat agaattatga attagcactc
    12961 aagttcaaag agtgctaata atatctatct cattatggag gaaatcagat gttgaaacca
    13021 ttaggggacc gtgtggtctt aaaaatagaa gaaaaagaac aaaccgttgg gggctttgtc
    13081 cttgcaggct cagcccaaga aaaaaccaaa acagctcaag ttgtggctac tggacaaggt
    13141 gttcgtacct tgaacggtga cttggttgct ccaagtgtta aaactggaga tcgtgtctta
    13201 gttgaagccc acgcaggtct tgatgtcaaa gatggcgatg aaaagtacat catcgtaggc
    13261 gaagctaaca ttttggcaat cattgaggaa tagaaggaga aagtaagtat gtcaaaagaa
    13321 attaaatttt catcagatgc ccgttcagcc atggttcgtg gtgtcgatat tcttgcagac
    13381 actgttaaag taaccttggg accaaaaggt cgcaatgtcg ttcttgaaaa gtcattcggt
    13441 tcacccttga ttaccaatga cggtgtgacc attgccaaag aaatcgaatt ggaagaccat
    13501 tttgaaaata tgggtgctaa gttagtatca gaagtagctt ctaaaaccaa tgatatcgca
    13561 ggtgacggga ctacgactgc aacagtcttg acccaagcta tcgtccgtga aggaatcaaa
    13621 aacgtcacag caggtgcaaa tccaatcggt attcgtcgtg ggattgaaac agcagttgcc
    13681 gcagcagttg aagctttgaa aaacaacgcc atccctgttg ccaataaaga agctatcgct
    13741 caagttgcag ccgtatcttc tcgttctgaa aaagttggtg agtacatctc tgaagcaatg
    13801 gaaaaagttg gcaaagacgg tgtcatcacc atcgaagagt cacgtggtat ggaaacagag
    13861 cttgaagtcg tagaaggaat gcagtttgac cgtggttacc tttcacagta catggtgact
    13921 gatagcgaaa aaatggtggc tgaccttgaa aatccgtaca ttttgattac agacaagaaa
    13981 atttccaata tccaagaaat cttgccactt ttggaaagca ttctccaaag caatcgtcca
    14041 ctcttgatta ttgcggatga tgtggatggc gaggctcttc caactcttgt tttgaacaag
    14101 attcgtggaa ccttcaacgt agtagcagtc aaggcacctg gttttggtga ccgtcgcaaa
    14161 gccatgcttg aagatatcgc catcttaaca ggcggaacag ttatcacaga agaccttggt
    14221 cttgagttga aagatgcgac aattgaagct cttggtcaag cagcgagagt gaccgtggac
    14281 aaagatagca cggttattgt agaaggtgca ggaaatcctg aagcgatttc taaccgtgtt
    14341 gcggttatca agtctcaaat cgaaactaca acttctgaat ttgaccgtga aaaattgcaa
    14401 gaacgcttgg ccaaattgtc aggtggtgta gcggttatta aggtcggagc cgcaactgaa
    14461 actgagttga aagaaatgaa actccgcatt gaagatgccc tcaacgctac tcgtgcagct
    14521 gttgaagaag gtattgttgc aggtggtgga acagctcttg ccaatgtgat tccagctgtt
    14581 gctaccttgg aattgacagg agatgaagca acaggacgta atattgttct ccgtgctttg
    14641 gaagaacccg ttcgtcaaat tgctcacaat gcaggatttg aaggatctat cgttatcgat
    14701 cgtttgaaaa atgctgagct tggtatagga ttcaacgcag caactggcga gtgggttaac
    14761 atgattgatc aaggtatcat tgatccagtt aaagtgagtc gttcagccct acaaaatgca
    14821 gcatctgtag ccagcttgat tttgacaaca gaagcagtcg tagccaataa accagaacca
    14881 gtagccccag ctccagcaat ggatccaagt atgatgggcg ggatgatgta agctttctat
    14941 agaaaacaac ttataaaaaa cacaaaagga gggaatgact aacccttctt tttataggct
    15001 ctttgtcaac tgtagtgggt tgaagtcagc taagctcgag aaaggacaaa ttttgtcctt
    15061 tcttttttga tattcagagc gatgaaaatc cgttttttga agttttcaaa gtttcgaaaa
    15121 ccaaaggcat tgcgcttgat aagtttgatg agattattgg tcgcttccag tttggcatta
    15181 gaatagtgta gttgaagggc gttgacaatc ttttctttat ctttgaggaa ggttttaaag
    15241 acagtctgaa aaataggatg agactgctta agattgtcct caataagtcc gaaaaatttc
    15301 tctggttcct tattctggaa gtgaaacagc aagagctgat agagctgata gtgatgtttc
    15361 aagtcttccg aatagctcaa aagcttgttt aaaatctctt tattggttaa atgcatacga
    15421 aaagtaggac gataaaattg cttatcactc agtttacggc tatcctgttg aatgagtttc
    15481 cagtagcgct tgatagcctt gtattcatgg gattttcgat gaaactgatt catgatttgg
    15541 acacgcacac gactcatagc acggctaaga tgttgtacaa tgtgaaagcg aagctgttta
    15601 gccaagccat agtaagggct aaacatatcc atagtaataa ttttgacgcg acatcggacg
    15661 gctctatcat atttaagaaa gtgatctcgg atgacagctt gtgttcttcc ctcaagaaca
    15721 gtgatgatat tgagattgtt aaaatcttgc gcaatgaagc tcatctttcc ctttgtaaaa
    15781 gcatactcat cccaagacat aatctcagga agacaagaaa aatcatgt
//
LOCUS       DAVLDI010000051        15311 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLDI010000051 DAVLDI010000000
VERSION     DAVLDI010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15311
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.051"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(264..1871)
                     /locus_tag="VXD01_001735"
     CDS             complement(264..1871)
                     /locus_tag="VXD01_001735"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV0602087.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2249..2836)
                     /locus_tag="VXD01_001736"
     CDS             complement(2249..2836)
                     /locus_tag="VXD01_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV0602088.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(2964..3413)
                     /locus_tag="VXD01_001737"
     CDS             complement(2964..3413)
                     /locus_tag="VXD01_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEV0602089.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            complement(3418..3807)
                     /locus_tag="VXD01_001738"
     CDS             complement(3418..3807)
                     /locus_tag="VXD01_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV0602090.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQTLLADRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3835..4461)
                     /locus_tag="VXD01_001739"
     CDS             complement(3835..4461)
                     /locus_tag="VXD01_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV0602091.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4475..5038)
                     /locus_tag="VXD01_001740"
     CDS             complement(4475..5038)
                     /locus_tag="VXD01_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0602092.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5203..5437)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5491..5994)
                     /locus_tag="VXD01_001741"
     CDS             complement(5491..5994)
                     /locus_tag="VXD01_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV0602093.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6187..7017)
                     /locus_tag="VXD01_001742"
     CDS             complement(6187..7017)
                     /locus_tag="VXD01_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV0602094.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7002..8684)
                     /locus_tag="VXD01_001743"
     CDS             complement(7002..8684)
                     /locus_tag="VXD01_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602095.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(8795..9043)
                     /locus_tag="VXD01_001744"
     CDS             complement(8795..9043)
                     /locus_tag="VXD01_001744"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602096.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVR"
     gene            complement(9050..9598)
                     /locus_tag="VXD01_001745"
     CDS             complement(9050..9598)
                     /locus_tag="VXD01_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV0602097.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(9613..10461)
                     /locus_tag="VXD01_001746"
     CDS             complement(9613..10461)
                     /locus_tag="VXD01_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV0602098.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10650..11999
                     /gene="trkA"
                     /locus_tag="VXD01_001747"
     CDS             10650..11999
                     /gene="trkA"
                     /locus_tag="VXD01_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV0602099.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            12003..13442
                     /locus_tag="VXD01_001748"
     CDS             12003..13442
                     /locus_tag="VXD01_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV0602100.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(13568..14026)
                     /locus_tag="VXD01_001749"
     CDS             complement(13568..14026)
                     /locus_tag="VXD01_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS alpha-glucoside transporter subunit IIB"
                     /protein_id="HEV0602101.1"
                     /translation="MEVVLFSYCLNTRYLLQIVDIASSNDIILEEDTSEIMPGEIDVI
                     KSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIILA
                     PQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            14587..14757
                     /locus_tag="VXD01_001750"
     CDS             14587..14757
                     /locus_tag="VXD01_001750"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0602102.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEKAG"
BASE COUNT         4602 a         3434 c         2761 g         4514 t
ORIGIN      
        1 agatgttcac atcttatttc aattcactat acaatccagt tcctaaaact ttgctagaaa
       61 ttgatttggc tttccgaatt aatttgttca aattttattt catttcaata tactgataaa
      121 tccattcact agcacagggc aagagggagt cgctattgat ttcaacggta gcaggtacat
      181 acagaggact cctacctcag atatactgca atatcatcgt atgcaaaaaa cctctgagat
      241 ttttctcaaa ggttctgatt ttgctaattg ctgttctcaa ccgctgcagt aacaaaggca
      301 gtgtagagtt cttctggtcg gtttggacgg cttgacagtt caggatgata ctgacaagct
      361 acaaagaatt tattttcagg aatttccacg atttctacca aacgattgtc tggagaaact
      421 cctgaaaaga caaaacctgc tgcctcaaac tgctcacgga aggcattatt aaactcataa
      481 cggtgacggt gacggcgttg caccacttct tgattgtgat aagcagcagc agccttagag
      541 ccacgtttca acttagacgg ataaagtccc aaacgaaggg ttccacccat atcctcaata
      601 tcaatctgat cacgcatgat atcaatgata gggtattttg tttctggtgc aagctctgca
      661 gaattggcac cttcaagacc taaaacgtga cgagcaaact cgatacatgt caactgcatt
      721 cccaagcaga ctcccaacat tggaacatca ttttcacgcg catagcggat ggcttggatt
      781 ttcccttctg taccacgttg accaaaacca cctggtacga tgatcccgtc cgcatcagac
      841 aagagttctg ctacattctc tgctgtcaca tcattggcat tgacccaatt gattttaact
      901 tctacatcat tgacatagcc agagtgtttc aaggcttcga ccactgagat ataggcatct
      961 tgcaactcca catacttacc aacaagggaa atcttaactt gtttcttgag gttcatgacc
     1021 ttgtccacca tggctgacca ttctgtcata tccgctgctg gtgcgtctaa tttcaaatga
     1081 tcacaaacaa tttggtccat cccttgtgcc tgcaagttca gtggaatttg gtaaaggtgt
     1141 tcaacatcca acgattcgat aacggcttct ggtgccacat cacagaactg ggccagttta
     1201 tttttaattc cttgaccagc tggctcttct gtacgaataa ccaacatatt tggttggatt
     1261 cccaagccac gcaattcttt gacagagtgt tgggttggtt tggttttcat ttcaccagca
     1321 gccttgaggt aaggaagcaa ggttgtatgg atatacatga cattatccgc acccacatct
     1381 gccttcatct gacgaagagc ctctaggaat ggcaaggact cgatatctcc tactgttcca
     1441 ccaacctctg tgataatgac atcagagtcg gtcgttagag cggcacgctt gattttttct
     1501 ttcaaagcat ctgtgatatg aggaatgact tgaacagttg ccccaaggta ttctccacgg
     1561 cgttctttac gaagaacttc actgtaaatt ttcccagttg tcacgttgga atatttgttg
     1621 agattgatat cgatgaaacg ttcatagtga cccaagtcca aatctgtctc agctccgtca
     1681 tctgtcacaa aaacttcccc gtgctggtaa ggactcatgg ttcccggatc aatattgata
     1741 taagggtcaa acttttgaat ggttactttg agaccacgat ttttcaagag acggcctaga
     1801 ctcgctgcca caatcccttt cccaatagac gataccacac caccagttac aaaaatatat
     1861 ttcgtagaca tagattcctc tttctaaaat gctcaaggtc ttgttaacta cgaggggata
     1921 tagaaaacaa gaccctacta ataagaataa tctgggacga ctgcaccaga ttcacagcta
     1981 atactcttca aaccgcgtca acgtcgcctt gccgtagata tgtgttcctg actttgtcag
     2041 tcttatctac aacctcaaaa tagtgttttg agcagcctac ggctagtttc ctagcttgct
     2101 ctttgatttt cattgagtat aaaatacaag aagataactt cttgaaaaaa caaaaatagc
     2161 tccctaagaa ctagggagcc ccgacctcta aaagaggtgc ccaaacaata tgatacctaa
     2221 aaataggata attgtcaata gctaactctt attcctcgct ggtttcagcg tcgtcatctg
     2281 aaaactcgtc gtcgtcttcg ttgagatcca catcttctcc caagtcatct ggagcgattt
     2341 cgttgatttc tgcatcataa gcttccactt catttttttc atcatctgga ttttcatcat
     2401 cgtatgaaag agctggatct gcttcgtatg catcttcgtc ttctggatca tctgcattgt
     2461 agtcaatggc atctgaatca ccatccataa aggcattgac acgttttttc ttagcttttg
     2521 gtgctacttc atcgtcgtca ttttcttcaa gagcgatgat ttcttcgtcg atttcgtcca
     2581 caccatacca tgaacgaaga ccccatttgt tgtccccaag tgagatgaag ctaccgtcaa
     2641 agttcaactc tgtgtagaac aaaggcaaag cttcgcggat atcgctgttt gatgttccaa
     2701 ggtagttttg aatttcgttt acaagatcgc taaaatgcat ctcatgatcg cgaccacgaa
     2761 gttccaagat agcacgcgct acctcaatca tagatagttc acttttttct tgcccagcaa
     2821 atacttctaa ttccaaagcg tttctcctca tttatactac tatcgccaga gcgaacagac
     2881 tctgacctca ttttatcatt tactctttat tttacgataa ttttgcagaa tagtcaaagg
     2941 ttaaggggga gaaaatggca ggattagact aattccaata taaaactcat tcctttttct
     3001 gttgctccat tttccacaaa tccaagcgac ttgaaacacc tcctagaagc atgattgtag
     3061 gtgtagattt ccttgactct caattctttc catcctttta ctcgagccaa ttcaatcaaa
     3121 gcacttagaa tcttttttcc aagtcctcga tgttggtaag cggaattccc aatcacaatg
     3181 gggagattat cctgagatag tgtaatatcc ccaattggaa accattctcc cttctccttg
     3241 acttcaatcc aaaaaagctc accatgccga tccaaatagg aatacatggc ttccaaggtc
     3301 gcttgactgt aaggaagctt caccccatct acgaggtaaa ccaagttcac atcctgatac
     3361 caagcaaaag cttcctcaca atgattgacc ttataataag gaacaaaaca caatgcacta
     3421 ccttttcaac aaaagagttg ctgcttgatt aaaaccatca caccagttat accattttgc
     3481 ttcataccca tcttgagcta ggatacgatc ttctaaatca aaaacagagt aaatctttct
     3541 ttcctcgcaa gcttgcgcat agagatgata tagttcatca ccaccatctc tatcccactc
     3601 agcagaaatc gtatcccgat ctgccaataa agtctgataa gccctgtgat gcccatctgt
     3661 aatcagcaaa caatctccaa aggcaagaat actgattgga tcgacttgga ttgtttctgc
     3721 cgactggtaa agcatctgaa tatcttgcaa cttcttttct gataaatata gttgagtcgg
     3781 atgaagatct gctatgttga ctttcatttc tttctcctca agggaattcg atactcactt
     3841 ctgtttgcct ttaaatcgcc attggaagcg gagcttgtca tagaagggaa actcgataaa
     3901 caggactccc aagcccacac agagactggc aaggacgtct gatgggtaat gaactcccag
     3961 atagactctt gataccagca cactgactag gtagaggcca aggacgattt gtacgatttt
     4021 tctccagact ggatctttaa tccgctgact aagaataaca atcaaagtac ctaccatcaa
     4081 ggttacagcc agagaatgcc cacttgggaa ggaaaatccc ttctcctcca ccagatgtaa
     4141 gatatctggc cgtgggcgct ggtagatatt tttaaaggtc acgattaaaa gacctgccaa
     4201 agccagattt cccagcatga agaaactttc tatcttccat cgcttacgat aaaagacaaa
     4261 agctgtaatg acaacccaag tgataatcac tgggatatca atcagacgtg tgagggctcg
     4321 aaaaagaata gtcaaataat ctggtaagtc tcctcgaatg gcagtctgaa tcgattggtc
     4381 aaaattgacc agcgtttcag ggtaaaattt gaccatgtag ccaagaataa cgaaaagtaa
     4441 aagggcaaaa ctgcccttca ttaaaaatgt ttgtttatct ctcataatgt tttaaggttg
     4501 gtttcaagag aacatacaac aaccagaatg aaacggaaaa gataacacct tcaatcaagt
     4561 taaaaggtaa taccatggtc attaggtagt tggaaagtcc caaaattttt ccaatatcaa
     4621 agttagcaaa cttagcgtac aaaggaacag cataaacata gttgagaacc aacatggcca
     4681 aggttaaacc aatagttcca gctagagagc ctagtaggaa acgaagggtt gtccgttcct
     4741 ttttccaaat caaagcaaat acgatgacaa aaactcccaa agctacgata ttcatcggca
     4801 aaccaatgta agtattcact ccttggctgt taagaagcaa cttcaagagt gagcgaagca
     4861 agagcactcc tagagcagca ggcaaatcca tgaccaccag acccacaagg actggcaaga
     4921 tactaaattc gatcttgagg aaagatgccg ctggtaaaag cggaaaatca aagtacatca
     4981 gcacaaatga gatggctgat agaattgcaa tggtcgaaag tcgacgtgtg tttgtcataa
     5041 caggttcctc caattttcta taaaatcaga agaagttgga aaggattcct ctatctattc
     5101 tcacttttta tatcccaaaa gttccctctt actctattaa agaaaaacaa agcaagtggt
     5161 tacaatccgg ctataaatct atcaaaacag acaaagctat tctttcgtct tctcccatcc
     5221 agactatact gtcggttgtg gaatctcacc acatcagctt gcgctcgcgg acttctttaa
     5281 agagaaagaa atagagattt ttcttttaga ctaggcgaca agctgtaggc ataacttctg
     5341 gttaggcaaa gcttgtcaac aaagtataaa aggaaaagat catttcctag ttaaagtcac
     5401 cgccggtcgg gaatcacacc ctgccctgaa gactctttta tcataacaaa aaacgcttgc
     5461 aagcgcaagc attttgttca ttttcatttt ttatttcaat ttatccactt cataggtatg
     5521 gacgagctca agacctgcaa agttctgctg gcgaagagcc tcatagacaa tcatgcagac
     5581 ggtattagac acattgagac tgcggacatg ttcatcattc atgggaatac ggagagcctt
     5641 ctcaggatgt tctcgcataa aatcttcagg taagcccttg tcttcacgtc caaagagaaa
     5701 ataatggtcc tcgtcagtcg ataaatccac ctcagaatag attttttccg cgaatttcga
     5761 aatcagatag agttttccct tcatctgaga tatgaaatct tctaaactct cgtaaaaata
     5821 aatctctagc ttatcccagt aatccaatcc agcccgcttc atcttgcggt catcaatagg
     5881 aaagcccata ggcttgatga tgtggagggg agaattggtc gcagcgcaag tacgcgcgat
     5941 attgcctgta ttttgtggaa tttgaggttc aaataataca atgtgatttg tcatgacttg
     6001 cttcctttca ccattgcaaa aaaatagcca cactgcccgg agtcaagctc agcaaacagc
     6061 gtggttaagg catcgttaac ttacctcaca acaggtttga agtaaatcag cgaaactact
     6121 ttcttagtat aacactttca gaatcattgt caatagaaat gacttgattt tttcaatttt
     6181 ttcaagctat ttccaagggt tgtaaaatcg tccctgattc tgcaagataa gtagtaaact
     6241 aactactaaa aacaaggttg ccaagagcaa ggtaatatag tctccttttt tcaaggcctg
     6301 ataactatac catgtgcgtt ttttctcttt cccaaagcgg cgaagctcca tggcagtcgc
     6361 aatggtatca atgcgttcta gcgagctaaa aatcaagggc gtaataatga gcagattgcc
     6421 tttgattcgt tgcataagag aagctttctt ggataattcc atcccacgcg cctcctgaga
     6481 catcttgata gtaaagaatt cttcctgcaa atctggaata tagcgcaagg tcaggctgac
     6541 agaataagca atcttatagg gcacaccaat ttgatttaaa ctggaagcaa actgactagg
     6601 atgggttgtc atcaaaaaga taatagccag aggaatggtg caaagatact taatggccaa
     6661 atttagcaga taaaagagct cctggctggt tagagtgtag acaccgattc cctgccaaat
     6721 cacacttctc tctccataaa gtccaacccc atactcggga gaaaagagat agaccatcaa
     6781 aacgtttaaa acggcaaata ccgtcgcaaa aacggctaca aaggaaacat ctttaaagcg
     6841 aatttctgat aaatagagga gaaagactga aaagatggca atcagcaaga gcattctggt
     6901 atcatagcta atcatggccg ccaatgatac cagaatgaaa aagagaagtt tcccagctcc
     6961 tgacaagcga tgaatcacag tatctctatg ctggtaaccg attaatttag cttgcatccc
     7021 tctctccttt ctttgtaaaa tgccgttaaa tccagtggat ccacatctag tttcttagcc
     7081 aagttaaaga tggaggtttc ttttagattg gcttttacta acagctcagg atcgctcaac
     7141 agactggctg gaacagtatc ggcaatcaat tctccatcca ccatgacaag gacccggtct
     7201 gaataatcca gcatcaattg catatcatgg gtaatcatga caatggtatg ccctttttga
     7261 tgtaactctt cgagaaattc cataatctca gtatagttct tctgatcttg acctgcagtc
     7321 ggttcatcta ggagaataat ttcagctcct aagaccaaaa ttgaagcaat ggtgacacgt
     7381 tttttctgac caaatgacag ggcagaaata ggccaattac ggaattcata aagtccacag
     7441 attttcaagg tttcatagac tctcgtttca atttccttct catccacacc tcgcaaacgg
     7501 agccctagag ccacctcatc aaaaatcata ttggttgaaa tcatttgatt aggattttgt
     7561 agcacatagc ctactcgttc cgcccgctct gcaacagaat cgccttttat atcctgtttt
     7621 tcccaaagat agcgtccttc cgtctgaata aagctactta tagccttggc tagagttgat
     7681 ttccctgctc cattttttcc gacaatagca atcttttcac cctttttaat atctaaatgt
     7741 agggatttta aaatcggtct atcatcataa gagaaagaca cgtcctctaa tttaaagagt
     7801 gactgcaatt ctggagtttc ttttgccagt tcattctgca gctgaacctg accttttgag
     7861 atagacatgt tatccagatt cgctaactgt tcttccttga ctaagtccac acctaattga
     7921 cggagagtcg ttagataaag gggttctcga attccatttt gagtcaataa atcagtcgca
     7981 agcaactggt cagggctccc attaaaaagg atacgaccat cgtttatcaa gacaatccga
     8041 tccacagggc gatgcagaac atcctccaaa cggtgctcga taatcagagt cgtcgtcccc
     8101 tcttccttat gaatctggtc aatcaattcg ataatatcct gacctgactt gggatctaga
     8161 ttggcgagtg gctcatcaaa caagagaatc ggactttcat caatcaagac accagccaga
     8221 ctgactcgct gcttttgtcc acctgacaaa tcctgaggac gctgatccag taaaggaaga
     8281 aggtccagct tttcagccca tttataaaca cgacctttca tctcatctag ggctgtcaca
     8341 tcattttcca gagcaaacgc caaatcttct gccacagaca agccaataaa ctgcccatct
     8401 gtatcctgca aaactgtgct aaccagatga gacttatcat agatgctcat atcaaaggct
     8461 acttgaccct ttatcaaaaa ttctccatat gtctgaccct tgtaaatatt gggaataatc
     8521 ccattcaaac actgacccaa ggtagattta cctgacccag atggtccaac aattaagact
     8581 ttctctccct tgtaaatggt caagtctatc ccttgcaagg tcggttcttg ttgtgtttca
     8641 taccggaaag agaaatcctt ccactcaatt atagcttctt tcatcttact ctcttcattc
     8701 gcttcttaga cttctatttt atcataaatc aagcccttct tgcagtctct cctcttaaaa
     8761 tcttagcgcc aaaaagattc ctatcctagc ttacttacct aactaatcta taaacatcga
     8821 aaaagactag ttgcccagcc ttccccatca ttttatactc ttcgaaaatc tcttcaaacc
     8881 acgtcagctt cgccttgccg taggtatggt tactgacttc gtcagtttca tctacaacct
     8941 caaaaccatg ttttgagctg acttcgtcag ttctatccac aatctcaaaa cactgttttg
     9001 agcaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat tagtcctttt
     9061 tcaaacttcc tgcacgagtt tgggttcctg cataggcaag taagagaaga gttcctgcaa
     9121 tagctacaga tacaccattg gcaattcccg caacaatccc ttgtgcaaat actttttctg
     9181 ccgcttcttg ataaatcaca acatctccaa gtggtgccaa gacaccccaa acaagggcat
     9241 ttgcaagtag ttgaatgagg ttaaaaataa gaatatcttt ccagtcaaaa acaccattga
     9301 tcactcgaac gtactttcta aaaagtccca caactagacc aaagagtccg ctagcgataa
     9361 tccaagtcca ccatagacca taaccagcaa gagagtcctt gattgcatga ccaatcaacc
     9421 cgacaagcaa accgataatc ggtccaaaaa taatagaaag tagcgcttgt accgcatact
     9481 gaagctggat gcttgtattt ggaacagggg ttggaatgtt gatcatcccg atgacgacaa
     9541 agagggcagc gccaattccg acagcaacaa cttgtttaat tgtaaatttg atttccatac
     9601 tattctccta ttttatcctt ctattttctt tatttcaatg gtccaagatg aaccgacacc
     9661 tacattatag gccttggcaa aggaaccttg gttgatagcc aaacctaaac gatagagaga
     9721 gttgatgtaa aggatgggtt gcccaattct cacatctgca aatgatttgc catagacaac
     9781 ctgattttga tagaccagca tatcagcatg atagatggtc acttcaaaac gatcaccaaa
     9841 ttctggttcc agcttgtaaa attcttcccg tgtgatagag gtccaaagcg aaccgaaacg
     9901 cacatccaga atatcaatgg ctcccttcac cagatgatct tctatgatgg tcgctacgac
     9961 tggaagctct acaatctgtt ccacactgag ctctggccct acttcctcaa aagtaatgtg
    10021 accactggcc agtttagcac cagtataggc atagacatca cgaccgtgga aggtataaga
    10081 atgctctgtg ttttgacgcc tattggccac ctcagaaatc tcacgaatgg ctacaatgcc
    10141 aacgtgtttc ttgataaagg aaagcgtccc attatctggc gtgacaatgt attgattttt
    10201 tgcagtcttg gcaactacac tcttacgttt cgaaccgaca cctggatcga caaccgatac
    10261 aaacgtcgtt ccctcaggcc agtaatccac cgtctgaaag agacgatagc tcccctcaaa
    10321 aatattataa ggcgtgatat cgtgcgtcaa gtgatggatt tttaaggttg gagactcttc
    10381 taaagccact ccaatcatag ccgataccgc accatcaacc agaccaaagt ctgattgtaa
    10441 taccagtaaa ttattattca ttttatctcc ttgtatatcc tttatcatac catatttcag
    10501 agaaagtcgc taatagctat ttcaattggt tagggtatag ttttacctta tagcaaattt
    10561 cctactaaaa gttcttgtta ttagctagta ggtgcatttt ttcttgaaaa agggtatgat
    10621 agttacatca tgaaaaagta ggttttatta tgaaaattat ccttgtcgga gggggaaaag
    10681 ttggttttgc cctctgtcgc tccttggttg cagaaaagca tgatgttttg ctgattgagc
    10741 aagacgaagc tgttctcaat catattgtca gtcgctttga tatcattggt atccttggta
    10801 atggggccga ttttgccatt cttgagcaag ccagcgtcca agattgtgat atctttatcg
    10861 ccctgactga gcacgatgaa gtcaacatga ttgcagcagt tctagccaag aaaatgggag
    10921 ctaaagaaac tatcgttcgg gtgcggaacc ctgaatattc taactcttat ttcaaggaaa
    10981 agaatattct cggtttttct cttatcgtta atcctgagct cttggctgcc cgcgctatcg
    11041 cgaatatcat tgacttcccc aacgccctgt ctgtcgaacg ctttgctggt ggacgcgtta
    11101 gcctcatgga atttgtcgtc aagtccacca gcggtctttg ccaaatgccc atttctgatt
    11161 ttcgtaaaaa atttggtaat gtcattgtct gtgcgataga gagggatcat caaattatca
    11221 ttccaagcgg tgacatgact gtacaggata aagatagaat ctttgtcact ggtaaccgtg
    11281 tcgatatgat actcttccat aattatttta aatcacgcgc cgtgaagagc cttctcatcg
    11341 ttggggcagg tagaattgcc tattatctac ttggtattct caaagatagt cgtatcgata
    11401 caaaagtcat tgaaatcaat cctgaaatcg ccagcttctt tagcgagaaa ttcccaaatc
    11461 tctacatcgt tcaaggagat ggaaccgcaa aagatatcct gctggaagaa agtgctcaac
    11521 actatgatgc cgttgcgact ctaacaggtg tcgatgagga aaatctgatt acatctatgt
    11581 tccttgacag ggtaggtgta cagaaaaata ttactaaggt caatcgtacc agtctcctcg
    11641 agattatcaa tgcgcctgat ttttcaagta tcatcacacc taaaagcatc gctgtagata
    11701 cgattatgca ctttattcgt ggtcgagtta atgcccagta ttcagacctt caagccatgc
    11761 accatctagc caatggccaa attgaaaccc tgcaattcca tatcaaggaa gccaataaaa
    11821 tgactgccaa acctctttct caactgaaat tgaaaaaagg ggttcttatt gcagccatta
    11881 ttcgaaaggg caagactatt ttcccaactg gggaggatat gttggaagtt ggagacaagc
    11941 tcctagtaac aaccttgttg ccaaacatca ccaagattta tgacttgatt gcgaggtaag
    12001 aaatgaataa aagtatgatt cgttacctcc tttcaaagtt acttttgatt gaagctgttc
    12061 tcctcttggt tcctgtggct atcgctgtct attaccgtga atcgagccaa gtctttacag
    12121 ccctcttttc gaccataggg attctcgtat tgttaggcgg ttcagggagt ttacagaagc
    12181 caaaaaatca acggatttat gccaaggagg gagtcttgat cgttgccctc tgttggatcc
    12241 tttggtcttt ctttggtggt ctcccctttg tcttttctgg gcaaatccct agcgttattg
    12301 atgccttttt tgaaattagt tctgggttta caactactgg agcaagtatt ttgaacgaca
    12361 tttcggttct cagccgttcc ctcctcttct ggcgaagttt tacccacttg attggaggga
    12421 tgggagtgct tgtttttgca cttgctatta tggacaatgc caaaaatagc cacctagagg
    12481 tgatgaaggc tgaggttcca ggtcctgttt ttggcaaggt tgtatccaaa ctaaaaaaca
    12541 ctgcccagat tctctatctc ctttatctag ctctcttctc cctctttgtc atcatctatt
    12601 atctagctgg tatgcctctc tacgatagtt ttgtcattgc tatggggaca gcgggaactg
    12661 gaggctttac cgtctataac gacggaattg cccactatgg cagctcactg attacctatc
    12721 tggtcagtat cggagttctg gtttttgggg taaatttcaa cctctactac tacctcatgc
    12781 tccgtcgcat caaggccttc tttggtgacg aagaacttcg ggcttacttg gtcattgtac
    12841 tggtttctac aggcttgatt agcctcaaca ccctctacct ctacccaggg ttttcaaaga
    12901 gctttgaaat gaccttcttc caggtttcca acatcattac aacaactggt tttggatatg
    12961 gagatattac caactggccc ctcttctccc agtttatcct ccttttcctc atggcaatcg
    13021 gtggctctgc tggatcaact gcaggtggac tcaagattat tcgaggcctc atcctttcaa
    13081 aaattgccaa aaaccaaatt ttgtcaatcc tatcgcccca ccgtgttttg accctccatg
    13141 tgaatcaaac ggtgattgat aaagataccc agcataagat tctcaagtac tttgtcatct
    13201 atgctatgat tttgctagcg cttatcttta ttgtcagcct agatagcaat gattttctgg
    13261 tcgtgaccag cgctgtcttt agctgtttca ataatatcgg gcctattcta ggaaccactt
    13321 ctagtttctc aatctttagt cccatctcaa aaattctcct atcctttgca atgattgcag
    13381 ggcgcttgga gatttaccca atcctccttc tctttatgaa gagaacttgg tctaagagat
    13441 aaaatacaaa atccctcttt ttacaattgt gaaagaggga ttcttatatt aaaaaagggg
    13501 gaacgttttt aaatccaagc ctatctgtaa gcaaaatcct tactcaaata aaagatggaa
    13561 aaacttacta cacagcttgg taatgctcca atacaaattg taaggattta cttggactct
    13621 ttgttaaatg aatatattcc attcctctgg tagcaactat ctgaatacct aatctttctg
    13681 catccacctt catctctcta taataactcc gaacttgtgg agccagaata attaaatcat
    13741 aaacacccat aatatcataa tgagctccgt acgctcctga attcgcaatc actctaactt
    13801 ctgctaattg agcgccctcg ttaattgcat tggctaattg cgcacttgtt ccagaccctg
    13861 cacaaagaac cagtactttc aactccttac tttttattac atctatctca ccaggcatta
    13921 tttcacttgt atcctcctct aaaataatat catttgagct tgcaatatct acaatctgta
    13981 gtaaatatct cgtatttaga caatatgaaa acaagacgac ttccatatag gaaaccgcct
    14041 tctcgctatg ttgagtgatt tatattaaaa taacttttct tctagctgca ttttattatt
    14101 ataaaaacat tcatcataac ccccagaact taaataacaa tttttattca agatacatac
    14161 tcctagaata aactttatat gaaattctca tttttgtttt tacaattctc cttagttaaa
    14221 tcttgtttaa tatatgtttt acatatagta tttagcgcca catagtactg aactctctcc
    14281 aaaaacggtt atgcctcttt gaatagggcg ttatcacaag aaaagcatct ccacgtttca
    14341 acttcatatg gctcaaaaac aatcaattga tgctaaaacc tgtacctaga tgtttcggtt
    14401 cataaaacca tgaaactgta aaagtggatg aaattgatag cgatagtcaa atcaagaggc
    14461 atcataactc taaaaagtca caatatataa gttcatcctc ggaaaaatat cattctaatt
    14521 gttgaaatgc ctacatgaaa agaaacgtca aatactcatg aaacaacgaa tacaggtatc
    14581 aaaactatga caaaacaagt ccctaaattt actaaagaca ctgctcaact ttacacctgt
    14641 aaatggttgt tgtataataa agttacaaag atgtacgacc acactgttgt aaatcatagt
    14701 gttcgcgaat atattactga tagcatttct acaaatacaa ttgaaaaggc tggataggct
    14761 ttaaacgaaa tatgtcagtg ttttggcatt cctagccttc atatcattta aagaattgta
    14821 tagacaaaat ttttcccaat acagacactc gtaacaactg cttcattttt ctaccaacat
    14881 atttaggaac aggataagat acaagaggat taatccatag atcagttcta taccaatcta
    14941 agacaaataa gctaaaaaaa cgattgataa taagcaaata gattccaaat tttctctatc
    15001 tgctcatttt aataaacaat actagtgtaa ctatccttcc agtcagaagc ttgtcaaatc
    15061 acaccgaaaa ttcttctaaa atttatctcg ttaggcaatc aagcaaaaac tcgacgatag
    15121 tacaaacatt atcatacaga attgacttcc taaattatat actttagtaa ggttttcgga
    15181 taagaaaaaa ggttcatttt acatttctaa acattctttt ctaagatgaa aaacagaatt
    15241 tttcgattgt gatttaaagc aacaagaaga ttttcagtat catcctatag atacgagcta
    15301 attaagaaaa a
//
LOCUS       DAVLDI010000052        14462 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLDI010000052 DAVLDI010000000
VERSION     DAVLDI010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14462
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.052"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(7..303)
                     /locus_tag="VXD01_001751"
     CDS             complement(7..303)
                     /locus_tag="VXD01_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602103.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(287..2446)
                     /gene="pfbA"
                     /locus_tag="VXD01_001752"
     CDS             complement(287..2446)
                     /gene="pfbA"
                     /locus_tag="VXD01_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV0602104.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNN
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3577..4803)
                     /locus_tag="VXD01_001753"
     CDS             complement(3577..4803)
                     /locus_tag="VXD01_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV0602105.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWRANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4846..5538)
                     /locus_tag="VXD01_001754"
     CDS             complement(4846..5538)
                     /locus_tag="VXD01_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV0602106.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMHYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5711..7462)
                     /locus_tag="VXD01_001755"
     CDS             complement(5711..7462)
                     /locus_tag="VXD01_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602107.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQETSDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGLSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMADTL"
     gene            complement(7452..9197)
                     /locus_tag="VXD01_001756"
     CDS             complement(7452..9197)
                     /locus_tag="VXD01_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0602108.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     CLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9403..9699)
                     /locus_tag="VXD01_001757"
     CDS             complement(9403..9699)
                     /locus_tag="VXD01_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV0602109.1"
                     /translation="MSASDVALKLRGQGIFQMKQVKRAVQEQNGQLIVVQMGDENSKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9852..10307)
                     /locus_tag="VXD01_001758"
                     /pseudo
     CDS             complement(9852..10307)
                     /locus_tag="VXD01_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10440..11267
                     /gene="xth"
                     /locus_tag="VXD01_001759"
     CDS             10440..11267
                     /gene="xth"
                     /locus_tag="VXD01_001759"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV0602110.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11279..11422
                     /locus_tag="VXD01_001760"
     CDS             11279..11422
                     /locus_tag="VXD01_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0602111.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCDLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11422..11661
                     /locus_tag="VXD01_001761"
     CDS             11422..11661
                     /locus_tag="VXD01_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV0602112.1"
                     /translation="MLEEGTKDQLAELTYLFGRGVNLSFGIKDVSKLYQRVMKANYPI
                     YRPLTKRKFRVSDHYIYPHEFAVLDPDSYFLRFSE"
     regulatory      12045..12140
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12540..13121
                     /locus_tag="VXD01_001762"
     CDS             12540..13121
                     /locus_tag="VXD01_001762"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV0602113.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13121..14383
                     /locus_tag="VXD01_001763"
     CDS             13121..14383
                     /locus_tag="VXD01_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV0602114.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIAMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
BASE COUNT         4273 a         3081 c         2712 g         4396 t
ORIGIN      
        1 ctattattat ttcattttac tatactctgt taattcatat gagtttaaac cgatttcatc
       61 tttaacctcg agtaaagcag tttcaaatat ttgtttaaga gtttttgatt ctttacaatt
      121 aaccgacaaa ctttctgata aaatatgtac aacttctgag actgaataac ctatctcctc
      181 tttagaatta tataaatctg tagctccacc aataatccaa aaatactgat tttgtgaacc
      241 tacaatatcc tcattttcta cggaacttcc ttgtatcgaa caaattttat ttatctttac
      301 cataatactt caaccctttt agtgtcaaaa gtaaaccaat tcctgtcact gttaagaata
      361 gttccataat cttgttcgaa ccagtctttg gtaatttttg ttttacatct actatttctt
      421 tagatttatt aatatgattt tcagtttctc tgccatctcc aactatttta tagtttactt
      481 cttctgtctt attatcttgt ttattgtcga tcttgtcatt catttgtcta ttatctttac
      541 ttgagttaaa ctctccgttc ttctggttac tatcaattac attatttgaa ttagattgtt
      601 tttcctcttt gtttttttct ttttcgtttt tatcacttaa attatttgtt acaattttgt
      661 aaagcccatt ctccgttaca atattgaaat taccatcgct atcacgtata acaggttctt
      721 tcccatttgc attagatttg atgaatgata tatacttacc ggataaatta taaaattggt
      781 tatttaaaac ggttatttta ccctttgaat cctcaataac aattccttct ttaccaccga
      841 atatactatt ctctgagact actaaattat cactaactcg taataattca atatttggtt
      901 gttctgtttc cttagaatta ttattaatta cattttttgt tacagtaata tctgatactt
      961 ttcctaaata ttctgcacta tcttttgcaa ctcgtatcgc ttttgtttta ggatcggcaa
     1021 tattaaatat attttcggcg ataaccacct gtttatttaa atctaatagg tctttagtgt
     1081 ttttatagct ataagcattt actaaagctg ctccgttttc tcgataatgt acactctctc
     1141 ctttaacttt cttatcaaag cgatttcctt tgattaatac atcagtgaat cctgtaaaac
     1201 gtacacctgc atacatcatg ttatcaaaat gattatttaa aattttaata ttagaggggt
     1261 tctgtgttga caatgtttga tagtgtgtgc caattgctgt tactaattcc ccagatttat
     1321 cacttttgcc aaaataggaa ttttgaatag tcacattttc agattttttc ccatcatcat
     1381 tcaaggcata aggaaaacct tttctagtta atggttcaat ctgaatgctc tccttactta
     1441 tgatttgccc atccttcatc gttttgggta aggcttgccc aagaaaacga gaattatcaa
     1501 ctaatacatt tttcgaacct gcaatttgaa tagcatgccc ttgataacta tccttgaatg
     1561 ttacattttt tatagttacg ttatttgaat tcccaatagc aaatgcacct gaagaattta
     1621 taagtggtag attttttgct ttagttcctt cttcattcaa agcaccgttc atatcaatcg
     1681 taccaccaga ataactaata tcttctgttg ggccccattc tacttgcgca ccatcatccg
     1741 taaataaacc tgtcataaaa acaatggaag ggtgattctt aatatttata ccatttagaa
     1801 ttgtagcttt ctcattcaat tctaagtgtg tatgactttt taaaaaaaca atttctttta
     1861 ctaaataagt tccttcagga aaatatacat ttcctccacc tagcccttga gctgcagcat
     1921 ctattgcatc ttgaattgct tgtcgatcat catgaatccc atcacctact gcaccataat
     1981 cttttacact taaagcagta tcttcaaatt cttttttgat aattctgtca cttataacat
     2041 cttccttata actcttattt tcattagtag atgttactgt agattcaact gttctgttgt
     2101 ctaattgtga attggaacga atagtaccat tagagctgat attattaaca cttaacgaat
     2161 tatctaaacc attagtggtt gaattagagg caatcatttc agcagaacga ttctgattaa
     2221 cagttggtga attatctaaa tcattagtaa ttgcattaga agactctttt gtagccatcg
     2281 gtgaagaact agtaacaact tcatccgata aaataccttg gcttcccaaa attgaaattg
     2341 ccaatagtac cgagcaagtc cccaccttta atttacgaat actgaatacc tcattaggaa
     2401 caaaatattt catcagaacc tccaattttt ttactatttt taacaattga ttattacttt
     2461 tcttaaaata gatagaatga caccgctgtc attatcttta tcatatattt tccaaattga
     2521 attgtcaagg aataacacaa gaaaatatta aaatttatac tcttcggaaa tctcttcaaa
     2581 ctaggtcagt gccgccttgc cctaagtcta ggttactgac ttggtcagtt ctatagtaga
     2641 ctgaaactat aatagtacac ctctacttct aaaacattgt tagaaatcga tttgactgtc
     2701 ccgatcgatt tgtcctattc ttatttcctt ttactatatc tacaacctca aagcagggtt
     2761 ttgagctatc tatggccaac ttcctagttt gctctttagc cttccattca aaagtgatgc
     2821 tatctttctt agcttgaata taaaatatcc catttactat atttaaattt attgatatgt
     2881 tgtaaattat aaatgaaaga acaaatacct tgtcatacaa gcattcgcca gggatattta
     2941 catgaatatc gctcatatgg cggattgaaa ctaaaacact acaatatatt tcttaaatag
     3001 accttctata aaagctagat ttaacctcga taaaaataga tgcagtgctt ctaaaatact
     3061 ggaatagggc atataggtaa tagtagacaa gtgttttata gattgtctcg caggagatct
     3121 aatgatgtat agcaagcatc actaaacata tagaatattt gcattattat aatatcaaca
     3181 tgttataaat tctatcatgc aaaagaatga ctagaacatg aaagacaggc acaaaacttt
     3241 gaacaatatt ctgaaaacaa aaaaaagacg cgagtttcca caatctcact catggaaact
     3301 cacgtctttc aaaaaatagg gtgaattgaa aactagaaca agacactaga ttttctaaat
     3361 gatgtctagt aaggattcta aatgctacac caaattgctc acatcttatt tcaaaccacg
     3421 ggactcccac aagaaaggaa aatcctataa aaattctctc tctgaggaga aagaggcctc
     3481 aactacaggt gtaaactatt atcaattgaa aacaacagtt tttacactca attagacttt
     3541 ttagggacag gatcactttc gcttgactgt agtttgtcat ttttttgata aagttagcac
     3601 tttttcagaa actgttttga aagtctcaat gatatagtct acttcttcat cgcttaattt
     3661 agtatgaaga gggagggtaa tttcattctc aaagaaggca taggctttag gatagttcgt
     3721 catatcaaat ccaagattct tataggctgt caagagagga agcggtttgt agtgaacatt
     3781 acttgcaatt cctgctttag ccaattcttg gatgatgagg ttgcgttctt ctaggcttgc
     3841 tccttctaca cgggtgatgt agaggtggcg tgaagattcg acagtttcag tcttgtgtgc
     3901 caaaggatgg atgcgagaac ctgcaaaacc actatcatag cggtccacaa tgtccttacg
     3961 gcgttgcaac aaacttggat agcggtccaa ttgtaccaaa ccaagtgaag ccatgatatc
     4021 ggtcatgttg cacttatagg ctggtgtaac gatatcgtat tcccatgacc ccagttgcat
     4081 cttggcaaga gcatccttag tttgcccgtg aagggaaagg atttggaatt ccttgtacat
     4141 ctcttcgtca tcaatcactg gattggctct ccaagtcgca cttccacctt ctgccgttgt
     4201 aaagttctta acggcatgga atgagaagga agtaaagtca gcgatagaac cagaaggttg
     4261 tcctttataa gtagatccca aagcgtgggc actatcagag acaatgacaa tacggttaaa
     4321 ggccttttgc cacttgcttg aagcagtaaa gaagtcacgt tttttctcca cgacttggaa
     4381 caaacggtca taatcgcaaa caatccctgc gagctctact gggataatca ccttagtttt
     4441 ctcagtgata gcttgctcaa gcaggtcata gtccatctca aacgtatctg cttggatatc
     4501 caccatgaca ggggttgctc ccacgtgcgt aatgacacta catgaagccg tataggtcat
     4561 ggctggaacg atgacttcat caccaggtcc cacttccaaa acgcgtaaaa tcaactccag
     4621 agcggctgtc gcagagttga gacaaacagt cttaggtgtc tgtgtgtaaa gagacaagcg
     4681 gcgctccagt tcttttgttt taggacctgt tgtgatccaa ccagaacgca gggtatccgc
     4741 tacttcagca atttctgctt ctgtgatatc aggcggtgaa aatggaatat tgtaatttgg
     4801 cattgatttg ctccttttat ctgtactcat tttcttatga ctactttatt ttagtacctc
     4861 aaacacggtt tgaaacatga ttttgatgtc cccaaagaaa ctaaactctc ggagataggc
     4921 gaggttatag tgcatctttt caggaagaac atgctccaca taggcctgat caactgacag
     4981 acctttctcc gtcatttgac tgatgatggt gtcctcatcc ttgtagttga tgctggctgg
     5041 agaggtaatc cctgcttgca agagcaaggt tgccatcatt tcagggctat actgctctgt
     5101 ataacgtggc acttcaggtc gtgtaccgac aaaggacatc tcacctttaa ggacattgac
     5161 caactgaggc agttcgtcca aacggacacg tcggatgaaa tttccaacct tggtaatgcg
     5221 gctatcgtta gcagaagtca ccagacttcc ttttttatcc gcatccgtca ccatggtacg
     5281 aaacttccaa atcttgaacc gacggttgta ctgggtcaca cgctcttgct tgtaaatcac
     5341 tggccctttg ctatccaact tgatccaaat gctcaagatg agaaagatgg gagaggtcag
     5401 aaccagtaag accaaggcca aaacccagtc caagcaacgc ttgaaaatca gcgaaccctt
     5461 ccttttagag acaagctggt agtaagactc aacctcgctt gatttcattt ccacaggcaa
     5521 gtcttcccat ttcagcatgc tgttctcctt tgtttttatt atactatttg tcaacatttt
     5581 tcattatacc acaaaatgga aaaggcggtg aaagaaatct gtaatttgaa ggatttcctt
     5641 ctagtactca atgaaaatca aagtacagct ttgagattgc agataaagct gacatggttt
     5701 aaagagattt tcaaagagta tcggccatgg cccctgcctg caaactatac atcttgtgat
     5761 aggttcctcc cagagccaag agttcctcat gggttccact ctcgataatg cgtcccttat
     5821 ccaagacata gatgcagttg gcatcttgaa tagtagaaag gcggtgagcg atagcaatag
     5881 ttgttcggcc ctgtctcatc ttcgccagag aagcttgaac caagctttct gtttcagagt
     5941 caatattggc tgtcgcttca tccaaaatca ggattttagg ctggctggcg actgttctag
     6001 caaaggcaag aagctggcgt tgcccagtag agaagctcaa accacgctcg gaaacagggg
     6061 agtcgtaccc ctgaggaagt tcttgaataa aggaatctgc atccacaaag gctgccgcag
     6121 cctgaacctg ctcatcactg gtttcttggt acatggcgat attggactta atagttccat
     6181 gatagaggaa gggttcctgc aagaccaaac cgatgttttt tctcagctct tcttgactga
     6241 aatccctgat atccacatca tccaagagaa ctctccctga ctggaattca taaaagcgca
     6301 tgaggacatt gataatagac gatttccctg aacctgtatg acctacaaag gcaatggttt
     6361 cacccttatt aacagagaaa gaaatgtcat ccagaatcgg atgtttaccg tcatatgaga
     6421 aacacacatg ttcaaaacgg atattgcctt cttggacttt ggcttgccca ttttcttgaa
     6481 gaggttcata ggtcctctcg tctatcaggg caaagacacg acctgcagaa accatagccg
     6541 tttgcagagt tgaaaagttt tgcgtcacct caatcaaggg gtcaaaaagg cggttgatgt
     6601 actggataaa ggcatacatg gtcccgaccg ttatcccgat agaaaaacca cggtagccaa
     6661 agtaggccat caagactgca tagcctagaa gtttcagcaa actcatggca ggtctcaaaa
     6721 agagggcatc caaggctaca gaacggttgg cgtagaccaa gtgttcttgg ttgatttcat
     6781 caaattctgc ctgcaggcgc ttctcttgat taaaagcctg aataatcctg attccctcga
     6841 tattctctgc cagcttacta ttgatatctg acaagagact tctggttttc tcgatgattt
     6901 tcactgactt ttttcgatag agattgacca aaaggaaaat caaagggaga aagagcaaga
     6961 ctaaagccgt caaacgaaaa tccagcacca acatggtata aagggttgtc agaaagataa
     7021 aaactgctga gataaagctg gataaaatcc cagaaaacat atcactaatc gtctcggtat
     7081 cgttggtcaa acgagaaacg atagaacctg ctggcgtctt gtcaaagtaa gacatgccca
     7141 gtttctccat attggcaaag gcatcccgac gaatatccct aacaatactg taagacacgc
     7201 gcgcaaagag aagattgcct acatactgaa ctacagtttg taggatgtag agaccatagt
     7261 agaccagcaa aacggtaacg gctagttggt taagattgct gagatactgg tcgataaagt
     7321 gggaagccac gaggggtatg acacttttaa tgaccgtcgt cgctaggaga aaactgagtg
     7381 ccaaaaaggt caggagtcta taaggcttga gataagacat caagcgcttc aatacagccc
     7441 attgttcttg tttattctgc atcttcttct cctttcattt ctaactgctg agactggtag
     7501 gtttgggcat accagccatc catcgctagc aagtcttcgt gcctgcctcg ttcgataatt
     7561 tgaccatttt gtagaactaa aataaaatct gcatggacaa cagcactgag gcgatgggca
     7621 gtgataatgg ttgtcttgtc ctttcgcgtc tccttgaggt tgtcgataat cgcatactct
     7681 gtcttggcat ctacggcgga taaggaatca tccaaaatca agatatcagg gtctaaaatc
     7741 atagcccgac tcatagccaa ccgttgcttt tgaccaccag aaagactgac tcctttttca
     7801 ccaatcagcg tatcaaatcc ttgaggcatg tctacaatat cttggtaaac tcgggctagc
     7861 ttagtagctt cctcgaccgc tgaaaggggc aagttaggat tgccaaagcg gatattgtct
     7921 aggattgaag ttgcaaagag aaactggtcc tgaggaacat agcccatgag actgcgaagg
     7981 tctgtcagac gatagtcccg aatatcgtga ccgtttagat aaatggcacc cttatccaca
     8041 tcgtattcac gcaagaggag cttgattaag gacgttttcc cagagcctgt ctgcccaacc
     8101 aagcccagtg tttgcccttt tgccaaacta aagtgaatat ccgtcagtgt ttcctcattt
     8161 tcaaaagcaa agctgtcaat ggcatactcc aaacacccat tttcaatacc atccagagga
     8221 aactcagggt cttgtacagg agattcctga gacaaaagat tttcaatccg ctggtaagaa
     8281 accttccctc gctgagtagt attaaagagg aagccgatgg ccataagagg ccagaccagc
     8341 atatccaaat agctgataaa ggtgactaga ttcccaactg taatctgccc ttcctgaacc
     8401 atcaaggagc caaccaaaag cgttaaaaca taggacgaac caacaaacac gagaaccata
     8461 gggtcaaaga gactatcata tttcatggtt tgcaggttct tttggaaggt taattcattg
     8521 actgcctgaa aagacttcaa ctcgtctgcc tgataaccga aagacttggt cactttgata
     8581 cctgatacgg actcctgtac cttgttattg agttcagaaa aagcagcttg ggattcgcca
     8641 aaggccttat gagtctttct ccctaggcga ctagtcgcat aggccatgaa aggtaggggg
     8701 agaatggcaa caagagtcat ctgccatgag atgctaaaga gcatggtcaa caaagtcacc
     8761 agagccgtga tagaggcatc caccgcagac atgacaccgc cacctgctaa acgagtcaag
     8821 gcattgatat cattggttgc gtgtgccatc agatcacccg tccgataggt ttgataaaag
     8881 gctgatgaca tttttgtgaa atgcttaaac aagcgagacc gcatgatctg tcccaagcaa
     8941 taagaggtcc caaggatata catacgccac acatagcgca aatagtacat accaaaggct
     9001 gcaagtagca agtaaaatag gctaagaagg aggtcctgct gggttaattg ccccgatgtg
     9061 atggcatcaa tgacccgccc cataaccata ggaggaatga gattgagaac ggaaaccaag
     9121 accagggcca caatcccgac tagataacgg cgtttttcta acttgaaaaa ccaccaaagt
     9181 ttttgaataa tggacataaa atccctttct gattgcaaat ggaaacctga agccaatact
     9241 caatgaaaat caaagagcaa actaggaaac tagccgcagg ctgctcaaag cactgctttg
     9301 aggttgtaga tagaactgac gaagtcagta acctacatac ggcaaggcga cgttgacgcg
     9361 gtttgaagag attttcgaag agtacaagac cccaggtttt tcttattcat aagttacgac
     9421 tgtaacagca cccttgtcat attcagcaat aaagatattg gctacattgt catgcccttg
     9481 tttactgagg ttatcaagca accactcttc gctacgacca atcgattcca agacatctac
     9541 ttgaatcaca ccgtcagtca caactggata cttagaattt tcatctccca tttgcacaac
     9601 gatgagttgc ccattttgct cttgcacagc tcgtttgact tgcttcatct ggaaaatccc
     9661 ttggccacga agtttgaggg ctacatccga tgcagacaaa ccaactgaac gacaggctta
     9721 tgggtcaata ttcccatttt tgataaggag agttggctta ccatcaatca aacgtttcac
     9781 aaagtgaaca ttgttgttga gctatttgag agtcaagacc agtttgatta aaatttcgat
     9841 ataattaagt gtcatttgtt cacatccacc agttcaattg cgtctgtctt atacaattcg
     9901 actttctcta acaggtactt gtctggctca cttccgttta gggcacgata atagcgatct
     9961 cccaccttga taagtgcgcc atctgtgttt gtggaagtat taacatagac ttctgacttg
    10021 tctactccca aatctttgga aacaacctcg atgaaatgaa gtgaagtttg aaatttattg
    10081 ttagaaactt gattgttttg ataagtcgtg atgctgacca aaagcagagc taaataaggc
    10141 cagagctgaa atcatgacca actcacgaaa ttcggttccc tttttatcat ggtatgcctt
    10201 gaaagcaaaa aaactgtcat agctaataga acaatcccaa agccaaccat gataccattt
    10261 tgctgaccga tttggctgag tacatagtca taagagtaga atttcatgta ttttcactcc
    10321 ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa ccatacgttg
    10381 gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa ggtaacttta
    10441 tgaaacttat ctcatggaat attgattccc taaacgctgc cctaactagt gactcagctc
    10501 gtgccaaatt gtcccaagaa gtcctacaaa ccttggtcgc tgaaaatgct gatatcattg
    10561 ctatccaaga aaccaagctt tctgccaaag gacctacaaa gaaacacgtg gaaattttag
    10621 aagaactctt cccaggctac gaaaacacgt ggcgctcttc ccaagagcct gcccgtaaag
    10681 gctatgctgg aaccatgttc ctttataaga aagaacttac acccactgtc actttcccag
    10741 aaatcggtgc cccttctacc atggacttgg aaggccgcat catcactcta gaatttgatg
    10801 catttttcgt gacccaagtt tacacaccaa atgctggcga tggtcttaaa cgcttggaag
    10861 aacgccaagt ctgggatgtt aaatatgctg agtatttggc tgaactagac aaagaaaaac
    10921 cagtccttgc gaccggtgac tacaacgtag cccacaatga aatcgacctt gcaaatcctg
    10981 ctagcaaccg ccgttcacct ggatttactg acgaggaacg tgctggattt accaacctat
    11041 tggcaactgg atttactgat accttccgcc atgttcatgg cgatgttcct gaacgctaca
    11101 cttggtgggc acaacgcagc aaaacttcta aaatcaacaa tacaggctgg agaatcgact
    11161 actggctcac aagtaaccgt atcgctgaca aggtcactaa atctgatatg attgactcag
    11221 gtgctcgcca agaccataca ccgattgtct tggaaattga cttgtaagga ttttctatat
    11281 ggactacaat gcggtcattc ccgagttgct tgtatcgaat atcgaacagt cccggtcctt
    11341 ctactgtgat ttactgggtt ttaggattga ataccaacgt ccagaagaaa actttctctt
    11401 tctcttgaag agtgtcaact aatgttagag gagggaacaa aggatcaact agctgaactg
    11461 acctatctat ttggtcgtgg agtcaatctc tcctttggca taaaggatgt ttcaaaactc
    11521 tatcaaagag tgatgaaggc aaactatcct atttatcgtc ccttgaccaa aagaaagttt
    11581 cgtgtcagtg atcactatat ctatcctcat gaatttgcag ttttggatcc agatagctat
    11641 tttttaagat ttagcgagta gaataataaa aattgggaaa agtctttaaa gttagaaaaa
    11701 ggcatattgt caggtgtcta aaaacttgat agtatgcctt ttatgatgga aaaatcttct
    11761 aatactcttc gaaaatctct tcaagccacg tcaacgtcgc cttaccgtag gtatatgata
    11821 ctgactctgt caattctatc cacaacctca aaacaatgtt ttgaggttgt ggatagcttc
    11881 ctagtttgct ctttgatttt catttagtat aaatgttagc ttacaatgga gtttttgttc
    11941 acccctctct tctgtttgtt cgttttttaa accaaaatac taacaaaata gttgatttct
    12001 aaagttattt agtgtaaaat aaaaacattt gctcaagcct atttaaaatt gaatatcgtt
    12061 ttacttgttt atgtcgtgaa ttggcacgac gtttctacaa ggtgccggaa cacctaacaa
    12121 taagtaagtc agcagtgaga tatggccgtt tttgccatgt ctatttgggg gacttactta
    12181 gagattaagt aggtcttttt tgaatatttt taatatttcc cttaattagt gcggacggga
    12241 ggtgaaatta tcctgtgaat aatttcagga atccagggaa tttcatccct aatttttgag
    12301 cccctagctc tttcatttct aggcttaggc taaaatagtt ccccgaacta ttttactctc
    12361 aaaaatcccg tcatagacaa taacaagatt attgtctatg ataccactac aacgggaaat
    12421 atttgataag actcgcttcg ctcgtaatag ttttatcaaa tatatagtat tagcaaaagg
    12481 gatcactata gaaacattta aacaacaagt aaattaactt ttagacttta ggaggtctta
    12541 tgaaattatt agaagaacgc atcctcaagg atgggcatat cttgggtgat aacatcctca
    12601 aggtagattc ctttttaacc caccaagttg actttagctt gatgcgagag attggtaagg
    12661 tttttgcgga aaaatttgct gctactggca ttaccaaggt cgtaaccatt gaagcatcgg
    12721 gtattgcccc agccgttttt acagctgaag ccttaaacgt tcccatgatt ttcgccaaaa
    12781 aagctaagaa catcaccatg aacgaaggca tcttaactgc tcaagtctac tcctttacca
    12841 aacaggtgac cagcaccgtt tctatcgctg gaaaattcct ctcaccagag gacaaggttt
    12901 tgattatcga cgatttcctt gctaatggcc aagctgctaa aggcttgatt caaatcatcg
    12961 aacaggccgg tgccacagtc caagctatcg gtatcgtgat tgagaaatcc ttccaagatg
    13021 gccgtgattt gcttgaaaaa gcaggctacc ctgtcctatc acttgctcgt ttggatcgtt
    13081 ttgaaaatgg tcaggtcgta tttaaggagg cagatctcta atgcaaactc aagaaaaaca
    13141 ctcgcaagca gccgttcttg gcttgcagca cttactagcc atgtactcag gatctatcct
    13201 ggttcccatc atgattgcga cagcccttgg ctattcagct gagcagttga cctacctgat
    13261 ttctacagat atcttcatgt gtggggtggc aaccttcctc caactccaac tcaacaaata
    13321 ctttgggatt ggactcccag tcgttcttgg agttgcattc cagtcggtcg ctcccttgat
    13381 tatgattggg caaagccatg gtagtggcgc tatgtttggt gcccttatcg catctgggat
    13441 ttacgtggtt cttgtttcag gcatcttctc aaaagtagcc aatctcttcc catctatcgt
    13501 aacaggatct gttattacca cgattggttt aaccttgatc cctgtcgcta ttggaaatat
    13561 gggaaataac gttccagagc caactggtca aagtctcttg cttgcagcta ttactgttct
    13621 gattatcctc ttgatcaaca tctttaccaa aggatttatc aagtctatct ctattttgat
    13681 tggtctggtt gttggaactg ccattgctgc tactatgggc ttggtggact tctctcctgt
    13741 tgcggtagct ccacttgtcc atgtcccaac tccactctac tttgggatgc caacctttga
    13801 aatctcatct attgccatga tgtgtatcat cgcaacggtg tctatggttg agtcaactgg
    13861 tgtttatcta gccttgtctg atatcacaaa agatccaatc gacagcacgc gccttcgcaa
    13921 cggttaccgc gcagaaggtt tggcggtact tctcggagga atctttaaca ccttccctta
    13981 caccggattt tcacaaaacg ttggtttggt taaattgtca ggcatcaaaa aacgcctgcc
    14041 aatctactac gcagctggtt tcctggttct ccttggactg cttcctaagt ttggtgccct
    14101 tgcccaaatc attccaagct ccgtcctcgg cggtgccatg ctggtgatgt ttggttttgt
    14161 atctattcaa gggatgcaaa tcctcgcccg agttgacttt gctaacaatg aacacaactt
    14221 ccttatcgca gctgtttcaa tcgctgcagg tgtcggtctc aacaacagta atctctttgt
    14281 cagcatgccg acagccttcc aaatgttctt ctcaaacgga atcgtcgtag ccagcctact
    14341 cgctattgtc ctcaatgccg tattaaatca taaaaagaaa taagaaaaag aggtgcgagc
    14401 ctcttttttg tttatcacaa attgattata aatacaatca atcccaattc ccatctaatt
    14461 ga
//
LOCUS       DAVLDI010000053        14372 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLDI010000053 DAVLDI010000000
VERSION     DAVLDI010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14372
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.053"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(562..784)
                     /locus_tag="VXD01_001764"
                     /pseudo
     CDS             complement(562..784)
                     /locus_tag="VXD01_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(942..1196)
                     /locus_tag="VXD01_001765"
     CDS             complement(942..1196)
                     /locus_tag="VXD01_001765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0602115.1"
                     /translation="MGTKIGISKNTIGNYEKRVRSTKKNTIFDLVKVFSSLIDALFSP
                     VQKDSPSDIQSIYDQRAPPRQGKVLTYAERQLYDQKNEVS"
     gene            1632..2504
                     /locus_tag="VXD01_001766"
     CDS             1632..2504
                     /locus_tag="VXD01_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV0602116.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLDTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2653..2994)
                     /locus_tag="VXD01_001767"
                     /pseudo
     CDS             complement(2653..2994)
                     /locus_tag="VXD01_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3137..3448
                     /locus_tag="VXD01_001768"
     CDS             3137..3448
                     /locus_tag="VXD01_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602117.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            3452..4150
                     /locus_tag="VXD01_001769"
     CDS             3452..4150
                     /locus_tag="VXD01_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0602118.1"
                     /translation="MKKYFIGGLGNNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALLDTIFLENFGHELYTQAPK
                     EIASLMNEWLAYFL"
     gene            complement(4279..5094)
                     /locus_tag="VXD01_001770"
     CDS             complement(4279..5094)
                     /locus_tag="VXD01_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV0602119.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5091..5996)
                     /locus_tag="VXD01_001771"
     CDS             complement(5091..5996)
                     /locus_tag="VXD01_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV0602120.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKGFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(6326..6409)
                     /locus_tag="VXD01_001772"
                     /pseudo
     CDS             complement(6326..6409)
                     /locus_tag="VXD01_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            6453..8582
                     /locus_tag="VXD01_001773"
     CDS             6453..8582
                     /locus_tag="VXD01_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV0602121.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNVYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            8569..9018
                     /locus_tag="VXD01_001774"
     CDS             8569..9018
                     /locus_tag="VXD01_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV0602122.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            9077..9349
                     /locus_tag="VXD01_001775"
     CDS             9077..9349
                     /locus_tag="VXD01_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV0602123.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(9703..9894)
                     /locus_tag="VXD01_001776"
     CDS             complement(9703..9894)
                     /locus_tag="VXD01_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602124.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNILSQQQK"
     gene            10322..11080
                     /locus_tag="VXD01_001777"
     CDS             10322..11080
                     /locus_tag="VXD01_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602125.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            11082..13070
                     /locus_tag="VXD01_001778"
     CDS             11082..13070
                     /locus_tag="VXD01_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0602126.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTELTIFEKGQNRVQPKTIFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKTLILNDHQFSVKEEFNKDFIVKHVPNQF
                     NILTADYNYLVVPDLQAFLNQFPDSAIYNQFYGGMNVNVSEEEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSVLFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(13112..13756)
                     /locus_tag="VXD01_001779"
     CDS             complement(13112..13756)
                     /locus_tag="VXD01_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV0602127.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLGQLFSI"
     gene            complement(13728..>14372)
                     /locus_tag="VXD01_001780"
     CDS             complement(13728..>14372)
                     /locus_tag="VXD01_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0602128.1"
                     /translation="QDLLYPRKGKVLKKQASTNFKPAGQSIAQRPEAINLRLENGHYE
                     IDTVLLTRSKNYCLLVLTDRKSRHQIIRLIPNKSAEVVNQALKLILKQHKILSITADN
                     GTEFNRLSDVFSEEHIYYAHPYASWERGTNENHNRFIRRWLPKGTKKMTPKEVAFIEK
                     WINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRNRFKFCRSFKYPARRCSWC"
BASE COUNT         4359 a         2680 c         2962 g         4371 t
ORIGIN      
        1 aatcaaattc aaaccacgtc agcgtcgcct taccgtactc aagtacagct tgcggctagc
       61 ttcctagttt gctctttgat tttcattgag tatgaaataa gatatgcaca aattgattag
      121 aaagtcaaat gaatttctac aaatgtttta gcaatcgtaa tgtacttgtc tagattcgat
      181 ctgatatatt ttcgatttaa tgatatggta tttaaaacct tcaaagtagc ttgctccatt
      241 cttttactta cgtgagtgta gatgttattt actgttttag cgtttttgtg ttccactcta
      301 accattatag cattcttctc agctagtgta ctaaggagtg tgtgcctgaa aatatgggaa
      361 ctaaggggct ggtttatcgg tttctctagt ttagtatttg ccttttgcaa agtgatgtta
      421 aatgcctttc tctaaattta catatcacta ttgtttaaca aaatctaatc tattttaggt
      481 cacttattct ttttttgaaa tgtagaatga actttttcaa agtttttcga atcttttaaa
      541 atctgtttgt tttatatcgc cattctccct atatagcctg acaactttcc cgatggtacg
      601 aatatggttg ctttcgtcta ggtggatgtc ggggtatttg ggattgagtt tttttaaggt
      661 agccttggcg gagtttcttg acatagttag cgccgtctac ttggaagatg ccgatggtat
      721 tatagtcaat ctgtggggta ttcttgataa ataggtagtc gctgtttctt atctttggct
      781 ccatggactt gctgacgaca taagcgattg ggtcgtagtc gtctgggata atggaaactc
      841 catatctaaa tcgttgtcct gcatcgagcg gctacctgca gagataaact acctaacacg
      901 agagtaagta gtctgtctgt agtcgtccag tctgatgatt tttacgatac ttcgtttttc
      961 tgatcataca gttgcctctc ggcataggtc agaactttac cttgtctggg tggtgcccgt
     1021 tggtcgtaga tagattggat atcgctagga gaatcctttt gaactggaga aaagagggca
     1081 tcaatcaagc tactgaatac tttaactaag tcaaatatag tatttttctt agtagaccta
     1141 accctttttt cataatttcc aatggtgttt ttacttatac caatcttagt acccaattct
     1201 tattgagtcc aaccattact agtctatatt gttttatagt tgattgagtt tggaatagta
     1261 cgctgtagct gctaaaacat ttctaggaat taatttgcct ttcctaatag agttgttcat
     1321 atcttatttc aatctactat atttttcgcc tctaacaatc gcaatctctt ctttatctac
     1381 gaatgaaatc gctttctatt tttgtaagta aagcatcaca cgaaatccac gaaaatgaaa
     1441 acctttgttg tgttttcgta aaaaatttgt tgacagagca cgaaacgcct actataatta
     1501 aatcaagctt aaggaaataa caaaaaaaca aatcggaggg aaagacgatg aacacattaa
     1561 atgagaaagt aatcaatatc tgtaaagcag tagttaaaga aactttaatc caagacattt
     1621 aggagaaaga aatgaagaaa tcaagaaaat tagccacatt aggaatctgt tcagctttgt
     1681 ttttaggctt ggctgcttgt caacaacaac atgctacttc tgaggggacg aatcaaaggc
     1741 aaagcagttc agcgaaagtt ccatggaaag cttcatacac caacctaaac aaccaggtaa
     1801 gtacagaaga ggtcaaatct ctcttatcag ctcacttgga tccaaatagt gttgatgcat
     1861 tttttaatct cgttaatgac tataatacca ttgtcggctc aactggctta tcaggagatt
     1921 tcacttcctt tactcacacc gaatacgatg ttgagaaaat cagtcatctc tggaatcaaa
     1981 agaagggcga ttttgttggg accaactgcc gtatcaatag ttattgtctt ttgaaaaatt
     2041 cagtcaccat tccaaagctt gaaaagaatg accagttgct tttcctagat aatgatgcga
     2101 ttgataaagg aaaggtcttt gattcacaag ataaggaaga gtttgatatt ctattttcga
     2161 gagttccaac tgaggcaact acagatgtca aggttcacgc tgaaaagatg gaaacattct
     2221 tctcacaatt tcaattcaat gaaaaagctc gaatgctgtc tgtagtcttg cacgacaatc
     2281 tggatggcga gtatctgttt gtaggccacg ttggggtctt agtacctgct gatgacggtt
     2341 tcttatttgt agagaaattg actttcgaag agccctacca agcgattaaa tttgctagta
     2401 aggaagattg ctacaagtat ttggacacca agtatgcgga ttatacaggc gagggactgg
     2461 ctaagccttt tatcatggat aatgataagt gggttaaact ttaatagtgt tatgatatga
     2521 cagtaatctt aggattttta tttctatttt tgatgagttg gtgggttatt tcaatcgtta
     2581 atagccagaa accacgcaaa aatgaaacat ttattggcta tgtccaaaga tacgatattg
     2641 atgggaatgg ctatcaatca ttaccgtgtc ctcagaactg agaggagttc ttgaaatcgt
     2701 aaaaccactt tgaacaagag ttacttcaac ccattggctc cgacggatta agttgctttc
     2761 gtgaatacca aaatcagccg caatttcttc ataagtgcgg tattctcgca catattgaag
     2821 agtggccata agaaggtctt ctaggcttaa tttaggtttt cgtccacctt ttgcgtgttt
     2881 aagttgataa gctgttttta atacagctaa catctcttca aaagtcgtgc gctgaacacc
     2941 aacaagacgc ttaaatcgtg catcagttag ttgtttactt gcttcataat tcatagaact
     3001 attataccat gttttgtttc gcaggaaatc taatgctaaa atcttatcag tgagaagatt
     3061 tcttaaagtt tattctttgt agtttcatct gtattagtac ataatttaac ttagagaaaa
     3121 taggaggact aatcgaatgg aattaaaaga ttttacagaa aaagaacagg aaatgattaa
     3181 gaaaaggctt acaatgtcta atattagtga caaagaaact actgagaaga ttctggcgct
     3241 agtaccacaa gacttgatta agcgaatccc gttttttgtc agaaaacatg ctacaacacg
     3301 tacgattaaa cgcatttcaa ttgaacaccc tgaactctac gctgtagctc aaacaagtgg
     3361 tgagattcca gaaaaagaac gcgaagaatt gcgtcagatt atcacaacta tctttgaaca
     3421 aaagatgaat aagcatagta ttaagtagag aatgaaaaaa tattttattg gcggtttggg
     3481 aaataatgcc tatcatagca aggattttct tcaagaacta gattcgcagg tctattttct
     3541 aaatccatat gaaaagcatc ttcgagatga aacagaattg aaatcatggt ttaaaaatga
     3601 gattgtagag gaagaatcta tctgtctgat aggccattct cttggaggag atttagctcg
     3661 ttatttcgca tcggaatttg aagaagtaaa gaaactgatt cttttggatg gtggctatct
     3721 agatttagat aagattttac ctttggatac agagttagag gaaactaaaa attatatcaa
     3781 atctcaaatt gtttcggact tagctcttct tatttctaaa gagaagtccg aagcaaagca
     3841 ttggtcagaa aatatggaga aagctgtaag acagtcctat cactggaatg ttgagtataa
     3901 tagatatgag ttggctataa attatgaaaa tatagaagcg atactccgcc tacggagaaa
     3961 aatacaagct tttaagagag aagtgggaga taccttgttt attagtcctc gctatcctaa
     4021 tggagctaca tggagagagg aagccctact tgatactatt tttttagaaa actttggcca
     4081 tgagctttat actcaagcac ctaaagaaat cgctagtcta atgaatgagt ggctcgctta
     4141 ttttctatga gctacttgta ttgctggaaa tggtataaga tgaaaatcta caagtcacta
     4201 attttcatat aacaaaaaac gaacaggctc tttttctgtt attcagaaga gaacttgttc
     4261 gtttttatct tgattttctt aaaaagctct atatacatag ggattttctg gtttatcgac
     4321 tttggtaaag ctgtcgattt ccaaggttgg aaggttttgt ttgagttctt tatggtagtg
     4381 attgaccagt tttcctttgg ctgttatcca agtgttgttt tcatactgcc gggtattgcc
     4441 cttggtcagc aatccataga caccagaatc tgcgatacag tggataatgc cgaagcggaa
     4501 cagaaattgg ctattggcat gactggggtc gttatagaca aagcctgtaa actggattgt
     4561 cttgccctca aactcatctg gatagtcgta gatagcctcc atgacttcca tatagttttc
     4621 attagtgatc tgaatactat cttgggataa gtatttatcc gccgccgttc gcatttcctt
     4681 ttcataggct gattttgaaa aataagaact ggtatctggt ttcaaatatt ggcttgtcgt
     4741 cccttcgctt gtctgaatgg ctagatccgt tccttctgat agggggaaat gataaccttt
     4801 agcagaaacg gtctgagaat ccaagctaac agttgggaaa gttaagccga tgacaagtgg
     4861 aatagccaga agagaaatac tcgtcatctt ggctaatcgg ctgttcagat gactgtgggt
     4921 tttgacttgc ttcatccaga tatacaattg aacaatagcc aagataaagg aaagcaccat
     4981 ggaaatatag gccagatagg aatagtgcat gttgatgtac tggtttagtt tgcccgacag
     5041 atggaggtaa atagtcagtt caaaatagcc agctaaaact aaaaatcgaa tcataggatg
     5101 actccaatca agagagaata ggctaaaacg accagagtca caatcgtaat gaagtgacta
     5161 ataaatcgtg ctttcaagta atttttcatc atgagaatat ttttgatatc cagcattggg
     5221 ccaatgacga gaaaggccag aactggagcc aaaccgaaac tcgagagtag agaagcacct
     5281 ataaaggcat ccgcctcact acagagcgaa agaagaaagg ccaaaagcat caagagcagg
     5341 atggcaaaaa gaggagtcgc actgatagag gtcagaatcc gagtcggaac gtagacctgt
     5401 attatagaag caaagaggca gccaaatacc aaataacgcc ccgtatcaaa aaattcatca
     5461 atggcctgca caaagacttg aaaacctttt tttgcagaac tcaagtaaga aaaatcatgc
     5521 tcatgacaag ccagacgatt ttctttctga atcggttctt gccagaaaaa tcctagaaaa
     5581 attcctagta ttacagccac aagaatggaa cccagagctc gtaatagggc gacatggaag
     5641 gagttgccaa aggcagaata ggtcgcaaaa agaacaatgg gattgataac aggtgctgtc
     5701 acaagaaaag gaacggccgt gtaacttgga accttttttt ccagaaaacg attgatgatg
     5761 gggacgattc cacattcaca ggaagggaaa agtataccga caaaggtccc aaaaaagatt
     5821 ctcccccaac gatttcgagg gagaaaatga taaaccttgt caggtgtgat ataaacttca
     5881 atcagccctg agacaatgct tcctatcaga acgaagggaa gggcttcaat gataatggag
     5941 agaaaaatgg ctccagtttg aagtacacta gatgggagtt gttgaaaagc agtcatctag
     6001 tttttctttt ctgctttggc ttttttctct ttgtcatcag ggaaagtgac ttgtttcaaa
     6061 tcagggagtt tagcaaactc ttcaaacatc ttgtccaagt cgtctcgttt tgtaaatttg
     6121 acagccatag gtgtacctcg attctaaatt ctacctctat tatactatta ttttgcggaa
     6181 aagggagttt tttaatttgt tttcgatagt tgatactctt cgaaaatctc ttcaaaccac
     6241 gtcagcttcg ccttaccgta gtacggttac tgacttcgtc agttctatcc acaacctcaa
     6301 aacagtgttt tgagctgact tcgtcagttc tatccacaac cttaaaacag tattttgagc
     6361 agcctacggc tagcttccta gtttgctttt tgatttttat tgagtatgaa aaggattgga
     6421 gaaagctttc cagcttgtgg tataatagat ttatggataa aaaatatgaa aaaatctctc
     6481 aggatttggg agtgacgtta aagcaaattg ataccgttct aagtttgaca gctgaagggg
     6541 cgactattcc ctttatcgcg cgttatcgca aggacatgac tggtagtctg gatgaggtgg
     6601 cgattaaggc tattattgat ttggataaaa gtctgacaaa tctcaatgac cgtaaggaag
     6661 ctgtcttagc taagattcaa gaacaaggta agttgaccaa ggaattggaa gaagctatct
     6721 tagttgccga aaaattagca gacgttgaag aactctatct tccttataag gaaaagcgtc
     6781 gtaccaaggc aaccattgcc cgtgaagctg gactctttcc tcttgctcgc ttgattttgc
     6841 agaatatagt tgacttagag aaagaagctg aaaagttcgt ctgtgaagga tttgcgactg
     6901 gcaaggaagc cttgaccggt gcagttgata ttttggtcga agccttatcg gaagatgtga
     6961 ccttgcgttc tatgacttat caggaagtgc tgagacactc taaacttact tctcaagcca
     7021 aggatgaaag tcttgatgaa aagcaggttt ttcagattta ttatgatttt tcagagacag
     7081 ttggaactat gcaaggctat cgtaccttgg ctctcaatcg tggggagaaa cttggtgtct
     7141 tgaagatcgg ttttgaacat gcgacggacc gtattcttgc cttctttgct actcgtttca
     7201 aggtgaaaaa tgtttatatt gatgaagttg ttcagcaatc cgttaagaaa aaggtcttgc
     7261 ctgctatcga gcgtcgtatt cggacagaat taactgagaa agctgaagaa ggagctatcc
     7321 aacttttttc tgacaatctg cgcaatctcc tcttggttgc tccactgaaa gggcgcgtgg
     7381 ttcttggatt tgacccagcc tttcgtacag gtgccaagtt agctgtcgtg gatgcaacag
     7441 gaaaaatgct gacaactcag gttatttatc ctgttaaacc agcatcagct cgtcaaatcg
     7501 aagaagccaa gaaagattta gcagatttaa ttggtcaata cggtgtagag attattgcca
     7561 ttggaaatgg aacggccagt cgtgaaagtg aagcttttgt agcggaagtt ctgaaagatt
     7621 tccctgaagt cagctatgtt atcgttaatg aaagtggtgc ttctgtctat tctgccagcg
     7681 aacttgctcg tcaggagttt ccagacttga ccgttgaaaa acgttctgcc atttctatcg
     7741 cccgtcgttt gcaagatcct cttgcggaat tggtcaaaat cgatcctaag tcaattggtg
     7801 tcggtcaata ccaacacgat gtcagtcaga agaaactatc tgagagtctg gactttgttg
     7861 tcgatacagt ggttaaccaa gttggtgtca atgtcaatac agctagccca gctcttcttt
     7921 cacacgtagc tggactcaac aaaactatct ctgaaaatat tgtcaaatac cgcgaggaag
     7981 aaggaaaaat cacttcacgc gcccaaatca agaaagttcc tcgtctggga gccaaggcct
     8041 ttgagcaggc tgctggtttc cttcgtatcc ctgaaagtag caatatcctt gataatacag
     8101 gagttcaccc agagaattac actgcagtta aggaactctt caaacgttta gatattaaag
     8161 acctaaacga agaagcccaa agcaaactca agtccctttc agtcaaggaa atggctcaag
     8221 agctagacct cggtccagaa acccttaaag atatcattgc agatcttctc aaaccaggtc
     8281 gagatttccg tgattccttt gacgcacctg tgcttcgcca agatgtccta gatatcaaag
     8341 acctagtggt aggtcagaag ctagaaggtg ttgtgcgtaa cgttgttgac ttcggtgcct
     8401 tcgttgatat cgggattcac gaggacggct tgattcatat ttctcatatg agtcgcaagt
     8461 ttatcaaaca ccctagtcaa gtggtgtcag ttggagattt ggtgaccgtt tgggtcaaga
     8521 aaattgatac tgaacgtgaa aaagttaatc tgtcgctcct cgctccaaat gaaactgact
     8581 gattatgtca agcaggtttc actagaagac ttcgggagag cttttatcca tcatgtccag
     8641 tggaataggc gtctacgttc gacaggtggg cgatttttcc ccaaagatgg gcatctggat
     8701 tttaatccca aggtttatca gaaactgggt atggaggttt ttaggaaaat tgtccgacat
     8761 gaactctgtc attatcacct ttatttccaa gggaagggct atcaacacaa ggatcgggat
     8821 tttaaggaac ttttgaaagc agtggatgga ttacggtttg taccatcctt gcccaatagt
     8881 aactctaaac cactcaagct ttatcgttgt caatcctgcc agcaaaggta tcagcgcaag
     8941 cgtaggattg ataccaaacg ctatcgctgt ggactttgtc gaggtaaatt gcttctgata
     9001 aatcagcctg aggactgatg aaagccgagc ctccccgtga tatactatgt ctaacctagc
     9061 agaaagagga aatatcatga acagtaaatt ttataaaatg agacgcaatc gcatgatttc
     9121 aggagttctg gcaggtctgt cagacaagtg gaattttgat gttaccctag ttcgtttctt
     9181 gtttgctatt tttacagttg caaactttgg acttggcgtg attatctata tcatcctagc
     9241 ttctatcatg cctaccaagg aagaaatcga agcagaaatg tacggaacag gcccacgtaa
     9301 acgcaaagaa gcccaagcca ttgacgacaa tgaaggctgg ttttggtgag gttctacaga
     9361 agatttggaa taagcaaaaa gctttaaatc aatagtctaa actgcttgat ttaaagcttt
     9421 tttactttta tactcaataa aaatcaaagt gcaaactagg aagccagcca caggctgtaa
     9481 tttagtcggc aatgtgaagt tgacatagtt tgcactttga tttttgaata gtattaataa
     9541 tatttcgcca gcttcatcca caaactatag tggattggaa ctagaatagt acacctctac
     9601 ttctaaaaca ttgttagaaa tcgatttgac tatcctgatc gatttgtcct gttcttattt
     9661 cattttatta taaaagcagt aatttaaacg cagtttttta atctattttt gctgctgaga
     9721 caatatattt ttggaaaaat ggtggatgct gataacaact gataaccagc aaataacata
     9781 agcagtgccg gtaaattctg taccgataaa gtgtgtgtgt tcaactaaga gctgaccgat
     9841 gaatggagag agcagataga gaagtccgat gagtatatgt tctttgtgtt tcattaaagc
     9901 gcaccttctt tccttatagg ttgaacgact tgcaagtgtt aaattgaatg gtatgttatc
     9961 taggtaacct tactaaaatg ttagttcccg cttcctcctt ttcaaagtaa gccttttcac
    10021 acttatattt tacaacttta aaaataggaa atcaaatcat tttctaagta attttgctta
    10081 tatttcaccc aatcttacaa aaatgtaaga ttaaagtctc ttttgtaagg ttaggttatg
    10141 gcaagcggtc tttttttgat gtaaactaga ctcataaaga acaaaggagt aacatcatga
    10201 aacaaatctt acataagaaa actagaaaac caagtcacaa agaaattgag cgcgttcagc
    10261 tgggatgcac tatgatgcaa gctacatttc atttgatggg atattaagaa aggagattct
    10321 catgacactt ttagatgtaa aacacgttca aaaaatttat aaaacacgtt ttcagggcaa
    10381 ccaagtagaa gccctcaagg atattcactt taccgtcgaa aagggtgact acgttgccat
    10441 catgggtgag tctggttctg gtaaatcaac tcttctcaat attctagcta tgctggataa
    10501 accaagtcgt ggtcaggttt acttgaatgg aactgacacc gcaaccatta aaaattcaca
    10561 ggcctctagc ttccgtcgtg aaaagttggg ctttgtcttc caagacttta acttgctaga
    10621 tactctatct gtaaaggaca atatcttgct tccgcttgtc ttgtcaagaa gacctattac
    10681 agagatgatg aagaaattgg tggtgacagc tgagaatctg ggaataaacc aattacaaga
    10741 gaagtaccct tacgagattt ctggtggtca gaaacagcgt gtagcagtag cccgcgccat
    10801 catcacagaa cctgaaattc tccttgcgga cgaaccgaca ggagctcttg actccaagtc
    10861 atctgcagcc ttacttgatg tctttgatga aatcaatgag cgcggccaaa ccattctcat
    10921 ggtaacccac tcaacagcag cagctagcag agctaaacgt gtactcttta tcaaagacgg
    10981 cattctttac aatcaaatct accgtggaga gaagacagaa cgtcagatgt tccaagaaat
    11041 ctctgatacc ttgactgtca tggcaagcga ggtgaattag tatgtttcga ttaaccaata
    11101 agttagcggt atcgaacttg attaaaaacc gcaaactcta ctatcctttt gcgctggctg
    11161 ttctcttggc agtcactgtc acctatctct tttactctct aaccttcaat cctaagattg
    11221 cggaaatccg tggaggaaca accattcagg ctacacttgg atttggtatg tttgtcgtca
    11281 cccttgcgtc agccattatc gttctctatg ccaatagttt tgtcatgaag aaccgttcca
    11341 aggaactagg aatttatggc atgttgggct tggagaagcg tcatcttatc agtatgacct
    11401 ttaaggagtt agtggtattt gggattctaa ctgttggagc gggtatcggt attggagcct
    11461 tgtttgacaa gttaattttc gctttcctgc tcaaactaat gaaattgaag gttgagctgg
    11521 ttgctacctt ccagacgaaa gttgtcatta cagtgcttgt tgtcttcggt ttgattttcc
    11581 taggcctcat gttcctgaat gcccttcgaa tcgcccgtat gaatgccctc cagctctctc
    11641 gtgagaaagc tagtggagag aaaaaaggtc gcttccttcc tctccaaacc attcttggtt
    11701 ccataagttt aggaattggc tattatcttg cccttacggt aaaagatcct cttacagcct
    11761 taacaacctt cttcatagct gttttactgg ttatctttgg gacttatctc ttgtttaatg
    11821 cagggattac cgttttcctc caaatcttaa agaaaaataa gaaatactat taccaaccaa
    11881 ataacctcat atctgtttct aacttgattt tccgtatgaa gaaaaatgca gttggactag
    11941 ccaccatcgc tatcttgtca acaatggttt tggtaaccat gtcagcagcg acaagcattt
    12001 tcaattcctc agaaagcttt aaaaaagttc taaatcctca tgattttggg gtttcagggc
    12061 aaaatgttga aaaagaagac ttggacaaac tcttgagcca gtttgcaagt gacaaaggtt
    12121 ataagattaa agaaaaagaa gtatttcgtt acacttactt tgctgttgcg aatcaagaag
    12181 gaaccgagtt aactattttt gaaaaaggac aaaaccgtgt ccaaccaaaa acaattttca
    12241 tggtatttga ccaaaaagat tatgaaaata tgactggtca aaaactgtct ctatcaggaa
    12301 atgaggtcgg actctttgca aagaatgagg gagttaaaga acagaaaact ctaattctga
    12361 atgatcatca attttctgta aaagaagaat ttaataaaga ttttattgtc aagcatgtcc
    12421 caaatcagtt taatattttg actgctgatt acaattacct tgttgtacct gatttacaag
    12481 cctttttgaa ccaattccca gattcggcta tctataatca gttttacggt ggtatgaatg
    12541 taaatgtcag tgaagaagag caactcaaag tcgctgaaga atatgaaaaa tacttacaaa
    12601 agtttaatgc tcaattaaac actgaaggta actatgtgta tggtagcact ctagcagatg
    12661 ctagtgctca aatgagtgtc ctctttggcg gtgtcttctt tatcggtatt ttcctatcca
    12721 ttatctttat ggtcggaacc gttctggtca tctactacaa acaaatttct gaaggctacg
    12781 aagaccgtga gcgctttatt atcttgcaga aagtcggttt agatcaaaag caaatcaagc
    12841 aaaccatcaa caaacaggtt ttaactgtat tcttccttcc tttgctcttt gccttcctac
    12901 atctagcctt tgcctaccat atgcttagtc tgattttaaa agtgattggt gtactggata
    12961 cgactatgat gttgattgtg accttgtcta tctgcgctat cttcctcatc gcctatgtgc
    13021 tgattttcat gattacttca agaagttatc gcaagattgt gcaaatgtaa aaaagatacc
    13081 tcgacttcaa aatcgaggta tttcttgttt tctaaatgct gaaaagttgt ccgagcagga
    13141 aggtaactcc catagttaag agaccaatag caaggttccg aatcatagct gttttggttg
    13201 gggcttttcc aagtctagcg cttgtgtagc cagtgagaag aagggctaca ccgacgataa
    13261 ggacggtagc agggatgcgg taatcacttg gaaaaatggt cactgacagc attggaggca
    13321 aacttctaag gaaaaaggca acgaagctag aaatggcagc gtgccaagga ttggtaaatt
    13381 cttcatactc aatcccatat ttttcctcta ccagagcctt gagtggattt ttaagaaaga
    13441 tcttattggt caagagttgg gcagaagttt tgcattctcc attttggata taagcagcat
    13501 agagggattt tttggctagt tccctatctt ggtctaacaa gagtttttct cgcgaaacgg
    13561 cagcttcctc ggtatctttt ggagttgaaa cggatacata ttctccacca gccattgaaa
    13621 aggcaccagc taagatagcc gcaaatcctg ataaaaagat aatccagata ttggtcgtgg
    13681 cactggcaac cccgataacc acaccagcaa tggaaataat tccatcgtta gcaccaagaa
    13741 cacctgcgcg caggatattt aaacgacctg caaaatttga atcgatttcg tgatttgttt
    13801 ctgacgctaa atttcaagtt caagttagcc atccagaagt cttctctggg tgacttgtag
    13861 tccaagcatt ttttaggata gttgttaatc cacttttcga tgaatgcgac ttccttagga
    13921 gtcattttct tggttccctt aggtaaccat ctacgaatga acctgttgtg attctcatta
    13981 gttccccttt cccaagaggc ataggggtgc gcataataaa tgtgctcctc agaaaataca
    14041 tcagacaagc gattgaattc cgttccatta tctgccgtga tggaaagaat cttgtgttgt
    14101 tttaagatga gttttagagc ctgattgacc acctcagcac ttttatttgg aatcaatcgg
    14161 atgatctgat gtctactctt tcgatccgtc aagacaagca agcagtagtt tttcgatctc
    14221 gtaagtagaa ccgtatcaat ctcataatgc ccattctcca agcgaagatt gatagcttca
    14281 ggccgctgtg cgatggattg accagcaggt ttaaagttgg tgctagcctg tttcttaagc
    14341 acttttcctt ttctagggta aagcagatcc tg
//
LOCUS       DAVLDI010000054        14107 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLDI010000054 DAVLDI010000000
VERSION     DAVLDI010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.054"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            71..868
                     /locus_tag="VXD01_001781"
     CDS             71..868
                     /locus_tag="VXD01_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV0602129.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGVKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ANSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1016..1138
                     /locus_tag="VXD01_001782"
     CDS             1016..1138
                     /locus_tag="VXD01_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine sulfhydrylase"
                     /protein_id="HEV0602130.1"
                     /translation="MTRDFKFETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            1160..2200
                     /locus_tag="VXD01_001783"
     CDS             1160..2200
                     /locus_tag="VXD01_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV0602131.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILAIAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFFDIDNLEEVEAAIKDNTKLVLIETLG
                     NPLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSVTKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTRDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKGVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            2371..3645
                     /locus_tag="VXD01_001784"
     CDS             2371..3645
                     /locus_tag="VXD01_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV0602132.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3655..4533
                     /gene="truB"
                     /locus_tag="VXD01_001785"
     CDS             3655..4533
                     /gene="truB"
                     /locus_tag="VXD01_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV0602133.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4774..5076
                     /locus_tag="VXD01_001786"
     CDS             4774..5076
                     /locus_tag="VXD01_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV0602134.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5184..5822
                     /gene="udk"
                     /locus_tag="VXD01_001787"
     CDS             5184..5822
                     /gene="udk"
                     /locus_tag="VXD01_001787"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV0602135.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5950..7290
                     /locus_tag="VXD01_001788"
     CDS             5950..7290
                     /locus_tag="VXD01_001788"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV0602136.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEDLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLDSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7268..7480
                     /locus_tag="VXD01_001789"
     CDS             7268..7480
                     /locus_tag="VXD01_001789"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV0602137.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7477..8352
                     /locus_tag="VXD01_001790"
     CDS             7477..8352
                     /locus_tag="VXD01_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV0602138.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8345..9160
                     /locus_tag="VXD01_001791"
     CDS             8345..9160
                     /locus_tag="VXD01_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV0602139.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKGAVERAHSQFKNE"
     gene            9153..9584
                     /locus_tag="VXD01_001792"
     CDS             9153..9584
                     /locus_tag="VXD01_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0602140.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9591..11258
                     /gene="recN"
                     /locus_tag="VXD01_001793"
     CDS             9591..11258
                     /gene="recN"
                     /locus_tag="VXD01_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV0602141.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEEFMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLAAARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKVS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11260..11988
                     /locus_tag="VXD01_001794"
     CDS             11260..11988
                     /locus_tag="VXD01_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV0602142.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12067..13890
                     /gene="lepA"
                     /locus_tag="VXD01_001795"
     CDS             12067..13890
                     /gene="lepA"
                     /locus_tag="VXD01_001795"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV0602143.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(13971..>14107)
                     /locus_tag="VXD01_001796"
     CDS             complement(13971..>14107)
                     /locus_tag="VXD01_001796"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602144.1"
                     /translation="TRKLAAGYSKHSFEVVDETDEVSNHTYSKATLTWFEEIFEEYKN
                     "
BASE COUNT         4162 a         2587 c         3363 g         3995 t
ORIGIN      
        1 tacagaaaac gcttcctaaa acctaaagtt tgtgatataa ttatcaagaa aaaagattta
       61 ggagtttatt atgatttctt cagaatttat ctcaaagatt gaatttgctt gcaataagaa
      121 agaaagtctt tatagtcaaa gcaaatttaa gtatgcgatt cgttcgatgt tcgcaggtgc
      181 atttttaacc ttcagtactg ctgcaggtgc agttggggct gacttgatta ataaaattgc
      241 accaggtagt ggacgcttcc tctttccatt cgtttttgct tggggcttgg cctacattgt
      301 ttttttgaat gccgagttgg tcacttcaaa catgatgttc ttgactgctg gtagtttctt
      361 aaaaaaaatc tcttggagaa aaacagctga gattttacta tactgtacct tgttcaacct
      421 tatcggagcc ttgatagcag ggtggggctt tgctcattcg gcagcctatg cgaatctgac
      481 acacgatagt ttcatctcag gtgttgttga gatgaagtta ggccgctcaa atgaattggt
      541 cttgcttgag gcgattttgg caaatatttt cgtaaatatt gcgattctgt catttatttt
      601 ggtcaaagat ggtggtgtca aactttggct tgtgttgtca gctatttaca tgtttgtatt
      661 cttaacaaac gagcacattg cggcgaactt tgcttctttc gcgattgtga aattcagtgt
      721 tgctgcgaat tcaattgcca acttcggtgt tggaaatatg cttcgccact ggggtgtgac
      781 tttcatcgga aactttatcg gaggaggcct cttgatgggt cttccatatg ccttcctcaa
      841 taaaaacgaa gatacttatg tagattaaga aaatgagcac gattgagtcg tgcttttttc
      901 attttcaaaa taaggtaata gctatttctt atatcaaaat atagaaaact gatatttgta
      961 aactataact caaggtgcta caatatcctt aataaaataa tatggaggtc accttatgac
     1021 tcgtgatttt aaatttgaaa ctctacaact acatgctggt caagttgtgg ctccagctac
     1081 taagtctcgt gcagtgccga tttatcaaac aacatttttt gtttttgatg acacgtagga
     1141 aggtgccgat ctgtttgcct tgaggaaacc agggaacatt tatactcgta tcaccaatcc
     1201 tacaacagct gcccttgaag gtggtgttga agcgctagca acagcatcag gtatgactgc
     1261 agtgacttat actattttgg cgattgccca tgctggtgac catgtagtgg ctgcttcgac
     1321 tatttacggt ggaaccttca atcttttgaa agaacccctt cctcgttatg gtatcacaac
     1381 aacctttttc gatattgata atttggagga agtagaagca gctatcaaag acaataccaa
     1441 gcttgtcttg attgaaacct tgggtaaccc cttgattaat attccagacc tggaaaaact
     1501 ggcagagatt gctcataaac atcaaatccc acttgtgtca gacaatactt ttgcaacacc
     1561 ttatttgatt aacgtcttct ctcatggcgt tgacattgcc attcactctg tgactaagtt
     1621 tatcggtggg catggtacaa ctattggagg aataattgtc gatagtggtc gttttgactg
     1681 gacggcttca gggaaattcc ctcaatttgt tgacgagggt ccaagctgcc acaatttgag
     1741 ctatactcgt gatgtgggtg cagcagcctt tattatagct gttcgagttc aattgcttcg
     1801 tgatacaggt gcagccttgt caccattcaa tgctttcctc ttgctacaaa gacttgaaac
     1861 ctcttcactt cgtgtggaac gccatgtaca aaatgctgag acaattgttg attttcttgt
     1921 caaccatcct aaggtagaaa aggtaaatta tccaaaactt gcagatagtc cttatcatgc
     1981 cttggctgag aaatacttgc caaaaggtgt cggttcaatc tttaccttcc acgtcaaagg
     2041 tggcgaggaa gaagcacgca aggtcattga taatttagaa atcttttctg accttgcaaa
     2101 cgcggcagat gctaaatcgc ttgttgtcca tccagcaaca accactcacg gtcaattgtc
     2161 agaaaaagac ctagaagcag caggtgtcac accaaactaa attcgtttgt caatcggtct
     2221 tgaaaatgta gaagatttga ttgaagactt gcgcttggcc ttggaaaaaa tttaaagtaa
     2281 aagaagataa acagtgggct tcgactcact gtttttgatt ttccctcagg catgatataa
     2341 tggttaaaga agtctagaaa gaggaacgat atgaacgaaa tcaaatgtcc caactgtggg
     2401 gaagtcttta cagtaaatga gagtcagtat gccgaactct tgtcccaagt gagaacggca
     2461 gagtttgata aggaactaca cgataggatg aagcaggaac tggccttggc tgagcaaaag
     2521 gccatgaatg agcaacagac taaactggct cagaaggatc aagaaattgc gcaattacag
     2581 agtcagatcc aaaactttga tacagaaaaa gaattggcca agaaagaggt tgaacagaca
     2641 agccatgagg ctctcttggc taaggacaag gaagtacagc tcttagaaaa tcagttggct
     2701 accttgcgtt tggagcatga aaatcaacta caaaagaccc tttctgacct agaaaaagaa
     2761 cgggatcagg ttaaaaacca actacttttg caggaaaagg aaaatgaatt atctttggct
     2821 tctgttaagc aaaactacga agcccagctc aaggcagcta gtgaacaagt cgagttttat
     2881 aagaatttta aggctcaaca atctacaaaa gcgattgggg aaagcctaga acagtatgca
     2941 gagagtgagt ttaacaaggt tcgtagtttc gcctttccaa atgcttactt tgagaaggat
     3001 aacaaggtct cttcgcgtgg gtctaaaggg gactttatct tccgtgagtg tgatgaaaat
     3061 ggagttgaaa tcatttctat catgtttgag atgaaaaacg aagcggacgg aacagagaag
     3121 aagcacaaga atgcagattt ttacaaggaa ttggacaagg accgtcggga gaagaactgt
     3181 gagtatgccg ttttggtgac catgcttgag gctgataatg actactttaa cacagggatt
     3241 gttgacgtca gtcacgagta tgaaaaaatg tatgttgttc gtcctcaatt ctttatccaa
     3301 ttgattggtc tcttacgtaa tgcggcgcta aattccctaa aatacaagca ggagttggcc
     3361 ttggttcgcg agcaaaatat tgacattacg cattttgagg aagacttgga tgcctttaag
     3421 ctagcttttg ctaagaacta taattcagct tcgactaact ttggaaaagc tattgatgaa
     3481 atcgacaagg ccatcaaacg catggaagag gttaagaaat tcctgactac atctgaaaac
     3541 caactccgtc tagctaacaa caaattggaa gatgtctctg ttaaaaaatt gacccggaaa
     3601 aatccaacaa tgaaagcgaa gttcgaagca ctgaaggggg agtagaaagc aaaaatgaac
     3661 ggtattatca acttaaaaaa agaagcagga atgacctcgc atgatgcggt ttttaaactg
     3721 cgtaagattt tgggaaccaa gaaaattggt catggcggaa ccttggatcc ggatgtggtg
     3781 ggtgttttgc cgattgcggt tggcaaggcg acacgcatgg tcgagtttat gcaggacgag
     3841 ggtaagatct atgaggggga aatcactctg ggttattcca cgacgactga ggatgctagt
     3901 ggggaagtgg tcgcagaaac ccctgttttg tctcccttgg atgaaaagct tgttgatgaa
     3961 gcgattgcta gcttgactgg gcctattacc cagattcccc ctatgtattc ggcagttaag
     4021 gttaatggtc gcaagctcta tgagtatgcg cgtgctggtc aggaagtgga gcgtccagaa
     4081 cgtcaggtga ccatttatca atttgagcga acaagtccga tttcttatga tggccaactt
     4141 gcccgattca cttttcgtgt aaaatgcagt aaagggactt acatccgtac tttgtcagtt
     4201 gatttgggtg aaaagcttgg ttatgcggct catatgtccc atttgactcg tactagtgct
     4261 gctggcttac aattagaaga cgctcttgcc ttggaggaaa ttgctgaaaa agtagaggct
     4321 gggcaattag attttctcca tcctttagag attgggacag gtgaccttgt caaagttttc
     4381 ctaactccag aagaggctac agaagttcgc tttggtcgtt ttattgagct agaccaaacg
     4441 gacaaagaac tggctgcctt tgaagatgat aaattgttag ccattctaga aaaacggggc
     4501 aatctctata agccaaggaa ggtttttagc tagatcgttt aggaataaaa atcgggtgat
     4561 agataacaat tgcttgataa aaccccatac taatagtaga atggttttgg gaattataat
     4621 attccaattg ttgcgagttg taggtactca aataatctat atagaaattt agaggtgtga
     4681 aatgaagcaa tttaaaattc tttcagataa atatttagag tccattacag gttctggtgg
     4741 gaacttaggc ccaggatttg gtgtgataat tccatgatgc gaaatgagtt tcgagaaagg
     4801 gtggagcaac ttcttcaaca aaaagaaata aatgaaaata gtgagttgag tcacctgttt
     4861 cgtcttgcta tacaaaattt agacagaaat gaaaaatacc aatcggtcat ggccaatttg
     4921 agtcaagggt tgtcacttta cctcatgacg catcattacc aggcacctaa gtctgtcatt
     4981 gattttggtt tatggattgc caaagctcct agccaggaaa gagggagact ggctttcttg
     5041 cagatgcttg ctcaaaccct acagggcttt cgttaaaact gtcgaacatc agagggaaga
     5101 ctctggtgtt ttttgctgat gagactataa attttgtaaa aaatgtgata gaatagacga
     5161 cggataaaat aacggaggat agcatgcaaa atagaccaat cattattgga gtgacaggtg
     5221 gttctggtgg tggtaaaacc agtgtttcaa gagccatttt atcgcatttt cctgatgaaa
     5281 agatttccat gattgagcat gattcatact acaaggatca gtctcatttg acctttgaag
     5341 agcgtgtcaa aaccaactat gaccatcctt ttgcctttga tacagacttg atgatcgagc
     5401 agattaagga attgttggca gggcgtccgg tggacatccc gacctacgac tatacagagc
     5461 atacacggag tagcaagacc tatcgtcagg agcctcaaga tgtctttatc gttgagggca
     5521 ttttggtctt ggaggacaag cgtctgcgcg atttgatgga tatcaagatt tttgtggata
     5581 cggatgacga tgtgcgcatt attcgtcgta tcaagcgtga tatggaggag cgtggccgta
     5641 gccttgatag cgttattaac cagtacttag gtgtggtcaa accaatgtac caccagttta
     5701 tcgagtcaac taagcgttat gctgatatcg tcattcctga aggggttagc aataccgtgg
     5761 ctatcgacct gttgacgacc aagattgcaa agattttgga agaagctcga aacagcaaat
     5821 aatcacatgt ggaggccttg cctccttttt ctatttttcc ctcataatgg tacataaatg
     5881 gagattttta ggcatatttt tggtataata atacccatga aagagcaagt aaatgaatag
     5941 taggtggaga tggaaaagta tttatcggta acaactttga ccaagtatct gaaaatgaaa
     6001 ttcgataaag acccatactt ggaacgggtc tatttaactg gtcaagtttc caactttcgt
     6061 aaacgaccta ctcaccaata tttctcccta aaggatgacc atgcagttat tcaagcgacc
     6121 atctggtctg ggatttatca gaaattaggg tttgacctgg aagaaggaat gaagatcaat
     6181 gtgattgggc gtgtacaggt ctatgaacca agtggtagct actccatcat cattgaaaaa
     6241 gctgagcctg atggggttgg ggcgcttgcg attcagtttg aacaacttaa gaaaaaattg
     6301 acagaagaag acctgtttca agaacgcttc aagcaagctc tgccccaatt ttctaagaga
     6361 attggtgtag taaccagccg tagtggagcc gttattcgag atattatcac gaccgtcagc
     6421 aggcgattcc caggtgttga catccttctt tatccgacca aggttcaagg tgaaggggct
     6481 gcggaggaaa ttgctagaaa tattgcgcgt gctaatcaac gggacgattt ggatttgctc
     6541 attattggtc gtggaggtgg ttctattgag gatctctggg cctttaacga agaaattgtg
     6601 gtacgagcta tttttgaatc tcgtttgcca gttatctcta gtgtggggca tgagacggat
     6661 gtgaccttgg cagattttgt ggcagatcga cgcgctgcaa cgccaacagc ggcggctgaa
     6721 ctggcaacac ctgtgaccaa gttggatgta ttaactcatt tgcaaaatca ggaaaaacgg
     6781 atggcaacgg cagtccgaaa tgttctatct aagaaacaag aggctttgaa aaaatgcagt
     6841 cagtctgtta tctttagaca acctgagcgc ttgtatgacg gttatttgca acgcttggac
     6901 caactgcaac tgcgtttgaa acaaagtttg cgaactcgga tttctgataa caaacaatta
     6961 gttcaagcaa gaactcatca attagtacaa ttatcacctg ttaccaaaat ccaacgctat
     7021 caagaccgtt taggacagtt ggacaagctc ttagatagcc aaatggcgtt agtttatgac
     7081 gccaaggttg ctgaggccaa gcgactttcg gaagctttgc tcatgttgga tactagccga
     7141 atcgttgcgc gtggttatgc tattgtcaaa aaagaagagt ccgttgtaga ttcggttgag
     7201 agtttgaaga aaaaagacca agtaacgctt ttgatgcgag atggtcaagt agaattagag
     7261 gttaaagatg tcaaaacaaa agaaatttga ggaaaatcta gcagaactgg aaaccattgt
     7321 ccaaagtttg gaaaatggtg aaattgctct ggaagatgcg attactgcct ttcaaaaggg
     7381 catggtcttg tcaaaagagc tccaagctac gctggacaag gctgaaaaga ccttggtcaa
     7441 ggtcatgcaa gaagacggaa cagaaagtga ttttgaatga aaaagcaaga aaaattagct
     7501 cttgtcgagt cggctttgga agatttttat ggagaccagc agtttgcctc tagtttacgg
     7561 gagtctgttc tctattctat tcatgctggt ggcaagcgta ttcggccttt tctcttgtta
     7621 gaagttctgg aagccttgca ggttaccatc aaacctgctc acgcgcaggt agctactgcc
     7681 ttggagatga ttcatacagg gagcttgatt cacgatgacc ttcctgctat ggatgatgac
     7741 gattatcgaa gagggcggtt aaccaatcac aagaaattcg gtgaagctat ggccattttg
     7801 gctggagatg ccttattctt agactcatat gccttgattg cgcaggcaga tttgccaagt
     7861 cagattaagg tggacttgat tgccaactta tcccttgctt caggtagtct gggtatggtg
     7921 gcagggcaag ttttggatat ggagggcgaa caccagcact tgtctttgga agaacttcag
     7981 actattcatg ccaataagac tgggaagtta ctagcctatc ccttccaagc ggcagctatt
     8041 atagctgaat tgtcacctga aatgcaggtg aagctgaaaa ctgtgggtga attgattgga
     8101 cttgcttttc aagtcagaga tgatgtactg gatgtgacag ctagttttga ggaaatcggc
     8161 aagacacctc aaaaggatct gcaggcagaa aaatcaacct atcctgccct gttgggcttg
     8221 gaagagtcca ttgccttttg taaccaaacc ctggatcaag ctaatgaaaa attggaagaa
     8281 attgcccagc agcttccctt tgaaacagaa tcgattgtaa gtgtagtaga aagtttgaga
     8341 atcaatggct aaggaaagag tggatgtact agcttataaa caggggttgt ttgaaacgag
     8401 agagcaggcc aagcgaggtg tgatggctgg cctagtcgta gcagtcctta atggagaacg
     8461 gtttgacaag ccaggagaga aaattccaga tgataccgaa ttaaaactca agggggagaa
     8521 actcaagtat gtcagccgtg gtggtttgaa actggaaaag gccttgcagg tctttgattt
     8581 gtcggtggat ggcgcgacta cgattgatat cggggcctct actggaggtt ttaccgatgt
     8641 catgctacag aatagtgcca agttggtctt tgcagtcgat gttggtacca atcagttggc
     8701 ttggaaatta cgccaagacc cacgagttgt cagcatggag cagttcaatt tccgctatgc
     8761 tgaaaagact gatttcgagc aggagccgag ctttgccagt attgatgtga gtttcatttc
     8821 ccttagtctg attttgccag ccttgcaccg tgtcttggct gatcaaggtc aggtggtagc
     8881 acttgtcaaa cctcagtttg aggcaggacg tgagcagatt gggaaaaatg gaattattcg
     8941 agatgctaag attcatcaga atgtccttga atctgtaaca gctatggcag tagaggcagg
     9001 tttttcagtc cttggcttgg acttttctcc catccaaggt ggacatggaa atattgaatt
     9061 tttagcgtat ttgaaaaaag aaaagtcagc aagcaatcag attcttgctg agattaaagg
     9121 agcagtagag agggcgcata gtcaatttaa aaatgaataa aaaagaaaga cttgaaaaaa
     9181 ttagaagatt ggtgacagat tatcaaatcg gcacgcaaga agaaattgta gaacatttga
     9241 aagaagcagg tatcactgcc actcaggcga cggtatcccg agatatcaaa gagttaggta
     9301 ttgtcaaaat tcctttgaga gacaacacct atgtctacga attaccaaaa tcaatcgtaa
     9361 aaagtctgca actggctgaa gacaatatcg aatcggctga attgatggat aagatgatca
     9421 atctccaagt tattccagga aatacggctt ttgtaaaagc tcagttaatc gagacttttg
     9481 cagacaagat ttttagctgt ttgactgatg atagctcgat tttagtcatt gccagaagtg
     9541 gaagtctagc agaggaaatc tttgaacaag taaaaaattg gtaggtctat atgttacttg
     9601 aaatttcgat aaaaaacttt gccattattg aggctatttc cctcaatttt gaaaagggga
     9661 tgactgtcct gactggtgaa acgggtgcag ggaagtcgat tatcattgat gccatgaata
     9721 tgatgttggg agctcgtgcg acgacagatg ttattcgtca tggtgcacca aaggcagaga
     9781 ttgaggggct tttctcagtt gagaatagtc gtcttttaca ggaaattttt gatgagcaag
     9841 gtttagaatt aggtgatgaa attatcatcc gtcgggaaat cttgcaaaat ggtcgtagta
     9901 tcagccgtgt aaatggtcag atggttaatc tgtctgtttt gcgagctatt gggcaacatc
     9961 ttgtagatat tcatggtcag catgaccatg aggagttcat gcgtccccaa ctgcatatcc
    10021 agatgttgga tgaatttggc gatgccgctt tttgggactt gaaagaaacc tatcaaacga
    10081 gttttgatgc ctatcggaaa atgcgcaagc aggttctgga agtcaagaaa aaccaacagg
    10141 aacacaaggc acgtatcgaa atgttggaat ttcaaatggc agagattgag gcagcaaact
    10201 tgcaggctgg agaagacttg gatctcaatc aagagcgaga taaactcctc aaccacaaaa
    10261 atattgcgga tacactgacc aatgcctaca gtatgttgga caatgaagat ttttcaagtc
    10321 tggccaatgt tcgttcagcc atgaatgaca tggaaagtgt cgaagagtat gaccctgaat
    10381 accgtgaaat ttcaagctct ctgtctgaga cctactatgt tttagaagac attagcaaac
    10441 gtttggaagc tatcattgag gaccttgatt ttgatggcaa tcgcctcatg caggttgaga
    10501 atcgtttgga cctccttcat actattactc gtaagtatgg tgggactgtt gatgatgttt
    10561 tgctttattt tgccaagatt acggaagaat acaatctctt gacaggcaat aatctttcgt
    10621 ctgaggacat ggaagcagag cttaagaagt tggaagtcaa tcttgtcaat ttggcaggcc
    10681 aacttgctgc tgctcgtcat aatttggctc agcaactcga agctgagatt aaacaagaac
    10741 tgcaagatct ttatatggaa aaagcccagt ttcaggttcg ttttagtaag ggaaaattca
    10801 gtcgtgaggg aaatgaaatg gttgagtttt atatttcaac caaccctgga gaagacttta
    10861 aacccttggt taaggttgct tctggagggg aattatctcg tctcatgtta gccattaagt
    10921 ctgccttttc acgtaaagaa ggcaagacta gcattgtctt tgatgaggtg gatacgggag
    10981 tttcaggtcg tgttgctcaa gctattgctc agaaaattca taaaattggt cagcatggtc
    11041 aggttttggc tatctcccat ttgccacaag taattgcgat tgcagattat caattcttta
    11101 ttgagaaggt tagtaatgac cattcaacgg tttcgactgt tcgtctcttg acggtcgaag
    11161 agcgagtgga ggaagttgcc aagatgttgg caggtgatga tgtgacagaa gcagccctga
    11221 cgcaagccag agaattgttg agaaacaggg agaaataaga tgacagatta ttatgtaatt
    11281 ggagatgttc acggaaaagc tgggatgctg gaagaccttc tcaaaacctg ggatggtcag
    11341 acccagttgc tctttctagg tgatttgatt gacagaggtg aggatagtca ccgtgttctt
    11401 gaaatggtca aggacttggt ggacaatcaa ggggctatct gtttgtctgg aaaccacgag
    11461 tatatgtttt tgacttggct agatgaccca gaagaaagtt atgaccatta tcgtcgcaat
    11521 ggtggagata caaccattaa ctctatccta ggtcgtccct tggatgcacc agttgatgga
    11581 gtagaagatg ccaagcgggt tgccgctgaa gcgtcagact tggtcgaatt cattcgtcaa
    11641 atgccatttg tagtagagac agacaagtat atatttgttc acgcaggtat tgatttgact
    11701 ttggacgact ggcatgaaac aacagattat aaaaaagtat ggcttagaaa accattccac
    11761 ggagctgaaa atcatactgg aaaaaccatt gtcttcggtc atacaccggt ctatggtttg
    11821 ttacagcaag aacgcggtac atctgagctt tggactacag aagatggcaa gattggaatg
    11881 gatggaggag ctgtttatgg tggtgtcctt cacgggattg tctttacaga ccaaggaatg
    11941 acagaacacc actttatcga aaatgacggc tttgtcgctg aagattagta ctcctagcag
    12001 ggtatggtct tgtcaaaata tcaaaaacaa tttataataa atagataccc tgaaaggaag
    12061 agaatcatga acttagaaga attgaaaaaa cgacagggga agatccgtaa cttctctatt
    12121 atcgcccata ttgaccacgg gaaatcaact ctagcagacc gcattttgga aaaaacagag
    12181 acggtttcaa gtcgtgaaat gcaggcccag cttttggata gcatggatct agagcgggaa
    12241 cgtggaatta ctattaagtt gaatgccatc gagttgaatt acactgcaaa agatggggaa
    12301 acttatattt tccacttgat tgacacacca gggcacgttg actttaccta tgaagtttca
    12361 cgttcgctag ctgcctgtga gggtgctatt ttggtggtcg atgcggctca aggaattgag
    12421 gctcaaactc ttgccaacgt ttatctggct ttggataatg atttggaaat catgcctatc
    12481 attaataaaa ttgacctgcc ggctgcagat ccggagcgcg tgcgtacaga gattgaagat
    12541 gtgattggtt tggatgccag tgaagcagtt ttggcttctg ccaaggctgg tattgggatt
    12601 gaagaaatcc tcgagcaaat tgtagaaaaa gtaccagcac caacgggtga tgtgacggcg
    12661 ccacttaagg ccttgatttt cgactctgtt tacgatgctt accgtggggt tatcctccaa
    12721 gtacgtgtca tggacggagt ggtcaaacct ggtgataaga ttcagctcat gagcaatagt
    12781 aagacctttg atgtggccga agtcggtatt tttacaccaa aagcggttgg tcgtgatttc
    12841 cttgcgactg gtgatgttgg ttacattgcg gcgtctatca agacggttca ggatactcgt
    12901 gtgggtgata ccgttacctt ggcaaccaat cctgcggcag aaccattaca tggttataag
    12961 cagatgaatc ctatggtctt tgcgggtctc tacccaatcg aatcaaacaa gtacaatgac
    13021 ctgcgtgaag cgcttgaaaa attgcaactg aatgatgcta gtcttcagtt tgaaccagaa
    13081 acatctcagg cacttggatt tggtttccgt tgtggatttc ttggacttct ccatatggat
    13141 gttatccagg aacgtttaga gcgtgagttc aatattgatc tcatcatgac agctccgtct
    13201 gttatttaca aagttaattt gaccgacggt gagtctatgg atgtgtctaa cccatctgag
    13261 tttccagacc caactaagat tgcgaccatt gaagagcctt atgtcaaggc gcaaatcatg
    13321 gtaccacagg agttcgtcgg agcagtaatg gagctagctc agcgtaagcg tggggacttt
    13381 gtgactatgg actatattga tgataaccgt gtcaatgtta tctatcaaat tcctcttgct
    13441 gaaattgtct ttgacttctt tgataaactt aagtcttcga cacgtggtta tgcaagcttt
    13501 gactacgaat tgtcagaata tcgcccatct aagctggtga aaatggatat tcttctcaat
    13561 ggagataagg tggatgccct cagctttatc gttcacaagg actttgccta cgaacgtggg
    13621 aaactcatcg ttgataaact caagaaaatc atccctcgcc aacaatttga agttccaatc
    13681 caagcggcta ttggacacaa gattgtcgct cgtactgata tcaaggccct tcgtaagaac
    13741 gtacttgcta aatgttatgg tggtgacgtt tctcgtaagc gtaaactcct tgaaaaacaa
    13801 aaagctggta agaaacgcat gaaatccatc ggatcagttg aagttccgca agaagccttc
    13861 ctcagcgtct tgagtatgga tgaagaataa gttatcagaa atgcctttcc ttgttcacag
    13921 gaaatttata taagaatcaa tagtaaagca ggcttagatg gtctgctttt ttagttttta
    13981 tactcttcga aaatctcttc aaaccacgtc agcgtcgcct tactgtatgt atggttactg
    14041 acttcgtcag tttcatctac aacctcaaaa ctgtgttttg agtaacctgc ggctagcttc
    14101 ctagttt
//
LOCUS       DAVLDI010000055        14038 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLDI010000055 DAVLDI010000000
VERSION     DAVLDI010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14038
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.055"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(33..176)
                     /locus_tag="VXD01_001797"
     CDS             complement(33..176)
                     /locus_tag="VXD01_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV0602145.1"
                     /translation="MAESPNSPLSAISDQVGFSDYKYFAKVFKKHLHISPKELKLLGR
                     IVK"
     gene            complement(275..508)
                     /locus_tag="VXD01_001798"
     CDS             complement(275..508)
                     /locus_tag="VXD01_001798"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEV0602146.1"
                     /translation="MQYGAVDFLSKPIDTKELTECLQKIVLRLQISTSQETPFLEEYQ
                     TLLTSIQQVDTQNQIIQQIISFVHKHYAEHYYC"
     gene            complement(557..784)
                     /locus_tag="VXD01_001799"
     CDS             complement(557..784)
                     /locus_tag="VXD01_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEV0602147.1"
                     /translation="MFKLIIVEDEHLIRKWLEIAVDYSALGIQVVGTASHGQEGMKLI
                     QEKETHICLNRHHNANYGCFYDVQSHSYSFL"
     gene            complement(788..1171)
                     /locus_tag="VXD01_001800"
     CDS             complement(788..1171)
                     /locus_tag="VXD01_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0602148.1"
                     /translation="MIHKIRFEHFSYDIVCPETVDNQPIPKLFLLPLVENAIKHGMQY
                     RIDLHIDIHITLEADSLTFLVKDNAGGLTKQERFAILDSLESPHTQHGIMNSYKQLSN
                     FFSDVQLDLGVNRQGETWVKFVTKD"
     gene            complement(1504..2280)
                     /locus_tag="VXD01_001801"
     CDS             complement(1504..2280)
                     /locus_tag="VXD01_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV0602149.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            2402..3148
                     /locus_tag="VXD01_001802"
     CDS             2402..3148
                     /locus_tag="VXD01_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0602150.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            3161..4141
                     /locus_tag="VXD01_001803"
     CDS             3161..4141
                     /locus_tag="VXD01_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV0602151.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            4336..4656
                     /locus_tag="VXD01_001804"
     CDS             4336..4656
                     /locus_tag="VXD01_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0602152.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            4702..5010
                     /locus_tag="VXD01_001805"
     CDS             4702..5010
                     /locus_tag="VXD01_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0602153.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            5027..6325
                     /locus_tag="VXD01_001806"
     CDS             5027..6325
                     /locus_tag="VXD01_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0602154.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            6476..8914
                     /locus_tag="VXD01_001807"
     CDS             6476..8914
                     /locus_tag="VXD01_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV0602155.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQYILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            8933..9601
                     /locus_tag="VXD01_001808"
     CDS             8933..9601
                     /locus_tag="VXD01_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV0602156.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLVLAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            9619..10707
                     /locus_tag="VXD01_001809"
     CDS             9619..10707
                     /locus_tag="VXD01_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV0602157.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            11162..13663
                     /locus_tag="VXD01_001810"
     CDS             11162..13663
                     /locus_tag="VXD01_001810"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV0602158.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAYLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVTTDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYIDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
BASE COUNT         4528 a         2140 c         2891 g         4479 t
ORIGIN      
        1 agagtaaaat tctctacaaa aagaagaata gcctatttta ctattcttcc gagtaatttc
       61 aattcctttg gggaaatatg gagatgcttt ttaaatactt tggcaaaata tttatagtct
      121 gaaaatccaa cttggtcaga gatagcgctt aaaggggagt tgggagattc agccatctta
      181 tctatagctt gtttcaggcg atattgtaag atatattcat ttagagtcat ctttgataac
      241 cttatataga tagctttcgt tatagtttaa agcttcagca atagtaatgc tctgcatagt
      301 gcttgtggac aaaggagata atttgttgaa tgatttggtt ttgtgtatca acctgttgga
      361 tagaggtgag taaagtttga tattcttcta aaaaaggagt ttcttgagat gtgctaattt
      421 gtaatcgcaa aacaattttt tgaagacatt ctgtcaattc cttggtatca attggcttgg
      481 ataagaaatc aactgctcca tattgcatgg ctttttggca ttttgaaaat cgttataacc
      541 tgataagata actttttcat aagaaagagt acgagtggct ttgaacatca taaaagcatc
      601 cataattggc attgtgatgt ctgttaagac aaatatgagt ttctttttct tggatgagtt
      661 tcattccttc ttgaccgtga ctggcagttc ctacgacttg gatgcctaag gcagagtagt
      721 ctacggcaat ctctagccat tttcggatga ggtgttcatc ttctacaata atgagcttaa
      781 acatgagtta gtctttcgtt acaaatttga cccaagtttc tccttggcga ttgactccta
      841 aatctagctg gacatcagaa aagaaattgc tcaattgttt gtagctgttc atgatgccat
      901 gctgggtatg agggctttct aaagagtcta aaatagcgaa tcgctcttgt ttggtgagtc
      961 ctccagcatt atccttgact aaaaaagtta gagaatctgc ttccaaggta atgtggatat
     1021 caatatgaag atcaatacgg tattgcatcc catgttttat agcattttct actagaggaa
     1081 gcaagaaaag tttagggata ggctgattat cgacagtttc tgggcagaca atatcatagg
     1141 aaaagtgctc gaaacgaatc ttatgaatca taaggtaatc ctctataatc tttaaatcct
     1201 gacaaatggt tgtttctttt tctaaatcgg tgatactgta tcggagaatg cgcgtgaggt
     1261 cacaaaggct gcgatagagc ttctatggag aatttctttt tggagagatt ttttaaagga
     1321 atgagacatc cgctacctca ttggaaggtt tttttgtgat aagtatagca gtttaaaaat
     1381 tctagagcaa ggtaaaatag aaaaggtttg gctaaaattt tttagctaaa ccttttgaaa
     1441 agttaagtat gtattataga tgcttgttat ctgcaaatag ctagagcatt tcaaggaaat
     1501 gaactagaaa taacaattaa tatggtggtt cagaaatacc ttttgataat caataagatc
     1561 ttcaggatga agtgcgttga ttccatccat ttcatatttc cgatttaata aacgatattt
     1621 gttttcacca aattgatgaa aagggagtag ttgaacttgg tcgatattta atgagttaaa
     1681 tagagtagcg aatttttctg catcctctaa actattgtta aaattaggaa taactgggat
     1741 tcttaaaacg atagttttat tttgagaaaa agcataatga atgtttttaa taatcatttg
     1801 attaaaaacc ccagtcactt ttttatgttt tatagaatta taatgtttta ggtctgtgta
     1861 gataaaatcc acatattgaa ttaaatcgat aaatttttca tgatcaacaa aggcagtagt
     1921 ttcaatggca gtgtgtatgt gatgttcttt agctgatttt aagatggctt tagcaaattc
     1981 aaactgagca aatatttcac ctcctgataa agttaaacct ccaccggatt cttcgtaaaa
     2041 ttctttgtct tttaatacct ctgtaataat ttcttctaca gtcttttctt caccgactaa
     2101 ggtgaatttc tctcgttgag catctttcat tttttcaggt ttcattcttt gagattcagg
     2161 attagaacac catggacagc gcagaggaca tccttttaaa aaaacagttg tacgaatacc
     2221 cgggccgtca tgaattgaaa agtgttgaat attaaaaata attcctttag atatttccat
     2281 aagagttcct cctcttcata agtctatcct atcacaaaaa cgaaagaaaa acaattacga
     2341 acgaaagttt aatttgttgt tttttgcttt ttattttggt agaataaaac ggaggtgtaa
     2401 aatgaaaaga ttggaacaaa ttattaaatt agtatcagaa tatgaaaaga tcgacgttaa
     2461 tacattatcg gaaaaattaa atgtatcgaa agtaacgatt agaaaagatt tagataaatt
     2521 agagtcaaaa ggtttattac acagagagca tggatatgct gtattaaata gtggagatga
     2581 cttaaatgta cgtttgtcaa ttaattatga aattaagaga aaaattgttc aggaagcagt
     2641 aaaattggtg tcagataatg aaacaataat gatagaatct ggatcgacct gtgctttact
     2701 tgctgaggaa atttgcaagc aaaaaagaaa tgttacgatt gtaacaaatt cattttttat
     2761 agcaaatttt gtgagagctt atgattcatg tcgtattatt gttcttggtg gagagtttca
     2821 gaaggattca caggttactg tgggaccttt attaaaagaa atgatacaga cttttcatgt
     2881 gcatcaagct tttgttggga cagatggtta cgataaagag atgggcttta caggaaaaga
     2941 tttaatgcgc agtgaggtag ttcaatatat ttcagcagcg tcggataaag tcattgtact
     3001 aactgactca agtaaatttg ataaaagggg tacagtaaga agatttgctt taagtcaagt
     3061 ctatgaagta ataacagacg aaaaactttc taaacaaaat atagctacat tagaaaatgc
     3121 tgggataatg gttaaggtag tttcgtaaga ggttaaatgt atgaatcaag ataggaataa
     3181 actgctctct aaaattgctt atctgtatta tattgaaaac ttaaatcagt cacaaatagc
     3241 agcaaaatta ggaatttata gaacctctat tagtagaatg ttaacagaag caaggaatgc
     3301 aggaattgtt aaaattgaaa tagagaattt tgataccaat atgtttaagt tggaaaatta
     3361 tgtaaaagaa aaatatggtc tggaaagttt agaaattatt ccaaatgaat ttgatgataa
     3421 tccaacaatt ttatctgaaa gaatttctca agttgcagca ggtgtcctta ggaatctaat
     3481 tgatgataat atgaaaattg gcttttcttg ggggaaaagt ttaagtaatt tagtagattt
     3541 aattcacagt aaaagtgtcc gaaatgttca cttctatcct ctagcaggtg gtcctagtca
     3601 catacacgct aaataccatg tgaatacact gatttatgaa atgtctagaa aatttcatgg
     3661 agagtgtaca tttatgaatg caacgattgt gcaagaaaat aaattgttag cagatggtat
     3721 tttgcaatca agatattttg aaaatttgaa aaatagttgg aaagatttag atatagctgt
     3781 agtcggaatt ggtgatttta gcaataaagg aaagcatcaa tggttagaca tgcttacaga
     3841 ggatgacttt aaagaattga ccaaagttaa aactgtagga gaaatttgtt gtcgattttt
     3901 tgattcaaaa ggtaaagaag tctatgaaaa cttacaggaa agaacgatag caatctcttt
     3961 ggaagattta aaaaatattc ctcaaagttt agctgttgct tacggtgata cgaaagtatc
     4021 ttcgattctt tctgtcttgc gtgctaattt agtaaatcat ttgattacag acaaaaatac
     4081 aattttaaaa gttttggaag aagatgggga tttgactttt agagagattc taggtgagtg
     4141 aaaatgatag actgattcag tttatcgttt ttctttttag ttgattgcac atttgtgctt
     4201 atataaacaa aaatagttta tctgttgttt ttggattgac aactttatta tgtagttgta
     4261 ttctatagtt acaaaagaaa attttaaaat ttcaaatgaa aaaagctttt tacatagtga
     4321 aatgaggagg aatttatgga aattattgtt ccagatcaaa ttatcatggg tttaatttta
     4381 tatgctggtg atgcgaaaca acatatttat aaagcgttag attacataaa aaatggtaca
     4441 tgtgaacggt gtgaagaaga aatccagtta gctgatgcag ccttattaga agctcataat
     4501 ctacaaacaa aattcttggc acaggaagcg tctggtacaa agacagaaat tacagctctc
     4561 tttgttcatt cacaagatca tctcatgact agtatgacgg agattaattt aatcaaagaa
     4621 attattagtt tgagaaaaga acttcataaa aaataatact agagtattat cattgttatt
     4681 aacatagagg aggaaaacat aatggtgaag attggtttgt tttgtgcagc aggtttttct
     4741 actggtatgc ttgtaaataa tatgaaaatt gcagcgcaat ctagtggagt tgaggcagaa
     4801 atagaggcgt tttctcagtc taaattagcg gattatgcgc caaatataga tgttgcacta
     4861 ttgggtccac aagttgctta tacattagat aaatcaaaag aaatttgtga taagtgtgat
     4921 gttccgatag ctgttattcc gatgatggac tatggtatgt tagatgggaa aaaagtatta
     4981 gatttggccc tatctttgat tagtgggtaa gaaaaggaga tttattatgt caaagatgga
     5041 tgttcagaaa atcattgcac cgatgatgaa gtttgtgaat atgcgtggca ttatagctct
     5101 aaaagatggg atgttagcaa ttttgccatt gacagtagtt ggcagtttgt tcttgattat
     5161 gggacaattg ccgttcgaag gattaaataa gagcattgct agtgtttttg gagctaattg
     5221 gacagagccg tttatgcaag tatattcagg aacttttgct attatgggtc taatttcttg
     5281 tttttcaatt gcctattctt atgctaagaa tagcggagta gaggctttac cagctggagt
     5341 tctatctgta tctgcattct ttattttgct aagatcatct tatatcccta aacaaggtga
     5401 ggcgattggg gacgctatta gtaaagtttg gtttggaggc caaggaatta tcggtgctat
     5461 cattataggt ttggtagtag gaagtattta taccttcttt ataaagagaa aaattgttat
     5521 taagatgcca gaacaagttc cacaagctat tgccaaacag tttgaagcaa tgattccagc
     5581 atttgtaatt ttcttatctt ctatgattgt atatatttta gcgaagtcat tgactaatgg
     5641 cggaacattc atagaaatga tttattctgc tattcaagtt ccgttgcaag gtttaactgg
     5701 atctttgtat ggtgctattg gaattgcatt ctttatatca tttttgtggt ggtttggtgt
     5761 tcatgggcaa tcggtagtaa atggagtagt gacagctctg cttttatcta atcttgatgc
     5821 taataaagct atgttagcct ctggtaatct atcattagaa aatggtgcac atattgttac
     5881 tcaacaattt ttagattcat ttttaattct atcaggttca gggattacgt ttggtcttgt
     5941 agttgccatg ctttttgcag caaaatcaaa acaataccaa gccttaggaa aagttgcagc
     6001 ttttccagca atatttaacg taaatgagcc agttgtattt ggatttccga ttgtcatgaa
     6061 tccagttatg tttgtacctt tcattcttgt tcctgtactt gcagctgtga tagtatatgg
     6121 agctattgca acaggtttca tgcagccatt ctcaggggta acattgcctt ggagtacacc
     6181 agctattcta tcaggatttt tggtgggtgg atggcaaggt gttgtgactc agttattagt
     6241 attggtgata tctacagtgg tttactttcc attctttaag atacaagatc gtttagctta
     6301 ccaaaatgaa atcaaacaat cttagaggta tttgtgtgtt actgttaaac tcacacattt
     6361 gtgctaaaaa ttagagagtt aaaatttttc tagttaaaag cttgaaaatt tctataaaaa
     6421 tcggtattat attttcgaaa gaaataaaaa tattttcgaa agaaaggtgc ttacgatggt
     6481 aaatacagaa gtagcaagaa caacaatcaa aacagaatat tttggcagcc ttactgaaag
     6541 gatgaacaaa tatcgagaag atgttttaaa taaaaaacct tatattgatg ctgagagagc
     6601 agttctagca acacgcgcct atgaacgata caaggaacaa cctaatgtcc taaaacgtgc
     6661 atatatgctg aaagaaattt tggaaaatat gtctatctat attgaagaag aatctatgat
     6721 tgcgggaaat caagcttctt ccaataaaga tgctcctatt tttccggaat atacgctaga
     6781 atttgttctc aatgagttgg atctttttga aaagcgtgat ggagatgttt tctatattac
     6841 agaagaaaca aaagaacaac ttagaagtat tgctccgttt tgggaaaata ataatttacg
     6901 tgctagagct ggtgccttat tacctgaaga agtgtcagtt tatatggaaa caggattctt
     6961 cggtatggaa ggtaagatga attctggaga tgctcactta gcagttaact atcagaaact
     7021 tttgcaattt ggtttaagag gttttgaaga gcgggctcgt aaagcaaaag tagctctaga
     7081 tttaacagat ccagcaagta ttgataaata tcatttttac gactctatat ttatcgtaat
     7141 cgatgctatt aaagtatatg caaagcgctt tgttgctctt gctaaaagtt tagccgaaaa
     7201 tgcaaatcct aaacgtaaga aagaattact tgagattgca gatatttgct ctagagtccc
     7261 atatgaaccg gcaactactt ttgcagaagc tattcaatca gtttggttta ttcaatatat
     7321 tttacaaatt gaatctaatg gccactctct ttcatatggc cgttttgatc aatatatgta
     7381 tccatatatg aaggctgatt tagaaagtgg taaagaaaca gaagatagca ttgttgaacg
     7441 tctgacaaat ctttggatta agacaattac aattaataag gttcgcagtc aatcacatac
     7501 attttcttca gcaggaagtc ctttatatca aaatgttaca attggtggac agactcgaga
     7561 taagaaggat gctgttaacc cattatctta tttggtatta aaatcagttg cacaaaccca
     7621 tctaccgcaa cctaatctaa ctgtacgtta ccatgcaggt ttagatgctc gtttcatgaa
     7681 tgagtgtatt gaagtgatga aacttggttt tggtatgcct gcatttaata atgatgagat
     7741 tattattcct tcttttattg caaaaggagt attggaagat gatgcttatg attacagtgc
     7801 cattggatgt gttgaaacgg cagttccagg gaaatggggc tatcgttgca caggtatgag
     7861 ttatatgaac ttccctaagg ttctacttat cacgatgaat gatggaattg atccggcttc
     7921 gggtaaacgg tttgcaccaa gctttggtca ttttaaggat atgaagaact tttctgaatt
     7981 agaaaatgct tgggataaaa cactaagata tttgacacga atgagtgtta ttgttgaaaa
     8041 ttctattgat ttatcattgg aacgagaagt tcctgatatt ctatgttcag cattgactga
     8101 tgattgtatt ggtcgtggaa aacaccttaa agaaggtgga gcagtatatg attatatatc
     8161 aggattgcaa gttggaattg caaatttgtc ggattcatta gctgcaatta aaaaattggt
     8221 gtttgaggaa gaacgtataa gcccaagtca gctttggcat gcactggaaa cagattatgc
     8281 cggagaagaa ggtaaggtca ttcaagaaat gttgattcat gatgcaccta agtatggtaa
     8341 tgatgatgat tatgctgaca aattggttac tgctgcttat gacatttatg ttgatgaaat
     8401 tgctaaatat cctaatacac gttatggaag aggtccaatt ggaggaattc gttattcagg
     8461 aacatcttct atctcagcca acgtagggca gggacgtgga acattagcaa ctccagatgg
     8521 acgcaacgcg ggtacaccgt tagcagaggg ttgttcacca tcacataata tggatcaaca
     8581 cggccctaca tctgttttaa aatctgtttc aaaattacca acagatgaaa tcgtaggtgg
     8641 ggttctctta aatcagaaag taaatcctca aacgttagcc aaagaagaag ataaattaaa
     8701 actaattgct ttgttacgaa cattctttaa tcgtttacat gggtaccata ttcaatacaa
     8761 tgttgtttcc agagagacgt tgattgacgc tcagaaacat cctgaaaaac acagagactt
     8821 aattgttcgt gttgcaggat actctgcatt cttcaatgtt ctttctaagg caacccaaga
     8881 tgacattata ggacgtactg agcatacttt gtaaaataaa gaggttcttt ttatggaatt
     8941 tatgcttgac acattaaatt tagatgagat taaaaagtgg tctgaaattt tgccgctagc
     9001 tggggtaact tcaaatccca ctattgcaaa aagagagggt tctattaatt tttttgaacg
     9061 aatcaaagat gtaagagaat tgattggctc tacaccctct attcatgttc aggtgatttc
     9121 tcaagatttt gaaggcatct taaaggatgc tcatgaaatt cgaagacaag caggagatga
     9181 tatatttatc aaagtacctg ttactccagc tggattacgt gcaataaagg tgctaaaaaa
     9241 agagggctac catatcactg caacagctat ttatacagtt attcagggat tattagctat
     9301 cgaagcagga gcggattacc tagctccata ttataataga atggaaaatc tgaacattga
     9361 ttcaaattct gtcattcgtc aattagttct tgctattgat agacagaact ctcctagtaa
     9421 gattttggct gcatccttta aaaatgtagc acaagtaaat aatgctttag ctgcaggtgc
     9481 gcatgctgtt acagcaggag cggatgtttt tgaatcagct ttcgccatgc catctatcca
     9541 aaaggcggtt gatgattttt ctgacgattg gtttgttatt caaaatagtc gttccattta
     9601 gatagagagg aaatacatat gagaattttt gctagtcctt ctagatatat tcagggggaa
     9661 aatgccttgt ttgaaaatgc caaatcaatt ttggatttgg gaaattgccc tattctatta
     9721 tgcgatcagt tggtttatga tattgttgga aaacgatttg aagattacct acataggtat
     9781 ggtttccata ttgttctggc gctatttaat ggtgaagctt ctgacaatga aatcaatcga
     9841 gttgttgcct tggctgagaa agaaaattgt gatagtatta tcggtcttgg tgggggaaag
     9901 acgattgata gcgcaaaagc tattgcagat ttgattgaaa agcctgttat tattgctcca
     9961 acaattgcat cgaccgacgc acctgtatct gctttatctg ttatttatac agatgaaggt
    10021 gcatttgatc attatctatt ttattctaaa aatccagatt tagttttggt tgatacaaaa
    10081 gttatttcac aagcccctaa gcgtttatta gcgtctggta ttgcagatgg tttagcaact
    10141 tgggttgagg cgcgtgcggt tatgcaggca aatggaaaaa ctatgttggg acaacagcaa
    10201 acattggctg gagttgcaat tgcgaagaaa tgtgaagaaa cgctgtttgc agatggttta
    10261 caggctatgg cagcttgtga agctaaagtg gtgacaccag cattagaaaa tattgttgaa
    10321 gctaatactt tattgagtgg tctaggtttt gaaagtggag gattagctgc ggcgcatgca
    10381 attcataatg gttttactgc attgacaggt gacattcatc atttaacaca tggtgaaaaa
    10441 gtagcttatg gaactttagt acaactatta ttggaaaata gacctaaaga agaacttgat
    10501 aagtatattg agttttacaa aaaaattggt atgccaacaa ctctaaaaga aatgcatttg
    10561 gatcaagttg gatatgatga tttaataaaa gttggtaaac aagcaactat ggagggtgag
    10621 acaattcatc agatgccgtt taagatttcg ccttcagatg ttgctcaagc tattatcgct
    10681 gtagatgcct atgtaaattc aaaataaaca ataaggacta ctgttttcca aatggtagtc
    10741 ttttattgat ccctgtattg aattctatag aagattgaaa taggatgaga acaaatcgat
    10801 tgggaaagta aaattaattt ctataaatgt tttagcaatt gtttcgtact atttcagatt
    10861 cagtctacta tacgttcttc ataaatcaaa aagcgacata ggtagtcggc tatttattgt
    10921 gaatacatta attagcattc cagttttatc ttcggtctaa aataagtatt ttgtgctata
    10981 cgagataagc ttcttgactt actccttgat ttactgcata acaatgggat aaaaagtggg
    11041 agatagagca attcatagtc atcaaaatta atgagataca gtatacagtt ttttctttaa
    11101 acacatttca aattccctca aaaatggtat aatagtaaca tcacaaaatt ggagagagac
    11161 catgagtttt tataatcata aagaaattga gcctaagtgg cagggctact gggcagaaca
    11221 tcatacattt aagacaggaa cagatgcatc aaaacctaag ttttatgcgc ttgatatgtt
    11281 cccttatccg tctggagctg gtctgcacgt aggacaccca gaaggttata ctgcaaccga
    11341 tatcctcagt cgttacaaac gtgcgcaagg ctacaatgtc cttcacccaa tgggttggga
    11401 tgcttttggt ttgcctgcag agcaatacgc tatggatact ggtaatgacc cagcagaatt
    11461 tacagcggaa aacattgcca acttcaaacg tcagatcaat gcgcttggat tttcttatga
    11521 ctgggatcgt gaagtcaaca caacagatcc aaactactac aagtggactc aatggatttt
    11581 caccaagctt tacgaaaaag gcttggccta tgaagctgaa gtgccagtaa actgggttga
    11641 ggaattggga actgccattg ccaatgaaga agtgcttcct gacggaactt ctgagcgtgg
    11701 aggctatcca gttgtccgca aaccaatgcg ccaatggatg ctcaaaatca cggcttacgc
    11761 agagcgcttg ctcaatgact tagatgaact agattggtca gagtctatca aggatatgca
    11821 acgcaactgg attggtaaat caactggtgc caatgtaact ttcaaagtaa aaggaacaga
    11881 caaggaattt acagtcttta ctactcgtcc ggacacactt ttcggtgcga ctttcactgt
    11941 cttggctcct gaacatgaat tagtagacgc tatcacaagt tcagagcaag cagaagctgt
    12001 agcagactat aaacaccaag ccagccttaa gtctgacttg gttcgtacag accttgctaa
    12061 ggaaaaaact ggtgtttgga ctggtgctta tgccatcaac cctgtcaatg gtaaggaaat
    12121 gccaatctgg attgcggact atgttcttgc tagttatgga acaggtgcgg ttatggctgt
    12181 gcctgcccac gaccaacgtg actgggaatt tgccaaacaa tttgaccttc caatcgtcga
    12241 agtacttgaa ggtggaaatg tcgaagaagc tgcctacaca gaggatggcc tgcatgtcaa
    12301 ttcagacttc ctagatggat tgaacaaaga agacgctatt gccaagattg tggcttactt
    12361 ggaagaaaaa ggctgtggtc aggagaaggt tacctaccgt ctccgcgact ggctctttag
    12421 ccgtcaacgt tactggggtg aaccaattcc aattattcat tgggaagatg gaacttcaac
    12481 agctgttcct gaaactgaat tgccgcttgt cttgcctgtc accaaggaca tccgtccttc
    12541 aggtaccggt gaaagtccac tagctaactt gacagactgg cttgaagtga ctcgtgaaga
    12601 tggtgtcaaa ggtcgtcgtg aaactaacac catgccacaa tgggctggtt caagctggta
    12661 ctaccttcgc tatattgacc cgcacaatac tgagaaattg gctgatgagg acctcctcaa
    12721 acaatggttg ccagtagata tctacgtggg tggtgcggaa catgctgtac ttcacttgct
    12781 ttatgctcgt ttctggcata aattcctcta tgacctcggt gttgttccga ctaaggaacc
    12841 attccaaaaa ctctttaacc aagggatgat tttgggaaca agctaccgtg accaccgtgg
    12901 tgctcttgtg acaaccgaca aggttgaaaa acgtgatggt tccttcttcc atgtagaaac
    12961 aggggaagag ttggagcaag cgccagccaa gatgtctaaa tcgctcaaga acgttgttaa
    13021 cccagacgat gtggtggaac aatacggtgc cgataccctt cgtgtttatg aaatgtttat
    13081 gggaccactc gatgcttcga ttgcttggtc agaagaaggt ttggaaggaa gccgtaagtt
    13141 ccttgaccga gtttaccgtt tgattacaag taaagaaatc cttgcggaaa acaatggtgc
    13201 tcttgacaag gcttacaacg aaacagtcaa agctgttact gagcaaattg agtctctcaa
    13261 attcaacaca gctattgccc aacttatggt ctttgtcaat gctgctaaca aggaagataa
    13321 gctttatatt gactatgcca aaggctttat tcaattgatt gcaccatttg cacctcactt
    13381 ggcagaagaa ctctggcaaa cagtcgcaga aacaggtgag tcaatctctt atgtagcttg
    13441 gccaacttgg gacgaaagca aattggttga agatgaaatt gaaattgtcg tccaaatcaa
    13501 aggaaaagtt cgtgccaaac tcatggttgc taaagatcta tcacgtgaag aattacaaga
    13561 aatcgcttta gctgatgaaa aagtcaaagc agaaattgac ggtaaggaaa tcgtgaaagt
    13621 aattgcggta ccgaataaac tcgttaatat cgtcgttaaa taacgagttt attagctcta
    13681 tctgccacct tcaatagtcc actggactat tgaagccaac taaattagtt aacattgttg
    13741 tgaaataaaa agaagtaact ctagagtatg aactttagag ttacttttag aataggtcag
    13801 aatgaataga ttagtgaacg atagcaggaa gtgtgaaatt ttattattta agatttctat
    13861 tattgtagtg tcagttatag tattagtaat gtcaatagtg ggtgcatatt attttaaaaa
    13921 ttgtctttgg gacaaggaaa gtttaaattt gatactcact ttagacactc tctttgcagt
    13981 ttttattact ttctttagtt tttcaaatga taaatcaagc aatatttttg gaatatct
//
LOCUS       DAVLDI010000056        13950 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLDI010000056 DAVLDI010000000
VERSION     DAVLDI010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13950
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.056"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            32..6055
                     /locus_tag="VXD01_001811"
     CDS             32..6055
                     /locus_tag="VXD01_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0602159.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     EPAVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQGAENPVQPAEESTTNSEKVSPDTSSENTGEVSNKPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEPSNGN
                     STEDVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLELRNVSDLELYSLSNGTYK
                     QHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKVEKLQQEI
                     ESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNLSGTYHLGASLNANEVELSTDD
                     KSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFENLSGATVEKLSLKNVAISGKNDIGSL
                     ANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESSFKGRIVNTYETTDSYNI
                     GGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLVDRDAQIQDSYAEGDINN
                     VKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGNAITGYHYTGMKVANTFS
                     SKANRVFNVTLEKNEVVSKESFEERGTMLDASQIASKKAEINLITPPIVEPLSTSGKK
                     DSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVKENSILYQKELLSAVMMK
                     DDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQADFANLAEYSIGDSGLLYTPNQF
                     LYHQDSIINQVLPELNRVNYQSDAVRNTLGISPEVKLTELYLEEQFTKTKEHLAENLK
                     KLLSSDAGLVTDNEVMTGYIIDKIKRNKEALLLGMSYLERWYNFSYGQVNVKDLVMYH
                     PDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLASHHGTTDLFSTLENYRKV
                     FLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYSIGVYDRITSATWKYRNM
                     VLPLLTLPERSVFVISTISSLGFDAYDRYRNKEHQANGDLNSFVEKSAHETAERQRDH
                     YDYWYRILDEKGREKLYRNILLYDAYKFGTNHTEGKATEVADFDSPNPAMKHFFGPVG
                     NKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHNSDQDIYLGGYGRRSGLGP
                     EFFAKGLLQAPDQPSDATITINSILKHSKSDSKEGERLQVLDPTTRFKDATDLQKYVH
                     NMFDVVYMLEYLEGKSIVKKLNVYQKIEALRKIENQYLTDPADGNDVYATNVVKNLTE
                     DEAKKLTSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAPIFSALSGEKGTPGDLMG
                     RRIAFELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGKERGLVTDELVLKKVFDG
                     KYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPRYGTKTINNVDELQKLMDEAVL
                     QDAKERNYYYWNNYNPETDSAVHKLKRAIFKAYLDQTNDFRRSIFENKK"
     gene            6099..11423
                     /locus_tag="VXD01_001812"
     CDS             6099..11423
                     /locus_tag="VXD01_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV0602160.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGTSTYHYLDYS
                     TLTQTERVQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVDYLELDDR
                     TVSPVEQPKVVTDKGEPEVQPALPEAVVTGKGKTEVQPTLPEAVVTEKGEPEVQPVLP
                     EAVVAEKGEPEVQPALPEAVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPV
                     GTTGVDENRNLIEPPVNDIPEYTEPISTVSEVASEREELPSLHTDIRTETIPKTTIEE
                     SDPSKFIGDNSVKQVGEDGERQIVTSYEELHGKKISESVETVTILKEMKPEIIVKGTK
                     ERPKEKTAPVLTLTKVTEDAMNRSANLNYELDNKDNAEISSIVAEIKDGDTVVKRVDL
                     SKEKLTDAVQNLDLFKDYKIATTMIYDRGQGSETSKLDERPLRLELKKVEIKNIASTN
                     LVKVNDDGTETPSDFMNEKPSEEDVKKMYLKITSRDNKVTRLTVDSIEEVTEEGQKLY
                     KITAEAQDLIQHTDPTKVRNKYVYYIEKPHPKEDNVYYNFKDLVDAMNTDKNGTFKLG
                     ADLNATGVPTPKKWYVDGDFRGTLKSVEGKHYTIHNTERPLFQNIIGGTVTKVNLGNV
                     NINMPWADRIAPIADTIKGGAKIEDVKVTGNVLGRNWVSGFIDKIDNQGTLRNVAFIG
                     NVTSVGDGGQFLTGIVGENWKGLVERAYVDANLIGKKAKAAGIAYWTQNSGDNHKVGV
                     EGAVKKGIVKGTIQVESPVEVGGAVGRLSHHGYIGEVVSMMKVKKGEIFYGSSDMNDD
                     PYWVANNVRGNYVVNGVSEGTISYARAKEHHRIKPISQSEADTKIMMLGITAQDFAIN
                     EPVVNRLNRLTRKEDEYKSTQDYKVDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSN
                     LAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGTKEEMDVTKNADSKVKQVREYTIA
                     GQNVVYTPNMVEKDRNQLIQDIKDKLASVQLISPEVRALMDARKKPEENTDERKNGYI
                     KDLYLEESFAETKANLDKLVKSLVENADHQLNSDEAAMKALVKKVDENKAKIMMALTY
                     LNRYYDIKYGDMTIKNLMMFKPDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMI
                     GGTIGKSELHGFLDYNMRLFTNDTDLNDWFIHAAKNVYVSEPQTTNPDFVNKRHRAFD
                     GLNNGVHNRMILPLLTLKNAHMFLISTYNTMAYSSFEKYGKYTEEARNEFKKEIDKVA
                     HAQQTYLDFWSRLALPSVRDQLLKSENRVPTPVWDNQNYSGIKGINRMGYDEKKVPIA
                     PIRELYGPTWKFHNTNWNMGAMASIFPNPNNNDQVYFMGTNMISPFGISAFTHETTHV
                     NDRMLYFGGHRHRQGTDVEAYAQGMLQTPSSIGHQGEYGALGLNMAYHRENDGDQWYN
                     YDPDKLQTREDIDRYMKNYNEALMMLDHVEADAVLPQLNGDNSKWFKKIDREIRRNLG
                     DGLNNLVAPHQWDNVRDLNQEESSKKLSSINDLIDNNFMTKHGNPGNGRYRPEDFRPN
                     SAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYDKGFTSYVSSKYQGEADK
                     QNQGRLGDDFIIKKVSNNQFSNLEDWKKYWYHDVKSRAEKGFTEITIDGQTIHNYNEL
                     KDLFDKAVTEDLKKAGNYSNTENLKSKVFKALLKNTDGFFNPLFKKDI"
     gene            11590..12936
                     /locus_tag="VXD01_001813"
     CDS             11590..12936
                     /locus_tag="VXD01_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEV0602161.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFFKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLNLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
     gene            complement(13099..>13950)
                     /locus_tag="VXD01_001814"
     CDS             complement(13099..>13950)
                     /locus_tag="VXD01_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0602162.1"
                     /translation="ILIIHDTDKVPVFLTKDYKPKKDTALPKGLIYARNGSINTPKDS
                     SAPFELINELFQKFNHTDLNIKEQYFHVLKDYKNWFFIENEDGRFFIYNPNPDFYIKL
                     NDDDANRFKTMSYSLNQYQTNIDWQLVQLRYRHLTIDECMAMYLDQGNCLVPSPEVES
                     FKIDYQETIYYHCLYKNTLKYQLLKVFSSIPGLEKYPLTRFKNSIVIYDTKLELKKTH
                     NLINSKFSSKDIVNQLEVTEKDFDFYYKKARHKNPDYSIQENQVNLTELNLVRLLKPQ
                     IIHTSLN"
BASE COUNT         4925 a         2334 c         2798 g         3893 t
ORIGIN      
        1 acatatataa attttatttc aaggaggaat aatggaaaag tattttggtg aaaaacaaga
       61 gcgtttttca tttagaaaat tatcagtagg acttgtatct gcaacgattt caagtttatt
      121 ttttatgtct gtattagcta gttcatctgt ggatgctcaa gaaactgcgg gagttcacta
      181 taaatatgtg gcagattcag agctatcatc agaagaaaag aagcagcttg tctatgatat
      241 tccgacatac gtggagaatg atgatgaaac ttattatctt gtttataagt taaattctca
      301 aaatcaactg gcggaattac caaatactgg aagcaagaat gagaggcaag ccctagttgc
      361 tggtgctagc ttagctgctc tgggaatttt aatttttgct gtttccaaga aaaaggttaa
      421 gaataaaacg gtattacatt tagtattggt tgcgggaata ggaaatggtg tcttagtttc
      481 agtccatgct ttagaaaatc atcttttgct aaattacaat acggactatg aattgacctc
      541 tggagaaaaa ttacctcttc ctaaagagat ttcaggttac acttatattg gatatatcaa
      601 agagggaaaa acgacttctg attttgaagt aagtaatcaa gaaaaatcag cagccactcc
      661 tacaaaacaa caaaaggtgg attataatgt tacaccaaat tttgtagacc atccatcaac
      721 agtacaagct attcaggaac aaacacctgt ttcttcaact aagccgacag aagttcaagt
      781 agttgaaaaa cctttctcta ctgaattaat caatccaaga aaagaagaga aacaatcttc
      841 agattctcaa gaacaattag ccgaacataa gaatctagaa acgaagaaag aggagaagat
      901 ttctccaaaa gaaaagactg gggtaaatac attaaatcca caggatgaag ttttatcagg
      961 tcaattgaac aaacctgaac tcttatatcg tgaggaaact atagagacaa aaatagattt
     1021 tcaagaagaa attcaagaaa atcctgattt agctgaagga actgtaagag taaaacaaga
     1081 aggtaaatta ggtaagaaag ttgaaatcgt cagaatattc tctgtaaaca aggaagaagt
     1141 ttcgcgagaa attgtttcaa cttcaacgac tgcgcctagt ccaagaatag tcgaaaaagg
     1201 tactaaaaaa actcaagtta taaaggaaca acctgagact ggtgtagaac ataaggacgt
     1261 acagtctgga gctattgttg aacccgcaat tcagcctgag ttgcccgaag ctgtagtaag
     1321 tgacaaaggc gaaccagaag ttcaacctac attacccgaa gcagttgtga ccgacaaagg
     1381 tgagcccgct gtccaacctg aattacccga agcagttgta agtgataaag gtgaaccaga
     1441 gcaggtagca ccattgccag aatataaggg gaatattgag caagtaaaac ctgaaactcc
     1501 ggttgagaag accaaagaac agggtccaga aaaaacggaa gaagttccag taaaaccaac
     1561 agaagaaaca ccagtaaatc caaatgaagg tactacagaa ggaacctcaa ttcaaggagc
     1621 agaaaatcca gttcaacctg cagaagaatc aacaacgaat tcagagaaag tatcaccaga
     1681 tacatctagc gaaaatactg gggaagtatc caataaacct agtgattcga caacctcagt
     1741 tggagaatca aataaaccag aacataatga ctctaaaaat gaaaattcag aaaaaactgt
     1801 agaagaagtt ccggtaaatc caaatgaagg cacagtagaa gggacctcaa atcaagaaac
     1861 agaaaaacca gttcaacctg cagaagaaac acaaacaaac tctgggaaaa tagctaacga
     1921 aaatactgga gaagtatcca ataaacctag tgattcaaaa ccaccagttg aagaatcaaa
     1981 tcaaccagaa aaaaacggaa ctgcaacaaa accagaaaat tcaggtaata caacatcaga
     2041 gaatggacaa acagaaccag aaccatcaaa cggaaattca actgaggatg tttcaaccaa
     2101 atcaaacaca tccaattcaa atggaaacga agaaattaaa caagaaaatg aactagaccc
     2161 cgataaaaag gtagaagatc cagagaaaac acttgaatta agaaatgttt ccgacctaga
     2221 gttatacagt ttgtcaaatg gtacttataa acaacacatt tcgttagagc aagttccaag
     2281 caatccaaat agctactttg ttaaagtgaa atcttcttca ttcaaagatg tatacctacc
     2341 agtagcatca atatcagagg aaagaaaaaa tgataaaatc ctttataaaa tcacagcaaa
     2401 agtagagaag cttcagcagg agatagaaag cagatataaa gataatttta ccttctatct
     2461 agctaagaag ggaacagaag aaacaacaaa ctttacttcc tttagtaatc tggtcaaagc
     2521 tataaaccaa aatctctctg gaacctatca tttaggagct agcctgaatg ctaacgaagt
     2581 ggagcttagt actgatgata aatcctatat caagggaacc tttactggtc agttgattgg
     2641 tgaaaaagat ggtaagcatt atgctattta caacttgaaa aagcctcttt ttgaaaactt
     2701 gagtggtgct acagtagaaa aactgagtct aaaaaatgtt gctatttcag ggaaaaatga
     2761 tattggttca ctggcaaatg aagctacgaa tggcacaaag attaaacaag ttcatgttga
     2821 tggtgttctt gctggagaac gtggtgtcgg tggtttgttg gctaaggcag accaatcaag
     2881 catcgcagag agcagtttca agggaagaat tgtcaatacc tatgaaacga ctgattccta
     2941 caatattggc ggtctggtcg gtcatttaac aggaaaaaat gcgtctattg ctaaatccaa
     3001 agcgacagta accatttcgt caaacaccaa taggtcagat cagactgtcg gtggtcttgc
     3061 aggtctagta gaccgagatg cacagatcca agatagctat gctgaaggtg atatcaacaa
     3121 tgtcaagcac tttggtagag tcgctggagt ggcaggcaat ttgtgggatc gaacttctgg
     3181 tgatgttagg catgctggaa gtttgaccaa tgttctcagc gatgttaatg taacaaacgg
     3241 aaatgccatc actggatacc actatacagg aatgaaggta gctaatacat ttagtagtaa
     3301 ggctaataga gttttcaatg tcactttaga gaagaatgag gtcgtcagca aagaatcctt
     3361 cgaggaaaga ggaacaatgc tagatgcttc tcaaattgca agcaaaaaag cagaaatcaa
     3421 tcttatcact ccaccaatag tggaacccct ctcaacaagc ggtaagaaag acagtgattt
     3481 ttctaagata gcccattatc aagccaaccg tgctttggtt tataagaaca ttgaaaaatt
     3541 gttacctttc tataacaagg cgaccatcgt gaaatacgga aacctggtta aggagaacag
     3601 tatcttatat caaaaagaac tcttgtctgc agttatgatg aaggatgacc aagtaatcac
     3661 agatattatt tccaacaaac agactgcaaa caaactcttg cttcactaca aggaccattc
     3721 atctgaaaag tttgatctca ggtaccaggc tgattttgcc aatttggcag aatatagcat
     3781 tggagatagt gggcttctct atacgccaaa tcaattcttg tatcatcaag attctattat
     3841 taaccaagtg ctgcctgaat tgaatcgagt aaattatcaa tcagatgctg ttagaaatac
     3901 acttggaatt tcaccagaag tgaagctaac ggagttatat cttgaagaac aatttaccaa
     3961 aacgaaagag catctagcag agaacttgaa aaaactttta tcatctgatg caggtttagt
     4021 aacagacaat gaagttatga caggatatat aatagataaa attaaacgga ataaggaagc
     4081 cttacttctt ggaatgagtt atttagaacg ttggtataac tttagctatg gtcaagtgaa
     4141 tgtcaaagac ctagttatgt atcatccgga cttctttggt aaaggaaata cttcaccatt
     4201 agatactctg attgagttag gtaaatctgg ctttaacaat cttcttgcta aaaacaatgt
     4261 cgatacttat gctatcagcc ttgccagcca tcatggaacg acagatttgt ttagcacgtt
     4321 ggaaaattac cgaaaagtct ttctaccaga taaaaccaat aatgactggt ttaaatcaca
     4381 gactaaggct tacattgtcg aagaaaaatc caatatcgaa gaggtgaaaa cgaagcaagg
     4441 actagttggc actaagtatt ctattggtgt ctatgaccgt atcactagtg ccacatggaa
     4501 ataccgtaat atggtactac ctctacttac cttgccagaa agatccgtat ttgtcatttc
     4561 aaccatatct agtctaggtt ttgatgctta tgatcgctat cgtaataaag aacatcaagc
     4621 aaatggtgat cttaatagct ttgttgaaaa gagtgctcac gaaacagcag agcgtcaacg
     4681 agatcactat gattattggt atcgtattct agatgaaaaa gggcgtgaaa agctttatcg
     4741 aaatatcttg ctttatgatg cctataaatt tggaactaat catactgaag gaaaggctac
     4801 agaagtagca gattttgata gtccaaatcc tgcaatgaaa catttctttg gacctgttgg
     4861 aaataaggtt ggacataatg gacatggtgc ttatgctaca ggggatgcag tatattatat
     4921 ggggtatcgc atgctagata aggatggagc tattacgtat actcatgaga tgacgcataa
     4981 ttcagatcaa gatatttatc ttggtggtta tggaagaaga agtggacttg gacctgagtt
     5041 ctttgctaaa ggcttactac aagcaccaga ccaaccaagt gatgcaacga ttactatcaa
     5101 ttctatattg aaacattcaa aatctgatag taaagaagga gaacgattac aagtacttga
     5161 tccaactacg agatttaaag acgcaacaga tcttcaaaaa tacgtccaca atatgtttga
     5221 tgttgtttat atgttggaat atctcgaagg taaatctatt gttaagaaat taaatgtata
     5281 tcagaaaata gaagctctca gaaaaatcga gaaccaatat ctaacagatc ctgctgatgg
     5341 aaatgatgtt tatgctacta atgttgtgaa aaatttgact gaagatgaag ctaaaaaatt
     5401 gacgagcttt gatagtttga ttgacaataa cattctttcg gctcgtgagt ataaggctgg
     5461 cacttatgag agaaatggct actttactat aaaactcttt gcaccaatct tttcagcatt
     5521 gagcggtgag aaaggaactc caggtgacct tatgggacga aggatagctt ttgaacttct
     5581 agctgctaaa ggatttaaag atggtatggt accatatatt tccaaccaat acgaagaaga
     5641 tgctaaacaa caagggcaaa ctatcaatct ttatggtaaa gaacggggct tggtgaccga
     5701 tgagcttgtt ttgaaaaagg tatttgatgg taagtataaa acttgggcag aatttaagac
     5761 agctatgtac caagaacggg tggatcagtt tggaaacttg aagcaggtga cctttaaaga
     5821 tccgacaaaa ccatggccaa gatatggcac aaagactatc aataatgtgg atgaattgca
     5881 gaaactaatg gatgaagctg ttttgcagga tgcaaaagaa cgtaattatt attattggaa
     5941 taactataat ccagaaacgg acagtgccgt ccataagttg aagagagcaa tctttaaagc
     6001 ctatcttgac caaacaaatg attttagaag atcaattttt gagaataaaa aatagtgttt
     6061 actattagga aataaaaagt gaatgtggag gattagaatt gtcattatta aaaaaagata
     6121 aattttccat tcggaaaata aagggtattg ttggttcggt attcttgggg agtcttttat
     6181 ttgcaccgtc agttgttggt acatcgactt atcattactt agattatagt actttgacac
     6241 aaactgaacg tgttcaactc aaacaaggta gacctgatga atcaaaagag tcatatgctt
     6301 tggtttatga aaaagacgca ttaccaaaca caggaagttc tcaatctatt atgactgcat
     6361 tgggtttgtt agctatcggg agtcttattg tgattatcac aaaagataaa aagaggaaaa
     6421 aaatcgctac atttttgatt gtaggggcga caggtttagt tacactatca actgcttcag
     6481 cacttaattt gaatgctaac atccatgagt ctggacgtga tggtgtgttg caaatttctg
     6541 gttacagata tgttgattac ttggagcttg atgatagaac tgtttctcca gttgagcaac
     6601 ccaaagttgt gaccgacaaa ggcgaaccag aagttcagcc agcgttacca gaagctgttg
     6661 taactggaaa agggaaaact gaagtacaac cgacattacc agaagctgtt gtgactgaaa
     6721 aaggggaacc ggaagtacaa ccagtgttac cagaagctgt tgtggctgaa aaaggggaac
     6781 cagaagtaca accagcctta cccgaagcag ttgtaactga aaaaggcgaa ccagaagttc
     6841 atgagaagcc tgactatacg caaccaatag gtgcaaacct tgttgagcct gaagttcatg
     6901 agaaactagc atacactgaa cctgtaggta caacaggagt agatgaaaat agaaacttga
     6961 ttgagccacc tgttaacgat attccagagt atactgaacc aatatctaca gtttcagaag
     7021 ttgcatcaga aagagaagag ttgccttctt tacataccga tattcgtaca gagactattc
     7081 ctaaaaccac tatagaagaa tctgatccta gcaaatttat aggcgataat tctgttaaac
     7141 aagttggtga ggatggcgaa cgtcaaattg ttactagcta tgaagagtta catggcaaaa
     7201 aaatcagcga gtcagttgaa acagtaacaa ttttgaaaga aatgaagcct gaaattattg
     7261 taaaaggtac aaaagaaaga ccaaaagaaa aaacggctcc tgttttaacc ttgaccaaag
     7321 taacagaaga tgctatgaat cgttctgcca acttaaatta tgagcttgat aataaagata
     7381 atgctgaaat atcaagtatt gtagctgaaa ttaaagatgg tgatacagta gttaaaaggg
     7441 ttgatttatc taaagaaaaa ttaactgacg ctgtacaaaa tttggatttg tttaaagatt
     7501 ataagattgc aacaacaatg atttatgatc gtggtcaagg ttctgaaacg tctaaactgg
     7561 atgaaagacc tctgcgtttg gagttgaaaa aggtcgaaat taaaaatatc gcatctacta
     7621 atttagtgaa ggtaaatgat gatggtactg aaacacctag tgattttatg aatgaaaaac
     7681 cttcagaaga agatgttaaa aaaatgtact taaaaatcac tagtcgcgat aataaggtaa
     7741 ctcgtttaac tgtagactct attgaagaag tgactgaaga aggtcaaaaa ctttacaaaa
     7801 taactgctga agcacaagat ttgattcaac acacagaccc aacgaaggtt cgtaataagt
     7861 atgtttatta tatagaaaaa ccccatccta aagaagataa tgtctactat aactttaaag
     7921 atttagtaga tgctatgaat actgataaaa atggtacatt taaacttggt gcagatttga
     7981 atgccactgg tgttccaaca cctaagaaat ggtatgttga cggcgacttt agaggtacat
     8041 tgaagagtgt agaggggaaa cattatacta tccacaacac ggagcgtccg ttattccaga
     8101 atattattgg tggtacagta accaaagtaa atctgggaaa tgtaaatatc aatatgccat
     8161 gggcagaccg catcgcaccg attgctgaca ctattaaagg tggcgctaaa attgaagatg
     8221 tcaaagtgac tggtaacgta ttaggtagaa actgggtatc tggatttatt gataagattg
     8281 acaaccaagg tacactcaga aatgtagcct ttatcggaaa tgtgacatct gtaggtgatg
     8341 gtggtcaatt cttgaccggt atcgttggtg agaactggaa aggactagtc gaacgtgcgt
     8401 atgttgacgc aaatcttatt ggcaagaaag ccaaggctgc tggtattgct tattggacac
     8461 aaaacagtgg tgacaatcat aaagttggtg tcgaaggtgc agtcaagaaa ggaattgtga
     8521 agggtaccat tcaggtagaa agtcctgttg aagtcggcgg tgctgttgga cgtttgagtc
     8581 atcatggtta tatcggggaa gtcgtatcta tgatgaaagt taagaagggt gaaatttttt
     8641 atggttctag tgatatgaat gatgacccat attgggtggc gaataatgta cgaggaaatt
     8701 atgtagttaa tggtgtgagt gaaggtacga tatcttatgc tcgtgctaaa gaacaccatc
     8761 gtatcaaacc aatttcacag tcagaagcag atactaaaat tatgatgtta ggtattacag
     8821 cacaagattt tgctatcaac gaacctgtgg tcaatcgctt aaaccgttta accagaaaag
     8881 aagatgaata taagtcaacc caagactata aagtagatcg agatctggct tatcgtaata
     8941 ttgagaaact tcaaccattt tataacaaag aatggattgt caaccaaggt aacaaacttg
     9001 cagaagattc aaacttagct aagaaagaag tcctttctgt tacgggtatg aaggatggac
     9061 agtttgtaac tgacttatca gatattgata agattatggt tcactatgct gatggtacta
     9121 aagaagaaat ggacgtcact aagaatgctg attctaaagt gaaacaagtt cgtgaatata
     9181 ccatcgctgg acaaaacgtt gtttatacac caaatatggt tgagaaagac cgtaaccaat
     9241 tgattcaaga tatcaaagat aagttggcgt cagttcaatt gatttctcct gaagtacgtg
     9301 ctttgatgga tgcacgtaag aaaccagaag aaaataccga tgaacgtaag aatggttata
     9361 ttaaagacct ttacttagaa gaaagctttg ctgaaacgaa agctaatctt gataaattgg
     9421 ttaaatcctt agttgaaaat gcagatcatc aattaaatag tgacgaagcg gctatgaaag
     9481 cacttgttaa gaaggtggat gaaaataaag ctaaaatcat gatggctctg acttatctca
     9541 atcgttacta tgatatcaag tatggggata tgactatcaa gaacttgatg atgtttaaac
     9601 ctgatttcta tggtaaatca gttgaccttc ttgatttctt gattcgaatt ggatcaagtg
     9661 agagaaatat caaaggtgac agaactttgg atgcttatcg tgatatgatt ggtggaacta
     9721 ttggtaagtc tgaattacat ggattcttag attacaatat gcgtctcttc actaacgata
     9781 ctgatttaaa tgattggttc atccatgcag ctaagaatgt atatgtatca gaacctcaaa
     9841 caacgaaccc agattttgtt aataaacgac atcgtgcatt tgatggtttg aacaacggtg
     9901 ttcataatcg tatgattcta cctctattaa ctcttaagaa tgcacatatg ttcttgattt
     9961 caacttacaa tacaatggct tatagttctt ttgagaaata tggtaagtat acagaagaag
    10021 ctagaaatga attcaaaaaa gaaattgata aggttgcaca tgctcaacaa acatacttag
    10081 acttctggtc acgtttagca ttgccaagcg tacgtgacca attactcaag agtgagaata
    10141 gggtaccaac tcctgtgtgg gataaccaaa actatagtgg tattaaagga ataaaccgta
    10201 tgggttatga tgagaagaaa gtaccaattg cgccaattcg tgagttatat ggtccaactt
    10261 ggaaattcca taataccaac tggaatatgg gagctatggc atctattttc ccaaatccta
    10321 ataacaatga ccaagtttat ttcatgggaa caaatatgat tagtccgttt ggtatttcag
    10381 cctttactca tgaaactaca cacgttaatg atagaatgct ttacttcggt ggtcatagac
    10441 accgtcaagg tacagacgtc gaagcctatg ctcaaggtat gctacaaact ccgtcaagta
    10501 ttggtcacca aggtgaatat ggtgctttag gtttgaacat ggcttatcat cgtgaaaatg
    10561 atggtgacca atggtataac tatgaccctg ataagcttca aactcgtgaa gatatcgatc
    10621 gatatatgaa aaactataat gaagcactga tgatgctaga tcatgtagaa gcagacgccg
    10681 tacttccaca attgaatggt gataatagca agtggttcaa gaaaattgat agagaaatac
    10741 gcagaaatct tggggatggt ttgaataact tagtagcacc gcaccaatgg gacaacgttc
    10801 gtgacttaaa tcaagaagag agttctaaga aattatcaag tattaacgat ttgattgata
    10861 ataatttcat gaccaaacac ggaaatccag gtaacggacg ttatagacca gaggatttta
    10921 gaccaaactc agcttacgta aatgtcaata tgatggcagg aatttacggt gggaatacga
    10981 gtcaaggtgc tcctggttca ttatcgttca aacataatgc cttccgtatg tggggttatt
    11041 atggatatga caaaggtttc actagttatg tatctagcaa atatcaaggt gaagctgata
    11101 aacaaaacca gggtagatta ggtgatgatt tcattatcaa aaaagtttca aacaaccaat
    11161 tctcaaatct tgaagattgg aagaaatatt ggtatcatga tgtgaaatcc agagctgaaa
    11221 aaggattcac agagattaca attgatggac aaaccattca caactataat gaactgaaag
    11281 acttattcga caaagctgtc acagaagacc tcaagaaagc tggaaactac tcaaatactg
    11341 agaatttgaa atccaaagtc ttcaaagctc ttcttaaaaa cacagacggt ttctttaatc
    11401 cattgttcaa aaaagacatt taaaccccaa ttatgcaccc ctaatctaaa aaccatccag
    11461 aatccttgcc ttagcttaga tcctggatgg tttctttttt cacccaatgg gtgtttttta
    11521 ctagacaaaa aagagtttcc cctttatggt ataagtgtag aaaaaaacac aaaaagaaag
    11581 gaaactcata tgaacagttt accaaatcat cacttccaaa acaagtcttt ttaccaacta
    11641 tctttcgatg gaggtcattt aacccagtat ggtggtctta tcttttttca ggaacttttt
    11701 tcccagttga aactaaaaga gcggatttct aagtatttag taacgaatga ccaacgccgc
    11761 tactgtcgtt attcggattc agatatcctt gtccagttcc tctttcaact gttaacaggc
    11821 tatggaacgg actatgcttg taaagaattg tcagctgatg cctactttcc aaaattgttg
    11881 gaaggagggc agcttgcttc acagccaacc ttatcccgtt ttctttccag aactgacgag
    11941 gaaacagtcc atagtttgcg atgcctcaac cttgaattgg tcgaattctt tttacagttt
    12001 caccagctaa accaactcat tgtagatatc gattctaccc atttcacaac ttatggcaag
    12061 caagaaggtg ttgcttataa cgcccactat cgtgctcatg gctatcatcc tctttatgct
    12121 ttcgagggga agacaggtta ttgtttcaat gcccagcttc gtcctggtaa tcgttattgt
    12181 tctgaagagg cagacagctt tatcacacct gttttagaac ggtttaatca acttctcttt
    12241 cgaatggata gtggctttgc gaccccaaaa ttatacgatt taattgaaaa aacagggcaa
    12301 tactacctca taaaactcaa gaaaaatact gttctgagcc gtcttggaga cctttccctc
    12361 ccttgcccac aggatgagga cttaaccatc ttgccccact ccgcctactc agaaactctc
    12421 tatcaagcag gatcttggtc gcacaagcgt cgtgtctgcc agttctctga acgaaaagaa
    12481 ggaaacttgt tctacgatgt tatttctctc gttacaaata tgacgagtgg aacaagccaa
    12541 gaccagtttc agctttatcg tggacgtggt caagccgaga atttcatcaa ggagatgaag
    12601 gagggatttt ttggcgataa aacggatagt tcaaccttaa tcaaaaacga agttcgtatg
    12661 atgatgagct gtatcgccta caatctctat ctttttttca aacatctagc tggaggtgac
    12721 ttccaaactt taacaatcaa acgcttccgc catctttttc ttcacgtggt aggaaaatgt
    12781 gttcgaacag gacgcaagca gctcctcaac ttgtctagtc tctatgccta ttccgaattg
    12841 ttttcagcac tttattctag gattagaaaa gtcaacctga atcttcctgt tccttatgaa
    12901 ccacctagaa gaaaagcgtc gttaatgatg cattaaagaa cagtcgagat gaaaaaatcg
    12961 tgtgacgcac caagggagga gtctgccctt ttgaggaaat ctagcgagga aaaacgatac
    13021 tggaacagca gaaagtaaaa ctgacctcat gaggaggaag aaagtggctc atgaggtcag
    13081 gggttttgta agttacatct agttgagaga ggtatgaatg atttggggtt tcaataacct
    13141 aactaagttt aattcagtta gatttacttg attttcttgg atgctataat caggattttt
    13201 atgtctagct tttttatagt aaaaatcgaa atctttttct gtaacttcaa gttgattcac
    13261 tatgtctttt gatgagaatt tactatttat caagttgtga gtctttttca attctaattt
    13321 tgtgtcataa attactatac tatttttaaa tctagttaaa ggatattttt cgagaccagg
    13381 tattgaagaa aatactttca gcaattggta ctttaaagta tttttgtata agcagtgata
    13441 ataaatagtc tcctgataat ctattttaaa actttctact tcaggggaag ggactagaca
    13501 attaccttga tctaaataca tagccataca ctcgtcaatt gtaagatgac gatatcgaag
    13561 ttgtactaat tgccaatcaa tattagtctg gtattgattt aaactataag acatagtttt
    13621 gaaacgattt gcatcatcgt cgttaagttt aatataaaaa tcgggattag gattataaat
    13681 aaaaaatctt ccgtcttcat tttcaatgaa gaaccaattt ttatagtctt ttaaaacatg
    13741 aaaatactgc tctttgatat ttaagtcggt atgattaaac ttttgaaaca actcatttat
    13801 taactcaaaa ggagcagagg agtctttagg ggtatttata gagccatttc tagcatatat
    13861 taatcctttt ggtaatgcag tatctttctt aggcttataa tcttttgtta aaaatacagg
    13921 aactttatct gtatcatgaa taattaagat
//
LOCUS       DAVLDI010000057        13611 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLDI010000057 DAVLDI010000000
VERSION     DAVLDI010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.057"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            171..1061
                     /locus_tag="VXD01_001815"
     CDS             171..1061
                     /locus_tag="VXD01_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602163.1"
                     /translation="MDNTKVIEWLNYCDQNDIKPWLWDFKNCYSSELTADNISNFLKY
                     KNGELVNPSTFCITKQVGSNADCDKEALPLYNVLGWQHSERDIIRGETLNSYITTFTQ
                     AITNDPNYKEICKKIGVNLNEYLNKQYPILHHNKNYQNFKMIQKNLKEFEAFAKLTHT
                     IGNFTVLPHWMNTGRYNFSKDYWDITMLSLQEWLTNLSPQAWKNFIDTYYLQPYVDNN
                     YQTEVFWETHNYEYIYPKKTEDFSIFLKRVNERIEERGKFIIKQICDKLNKKDFHFYK
                     EIENMDKIKYSNEFEQERKQ"
     gene            1058..1528
                     /locus_tag="VXD01_001816"
     CDS             1058..1528
                     /locus_tag="VXD01_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602164.1"
                     /translation="MTRVYKSVRLAYEAKVWIDELIQEKERKIQELNKEDFLDKLEKT
                     LLKNHYDELNGLSFNIILKASIGSVIEESYRNTKHYPIDKWQKLRQQMERDVKNVNPN
                     LETTVTPRIYLDEDVLAGLDDFRYVLMKEDCATRLPRLSYIIKLVVYSYWKEQH"
     gene            1615..2283
                     /locus_tag="VXD01_001817"
                     /pseudo
     CDS             1615..2283
                     /locus_tag="VXD01_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476106.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
     gene            2243..3424
                     /locus_tag="VXD01_001818"
                     /pseudo
     CDS             2243..3424
                     /locus_tag="VXD01_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678337.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(3687..4079)
                     /gene="rpsI"
                     /locus_tag="VXD01_001819"
     CDS             complement(3687..4079)
                     /gene="rpsI"
                     /locus_tag="VXD01_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV0602165.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(4099..4545)
                     /gene="rplM"
                     /locus_tag="VXD01_001820"
     CDS             complement(4099..4545)
                     /gene="rplM"
                     /locus_tag="VXD01_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV0602166.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            4901..5218
                     /locus_tag="VXD01_001821"
     CDS             4901..5218
                     /locus_tag="VXD01_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV0602167.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(5263..6075)
                     /gene="folK"
                     /locus_tag="VXD01_001822"
     CDS             complement(5263..6075)
                     /gene="folK"
                     /locus_tag="VXD01_001822"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV0602168.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQVNLKQAIDKLRARGIHILKESSVLET
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(6118..6672)
                     /gene="folE"
                     /locus_tag="VXD01_001823"
     CDS             complement(6118..6672)
                     /gene="folE"
                     /locus_tag="VXD01_001823"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV0602169.1"
                     /translation="MDTQKIEAAVKMIIEAVGENVNREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(6653..7975)
                     /locus_tag="VXD01_001824"
     CDS             complement(6653..7975)
                     /locus_tag="VXD01_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV0602170.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVIHI
                     GGTNGKGSTIAFLKNMLEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLEALMVDY
                     QSLLEGGVASNFQETTEFEIITALAYNYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEVIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADH
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLDQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(7977..8957)
                     /gene="folP"
                     /locus_tag="VXD01_001825"
     CDS             complement(7977..8957)
                     /gene="folP"
                     /locus_tag="VXD01_001825"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV0602171.1"
                     /translation="MVKSLEGVTDMSTKVNHAKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTWKSQVAEAALAAGANLVNDITGLMGDEKMAEVVAKAGAKVVIMFNPVIARPQHPSS
                     LIFPHFGFGQAFTEEELANFEKLPIEDLMETFFERALARANQAGIAQENILLDLGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHKMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(9052..9759)
                     /locus_tag="VXD01_001826"
     CDS             complement(9052..9759)
                     /locus_tag="VXD01_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0602172.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSIVLSWTAYKTQRLEMSILLHMIVNGVAF
                     CLLALVVIMSRTLGISV"
     gene            complement(9812..11230)
                     /locus_tag="VXD01_001827"
     CDS             complement(9812..11230)
                     /locus_tag="VXD01_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV0602173.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            11420..12232
                     /locus_tag="VXD01_001828"
     CDS             11420..12232
                     /locus_tag="VXD01_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV0602174.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            12571..13590
                     /gene="adhP"
                     /locus_tag="VXD01_001829"
     CDS             12571..13590
                     /gene="adhP"
                     /locus_tag="VXD01_001829"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV0602175.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIATADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         4366 a         2844 c         2483 g         3918 t
ORIGIN      
        1 attataacaa atattctgaa atttaacgct atgaaattta aatatagcca taacttacaa
       61 tccacaaaaa aatatttgaa aaaatttttt tctaaatctc ttgcattttc tgaaaaaata
      121 gttataataa aagtatagtt gttttacaac aaaatagaat aggtagaatt atggataaca
      181 caaaagttat tgaatggtta aattactgtg accaaaacga tatcaaacca tggttatggg
      241 attttaaaaa ttgttactct agcgagttaa ccgcagataa tatttcaaat tttctaaaat
      301 ataaaaatgg agaactcgta aatccttcca cattttgtat cacaaaacag gttggtagta
      361 acgctgactg cgataaagag gcactcccac tttataatgt tttaggttgg caacattccg
      421 agagagatat aataagaggt gagaccttaa attcttatat aactacattt actcaagcta
      481 ttaccaatga cccgaattat aaagaaattt gtaaaaagat tggagtaaac ttaaatgaat
      541 atctaaacaa gcagtatcca atcttacacc ataataaaaa ctatcaaaat ttcaagatga
      601 ttcaaaaaaa cctaaaagaa tttgaagcat tcgcaaaatt aacacataca atcggaaact
      661 ttactgtatt gcctcattgg atgaatactg gacgatacaa tttctcaaaa gattactggg
      721 atattacaat gctttctctt caagaatggc ttactaattt atctcctcaa gcatggaaaa
      781 attttattga tacatactat cttcaaccct atgttgataa taactatcaa acagaggtat
      841 tttgggaaac tcataactac gaatacattt atcccaagaa aaccgaagat ttctccatct
      901 tcctaaaaag agtcaatgaa cggattgagg agcgcgggaa attcatcatt aaacaaatat
      961 gcgataaact aaataaaaaa gatttccatt tctataagga aattgaaaat atggataaaa
     1021 ttaaatactc aaatgaattt gaacaagaga ggaaacaatg actagagtat ataaaagcgt
     1081 ccgccttgcg tacgaggcaa aggtatggat agatgaattg attcaagaaa aagaacgtaa
     1141 aattcaagaa cttaataaag aggattttct agataaactt gaaaaaacac ttcttaaaaa
     1201 tcactatgat gaattgaatg gtctttcatt taatatcatt ctaaaagcct caatagggag
     1261 tgtcatagaa gaatcctatc gaaatactaa acactatcca attgacaaat ggcaaaagct
     1321 acgtcagcag atggaaaggg acgtaaaaaa tgttaatcct aacttagaaa ccacagttac
     1381 tccccgtatt tatctagacg aggatgtgct tgctgggctt gatgattttc gctatgtttt
     1441 gatgaaagag gactgtgcta ctagactacc tcgtcttagc tacattatca aacttgttgt
     1501 atattcctac tggaaagaac aacactaatc taatcagttc tactgtttag attttcattt
     1561 ctttaaaatg tatatttgtt gtactactaa taaatctaga aaaataggta atctatgttt
     1621 aaattaaaga aagtcgctga cttaaaaaga aattatatca tttcaactaa caaattaaag
     1681 gtaactcatt ggtcaatatt aagcctctct atctgcatta tgcttactat tattgcaaat
     1741 attagagccc ctgaccttat taaaatccct ttacttattc tagtaggatt tgtcatatac
     1801 aaatttcatc gtcaattaaa atattttaga tataatttag attattacct aattatcaga
     1861 gaaagcttat tgtatgtatt acatacaaac cgcctttata caacacataa agatagctca
     1921 ggatatgaaa aaatctctag gagcgcaatc ttacaatacg agttagacaa acaaaagggg
     1981 catatcttta tcaaagctct gattactggt gatgaattta gtaaaagggt acaatcactt
     2041 gatgatgttc ttgctggagt actcgaactg gaactagaat acaaaattat tcgtcctagt
     2101 tttatggaat accatttcta ttacaagaaa cctgacaggt tagttcttca atctcacaac
     2161 cagaagcaag agatagataa ccttaatata gatttaggat acggtgtgaa ttataatcct
     2221 atcaagtgtc ctcatattct agttgccgga ggtacaggaa gcgggaaatc agtatttata
     2281 tctttaagga aatcactttg ttaaacgcta taaaacaaga aaggaggcta aagaagctga
     2341 attagaaatt ctaacaaaga tacatcaact tgaaaatgga gaggatatcc cactccttaa
     2401 aactagtgat attcttttct ctgagttctt taataatatt tggtgggatt catacaaagc
     2461 tggtcaaaca acttcaacaa ctaaaccccc aacacaagtt actattgata atactgaaat
     2521 agttttcagg aagcacatct taccaatgtt cggtaattat tcaatcaatt ttctgaatca
     2581 gaataagcaa atcgtactaa acttaatgac tgctaaagct gaagaatatg ctaatttcaa
     2641 ggttattcga agctatgtaa actcaatttt cgattgggct gaagaattag aatacattga
     2701 atcaaataga ttatcaaaaa gcataaaacg tattaaagca agtaaaaaaa taaagctaga
     2761 agaagctaag gatgaggaag atttgtatct atctagtgaa gaattacaag attggtttga
     2821 tgcttttaga gaagatttgg agaacgacaa attatcacta aaagattatg tcctattctt
     2881 tacaaccttt attttgagcg atagaaaatc agaatcctat gctctacatt ggaaaaacat
     2941 agacttggca aacgctcaaa ttggcttaag gcatgcactt gacaaatata agaatgtaaa
     3001 gtcaacaaaa ggaaataaga aaacgatttt ttcaattcct agttaccttg tatcacttct
     3061 ttcagaatgg aaaaaacagc agaaatatga gttagcgaaa tttggtataa tgcaaacatc
     3121 cgatcaacta gtctttacct atatagatac gaaaggtaat gtaaatagcc ctctacacgt
     3181 tgattatctc aataacaaaa tgaactctgt aaaaagacga cacccaaagt taaaacacgc
     3241 tacacctcat aaattacgac atacaggagc gacacttgct aaaaaggcag gaatgagctt
     3301 agaagccatt tctgaagtat taactcatag tgatacaatt acaactaaaa cttatgttaa
     3361 tgcttcaaac atagttccat tatctgctgg acaagttgcc taccaacatc ttaaaaacaa
     3421 gtagggtaat tttagggcaa attttaggga aaactttttt agaaagtata gaaaaaagca
     3481 cccatagggc aaacctttga gtgctttgaa acattgatat aatcgtattg attaacgttt
     3541 tgaggcaact gaccttgtca ggttgcagcc acatttgtaa gcgactaaag tcgcaacaac
     3601 tgtgtcaatt gcaccaattt agtaagaaag tataaaaaaa gaacaccccg aaaggtgctc
     3661 tgtataagta tagtaattct ttcgaattaa cgtttactaa attgtgatgc tttacgagct
     3721 ttcttaagac ctggtttctt acgttcaact ttacgtgagt cacgtgtaag aagtcctgcg
     3781 cgtttcaatg aatcgcggaa gtctgggtct acttgaagaa gggcacgagc gataccgtga
     3841 cggatagctc ctgattgacc agcgtatcca ccacctacaa cgttaacgaa aacgtcgtat
     3901 gaacctacag ttgaagtaac tgcgaatggt tggttgatga caagacgaag gtcagcgtgt
     3961 gggatatact cttcaacatc ttttttgtta acagtgattt taccagttcc tggaacaagg
     4021 cgaacgcgtg caacagcgtt tttacgacgt ccagtacctg catattgtgc ttgtgacata
     4081 ctttatttgt tcctttcctt agataagtcc tgaaatgtca agaacttctg gttgttgtgc
     4141 agcatgagtg tgctcagctc caacaaatac tttcaacttc ataccttgag cgcgtccaag
     4201 tgtattgtgt ggaagcatac ctttaactga tttctcaatc aaacgtactg catttttaga
     4261 acgaagttca cctgcagaga tttgtttcaa tccacctggg tggtttgagt gagtgtagta
     4321 gattttatca gttgcttttt taccagtcaa tttaactttt tcagcattga taacaatcac
     4381 gaagtcacct gtatcagtgt gtggtgtaaa tgttggtttg ttttttccgc gaagtacgct
     4441 agcaactact gcagaaagac gtccaagtgg tacatcagtt gcgtcaacta cgtaccattt
     4501 acgttcaact tggcctggtt tagccataaa tgttgttttg ttcatgattt ctcctatata
     4561 tagttcgatt tttgtttacg gtgatgggtg ttccttccca tcgaaaagta tttggaaggt
     4621 tccggggcct ttcaaatggg gtaaacaata ccgcctacta tcataccaaa tttcacccct
     4681 aaaagtcaat agatataaaa aatatttttc ggtaacttct caaaataact gaaagttata
     4741 taatcaagtt aatttgggaa tttacctatt aacttcggta gatttttggg aattttttcc
     4801 ctatttctcc ctgtaactaa aatccttttc aaaaaatcac cttttcttga tttttaatcc
     4861 tatttgctgt atgataaggg aaaagaaagg ggacagagat atggctttta ccaataccca
     4921 catgcggtct gctagttttg gcattgttac cagcttgccc gatgacatca ttgactcttt
     4981 ttggtatatc atcgatcatt tcttaaaaaa tgtctttgaa ttggaagaag aactcgagtt
     5041 tcaattgctt aataaccaag gaaagattac cttccacttt tcaagtcaac acctccctac
     5101 agccattgat tttgacttta accatccttt cgaccctcgt tatcccccaa gagtactggt
     5161 tttagacatg gacggtagag aaactatcct cctcccagaa gaaaatgacc tattttaaaa
     5221 actctagcct tcagttgcaa gtaactgaaa actagagttt ttctattttt tcaaagcatc
     5281 atacaagttg cggatcggtt gttttaatat cggatggata aaatgaggcg caatttcctg
     5341 taaggactca aggacaaaaa ggcgttccgc tatgtaagga tgaggcaata tgaggtcgtc
     5401 tgtataaagg atctggtcct ccacaaagag caagtccaaa tcaatcaaac gaggtcccca
     5461 atgcacttct ctcacccgtc ccagctctga ctcaatggct aacaaggttt ctaacaagtc
     5521 ttgtgctggt agccaggttt ccacctcaac cacttgattg gcaaagctat cctgctccac
     5581 tccaccccaa ggctccgtct ctaagacact ggactctttg agaatatgga tgccacgagc
     5641 tcgcagtttg tcaatggctt gcttcaagtt tacttgttta tctcccatat tgcttcctag
     5701 ggcgataaag gctcgttgct tgcggcgatg aatggttacc gagcaagtat ctagtgacaa
     5761 atgcaccggt gcccaaggtt ttttcagttc caacttcatt tcttggacaa gaggataaga
     5821 ctcaaaggta cgttccacca gtttataggc taccgtttca atcaaatctt cactcgtttc
     5881 ctgaaaccaa gtcgtccact gctgacacaa ttctccgtaa tggacagagg ctgttaaatc
     5941 caagtctgta gctgccttgg tcatatcata ggataggatg gctgaaacga caaatttctg
     6001 ccccaattct ttctcactag gaaaaagacc atgataggca aacatttcca aatccttaat
     6061 ctgcagttga tccataatga ttcctttcta gaaaaatccg cttgaagcgg attcttttta
     6121 tagccccatt aaacgataag cttggtcacg gagatcctta tctgtttcaa atagaccacg
     6181 agctactgtc gtcaaggttg cagtgcctgg ttttctaaca ccacgcatac tcatacacat
     6241 atgttccgcc tcaatgacaa caaaggctcc tttagcacct agatagtcca tcaaggcatc
     6301 ggccacttcg atattcaaac gttcttgaat ttgtggtttt ttcgaataaa cttcaaccgt
     6361 acgggctagc ttagacaagc ctgccacacg accatctgga atgtaggcaa tgtgcgctct
     6421 accataaaat ggcaagaagt ggtgttcaca catggtatgg aaaaagatat ccttttctac
     6481 caccatatta tcgtcaataa tttcaaagga ttttgacaaa tgttcctctg ctgtttgacc
     6541 aagacctgaa aaaatctctt gatacatacg ggctacacga gcaggtgttt cctgcaagcc
     6601 ctcgcgatta acgttctctc ctacagcctc gataatcatt tttacagctg cttcaatctt
     6661 ttgtgtatcc attctcgttc ttcctctcca tcagataggc cctcacttgg ctcaagaaat
     6721 acaaggaacc tgtgacaatc ctaactgttt gtttctcttc ttttttatct gtcaaattct
     6781 gatctagaaa atcatgccaa tcttggtagc tgagatttct agacttagct gcctctttca
     6841 gcacgctttc atccgtcgcc cgactatccg caaaatgtgt tagagtaagc tcggtatctg
     6901 gcatggctcc cagcaagtcc aacatatcct ccaaggcttt ggttttgata caagtgaaga
     6961 ggatttcctt atgatgatcc gcaaaacgtt cttgcaaggt taccaacaag gccttgatag
     7021 catggggatt atgggctcca tccaaaatca tcaagggatc tcttgacacg atttccaaac
     7081 gccctggcca acttgtttct tccaaggctt gaccaagaaa gtcattgctt gctagctctc
     7141 gaccatcttc ttgacaaaaa gtatcaagta aagctatggc catcccagca ttctctattt
     7201 ggtacaaacc aagcaggcta gtctggaagc gaccttgtct gacagcactt gtatagtcaa
     7261 agacttcccc tgtcaccaca ctttcttgat gacgaacctg ataatctgtc ccgtaggcaa
     7321 gtctcggcgc atctttccct tccgcaatgc ggtcaatcac agtcaaggct tctggagcaa
     7381 tacgccctgt taccaagggc atcccttgtt tgataatacc tgccttctgc tctgctatga
     7441 cctccaaggt gtcaccaagt agggccacat gatccaagcc aatagttgta attcctgtca
     7501 aaatgggctg acagacattg gtactatcca aaagtccacc catgccaact tccatgatgg
     7561 ccacatctac ttgctctgag gcaaagtagt tataggccag ggctgtgata atctcaaact
     7621 cagttgtctc ctgaaaattg gaagccactc ccccctccag caaagactga tagtctacca
     7681 tgagggcttc tagtctagcc tccgggatag attccccatt gatgctaatc tggtctgtat
     7741 aatgaatgag atagggcgag ctgaaaacac caactctcag ccctagtttt tctagcatat
     7801 ttttcaaaaa agcaatggtc gaacccttgc cattggttcc tccgatatgg atgactttga
     7861 gtttgagatg gggatttccg cgcaaagcta acagttccac cattcgttcc aagccaaaat
     7921 gcggttgatc cgtccggtag ttagcaatcc actgattgtt ttcaatttct ttcatcttat
     7981 ttatattgtt ttaaatctaa attttccgct tcatcagcca atcgaatggc tgatgcaatt
     8041 tcaactgcca tcttgtgact ggctacgtca tgcacgcgca ccacttctac accctgtctt
     8101 gcagcgatac tggttacatg agccgaagcc gtatctcgat tgcggaaacc aagttctgtc
     8161 tcaggattga cttcaaaacc attttcttca agaatattga tgacaaaccg cttacgcgac
     8221 actccaagaa agattggata gcccttctga tgtagtttat ccaaatcccg taaaagaagc
     8281 aaattttctt tcttggtcag accaaagcca attcctagat ccaacaggat attttcttgt
     8341 gcaattccag cttgatttgc tctcgctagt gcacgttcaa agaaagtctc catcaagtct
     8401 tcgattggca atttttcaaa gttagctaac tcttcctctg taaaagcttg tccaaaacca
     8461 aaatgaggaa agatgagcga gctaggatgc tgaggtcgag caataactgg attaaacatg
     8521 atgaccactt tcgcaccagc cttagcaacc acctccgcca ttttctcatc acccataaga
     8581 ccagtgatat cattaactag attggcacca gcagccaaag cagcttctgc tacctgactc
     8641 ttccaagtat caatagagat gaggacatca ctttccttgc gaatcgcttt aatcactgga
     8701 acaacacgct ggatttcctc ttctatctca acatagctat agctacttcc cggccgagtc
     8761 gattctccgc cgatatctag catactagcc ccttctgcta tcaatttacg agcctgctgg
     8821 agtgcctgct caagagcaaa aaattgacca ccatccgaaa aggaatctgg ggttacattg
     8881 ataattccgc aaatagctgt ctttgcatga tttactttag ttgacatatc ggtcactccc
     8941 tcaaggcttt tcaccatatt atttctctat tttaccataa aaagaaaaag atggacacta
     9001 ttgcattcat cttttttccc aatagaaaca agtaagcaat tgtcaaaaat cttaaacaga
     9061 aatccctaat gtccgactca ttatcaccac aagtgccaat aaacagaagg ctaccccatt
     9121 aacaatcatg tgaagcaaga tagacatttc caaacgttga gtcttgtaag ctgtccaaga
     9181 tagaacgatt gacatacctc cataaatcaa taaagaaggt aaattacttg gttgatgcaa
     9241 taaagcaaag acaatcgtac caaccacaaa ccccaagttc tccttgcctc gaaaaatctt
     9301 tttaggaaca atcccacggc acaagatttc ctcacaaatc ggagcaagca aggctagcaa
     9361 gaagaagcta gaaatcagag aactattctg aaccatatcg ttaatctgag actggttagc
     9421 tgttgtcgtc tcatttgaca gttgcaacaa gatagaacca agtatatttg acccgacaat
     9481 aactaaataa ctcaagccca aacgtgccaa atctttagct ctaaaaaaag aaaaattaaa
     9541 actagctaac ttggttttac gagctcccat aataaataga gccagaacca caattgaaag
     9601 gccagcaact atcagccctg actgtagcag ggctacttct tttaaagtca aaatagaggt
     9661 aaccactagg ggaacctgat ataaaaggac ggcaagtaaa aagaccaaaa tccagcctgc
     9721 acgattcaac aattctttcc acatattttt ctcttttatc acctatctcc tttgtattaa
     9781 aaaagggggg aaatccccct gggtcattct attataaggc catgctgatg tagttaagga
     9841 taaacaaggc atccaaaatc caaatcatgg catgaacatc tttaacttga cctttgacaa
     9901 gcttagtcaa agtgtaagtc aagaaaccaa ctgcaatccc ttgagtgata gagtagctga
     9961 atcccataaa gatagatgtg aagaaggcag gaactgcttc agacatatca tcccaatgga
    10021 tatttttcaa gctaccaagc atcataatcc caacgataat caagattgga gctgtagccg
    10081 ctgttggtac gatcgctaga agcgggctaa agaagcttga aatcgcaaaa cagatagcta
    10141 caaccaaggc tgtcaaacca gtacgtccac ctgcaccgat accagcagca gactcaacat
    10201 aagtcgttac gtttgaagta cctgcaatgg caccgactgt cgttccaatc aaatcagagt
    10261 aaagagcctt atccaatttg gctgattggt gattttcacc atttgtcgct acaataccaa
    10321 ctttttcacc tgtaccgatc aaggtaccaa ttgtgtcaaa aatatctgtc aatgagaagg
    10381 caagaatggc catcagagtt tcaggcaagc gagctgtatc tgaaaccaaa gctcccaaac
    10441 cttctgaacc aagagctgca ccaaagattg tcttcaaatc ttcaaaagct gcaccaacat
    10501 ggttattagc aaaatcgata ctagacaaat caaccaaacc aactgcaata gcaagaacag
    10561 ttgttgtcaa gatagagaga ataattcccc ctttaatccc tttgatgaca aagaagatag
    10621 taatggcaag tcctgcaaga gccactaaaa cagctggatt attaaagctg accaatcctg
    10681 gaactgctga agagtttgct gcaatcgttg cttgagcttt gtcagcccct tctcctacaa
    10741 cagtatagtt gcctggatca atcgtgaatt tcaaaagtcc agcattctta atccctacat
    10801 aggcaaggaa gacaccgata ccagctgaaa tagctgagcg aagagcattg ggaatcgatt
    10861 caatgatcat tttacgaaca tttgtcaagg taataatcaa tgaaataatc ccacagatga
    10921 agaccatagc tagggcttct tgccaagaat aaccaagccc gaatacaact gtaaaggtaa
    10981 agaaggcatt gagtcccata cctggcgctt gggcataagg taagttagca taaaaagcca
    11041 tcatcaaggt acccgctact gcaccaataa tcgtcgctag gaagacgccc tgagcaggca
    11101 ttcctgtttg tgaaagtatt tgtgggttta caaagagaat atagctcatt gcaaagaaag
    11161 ttgttaaacc agcgagaacc tctgtacgaa cgtctgtacc gttctctttt agtttaaata
    11221 atttgtccat catcaatctc cttttaattt ttacgaacaa taatagaatt atatcattta
    11281 tcattcactt tttcaatgtc tttgtttgat ttgtttaaga aattaatcca atttcatttt
    11341 ttgtttggaa tctgcttttc tgcctgcttt ctgttataat agaagacatc ttatctgaaa
    11401 acacactaga aaggtccata tgacgaaaaa aattattgca gttgacctgg atggaaccct
    11461 gctcaactca gacagtcaaa tttctgactt taccaaaaaa accatcaaaa aagttgctga
    11521 aaaaggccat caggttatta ttacgacagg tcgcccttac cgtatgtcaa aagattttta
    11581 ccgtgaactg ggcttagaca ctcctatgat taacttcaac ggatccctta ctcatttacc
    11641 agaccaagtt tgggattttg aaaagtgttt gactgtagac aaaaaatatc tgctagatat
    11701 ggttcaacgt tcagaggaca ttcaagccga ttttatcgct ggagaatatc gtaaaaaatt
    11761 ctacattaca aatcccaatg aagaaattgc caatcccaaa ctatttggtg tagaagcttt
    11821 ccagcctgaa gatcaattcc agcctgaatt ggtgaccaag gaccctaact gtatcctctt
    11881 gcagaccaga gccagtgaca aatatgcctt ggcaaaagac atgaacgcct tctaccagca
    11941 tcaactttct atcaatacct ggggaggtcc gctcaatatc cttgaatgta ccccaaaagg
    12001 tgtcaacaag gcctttgctt tggactactt gctcaagata atgaatcgtg acaaaaaaga
    12061 tttgattgcc tttggagatg aacacaatga taccgaaatg ctcgcttttg ctgggaaggg
    12121 ttatgccatg aaaaatgcca atccagagct actcccttat gcagatgagc aaatttccct
    12181 taccaacgac caagatgggg ttgccaaaac cctacaagac ttattcttat aacctatact
    12241 gatactcaat gagaatcaaa gagcaaacta ggaagctagc cgtaggttgc tcaaagcact
    12301 gctttgaggt tgtagatgaa gctgacgtgg tttgaagaga ttttcgaaga gtatgaccag
    12361 cttgcaagct ggtctttgtg ctcttttcac agtctcatca accagttaat cgattgttct
    12421 actttttgtc tccaaaacct tggaaaaggc ttccttttgt gatatacttc acatataaat
    12481 acaagagagc tcgtcacact cgactctgtt gacaaaaaat caatccagtc ccgttgtccc
    12541 tgttctcggt caatatcaag gaggatagct atgaaagctg ttgttgtaaa tccagaaagc
    12601 actggtgttg ctattgaaga aaaagtactc cgtccacttg aaactgggga agcacttgta
    12661 gaagttgaat actgtggcgt ttgccacacc gacctccacg ttgctcatgg tgactttggt
    12721 caagtcccag gacgtgttct tgggcacgaa ggtatcggta tcgttaaaga gattgctcca
    12781 gatgtgaaaa gccttaaagt cggtgaccgc gtcagcgttg cttggttctt tgaaggatgt
    12841 ggcacttgcg aatactgtac aactggtcgc gaaacccttt gccgtacagt gaaaaatgct
    12901 ggctactcag tagacggtgg tatggctgaa caatgtatcg caactgctga ctatgctgtc
    12961 aaagttcctg acggacttga tccagcccaa gcttcttcta tcacatgtgc tggagtaaca
    13021 acctataaag ctatcaaaga agcaaaagtt gaaccaggcc aatgggttgt tctttacggt
    13081 gctggtggac ttggtaacct cgctgttcaa tacgctaaaa aagtattcaa tgctcatgtt
    13141 atcgcagtcg atatcaacaa tgacaaactt acccttgcaa aagaagtagg cgctgacatt
    13201 gtgattaacg gcctcgaagt tgaagatgta gctggactca ttaaagaaaa aactgatgga
    13261 ggagctcatt cagctgtcgt aactgctgtg tctaaagttg ccttcaacca ggctgttgac
    13321 tccattcgtg ctggtggtcg cgtcgtcgct gttggtcttc cttctgaaat gatggaactc
    13381 agcatcgtta aaacagtcct cgatggaatc caagtcatcg gttctcttgt cggaactcgt
    13441 aaagacttag aagaagcctt ccaatttggt gcagaaggtc tggtagtccc agttgttcaa
    13501 aaacgtccag tagaagatgc tgttgctatt ttcgacgaaa tggaaaaagg ccaaatccaa
    13561 ggacgtatgg tactcgactt cacccactaa tttaatagaa acctatttta a
//
LOCUS       DAVLDI010000058        13401 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLDI010000058 DAVLDI010000000
VERSION     DAVLDI010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13401
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.058"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(161..1792)
                     /locus_tag="VXD01_001830"
     CDS             complement(161..1792)
                     /locus_tag="VXD01_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV0602176.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFISAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2085..7064
                     /locus_tag="VXD01_001831"
     CDS             2085..7064
                     /locus_tag="VXD01_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV0602177.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7154..8350
                     /locus_tag="VXD01_001832"
     CDS             7154..8350
                     /locus_tag="VXD01_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV0602178.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADNVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8486..9013
                     /locus_tag="VXD01_001833"
     CDS             8486..9013
                     /locus_tag="VXD01_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV0602179.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFCFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9090..9446
                     /gene="glnR"
                     /locus_tag="VXD01_001834"
     CDS             9090..9446
                     /gene="glnR"
                     /locus_tag="VXD01_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV0602180.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9483..10829
                     /gene="glnA"
                     /locus_tag="VXD01_001835"
     CDS             9483..10829
                     /gene="glnA"
                     /locus_tag="VXD01_001835"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV0602181.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10919..11038)
                     /locus_tag="VXD01_001836"
     CDS             complement(10919..11038)
                     /locus_tag="VXD01_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV0602182.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11296..11433
                     /locus_tag="VXD01_001837"
     CDS             11296..11433
                     /locus_tag="VXD01_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602183.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEALNIRLEVK
                     N"
     gene            11583..12902
                     /locus_tag="VXD01_001838"
     CDS             11583..12902
                     /locus_tag="VXD01_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0602184.1"
                     /translation="MPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDGINWIKIGDT
                     EKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAIS
                     NYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRIV
                     EAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLL
                     EKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYGNKDETSSYPIYEIPEAWRYIKF
                     ASLVNFRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDIS
                     PKGTLLMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGD
                     SKDAIKGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(12850..13395)
                     /locus_tag="VXD01_001839"
     CDS             complement(12850..13395)
                     /locus_tag="VXD01_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0602185.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT         4374 a         2401 c         2798 g         3828 t
ORIGIN      
        1 cagtcaaatc gatttctaac aatgttttag aaatagaggt gtactattct agtttcaata
       61 tattatatat ctgcagaata ctctttcagt ttcattcagc ctagtcttgc ttaggaaaaa
      121 gtaagaagcc atccaattat gatggatagc ttcttggtta ttagatttgt tctgcaaaaa
      181 ccttttcagc aaggttcata gcgtggtctg atacacgagt gtagtgtgag atgatgtcga
      241 taaagttgac cccagcttgt gttgaacatt cgcctttgtt gaggcgtttg atgtgggttt
      301 ttctgagaac acgttctatc ttattgattg cttcatgacg ttctacaaga ctgcgtgctt
      361 tttcaatatc attgttttcc acactatcca gagcatcttt gataaagtca ctagtttggc
      421 ggtaaacttc ctctaattct ttcaaggcgg catcagaaaa ttcaacattt ttccgttgaa
      481 gatagtcagt cagattgagt agagcctccg tgtggtctcc aatccgttcc aaatcacggg
      541 aggaatcaag gatattggta agcacttcac tttctttttg gctgagagct tcgcttgaaa
      601 gggcaatgag ataacgtgtt aattgctcat cgatggtgtt aattgcttct tcggttttat
      661 gccctttttc agcaactttt tcatccaagt caatgatgta cttataggaa aggtcaaagg
      721 ctttagcagc gtagtttcct aagtgcaaga gctctttctt agcatttcct agagcgatag
      781 atggggcctg tttgatgaaa tgttcatcaa gatataaggg ttcgtatttg acaacctcgt
      841 cctctccagg aataatcttg gttacaaagt aagccagagc tccgataaat ggaaattgga
      901 caatggtgtt ggtaatatta aaggttccgt gagcaaaggc gatggtcatt tccggtgcta
      961 gatttagcgt agcttcaaac caatgaatca ggacagtaaa aggaactaga aaaataacgc
     1021 agacaactgt tccgataacg ttgaaggcaa catgagctcc tgctacccgt ttagctgcaa
     1081 tattagcccc taaagaggca atgatggctg taatggttgt cccgatattg tcaccaaata
     1141 gaactggcaa agctccctgt agatcaatta gattgccggc gtagaggttt tgtaaaatcc
     1201 caatggtagc cgaagaagct tgaattagca aggtcaagcc agtaccgaca aagacaccca
     1261 aaacaggatt cttacttagc tcaatcatat agtccttaaa gacctgtaaa tccttgagtg
     1321 gagccattgc gccgctcatg agattgaggg caaaaaagat accaccgaca ccaaagagga
     1381 tgcgtccgat attattgact gtccgatttt tcgtaaaaaa aagacagacg gcactgataa
     1441 agagcatagg tagggcatag ttacctaatt taaaaccgat gagaaaggat gtgacagttg
     1501 tcccaatatt agcacccatg acaatcccga tagcctgacg taaggttaag agaccggcac
     1561 tgaccaggcc gactgtgata actgttacac cagaactaga ctgaattaga gcagtcatcc
     1621 caataccaac cagaactcca aagaaaggat tactagtata tttgtcaatg taaaaacgaa
     1681 ggcgatctcc agcagcttgt tgtaaaccgt ctcccatggt cttgatgcta tataagaata
     1741 gccccagacc acctaaaaag tgaaataaaa tttcctgcca attaatggac atttcttttt
     1801 cctccgaaaa ataatcgcgg aatatctcct attctatttt aaaggataaa agtaaatcta
     1861 acaagtgtta atgtcaagtt tgtaaaagaa aattataatt gataagtgta ttatttttaa
     1921 gagtttttaa ccttatttta gatttgtgca aacagttatt gttttttgtc taaaaatgtt
     1981 ttaggataaa aatgtgatta tcatggttct agagtttgat aaaaaactac agaatataaa
     2041 gcactttctt gaaaacaaca aaatcaatct tttaggagga gaaaatgaag aatccatttt
     2101 ttgaaagacg ttgtcgttac agtattcgta agttatcagt aggagcctgc tcgctgatga
     2161 ttggtgctgt tttatttgct ggtccagcct tggctgaaga aactgcagtt cctgaaaata
     2221 gcggagctaa tacagagctt gtttcaggag agagtgagca ttcgaccaat gaagctgata
     2281 agcagaatga aggggaacat gctagagaaa acaagctaga aaaggcagaa ggagtagcga
     2341 tagcatctga aactgcttcg ccagcaagca atgaagctgc aactactgaa actgcagaag
     2401 cagctagcgc agctaaacca gaggaaaaag caagtgaggt ggttgcagaa acaccatctg
     2461 cagaagcaaa acctaagtct gacaaggaaa cagaagcaaa gcccgaagca actaaccaag
     2521 gggatgagtc taaaccagca gcagaagcta ataagactga aaaagaagtc cagccagatg
     2581 tccctaaaaa tacagaaaaa acattaaaac caaaggaaat caaatttaat tcttgggaag
     2641 aattgttaaa atgggaacca ggtgctcgtg aagatgatgc tattaaccgc ggatctgttg
     2701 tcctcgcttc acgtcggaca ggtcatttag tcaatgaaaa agctagcaag gaagcaaaag
     2761 ttcaagcctt atcaaacacc aattctaaag caaaagacca tgcttctgtt ggtggagaag
     2821 agttcaaggc ctatgctttt gactattggc aatatctaga ttcaatggtc ttctgggaag
     2881 gtctcgtacc aactcctgac gttattgatg caggtcaccg taacggggtt cctgtatacg
     2941 gtacactctt cttcaactgg tctaatagta ttgcagatca agaaagattt gctgaagctt
     3001 tgaagcaaga cgcagatggt agcttcccaa ttgcccgtaa attggtagac atggccaagt
     3061 attatggcta tgatggctat ttcatcaacc aagaaacaac tggagatttg gttaaacctc
     3121 ttggagaaaa gatgcgccag tttatgctct atagcaagga atatgctgct aaggtaaacc
     3181 atccaatcaa gtattcttgg tacgatgcca tgacctataa ctatggacgt tatcatcaag
     3241 atggtttggg agaatacaac taccaattca tgcaaccaga aggagataag gttccggcag
     3301 ataacttctt tgctaacttt aactgggata aggctaaaaa tgattacact attgcaactg
     3361 ccaactggat tggtcgtaat ccttatgatg tatttgcagg tttggaattg caacagggtg
     3421 gttcctacaa gacaaaggtt aagtggaatg acattttaga cgaaaatggg aaattgcgcc
     3481 tttctcttgg tttatttgcc ccagatacca ttacaagttt aggaaaaact ggtgaagatt
     3541 atcataaaaa tgaagatatc ttctttacag gttatcaagg agaccctact ggccaaaaac
     3601 caggtgacaa agattggtat ggtattgcta acctagttgc ggaccgtacg ccagcggtag
     3661 gtaatacttt tactacttct tttaatacag gtcatggtaa aaaatggttc gtagatggta
     3721 aggtttctaa ggattctgag tggaattatc gttcagtatc aggtgttctt ccaacatggc
     3781 gctggtggca gacttcaaca ggggaaaaac ttcgtgcaga atatgatttt acagatgcct
     3841 ataatggcgg aaattccctt aaattctctg gtgatgtagc cggtaagaca gatcaggatg
     3901 tgagacttta ttctactaag ttagaagtaa ctgagaagac caaacttcgt gttgcccaca
     3961 agggaggaaa aggttctaaa gtttatatgg cattctctac aactccagac tacaaattcg
     4021 atgatgcaga tgcatggaaa gagctaaccc tttctgacaa ctggacaaat gaagaatttg
     4081 atctcagctc actagcaggt aaaaccatct atgcagtcaa actatttttc gagcatgaag
     4141 gtgctgtaaa agattatcag tttaacctag gacaattaac tatctcggac aatcaccaag
     4201 agccacaatc gccgacaagc ttttctgtag tgaaacaatc tcttaaaaat gcccaagaag
     4261 cggaagcagt tgtgcaattt aaaggcaaca aggatgcaga tttctatgaa gtttatgaaa
     4321 aagatggaga cagctggaaa ttactaactg gctcatcttc tacaactatt tatctaccaa
     4381 aagttagccg ctcagcaagt gctcagggta caactcaaga actgaaggtt gtagcagtcg
     4441 gtaaaaatgg agttcgttca gaagctgcaa ccacaacctt tgattggggt atgactgtaa
     4501 aagataccag cctaccaaaa ccactagctg aaaatatcgt tccaggtgca acagttattg
     4561 atagtacttt ccctaagact gaaggtggag aaggtattga aggtatgttg aacggtacca
     4621 ttactagctt gtcagataaa tggtcttcag ctcagttgag tggtagtgtg gatattcgtt
     4681 tgaccaagcc acgtaccgtt gttagatggg tcatggatca tgcaggggct ggtggtgagt
     4741 ctgttaacga tggcttgatg aacactaaag actttgacct ttattataaa gatgcagatg
     4801 gtgagtggaa gctagctaag gaagtccgtg gtaacaaagc acacgtgaca gatatcactc
     4861 ttgataaacc aatcactgct caagactggc gcttgaatgt tgtcacttct gacaatggaa
     4921 ctccatggaa ggctattcgt atctataact ggaaaatgta tgaaaagctt gatactgaga
     4981 gtgtcaatat tccgatggcc aaggctgcag cccgttctct aggcaataac aaggtacaag
     5041 ttggctttgc agatgtaccg gctggagcaa ctattaccgt ttatgataat ccaaattctc
     5101 aaactccgct cgcaaccttg aagagcgaag ttggaggaga cctagcaagt gcaccattgg
     5161 atttgacaaa tcaatctggt cttctttatt atcgtaccca gttgccaggc aaggaaatta
     5221 gtaatgtcct agcagtttcc gttccaaaag atgacagaag aatcaagtca gtcagcctag
     5281 aaacaggacc taagaaaaca agctacgccg aaggggagga tttggacctt agaggtggtg
     5341 ttcttcgagt tcagtatgaa ggaggaactg aggacgaact cattcgccta actcacgcag
     5401 gtgtatcagt atcaggtttt gatacgcatc ataagggaga acagaatctt actctccaat
     5461 atttgggaca accagtaaat gctaatttgt cagtgactgt cactggccaa gatgaagcaa
     5521 gtccgaaaac tattttggga attgaagtaa gtcaggaacc gaaaaaagat tacctagttg
     5581 gtgatagctt agacttgtct gaaggacgct ttgcagtggc ttatagcaat gacaccatgg
     5641 aagaacattc ctttactgat gagggagttg aaatttctgg ttacgatgct caaaagactg
     5701 gtcgtcaaac cttgacgctt cattaccaag gccatgaagt tagctttgat gttttggtat
     5761 ctccaaaagc agcattgaac gatgagtacc tcaaacaaaa attagcagaa gttgaagctg
     5821 ctaagaacaa ggtggtctat aactttgctt catcagaagt aaaagaagcc ttcttgaaag
     5881 caattgaagc ggccgaacaa gtgttgaaag accatgaaac tagcacccaa gatcaagtca
     5941 atgaccgact taataaattg acagaagctc ataaagctct gaatggtcaa gagaaattta
     6001 aggaagaaaa gacagagctt gatcgcttaa caggtgaggt tcaagaactc ttggctgcca
     6061 aaccaaacca tccttcaggt tctgccctag ctccgcttct tgagaaaaac aaggccttgg
     6121 ttgaaaaagt agatttgagt ccagaagagc ttgcaacagc gaaacagagt ctaaaagatc
     6181 tggttgcttt attgaaagaa gacaagccag cagtcttttc tgatagtaaa acaggtgttg
     6241 aagtacactt ctcaaataaa gagaagactg tcatcaaggg tttgaaagta gagcgtgttc
     6301 aagcaagtgc tgaagagaag aaatactttg ctggagaaga tgctcatgtc tttgaaatag
     6361 aaggtttgga tgaaaaaggt caagatgttg atctctctta cgcttctatt gtgaaaatcc
     6421 caattgaaaa agataagaaa gttaagaaag tatttttctt acctgaaggc aaagaggcag
     6481 tagaattggc ttttgaacaa acggatagtc atgttatctt tacagcacca cactttactc
     6541 attatgcctt tgtttatgaa tctgctgaaa aaccacaacc tgctaaacca gcaccacaaa
     6601 acaaagtcct tccaaaacct acttatcaac cggcttctga tcaacaaaag gctcctaaat
     6661 tggaagttca agaggaaaag gttgcctttc atcgtcaaga gcatgaaaat gctgagatgc
     6721 tagttgggga acaacgagtc atcatacagg gacgagatgg actgttaaga catgtctttg
     6781 aagttgatga aaacggtcag cgtcgtcttc gttcaacaga agtcatccaa gaagcgattc
     6841 cagaaattgt tgaaattgga acaaaagtaa aaacagtacc agcagtagta gctacacagg
     6901 aaaaaccagc tcaaaataca gcagttaaat cagaagaagc aagcaaacaa ttgccaaata
     6961 caggaacagc tgatgctaat gaagccctaa tagcaggctt agccagcctc ggtcttgcta
     7021 gtttagcctt gaccttgaga cggaaaagag aagataaaga ttaaatatcg aaaaatcttg
     7081 tgaaatcttt ccttatattt ccaaagtgtg atataatagt tttgaataaa ataaataaag
     7141 gagtttttgt aacatggcaa aacttactgt taaagacgtt gacttgaaag gtaaaaaagt
     7201 cctcgttcgt gttgacttca acgtaccatt gaaagatggc gtaatcacta acgataaccg
     7261 tatcacagca gctcttccaa ctattaagta catcatcgaa caaggtggac gtgcaattct
     7321 tttctctcac cttggacgtg tgaaagaaga agctgataaa gctggcaaat cacttgctcc
     7381 tgtagcagct gacttggcag caaaacttgg tcaagatgtt gttttcccag gtgtcactcg
     7441 tggtgctgaa ttggaagcgg caatcaacgc tcttgaagat ggacaagttc tcttggttga
     7501 aaacactcgt tacgaagatg ttgacggcaa gaaagaatct aaaaacgatc ctgaacttgg
     7561 taaatactgg gcatcacttg gagatggtat cttcgtaaac gatgcattcg gtacagctca
     7621 ccgtgcacac gcatctaacg ttggtatctc agcaaacgtt gaaaaagcag ttgctggttt
     7681 ccttcttgaa aacgaaattg cctacatcca agaagcagtt gaaactccag aacgtccatt
     7741 cgtggctatc cttggtggtt caaaagtttc agacaagatc ggtgttatcg aaaacttgct
     7801 tgaaaaagct gataacgtcc ttatcggtgg tgggatgact tacacattct acaaagcaca
     7861 aggtatcgaa atcggtaact cacttgtaga agaagacaaa ttggatgttg cgaaagctct
     7921 tcttgaaaaa gcaaatggta aattgatctt gccagttgac tcaaaagaag ctaacgcatt
     7981 tgctggttac actgaagtgc gtgacactga aggtgaagca gtttctgaag gcttccttgg
     8041 tcttgacatc ggtccaaaat ctatcgccaa atttgacgaa gctttgactg gtgccaaaac
     8101 agttgtatgg aacggaccta tgggtgtatt tgaaaaccca gatttccaag ctggtacaat
     8161 cggtgtgatg gacgctatcg tgaaacaacc aggagttaaa tcaatcatcg gtggtggtga
     8221 ctcagctgcc gcagcgatta accttggccg tgcagacaag ttctcatgga ttagtacggg
     8281 tggtggagca tcaatggaac ttcttgaagg taaggttctt ccaggacttg cagccttgac
     8341 agaaaaataa gattttataa ataaatcaaa gaagagaggg atgaaagttc ctcttttctt
     8401 ttgcttaaaa taaaaacgct tcctctcaac tattactcat aaaaatcacc gatttatgat
     8461 aaaatggaaa tagaaagttg agattatgag ttattttaaa aaatataaat tcgataaatc
     8521 ccagttcaaa cttggtatgc gaacctttaa aacaggtatt gctgtttttc tagttctctt
     8581 gattttttgc ttttttggct ggaaaggtct tcaaattggt gctttgacag ccgtttttag
     8641 cctgagggag agttttgatg agagtgttca ttttgggact tcgcgtattc taggaaatag
     8701 tatcggtgga ctctatgcct tggtcttctt cttattaaat acctttttcc acgaagcctt
     8761 ttgggtgacc ttggtagttg ttccaatctg caccatgtta accattatga caaatgtagc
     8821 aatgaataac aaagcagggg ttattggtgg tgtagcagct atgttaatca ttaccctatc
     8881 aattccaagt ggtgagacaa tttcgtacgt gtttgtgcgt gtatcagaaa cgtttatggg
     8941 agtttttgtc gcaattatcg taaattacga tattgatcgt attcgtctct ttttagagaa
     9001 aaaagaaaaa taatgttaca ttttataaca ttatcaattg acgtttgtct ttttttagac
     9061 tataatagac agaaagaagg aaattgtaaa tgaaggaaaa agaatttcgc cgaaatatgg
     9121 ctgtttttcc tatcggcagt gttatgaagt tgaccgatct atcggcgcgt cagattcgtt
     9181 attatgaaga tcaagagttg atcaagcccg atcgaaacga aggaaatcgt cgcatgtatt
     9241 ccttgaatga catggatcgt ctgcttgaaa tcaaagatta tatctctgaa ggttataata
     9301 tcgctgccat taagaaaaaa tatgctgaac gtgaagcgaa atccaagaaa gcggttagtc
     9361 agactgaagt acgtcgtgca cttcacaatg aactcctcca acaggggcgt tttgcttcag
     9421 tacagtcacc ttttggtcgc ggttaggcaa ccgcaagtag tcatagatta aggagaaaac
     9481 ttatgccaat cacagctgca gatattcgtc gtgaagtcaa ggaaaaaaat gttaccttta
     9541 ttcgtcttat gttctcagat attttgggaa ccatgaaaaa cgtcgaaatt cctgctacag
     9601 atgaacagtt agataaggtc ttgtcgaaca aggttatgtt tgatggatct tctattgaag
     9661 gttttgtacg tatcaatgag tcggatatgt acttgtaccc ggacttggat acatggacag
     9721 tcttcccttg gggagatgaa aatggaagtg ttgcaggtct gatctgtgat gtttatacaa
     9781 cagaaggtga accatttgcg ggtgaccctc gtggtaattt gaaacgagct cttcgtcaca
     9841 tggaagaagt tggattcaaa tccttcaacc ttggtccaga gccagaattc ttcctattta
     9901 agttggatga aaatggggac ccaacacttg aagtgaatga caagggtggc tactttgatt
     9961 tggcacctac tgaccttgcg gacaacacac gtcgtgagat tgtgaatgtc ttgaccaaaa
    10021 tgggatttga agtagaagcg agtcaccacg aggttgcggt tggacagcat gagattgact
    10081 ttaagtacga tgaagttctc cgtgcttgtg ataagattca aatctttaaa cttgttgtta
    10141 aaaccattgc tcgcaaacac ggactttacg caacatttat ggcgaagcca aaatttggta
    10201 ttgctggctc aggtatgcac tgtaatatgt ccttgtttga tgcagaagga aataacgcct
    10261 tctttgatcc aaatgatcca aaaggaatgc agttgtcaga aacagcttac catttcctag
    10321 gcggtttgat caagcatgct tacaactata ctgccatcat gaacccaaca gttaactcat
    10381 acaaacgttt ggttccaggt tatgaagcgc ctgtttacat tgcttgggct ggtcgtaacc
    10441 gttcgccact tgtgcgcgta cctgcttcac gtggtatggg aactcgtctt gagttgcgtt
    10501 cagtggatcc aatggcgaac ccttacattg ctatggctgt tcttttggaa gttggtttgt
    10561 atggtattga aaataaaatc gaagcaccag ctcctatcga agaaaatatc tacatcatga
    10621 cagcagaaga gcgcaaggaa gctggtatta cagaccttcc atcaactctt cacaacgctt
    10681 tgaaagcttt gacagaagat gaagtggtta aagctgctct cggagatcac atctacacta
    10741 gcttccttga agccaaacga atcgaatggg caagttatgc aaccttcgtt tcacaatggg
    10801 aaattgataa ttatttagac ctttactaat atagaagaaa gattgcctgt gggtaaacag
    10861 tcacacagca gtctaagcca tcaaatacct ataaccctta aaatagcgat ttcggtcgct
    10921 atttattttt cgaaaaatcc tcttgactct tttgcgaatt agatttatca tcagacgtgt
    10981 agaagaaaat caaggagtca ctatggaaaa attcaatttc aaaaacaata tcgggcaaga
    11041 aaacaagtta cttcaaatcg aaatctacaa gtttactaac ttttgcaagc ttcaaaatta
    11101 cacatctgta aatatttttt cgaaagatat atttgaagcc atagtaaatt gagactagaa
    11161 tagtacacta catctgctaa aaatttctag aaattaattt aactttccta atcgatttgt
    11221 ttacatctta tttcaatcta ctatattatc tcaataaatg atgatggcga ctgttttgtt
    11281 tgtgcttgtc gatttttgaa tcctgatcga gcggaagaat atttctgccg aggttgtcaa
    11341 ggggaaaatc ctgaagatat tgaattttat gatgaacaat tacaggcaga aaaggtggag
    11401 gctttgaata ttcgattgga agtaaaaaat tgaattatct acaatctcat caacaataaa
    11461 cctatttcaa ccccattatc tataggcgta tttttacgcc tttttatata cttgaagcac
    11521 ataagaaaca ttatgggaag tttgctgatg gaagtactca agaaattgat gttccttatg
    11581 atattcctga tacttgggag tgggtgaggt tttctacatt ggttgaaatt gtcagaggtg
    11641 gctctccacg accaatcaaa gattatctta cttctgaagt agatggaata aattggataa
    11701 aaataggtga tactgaaaag ggtgaaaagt atataaataa tgttaaagaa aaaatcaaaa
    11761 aatcagggct taacaaaact agatttgtaa aaaaaggtac atttttgtta actaattcta
    11821 tgagttttgg tagaccttat attttgaatg ttgatggtgc aatacacgat ggatggttgg
    11881 ctatttcgaa ctatgaaaac tcattaaata aagattacct attctatatt ctttcatcaa
    11941 atgtagttta ttctcaattt ctatctctaa ttagtggagc tgttgtgaaa aacttgaata
    12001 gtgataaagt tgcttctatt cttatccctc tccccccact atccgaacaa caacgaatag
    12061 tagaagcaat cgaatcagct ttagaaaaag tagatgaata tgctgaaagt tataatagac
    12121 tagaacagct agataaagaa tttccagata aactaaaaaa atctattctt caatatgcta
    12181 tgcaaggaaa attagttgaa caagacccaa atgatgaatc agtcgaagtt ttacttgaaa
    12241 aaatacgagc agaaaaacaa aaactctttg aagaaggcaa gattaaaaag aaagatttgg
    12301 acatttctat tgtttcccaa ggagatgata actcttatta tgggaacaaa gacgaaacat
    12361 cctcttatcc tatatatgaa atcccagaag catggagata tattaaattt gctagcctag
    12421 ttaacttcag aataggaaaa actcctccac gcagtgaagc tactttttgg ggaactgaaa
    12481 taccctgggt atctatatca gatatgccta tatctggtta tgtaactaat acgagagaat
    12541 ctatttctaa attagcatta aaatcaaaga aaatagacat ttcacctaaa ggaactttat
    12601 taatgagttt taaattatct attggaaaag ttgccatatt ggatattcct gccactcata
    12661 atgaagccat tatatcgata ttcccctatg ctaataaaga aaatattatc agagattact
    12721 taatgatatt tttgccactt atctctactt taggtgattc aaaagatgct atcaaaggga
    12781 aaacattaaa tagtaccagt atctccgaat tattaatccc tatttctaat catgaagaga
    12841 tgaaaagaat catttccaaa gttgatttac tttttcaaaa agtttctcaa ctttttgagt
    12901 aataagttcc tgttcctcaa aaggagctaa cggaattaat agctcgctta gtgtagtttt
    12961 aggaatatta tataaagctt gacctgatag tttagttatt gctttcaatt gtttataaaa
    13021 taacggagag gacaagttaa ataatagaaa ttttgaaata atctctgaac tttcgaatgg
    13081 tgttaattgg aaaataaatc caccagccac aacaccatca tagtctttat cgattcttgc
    13141 aaactttcca atatgttcta aagaggttga tacaggtgtt attagctgat tatgttttaa
    13201 ataaacttgc tcagaggaga tgaattgtgt atcaatgtag taatcattat ccaacagaga
    13261 aaattctaaa ggcttaatat taccaccacg tataattcta acacctttat tattaatgct
    13321 taaatcgccc ttcttgtaag aaagacctgt attcattgaa aaaatatctt ttatttttat
    13381 aacaacccaa ttcataggta t
//
LOCUS       DAVLDI010000059        13265 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLDI010000059 DAVLDI010000000
VERSION     DAVLDI010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13265
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.059"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            115..675
                     /locus_tag="VXD01_001840"
     CDS             115..675
                     /locus_tag="VXD01_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0602186.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            676..2061
                     /locus_tag="VXD01_001841"
     CDS             676..2061
                     /locus_tag="VXD01_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602187.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSNGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDYMVELRDGKLREVFQIPS
                     YEMTQVASKEVAASPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            2063..2713
                     /locus_tag="VXD01_001842"
     CDS             2063..2713
                     /locus_tag="VXD01_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV0602188.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            2724..3416
                     /gene="tenA"
                     /locus_tag="VXD01_001843"
     CDS             2724..3416
                     /gene="tenA"
                     /locus_tag="VXD01_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV0602189.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            3421..3945
                     /gene="thiW"
                     /locus_tag="VXD01_001844"
     CDS             3421..3945
                     /gene="thiW"
                     /locus_tag="VXD01_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV0602190.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            3945..4748
                     /locus_tag="VXD01_001845"
     CDS             3945..4748
                     /locus_tag="VXD01_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0602191.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     SREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            4741..5373
                     /locus_tag="VXD01_001846"
     CDS             4741..5373
                     /locus_tag="VXD01_001846"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0602192.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(5582..6373)
                     /gene="thiD"
                     /locus_tag="VXD01_001847"
     CDS             complement(5582..6373)
                     /gene="thiD"
                     /locus_tag="VXD01_001847"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0602193.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPESVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(6457..6555)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6779..7174
                     /locus_tag="VXD01_001848"
     CDS             6779..7174
                     /locus_tag="VXD01_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV0602194.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            7185..7556
                     /locus_tag="VXD01_001849"
     CDS             7185..7556
                     /locus_tag="VXD01_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV0602195.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            7566..9809
                     /locus_tag="VXD01_001850"
     CDS             7566..9809
                     /locus_tag="VXD01_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV0602196.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QAAGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            10016..11791
                     /gene="spxB"
                     /locus_tag="VXD01_001851"
     CDS             10016..11791
                     /gene="spxB"
                     /locus_tag="VXD01_001851"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV0602197.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            11902..12249
                     /locus_tag="VXD01_001852"
     CDS             11902..12249
                     /locus_tag="VXD01_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV0602198.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEIEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(12366..13265)
                     /locus_tag="VXD01_001853"
                     /pseudo
     CDS             complement(12366..13265)
                     /locus_tag="VXD01_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         3779 a         2576 c         2918 g         3992 t
ORIGIN      
        1 tttctagaaa tattttagtg ttcttgtgta ctgttctaaa ttcagtctgc tatacaaagt
       61 atttaggtct gtcttcttga gtgccccact tttctttaaa aaaaggagtt ttttatgttg
      121 aaaaaatggc agttaaaaga tgttatcttg cttgctttct tgtctatctt ttttggtggg
      181 gttttcgttg gttcaggata tgtgtataat attctcagtc tactcttaac acctcttggt
      241 ttgcaggcct ttgccaatga aatcctcttc ggtctctggt gtatggctgc gcccattgct
      301 gccatctttg ttccgagagt cggaagtgca acgattggag aagtgctagc tgcgcttgct
      361 gaagtccttt atggtagcca atttggtcta ggagctcttt tgtctggctt ggttcaaggt
      421 ttgggaagtg aatttggttt tatcgtaact aagaatcgct atgaaagttg gctctctcta
      481 actgctaata gtattgggat tacgcttgtt agctttgtct atgaatacat taagttaggc
      541 tactacgcct tttcccttcc gtttgtcctt tccttgcttg tggtacgttt tatttctgtt
      601 tatttcttct gtaccatctt ggttcgtgcc attgtcaaac tctatcatca gtttgcaact
      661 ggaggaaaag catagatggg tctggaacta cgagcgattc agtccccaat cttctctgag
      721 ccgtttgatt ttacttttca tgcgcaagcc tttaccttgt tagttgggag caatggttca
      781 ggaaaatcca gcctctttca aatgattgcc caagtcagtt ctcttcccta tagtggtcaa
      841 gtcctgatag atgggagcga ggtcagtcag ctttctatca tcgcacgtgt ccagaaggtt
      901 ggcattctct tgcaaaatcc caatcatcaa tttaccatgg agaacttgtt tgaggagctg
      961 attttcacct tggagaatat cggctatcac cttcaggaaa ttgattctaa aatagcagag
     1021 gttgtccagc aatgtcgttg cgaggcaatc ttacaccgtc ccattcatca cctatcaggt
     1081 ggggaaaagc aaaaagcagc gctggctgtc ctctttgcca tgaatcctag ggtctatctc
     1141 ttggatgagc ccttcgcttc cattgaccgc aagagtagaa tcgagatatt ggagattcta
     1201 aaagagttgg ctcttgatgg gaagacagtc attttgtgcg accatgattt atctgactat
     1261 aaagcctata tcgactatat ggttgagcta agagacggaa aactaaggga agtgtttcaa
     1321 atcccttcct atgagatgac acaggttgct tcaaaggaag ttgctgctag cccggaatta
     1381 ttccatatga accgtgtgac tggtgagctt ggtaatcgcc ccctcttttc aattgctgat
     1441 ttcacattct atcaagggat ttcctgtatc ctgggtgaca atggtgtcgg gaaatcaacc
     1501 ctctttcggt ctattcttca atttcaaaag tataaggggc gcattgcatg gaaggggaca
     1561 gtcctgaaaa agaaaaagag tttgtaccgt gatctgacgg gtgttgttca ggaagctgag
     1621 aagcagttta tccgagtcag tctgcgagag gagcttcaat tagatggacc tgattctgaa
     1681 agaaatcagc ggatttttca agctttacga tattttgatt tggagcaggc agtcgataag
     1741 agtccctatc aattaagtgg tggtcagcaa aaaattcttc agctcctgac catcttgacc
     1801 agtaaggctt ccgtgatctt gctagatgaa ccttttgcag gtttggatga tagagcctgc
     1861 cattattttt gcaagtggat tgtggaggag aggaaccaag gaagaagttt tctgctcatt
     1921 agtcatcgtt tagacccttt gatttctgtg gttgattatt ggattgagat gactagtcag
     1981 ggtcttcggc atgtgaaaga agtgaccatt accaaaccac ttacatctca gagtagcaat
     2041 acccaagggg aggtgagata gtatggtcaa agtagcaacc cagacaccga ttatcagtct
     2101 cttcttgctg attttatcct tggaaacatc tttcattcct tcgattgctc tgaatctttc
     2161 ggtagtcgca ttttgtattc tctttatgct ctattaccgt cgatttaaaa tgttagcttg
     2221 gatgatcata cttgccattt taccatcttt tgccaactac tgggcagttc agttacacgg
     2281 agatgcttca caggcagtca tgcttggaac gagggctttt gtgacagttt gtatcggcct
     2341 tgtctttgtt tcctctattt cactaaaaga gcttctcttg tacttggctc aaaaggggct
     2401 atcacgctct tggtcctatg ccttgattgt ggtattcaat tcctttcctc tcattcagca
     2461 agaaatcaag tccctcaaag aagcttgcct attacgtggt caagaactac atttttggtc
     2521 gcccttgatt tacagtaagg ttctgatgac agtctttagg tggcgccatc tttacctgag
     2581 agctctatct gctcacggat atgacgaaca tgcacagttg aagaatagct atcggacttt
     2641 ttatattcct aaaaaaacaa aattaatcta cctgcttttc tttttattgc ttcaaaccag
     2701 tctattttta taaaggagtt attatggaat ttacagatat tgcgatggaa ttatccaaga
     2761 aagcttggca ggcttccttt catcatccct ttattttaca attacaagag gggaatttag
     2821 aacctgccat tttccgctat tacctgattc aggatgccta ctatctgaag gctttctcag
     2881 aaatctatca tctgttggct gataagactt caaaccaaga gatgaaaaga ctcttgaaac
     2941 aaaatgctca gggtttagtg gagggtgagt tatttattcg ccaacaattt ttcaaggaat
     3001 tggaaatcaa cgaccaggaa atggagcaac atccaatcgc tccaacctgt tatcattaca
     3061 tttctcatat ttataggcaa tttgcagaac cgaacttagc catagctttt gcaagcttgc
     3121 ttccttgtcc ttggttatac catgatatag gcaaatcact taatcttaaa ccatcaccaa
     3181 atcctctcta tcaacaatgg attgaaactt atattacgga tgagttagag caacagatca
     3241 gagaggaggg agcactggtc aatcagctct atcgagaaag tgatgagaca gataagcaaa
     3301 aaatgctaga tgccttccac atcagtgttc atatggaagc caagttttgg gagatggctt
     3361 accaacacca gacatggaag agcgatttac agtctttaga aaaaggagaa gaatagaaac
     3421 atgagaaagc accaactaca agttcacaaa ttgaccattt tatctatgat gattgccctt
     3481 gatgtagtcc ttacacctat ctttcggatt gagggaatgg caccgatgtc cagtgtagtc
     3541 aatattctag cgggaatcat gatgggacct gtttatgcct tggctatggc tacagtgaca
     3601 gcctttatcc gtatgacgac tcaagggatt ccgcctttag ctctcacagg agcgactttt
     3661 ggagcccttc tagcaggtct cttttataag tacggtcgaa aattttactt ttctgccttg
     3721 ggagaaattg tgggaacagg tattattggt tctattgttt cctatcctgt tatggtactc
     3781 tttacaggat cagctgctaa gcttagctgg tttatctaca cgcctcgatt tttcggagca
     3841 accttgattg gtacagcgat ttcctttatt gcctttcgat ttttaatcaa gcaggaattc
     3901 tttaaaaaag tgcagggata tttctttagt gaaaggatag actgatgcag gaatttacaa
     3961 atccctttcc tataggctct agttccctca ttcactgtat gaccaatgag atttcttgtg
     4021 agatgctggc aaatgggatt ttggctctgg gatgcaaacc tgtcatggca gatgattccc
     4081 gtgaagttct tgattttact aagcaaagtc aggctctctt catcaattta ggtcatttgt
     4141 cagctgagaa ggagaaagca atccgcatgg cagcttcgta tgcaaaccaa tcttctctcc
     4201 cgatggtagt agatgcggtt ggcgtaacga cttcatccat tcgtaagagc ttagttaaag
     4261 accttttaga ctatagacct acggtcctta aaggaaacat gtcagaaatt cgaagtcttg
     4321 ttggattaaa gcaccacggc gttggggtcg atgcgagtgc taaagatcaa gaaacggagg
     4381 atttgcttca agtcttgaaa gactggtgtc agacctatcc tggtatgtca ttcttagtta
     4441 ctggccccaa ggacctcatc gtttcgaaaa atcaggtcgc tgtactggag aatggctgta
     4501 ctgaattaga ctggataaca gggacaggag atttggttgg agccttaaca gccgtttttc
     4561 tcagccaagg aaagactggt tttgaagctt cttgcttagc agtctcttat ctcaatatcg
     4621 ctgctgagaa aatagttgtt caaggaatgg gattggaaga atttcgttac caagtactca
     4681 atcagctttc gctcctaaga agagatgaaa attggctaga taccatcaaa ggagaggttt
     4741 atgaatagag aagcacttag actatatctg gtaaccaatc gctatcaaga ttccgtggaa
     4801 agctttcttg caaaagttga gacggcctgc cgttcagggg ttaccatagt ccaattgcga
     4861 gaaaaaaatc tcacaaccaa tcaatattat caactggcaa aacaagtcaa ggaaataaca
     4921 gatgcttatc aggtaccctt gataatcgat gatcggttgg atgtttgtct tgcggttgat
     4981 gctgctggtc tgcatattgg agatgacgaa ctcccagttt cggttgcccg acaagtcttg
     5041 ggtcctgaaa aaatcctcgg tgtcaccgct aaaacggtta aaagagctct ggaagcggag
     5101 aaatcaggtg cagattactt ggggacagga gccatttttc cgacaaccac caaggaaaat
     5161 gcacccatca ccctgatttc aaccttgaaa acaatttgcc aaacggttgc cattccaata
     5221 gttgctattg gcggcttgac ttcggagaat attgatcagc ttatgggcac tggcatagct
     5281 ggtgtagctg ttgtacgtga tttgatgcaa gcagaagata ttgaggcaaa aacgcaagcc
     5341 tttttaacaa agttgcatga cattctttcc taattaatac tcaatgaaaa tcaaagagta
     5401 aactagaaag ctagtcgcag gttgctcaaa gtactgcctt gaggttttag ataagactga
     5461 cgaagtcagc tcaaaacagt gttttgaagt tgcagatgga agctgacgta gtttgaagag
     5521 attttcgaag agtataaaaa ctctctaatt cccttaaagt gggaactaga gagttttttt
     5581 cttaatcttt aaaagttgta tggttgactg gaccagaacc atgaccgagt tgaggggcat
     5641 cttgaatagc ttttgtgata aaggccttgg ccttatcaac tgcctggtaa agactcttgc
     5701 ccttggctag ttcagcagta atcactgcag caaaggtaca tccagtacca tgggtgtgac
     5761 aggtttgaat tcgtgggctt tcccagacaa attgttcatt cttggtaaag aggaaatctt
     5821 tagcaccacc tttgagatgt ccgcctttga taaccacaga ctcaggacca aattctttta
     5881 aaatcaggcg accagcacgc tgcatgcctt cggggtcatg gattgaaaaa ccaacaatct
     5941 cttctgcttc aggaagattt ggcgtaataa tagttgctag aggtagtaag tttgttttga
     6001 gatagtctct agcacttgag tcaatcaagg catctccact tgtagcaacc ataacaggat
     6061 caaggacata gggacaatcc agttttttaa gatagggttg gatgatttcc atgatttcag
     6121 tagtagccaa cattccagtt tttacagcct gaggtggaat atcagaaaag acactctcca
     6181 attgggcttt caacatttga ggagaaacat gctcgattag ctgaacacct ctggtatttt
     6241 gagcgacaag actggttaca acagccattc catagacatc tctcgcttgg aatgacttta
     6301 aatctgccat aatgccagca ccaccactag ggtcagtccc tgcaatggtc aaagcaacgg
     6361 gtaaataagt catctaaaac ctcccaacca actgaagttt gtattcttaa gaacaagcta
     6421 gtctgtttta gaaaggcaat agaagactgc tagtccccat tatcatttcc acttccatca
     6481 gctagtatta cctagattga gtcagaggga tctaacagtc gttaatctca gctttacgca
     6541 cccctagtgg ttgttttctt ttttctttag tatagcatat ttttattgtt tatatagtaa
     6601 tatttgactg caaatcgttt ttcaaatgat taaaattcta tttttcgaag aaaatattat
     6661 ttctataatt gacaaatgta gattttaaga gtatactgat gagtgtaatt gacaaatgta
     6721 gattttaaga gtatactgat gagtgtaatt gacaaatgta gattttggag gtatggtaat
     6781 gcagatttca gatgcagaat ggcaggtcat gaagattatt tggatgcagg gggagcagac
     6841 cagtacagat ttgattaggg ttttggcaga gcggttcgac tggtccaagt caaccattca
     6901 aactcttttg gctcgtttgg ttgagaaaga gtgtctgact cggaaaaaag aaggcaagtt
     6961 ctttgtttat tcagcccttt taactctaga ccaaagtcgg gatttacttg tccaagatat
     7021 caaagacaag gtttgttccc gtaggattag gaatttgttg gctgacttga ttgtagaatg
     7081 tgaatttact cagactgact tggaagactt ggaagctgtg atttcagaga agaaatcaag
     7141 tgctgtaaca gaagtaagat gtaattgtat gtaaaggaga cgtcatgtta aatagtattg
     7201 taaccattat ttgtattgcc cttatcgcgt ttatcttgtt ttggtttttc aaaaagcctg
     7261 aaaaatctgg acaaaaagcc cagcaaaaaa acggatacca agagattcga gtggaagtca
     7321 tgggaggcta tactcctgag ttgattgtcc tcaagaaatc agtgccagcc cgcattgtct
     7381 ttgaccgcaa ggatccttca ccatgtctgg atcaaattgt ttttccagat tttggtgtac
     7441 atgcgaacct gccaatgggg gaagagtatg tagtggaaat cacgcctgaa caggctggag
     7501 agtttggctt tgcttgtggt atgaacatga tgcacggcaa gatgattgta gagtaggtgg
     7561 agactatgac agaaattgtg aaagcaagct tagaaaatgg cattcaaaaa atccgtatcc
     7621 gagctgaaaa aggctatcat ccagcccata tccagcttca aaagggaatt ccagctgaga
     7681 ttacctttca tcgtgctact ccttcaaact gttataagga aattctgttt gaagaagaag
     7741 gtatcttgga accaatcggc gtagatgagg agaaagtcat tcgttttaca cctcaagaat
     7801 tagggcgaca tgaattttct tgtggcatga agatgcaaaa gggaagctat atagtcgttg
     7861 agaagactcg aaaatctcta tctctcctgc aacgtttttg gattactagt atctttactg
     7921 tgcctcttgt gattctcatg attgggatgt tgacaggtag cattagtcat caagtcatgc
     7981 attggggaac ctttctagca acaacgccta ttatgttagt tgcaggtaag ccatatatcc
     8041 agagtgcttg ggccagtttt aaaaagcaca atgccaacat ggataccttg gttgcgctgg
     8101 gaactctagt ggcttatttc tatagcctag ttgctctctt tgctggtctc cctgtttact
     8161 tcgaaagtgc tggatttatc ctctttttcg ttcttttggg agcagttttt gaggaaaaaa
     8221 tgagaaaaaa tacgtcccaa gctgtggaga aattactgga cttgcaagct aaaaccgcag
     8281 aagtcttgag tgatgatagt tatgtccaag ttcctttgga acaagtcaag gtaggcgacc
     8341 tgattcgagt gcgtcccggt gaaaagattg ctgttgatgg tgtcgtagta gaaggtgtct
     8401 ctagtattga cgaatccatg gtgacaggtg agagtctgcc tgtggacaag acagttggag
     8461 atactgtcat tggctcaacc atcaatcata gtggaacgct tgtctttaga gcagaaaaag
     8521 ttggctcaga gactgttttg gctcagattg tggattttgt gaagaaagct cagacaagtc
     8581 gtgcgccgat tcaggacttg acggataaga tttcagggat ttttgtccca gtagttgtca
     8641 ttttaggaat catgaccttt tgggtttggt tcgtcttgct cagggatagt gtggtcgtgc
     8701 ttggagctag ctttgtgtcc tctcttctct acggagtggc ggttttgatt atcgcctgtc
     8761 cttgtgcctt gggacttgca acaccgacag cccttatggt ggggacagga cgtagtgcca
     8821 agatgggggt tctcctcaaa aatggaactg tcttacagga aatccagaaa gttcaaactc
     8881 ttgtctttga taagaccggg actttgacgg aagggaaacc tgtggtaaca gatatcatcg
     8941 gcgacgaagt agaagtgttt ggattggcag cctccttgga agatgcttct caacacccac
     9001 tggctgaggc tatcgttaag cgagcgagtg aagctggact tgagtttcaa actgttgaaa
     9061 attttcaggc cttgcacggg aaaggtgttt cagggcgaat caatggaaaa caagttttac
     9121 ttggaaatgc taaaatgctg gatggcatgg atatttctaa tacttatcaa gataaactag
     9181 aagaactaga aaaagaagct aagacagttg tgtttttagc tgttgacaat gaaatcaaag
     9241 gcttgcttgc tttgcaagat attcctaagg aaaatgctaa gctagccatc agtcagctaa
     9301 aaaaacgtgg tctccgaaca gtcatgctga caggagacaa tgctggtgtg gcgcgtgcta
     9361 ttgcagatca aatcggaatt gaagaggtca ttgcaggcgt cttgccagaa gaaaaagccc
     9421 atgaaatcca taaactgcaa gcggctggca aagtagcctt tgttggggac ggtatcaatg
     9481 acgctcctgc ccttagtgta gcagatgtgg gaattgctat gggtgctgga acagatatcg
     9541 ccatcgagtc agcagatttg gtgttgacaa ccaataatct tttaggagtg gttcgtgcct
     9601 ttgatatgag taagaaaacc tttcatcgaa ttctactcaa tcttttctgg gcttttatct
     9661 acaatgttgt cggaattccg attgcagcag gagtcttttc aggtgttgga ctggctctca
     9721 acccagaatt ggcaggtcta gccatggcct ttagttctgt atctgttctg accagttccc
     9781 ttctgttaaa ttttagtaaa atagactaaa agtaatgact agatttcttt gttataaaac
     9841 agaaatgaca acactttcaa aactgtatta gaatagagaa tagagagttt tgagcagatt
     9901 tttagaaaag tcagcataaa tatgatacag tggaatagta aaaatttgga gaacgtttcc
     9961 aattctatgt aatcgtattc tccaagttta aaaaaattga aggagagtta tcattatgac
    10021 tcaagggaaa attactgcat ctgcagcaat gcttaacgta ttgaaaacat ggggcgtaga
    10081 tacaatctac ggtatcccat caggaacact cagctcattg atggacgctt tggctgaaga
    10141 caaagatatc cgcttcttac aagttcgcca cgaagagaca ggtgctcttg cagcggttat
    10201 gcaagctaaa ttcggcggct caatcggggt tgcagttggt tcaggtggtc caggtgcgac
    10261 tcacttgatt aacggtgttt acgatgcagc tatggataac actccattcc tagcgatcct
    10321 tggatcacgt ccagttaacg aattgaacat ggatgctttc caagagctta accaaaaccc
    10381 aatgtacaac ggtatcgctg tttacaacaa acgtgtagct tacgctgagc aattgccaaa
    10441 agtaattgac gaagcctgcc gtgctgcagt ttctaaaaaa ggtccagctg ttgttgaaat
    10501 tccagtaaac ttcggtttcc aagaaatcga cgaaaactca tactacggtt caggttcata
    10561 cgaacgctca ttcatcgctc ctgctttgaa cgaagttgaa atcgacaaag ctgttgaaat
    10621 cttgaacaat gctgaacgcc cagttatcta tgctggattt ggtggtgtta aagctggtga
    10681 agtgattact gaattgtcac gtaaaatcaa agcaccaatc atcacaactg gtaaaaactt
    10741 tgaagctttc gaatggaact atgaaggttt gacaggttct gcttaccgtg ttggttggaa
    10801 accagccaac gaagtggtct ttgaagcaga cacagttctt ttccttggtt caaacttccc
    10861 atttgctgaa gtttacgaag cattcaagaa cactgaaaaa ttcatccaag tcgatatcga
    10921 cccttacaaa cttggtaaac gtcatgccct tgacgcttca atccttggtg atgctggtca
    10981 agcagctaaa gctatccttg acaaagtaaa cccagttgaa tcaactccat ggtggcgtgc
    11041 aaacgttaag aacaaccaaa actggcgtga ttacatgaac aaactcgaag gtaaaactga
    11101 gggtgaattg caattgtatc aagtttacaa tgcaatcaac aaacatgctg atcaagacgc
    11161 tatctactca atcgacgtag gtaacactac tcaaacatct actcgtcacc ttcacatgac
    11221 acctaagaac atgtggcgta catctccact ctttgcgaca atgggtattg cccttcctgg
    11281 tggtatcgct gctaagaaag acaatccaga tcgccaagta tggaacatca tgggtgacgg
    11341 agcattcaac atgtgctacc cagacgttat cacaaacgtt caatacgacc ttccagttat
    11401 caaccttgtc ttctcaaatg ctgagtacgg cttcatcaag aacaaatacg aagatacaaa
    11461 caaacacttg tttggtgtag atttcacaaa cgctgactac gctaaaattg cggaagctca
    11521 aggagctgtt ggattcacag ttgaccgtat cgaagacatc gatgcagttg ttgcagaagc
    11581 tgttaaattg aacaaagaag gtaaaactgt tgtcatcgat gctcgcatca ctcaacaccg
    11641 tccacttcca gtagaagtac ttgaattgga tccaaaactt cactcagaag aagctatcaa
    11701 agccttcaag gaaaaatacg aagcagaaga actcgtacca ttccgtctct tcttggaaga
    11761 agaaggattg caatcacgcg caattaaata attcctctcg ccgaaaatca aatatgaaac
    11821 ttgtagactt tattctttga ttttcataga gcagaacttt aaaagatcgg agcaatccgg
    11881 tctttttatg gaggagagta aatgaattta aatcaattag atattatcgt ttcaaatgtt
    11941 ccccaagtct gtgctgactt ggagcatatc ttggataaaa aggcagatta tgctgatgat
    12001 ggttttgctc agtttacgat tggtagtcac tgccttatgt tgtcacaaaa tcatttggtt
    12061 cctttggaaa actttcagtc aggaatcatt attcatatcg agattgagga tgtagaccag
    12121 aactacaaac ggttgaacga gcttggtata aaggttttac acggaccaac tgtaaccgat
    12181 tggggaacag agtccttatt agttcaagga cctgctggtc tagtgcttga tttttatcgt
    12241 atgaaatagg tcgcgtagtc atttgacgtt aaccttagct atttttaaaa tagaaattga
    12301 gaatatgaac tattgaaaga tcggagcaat ccggtctttt tatataaaga aattgcatat
    12361 aatactcatc tgctttcaaa aagcattcta gtccatctcc gattaacgat ggactttatc
    12421 acctccttct ccaatccttg tatgacatct tggagttgat tcatgacatc ttccaaagtt
    12481 cgaaaggctt tattcttaaa tccacgttta cgaatctctt tccacacttg ttcaatgggt
    12541 tcatctctgg tgtgtatgga ggaataaatg caaaaccaat attagtcgga atctttaagg
    12601 tacttgattt atgccatata gcattgtcta taacgagtaa aaaataatca tatggataag
    12661 cttgtgaaag ctcttctaaa aaggcgttca tccactcagt attacatcta ccagctatta
    12721 agaaaaatga ttcgcctgta tgggcatcaa cagctccata acaatagcga aattctcgta
    12781 tatagtgact atggacatgt ggacctactc ctattggaga ccaacaagat cccagtttac
    12841 tgattctacc gaaaccagct tcatcttggt acatcaagcg aaccttatga aaaggtctac
    12901 tggttttaaa gcgctttctt gtcttcttga attgagattt tatttttaga tgcgacaatg
    12961 gtttgagcgt ctgctttctt aggatgttct ggacgtggcg taatatttcg ccaaccatgg
    13021 cgcttcaaca gttgatagaa ggcatcacgt gtgtaggaac gacctaactc ctttttataa
    13081 gcctgaaata aggcatcaat tgtaacaaat tctcctgcct ctgtagcctt caaatggcga
    13141 gcaagaaagg ctttctcttc ctcaactgtc atatatgcat ggttacgacc accacgtgtt
    13201 tcttgaagga gagagtcgag tccgaactcc tcatattttt tacatttcgc caaatcgttg
    13261 tttga
//
LOCUS       DAVLDI010000060        13106 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLDI010000060 DAVLDI010000000
VERSION     DAVLDI010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13106
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.060"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(276..1442)
                     /locus_tag="VXD01_001854"
     CDS             complement(276..1442)
                     /locus_tag="VXD01_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0602199.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLKTEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFLASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(1455..2194)
                     /locus_tag="VXD01_001855"
                     /pseudo
     CDS             complement(1455..2194)
                     /locus_tag="VXD01_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            complement(2216..3040)
                     /locus_tag="VXD01_001856"
     CDS             complement(2216..3040)
                     /locus_tag="VXD01_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV0602200.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISHMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            complement(3177..4391)
                     /gene="thiI"
                     /locus_tag="VXD01_001857"
     CDS             complement(3177..4391)
                     /gene="thiI"
                     /locus_tag="VXD01_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV0602201.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYAQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(4400..5542)
                     /locus_tag="VXD01_001858"
     CDS             complement(4400..5542)
                     /locus_tag="VXD01_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV0602202.1"
                     /translation="MIYFDNSATTKPYPEALETYVQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFSPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIHQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            5680..6114
                     /locus_tag="VXD01_001859"
     CDS             5680..6114
                     /locus_tag="VXD01_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602203.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSPNKENKTSQEKTQQEETPKSSVKE
                     EKKEEQKTSTQDSSTPAPTPSKPATENEKQSNTPTSENKTNQ"
     gene            complement(6159..8384)
                     /locus_tag="VXD01_001860"
     CDS             complement(6159..8384)
                     /locus_tag="VXD01_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV0602204.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(8548..10500)
                     /locus_tag="VXD01_001861"
     CDS             complement(8548..10500)
                     /locus_tag="VXD01_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV0602205.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(10497..11408)
                     /gene="pfkB"
                     /locus_tag="VXD01_001862"
     CDS             complement(10497..11408)
                     /gene="pfkB"
                     /locus_tag="VXD01_001862"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV0602206.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            complement(11405..12145)
                     /locus_tag="VXD01_001863"
     CDS             complement(11405..12145)
                     /locus_tag="VXD01_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0602207.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12307..12394
                     /locus_tag="VXD01_001864"
     tRNA            12307..12394
                     /locus_tag="VXD01_001864"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12341..12343,aa:Ser,seq:gga)
     gene            complement(12589..12936)
                     /gene="ssrA"
                     /locus_tag="VXD01_001865"
     tmRNA           complement(12589..12936)
                     /gene="ssrA"
                     /locus_tag="VXD01_001865"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         3830 a         2958 c         2505 g         3813 t
ORIGIN      
        1 gctctttgat tttcattgag tattaataga ctggtttggt atcctgaaaa ctatatcgta
       61 taggtgtcgt catggatcct tttagctgat ttaaggatac gaaaacacaa tactatgact
      121 aaattgaaat gttaaaattc aatttctagc cacctaatcc tgcttcaaat agttatcgaa
      181 caagttttat gatagctacc ttgttaggat gctcttattt tttaccagac aaaacaaaag
      241 gattaaggga gtgaatttcc ttaatccgat agttcttatt cttgacgttg tccgaaatca
      301 gcaatcatct gatccatttc ttgtcgactc ggagttgtca gcatatacag gtaatctcct
      361 tgaagttccg cgaaggcagc tggcatgact tttttaacct tgaactgctg gctatatttg
      421 gcaagcaaat cctcttctga ataaacatag tgagcatttg cacggcgaga agtagccaaa
      481 caatactgag tttcaaagtc tgacgccagg aactcctctc ctgcgacaat agctgcatag
      541 ccacgataaa ggtccaagga atgagcaaag ttataaacat caatggtaaa accacctgca
      601 gggcggttat tgtactcgat ggtaatataa tcgtccccct cacggaagaa ctcaatatgg
      661 aaaaaccgtt ctttcatacc aaattctttg acaattgctt ccccatactt gcgcagttta
      721 ggatccatat ccttgagcac ataataagaa ttgtccatct tataaatcat gaggtcaagc
      781 ggtgtatagg cgtagtcaaa ggttgttgag aagacaatct ttccatcctt gtccacgagc
      841 ccgtcaaagg tacagatttc gctggaagtg acaaattttt caaagaaata aagggttgaa
      901 tggtcccatt cttgcttgaa gtgattgata tcgtcttctg tcttaagttt aaaggttgcg
      961 gctgctccca ctccattatc aggtttggca atcattggaa gaccgatttc tttcactgct
     1021 tgatcaacat ctgcttccgt cttgataaca gctccaggta ccacaggaac acctgctttt
     1081 ttgaaaagtt tcttcatttc agacttatat ttcgtctttt tgagatcctc tggtttggca
     1141 ccaaaaacat tgaattgttc tctgagtgtt gcgtctagct caagccagta ttcattgtga
     1201 gactcgatgc ggtcaattgg accatgttta taaaagagaa aagcaactgc acgtttgact
     1261 tcatctatgt tctcaagatt atcaacacga aaatactcgg tcaagctatt gcgcaagggc
     1321 tcatccaatt gctcgtaaga ctcttgacca attcccaaga ctgtgatgcc tttattagct
     1381 agttcgatgg taaactgttg aaagttttgt ggatagtagg gagaaataac aaggtaattc
     1441 ataggtaact ccttttataa atagagatta ccgaggaaat aaggcatttg tttacgccac
     1501 cattcccagt catgggcgac atcatgtccc cattcagcaa accaggctgg aatttgtttc
     1561 ttgtcaaagg cttctttgag cttgtaaaag gatggcaaac catcttgttc ccaggctcca
     1621 agccccgtac acagcacaat ctctgcctga cggtaacggt caataaacca gccgtcgttt
     1681 tggttccaaa tataatctac tggcgagttt tggtaaatag catcatcgtt gtagtaatca
     1741 ccgacaaaga aacgtgcgtc gtaaacacca ctgagagcaa tcactttggt aaagacatct
     1801 ggatgctgga ggaagaaatt gagtgcatga taggctccca tagagcaacc tgtcgtcatc
     1861 atgccatcaa accaacctgt cttgtgcttg ataaaagaat ggcctcctca atcacataac
     1921 attcgtaggc acggtgcatt tccgcttggt catgagcatt tttccaagta gccaaccagc
     1981 tctcactatc cacactagat agggtaaaga actagacaag gccttcctcg ataaaggaag
     2041 cacaggcatc aatcatgcca aaatcatagt attcgttgtg actaccacct gatgaagcaa
     2101 agaccacaac tggaatccca ccatgtccat aacggttaag gtacatttca cggttaggat
     2161 gaccactcca gtggctaaga tgttcaatat gcatttcgtt ttttcctttc ttaacttacc
     2221 atttttctgc aaaaaatctc agacaatctg gtagattttc tgaccaaggg atttcactat
     2281 ggatggcacc agactgaact tttagcacaa gattatccag atgtactccc cctgctatca
     2341 aatcatggta atagcaaagc gacgagtcga tataggcttg tttgatattg ccatccatca
     2401 aggtcttgtc tgtatcatct gcttcttctg ttcctacata gatgaagatg cgctggtcag
     2461 gcgatagttt ctggcactcg atatagcggt taaaggcttc ttggtggagc cagtttgcag
     2521 atgaaaaaac gcccaagcaa ccaatttggt cttggtattc caaaccgata aactgggtaa
     2581 tattgcctcc tagtgaggaa ccaatcatag ccgtatgctg gcagtctgct tttgtacgat
     2641 aggtctcatc gataaaaggc ttgaccacct ccatgacaaa ctcagcatac tccacaccct
     2701 taccaccaaa ctgctgctct gggataggag attcttggaa cttccaagcc gcatactcat
     2761 tcattcgccc cataccatca ttgtcaatag caacgacaat catgtgactg atatccggat
     2821 ttcgtttgat agctgggata atcttccatg aatatccaat gaaagactct ttgctataaa
     2881 aaacattttg cccgtcatga aagtatacaa caggatagga acggtctgta tctttctcat
     2941 aatctttagg aagaagaata cgtacacggc gctccttacc tgtataagga accttgagtt
     3001 tgtgttcttt catttttaga taaaagtagg attgattcat tgtcagaaaa ctctctatat
     3061 tcaaaatttt atatcattat atcatgaaaa tagaaaaaag ttagtttttt acctgttttt
     3121 agaaaaaaaa actaactttt tttactgatt ttcgctattc ttttggattt tctgaattag
     3181 agtagattat caatcaagtc atcaacttca tctttttcgg cttgaggtgt gatttcagta
     3241 atcatgattc cagccactgc tcgctcaacc aagccttcaa catccatacg cgcttcgtac
     3301 tgctccgcat tcttaatttt aggatttgtt tttggacgat ctggtgcaaa aatggtacaa
     3361 cagtcttcaa acggttggat tgaaatgtca aaggtatcga tttcctgggc gatgtcaatg
     3421 atttccaact tgtccatggt aaccacagga cgaatgatgg gagtgttggt aacagcattg
     3481 atagccttca tactttcaag ggtttggctg gctacttgac ctagactttc cccattgatg
     3541 ataaccaaac catttcgtac ctcacgaata cggtcagtaa tccgcatcat aaagcgacga
     3601 gttagagtca tcaaataagc ttctggcgct ttggctttga tttcctcttg aatctctgtg
     3661 aaaggcacct cgataaactg gatatttccg ccaaacttgg tcaatttacg tgtcaagtcc
     3721 tgcgctttct tgagggcacc aggactagta tatggtggac tagcaaagtg aactgcctcg
     3781 atatccaccc cacgcttaag agcaagataa cctgctacag gtgagtcaat ccctcctgac
     3841 aacatgagca tccctttacc tgaagttcca actggcaaac caccagcccc acgaatggtt
     3901 tcataagaaa gataggctgc ttcttcacga atctccacct gaagattgat gtcaggactt
     3961 ttcatttgaa cttgcacatt tggaatggct tcgaatacag cccctccaag tgtttggttg
     4021 agttcacgac tatcaagttc aaagttgtgg tcgctacgct tgctagaaat cttaaaggtc
     4081 ataccttcct tgtagatgtc ccgcataatc tcttggacag aagacttcaa aacttctaca
     4141 gatttttcaa ccttataaac aggagaaaag ttttgaattc caaaaacttg tttgagagat
     4201 tctgcaactg ctgtgtaatc agctccattg aggtaagcgt gggcacggtc gcgatctgct
     4261 gttaccttaa cttgggcata gatagacaaa acgtccgaaa tattattacg aagtttattg
     4321 atgaaacgca tacggttttt acccttggtt gacaactctc cgtagcgaat cataatttct
     4381 gaatactgca tgaatgctcc tatcttactt ttctagtttg attgtaaatc aattttaact
     4441 tggtcaaaaa ctgctcgacc tgactcatat cattttccaa gtctaggcta agacgcacag
     4501 ctgacttggc cttatctttg tccactccca tggcaatcaa ggtaccggct ggttttcctg
     4561 ccttagatga acaagctgag gttgttgaga tgaaaatatc atagtcttca aaggcgtgaa
     4621 cgatgacttc acctcgaaca cctttgattc caaaagtcag aatatgaggt gcaaagtctt
     4681 cctcatctga aaagacaaaa atatccggat agttcagaag agcttggtga atcactgcct
     4741 tcatctgccc agtcttgctc ctaaagatat ctagcttttc catagataaa cggagagcct
     4801 tggctgtcgc tgcaatccct gccacatttt cagttgtcga acgataatct cgctcctggc
     4861 caccacctgt aagaagaggt gtaatcttct tgccagattt gatatagaca aagccaacac
     4921 cacggacacc atgaaattta tgactcgaga aggtcgcgca atccacccgt tctgtcagat
     4981 acttttcagt cggaattttg gcaagcgcct gaaccgcatc aacgtggaag gaaatagtcg
     5041 gcttgtctgc caagaattct gaaatagcct caataggttg gatagagccg atttcattgt
     5101 tcacagccat gatggaaacg aggattgtat caggccgtat caaacctgct aacgcctcaa
     5161 catcgaccaa gcctttctta tcaactggag aaaaatccac ttcaaatcct tgacttttca
     5221 accagagggc tgactctttg actgctggat gttcaatggc tgaaacaatg atgtgcttgc
     5281 caaactgagc tttttcaaag gccacaccct tgataaccca gttatcccct tctgttccac
     5341 cagaggtaaa gaagatttca tcgcttttct taccgattaa atctgcaatc tgttggcgag
     5401 aagcatctaa gattcgtgtt gcttggtctc ccaaacgatg gagactagat gggtttccta
     5461 aaatttttga agcgacctgc acataggttt caagggcttc aggataaggc ttggtcgtcg
     5521 ctgaattatc aaagtaaatc atgtttctca cgctttctaa aatcactccc tctattgtat
     5581 catgaaacgg agcttgcgac aagaaagggc aatttctctt tttttaagat ttttttaaag
     5641 aaacagagta taataagtca taatcaaagg agagaatgta tgtctaatta tcgtagaact
     5701 tcaaaaccaa aaacagaaca catcaaaaaa ggctttacag tctttcaaaa aaccgttgcg
     5761 actatcgcta gtatccttgg cttgattacc gctagtatca cgattatgaa cgccttggat
     5821 aataacaaaa atactaaaaa ggaacctaca acaagccaga cgacaacaat tgtcaaagaa
     5881 attcaaaagg aatcccctca ggaaaatact agtcccaata aggaaaataa gacttctcaa
     5941 gaaaaaacac aacaagaaga aacgccaaaa tccagcgtca aggaagagaa aaaagaagag
     6001 cagaaaacat caactcagga ttcttctact cctgctccta ctccaagtaa acctgctact
     6061 gaaaacgaaa aacagtccaa taccccaact tcggaaaata aaactaatca ataatcacta
     6121 aaatagcctc cttccaaact tggaaagaag ctattttttt attgttgtaa aacttttctt
     6181 ggtttggtac cttcagctgg accaatgaca cctgccatct caagctcttc catgagacgg
     6241 gtcgcacggt taaatccaac tgacaaacga cgctgaatca tggatgcact ggctttctgt
     6301 gtttcgataa ccaaagactt agcttcttca aaaagcggat caccaccagc atctccatcc
     6361 gaaaattctc cttcattttc agaaacctca cctggatcaa aactctcatc gtagtctgca
     6421 tctgcctgag tcttgatgaa gttcacaatg cgctcaacat cgtcatccga gataaaggag
     6481 ccttggagac gaactggatg attttcatca atcggtttaa agagcatgtc tcctcgacca
     6541 agaagttttt ctgctccatt ttcatccaaa atcgtacggg agtctgttcc tgatgaaacc
     6601 gcaaatgcta cacgagatgg aacattggcc ttaatcaaac cagagatgac atcaacagat
     6661 ggacgctgag ttgcaagaat catgtggata cctgcagcac gcgccttctg cccaagacgg
     6721 atgatagcat cttccacttc cttgctggcc accatcatga ggtcagccaa ctcatccaca
     6781 atcacgacaa tgaatggtag cggaatttgc ttgtactcag actgggaatt gaactcttct
     6841 accttggcat taaaacctgc aatattccga actcccacct tggcaaagag ttcataacgg
     6901 ttttccattt catccacaac cttttgcaga gccttgctgg ctttacgtgg attggtcacg
     6961 actggaatca agaggtgggg aatatcattg taaacagata actcaaccat cttgggatcg
     7021 accatcataa atttaacttg atctggtctc gccttcatga gaatgctagc aataatgccg
     7081 ttaactgcta ctgacttccc tgaacccgtt gaacctgcaa ctagcaagtg gggcatttta
     7141 gaaaggtcaa aagctcttgc ggttccatta acagccttcc ctaaaggaat ttccaagaaa
     7201 ttttctgctt tcgtttgcga ttgttcccat agttctcgga aagatacagt ggcaatatcg
     7261 gagttgggca cttcaattcc gattagggat ttcccaggga ttggtgcttc aatccggaca
     7321 tctttggcag ccaaggctag agcgaggtca tctgatagat tggaaatgcg gttgaccctt
     7381 acaccaacag ccggcttgac ttcatacttg gtcactgatg gcccaatttc ggcccgttca
     7441 actgttacct taataccaaa gctagcaaag gttgcttcta agattttgat attttctctg
     7501 acaattttct tctctttaga ctgatctttt ggtttatctg gtgcaaagag ttgtaagctt
     7561 ggaagtttgt attcaagggc ttctttggct gaaaaatcga cctgaacatc ttggtcatct
     7621 gagtcatctt cctgttcagg gaatttaagt tcagcttgag gcaggatgat ttctggttcc
     7681 acccactttt cttctggaat aggtggaaga ttttgaacag cttcctctgt cagaatttca
     7741 cccgtttcca tatcaacagg aggcaaatcg agtaaggctt tttcagtctc ttcttgttct
     7801 aatctagcct ctttctcagc cttttggcga gctttttctt cttgtttgac aaagcgttcc
     7861 tcttttcgac gctcgtgccc ttcccaccat ttggcaaagc ctctactgaa aaattcagca
     7921 atatcgtaaa cagaccaagg gctgactagg agagaaccca ctaaaatcaa gatagaacca
     7981 ataaagtaag ttccgatatt tgaaaagaga aaggctgttg gaatataaag agcgaccccg
     8041 atcaagcccc ctccagcaaa gctagtcgtt cgaaaaccag tcagatctgt cacaacctga
     8101 gccatggtcc cttttagaac ggacttgtcc aaaccatatt tccaaactaa gtaggcctca
     8161 aaaatcaaga gtaagccagc aaatatggtg aaaaagccag ataagagtcc ttcctgtttt
     8221 cgtatccact tgaaaaagaa gagatagatt aataggccga atatcgccag ataagctagg
     8281 ctacccacta gcaagcgaat taaattataa agggttatac ctgcagcccc taatttgaag
     8341 gctgcgaaaa tcaataaaat cgcaattcct aatgaaatca acattcgttg aatcgcttct
     8401 tttctttcca gttctgcttt agacggtctc cgtcttgttg tacttgtatt cttgtttgcc
     8461 attcttctat tataccatat ttcacaggca tttcgggaag agaaaaagac tgcaccaaac
     8521 ggtccaatct tttcattttt ctatttttta tgcttgtggt ttgcgtaggt aaccataaac
     8581 cacaccactt acgattgctc ctaccaagac agaaacgagg taaaggagag catttgaagt
     8641 aagggcgata acgaagattc ctccgtgtgg cgccatgagt ttgataccag taagaccaac
     8701 gagtccacct gctactgctg aaccaaggat gaagcttgga atcgcacgag ctgggtcagc
     8761 ggcaccaaat ggaatcgctc cctcagtgat aaatgacaag cccatgatga tgtttgtcaa
     8821 accagagtta cgttcttcct tagtaaattt atctttgaaa agaagagttg cgacaaagat
     8881 tgcaagtggt ggcaccattc ctccagccat aactgctgcc atggctacag aaccacctga
     8941 agaaacagtt gctgcaagcg tacctgtacc aaagacataa gctgctttat taactggtcc
     9001 acccatgtca acagccatca ttccaccaag gacgatacca agaaggacag ctgaacctcc
     9061 tccaagaccg cctaggaagt cattcatagc agtgttgatt gcagccattg ggatattcac
     9121 agctagcata acaaatcctg tcaagattgt tccaagaagt ggcaatagaa ggattgattt
     9181 agcaccttcg agtgaacgag gaactttaac gtatttcttg atggcaagaa ccaaggcacc
     9241 tgcgataaat ccaccaacaa gggcacctag gaaaccagat gagacacctg caagagttga
     9301 agttgcttca ccacctgcgg cataaggaat tttaccaaag gcaaaacctt ctttggcaat
     9361 agcaccagcc acgaaacctg ctaccaaacc cggtttttca gcaatagagt aggcaacata
     9421 acccgcaaag actggaagca tcaaaccaaa ggcagctcca ccaattttca tgaacataga
     9481 agctaactca tggtaagaac caagattgcc aaggttttca tttggaacac ccaaagcacc
     9541 gtcaatcaag aaggcaaggg caatcatgat accaccaccg ataacgaatg gtaacatttg
     9601 agatacacca ctcatcaagt gtttgtagaa ggcaccacca aggctttgtt tttcgttaga
     9661 ggctgttgca gctttggcac cattagcggc acggtagact tcagtatctc ctgaaagagc
     9721 caagttaatt agctcttctg tcttacggat accgtcagca actggacgat tgatcaatgg
     9781 ttttccatca aatcgatcca tttcaacggc cttgtctgct gcaatgataa tagctttagc
     9841 cttacggata tcttctgcag ttagttgatt tccaacaccg ctagcaccgt tggtttcgac
     9901 cttgatacca acccccattt cagcagctac tttttgaagg gcttcttggg ccatgtaagt
     9961 gtgggcaata cctgttgtac aagctgtaac agctacgata aagtcaccag agtcattagc
    10021 aggtgcttga acaagttcct cagttttttc tgaagcttgg tcaaaaagtt cgataacttg
    10081 gtctgcagat gttgcttgac gaagtttgtc tgcaaaaccg tctttcatca agtattgaga
    10141 caattctgcc aaggctgcca agtgagtatc attggcacct tctggagctg caatcatgaa
    10201 gaagaggtca gttgcttgtc catccaagct ctcgtagtca acacccttat ttgacttagc
    10261 aaatagaact gtcgcttctt tgacagcagc gtttttgctg tgaggcattg cgattccatc
    10321 acccaaacca gtagaagtca aagcttcacg cgccaaaatt ccttctttaa atgtttcaaa
    10381 atctgttaca taaccgtgct ctgtcaaatt tttaatcatc tcgtcgatga cagctgtttt
    10441 ttcagttgcc tgcaaatcta gcaacatgac atcttttctc aataggtctt gaattttcat
    10501 cttttttcta cctcaacttt tccatatgtt tctttaataa attccgccgt tgccaagtca
    10561 tctgagaagg tagttgccgt tccgcaagcc actccccatt tgaaggcttc tactacgtct
    10621 tttgatttga caaattcacc tgtgaatcca gcaaccatag aatcaccagc tccaactgaa
    10681 tttttgactg ttcctttgat tggtttagcg aagtaagctc cctcagatgt gacaagaagg
    10741 gcaccatcac cagccataga gataataaca ttttgagcac ccttagccag taactcacga
    10801 gcgtatttct caatttcatc taaactttcg agtttaaccc caaaaatcgc tccaagttca
    10861 tgattgtttg gttttacaag aagaggctgg tagtccaaac tatcaattaa ggtctgtcct
    10921 tcaaagtcac agaccacttg cgcaccagtc tggcgcgtca aggaaatcaa atccttatag
    10981 ataacattgc ctagattttt agcacttgaa cctgcaaaga caactgtatc ttctgctgtc
    11041 agactagata aaatagcttt caattcttct agctgaaccg attcaacagt tggacccgtt
    11101 ccgttgattt ctgtttcttg gtctgctttg attttaacat tgatacgagt atcttctgcc
    11161 acctggacaa aacgtgtctc gatttcttcc tctgctaaag tatctgtgat aaatttacca
    11221 gtaaagccac cgataaatcc cgtcgctgta tttggtatat tcaaacgttt caagacacgg
    11281 ctgacattga ttcctttccc accagcaaac ttatcatcac tgtccatacg atttacacta
    11341 ccaactttga cttggtccaa acgaacgata tagtcaatgg atggattgag tgtgactgta
    11401 taaatcatac ttctattacc tccgttttct ccttaataac ctgcaagagc tcatgccctt
    11461 gactagtgat aacgatagcg cgtttgagtg gtgctacctt ggcaaagcaa gtttgtccaa
    11521 tttttgacga atccaccaag acgtaggtct gcttggcatt ctccaaaata gctcttttca
    11581 cagctccctc ctccatatca ggagtcgtat aatagccatc gtcaacacca ttcattccga
    11641 taaaggcacg gtcaaagtgc aattggttaa tctggttaag agcaacgccc ccgatactag
    11701 catctgtcgc cgtcttgacg tttcctccaa ccatgacagt tggaatctgc ttttcaacca
    11761 actgagcggc atggtgaatg gagttggtca caactgtaac attcttattg accaattcat
    11821 gaatcaaaaa agcagttgtt gttccagcat cgataaagat gacatctttt tctttaatga
    11881 gagaggctgc tttctgagcc agcaacttct tttcttgaag gtttttgaca gatttttctt
    11941 gaatggtttc ttcttcctgt aaggagtggg ggagttctgc tccaccatgc acacgacgaa
    12001 gcttgttttc cgcttccaac tcatccaagt ctcttcgaac cgttgattct gacgtttcta
    12061 gcaaactaac taatttttct agagaaacta catgatgctg atttaactcc tctaaaatta
    12121 gttgtttacg ttctgttttt aacactgaat cacctcctgt tatcgtttac actattcatt
    12181 ctatcatact ttctttcgaa gtcaagcatt ttttatcatt ttctttcaaa atctatcatt
    12241 tttcttattt ctagaatttt tattgcaaga taagagcctt tatggtagac tatttgagta
    12301 agtattggaa gattactcaa gaggcttaag aggccgtgtt ggaaacgcgg taggcgtgta
    12361 atagcgtgcg tgggttcgaa tcccatgtct tccgtcgaaa aaagattatt tttaggatgc
    12421 gacaaatgtt gtatcctttt ttctatcctt ttttctatcc tttttttaaa atagggtctg
    12481 tttgtgactc cctttttagc aaaagaatgc aaaggaatac caaagataaa aataaaaaac
    12541 gttgatttaa caacgtttta ccaaggaatg caaaagaatg caaaggaata atggagccgg
    12601 tgggagtcga acccacgtcc aaacacctgc caacatattt gtctacaacc ataggttatg
    12661 tattatttta acagcccctc gacacataac tcaagtctag aaactgcgag tctatcaatc
    12721 tcttatcaag ccgctagaca aggcttaatc gtatctcgct aataataaga cctgtcattg
    12781 aacacgagca atccaaatcg ggtcacgcct gctggttttt aggcagctag agcgtaagaa
    12841 gtgttatttt ttgcagttat atttaactga gcgtttacgt cgccacacga gtcgcaaaat
    12901 atgcctcata atgcctgtcg aatccgtaac gaccccaaaa gacaataaaa ccattatacc
    12961 ttatctaact caaaaatgca aaaagaaatc acatacctaa gatgaagcta tctgttttga
    13021 agaaattcac gaagagaatt attctaaaat actttcagat gagaattttc gtactctctt
    13081 tatttcaatt catttgagtt taaaaa
//
LOCUS       DAVLDI010000061        13105 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLDI010000061 DAVLDI010000000
VERSION     DAVLDI010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13105
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.061"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            109..918
                     /locus_tag="VXD01_001866"
     CDS             109..918
                     /locus_tag="VXD01_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV0602208.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALC
                     EYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE"
     gene            923..1624
                     /locus_tag="VXD01_001867"
     CDS             923..1624
                     /locus_tag="VXD01_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0602209.1"
                     /translation="MSQIWTKEKFISQVQGGVIVSCQALPGEALYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVVSEFIKKIKEKYPNQLLMADVSNLDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            1649..2566
                     /locus_tag="VXD01_001868"
     CDS             1649..2566
                     /locus_tag="VXD01_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEV0602210.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQDRVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHIACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAASNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            2594..4135
                     /locus_tag="VXD01_001869"
     CDS             2594..4135
                     /locus_tag="VXD01_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEV0602211.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSS
                     WEVRH"
     gene            4154..4612
                     /locus_tag="VXD01_001870"
     CDS             4154..4612
                     /locus_tag="VXD01_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0602212.1"
                     /translation="MIISEQSDFKRYASVNKYFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            4614..6836
                     /locus_tag="VXD01_001871"
     CDS             4614..6836
                     /locus_tag="VXD01_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEV0602213.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPV
                     APTTPISEVQPTSDNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     KELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            6876..7985
                     /locus_tag="VXD01_001872"
     CDS             6876..7985
                     /locus_tag="VXD01_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV0602214.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEFEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            8142..9032
                     /locus_tag="VXD01_001873"
     CDS             8142..9032
                     /locus_tag="VXD01_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV0602215.1"
                     /translation="MKIIGIDIGGTTIKADLYDEFGTSLNHFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYTLNHSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTAEIEKRF
                     GLYTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRSGDKVAEETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILDSKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            9057..9380
                     /locus_tag="VXD01_001874"
     CDS             9057..9380
                     /locus_tag="VXD01_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602216.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENDANIQYISSSRRGEFVEKIIGRVV
                     EKYGH"
     gene            9370..11361
                     /locus_tag="VXD01_001875"
     CDS             9370..11361
                     /locus_tag="VXD01_001875"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEV0602217.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQIFHTSNSNHGVIEGNDALTYLMNQQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERHIQSNNEEIERLIKW
                     EKLEIVPANLEQFSFCKGKVGTIPRTEDNRLYNSLLENNIEVQEIFSNDREYGVVVFY
                     QSSYSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKYLID
                     LQWQIDYILSIYARQISKNNFLCTPHLVALEGWIEETRILYFIKVMDEHFGHSIYIYE
                     SETLTDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGTMLALKIFHLPSATKRFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ISTTSDVMTILVVSVVFGFITVFAGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDMRPLFVLGKWVSIFNAVGILIVSIIQTKSLSGIGAGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGILAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            11377..11853
                     /locus_tag="VXD01_001876"
     CDS             11377..11853
                     /locus_tag="VXD01_001876"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEV0602218.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            11887..12468
                     /locus_tag="VXD01_001877"
     CDS             11887..12468
                     /locus_tag="VXD01_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602219.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSLIIKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALLEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNYLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            12533..>13105
                     /locus_tag="VXD01_001878"
     CDS             12533..>13105
                     /locus_tag="VXD01_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEV0602220.1"
                     /translation="MDTNLFSKINTTISVKENDFITEEKFQKIIQSKDTETLAFILES
                     TPYHLSIDILEDPSQTEISLMTKLVNDYRWAYAESPSDIIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVREVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVE"
BASE COUNT         4470 a         1864 c         2560 g         4211 t
ORIGIN      
        1 tgaaacgaaa gaaattggaa actagtttct aatttatgaa aaatattgaa aaaaaaaaaa
       61 agtgttaaaa taaagaatgt aaacgtttac ttcaactaag gagctcatat gttactgcaa
      121 aaagaactaa ttccaatgat agaagctaac ttaccaaata tggcatatgc tgaaaaagac
      181 attgctaaat tcttcttaaa acagcaacct ctgaatgatt attcatctaa agcattgtgc
      241 gaatacctta atgtatccaa agcaacattg actcgatttg cgaaaaaatg tggttttaaa
      301 ggttttagac aattcatttt caaataccaa gagatgattc atgagaaaga aaagttggca
      361 ttatatacag aggcaacaga aaaagtttta tccgactatg aggaaatgtt gagaaaaact
      421 tacacggttc ttgatgaagt tcaacttgag cgtattgctg agatgataga aactgctgag
      481 cgtgtatatc tctacggtaa aggaagttct gttcttgctt tacaagaaat gaagatgaga
      541 tttatgcgtc tcggagtgat tggtgaagta ttatcagacg aggatatgat tttgtggagt
      601 agcttactac ttaatgaaaa ttgccttgtc attggagcat ccatttcagg tcaaactgat
      661 attgtactag aaggtctaca aaaagctgca gataaaggcg ctaaaacagt tttaatgact
      721 acaagaaaat ttgacgaaga agattgtttc tttgatgaac tattgttatt agcttcgacc
      781 gatcatctct cgtatggcaa tcgcatatca cctcagtttc caatactttt aattacagac
      841 tgcttattct ctaattatct ggaaagtcca gagagacaat attattacaa tcaaactatt
      901 atccataagg aggaataata aaatgagcca aatttggact aaagaaaaat ttataagcca
      961 agttcaaggt ggagtcattg tttcttgtca agctttacct ggtgaagccc tttataatga
     1021 agaatttagc ttgatgcctt ttatggctaa agcagcttta gaggcaggag cagtgggcat
     1081 tcgcgcaaat tctgtgcgtg atattaaagc aattcagaaa gtagtagatt taccaataat
     1141 tggaattatc aaaagggatt atccacctca agaaccatat attactgcta cgatgaaaga
     1201 agtagatgaa cttgtagaat gcggaacaac agtcattgca tttgatgcaa ctttaagacc
     1261 aagatatgat ggcttagttg tcagtgaatt tatcaaaaaa ataaaagaaa aatatccgaa
     1321 tcaattgctg atggcggatg taagtaattt agatgaaggt ctctatgcat ttaaatcagg
     1381 cgttgatttt gttggtacaa cattatcagg ttacacaagt acaagtgtac aatcagatga
     1441 gcctgatttt gaactaatga aaaaattggc tgattttaat attccggtaa ttgccgaagg
     1501 aaaaattcat tatccagaac aattaaaaaa agcttatagt ttaggtgtta ccagtgtagt
     1561 cattggtgga gcgattacac gtccaaaaga aattgctcag cgatttatta atgtcatcaa
     1621 ataaaaaaca atataaagga gaaatctgat gaaagattta actaaataca aaggcgttat
     1681 ccctgcattt tatgcttgct atgatgaaaa tggtgaaatt agccaagatc gtgtaaaatc
     1741 tctggtacaa tatttcattg acaaaggtgt aaaaggtatc tatgtaaatg gttcttcagg
     1801 tgaatgtatt taccaaagtg tagaagatcg taaacaaatt attgaagctg ttatggaagt
     1861 tgctaaaggt aaattaacag ttatcaacca tattgcatgt aataacacga aagatagtat
     1921 cgaattggca aaacattcag aaagtgttgg agtcgatgct attgcagcta tcccacctat
     1981 ttatttcaaa ttgccagagt attcaatcgc agcatattgg aatgcaatga gtgaagctgc
     2041 gtcaaataca gattttatta tctataatat tccacaattg gcaggggttg cgttgactgg
     2101 tagtttgtat gcaacaatgc gtcaaaatcc tcgtgtgatt ggagttaaaa attcttctat
     2161 gcctgtacaa gatattcaaa tgtttgtagc tgcaggtgga gaagattaca ttgtattcaa
     2221 tggtccagat gaacaatatc ttggtggtcg cttgatggga gcagaagctg gtattggtgg
     2281 tacttatggc gttatgccag atttgttctt gaaattggaa agtttgattc aagaacgaga
     2341 tttagataca gctaaaaaac ttcaatatgc tatcaatgaa gttatctata agatgatatc
     2401 aggtaaggca aatatgtatg ctgtagcaaa agaagttttg cgtctaaatg aaaaacttga
     2461 tttaggttct gttcgtcaac ctttagaagc attggcagaa ggtgacttgg aagttgcaaa
     2521 acaagcagca gaacttattc aacaagcacg aaaagaattt ttataataaa taaaatcaat
     2581 atggagatat gttatgggca caacaggatt tacaataatt gacttaatta tcttgattgt
     2641 ttatttactt gcggtgttgg ttgcaggtat ctatttctct aaaaaagaga tgaaaggaaa
     2701 agagttcttt aaaggagatg gttcggttcc ttggtatgtt acttcggtat ccatttttgc
     2761 cacaatgctc agtccgattt ccttcttggg actcgctggt agctcttatg caggtagctg
     2821 gattttatgg tttgctcaat tagggatggt agtagctatt ccactgacaa ttcgttttat
     2881 cttacctatc tttgcacgga tagacatcga tacggcatat gattacttgg ataaacgttt
     2941 taattctaaa gcacttcgta ttatttcagc actcttgttt attatttatc aattgggacg
     3001 tatgtctatc attatgtacc tcccatcagc tggtttatca gtattgacag gaattgacat
     3061 caatattttg attattttga tgggtgtagt tgcaattgtt tattcttata ctggtggtct
     3121 aaaatccgta ttatggacag actttattca aggtgtgatt ctgattagtg gtgtcgtttt
     3181 agctttattt gtactgattg ctaatattaa aggtggcttt ggtgcagtag cagaaacatt
     3241 agcaaacggg aaattccttg ctgcaaatga aaaacttttc gatcctaact tgctttcaaa
     3301 ctccatcttt ttaattgtga tgggttcagg ctttacaatc ttgtcttcct atgcttcatc
     3361 tcaagatttg gttcaacgtt ttactacaac acaaaatatt aagaaactta ataagatgtt
     3421 gttcacaaac ggtgttttgt cacttgcaac tgcaacagtc ttttacttga ttggtacagg
     3481 cttgtacgta ttctatcaag tacaaaatgc agatagtgca gctagcaata tccctcaaga
     3541 ccaaatcttt atgtacttta ttgcatacca gttaccagta ggtatcacag gtttgatctt
     3601 ggcagcgatt tatgcagcat ctcaatcaac tatttcaaca ggtttgaact ctgttgcaac
     3661 ttcatggaca ttggatattc aagatgtcat ttctaaaaat atgtcagaca atcgtcgtac
     3721 gaaaattgca caattcgtat ctctagcagt aggtttattc tcaattggtg tttccattgt
     3781 catggctcac tcagatatta aatctgcata cgaatggttc aatagtttca tgggacttgt
     3841 acttggtcta cttggtggtg tatttattct tggatttgtt tctaaaaaag caaataaaca
     3901 aggtgcttat gcagcgctga ttgtatcaac catcgtcatg gtatttatta aatacttcct
     3961 tcctccaaca gctgttagct actgggcata ttcattgatt tcaatctctg tatcagtagt
     4021 ttcaggttat attgtatctg ttcttactgg aaataaagta tctgcaccta aatatacaac
     4081 gattcatgat attacagaaa ttaaagcgga ttcaagttgg gaagttcgtc actaatagaa
     4141 aagagaaaat aatatgatta tttctgaaca atctgatttt aaacgatatg cttctgtcaa
     4201 taaatatttt tcaaaagtct gtgatttttt agaaaataca aatttgacag atttagttga
     4261 tggaaaaatt gatattgacg gggaaaatgt ttttgcaaat tgtatgactt atctagctga
     4321 tggagttcca ggagatattt ttgaaactca taagaaatat ttagatattc atattgttgt
     4381 tgaaaatact gaaaaaatgg cagtaacttc cccagttcgt gcccagtcac gtgtaccttt
     4441 tagcgaagag aaggatattg ctttttacga tagcaaagac tatcaaattg ttgaattgct
     4501 tccagggaat atgttggtga cttttgaaga agatcttcac caaccaaaga ttcattgcaa
     4561 tgatgaaacg gttaaaaaac ttgttatcaa agttttaaac gaggaaaaat aaaatgaaaa
     4621 aaaatattaa acaatatgta accttaggta ctgtagtggt attatcagca tttgttgcta
     4681 actcagttgc agctcaggag actgaaactt ctgaagtatc aacaccaaag ttggtgcaac
     4741 ctgttgcacc aacgactccg atttcggaag tacaacctac atcggataac tcttcggaag
     4801 ttactgtaca acctcgaaca gttgaaacta ctgttaagga tccatcttct acagcggaag
     4861 aaactcctgt cttagaaaaa aataatgtta ctttaacagg gggcggagaa aatgttacta
     4921 aagagttaaa ggataaattt actagcggtg actttactgt agtgattaag tacaatcagt
     4981 caagtgagaa aggcttacaa gctctgtttg gaatatctaa ttccaaaccc ggtcaacaaa
     5041 atagttatgt agatgtgttc cttagagaca atggtgagtt ggggatggaa gcgcgtgata
     5101 cttcttccaa taaaaataac ctagtatcca gacctgcttc agtttggggt aagtacaaac
     5161 aagaggctgt gactaacact gttgcagtag tagcagattc agtcaaaaaa acatattctt
     5221 tatacgcaaa tggtacaaaa gtagtagaaa agaaagtgga taatttccta aacatcaagg
     5281 atattaaagg tattgattac tatatgcttg ggggagtgaa acgtgcagga aaaacggcgt
     5341 ttggttttaa cggaacacta gaaaatatca aattctttaa tagtgcattg gatgaagaaa
     5401 ctgttaaaaa gatgacaaca aacgctgtta ctggacattt aatttatacg gctaatgata
     5461 caacaggttc taactatttc cgtattccag ttctgtatac ttttagcaat ggtcgggtat
     5521 tttcaagcat tgacgctcgt tacggtggaa ctcatgattt cttgaataaa attaatattg
     5581 ctacaagtta tagtgatgat aatggtaaga catggactaa accaaaatta acattggcat
     5641 tcgatgattt tgcgccagta ccattagaat ggcctcgtga agttggtgga cgtgacttac
     5701 aaatcagcgg tggtgcaacc tatattgact ctgttattgt tgaaaaaaag aacaaacaag
     5761 tactcatgtt tgctgatgtg atgcctgctg gagtaagttt tagagaagca actagaaaag
     5821 attcaggtta taaacaaatt gatggtaatt attaccttaa attaaggaaa caaggtgata
     5881 ctgattacaa ttatactatt cgtgagaatg gtactgtata cgacgatcgt accaacagac
     5941 caactgaatt ttcagtagat aaaaatttcg gtattaaaca aaatggtaat tatttgacgg
     6001 tagagcaata ttcggtttca tttgaaaata ataaaaagac tgaatatcgt aatgggacta
     6061 aagtccatat gaatatcttc tacaaagatg cattgtttaa agtagtgcca acgaactata
     6121 ttgcatatat ttctagcaat gatcatggcg aatcttggtc tgcaccaact ttattacctc
     6181 ctataatggg acttaatcgg aatgcgccat atttaggtcc tggacgtgga atcattgaaa
     6241 gctcaactgg acgtattctt attccgtctt acactggtaa agagtctgcg ttcatttata
     6301 gtgacgataa tggagcatct tggaaagtta aagtagtgcc acttccttct agttggtcag
     6361 cagaagcaca atttgtagaa ttgagtccag gagtaattca agcatatatg cgtacaaata
     6421 atggtaaaat tgcatattta acaagtaaag acgcaggtac tacttggagt gcaccggaat
     6481 atttgaaatt tgtttcaaat ccaagttatg gaacacaatt atcaatcatc aattatagcc
     6541 aattgattga tggtaaaaag gctgtcattt taagtactcc aaactccaca aatggtcgta
     6601 aacacggaca aatttggatt ggtctaatta atgatgataa tacaattgat tggcgttatc
     6661 atcacgacgt tgattatagt aactatggat actcatattc aacattgaca gagttaccaa
     6721 atcatgaaat tggattgatg tttgaaaaat ttgattcatg gtctcgtaat gaacttcata
     6781 tgaaaaatgt tgtaccatat ataacattta agattgaaga tctgaaaaag aattaaagct
     6841 gaaatttgaa aatatataaa aagaggataa aaattatggt aaattacggt attgttggag
     6901 ctggatattt tggagctgat ttagctcgct caatgaacaa aattgaagat gcaaaagtgg
     6961 ttgcggtatt tgacccaaat catggagaag aagttgctca agagttggga tcagatgttt
     7021 gtgcaagttt agatgaactt gtagcacgtg aagatattga ttgtgtgatc gtagcttcac
     7081 ctagctacct tcaccgtgaa ccagttgtga aagctgctca acatggcaaa cacgtatttt
     7141 gtgaaaagcc aattgcattg tcttatgaag attgtaaagc catggttgac gcatgtaaag
     7201 aaaataatgt catctttatg gctggtcaca tcatgaactt ctttaacggt gtacaccatg
     7261 ctaaagaatt gattactcaa ggtaaaatcg gtaaagttct ttattgccat gctgctcgta
     7321 caggttggga agaacaacaa ccaactgtat catggaagaa acttcgttct caatctggag
     7381 gacatttgta ccaccatatt catgaattag attgcattca gtttatcatg ggaggacttc
     7441 ctgaaaaagc gacaatggta ggaggcaatg tatatcataa aggtgaaaac tttggtgatg
     7501 aagatgatat gctcattgta aacttagaat actctgatga tcgttatgct gttttggaat
     7561 atggtaatgc tttccgttgg ggtgaacact acgtcttgat tcaaggaact gaaggagcta
     7621 tcaaacttga cttgttcaat actggcggta ctcttcgtgt taaaggtgaa ggagaatcac
     7681 acttcttagt tcatgaaact caagaggaag atgatgatcg tacagctatc tataccggtc
     7741 gtggtatgga tggagcaatt gcgtacggta aaccaggagt acgttgccca ttatggttgc
     7801 aaacatgtat tgataaagaa atggaatatc tacatgacat cattaaaggt ggagaaatta
     7861 cagaagaatt tgaaaaactt ctcaatggtg tagctgcttt agaatcaatc gctaccgctg
     7921 atgcatgtac tttatcagtt aaagaagatc gaaaagtaag tctttcagaa atcacaaatg
     7981 cttaactttt gtaaaacaga atagtaaatt cttgtcatta tataatttct aaagttctgt
     8041 gatacaactc attgaataaa gaaatagaga tgggactggg ataatgccca gtcccatttt
     8101 ttatcaaaaa gtaatgagat caaaaatgtg ggagtgttga aatgaagatt ataggtatcg
     8161 atattggcgg aacaacaatt aaggcagatt tatacgatga gtttggaacg agtttgaatc
     8221 atttcaaaga gatagaaaca attattgact atgatttggg aacgaatcag atattaaatc
     8281 aggtctgtga tttaattggt gagtatactt taaatcattc aattgatggt gttgggattt
     8341 ccactgctgg agttgttaat gctaatactg gagaaatcat ctatgcaggc tatacaatac
     8401 cagggtatat cggagtaaac tttactgccg aaatagaaaa acgttttggg ttgtatactt
     8461 ttgttgaaaa tgatgttaat tgtgctgcat taggtgaatt gtggaaggga caagccaaag
     8521 ataagaaaaa tgtagtaatg gttactattg gaacaggtat aggaggcagt attattgtca
     8581 acggacaaat tgttaacgga tttaactata ctgctggtga agtaggttat attcctgtag
     8641 gtaattcgga ttggcaaagt aaagcctcaa caaccgcatt gattcattta tatcaaaaaa
     8701 agagcttgaa aactaatcaa actggacgta ctttcttcac tgatttaaga tctggagata
     8761 aagttgctga agaaactttt gaaatttttg tagaaaatct aacaaaaggt ttattaacga
     8821 tttcttatct acttaatcca gaaattctca tattaggagg tgggattctg gatagtaagg
     8881 atattttgtt acctgaaatt caaagttctt tagctaaaaa tgcaatggat aataggtttt
     8941 tacctaaaaa tcttgtggca gctacattag gaaatgaagc tggtcgtata ggagctgtaa
     9001 aaaatttctt agatagaatt tctaataaat agtatgtaag ataaggaggt gtcacaatga
     9061 ctaactctgt attttcgaca atgcaagata ttgagaatgt tgcaaccgat attataaaat
     9121 catatgataa tgagatttat acttataaag ctgtttccca agaagaattg gaaaaactag
     9181 aaaaaagtta tgatgaaaaa agtcacgaag aattagtttc aatagaaagc aatttagaaa
     9241 tgaaacaaca gaaccttatt gatgaggtta ataaaacaat caaggaaaat gatgcaaata
     9301 ttcagtatat ttcatcaagt aggagaggag aatttgtaga aaaaattatt ggtagggtgg
     9361 tagaaaaata tggccattag tcagatgaaa agaatctctc tactattttc taaaagtagt
     9421 cttgatgatg ttttaaaaac tattcaagaa ctagagtcag tgcagttccg tgatttaaag
     9481 gttcaggata attggtcaga agctctagaa aaagatgaag ttgtatttcc aactattcaa
     9541 atttttcata cttctaattc caatcatggg gttattgagg gaaatgatgc cttgacttat
     9601 ttgatgaatc aacaacaaca tttagaagca actgtagaga aattacaaga atacctaccg
     9661 aaagaaaaca cgtttaaatt attgcagcaa cctccgataa ctacctctta tgaagaatta
     9721 gagaaatttg gtaaagctaa tgttgctgag ggtgttctta aaaaagtgaa tcatcaaatt
     9781 aacagagttc atgaattaga aagacacatt caaagtaata atgaggaaat agagcgatta
     9841 ataaagtggg aaaaattaga aattgttcct gcgaatttag aacaattttc tttctgtaaa
     9901 ggaaaagtcg gaacaattcc aaggactgaa gataatcgct tatacaatag tcttttagaa
     9961 aacaatattg aagttcaaga aatattttct aatgatagag agtacggtgt tgttgttttc
    10021 tatcagtcta gttactctat agattttgat gaatacttat ttgaaccatt tgattattct
    10081 agaaaggaat taccgaagca gcgagtagta gatttagatc aagaaaacat gcagttaata
    10141 actgaaaaag agaatattat cgcatcgttg caagattcaa agaaatattt gatagattta
    10201 caatggcaaa tagactatat tttatctatc tatgctcgtc aaatctctaa gaataacttt
    10261 ttgtgcactc cgcatctagt tgcattagaa ggatggatag aagaaactcg tattttatat
    10321 tttataaaag ttatggatga gcattttgga cattctattt atatttatga atcggaaaca
    10381 ttgacggata atcaagatga aatacctatc aaattaacga atcattcttt aattgaacca
    10441 tttgaattat tgacagaaat gtatgctctg cccaaatatt atgagaaaga tcctacacct
    10501 gtattagcac cattttactt tacatttttt ggaatgatgg ttgctgattt aggctatggt
    10561 ttactattgt ttttaggaac aatgttagca ttaaaaattt ttcatctacc ttcagcaact
    10621 aagagatttt taaaattctt taatatatta ggggtagccg ttgcaatttg gggtggaatc
    10681 tatggctcat tttttggata tgagttgcca tttcatctga tatctacaac ctctgatgtt
    10741 atgactatat tagtagtgtc agttgtgttt gggtttatta cagtatttgc aggtttgtta
    10801 gcttcaggac tacaaaaagt aagaatgaag aaatatgcag aagcatataa ttcaggattt
    10861 gcgtggtgtg ttattctgct tggcttgtta tttattgctg ttggaatgtt gatgcctgat
    10921 atgagaccgt tatttgtatt agggaaatgg gtatctattt ttaatgctgt ggggattttg
    10981 attgtttcta ttattcaaac caaaagcttg tcaggtattg gagcaggatt gtttaatcta
    11041 tataacattt catcttatat aggtgattta gttagtttca ctcgattgat ggcattagga
    11101 ttatctggag caagtatagc atcagctttc aatttaattg ttggtttgtt tccgggaata
    11161 ttggctaaac tgacaattgg attagtatta ttcattcttt tacatgcgat caatattttt
    11221 ctatcgttac tatcaggata tgttcatgga gcacgtctga tatttgttga attttttggt
    11281 aagttttatg agggtggagg aaaaccattt caacctttga aggcttctga gaaatatatt
    11341 aaggttatta caaagaatta atggaggata tatataatgg aacatttagc aacttatttt
    11401 tcaacctatg gaggagcttt cttcgctgca ttgggaattg tattggcggt tggattaagc
    11461 ggtatggggt ctgcttatgg agttggtaag gctgggcaat ctgccgcagc tttactgaaa
    11521 gaacagcctg aaaagtttgc ctcagctttg atattgcaat tattgcccgg aacacaagga
    11581 ttatatggtt ttgttattgg aattttaatt tggttgcaat taactccaga acttccttta
    11641 gaaaaaggcg ttgcttattt ctttgtagct cttccaattg ctattgtagg atacttttca
    11701 gctaagcatc aaggaaatgt agcagtagcg ggaatgcaaa tcttggctaa aagaccaaaa
    11761 gaattcatga agggagcaat tttagctgcc atggtagaaa cctatgcaat tcttgctttt
    11821 gtcgtatcat tcattttgac ccttcgtgta taagaaataa atttgcaatt caaaggaggt
    11881 gtctaaatga gcaatttaga aaacttacga gagtctgtta ttgaacaagc tcatgaaaaa
    11941 gggcgtatga aattattgga ttccaaaaag aagattgatg atgaatttga aatgcaaaag
    12001 tcgctcatta taaagaaaaa agaagctgaa catgaacgaa agttaaaaga attgcaacag
    12061 aaatatcaaa taatttttca acaattaaaa aataaggaac gccaatcaac gttagtatca
    12121 aaacagaaaa tattaaaaga actttttcaa tctgctttac tagaaatgga atcttggagt
    12181 gcagataaag aaatggagtt catctatcga attctggaac gatattcaca acaagaggtc
    12241 atagtaacct ttggggaacg gactttagct aaattcaatt tggaacaatt agagaaattg
    12301 aaattctctt ttccaaatta tttatttagt gaacaaccta tctcaaatga atcaggctta
    12361 cttatttcaa taggtaaaat tgatgataac tatttgtata aaacattaat tggatcgatt
    12421 tctaaggaag aaagttcaag tatcgcaaat caaattttta tcaattaagg atgaaattgg
    12481 ttaatccttc ttagaaattt ggagtattcc aataaaatta gaaaggtatt ttatggatac
    12541 taatcttttt tcaaaaataa atacgacgat ttcggtaaaa gaaaacgatt ttattacaga
    12601 agaaaaattt caaaaaatta tacaatccaa agatacggag acattggcat ttatcttaga
    12661 atcaactccc tatcatttat cgattgacat cttagaagat cctagtcaga cagagatttc
    12721 gctaatgaca aaattagtca atgattatag atgggcctat gctgaaagtc cgtctgatat
    12781 aattgtgact ttatttgctt tacgatatgt ttatcataat atcaaagttt tattaaaatc
    12841 taaggcggca attaagaaag atttttctaa attattaatt ccaataggga tttttgatat
    12901 agaaagttta aaacatttag tttcttcctt acattcagat acacttcctg attttatggt
    12961 tcgtgaagta gaatcaattt ggaatgagta tgaaactttt aataatattc gtgtacttga
    13021 tgtcggagct gatctagcat attttaaaca tctgaaactt ttatctaatg agttagatga
    13081 ggtactgtct caggttattg tcgaa
//
LOCUS       DAVLDI010000062        13047 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLDI010000062 DAVLDI010000000
VERSION     DAVLDI010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13047
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.062"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(205..1710)
                     /gene="pyk"
                     /locus_tag="VXD01_001879"
     CDS             complement(205..1710)
                     /gene="pyk"
                     /locus_tag="VXD01_001879"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV0602221.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(1769..2776)
                     /gene="pfkA"
                     /locus_tag="VXD01_001880"
     CDS             complement(1769..2776)
                     /gene="pfkA"
                     /locus_tag="VXD01_001880"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV0602222.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEADFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            complement(2859..5960)
                     /locus_tag="VXD01_001881"
     CDS             complement(2859..5960)
                     /locus_tag="VXD01_001881"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV0602223.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVLEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYVTDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            6308..8581
                     /locus_tag="VXD01_001882"
     CDS             6308..8581
                     /locus_tag="VXD01_001882"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV0602224.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELKVKLPHKIELEKPQLNLVQPQGQAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQAFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRSDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            8598..9068
                     /locus_tag="VXD01_001883"
     CDS             8598..9068
                     /locus_tag="VXD01_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV0602225.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(9185..9340)
                     /locus_tag="VXD01_001884"
     CDS             complement(9185..9340)
                     /locus_tag="VXD01_001884"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602226.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKATLTRIEEI
                     FEEYKSS"
     gene            complement(9611..12961)
                     /locus_tag="VXD01_001885"
     CDS             complement(9611..12961)
                     /locus_tag="VXD01_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV0602227.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
BASE COUNT         3924 a         2870 c         2221 g         4032 t
ORIGIN      
        1 aaactttgaa aacttcaaaa aacggatttt tatcgctttg aacatcaaaa aagaaaggac
       61 gaaatttgtc ctttctcgag cttagctgac ttcaacccac tacagttgac aaagagccca
      121 ttatgaaagt tttgccccct ggacaaaaaa aagagcccat catacaggct agaaagctag
      181 atatgatagg tttttatatt tttcttaacg tactgtgcgg atacgcattg tgtttgtgcg
      241 aacagcttct cctactggca caccagcaac gataacgata tcatcgcctg actcaacgag
      301 acctgcttct accgctttac gttcagcgat ttcgaacata tcgtcagttg aagatggagc
      361 atctgtcaac attgggataa caccccagtt caacatcaag ccacgttctg tcaattcgtc
      421 aaatgtcaat gctaagatgt cagcatttgg acggtattta gaaatcaaac gtgcagtatg
      481 acctgtctta gtaagagtta caaccaattt gatatccatt gagctagtag catctttaac
      541 agcagaagcc attacttctg tcttagagtt acgctcaaat gaatctgaat caagacgtcc
      601 gtattcatta agaagagctt gagcgttctt gtcgattgta gccattgtag ttactgactc
      661 gagtgggtat ttaccgtttg cagactcgcc tgacagcatt gtagcgtcag ttccgtcgat
      721 aacagcgttg aatacgtctg atacttctga acgagttgca cgtggttttt cagtcattgt
      781 ttcaagcatg tttgttgcag tgataacaac tttacctgca gcattgactt tcttgataat
      841 cattttttga taaactggaa ccatttcgaa cggtacttcg atacccatat caccacgagc
      901 aatcataata ccatcagctg cttcgataat ttcgtctaag ttatcgatac cttgttggtt
      961 ttcgatttta gcgaacaatt gaacatgtcc gtttccagtt tcttcacaga ttgcacgaac
     1021 ttcgttcaca tcttttgcag tacgtacgaa tgaaattgcg atgaagttga taccttgttc
     1081 aagaccgaaa cggatatcgt cgttatcgcg ttcagcaaga gctgggaaag gaattttagt
     1141 gttagggatg ttcacacctt tttgtttagc gatgatacca tcgttttcaa cttcaacttc
     1201 aaattcacga gttgcatcat ctttagcaac cacacgaaga ccaagtttac catcgtcaac
     1261 caaaacttga cgaccaactt caacatcatc atagatatca agagcaccag caacgttcaa
     1321 cgcaatcact tcacgagttg atttgattcc ttgtttagtt gcaacacgaa ttttttcacc
     1381 agttttgtat gaatattctt tagcttcacc ttcgaacaat tctgtacgga tttcaggtcc
     1441 ttttgtatca agaaggaaac caactttttt acctgcaatt ttttccgcaa gtttaacagt
     1501 tgccatacgc tcaccttgtt cttggtggtc gccgtgtgag aagttgaatc ggaatgtgtt
     1561 agcaccagct tcaatcaatt tagcaatgtt tttagctgaa gcttcaacat caagtttttc
     1621 accccagtat ccgtcctcac cgaatttttt accaccacgg atttctaccg caggacccaa
     1681 agttgcaacg atttttacac gtttgttcat gatttttgtg actcctttat atatatgacc
     1741 tttttggtct tattaactaa attgtaaatt atgacaagct cttattcaag ctagatagct
     1801 caatatcggc tttgtgtggg ttgttaacca caatcttacc ttctgcagta aggctaaaca
     1861 atgccccttc ttctgcagta ccaagaattg gattttcaac cattttttcg ttacgaatac
     1921 caaccgcaac accaccgata ccttctttaa gaagtttaac agcatgtgca cccatacgtg
     1981 acgccaaaac acggtcacgc gcagttggag aaccaccacg ttgaatatgt ccaagttctg
     2041 ttacacgaag gtcgcttgta tctccagctt ctttaagttt ttgaccaaat tcagccgctg
     2101 acatcacacc ttcagctaag acgatgatat tgtgtttttt accacattca taaccagctt
     2161 tgatgcttgc tacgatatct tccatcttga agtctgcttc agggatgatg atttcatcag
     2221 caccagttgc aataccagcc caaagagcga tatcaccagc gttacgtccc ataacttcga
     2281 ttacaaaagt acgacggtga cttgatgatg tatcacgaat cttatcaata gcgtccatgg
     2341 cagtagtaac cgctgtgtca aaaccgattg taaagtcagt accaacgata tcgttatcga
     2401 ttgtacctgg aagaccaata gctgggaagc catgttcagt caaacgcata gcgccgtggt
     2461 aagatccgtc accaccgata acaactacac cttcaattcc gtgttttttc aattgctcaa
     2521 tccctttaag ttgcccttca agttgagcga actctggata acgagctgag tgaagaaaag
     2581 taccaccacg agaaatgatg tctcctactg aagctgcatc taggggatga atttcaccag
     2641 caaccatacc agcatatccg tcatagatac caaacacttc cattccttct gaaattgctt
     2701 gacgaacaac tgcacggata gcagcgttca taccaggtgc gtctccgcca ctagtcaaaa
     2761 cagcaatacg tttcatattg gtttatgctc ctttttcttt taacattctt cttgattata
     2821 tcacatttga ttttaaaatt cttctatttt ccgtattttt agcgataaat cgttttcata
     2881 acgatttcat tcaatttctc ctctaattca ttggatttag ctacaaaatg atggggagaa
     2941 acgatggttt tctgttcctc ttcataccgg atgatgactg ggattgggcc tttaaattgt
     3001 tctaaaatac gtgaaatttc ttgatccgat tcatgatttt tcacctgtat ccaaaagcgt
     3061 tcagcaactg cttctcttat ttcttgtgca atcatttgca gacggccatc acgtgattgt
     3121 atttttcctt ttacatagta gaaggctccc tcttttattt cctgtccgac ctgacgatat
     3181 aagtctgaaa agagagtgac atccaatttt ttcttactat catctgcctg taagaaggcc
     3241 atattttcac cctttttggt acgaatcact tttattttct gaacttcaac caaaataata
     3301 gcatagctat tttctgacaa atttccgatt ggggtaatcg ggtaaatagc cttacttgca
     3361 atagcttgta gtggatgttt gctgacacct atccctaaaa gctcttgttc catataaaat
     3421 ttttcttgtt ccgtccaatc ttccgattcc tgccaactat aaatagcatc tccaaacaaa
     3481 cttcccaact ctttcacaaa ttcaaataga ttagctaagt tattaaatac tttttgacga
     3541 tttttttcaa atgaatcgaa aagaccaact tttaccaaag gttctagcag aggaagtttc
     3601 agataattct caggtaattt agctataaaa tcttcaatgt tagaataagg tctatgttca
     3661 ataatccaga gagctaaatc attactgact cctttaatgg atttcaaacc tagatagatg
     3721 gccttgttgg caattttatc gtgataggga atcgtgttga tggacaatgg ggctacttca
     3781 aaacctgctt ctaaggcatc tgttacataa tcactgttag cagaattcaa cataatctga
     3841 taaaatatgg ctggataatg tgttttaaaa taagccaact ggaaggccaa ggctgagtag
     3901 gcgtaggcgt gtgacctgtt aaaaccatag cctgcaaact tctccagaac atcaaaaacc
     3961 tgctctgctt tttccgcagt atggcctgct tctatggagc cttgaataaa ggaagccctc
     4021 atctcatgca tagcagaagc atccttttta cccatagctc gacgcaaaat atcggccttc
     4081 ccaagactaa atccagcaaa tcgctgggca acctgcataa cctgctcctg atagagcatt
     4141 atgccgtagg ttggagccaa aatatcctcc agtactggat ccagaacagt cacttcttcc
     4201 tgcccatgct ttcttgccac aaaattattg atatagtcac tagcacccgg tcgatttaga
     4261 gaagtagtcg cgacgacatc ttcaaaacag actggttgca cacgcttaag cagacgaatg
     4321 gcacctggtt gctcaaattg aaagatacct tttgtattac cagaggcaaa taaagctaac
     4381 gtttctttgt cttctaaatc gatttcttca attttcagat gaataccttc tgtttcagca
     4441 agcaactctt gcatcttctg gacaaaggtc aaatttcgta gtcccagaaa gtccatcttc
     4501 aaaagtccgc tagcctcaac tccatgagca tcatactgag tcagtggaat ttcatcacca
     4561 tactttagag gaatgtagtt ggttaaatct tggtcactaa ttacaacacc agccgcatgg
     4621 acagaggttt gccttggata gccctctatc ttgcaagcaa tctcaaaagc tttttggtat
     4681 tctaacttac tattgatttg ctgacgaaac tggagattgc cctcataggc cgacttaaga
     4741 ttgtcacgaa aactgatttt cttagtaatt gcagataatt catactctgg cacaccaaag
     4801 cgtttcaaga catctcgaag agcttgcttg gctccaaagg ttgaaaaagt aacgatttgt
     4861 gccgcatgtt tactaccata tttattacca acatatctga taaaatctgg acgataaata
     4921 tctgggatat caatatcaat atcaggcatg gtatagcgtt cacgattaag aaagcgttca
     4981 aaaatcagat ttttctctac tgggtcaatc cccgtgatgt ctaaggcata agaaaccaaa
     5041 ctgcctactg cagaacccct tcccattccc atataatagc cattcgatcg tccaaaacgc
     5101 aacaaatccc aaacaaccaa gaaataatca tcaaagccca tatcatgaat aacagacaat
     5161 tcttggtcta gtctatcttg atattcttta ctagtcaacc ccttctgaac aagccccagt
     5221 tcagcacgct ctctcaactc ctctactgct ggtctagctg gattaaaacg aggcagtttc
     5281 agactagtat ccaagtcgta agaaatgcct gaaataagct tttctaaatt gtccaaagct
     5341 tgcggaaaac gctcttggaa tagtttctct aaagaacttg ctgatataaa gacatcttgt
     5401 ctcgaacgca agggaacttc tctgagcggt agattttctt taatcgctgt taaaacttga
     5461 agaacttctc tatccctgct ttcaaaagcg ttgacccgat aaagaggtaa gataggatga
     5521 tgaaattcgc ttgctagtgt ttctggataa acccctatat agtaatcaca gcctagttct
     5581 aacgactcaa ctctatcaaa ataaggcaca atgaccgcga tatcctccag gtactgggac
     5641 aggactgacc aagttttctc cccctgcatc ttggctgtcg aaagcttcat caactgctga
     5701 tagcccacac tagatagagc taaaaagcgc aaattcactt cctgatcatc tacaaacact
     5761 gtcatttcaa gccctagcaa aggatgaatg ccgtattttt ttgtaatctc tagaaagtcg
     5821 aaagcgccat aaagattgtc aatatccatc atagccaaat gagtgtagcc gtattcttta
     5881 gctgctctca catacttttc gatcgaaatg acgctttcca taaaactata gactgttttt
     5941 gtatctagtt gtgcgatcaa tttacacttc tcctctatcc ttctcactat attataccat
     6001 tttcacctat aaatggcttc tcttgagaaa aatttcatca gcttactaat ttattttcta
     6061 ttcatttgta tttttgtcat catttttata tttatactat attgtatata aaaatagaaa
     6121 gcatataata taaatctcct agaactttta taccctatct attttattct tattgttact
     6181 ctgttctcta tattgaattt agtactttat tcatttttat tggattattt ccttttgaag
     6241 ttaacaattc cctttctgct ttttttttga tataataacc ttaactgtca ttctatatgg
     6301 aggttctatg cgttttaatc aatatagtta tatcaatttt ccaaaagaaa atgtcttatc
     6361 tgaactaaaa aaatgtggct ttgatttaca aaatacagcc aatcacaaag actcacttga
     6421 aaccttttta cgtcgtttct ttttcactta tcaagacacc aactacccac tttctatcct
     6481 agcagctgat aaaaaaacag acctgctgac attttttcaa tcagaagatg aactgacagc
     6541 agatattttt tatactgttg cttttcaact tttaggcttt tcttatttgg ttgacttcga
     6601 agatagtgac gtttttcgta aagaaactgg atttcccatt atatatggtg acttgattga
     6661 aaatctctat cagttactca atactcgcac caaaaaagga aatactctta tcgaccaact
     6721 tgttagtgat ggtcttattc cggaggataa tgactaccac tactttaacg gcaagagttt
     6781 ggctactttt tctaaccagg atgtcattcg tgaagtcgtt tacgttgagt ctcgtgtcga
     6841 tactgaccaa aaagggctat cagacctagt aaaggttagc attattcgcc ctcgttttga
     6901 tggaaaaatc cctgccatca tgacagccag cccttatcat cagggaacca atgacaaggc
     6961 tagtgacaag gctctctaca agatggaggg cgagcttaag gttaagcttc ctcacaagat
     7021 tgagctagag aaacctcaac taaatctcgt ccaaccccaa ggtcaagctg agcttatagc
     7081 agaggctgag gaaaagctaa ctcacatcaa ctctagctat acactaaacg actacttcct
     7141 tccgagaggc tttgccaatc tctatgtctc aggtgttggt accaaagact cgacaggttt
     7201 catgactaat ggagactacc agcaaatcga ggcttataaa aatgtcatcg attggcttaa
     7261 cggccgttgc cgtgccttta ctgatcacac gcgccagcgt caagtcaagg ctgattggtc
     7321 aaacggaaaa gttgctacaa cgggactttc ctatctaggt accatgtcca atggtcttgc
     7381 gactacagga gtcgatggtt tagaagttat cattgccgag gcaggaattt catcatggta
     7441 caactactac cgtgaaaacg gtctggtgac tagcccaggt ggttatccag gtgaggactt
     7501 tgactccctt gctgagttaa cctattctcg taatctctta gctggcgact atatccgtgg
     7561 caatgaagct caccaagctg acttagaaaa agtgaaagct cagctagacc gaaaaactgg
     7621 ggactacaat cagttttggc atgaccgcaa ttatctgctc aatgcccata aagtaaaggc
     7681 agaggttgtc tttactcatg gttctcagga ttggaatgtc aaaccacttc atgtttacca
     7741 gatgttccat gctcttccta ctcatataca caagcatctc tttttccata atggtgccca
     7801 tgtttacatg aacaattggc aatcaattga cttccgtgag tccataaatg ccttattaac
     7861 caagaaatta ctaggacagg aaacagactt tcaacttcct actgttatct ggcaggacaa
     7921 tacagctcca cagacttggt tatcacttga taacttcggt gggcaagaaa actgtaaaac
     7981 cttctcactt ggtcaagaag agcaagctat tcaaaaccag tacccagata aggattttga
     8041 gcgctatggt aagacatacc aagccttcaa tacagagctc tatcaaggga aagccaatca
     8101 gattactatt aaccttcctg tgactaaaga tctccaccta aacggtcgcg ctcagctcaa
     8161 tcttcgtatc aaatccagta caaacaaggg gctcttatct gcccaactgc tagaatttgg
     8221 gcaaaagaaa tacctacaac cttatccagc tattttaagt gctagaacca ttgacaacgg
     8281 tcgctatcac atgttggaaa atctctgtga attgccattt agaccagagg cacaacgagt
     8341 cgtgacaaaa ggttacctta atttacaaaa tagaagtgat ttactgttag tagaggatat
     8401 tactgcagat gaatggatgg acgttcaatt tgaactgcag ccaactattt acaagctaaa
     8461 agaaggagac actctccgtt tagtcctcta tactactgac tttgaaatca ccatccgtga
     8521 caatacagac taccacttga ctgtcgacct cgctcagtcc atgcttacct taccttgcta
     8581 aaaggagtta cattattatg aataaatcag aacaccgcca ccaacttata cgcgctctta
     8641 tcacaaaaaa caagattcat acacaagctg agttgcaagc ccttcttgct gagaacgaca
     8701 ttcaagtaac ccaggcaacc ctctcacgcg acatcaaaaa tatgaaccta tcaaaagtcc
     8761 gcgaagaaga tagcgcttat tatgttctta acaatggttc catctcaaaa tgggaaaaac
     8821 gtctcgaact ctacatggaa gacgcccttg tctggatgcg cccagttcaa caccaagtcc
     8881 tactaaaaac ccttcctgga ctggctcaat cctttggttc tatcattgat actttgagct
     8941 tccctgacgc tatcgctacc ctttgtggta atgatgtctg tcttatcatc tgtgaagatg
     9001 cagatactgc tcaaaagtgc tttgaagaac tgaaaaaatt cgccccacca tttttctttg
     9061 aagaataata aatgactaca actaacaatt atgcttaaaa aaaaactggt agaaagtctt
     9121 taacatcaga aaacgcatag tatcaagtgt tgaaaaccct tgatactatg cgttttgctt
     9181 tatcctagga agatttatac tcttcgaaaa tctcttcaat ccgcgtcaac gtcgccttgc
     9241 cgtaggtatg gttactgact tcgtcagttt catctacaac ctcaaaacag tgttttgagc
     9301 agcctgcagc tagtttccta gtttgctctt tgattttcat tgagtattat ttcattttct
     9361 cctgcaattg aattcttgct cagctttttg ttttctattt ctttaaaatc aaagtagctc
     9421 ttttgttaat aactcgatca acaaacatcg tggtacaagt atctactttg aaatttatca
     9481 accacttaac aactgatact gtattctagg aaaacgatga cattcttcct aataaaactt
     9541 ctcatatata gcataaattt ctactctttt taattttaaa tgagtctcag catggcaatc
     9601 actttagaat ttaagccgct tctccagctc gattattgat aagttcaatg atttgaacaa
     9661 tattacgaag tactggtagt tggtgttgga agagtagttg aacagatcca taagatttaa
     9721 acggctcttg cgttaacact ttcgtctcta aaaaaccatt ttctacaatg tagtctacaa
     9781 tcaattttac aaatgaaatc tgcctggcat taagattctc atccgacaaa aatttagaaa
     9841 aaatacgatt ggcagactct ctatctaaac caataatctc acgaaccaat ctcggaattg
     9901 ccttattttc ataatgactt tggtagtctg ctttactacc taatttttcc caaagcaatt
     9961 tttcaagtgc aagcatatca tcagatgtca actttttatt atggtatagc ttagaaatgg
    10021 actcctcatc cagatgagtt ttcaaataat gctcaacttt ttcattgtaa gaccgaagat
    10081 cgttgacctg caaaaatgct gtggtctcgt gaacagtgga gagtatacga tcttcaaagt
    10141 taacatagta gggtttacgg tctgttttat ccaaaaactg taataaatct cgaatagcaa
    10201 gacgaatttt ttccaaatca gacaagttaa cttctttcca aaattcaggc tcctgtactt
    10261 tcctgataat ttcagcctgc tcaaaaacct gcgggatatt gccaatagca gaaagagctc
    10321 tagccgtctt catcacttgg gaaatatgaa cagtggaaga tttagctgtc agttgcccca
    10381 actgaatatg aagcaaccac aaatcaaatc tcctcgccat ctcatcttct ttatcttcat
    10441 caaataaaag cggagagaga tttttttgaa tggtttcact tgtaacagca gttagattct
    10501 gccaactttc caatttccta tagctataaa ctgtatctaa aaccatacga accctgaagt
    10561 ccaactcatt taagctctct atacgacctt gaagttccga gacaagctgc tgacggtatg
    10621 ctctcgcaaa ctgatcttct tggtattgga gtccctgaag ttctcgaatc aagtccactt
    10681 tgatattaaa taaacgctga gtcagcgaaa caatgtgacg accctctcca tctcttggat
    10741 ctgcacgaaa ataatcaaaa ttgtccccat aatcaaatac caagaagttt tccttatcct
    10801 gctcaggtcc aaataaatct ttacatagac gggttcctcg accaatcatc tgccaaaact
    10861 tagttttaga gcgtactttc ttgaagaaga ctaaattaac aacctctggt acatcaatac
    10921 ctgtatctaa catatcgaca gaaatcgcaa tttgaggata cttctcctta attttaaaat
    10981 catcaatcaa ggtctgataa tgcttaatac tataatcaat cacctgagca tagtcgctcc
    11041 ctttttcagg atagcggttg ttaaaaatac ctctgatata ttccgcatgg tcatgatttt
    11101 tagcaaaaat aatagtttta ccaatttcat cacccgaggc tgtctgaatt cctcttgtca
    11161 tgagttcatt taaaacaatt tctactgtac ttttattgaa aataaaggaa ttaaacacac
    11221 tcccatcaat atctttttca cagctatcgt cttcaaattt gctatcaaaa tgttcctttt
    11281 cttcttcgga caaatcatca taatgtagac catccgtagg tagtttcagt ttggtttcga
    11341 tagaatgata ggctactaaa tatccgtctt taacagcctc ttccaaatca tatgcatatg
    11401 ttggaacccc attctccaaa ttaaagaatc cataggtgtt tttatctaaa tcttgacgcg
    11461 gagtagctgt taagcctaca attcttgcat caaaataatc aaaaatggac ttgtatttct
    11521 gataaataga acggtgagat tcgtcaatta tgataaggtc aaaatgccca acagtgaaag
    11581 ggcgttgatt tacttcttct tgaccactaa tcgctccaat catggtcgga taagttgaaa
    11641 agaccatgcg acttgattga gctccttctt tatcttctaa gaagttacaa acggaaagat
    11701 ctgggagtaa ttttctaaac gaatcatagg cttgcttaac caaggaagtt ctatcggcta
    11761 agaagagaac gttttttacc cagttatgac gtgataagat atcaactaga gaaactgctg
    11821 tacgagtttt cccagcccca gttgccataa ccaaaagtgc ctgtctacga tgattagaga
    11881 aagcttcaca aacgcttgca atggcgtgtt tttggtagtg acgcccggaa atatcgtccc
    11941 taattttact agaaatatcc tcaagtggtt tttgaagatg acgtctatcc atcactaatt
    12001 gcaattcttc ttgagagtaa aagcctgcaa tctggcggcg gttcggacca tcaagtatat
    12061 agtgcttcaa gccatttgta ataaagcaaa ttggctgata gccgatatgt ttctcaagag
    12121 cttcagcata ttctttgacc tgtacttccc ctacttctgg attgacagag gcttttttag
    12181 cctctacaat cgctaaaatt ttcccatttt taccataaag tacatagtca cagtaaccaa
    12241 ttcctgaacc gtgcttgaga ccatcaacgg ctatctcaac acgacagttt tcttcaaata
    12301 tccatcctgc taaacggaga tcgatatcaa taaagagctt tcttgtctct gcctcagata
    12361 attgatcaat atggaaaggc acatcttgcc gttgcgctgc agtctcacgt ttttcagtat
    12421 aagtctcttg aacttctacg gactgagcag ccatctgttc atgaaaatca ggcagttctg
    12481 gtaaactgtc ttgtaacttt atcatagatt gtggagtttc tcggtatttg atgtttgctg
    12541 aaagtggtaa gcacttctca tcaaaataac gctccacaaa ctcattgctg taacaataat
    12601 cgataaaatt aacaaactga tacaaatgat gcaaagctaa aatcgcttct cgttccttaa
    12661 tttcaccacc atgagcagca tggtttcccc accgaatcaa cagaactatc tgcttgtgga
    12721 gttcagaatc tacgatatcc ctaaaatcat catcccatac taaagaagat agagtagcac
    12781 gatagggagc ttctaaatat gaatcgtgac tatatatcca atggacagcc tgctctaaag
    12841 cacgacgcgc cataaaggca gtagccacag ttgatgtagc aatcatattc tcagcttcaa
    12901 tgcaaggttt tgaaaaagat tcatattcgt cattttttaa aagaaagcta aaatttccca
    12961 tttttttctc actttaaaca aatagtttag ctatattata ctaaatttca agctatttct
    13021 ccacactttt atagctatct cacaagc
//
LOCUS       DAVLDI010000063        13013 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLDI010000063 DAVLDI010000000
VERSION     DAVLDI010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13013
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.063"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..864
                     /locus_tag="VXD01_001886"
     CDS             1..864
                     /locus_tag="VXD01_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0602228.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDNLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            1247..1867
                     /locus_tag="VXD01_001887"
     CDS             1247..1867
                     /locus_tag="VXD01_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602229.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            1953..2396
                     /gene="tsaE"
                     /locus_tag="VXD01_001888"
     CDS             1953..2396
                     /gene="tsaE"
                     /locus_tag="VXD01_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV0602230.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2386..2904
                     /locus_tag="VXD01_001889"
     CDS             2386..2904
                     /locus_tag="VXD01_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0602231.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLID"
     gene            2912..3928
                     /locus_tag="VXD01_001890"
     CDS             2912..3928
                     /locus_tag="VXD01_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV0602232.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4013..5269
                     /locus_tag="VXD01_001891"
     CDS             4013..5269
                     /locus_tag="VXD01_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV0602233.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGNKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5324..6490
                     /gene="recA"
                     /locus_tag="VXD01_001892"
     CDS             5324..6490
                     /gene="recA"
                     /locus_tag="VXD01_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV0602234.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            6797..8167
                     /locus_tag="VXD01_001893"
     CDS             6797..8167
                     /locus_tag="VXD01_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV0602235.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWVVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSTFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            8543..9499
                     /gene="lytA"
                     /locus_tag="VXD01_001894"
     CDS             8543..9499
                     /gene="lytA"
                     /locus_tag="VXD01_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0602236.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            9845..10006
                     /locus_tag="VXD01_001895"
     CDS             9845..10006
                     /locus_tag="VXD01_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0602237.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            9993..10199
                     /locus_tag="VXD01_001896"
     CDS             9993..10199
                     /locus_tag="VXD01_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602238.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            10245..10604
                     /locus_tag="VXD01_001897"
     CDS             10245..10604
                     /locus_tag="VXD01_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602239.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKVMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMSLG"
     gene            10733..11158
                     /locus_tag="VXD01_001898"
     CDS             10733..11158
                     /locus_tag="VXD01_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602240.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKV"
     gene            11566..12561
                     /locus_tag="VXD01_001899"
     CDS             11566..12561
                     /locus_tag="VXD01_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602241.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            12551..>13013
                     /locus_tag="VXD01_001900"
     CDS             12551..>13013
                     /locus_tag="VXD01_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602242.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFQFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCG"
BASE COUNT         4133 a         2074 c         2824 g         3982 t
ORIGIN      
        1 atgaatacac tcgcagagaa attcagattg aaaagaaaag agttgagact ctcccaacaa
       61 actcttgcag aaggaatttg tgaacaaagt cagattagta aaattgagag agggcatttc
      121 attccctccg cagacctttt gttcaaactc tcacaacgac ttgaagtacc attagattat
      181 ttttttaatg aacaaattga aattaaatct aacctctcta atttcaagca attgtctgct
      241 cgactattag atgacagaaa ttatgataat ttggaatata tttatagaat tgagattgaa
      301 cgaagtactt ttctaacact agaagaccga acttatcttg aatggattaa agctattatt
      361 gacttctatc aatatgacag taagtgtgag gcaatttctt cattggaaaa tatattatta
      421 aaagtctctt caaatactct gatttattta aaggcgttga atactctatc taatttctat
      481 tccttagtgg gtcgtgaaca agaatatgag gcaaactact ctcatttaat agagttgtat
      541 cagacaaaaa atttggacca tcaagagttt ttatttggct acatcagagt tcgttacaac
      601 tacgctcact acctagtatc aaaggaaaaa tataatgaag ccatccaaga agctcttgaa
      661 acgattgaac tctgtaaaca aagacagaca agctaccaat tggctcctct acttattctt
      721 gtaggaaatg ctggagccaa atttctagac agagaacaag tcaaaaatta ttatatagaa
      781 gcaagagagt tatgtaagat ttataacaat cctttaatgt tgatgaagat agaaaattat
      841 ttgaaggaat tagatactgt ttagttaatc ttgacattat agtttttctg aaacgttaaa
      901 taacctgtaa ggctgatagt tagattaata ctatcagcct tatcattatg tgactctgag
      961 tccgtctcgc tccgtgaggt gcgagacaaa acaaccaccc gtttgacgga ttttcatgat
     1021 ttcaaattta tattcttcga aaatctcttc aaaccacgtc agctctatct gcaatctcaa
     1081 aacactgttt tgagcaacct gtggctagct acctagtttg atctttgatt ttcattgagt
     1141 attagtctct agtgtttgtt tagcgtctta aagagacatt tgagaagatt agaaacagtt
     1201 ctctcttttc tcctagtata atgattggta ggaagggaga gagaagatga aatcaatgag
     1261 aatcttattt ttgttagctt taattcaaat cagtttgagt agctgtttcc tatggaagga
     1321 atgcatcttg tcctttaaac aaagtacagc ttttttcatc ggaagcatgg ttttcgtttc
     1381 aggaatctgt gctggagtaa attatcttta tacccgtaag caagaagtcc atagtgtcct
     1441 agccagtaag aagtcggtga agctttttta cagtatgtta ctcttaatta atttgttagg
     1501 agctgttctt gttttgtcag ataacttgtt catcaaaaat acgctgcagc aagaattagt
     1561 tgacttttta ttgccatcct tctttttcct atttgggcta gatttgctga tttttttacc
     1621 cttgaaaaaa tacgtgcgcg attttcttgc tatgctagac agaaaaaaga cagtgttggt
     1681 gactatttta gcaacacttc ttttcttaag aaatccaatg accattgtct cacttctgat
     1741 ttatactgga ctgggcttgt tttttgcagc ctatcttgtc ccaaattcgg ttaagaagga
     1801 agtttccttt tatggtcata ttttccgaga tcttgtattg gtcattgtta cgctcatttt
     1861 cttttagaga aagcctgttt tttatggatg ttatgatgat aagtttagta ggaaaataga
     1921 cacaaaagaa aagtttttgg tataataaga gtatgtacac aaaaaatgaa gaagagttgc
     1981 aagccttagg ggagcgtttg ggccatctat tagcaaagaa tgatgtttta atcttaattg
     2041 gagaactggg tgcaggtaaa acgaccttta ctaaaggact tgcaaaagga ttacagattt
     2101 ctcaaatgat taaaagtcct acctatacta tcgtgagaga gtatgaaggt cgacttccac
     2161 tttatcacct agatgtttat cgtattgaag gagatgctga ttctatcgac ttggatgagt
     2221 ttatctttgg tggcggcgtg actgttattg agtggggaaa tctcttagga gatgccttgc
     2281 cagatgctta tttagaattg gaaattctaa aagaagcaga tggacgccgt ttaaattttc
     2341 aggcaaaggg tttgcgtgct gagaaattgt tagaggagct tcaatatgga gtatgaattg
     2401 ctcattaggg aagcagagcc caaagatgca gctgaattag tggccttttt aaatcgtgtg
     2461 agtttggaga cagactttac cagcctagac ggagatggta ttctcttgac tagtgaggag
     2521 atggaaatat tcctcaacaa gcaagctagt tcggacaatc agataacctt acttgcattc
     2581 ttaaatggca aaattgctgg tattgtaaat attacagctg accagcgtaa gagagtccgt
     2641 catattggag atctcttcat tgtgattgga aaaagatatt ggaataatgg cttgggaagt
     2701 ttgttgctag aagaagcgat agagtgggca caagcaagtg gcattctgcg tcgtctccaa
     2761 ctgactgtcc aaactcgtaa tcaagcagca gtccatcttt atcaaaagca tggctttgtc
     2821 attgaaggta gccaagagcg tggggcatat atagaagaag ggaaatttat cgatgtttac
     2881 ttgatgggta aactgataga ttagtagaaa tatggttaaa aaaattattg gaatggtgct
     2941 agctttactt tctgtaactg tagtaggagt aggtgttttt gcttatacta tttatcaaca
     3001 agggacagaa accttagcta aaacctataa aaaaatcggc gaagaaacca aggttattga
     3061 agcgactgaa cctctaacca ttctgttaat gggagtggac accggaaatg ctgaacgaac
     3121 tgaaacttgg gtcggtagaa gtgatagcat gatcttgatg acagtgaatc ctaaaacgaa
     3181 aaaaacaaca atgatgagtt tagagcggga tattctgacg cgcattgaat cagggaatgg
     3241 tcaggctcat gaagcgaaac tgaactcagc atatgcagat ggtggagcag agcttgctat
     3301 agaaaccatt caaaaaatga tgaatatcca tattgatcgc tatgtgatgg tcaatatgag
     3361 agggttgcaa aaactagtgg atgcagtagg aggtattaca gtcaataata tcctaggttt
     3421 cccaatttct atcagtgacc aagaagaatt taatactatt tctatcggtg ttggggagca
     3481 acatattggg ggagaagaag ccctagtcta tgcacgaatg cgttaccaag atcctgaggg
     3541 ggattatggt cgtcaaaaac gtcaacgtga agttattcaa aaagtcatgg aaaaagctct
     3601 cagtttaaat agcgttggtc attatcaaga gattctaaaa gctttgagtg acaatatgca
     3661 gaccaatatt gatttgtctg caaaaagtat ccctaacttg ctaggctata aagattcatt
     3721 taaaaccatt gaaactcagc agttgcaggg tgaaggagag atacttcaag gtgtttctta
     3781 ccagattgtt tcgagagcac atatgttgga aatgcaaaat atactccgac gttctttggg
     3841 acaagaagaa gttactcagc ttgaaaccaa tgcggtttta tttgaagatt tatttggcag
     3901 agcacctgtt ggtgatgaag ataattaact tttgatacaa ataaaaaaat caatcgtagg
     3961 aaaattcctg cgattttttc aaaaaaatac gaatagatag gtaggaggaa acatgaaagc
     4021 agaaatcatt gctgttggaa cagagatttt gacaggacag attgtcaaca ccaatgccca
     4081 gtttttgtcg gaaaaactag ctgagattgg ggtagatgta tattttcaga cggctgtagg
     4141 agacaatgaa gttcgtctct tgtctttgct tgagattgcc agtcaacgta gcagtctggt
     4201 gattttgaca ggcggtttgg ggccaactga ggacgaccta accaaacaaa ccctagctaa
     4261 atttttaggg aaagcattag tctttgatcc tcaggctcag gagaagttgg atatcttttt
     4321 tgccctgcga ccagactatg cccgaacacc gaataacgaa agacaagctc aaattgtaga
     4381 aggagcgatt ccactgccaa acgaaacagg actggctgtt ggaggaaaat tagaagtaga
     4441 cggagtgacc tatgtcgtcc ttccaggtcc gccaagtgaa ttgaaaccca tggtcttaaa
     4501 ccaacttcta cccaagttga tgacagggaa caagctgtat tcccgagttc ttcgtttctt
     4561 tgggattggc gagagccagt tggttacgat tttggctgat ttaattgata atcagatcga
     4621 tcctaccttg gccccttatg ccaagacagg agaagtcact ctacgtctgt caacaaaggc
     4681 tagcagtcaa gaagaggcga atcaagcgct ggatatcttg gaaaatcaaa tcttggactg
     4741 ccagactttc gaaggaattt ctttacgaga cttttgctat ggttatgggg aagaaactag
     4801 tttagccagc attgtggtag aagaactgaa aaggcaaggg aaaaccatcg cggctgcaga
     4861 gagtttgacg gcaggtcttt tccaagctac cgtggcgaat ttttctggag tttcaagtat
     4921 atttgagggt ggttttgtga cctatagctt ggaggaaaaa tcaaggatgt tggatattcc
     4981 tgccaagaat ttggaagaac atggtgtggt gtctgaattt acagctcaga agatggctga
     5041 gcaggcacga agcaagaccc agtctgattt tggaattagt ttgactggag tggcaggacc
     5101 agatagccta gaaggacacc cagttgggac agtcttcata ggcttggcgc aagatcaagg
     5161 aactgaggtt atcaaggtta atattggagg cagaagccga gcagatgtac gtcacattgc
     5221 ggttatgcat gcctttaacc tagttcgcaa ggctttatta agtgactaac ttttgatata
     5281 atagtagata ggtctgagga tcattagaat gtaggagaat agaatggcga aaaaaccaaa
     5341 aaaattagaa gaaatttcaa aaaaatttgg ggcagaacgt gaaaaggcct tgaatgacgc
     5401 tcttaaattg attgagaaag actttggtaa aggatcaatc atgcgtttgg gtgaacgtgc
     5461 ggagcaaaag gtgcaagtga tgagctcagg ttctttagct cttgacattg cccttggctc
     5521 aggtggttat cctaagggac gtatcatcga aatctatggc ccagagtcat ctggtaagac
     5581 aacggttgcc cttcatgcag ttgcacaagc gcaaaaagaa ggtgggattg ctgcctttat
     5641 cgatgcggaa catgcccttg atccagctta tgctgcggcc cttggtgtca atattgacga
     5701 attgctcttg tctcaaccag actcaggaga gcaaggtctt gagattgcgg gaaaattgat
     5761 tgactcaggt gcagttgatc ttgtcgtagt cgactcagtt gctgcccttg ttcctcgtgc
     5821 ggaaattgat ggagatatcg gagatagcca tgttggtttg caggctcgta tgatgagcca
     5881 ggccatgcgt aaacttggcg cctctatcaa taaaaccaaa acaattgcca tttttatcaa
     5941 ccaattgcgt gaaaaagttg gagtgatgtt tggaaatcca gaaacaacac cgggcggacg
     6001 tgctttgaaa ttctatgctt cagtccgctt ggatgttcgt ggtaatacac aaattaaggg
     6061 aactggtgat caaaaagaaa ccaatgtcgg taaagaaact aagattaagg ttgtaaaaaa
     6121 taaggtagct ccaccgttta aggaagccgt agttgaaatt atgtacggag aaggaatttc
     6181 taagactggt gagcttttga agattgcaag cgatttggat attatcaaaa aagcaggggc
     6241 ttggtattct tacaaagatg aaaaaattgg gcaaggttct gagaatgcta agaaatactt
     6301 ggcagagcac ccagaaatct ttgatgaaat tgataagcaa gtccgttcta aatttggctt
     6361 gattgatgga gaagaagttt cagaacaaga tactgaaaac aaaaaagatg agccaaagaa
     6421 agaagaagca gtgaatgaag aagttccgct tgacttaggc gatgaacttg aaatcgaaat
     6481 tgaagaataa gctgttaaag cagtggagaa atccgctact ttttcgattt ttgattcaag
     6541 tttttagatt atatatagta gcttgaaata agatatgaac aactttatta ggaaagtcaa
     6601 attaatttct agaaatgttt tagcagctac agcgtactat tccaaactca accaactata
     6661 atagatcgaa actagaatag tacacatcta cttctaaaac attgttaaaa atcgatttga
     6721 ctgtccttat ttcattccgc tatatataag tttgctgttt cttgtcgctc ctctggaaag
     6781 ctgatataat agctttatga ataaaaaacg aacagtggac ctgatacatg gtccgattct
     6841 tccctcgctc ttaagcttca cctttccaat cttgctatca aatatttttc aacagctcta
     6901 taacactgct gatgtcttga ttgttggacg atttcttggt caagaatcct tggctgcagt
     6961 aggagcgacg acagcgattt ttgacctgat tgtaggcttt acacttggtg ttggcaatgg
     7021 catggggatt gtcattgctc gttattatgg ggctcggaat ttcactaaaa tcaaggaagc
     7081 agtagcagcc acctggattt taggtgctct tttgagcatt ctagttatgt tgctgggctt
     7141 tcttggcttg tatcctctct tgcaatactt agatactcct gcagaaattc ttcctcaatc
     7201 ttatcaatat atttctatga ttgtgacctg tgtaggtgtc agctttgctt ataatctttt
     7261 tgcaggcttg ttgcggtcta ttggtgacag tctagcagcc ctgggatttc tgattttctc
     7321 tgccttggtt aatgtggttc tggatctcta ttttattacg caattgcatc tgggagttca
     7381 atccgcagga cttgctacca ttatttcgca aggtttatca gcggttctct gcttttatta
     7441 tattcgtaaa agtgtgccag aactcttgcc acagtttaaa catttcaaat gggacaaaag
     7501 cttgtacgcg gatctcttgg agcaaggttt ggctatgggc ttgatgagtt caattgtatc
     7561 tatcggcagt gtgattttac agttttctgt taatacattt ggtgcagtga ttattagtgc
     7621 ccagacggca gctcgacgca ttatgacctt tgcccttctt cctatgaccg ctatttctgc
     7681 atcaatgacg acctttgctt ctcagaatct aggagctaag cgacctgacc gtattgttca
     7741 aggtcttcga atcggcagtc gtttaagtat atcctgggta gtttttgttt gtattttcct
     7801 cttttttgcc agtccagctt tggtttcctt cttggctagt tcgacagatg gttacttgat
     7861 agaaaatgga agtctctatc tgcaaatcag ttcaaccttt tatcccattt tgagcctctt
     7921 gttgatttat cgcaattgct tgcagggctt ggggcaaaag atccttcctc tagtttctag
     7981 ctttattgaa ctaatcggaa aaatcgtttt tgtggttttg attattcctt gggcaggata
     8041 taagggtgtt atcctttgtg aacctcttat ctgggttgcc atgacagttc aactgtactt
     8101 ctcattattc cgtcatccct tgataaaaga aggcaaggca atcttggcaa ccaaagtgca
     8161 atcctagttg gatttactga ataaaatcca tttcctctag tgaaaatcga aaaaacttgt
     8221 gttctcgtct ttagtttggt gttgaaaata gtttaacaga cttttgactt cttttatatg
     8281 atataataaa gtatagtatt tatgaaaagg acatatagag actgtaaaaa tatacttttg
     8341 aaaagctttt tagtctgggg tgttattgta gatagaatgc agaccttgtc agtcctattt
     8401 acagtgtcaa aatagtgcgt tttgaagttc tatctacaag cctaatcgtg actaagattg
     8461 tcttctttgt aaggtagaaa taaaggagtt tctggttctg gattgtaaaa aatgagttgt
     8521 tttaattgat aaggagtaga atatggaaat taatgtgagt aaattaagaa cagatttgcc
     8581 tcaagtcggc gtgcaaccat ataggcaagt acacgcacac tcaacaggta accgcaactc
     8641 aaccgtacag aatgaagcgg attatcactg gcggaaagac ccagaattag gttttttctc
     8701 gcacattgtt gggaacggtt gcatcatgca ggtaggacct gttgataatg gtgcctggga
     8761 cgttgggggc ggttggaatg ctgagaccta tgcagcggtt gaactgattg aaagccattc
     8821 aactaaagaa gagttcatga cggactaccg cctttatatc gaactcttac gcaatctagc
     8881 agatgaagca ggtttgccga aaacgcttga tacagggagt ttagctggaa ttaaaacgca
     8941 cgagtattgc acgaataacc aaccaaacaa ccactcagac catgtggatc cataccctta
     9001 cttggcaaaa tggggcatta gccgtgagca gtttaagcat gatattgaga acggcttgac
     9061 gattgaaaca ggctggcaga agaatgacac tggctactgg tacgtacatt cagacggctc
     9121 ttatccaaaa gacaagtttg agaaaatcaa tggcacttgg tactactttg acagttcagg
     9181 ctatatgctt gcagaccgct ggaggaagca cacagacggc aactggtact ggttcgacaa
     9241 ctcaggcgaa atggctacag gctggaagaa aatcgctgat aagtggtact atttcaacga
     9301 agaaggtgcc atgaagacag gctgggtcaa gtacaaggac acttggtact acttagacgc
     9361 taaagaaggc gccatggtat caaatgcctt tatccagtca gcggacggaa caggctggta
     9421 ctacctcaaa ccagacggaa cactggcaga caagccagaa ttcacagtag agccagatgg
     9481 cttgattaca gtaaaataat aatggaatat ctttcaaatc agaacagcgc atattattag
     9541 gtcttgaaaa agcttaatag tatgcgtttt cttgtggaga tatttccttc aatttttgct
     9601 actatattaa acaaaaatca aaaagcaaac tagaaagtta tgctcaaata aaatctaaat
     9661 ttgacaatgt aaaccgagtc ggatagcttt aagtactgtt ttgaggttga agatacgatt
     9721 tttgatagga actcatcaat tttagatttt taagcagcat caataaattg cttccttgtt
     9781 ttgtcataat ttttttattt aaaaaattat gacaagagtg tgctattctt tttatgagag
     9841 gtgtatgaat atgataaatg tatgtgatgt tggaaaaaga ataaaagaac ttagaatatc
     9901 ttcaaatctt actcaagata agattgctga gtatttgtct ttgaatcaaa gcatgattgc
     9961 caaaatggaa aaaggtgaaa ggaatatcac gaatggattt aagtaataaa gctccaaatc
    10021 ttagaaaaaa gttgggagct gatggtgaat cgccgataga tatttttaaa ttggtacaaa
    10081 agatagaaaa tttgacgctg gtattttatg gactcggaaa gaatattagc ggagtctgtt
    10141 ataaaggaac tcagttcagt ctcattgcag tcaattcaga tatgccatta ggaaggtaaa
    10201 gattttcttt agcacatgga ctgtatcatc tttattatga tgaggtgaag aagagttcag
    10261 tcagtcttat cttgattggt gaaggagatg aaactgaaag aaaagcggat cagtttgctt
    10321 cttatttttt aattttccca tcttcactgt ataggatggt tgaggaaatc agagaaaatg
    10381 ccaatagaac tcatcttgaa gtagaagata ttataaaatt gggtcagttt tatggtatca
    10441 gtcataaagt tatgttatat agattgagga atgatggata ccttgatgca gaagaaatta
    10501 aaaatatgga tattagtgtt atagagacag cttcaagatt aggctatgat acaagtttat
    10561 atcgtccttt gtcagaaagt aaaaaggaaa tgtcattagg ataatatatt aattcaactg
    10621 aacaactttt agaaaataac agaatttcgc aagggaagta tgaggaactg ttactagatg
    10681 ctttcagata tgatattgta tatgggctag atgaagaggg gggagttgtc gtttgactag
    10741 tcgtgtattt attgatgcag attgtatttc agtattttta tgggttggca ctgaacatct
    10801 tttagaaaag ctctattcgg gtaaaattgt tattccacaa gaggtgtatg atgaaatcaa
    10861 tatacctaca attccccatt taaaatctag gatagaccag ttggtagcta agggttcagc
    10921 tgagattgtg agcatagaca ttggaactga agaatacgca ttatatagag atttaacaag
    10981 aaatcatgat agtaacaaga ttattggtaa gggagaagcg gcttctattt ccttagcgaa
    11041 aaagcataat gggatattag gaagtaataa cctaagagat gttaaatcat atgtagaaga
    11101 attttcttta gaacatatga caacaggaga tatactgatt gaagcgttta aagtgtaatt
    11161 tattactgaa caagagggca atcatatctg gaataatatg cttaaaaaga gaaggaaaat
    11221 tggtgcaaat tcattttcag actatcttcg tggaagtatt catcaaaata gacaaaaata
    11281 aatttggata aatcgaactc actattcagg aggcatatga gcaattcgaa aaagaaaagt
    11341 gtcaaattga gcctatagga gtagaagtga aatagtaagt cctgcatagt ggatgagaga
    11401 aaagttctcc ttgaagtttt cctgaactat cagtcgcatg tcaaacgata tgtagggtaa
    11461 tgtgagaggg gatagcgagt agtttttggt tattttatca aaaaacttat attttattat
    11521 accgaatgat aaaatataat aaaaatgata gaataaggaa aaaacatgaa tgtcaaaaag
    11581 ataatgtcaa tttttcaatc cttttatgtt gatgtcagta ttgaggaact gactttgact
    11641 ttaccaatca gttttgtaaa aaggtttgag tatactcaaa tgacttttca taaggaatca
    11701 tttttattga ttaaagaaaa gagaaggggg agtttgagtt catttgttac tcaggctcgc
    11761 actatgggtg aaaaagccaa tatggatgtt gttttggtgt tttcgaagtt atcagacagt
    11821 gaaaaaaagc aattacttca agctagagtt ccgtttgtag actttaaggg aaacctcttc
    11881 ttccctccat tgggactagt actgaatgcg aatgatactg aagtccctaa ggaattaaca
    11941 cctagcgaac aattaacgtg gattgccttt ttattgacaa aaggtcaaaa agtagtagat
    12001 gttgatttgc tttcacaagt cactggactt ccaaactcaa caatttatag gtgtttgagg
    12061 acttttaaag ctttatattg gttaaacaag caaaataagc tttacacata tacggtgtca
    12121 aagaaagaat tattcttaaa atccgtgtca tgtttattta atcccatcaa aaaacggatt
    12181 ttattgccag atggcgatat aaagcagata aaatctgttt ctaatcttct atatggtggt
    12241 gcttatgctt tgtcgcattc aactttttta gctgaaacgg atgaaaatat tagctatgtc
    12301 atatggcaga gaaaattcaa tcagttatcc ttgccacttt ctcagcatgt tttaaaagga
    12361 aagatgctag agatatggaa atatcgtcct tttgtatctg agttttggaa tgattttaaa
    12421 aataatcatg ataaacaatt tgtagatccg atttctcttt atttgacctt aaaagatgat
    12481 gatgacccac gtatagagga agagagtgaa gcactagaaa atatgatatt acagtatctg
    12541 ggagaagatg atgccagcta atacgaaagt tatttttcaa gaaatgtttg cggattttca
    12601 gaactattat gttctgattg ggggaactgc tacctctatc gtattggatt cgcaaggatt
    12661 taaaagtcgc acaacaaaag attatgatat ggtcatcatt gatgaagtaa aaaataagga
    12721 attttatact accttgaatc attttttaga attgggagag tatcaaggaa gtcagaaaga
    12781 tgagaaagcg cagctttttc aatttacaac aactaatcct gagtttcctt ctatgattga
    12841 actatttagt atcttaccag aatatccatt aaagaaggac ggtcgagaaa ttcccttata
    12901 ttttgatcaa gatgctagtt tatcagcctt attattggat gaagattatt ataatatatt
    12961 ggtgcatgta aaagaaacca ttcaggggta ttcggtattg agtaattgtg gtc
//
LOCUS       DAVLDI010000064        12336 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLDI010000064 DAVLDI010000000
VERSION     DAVLDI010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12336
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.064"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(88..555)
                     /locus_tag="VXD01_001901"
     CDS             complement(88..555)
                     /locus_tag="VXD01_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602243.1"
                     /translation="MDLLEKECLKCDKNFQQGDIWNYYYLSDKVPAQGWKIHISSQIK
                     DAVNIFKIVYKLSQLNNCSFKVVKNLEELKKINSPREMSPTANKFITLYPKSESEAKS
                     MICNLTNKLSEFKAPKILSDYQCGMHSPVHYRYGAFLKKQAYDEKIKKSSIYC"
     gene            1095..1772
                     /locus_tag="VXD01_001902"
     CDS             1095..1772
                     /locus_tag="VXD01_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV0602244.1"
                     /translation="MISKRLELVASFVPQGAILLDVGSDHAYLPIELVERGKIESAIA
                     GEVVEGPYQSAVKNVEAHGLEEKIQVRLANGLAAFEEEDRVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            1759..2556
                     /locus_tag="VXD01_001903"
     CDS             1759..2556
                     /locus_tag="VXD01_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV0602245.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLEIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            2573..3676
                     /locus_tag="VXD01_001904"
     CDS             2573..3676
                     /locus_tag="VXD01_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV0602246.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYAVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            3683..3829
                     /locus_tag="VXD01_001905"
     CDS             3683..3829
                     /locus_tag="VXD01_001905"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602247.1"
                     /translation="MKIKEQTRKLAADYSKHCFEVVDRTDEVSNHTHGKATLTWFELD
                     FRRV"
     gene            3932..4951
                     /gene="galE"
                     /locus_tag="VXD01_001906"
     CDS             3932..4951
                     /gene="galE"
                     /locus_tag="VXD01_001906"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV0602248.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGIIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLKIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            4953..5906
                     /locus_tag="VXD01_001907"
     CDS             4953..5906
                     /locus_tag="VXD01_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0602249.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(5968..6174)
                     /locus_tag="VXD01_001908"
     CDS             complement(5968..6174)
                     /locus_tag="VXD01_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV0602250.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            6226..6702
                     /locus_tag="VXD01_001909"
     CDS             6226..6702
                     /locus_tag="VXD01_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV0602251.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            6711..7382
                     /locus_tag="VXD01_001910"
     CDS             6711..7382
                     /locus_tag="VXD01_001910"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV0602252.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYIDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            7513..7851
                     /locus_tag="VXD01_001911"
     CDS             7513..7851
                     /locus_tag="VXD01_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV0602253.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            7854..8483
                     /locus_tag="VXD01_001912"
     CDS             7854..8483
                     /locus_tag="VXD01_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV0602254.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            8723..9874
                     /locus_tag="VXD01_001913"
     CDS             8723..9874
                     /locus_tag="VXD01_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0602255.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            10192..10941
                     /gene="truA"
                     /locus_tag="VXD01_001914"
     CDS             10192..10941
                     /gene="truA"
                     /locus_tag="VXD01_001914"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV0602256.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVAADFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            10931..11704
                     /locus_tag="VXD01_001915"
     CDS             10931..11704
                     /locus_tag="VXD01_001915"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV0602257.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            11682..12143
                     /locus_tag="VXD01_001916"
     CDS             11682..12143
                     /locus_tag="VXD01_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV0602258.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNDWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         3518 a         2310 c         2763 g         3745 t
ORIGIN      
        1 cttcttctga aaataaatcc attttccagc taggaagact agggaaattt tgtctcttat
       61 cttctacata gttcttcctt ttttcatcta gcaataaata gatgactttt ttattttttc
      121 atcataagct tgttttttta aaaaagcccc atatctataa tgaactggag aatgcattcc
      181 acattgatag tcagatagta tttttggagc cttaaattct gacagtttat tcgtaagatt
      241 acaaatcata ctcttggctt cagattctga cttaggatat agagttataa atttgttagc
      301 agtagggctc atttccctag gggaattaat tttttttaat tcctctaaat ttttaacgac
      361 tttaaagcta caattattta gttgggatag tttatacaca atcttaaaaa tatttacagc
      421 gtcttttatt tgggagctta tgtgtatttt ccagccttgt gcaggcacct tatctgataa
      481 ataatagtaa ttccaaatat caccctgttg gaaattttta tcacatttta aacattcttt
      541 ctctaataaa tccataacaa actcctaatt attaaaatag gctagagaca cagcactagc
      601 ctattccgta agtaaagcta cttattttat ataaaatata actagcgacc tgtaattaaa
      661 caagtaaaag aacaatactt agggagacct gtgacaatga catcttcctc tggaagtagt
      721 tctaattcaa acaatgtttg ttccatgact gtatcctcct gttatgataa attccagaaa
      781 gcatagagca aattcgtggt tcgtctgact aaatttctta tctgaacacc accttcaaat
      841 acaaatttta gtcaaacttt tattttttct aactttctaa ttatattcta ccatgtgttt
      901 ttatatgtca agaattttct gaataaactg tttatttttt attttttgca aattgtttaa
      961 aatctttcaa ttggattcac ttattacttt aggacattga aacttctttc gccagaggtg
     1021 cttatattac tgggaagttg aagattgaaa tgtggtataa taagaggtaa tagagttttg
     1081 gaaagagaga gaagatgatt tcaaagagat tagagttggt agcttccttt gtgccgcagg
     1141 gagccatttt actagatgtg gggagtgacc atgcttattt gcctatagag ttagtcgaaa
     1201 gaggaaaaat cgaaagtgcc attgcaggtg aagttgtgga gggaccttat cagtctgctg
     1261 tcaaaaatgt tgaggcccac ggcttggaag aaaaaatcca agtccgttta gccaatggtt
     1321 tggcagcttt tgaagaggaa gaccgagtgt ctgtcattac cattgctggc atgggtggtc
     1381 gtttgattgc taggatttta gaagaaggtt tggggaagtt agctaatgta gagcgtttga
     1441 tcctccagcc caataatcgt gaagacgact tgcgtatctg gctacaggat catggattcc
     1501 agattgtagc agaaagcatc ttagaagaag ctggaaagtt ttatgagatt ttggtggtgg
     1561 aagcaggaca aatgaagcta tcagccagtg atgttcgctt tggtcccttc ttgtccaaag
     1621 aagtcagtcc agtatttgtc caaaaatggc aaaaagaagc tgagaagcta gagttcgccc
     1681 tcggacaaat cccagaaaaa aatctggaag aacgtcaagt tctagtagat aagattcaag
     1741 ctatcaagga ggtgctccat gttagcaagt gaagtgatcc aagcttatga agccttttgc
     1801 cctcaggaat tttctatgga gggagacagc cgtggtctgc aaattggcac tttagacaag
     1861 ggtatccaaa gggtcatggt tgccctcgat attcgtgaag agacagtggc agaggccatt
     1921 gaaaagggtg tggacttgat tatcgtcaag cacgcgccta tctttcgtcc tatcaaggac
     1981 ttgcttgcca gccgtccgca aaatcagatt tacatcgacc tgattaagca tgacatcgca
     2041 gtttatgtca gccataccaa tattgatatc gttgaaaatg ggctcaatga ctggttttgt
     2101 cagatgctag aaatcgagga gacgacttat ctgcaggaaa caggtccaga acgtggaatt
     2161 ggacgtattg ggaatattca gcctcagaca ttttgggaat tggcccaaca ggtcaagcaa
     2221 gtctttgacc tagatagcct tcgaatggtg cattatcaag agaatgattt gcagaagcct
     2281 atttcaagag tagcaatttg tggtggaagc gggcagtctt tctataagga tgctttggca
     2341 aagggggcag atgtctatat cactggtgat atctactacc atactgctca ggatatgctg
     2401 tctgatggct tgttagcatt ggatccaggt cactatatcg aagtgctttt tgtggaaaaa
     2461 atcgcagcac tccttactca atggaaagag aaaaaaggct gggaactaga gattttacct
     2521 agtcaagcat cgaccaatcc tttccgtcat atctagttag aaagtgaaga caatgaaaaa
     2581 agttgccatt attggagcag gaattgtggg agcaacagct gcctactacc tctcgagaga
     2641 aagtgaccta gaggtgaccg tttttgacca tgagcaaggt caagccacca aggccgcagc
     2701 aggaattatc agtccttggt tttccaaacg ccgtaataaa gcctggtaca agatggcgcg
     2761 cttgggggct gatttttatg tggatttatt agctgattta gagaaatcag gacaaaaaat
     2821 cgacttttac cagcgttcgg gagtctttct cttgaaaaag gatgaatcca agttggaaga
     2881 actttatcaa ctggccctcc agcgcagaga agaatctccc ttgatagggc aattagccat
     2941 tctggaccaa gcctcagcta atgaattatt ccctggtttg cagggatttg accgcctgct
     3001 ctatgcttct ggtggagcga gagtagatgg ccaactcttg gtaactcgtc tgctagaagc
     3061 cagtcatgtc aagctggtca aagaaaaagt gactctgaca ccgttagcat caggctacca
     3121 gattggtgaa gaggagtttg agcaggttat tttggcgacg ggagcttggt tgggggacat
     3181 gttagagcct ttaggttatg ctgtggatgt ccgtcctcaa aaaggacaac tacgagatta
     3241 tcagctggtc caagatatgg aagcttaccc tgttgtcatg ccagaagggg agtgggattt
     3301 gattcctttt gcaggtggga aattgtcctt aggcgctacc cacgaaaatg acatgggatt
     3361 tgatttgacg gtagatgaaa ccttgctcca acaaatggag gaggccacct tgactcacta
     3421 tctgattttg gctgaagcta cttcaaaatc tgagcgtgtt ggaatccgtg cctacaccag
     3481 tgatttctct cctttctttg ggcaggtgcc tgacttaact ggtgtctatg cagccagtgg
     3541 actaggttca tcaggcctca caactggtcc tattattggt taccatttag ctcaactgat
     3601 ccaagacaag gagttgacct tggaccctga aaactaccca attgaaaact atgtcaaacg
     3661 agtaaaaagc gaataatact caatgaaaat caaagaacaa actaggaaac tagccgcgga
     3721 ttactcaaag cactgctttg aggttgtgga tagaactgac gaagtcagta accataccca
     3781 tggcaaggcg acgttgacgt ggtttgaatt ggattttcga agagtataag cattttactg
     3841 aaattttatc aggtagttta ggatggcaaa tgacattccc tgtcaaaaat ggtaaaataa
     3901 gaaaaaataa tctgagaatc gaggaaaaaa gatgcaagaa aagattttgg taactggtgg
     3961 tgccggtttt attggaaccc acactgttat tgaattgatc caagcaggcc atcaagttgt
     4021 tgtggtggat aatcttgtca atagcaatcg taagagttta gaagttgttg aaagaatcac
     4081 aggagttgag attcctttct atgaggcaga tattcgtgac acagataccc tcagagatat
     4141 tttcaagcag gaagaaccga ctggtatcat tcactttgct ggtttgaagg ctgttggcga
     4201 atcaacacgt atccctcttg cctactatga caacaatatc gctggaactg tcagcctttt
     4261 gaaagccatg gaagaaaaca actgtaaaaa catcatcttc agttcttctg cgacagttta
     4321 cggggatccg cacacagtgc ccatcttgga agatttccca ctttcagtga ccaacccata
     4381 cggtcgtacc aagctcatgc tagaggaaat tttgaccgat atttacaaag cagactcaga
     4441 atggaatgtt gtcttgcttc gttactttaa cccaatcgga gcccatgaga gtggtgattt
     4501 gggagaaaat ccaaacggta ttccaaacaa tctcttgcca tatgtgactc aagtagccgt
     4561 tggaaaatta gagcaagtgc aagtgtttgg agacgattac gatacggaag atggaacagg
     4621 tgttcgtgac tatatccacg ttgtcgattt ggctaagggt cacgttgcag ctttgaaaaa
     4681 aatccaaaaa ggttcaggac taaacgttta taaccttgga actggtaaag gttactcagt
     4741 tcttaaaatt atccaaaaca tggaaaaagc ggtgggacgt cctattcctt accgcatcgt
     4801 agaacgtcgc ccaggtgata tcgctgcctg ctactcagac ccagcaaaag ctaaagcaga
     4861 actcggttgg gaagcagaac tcgacatcac ccaaatgtgt gaagacgcat ggcgttggca
     4921 aagcaagcat ccaaatggat ttgaagacta agatgatgat ttcaatcatc gtcccttgtt
     4981 taaacgaaga ggaagtactt cctctttttt atcaggctct ggaagcttta cttccagatt
     5041 tggaaacaga aatcgagtat gtctttgtcg atgatggatc aagtgatggg accttggaac
     5101 tcttaaaggc ctatcgggag caaaatccgg cagtccatta tatttctttc tctcgaaatt
     5161 ttggcaaaga agcagccctt tatgcaggct tgcaatatgc gacaggagat ttggtggtgg
     5221 tgatggatgc agacctccaa gatcctccta gtatgttgtt tgagatgaaa aatgtactag
     5281 acaaaaatgt agacttggac tgcgttggga cacggagaac tagtcgggag ggagaaccct
     5341 tctttcgcag tttctgtgct gttctctttt atcgcctcat gcaaaaaatc agcccagtag
     5401 ctctgccgtc gggtgtccgt gattttcgta tgatgagaag gtctgtggtc gatgccattt
     5461 taagcttgac tgagtccaat cgtttttcta agggactctt tgcctgggtc ggctttaaaa
     5521 cccactatct ggactatcca aatgtcgaaa ggcaggctgg caagaccagt tggagtttta
     5581 ggcaactctt tttttactcc attgaaggga ttgttaattt ttcagatttc cctttgacta
     5641 tagcctttgt agctggtctc ctatcttgtt ttctttctct gctgatgacc ttttttgttg
     5701 tggttcggac cctcattttg ggcaatccga catctggttg gacctctctg atggctgtta
     5761 ttctctttct tggaggcatt caactcttga ccattgggat tctcggtaag tatatcagta
     5821 agatttattt agagactaaa aaaagaccac tttatcttat caaagaaaaa agtgaccttc
     5881 ctgattttac agaaaaaata aagtgaaaag actataattt tacatggaaa tgtgctaaac
     5941 tagagggagt ggattatcgc cattgattta ggcttcctgg tttccaatca gggcgcgagt
     6001 tgggcaattt ttaacagcct ctaagacatc ctgactagga gaaatttctt tttccagttg
     6061 gtcagggtca tcgtaaaaac gcacgattcc attatcgtgg taatcaaata aatcagaata
     6121 agtttggcaa agtccacagg cgatacatcg ttcaggtata agtgtgattt tcatgttcat
     6181 atttatattg taataagaaa agtaaaaaaa aacaaggagt aaggtatggc aaaagaaccg
     6241 tggcaagaag atatttatga tcaagaagaa tcaagagcag ggcgtcggca tcgaaaccac
     6301 ggaggggctg ataggatggc taatcgtatt ttgacgatcc tagctagtat tttctttgta
     6361 attgtggtgg tgatggtcat cgttctcatc tatctatcat cgggggggag caatcgcaca
     6421 gcagccttaa aagactttca tgattctgat gcaagtgtag tacaaatctc atcttcaagc
     6481 agttctcagc ctgagcagag ttcagagcca gaatctactt ctagtagttc agaagaagct
     6541 gctaatcctg aaggaacgat taaagttctc gcaggagaag gggaagcagc tattgccgct
     6601 cgtgcaggaa tctccattgc tcagttagag gccttgaatc ctgggcacat ggctacagga
     6661 tcttggtttg ctaatccagg tgatgttata aaaataaaat aggagccgat atgaaaacaa
     6721 ttcaaattgc tattgatggt cctgcttcca gcggtaagag tacggtcgca aagattattg
     6781 ctaaggattt tggattcacc taccttgata caggagctat gtatcgtgca gcgacctata
     6841 tggctcttaa gaaccaatta ggagttgaag aagtcgaagc ccttctagcc ttgttggacc
     6901 agcatccaat cagctttgga cgttcagaaa ctggagacca gcttgttttt gtaggagatg
     6961 tggatattac ccatcctatc cgtgaaaatg aagtgaccaa tcatgtttct gctattgcag
     7021 caattcctga agtgcgtgag aaactggttt ctctccaaca agaaattgcc cagcaaggcg
     7081 ggattgtcat ggatggtcgc gatattggaa ctgttgtatt gccacaagca gaattgaaaa
     7141 ttttcctagt agcttctgtt gatgagagag cagagcgtcg ttacaaggaa aatattgcca
     7201 agggaattga aacagacctt gaaaccctaa aaaaggaaat tgctgcgcgt gactacaagg
     7261 atagtcatcg tgagacttct cctctcaaac aagcagagga tgctgtctac attgatacaa
     7321 ctggtttgaa cattcaagaa gtagttgaaa aaatcaaagc agaagctgaa aaaagaatgt
     7381 aaatgtagaa aagccgatag attgatatcg gtttttttct aaatttgtca aaatgctgat
     7441 tttagggtat aatagttgct gttcgagaaa ttttgatttt caaagaatag tgaatgatga
     7501 taaggagaaa ccatgaacaa tttaccaaat tgtccaaaat gtaactcaga gtatgtctac
     7561 gaagacggtg ccctactggt ttgcccagag tgtgctcatg agtggaatcc tgctgaagtt
     7621 gcagaagtag aagaaggtct tgtcgctatc gatgccaacg gaaataaatt gactgatggt
     7681 gatacagtaa ctctcatcaa ggacttgaaa gtaaaaggtg cgccaaaaga tttgaaacaa
     7741 gggacgcgcg tgaaaaatat ccgcatcgta gaaggcgatc acaatatcga ctgtaagatt
     7801 gatggttttg gtgccatgaa acttaaatca gagtttgtga ggaagattta agcatgtcaa
     7861 aacactataa acttgtattt tatagccgta tcttcttgtt tctagcggct tttacgggag
     7921 tttatcttga aattactagg catggtggtt ttgggatgct tctctattac acggttctgt
     7981 ccaacctctt ggtaactatt tttacccttt atcttctaaa ggttatgagc cgtgtaggtg
     8041 aaaattggca aaggccaagt ctcttgcgct taaaaggtgg ggtcaccatg agtatcatga
     8101 ttacctgtgt gatttaccat ttcctcttgg cgcccattgc gactaatttc tataccctag
     8161 aaaatttcct ttgccactat atcgttccca tctggttttt agcggatacc ctcttttttg
     8221 acaaacaggg tcaatacaag atttgggatc cagcagtgtg gaccatttta ccctttctgt
     8281 atatgatgtt tgctcttttt aatggcttgg ttctaaaact caatattcca aatgccaagg
     8341 ataatccttt cccttacttc tttttgaatg tgaacaaggg ttggaatgtt gtgtttaagt
     8401 ggtgtctgat tatctttgtt gcctatatgg tagcaggatt tattttctac tttatcaagc
     8461 aaatcaagag aaagtcatcc taatactctt cgaaaatctc ttcaaaccac gtcagtttcc
     8521 atctgcaacc tcaaaacact gttttgaaca acctgcggct agcttcctag tttgctcttt
     8581 gattttcatt gagtataaga tacaagggat tcattttcga atttaagaag gagtctacaa
     8641 accaatgagg cttcttcttt tcttgcttat ttgataacta tcaaaaaagt agaagattaa
     8701 gagaaatata gaaagagatt tcatgaaaca atttttagaa cgggccagca ttttggctct
     8761 ctccctcgtt ttgattacct ccttttccat ttcgagtgcc ctaccagcca tgtttgacta
     8821 ttatcagggt tattctaagg aacaaattga gctcttggtg agcttgcctt cctttggaat
     8881 catgatgatg ttactgctaa atggtttctt agaaaaaata tttcctgagc gcttacagat
     8941 tagtttgggc ttgctgattt tatcattgag cggtacagct cccttctggt accaagccta
     9001 tccctttgtc tttggaacac ggcttctctt tggtttgggt cttgggatga tcaatgccaa
     9061 ggccatttct attatcagtg aacgctacca aggaaaaagg cgaattcaga tgttagggct
     9121 acgcgcttct gcagaggtcg ttggagcttc tctcattacc ttggccgtcg gtcagttgtt
     9181 ggcctttggt tggacagcta tctttctagc ctatagtgct ggatttttgg tgctgcccct
     9241 ttatctgctc tttgtccctt atggaaaatc aaagaaagaa gtcaagaaaa gagcgaagga
     9301 agcaagtcgt ttaactcgag aaatgaaagg cttgattttt accttagcta tcgaagcggc
     9361 agttgtagtt tgtaccaata cagctattac catccgtatt ccaagtttga tggtggaaag
     9421 aggattgggg gatgcccagt tatctagttt tgttcttagt atcatgcagt tgatcgggat
     9481 tgtggctggg gtgagttttt ctttcttgat ttctatcttt aaagagaaac tgctcctctg
     9541 gtctggtatt acctttggct tggggcaaat cgtgattgcc ttgtcttcat ccttgtgggt
     9601 ggtagtagca ggaagtgttc tggctggatt tgcctatagt gtagtcttga cgacggtctt
     9661 tcaacttgtc tctgaacgaa ttccagctaa actcctcaat caagcaactt catttgctgt
     9721 attaggctgt agtttcggag cctttacgac cccattcgtt ctaggtgcaa ttggcttact
     9781 aactcacaat gggatgttgg tctttagtat cttaggaggt tggttgattg taatctctat
     9841 ctttgtcatg tacctacttc agaagagagc ttaggattga ttcctaagtt tttcttttga
     9901 tactcaatga aaatcaaaga gcaaactata gttgattgag tttggaatag tacgctgtag
     9961 ctgctaaaat atttctagaa attaatttga ctttcctaat agagttgttc atatcttatt
    10021 tcaatctact atagaaagct agccgcaggt tgctcaaaat agtgttttga ggttgcagat
    10081 ggaaactgac gtggtttgaa gagattttcg aagagtatga gatttttata cccatacaat
    10141 atttgtttta ggtccttgtt tacagactaa tttcttgata aaatagaggt tatgacgaga
    10201 tataaagcaa ctatttccta tgatggttat gcctttgctg gctttcagcg ccagcctcat
    10261 gcgcgtagcg ttcaggaaga aattgaaaaa accttgacca gattaaataa agggcaaacc
    10321 attactgttc acggtgctgg taggacagat agtggggttc atgccctggg acaggtcatt
    10381 cattttgacc tgccttatca gatggatgag gagaaactcc gttttgcctt ggatacccag
    10441 tctcctgaag atattgatgt gatttcgatt gagcttgtgg cagctgattt tcattgccgt
    10501 tatgccaagc atagcaagac ctatgagttt attgtggata gaggacgtcc caaaaatccg
    10561 atgcgccgtc actatgccac ccactttccc tacccactcg atgtggaacg aatgcagatt
    10621 gcaatcaaaa agctagaggg aacccatgat tttaccggtt ttacagcctc tgggactagt
    10681 gtagaggata aggttcgcac catcacagaa gctagtttaa tagtcgatga gacaggacaa
    10741 tttttgacct ttaccttttc cggaaatggt ttcttgtata aacagattcg caatatggtg
    10801 gggactcttc tcaaaatcgg taacaaccgc atgccagtag agcagattga tctcatcttg
    10861 gagaagaagg acaggcaact tgcaggtccc actgcagcac caaatggttt gtatttaaag
    10921 gagattcgtt atgaagaata atcgtatttt agcactttct ggaaatgata tttttagtgg
    10981 tggtggactg tcagctgatt tggctaccta taccttgaac ggcttgcatg ggtttgtagc
    11041 agtgacttgt ttgacagcct tgacagaaaa aggatttgaa gtctttccaa ctgatgatac
    11101 catttttcaa catgaattag atagcttgcg tgatgtggaa tttgggggaa ttaagattgg
    11161 tcttctccct actgtcagtg tggctgagaa ggccttggac tttatcaaac aacgcccagg
    11221 agtacctgtg gtgttggatc ctgtcttggt ctgcaaggaa acgcatgatg tagctgtcag
    11281 tgagctctgc caagagttga ttcgcttttt cccttatgtc agtgtgatta cgcctaatct
    11341 cccagaagca gaattattat ccggtcagga aattaaaacc ttggaagaca tgaaaactgc
    11401 agcgcagaaa ttgcatgatt taggagcgcc agcagtcatt atcaagggag gcaatcgtct
    11461 tagtcaggac aaggctgtgg atgtctttta tgatggacag acctttacta tcctagaaaa
    11521 tccagttatc caaggccaaa atgctggtgc aggttgtacc tttgcctcta gcattgccag
    11581 tcacttgatt aaaggtgata aacttttgcc agcagtagaa agctctaagg ctttcgttta
    11641 tcgtgctatt gcacaagcag atcagtatgg agtaagacaa tatgaagcaa acaaaaacaa
    11701 ctaaaatcgc ccttgtatcc ctattaaccg ccctttctgt ggttctaggt tatttcttaa
    11761 aaatcccaac acctacagga attctaactc ttttagatgc tggtgtcttc tttgcggcct
    11821 tttactttgg tagtcgtgaa ggagcggtag tcggaggact agcaagtttc ttgattgacc
    11881 tcttatcagg ctaccctcag tggatgttct ttagcttggt caaccatggc ttgcagggat
    11941 ttttcgcagg atttaaagga aaaagtcagt ggttaggcct tattttagca actattgcca
    12001 tggtaggagg ctacgccttg ggttctactt tgatgaatga ctgggcagca gccctcccag
    12061 aaattctacc aaatttcatg caaaatatgg tagggatgat tgtaggattt attcttagtc
    12121 aaagtatcaa gaagattaag taatactctt cgaaaatctc ttcaaaccac gtcagcttgt
    12181 ccttagtgtg tatatgttac tgacttggtc agttctatcc ttaacctcaa aactatgttt
    12241 cgaggagcct tccgctaact tcccagtctg agtttcattg aatattaacg atactttatc
    12301 acataaagag gctggatgaa aagtcttcac aatcaa
//
LOCUS       DAVLDI010000065        12293 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLDI010000065 DAVLDI010000000
VERSION     DAVLDI010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12293
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.065"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            11..295
                     /locus_tag="VXD01_001917"
     CDS             11..295
                     /locus_tag="VXD01_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602259.1"
                     /translation="MVWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            288..536
                     /locus_tag="VXD01_001918"
     CDS             288..536
                     /locus_tag="VXD01_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602260.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            632..850
                     /locus_tag="VXD01_001919"
     CDS             632..850
                     /locus_tag="VXD01_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602261.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(1218..3542)
                     /gene="pflB"
                     /locus_tag="VXD01_001920"
     CDS             complement(1218..3542)
                     /gene="pflB"
                     /locus_tag="VXD01_001920"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV0602262.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            3937..4998
                     /gene="dinB"
                     /locus_tag="VXD01_001921"
     CDS             3937..4998
                     /gene="dinB"
                     /locus_tag="VXD01_001921"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV0602263.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(5145..5990)
                     /locus_tag="VXD01_001922"
     CDS             complement(5145..5990)
                     /locus_tag="VXD01_001922"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV0602264.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTNRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            6246..7196
                     /locus_tag="VXD01_001923"
     CDS             6246..7196
                     /locus_tag="VXD01_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEV0602265.1"
                     /translation="MLYVGIDVAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     FRQLNQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYTPLLIKEFAKSLSLRKTKTDKK
                     DAHGIALKLLSDPNREQFQHDNRQIELKILARHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVGKHSEYTYQLLTRYPNPQKRLEAGFDKLIEIKRLTASKIQDILSVAPRSIGTT
                     SPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVILAEIRNI
                     HAFDNPAQLQAFAGLDSSIYQSDQIDLAGRMVKRSSPHLR"
     gene            complement(7575..9464)
                     /locus_tag="VXD01_001924"
     CDS             complement(7575..9464)
                     /locus_tag="VXD01_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV0602266.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVMDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRGA
                     KAADEKRIQARGIQLKSSFEAVLKEMQEGVRKRVVFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            9602..11167
                     /locus_tag="VXD01_001925"
     CDS             9602..11167
                     /locus_tag="VXD01_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV0602267.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTITGLIIGLAIGVFRTAPLSENKVIYS
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            11167..11907
                     /locus_tag="VXD01_001926"
     CDS             11167..11907
                     /locus_tag="VXD01_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV0602268.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(12016..12231)
                     /locus_tag="VXD01_001927"
     CDS             complement(12016..12231)
                     /locus_tag="VXD01_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602269.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
BASE COUNT         3824 a         2578 c         2339 g         3552 t
ORIGIN      
        1 gaggaagaca atggtttggt acgattatat gatacaggca tccaaacaat cacaattcaa
       61 cgcaagccat tggtttcgct atttgcgaaa agttattttt gaagactatt cttatttaac
      121 aaaccaagat gtagaaaagt tgctagactc caaagaacta acccgttttc aaaaaattag
      181 cttgaagtat gcctttcaag agcatactcc aactcataaa tatgtgattt cattaaataa
      241 acctgctaag ttaaccaatg ttcaaaaatt gatggagaaa tacaaacatg gataaaatga
      301 aaccggtctt ccaagcccta aataaggaat taattcagga aaatctgact ttaacaatta
      361 tctgtgtcga tggttatgtc ttagaatatc atggtttacg tgccacacaa gatgttgatg
      421 ctttttatga ccaaaatcag aaaatcaatg aaattattgc tcgtgtagga aaacagttta
      481 atcttaacat ccacgaagag ttatggctca acaatcatgt tgcaaagcaa atatgaacaa
      541 acaacctccc ttaagtttat gcgaatcctt gtactcattt gagaatctga ccgttttagt
      601 agtccctatt gagtatgtgt taggaatgaa gatgatgagt atcagagagc aggatttgca
      661 agatattggt gcaattatta aatacaaaaa ctttcattca ccattcgata cctttaaata
      721 tttaaaagac atgggatttg atactattga cctctctgtt ctattagaag gttttagtta
      781 tgcttatggt atggattggt tagaaaaatt ttttaaagaa aatcaagata aacttcgcga
      841 attttattaa cagtatcaaa caagatgatt gtcaattagc cagtcgtctt gttttttatg
      901 atgaaatgaa ataaaatctg aacaaatcgc ttagagaatt ccagtcaatt tctagcgctg
      961 tttgagacgt ttcagtggac tatagtaaaa tgaaataaga ataggacaaa tcgatcagga
     1021 cagtcaaatc gatttctaag aatgttttag aaataaaggt gtactattct agtttcaatc
     1081 tattatattt cagattcggt ccactattcc ttcccaaaaa cattgcatat tgcgccgaag
     1141 gaattgctca cactatccca agcacaaaac cctcagtcgt ttgaccgagg gttccttttc
     1201 attattcaag aacttgatta gctcaatgca tccaaggcgt catccattga aagaacttcg
     1261 tggaagacac gttgtgtcaa ttcagttttt tgttctggag tgaggtattt agtgtttaca
     1321 cagtatccag agatacgtac gataacgtct tcgcctgaca tgatcttttc gtaaacatcg
     1381 ttcaagtcca taacgttcaa gttaacgtgt tgtccaccgt tttcgaagta accatcaagg
     1441 attgttacca agttatcaac ttgttcatca cgagtcttac caagagcgcg aggtgatact
     1501 tgtgtagtca atgagatacc gtcagctgca taactaaagt caaggctaga aagtgagttc
     1561 aagttttgca accaaccacc tttagctttg ttagatgggt tagcacctgg tgagaagaat
     1621 tcaagtttag acaagttcac agaaccatct tcgttgaggt atacaccttt gtgaactggt
     1681 gagttaccag tttgtttaga gtaagcaacg ttagatgtga ttgtcaaaag tgatactgta
     1741 gcttctgcgt ctttgtatag tttgtggcta cgtagacgag ttgtgtaggc ttcgatcaac
     1801 cattctgcca attcgtttga acgtgggtca tcttcacccc agcgtgggta gtcaccgatt
     1861 gtttcgtaat cgtagatgta gccatcttcg tcacggattg gtttaactgt agcgtatttg
     1921 atagctgaca atgtatcaac agtgttagca aatccacaga taccgaatcc catgttggca
     1981 cgttgtttag ttggcaagaa ggccatttga acagcttcgt agttgtacct atcagtcatg
     2041 tagtggatga tgttcaaggc atctacgtaa gtgtcagtca accagtcaag agatttttca
     2101 aagttcgctt taactgattc gaattcaaga acttcgtcac ggattggttc gatatcaaat
     2161 actttgtagt ctttgtgaac atcgtcgtaa ccaccattca aaccagtaag aagggcttta
     2221 agaacgttta cacgagcacc gaagtactgg atgttgtggc gttgttcttc attttctgga
     2281 tcaagtggag acacacagca tgagatacag ctcatttcac catatccgtc tttagccatt
     2341 gttgttacac cttcgtattg gatagaagag tgtttgtggc tcatgtgcat acagtagcga
     2401 cggaagttgt atggcaattt gtcagtccaa agaactgtca agtttggttc tggtgagtta
     2461 ccgatgttgt caagagtgtt caagaaacgg tagtccatct tagtaacacg gtgacgaccg
     2521 tcgttaccca taccagccat agaagttgtg ataaaggttg ggtcacctga gtacaattgg
     2581 tcataagctt ttgtacgagc aaatttaact gtacgaagtt tcataacgaa atcatcaacg
     2641 aattcttgga tttctgattc agtaaatgta ccacgagcaa ggtcacgttc tgcaaagatg
     2701 tccaatacga ttggtacacg acctagagat gtagcagcac cgttaatcac acggcagaca
     2761 gccatgaaag caatgttaac ccattggatt gcttctttca cgttcatcgc tggtttgcga
     2821 acatcaaccc cgtaaaggtc acccaggcga acaacttgtt gcaatgcttg gtattgaagg
     2881 tttacttctt cacgaagacg gattgtttct tcatcgattt ctttgattgc attccagtcg
     2941 tttacttttt cttgcatcaa gtagtctgca ccgtaaagag caagacgtgc gtaaacaccg
     3001 atgatacgtc cgcgtgagta tgcatctgga agaccagtta cagtgtgtgc gtgacgagcg
     3061 cgacgaatat ttgaagtgta ggcacggaaa ataccgtcgt taactgttgt tacatattta
     3121 gtgaagattt cgtgaacagc tgggtctggt tcgtatccat tttcttttaa agtagtttca
     3181 gccatacgga taccaccttt tggcatgaag ttcaatttga agagttcatc attttggata
     3241 ccaaagataa cttcattttc tttgtcgata aatccagcag ggatatcagc gatagatgtt
     3301 ggacgagtgt ccattgggaa acgagtttct tcgtagtgtg ctttagtttc ttctacaatt
     3361 ttcttgatgt gaagtgaacg ctctgttggt cctgcaagga agctttcgtc tccatcataa
     3421 ggtgtgtagt tagcttgtac aaagcgtgat acacttgctt tttctttcca atctacgcct
     3481 ttgaagcctt cccaagcttt gtcaaaaata tcttgtgctt caacaactgt cttaacaacc
     3541 atattaatgt cctctttttt ctagtaacag tcatctgtta cattcataag acaagtatac
     3601 cataaagtaa ccgatttcaa caagtgcaaa atccctattt ttacactttc ttttctaaaa
     3661 cagtctatat tttatttcaa actgtattat atttttgaaa aaaataaagt ccttttttct
     3721 ttttttcaga aaaaagggta taataaaaga aaataagcag taacactcaa tggaaatcga
     3781 aaagcaaact aggaagctag ccgcaggctg ctcaaagcac tgctttgagg ttgtaaatag
     3841 aactgacgaa gtcagctcaa aatactgttt tgaggttgca gatggaagct gacgtggttt
     3901 gaagagattt ttgaaaagta taaaaaggtg ctaggcatgt tgatttttcc tttgttaaat
     3961 gatttgtcaa gaaaaatcat ccatattgac atggatgcct tttttgctgc ggtggaaatc
     4021 aaggataatc ctaaactcag aggaaaacct gtcattattg gaagcgaccc tcgacaaaca
     4081 ggtgggcggg gagtcgtttc tacctgtagc tatgaggctc gagcttttgg tgtccattct
     4141 gccatgagtt ccaaggaagc ttatgaacgt tgtccccagg ccgtctttat ctcaggaaat
     4201 tatgagaaat acaaagctgt gggactccag attcgagcta tttttaagcg ctatacagat
     4261 ttgattgaac ccatgagtat tgacgaagcc tatttggatg tgacagaaaa taaactcggt
     4321 atcaagtcag cggtcaaaat tgctcgcctc attcaaaaag atatctggca agaactccat
     4381 ctaactgctt ctgccggtat ttcctataac aagttcttag ctaaaatggc gagtgattat
     4441 caaaaacctc atggtttgac agtgattcta cctgaacagg ctgaggattt tctcaaacaa
     4501 atggatattt ccaaatttca tggagtagga aaaaagacag tagaacgtct tcatcaaatg
     4561 ggcgttttta ctggtgctga tttacttgaa gttcctgagg tgaccctaat agaccgtttt
     4621 ggtagactag gctatgatct gtatcgaaag gctcgtggca ttcacaactc tccagtcaaa
     4681 tccaatcgca tccgtaaatc aatcggcaag gagaaaacct acgggaagat tctccgtgct
     4741 gaggaagata tcaaaaaaga gctgactctt ctatcagaaa aagtcgctct caatctacat
     4801 caacaagaaa aagctggaaa aattgtcatt ttgaaaatcc gctacgagga cttttcaact
     4861 cttaccaaac gaaaaagtct tgctcaaaaa acacaagatg ctagtcagat aagccaaata
     4921 gccctgcaac tctatgaaga attaagcgag aaagaaagag gtgtccgcct attggggatt
     4981 accatgactg gattttaaag ctcaatgaaa atcaaagagc aaactaggag gctagccgca
     5041 ggctgctcaa aacactgttt tgaggttgca gataaagctg acgcggtttg aagagatttt
     5101 ctaagagtat aaaaccttga agagttgccc cttcaaggtt tttcttatac aaataaacgg
     5161 acaaaactgt aaagtagcaa aacactacca agcacgatac ggtatttacc aaaaagggtg
     5221 aagtcgtgtt ttttcacata gctggtcaag aagcgaatag ccaccatgct gaccgcaaaa
     5281 gctactccca tcgcgaccaa gagcaaaaac aattgcccaa agctcaagag ttctccggct
     5341 ttcacaaatt tgaaaatctt taaggcacta gctccaaaca taacgggaat cccaagatag
     5401 aaggtaaatt ctgtcacaac tgaacgattg gttccattta acaaaccacc gacaatcgtt
     5461 gcacctgaac ggctagtccc tggtaaaaga gcaagaactt ggaagagtcc gatatagaaa
     5521 gcggtcgtat aaggaagctt gtccaactct gttacacttg gctcgatagc acgcgcttta
     5581 ttgcgctttt ccaaatagat gaaggcaacc ccgtagataa tcaacatgag agcaactgaa
     5641 accatgttat ggaagtgggt atcaaaccaa tcatcaaatt taaagacacc aagtaaaggc
     5701 aaagtggcaa tcaagacctt caaccatagt ctccaagtct tacgaacttc ctgtttgtcc
     5761 ttagtcggtt taaaaggatt gagcttgtta aaataaatca ccataactgc taaaatagca
     5821 ccaagctgaa tcacgacatt aaacatggac ataaaggctt cattttgatt ttggtattgg
     5881 ataaactcct ctgctaaaat caagtgacct gtactggaaa tcggcaacca ttccgtaatt
     5941 ccttcaacaa tcccgaagaa gatagatttt aaaatttcaa taagatacat atatttctcc
     6001 ttatattata tttaacgcag ttagctactg ccaaagccca agtggtatac ttggaataag
     6061 ccactgtgga ttagttcatt tcctccaatc gcttgacgat ttccgaaagg gtctaaccac
     6121 agctttttgt ttcaattggt aatgagtttg ataacgcata gacgttttat ctcgtctaag
     6181 gtaacaaggc aaaaagttcg tggataacca agtagacttg aaatactata tctggaggta
     6241 ctcccatgct ttatgtgggc attgatgtcg ctaaaaataa acacgatgtt acagccttga
     6301 atgttccagg aaaaactgtt cttaaaccac tcactttttc aaataataaa gctggttttg
     6361 aactcttaga tctgtctttt cgacagctca accaagactg tctcatcgct cttgaagata
     6421 ctggacatta tgcctttaat ctactgaact tcctgcatga acaaggatat aaagtttaca
     6481 cctacactcc tttgctcatc aaggaatttg ccaaatcatt atcacttcgc aagactaaaa
     6541 cggataagaa agacgctcat ggcatcgctc ttaaacttct ttctgacccc aatcgtgaac
     6601 aatttcaaca cgataatcgg caaatagaac taaaaatact ggctagacat attcatcgtc
     6661 tcaagaaaaa acagtctgat tggaaagtac aatacactcg ttgtcttgat atcatctttc
     6721 ctgagttgga taaaatcgtt ggaaagcatt cagaatatac ctaccaactc ttgacacgct
     6781 accctaatcc tcagaaaagg cttgaggcag gatttgataa gctgatagaa attaagcgat
     6841 tgaccgcttc taaaattcag gatatcctct cagtcgcacc tcgttctatc ggaacaacat
     6901 ctcctgctcg tgaattcgaa atcatcgaaa tcatcaaaca ttacaagagg ctcattgaca
     6961 aggcggaaac atgtgtcaat gacttgatgg ctgagttcaa ctcggtcatc acgacggtta
     7021 ctgggattgg gggtcgttta ggggcggtca ttttagccga gattcgaaat attcatgcct
     7081 ttgataatcc tgctcaatta caagctttcg ctggactgga ttcttctatt tatcagtcag
     7141 atcagattga tttagcagga agaatggtca aacggagttc ccctcatctg cggtaggtac
     7201 tcatacaagc tgccaaagca tgccctcgct tttcacctgc ttttaaggcc tatcttaaga
     7261 ctaagttaga ataaggaaaa cattacaatg tagccatcat ccaccttgca aaaaaactta
     7321 tccgaaccct gttttatatc ctaaaaaaga gctgccattt gacgaacaaa aagtgatgta
     7381 atttctgaaa ttaacacagg attacctttg aaaaaatgga ctttttcaag ggctttttgc
     7441 cgtgctctaa aatcatcgcc aaatcatcaa attgaaataa gaaatagttt agataaaact
     7501 attgactttt cttatagttt gtctttcttc tatcttccat tatatcatac tttttcagtc
     7561 tatggtagct ctctttaaaa ggctccgata ctgccgccac ctccgcctcc agagaagcca
     7621 ccaccagaac ttccacttcc agaagataca gagtaggtac ttgctgtatt tgcgacacta
     7681 gcataatggc tcatttgcgc gcttgaatga taaaacatac tgtgccagcc ataagctaca
     7741 tagagattga tatctggatt ttcaacttga atctgatgaa ccttcatcaa atgactaacc
     7801 ttgtccgcat agccaaataa ggttgcatag accaagagac gattccaaac aacaatactt
     7861 tccaattcag ccttatccag tcgtgcaatc tcacgtaaca tattttcaaa actggtccag
     7921 agatagtaga cctcagctcc cgcttcattt agaacaccat cacgattatc tagtcgaagc
     7981 ttccaataat agaaaacaga caaaactaac cctagaaaac caagtattgg caaagggagg
     8041 taaagatagc catgaacgtc taaactgtac aagaacaaac caaatccgat aaataggggc
     8101 aagatagtca agacacccat acccacttgc aaagcctttt ccaaaccagt taaaggacga
     8161 tagtaatctg ggagtcccca gaagacaact cgctttctca ctccttcttg catctctttt
     8221 aatactgctt cgaaagaaga tttgagctga atccctcttg cttgaatccg tttctcatca
     8281 gcagctttag ctccgcgata aaggctgtca gataccttgt aatccgcaaa caaattggaa
     8341 agagtggctt cttttttgcc tgaaaaggct agatttagac agtctctctc aaatcttgac
     8401 aaaccatctt ctttcaccaa tctcaagcca actgcatctc cttctgaaat aatagaaaca
     8461 ttcccacggt ccatcacatc tagcaaggta gcttgaataa gttggtcaaa agtgaatttg
     8521 ccagccccct tgactaaggg actcacttcc tccaaggagg tcgagtagac agcctctgat
     8581 aaaaccatag gctctaattc cattggtggt tcatagagac gatgattttt ggcatatttg
     8641 actgaaggag tggtctttct tctataaata aaatagaagc agacactcaa taacaaggag
     8701 atagaaagga tcgaagggag gacccaagta acaagttgtt tactctgatc tttttctcta
     8761 acaatcgagt cttctatctt attaaactct tctaaacgat tccctttcaa tccctgatcc
     8821 ctagcgctag caaaatcggt ccgaggccag taggcatgca actcaactcc acgcttagcc
     8881 ggaagattgt ctaaacggat agtataatca aggttactct tttcaatcgt tccctctcta
     8941 aaaagtttcc ctgtatggaa aaagagtttt tcagccccct tgtctcccct tacatgaaat
     9001 tcaaactttt caatagactc tgaactatct gtcagaggtt gccaatttaa ttcagcgata
     9061 tcatcataaa ggaaaagtaa attttttaag ttccagacga ggtcaacttc aactatgtcg
     9121 ccctcctgac ctggattata gactctcaca gtataaccat ccgcttcttc tgttacttcg
     9181 ctagtcacat ctgctagttc tgcaccgttt ttcgcggcct gaacctttgg atgagggtca
     9241 atgtcaaacc cgctaggcat cttaccagca cgtccaagtc ccacgatttg tcccttaaag
     9301 tcctcctcaa actggtaaac tatcttctgt ctaaactctg ccgtattatc tgcatgaata
     9361 tacaaatccc cttgataaga gtttatcttg aaatcaatgg caaaaacaga gagtggaaga
     9421 aggcaaaaca agcctaacac cagtaagaaa aaagtttttt tcatcaacta agcccccttt
     9481 ttatctttct tatcattata gcattttttc gtaagtaaag gcttacttat gttgaaaaat
     9541 tacgcatttt tcgataaaat aggagacagt tattttttaa tagatcagaa taggagaaat
     9601 catgagaaaa atatacttat ctattttcac aagtctcttg ctgatgctag gacttgtcaa
     9661 tgttgctcaa gccgatgaat atttacgcat cgggatggaa gcagcatatg ctccctttaa
     9721 ctggacccag gatgatgata gcaacggagc tgtcaaaatc gatgggacca atcagtatgc
     9781 caacggatac gatgttcaaa tcgccaagaa aatcgctaag gacttaggta aagaaccttt
     9841 ggttgttaaa accaagtggg aaggtctagt ccctgccctt acttctggta agattgacat
     9901 gattatcgca ggtatgagtc caactgcaga acgcaaacaa gaaattgcct tttcgagcag
     9961 ttactacact agcgaaccag ttttgcttgt caaaaaagat tctgcctacg caagtgctaa
    10021 atctttggat gactttaacg gtgcaaaaat cacttctcaa caaggggtct acctctacga
    10081 cttgattgca caaatcccag gtgctaaaaa agaaacagcc atgggagact tcgctcaaat
    10141 gcgccaagct cttgaggctg gtgtcattga tgcttatgtt tctgaacgtc cagaagcact
    10201 gactgctgaa gctgcgaact ctaagttcaa gatgattcaa gtagaacctg gtttcaaaac
    10261 tggggaagaa gatacagcta tcgctatcgg gcttcgtaaa aatgacaatc gtattagcca
    10321 aatcaatgcc agcattgaaa ccatttcaaa agatgaccaa gttgccttga tggatcgtat
    10381 gatcaaggaa caacctgccg aagctacaac aactgaagag actagcagta gtttctttag
    10441 ccaagtcgct aaaattcttt ctgaaaactg gcaacaactc ttgcgtggtg ctggtatcac
    10501 tcttttaatc tctatcgtcg gaaccatcac aggtctcatt attggacttg ccattggtgt
    10561 tttccgtact gctcctctct ctgaaaacaa agtcatttac agcctgcaaa aactagtcgg
    10621 ctggatcctc aacgtctaca ttgaaatttt ccgtggtacg ccaatgattg ttcaatcgat
    10681 ggttatctac tatggaactg cccaagcttt cggtatcaac cttgaccgta cactggctgc
    10741 tatcttcatc gtttcaatca ataccggtgc ctacatgact gaaatcgtcc gtggtggtat
    10801 cctggcagtt gacaagggac aatttgaagc tgcgactgct cttggtatga ctcataacca
    10861 aaccatgtgt aagattgtcc tacctcaggt tgtccgcaat atcctaccag caactggtaa
    10921 tgaatttgtc atcaatatca aagatacatc tgtattgaac gttatctctg ttgtcgagct
    10981 ttatttctca ggaaataccg tggcaacaca aacctatcaa tacttccaga catttacaat
    11041 catcgccgtg atttactttg tcctcacctt caccgtaaca cgtatcctac gctttatcga
    11101 gcgcagaatg gacatggata cctacactac aggtgctaac caaatgcaaa cggaggattt
    11161 gaaataatga cacaagcaat ccttgaaatt aaacacctca aaaaatccta tggacaaaac
    11221 gaagtgctaa aagacatttc actcactgtc cacaagggag aggtcatctc tatcatcgga
    11281 agctctggaa gcggaaaatc gaccttccta cgctccatta acctacttga aacaccaact
    11341 gatggacaaa tcctttatca tggacaaaac gtcctcgaaa aaggctatga cctcacgcaa
    11401 taccgtgaaa agttggggat ggttttccaa tcctttaacc tctttgaaaa tctcaatgtt
    11461 cttgaaaaca caatcgtcgc tcagacaact gtcctaaaac gcgaacgcac agaagctgaa
    11521 aagattgcca aagaaaacct ggaaaaggtc ggcatgggag aacgctactg gcaagccaaa
    11581 ccaaaacaac tctcaggtgg tcaaaaacaa cgtgtggcca tcgctcgtgc cctctccatg
    11641 aatccggacg ctattctctt tgatgaacca acatcagctc tcgatccaga aatggttgga
    11701 gaagtcctca aaatcatgca ggacctggct caggaaggct tgaccatgat tgtcgtaacc
    11761 catgaaatgg aatttgcccg tgatgtctct caccgtgtta tctttatgga taagggcgtg
    11821 atcgctgaag aaggtaaacc agaagacctc ttcaccaatc ctaaagaaga ccgaacaaaa
    11881 gagttccttc aacgctatct caaataaaaa gaaaaggctg catcaaccgt gcagtctttt
    11941 tgctgtcctc aaaatgaaaa ggcagattct ctatctctac tacttgaagg tcaagaatcc
    12001 gccgttatcc aaagattaat cttcaaattt ttcataattt ttttcataga aatcaattag
    12061 gcctagggct gtttcaaatg aaatattttt tacttttgca cgaccctgcg ccagagcaat
    12121 gatagacatt tcacgcgcat tcgtttcttt agagatacgg tagcctgtga ttttcttatc
    12181 acgaacccag ccaacaactg attctacttt ttcaaagttt gacttagcca tgtttttctc
    12241 ctattttctt ctttataata tttaattgta tacgttttta ctacttttgt caa
//
LOCUS       DAVLDI010000066        11910 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLDI010000066 DAVLDI010000000
VERSION     DAVLDI010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11910
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.066"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            144..797
                     /locus_tag="VXD01_001928"
     CDS             144..797
                     /locus_tag="VXD01_001928"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV0602270.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            807..1271
                     /locus_tag="VXD01_001929"
     CDS             807..1271
                     /locus_tag="VXD01_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV0602271.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1284..2552
                     /locus_tag="VXD01_001930"
     CDS             1284..2552
                     /locus_tag="VXD01_001930"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV0602272.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKVPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2566..2826
                     /locus_tag="VXD01_001931"
     CDS             2566..2826
                     /locus_tag="VXD01_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602273.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2837..4198
                     /gene="pdrM"
                     /locus_tag="VXD01_001932"
     CDS             2837..4198
                     /gene="pdrM"
                     /locus_tag="VXD01_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV0602274.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4352..5320
                     /locus_tag="VXD01_001933"
     CDS             4352..5320
                     /locus_tag="VXD01_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV0602275.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5336..6328
                     /locus_tag="VXD01_001934"
     CDS             5336..6328
                     /locus_tag="VXD01_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV0602276.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFDPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKNAIRKTYNKE"
     gene            6546..7589
                     /locus_tag="VXD01_001935"
     CDS             6546..7589
                     /locus_tag="VXD01_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV0602277.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDIIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7653..9338
                     /gene="lpdA"
                     /locus_tag="VXD01_001936"
     CDS             7653..9338
                     /gene="lpdA"
                     /locus_tag="VXD01_001936"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV0602278.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EENGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVSGMESSLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVAAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9402..10391
                     /locus_tag="VXD01_001937"
     CDS             9402..10391
                     /locus_tag="VXD01_001937"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV0602279.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDALRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10464..11534)
                     /gene="xerS"
                     /locus_tag="VXD01_001938"
     CDS             complement(10464..11534)
                     /gene="xerS"
                     /locus_tag="VXD01_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV0602280.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
BASE COUNT         3539 a         2223 c         2661 g         3487 t
ORIGIN      
        1 aaaaatagcc agtctttata aactgtattc acgtattcaa atcgtatata gtcgatttat
       61 taaatcttta gataaattgt aaaaagtggt ttccatagcc actttttgct ataatagagg
      121 cagtaaaaat gaaggagtca gctatggaac actcgtcttg gcatgctttg attaaggcgc
      181 aattacctga gggttatttc gggaaaatca atcagtttat ggagcaggtc tattctcagg
      241 ggattattta tccacccaag gaaaaggttt ttcaggctct cttgacaaca ctgcttgaag
      301 aagttaaggt ggtaattcta gggcaagacc cctatcacgg accaggtcaa gcgcagggct
      361 tgagtttttc tgtacctgac tctatcccag ctccaccatc cttgcaaaat atcttgaaag
      421 aattgtcaga tgatatcgga gttaagaaat ctcatgattt gacagcttgg gctgagcaag
      481 gagtcttgct tcttaatgct tgtttgactg ttcctgctgg acaggccaat ggtcatgctg
      541 gtcaaatctg ggagcctttt actgatgctg tgattcaggt ggtcaatcat ctagatagac
      601 cagtcgtttt tgtactctgg ggagcttatg cacgtaagaa gaaggcctta gttaccaatc
      661 ctcatcactt gattatcgaa tcagcccatc caagtccttt gtcggtttat agaggatttt
      721 ggggttccaa gcccttttcc aaggccaatg cattcttaaa agagacagga caagagccaa
      781 tcgattggct tagataagga gaaaatatgc ctcagttagc gacgatttgc tacattgata
      841 atgggaaaga actgctcatg ctccatcgta ataagaaacc caatgatgtc catgaaggga
      901 aatggattgg tgtgggtggt aagctagaga gaggagagac gccccaggaa tgcgcggtgc
      961 gtgaaatcct tgaagaaaca gggctcaaag ccaagccagt tctaaaaggt gtcatcactt
     1021 ttcctgaatt tacaccagat ttagactggt acacctatgt ttttaaggtg acggagtttg
     1081 agggcgactt gattgactgc aatgagggga cgctagaatg ggttccctat gatgaggttt
     1141 tgagcaagcc gacttgggaa ggtgaccaca cctttgttga gtggctttta gaggataaac
     1201 ccttcttttc agccaagttt gtttatgatg gggataaatt gttggatacc caagttgatt
     1261 tctatgaata aaggagaaag cagatgctac taatcaaaaa tggtcgtgta atggatccta
     1321 agtctggttt ggatcaagtt tgtgatgtct tagttcaaga tgggaaaatt atcaaaattg
     1381 cgcctgagat cacggaagaa ggagcagaaa cgattgatgc tactggtctt gtggttgctc
     1441 ctggtttggt cgatattcat gtgcatttcc gtgaacctgg tcaaacacat aaagaagaca
     1501 ttcatactgg tgccctagca gccgctgcag gtggttttac tactgtcgtc atgatggcta
     1561 ataccagtcc aaccatttca gacgtggaga ctttgcaagc agtcctccag tcagctgcca
     1621 aagagaagat taatgtcaag acagttgcga ccattactaa aaactttaat ggtaaaaact
     1681 tgactgactt taaggcactt ttagaagctg gtgcggttgg tttctctgat gacggtattc
     1741 cgcttgagag cagtaagatt gtcaaggaag ccatggagga agccaaaaaa ctcaatacct
     1801 ttatcagcct tcatgaggaa gatccaggtt tgaacggtgt tcttggcttt aatgaaaata
     1861 ttgctagaga acatttccat atctgcggtg ctactggggt ggctgagtac gctatgatgg
     1921 cgcgtgatgt catgattgcc tatgcaacta aagcccatgt tcacatccag catttgtcta
     1981 aggaagaaag tgttaaagta gtggagtttg ctcaggggtt aggtgcagaa gtcacagcag
     2041 aagtagcgcc acagcatttc tctaagacag aagcacttct tttaacacaa ggtagcaatg
     2101 ctaagatgaa tccaccgctt cgtttggaat cagaccgtcg tgccgttatc gaaggtctca
     2161 aatcaggtgt catcacagtt attgcgactg accacgcgcc tcatcatgta gatgaaaaaa
     2221 atgttgagga tattaccaaa gtaccatctg gtatgactgg cttagaaaca tccctgtctc
     2281 tcggcttgac ctatttagta gaagctggtg agttgagctt gatggaatta cttgaaaaaa
     2341 tgacatacaa cccagccaag ctttacaact ttgaagcagg ttacttggct gagaatggtc
     2401 cagcagatat cactattttt gatgccaagg ctgaccgcct tgtggactcc cattttgctt
     2461 ccaaagcagc taattcacca ttcatcggtg aaaccttaaa agggcaggtt aaatatacca
     2521 tctgtaaggg acaaatcgtc tatcaagctt gataggagtt agaatatgaa ttattttcga
     2581 aaacgtaggg agagacaagc gaaatctaat agtggaattt actgtcccgc agctaatcgt
     2641 tccaaaattc aatatgaaac taaagaaaaa gctgaccatg cggttcaata tgataacgga
     2701 ggtttagtta gaagctatta ttgtcgtaca tgtgcgtgtt ggcatactac ttcaaaatct
     2761 aataaacctc cgctaagttt gaaaaactat ggtctgaaac tctttggttt agataaatca
     2821 gaatagaaag agaagtatgt ataagacaaa gtgtttacga gagaagttag tattattttt
     2881 aaaaattttc ttcccaatcc tgatctacca atttgccaat tattctgcct cttttgttga
     2941 tactgcaatg acaggtcaat acaacactat ggacttggct ggtgtatcta tggcaaccag
     3001 tatctggaat cctttcttta catttctaac agggattgtg tcagccttgg tgcctatcat
     3061 tggtcaccat cttggtcgag gcaaaaagga agaagttgcg tctgattttt accaatttat
     3121 ttatttggcc ttgggcctat ctgtggtctt gctggggatg gtacttttct tggcaccaac
     3181 aatcttgaat catattgggt tagaagcagc agtagcggca gtagcggttc gctatctttg
     3241 gtttttatct atcgggatta tccccttgtt gctctttagc gtcattcgtt ccttgctgga
     3301 ttcgctgggc ttgaccaaac tgtccatgta cctcatgctt ttgttactcc ctctcaatag
     3361 cggatttaac tatctcttga tttacggtgc ctttggtgtt ccagaactgg gaggggctgg
     3421 tgctggttta ggaacatcct tggcctactg ggtcttgctt gggatttctg ttctggtttt
     3481 atttaaacag gagaagctca aagccttaca ccttgagaaa cgaattccac ttaatatgga
     3541 taaaattaag gaaggagttc gtttaggtct gcctattggg ggaactgtct tcgcggaagt
     3601 ggctgtcttt tcagtggttg gcttgattat ggctaagttt tcgtccttga ttatagctag
     3661 tcaccagtca gctatgaact tttcaagtct tatgtacgcc tttcctatga gtatctcatc
     3721 ggctatggct attgtcgttt cctatgaagt gggagccaag cgatttgatg atgcgaaaac
     3781 ctatattggt ctaggaagat ggactgccct catttttgcg gccttcacct taaccttcct
     3841 ttacattttt aggggaaatg tggccagtct ttatggtaac gacccaaaat ttatcgattt
     3901 gacagcgcgt tttttaactt atagtctttt cttccagtta gcagatacct ttgcggcgcc
     3961 gcttcaggga attttgcggg ggtataagga tacagttatt cctttttacc ttggtttgct
     4021 tggttattgg ggcgtagcaa tccctgtggc tacgctattt gattccctaa cagattttgg
     4081 agcttattct tactggatcg gcttgattat tagtttgatt gtgagtgggg cgctctaccg
     4141 ttggcgttta actgtgatta tgaagagatt tgaatcttta gcaaaatcca aacgctaaaa
     4201 agtttgtgaa aaaatatcct tgacaagaaa atcccttgtt ttcacggggt tttctttttt
     4261 attttgtgaa atttctttta gaaaaacttt gacagtattt gccaaaagcg gtaaaatagt
     4321 aaggtaagaa gaaagttaga aaggcaagaa gatgtcaact ttagataaaa atcttttgct
     4381 agaaatgttc cgtaagatgg aagaaatccg tcgcatggac ttaaaaattg cacaattagt
     4441 aaagaaaggg aaagtgccag gaatgacgca cttttctgtt ggtgaagagg cagctaacgt
     4501 gggggctatg ttagctctca atccagatga tctgattacc tcaaaccacc gtggacacgg
     4561 gcaagctatt gctaaaggga ttgacctcaa cggaatgatg gctgaaatcc ttggtaaata
     4621 cactggaacc tgtaaaggga aaggtggatc tatgcatatc gctgaccttg atgctgggaa
     4681 ccttggtgcc aatggtatcg taggtggtgg tatggggatc gctgtcggtg cagccctcag
     4741 tcagcaaatg caaaataccg gtaaaatcgt tgtctgcttc tttggagatg gtgcgaccaa
     4801 tgaaggtgtt ttccacgaag cagtgaacat ggcttctatc tggaacctgc cagtcatttt
     4861 ctattgcatt aacaacggtt acggtatctc tgcggatatc aagaaaatga ccaatataga
     4921 acatatccat caacgtagcg ccgcttatgg aattcctgga atgttcatcg aagatggtaa
     4981 caatgtcatc gatgtctatg aaggatttca gaaagctgtg gaccatgttc gcagtggcaa
     5041 tggtccagtc ttgattgaaa gtgtaactta tcgctggctc ggtcactcat catctgaccc
     5101 tggtaaatat cgtacgcgtg aagaagtgga attgtggaaa caaaaagatc caatcgaaaa
     5161 cctccgcaat taccttattg aaaataacat tgcaagtgcc gaagaattgg aagaaatcca
     5221 agcgcaagta aaggaagcag tagaagcttc tgttaaattt gcagaggaaa gcccattccc
     5281 accgcttgaa tcagcctttg aagatattta cgcagactaa ggagaaagag ataaaatgga
     5341 aacaaaaaca atgtccttcc gtgacaccat tatccttgct atgtctgagg aaatgcgtcg
     5401 cgatgaaaat gtgttcttga tgggagaaga cgtcggtgtc ttcggaggag acttcggtac
     5461 ttctgttgga atgcttgaag aatttgatcc agaacgtgtc cgtgactgtc cgatttctga
     5521 agctgccatc tctggagcag cagcaggagc agccatgaca ggacttcgtc caatcgtcga
     5581 tatgaccttc atggacttct ctgttattgc catggacaat atcgtcaacc aagctgctaa
     5641 aacacgttac atgtttggtg gtaaaggtca ggttccaatg actgttcgtt gtgcagctgg
     5701 taacggagtt ggctctgccg cccagcactc acaatctcta gagtcttggt ttactcacat
     5761 tccaggactt aaggttgtgg cacctggaac acctgcggac atgaaaggcc tgcttaagtc
     5821 ttctatccgt gataacaacc cagttattat acttgagtac aagtcagaat ttaaccaaaa
     5881 aggggaagtg ccagttgatc cagactacac aattccactt ggggttggtg aaatcaaacg
     5941 ccaaggaacg gatgtaacag ttgttactta tggaaaaatg cttcgccgtg tggttcaagc
     6001 tgctgaagaa ttagcagaag aaggaatttc agttgaaatt gttgacccac gtacccttgt
     6061 tccgcttgat aaggatatca tcataaactc agtgaagaag actggtaagg ttgttctggt
     6121 caacgatgcc cacaaaacaa gtggctatat cggtgaaatt tcagctatta tttcagaatc
     6181 agaagcattt gactatctag atgcaccaat tcgccgttgt gcaggagaag atgtgccgat
     6241 gccttatgca caaaacctag aaaatgcaat gattccaaca gttgaaagta tcaaaaatgc
     6301 aatccgaaaa acttataaca aagaatagag ttacataaga taagttatgt aaataaaata
     6361 aagctgacga gaaactttgt atcttttagg tgcagagctc ttcgtcatta atatcttaga
     6421 ttagagcacg ggctaaaagc tcggaaaaaa gataaatctc cttggcttca tcgaagccat
     6481 cgtcgatttc ctatttttca gtcgcttttg acgccctttg tatcataaat agaattggag
     6541 aggtcatggc tgatgacaag ctaagagcga ctcctgcagc tagaaagtta gcggatgatt
     6601 tagggataaa cctctacgac gtttctggct caggtgcaaa cggtcgtgtc cacaaagaag
     6661 acgtggaaac ttataaagac acaaacgtgg ttcgcatttc gccacttgca aaacgaattg
     6721 ccctcgaaca taacattgct tggcaggaaa tccaaggaac cggtcatcgt ggtaaaatca
     6781 tgaagaagga tgttttggcc ctgcttcctg aaaatatcga aaacgatagc atcaaatctc
     6841 ctgctcagat tgaaaaagtg gaagaagtcc ctgataacgt aacaccatat ggtgaaatcg
     6901 agcgtattcc aatgacacca atgcgtaagg ttattgccca acgcatggtt gaatcttact
     6961 tgactgcgcc aaccttcacc ctcaactatg aagttgatat gactgaaatg ttggctcttc
     7021 gtaagaaggt tcttgagcca atcatggaag caactgggaa gaagactacg gtaacagacc
     7081 ttctttcgct tgcagttgtt aagactctta tgaaacaccc atacatcaat gcttcattga
     7141 cagaagatgg caagactatt atcactcaca actatgtcaa tcttgccatg gcagttggga
     7201 tggataatgg attgatgaca cctgttgttt acaatgctga gaagatgagt ctttcagaac
     7261 tggttgtagc ctttaaggat attattggcc gtaccttgga tggtaaattg gctccaagtg
     7321 agttacaaaa ttcaacattc acaatcagta atttgggaat gtttggtgtt cagtcctttg
     7381 gcccgattat taaccaaccc aactcagcta tccttggtgt cagttcgaca atcgagaagc
     7441 cagttgtcgt caatggtgaa attgtgattc gcccaatcat gagtttagga ttaaccattg
     7501 accaccgtgt cgtagatggt atggctggtg ctaagtttat gaaggacttg aaagagttga
     7561 ttgaaacgcc aatctcaatg ttaatttaag agcaagagta ttcattttta agatatagat
     7621 aaaggaagga agacatggcc ttagaagtaa ttatgccaaa agccggcgtg gatatgacag
     7681 aaggacaaat cgtccaatgg aataaaaaag tcggagaatt tgtaaaagaa ggagaaatcc
     7741 ttttggaaat catgactgat aaagtcagca tggaattgga agccgaagaa aatggatact
     7801 tgattgccat tctcaaagga gatggtgaaa ctgtccctgt aacggaagtt atcggttacc
     7861 ttggtgaaga aagggaaaac atcccaacag ctggagcagc atcgccagaa gctagccctg
     7921 tacctgtagc aagtacctca aacgatgatg gtaagagcga tgatgctttt gatatcgttg
     7981 tgattggtgg aggtcctgct ggttatgttg cagccattaa agctgcccaa ctcggcggta
     8041 aggttgccct tgttgagaaa tctgaacttg gtggaacctg cttaaaccgt ggatgtattc
     8101 caaccaagac ctaccttcat aacgctgaaa ttattgaaaa tatcggtcat gctgcaaatc
     8161 gtggtatcgt gattgaaaat cctaacttca ctgttgatat ggaaaaactt ttagaaacta
     8221 aatctaaagt tgttaatact cttgttggtg gtgttgcagg acttcttcgt agctacggag
     8281 ttactgttca taaaggaatt ggtacaatca ctaaagacaa gaacgtcttg gtaaatggtt
     8341 ctgaattgct tgaaaccaag aaaatcattc ttgctggtgg ttcaaaagtc agcaagatca
     8401 acgtctctgg tatggaatct tcacttgtca tgactagtga tgacattctt gaaatgaacg
     8461 aagtgccaga aagccttgtt atcatcggtg gtggagttgt cggtatcgaa ctcggtcagg
     8521 ccttcatgac atttggttca aaagtgactg ttatcgaaat gatggaccgt atagttccag
     8581 ctatggatgc ggaagtttct aagaaccttc gcttgatcct tgagcgtaaa ggaatgacca
     8641 tcttgactgg tactaaactg caagaaatca ttgaggaaaa tggtcaactt cgtatcaagg
     8701 ttgaaggaaa agacgatatc atcgcaagca aagctcttct ttcaattggt cgtatgccag
     8761 accttgaagg tattggagag gttgagtttg aattggatcg tggttgtatc aaggtcaacg
     8821 aatacatgga aacttcagtt ccaggcattt atgcaccagg tgacatcaac ggtactaaga
     8881 tgttggctca cgcagctttc cgcatgggtg aagttgccgc tgaaaatgcc cttaaaggaa
     8941 atcatgcagt tgccaaattg aatttgactc ctgcagccat ctacactctc cctgaagtag
     9001 cagcagtagg tttgacagaa gaacaagccc gtgagaaata cgatgttgcc atcggtaagt
     9061 ttaactttgc tgctaacggt cgtgctattg catctgacgc agctcaaggt ttcgtaaaag
     9121 ttatcgctga taagaaatac ggagaaatcc ttggtgtaca cattattggt cctgcagccg
     9181 cagaattaat aaacgaagca tcaagcatca tcgaaatgga aatcactgtt gaggaaatgc
     9241 tgaagaccat ccacgggcac ccaacttact ctgaagtgat gtacgaagcg tttgcagatg
     9301 ttctaggaat ggccatccat tcacctaaga aaaaataaaa cgaagataga ttagactgga
     9361 aggttatttc cagtttctat catataaagt aaagggatat catgaaatac attatcaatc
     9421 attcaaatga cactgctttt aatattgcct tggaagaata cgcctttaaa caccttttgg
     9481 atgaggatca aatcttccta ctttggatta acaagccatc tatcattgtt ggtcgtcacc
     9541 agaacactat cgaagaaatc aaccgtgatt atgttcgcga aaatggtatt gaggtagttc
     9601 gccgtattag tggtggtgga gctgtttacc acgatttaaa taacctcaac tacacgatca
     9661 tctccaaaga agatgaaaat aaggcatttg acttcaagag cttctcaact ccggttatca
     9721 ataccctggc tcaactcggg gttaaagctg agttcacagg tcgtaatgac cttgagattg
     9781 atggtaagaa gttctgtggc aatgcccaag cctatatcaa cggccgtatc atgcaccacg
     9841 gttgcttgct ctttgacgtt gatttgtcag tcctcgcaaa tgcccttaag gtttcaaaag
     9901 ataaatttga atcaaaaggt gtgaaatccg tccgtgcccg tgtaactaat attatcaatg
     9961 aattaccaaa aaaaatcaca gtcgaaaaat tccgtgattt actcttggaa tacatgaaaa
    10021 aagagtaccc agagatgact gaatacgtct tttcagaaga agaattggcc gaaatcaatc
    10081 acatcaagga tactaagttt ggaacttggg actggaacta tggtaaatca cctgaattta
    10141 acgtccgtcg tggaaccaaa ttcactagtg gtaaggttga agtctttgct aacgttactg
    10201 aatcaaaaat ccaagacatc aagatttatg gtgacttctt tggtattgaa gacgttgctg
    10261 cagtagaaga tgcccttcgt ggggtgaaat acgaacgcga agatgttctt aaggcgctaa
    10321 aaaccattga tatcacacgc tacttcgctg gtattagccg tgaagaaatc gctgaagcgg
    10381 tagttggata aatcaaaaag aagttggcca actaaccaac ttcttttttt gatatttatt
    10441 tacataattt aaaatacgta aaattataaa ctatctagag cattcttttg ttcatcatta
    10501 acaatatggg tatagaggtc agtgacttgt gtgctagcat gtcctagttg gtgactgact
    10561 aaaacttgtg atttagttgc atcatagagc ctagttgcta gtgtatggcg cagtttatgg
    10621 ggtgttacac gcactttaaa atcctctgag tatttagcaa ccattttctc aacgctagaa
    10681 gcatcgatac gattaggaac acctctgtag agagttaaaa aaagggctgt atctgttttt
    10741 tccgttttat agcgttgatt ccgaatggcc agataattct ctaaataagg tttagcaaaa
    10801 gcagcgacat tgactgagtc acgtttgcca ccttttcgag taacatcaat aaccatcatt
    10861 tttagattga gatctcttag atctagatta acagcttcag ataagcgaac accagatgcc
    10921 aagagaaggg caataatggc taaatctcgt tctttatttt tgttgaatga tgagagagct
    10981 cgatttgaaa gctgttgtgg gtgctcttga tcgatataag ttagaaaacc ttctgtttca
    11041 tcacctagaa agagtttttg cttgatattt tcagctctgg cagcaagggt ttctttcttt
    11101 ttcttggttg aaactttttt cattacatta cgatagaaat aaggttcccc ctgatcgttt
    11161 tcaacctcct cggttagata tttgtaaaga ctagaaagtg ctgataaggt tcgattgata
    11221 gttgtctgtg aaacaccttg ttttgttgta ttagcattca gcaagggacg ttcacgtaga
    11281 taaaggataa aggattccat gtctttctta gacatatttt ccaaaactga taaaggaata
    11341 tcggatattt tatcagcgtt tgaaatacca gactccaaaa cccagctgaa aaatcggtca
    11401 tattccttaa ggtattcgta cagggttgta aaactgtagg gcacagccag cttagattgg
    11461 tagtattcca gaacatacca gggcatgagt tgttttagtt tgtcgattcg ttccagtaaa
    11521 atctcacgtt tcatgtattt tctccataag taagtatact agtagtatag catagacttg
    11581 tatatttttc aagaaaatta tagtttttct gaaagatgtt ataggagttt ttcaaagtga
    11641 taaaaagact tagacctaca aacaaaacag aataaggaaa ataataaaaa tctcacccac
    11701 taaacttctg ttaatactac ataactgaag agctatataa ggagctatga gatacaaaac
    11761 acattgtata gtataataga ttgaaactag aatagtacat ctgaacttct aaaacattgc
    11821 tagaaattga tttgattgtc ctgattgttt tatcctattt ctatttcatt tcactatata
    11881 attgctattg ttttcttttt catgatttta
//
LOCUS       DAVLDI010000067        11009 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLDI010000067 DAVLDI010000000
VERSION     DAVLDI010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11009
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.067"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            74..259
                     /gene="briC"
                     /locus_tag="VXD01_001939"
     CDS             74..259
                     /gene="briC"
                     /locus_tag="VXD01_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV0602281.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            277..750
                     /locus_tag="VXD01_001940"
     CDS             277..750
                     /locus_tag="VXD01_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602282.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            763..999
                     /locus_tag="VXD01_001941"
     CDS             763..999
                     /locus_tag="VXD01_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0602283.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(1048..1470)
                     /gene="nusB"
                     /locus_tag="VXD01_001942"
     CDS             complement(1048..1470)
                     /gene="nusB"
                     /locus_tag="VXD01_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV0602284.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(1463..1852)
                     /locus_tag="VXD01_001943"
     CDS             complement(1463..1852)
                     /locus_tag="VXD01_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0602285.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            complement(1874..2434)
                     /gene="efp"
                     /locus_tag="VXD01_001944"
     CDS             complement(1874..2434)
                     /gene="efp"
                     /locus_tag="VXD01_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV0602286.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            complement(2563..4005)
                     /gene="gatB"
                     /locus_tag="VXD01_001945"
     CDS             complement(2563..4005)
                     /gene="gatB"
                     /locus_tag="VXD01_001945"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV0602287.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            complement(4005..5471)
                     /gene="gatA"
                     /locus_tag="VXD01_001946"
     CDS             complement(4005..5471)
                     /gene="gatA"
                     /locus_tag="VXD01_001946"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV0602288.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLNSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            complement(5471..5773)
                     /gene="gatC"
                     /locus_tag="VXD01_001947"
     CDS             complement(5471..5773)
                     /gene="gatC"
                     /locus_tag="VXD01_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV0602289.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVVEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            5986..7530
                     /locus_tag="VXD01_001948"
     CDS             5986..7530
                     /locus_tag="VXD01_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV0602290.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKEDERFASLEDGDKLFGSNPFYDQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            7958..8156
                     /locus_tag="VXD01_001949"
                     /pseudo
     CDS             7958..8156
                     /locus_tag="VXD01_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
     gene            8267..8443
                     /locus_tag="VXD01_001950"
     CDS             8267..8443
                     /locus_tag="VXD01_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV0602291.1"
                     /translation="MDLDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     NGMWRAENVTQDLI"
     gene            8559..8747
                     /locus_tag="VXD01_001951"
     CDS             8559..8747
                     /locus_tag="VXD01_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV0602292.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            8904..9269
                     /locus_tag="VXD01_001952"
     CDS             8904..9269
                     /locus_tag="VXD01_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0602293.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            9272..10939
                     /locus_tag="VXD01_001953"
     CDS             9272..10939
                     /locus_tag="VXD01_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV0602294.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
BASE COUNT         3167 a         2098 c         2485 g         3259 t
ORIGIN      
        1 aattaatttg actttcctga tagagttgtt cacatcttat ttcaaatcac tatattttaa
       61 gaaggtactt gcaatgacag gtacaaatac atttacagtt ctttcaactg aggacttgga
      121 gcaaacttca ggtggtcttg ctgtttggga agatggatat agtagatggt tatattatag
      181 agaatttgct ccctatatga ggcaaggggc acttaattct tatatagatg cttggaagta
      241 cggcttccga gcagggtaat ctttcaaaaa agtacgatga gaaacacaaa aaaactaaga
      301 caatttggaa tatttttgct tattatttta ctatctacct atttaccaca aacaattgga
      361 ttgtatgtga cgatcatttt agggttagga gctgatgtct attctcttat tttaacaatg
      421 ggattagtgg gaagtttcct tctattaatt tggaggttaa aaaagaaaaa gatgctcttt
      481 atctttgaga aaaagagctg gaactggtca tttgtcttct acttatttgc aacttatgtg
      541 gtttatcaga ttctcggtaa tttttgggca cgctatgctc atttgattaa tcataggaat
      601 attcatgatg agtattttac cgtgcttttt tcaaatggac aaccaacctt tttatcgact
      661 atcttatctt ttgtcctgcc tgtaatcatc ggtcctgttt ttgaggagac tcttgataga
      721 gggtatttta tgaatacctt ctttccctag tccaagtact atttggatgt tatcctatct
      781 gctatcatct ttgggattag ccatttgata ctatctcaca gagatccaat tagtttatta
      841 tattatagtc tgattggttt cttttttgcc cttgtttatc gttctaccga caatctgaga
      901 ttaacgattc tctgccatag tttttttaac tttctcaatc atgcaaaacc tatctggatt
      961 tttgtttaca attatatcta ttatcatttt tttagatagt gggaggcaaa gaaaaagtgt
     1021 ttgatatcta tcaaacactt tttcttttta ttgttcttct gttacaaact ggctgagcag
     1081 tccattgata aaacgggcag atttttgatc ggagaagtcc tttgcaagct cgatagcttc
     1141 attaacagca accagctgag gagtgtcaaa tgaagtgatt tcaaagactc ccaagcgaag
     1201 gaggtttctc tccacgagcg ttaagcgttc aatggtccaa cctgctttta aatgctgagt
     1261 gatttgctta tctagttctt cctttttagc ttgaacacca gaaacgaggt ctatcaaaaa
     1321 ggctggaagt tgtacatccg tatcttcacg atcatgagta taggcgaaac gacaagcagt
     1381 ttcgacatcc gtaccgaact caaggctcat gagagcttga aaagcgcatt tacggagttg
     1441 gcgtctagat tctaatagtg gactagtcat tgaggaagtc ctcgtcaaat agatctttca
     1501 attctggttt tggtgtttta tctgggacga tacctgcaac gtgaatattg atagcagcga
     1561 gttctacatc agccatatta cggacggcat ctttgacagc tttctggata gcaaccgcta
     1621 ccttaggaac ttttactccg tactcaaggt agagatagat atctgctgtg agttcttcgt
     1681 ccacgttttt aagataaatg ccacggccga gtgaaagttt tgaaagggta tcagacactg
     1741 atctgtttga aaaagagtga acaccctcta cctttgcagt agcgatagca atgatttttt
     1801 caagtacacg tggggcgata acgatttcgc caagttgttc ttcaattccc atagaatgac
     1861 ctctttctag agattaggca cgagaaacgt aagttccttc tgcagtgttg ataacgagtt
     1921 tttgtcctgc ttcgatgaag tctggaacgt ttacgacaag tccagtttcc atcgttgctg
     1981 gtttaccaga acctgtaaca gtagcacctt tgatagatgg ttgagtttca gcaactgtca
     2041 actcaacagt agtaggaacg gtgacaccga tcacttcagt tccgtagaat tggattttca
     2101 catcagagtt ttcaaggatg taaagcaatt cgttttcaac attgactaca gggatttcgt
     2161 attggtcgta agtttctgta ttcatgaagt atgctgtgtc atccattttg tacaagtatt
     2221 gagctgggac agtctcgata atagcttgtt caaatttttc ctctggacgg tagcttgtgt
     2281 caaatgtaga accagtacgg acatcacgca atttcatacg catgatcgtg tttcctttac
     2341 ctggtttgtg gtgactagct tccaaaacgc gaatcaattt gccgtcagct gtttcaaagg
     2401 tcataccagc ttttaattta cttgcttcaa tcatgttttt acctctttaa taaatattat
     2461 tactcttcat tttaccataa aatactctgg aaataaagcc aaaatagtta ttgggagttg
     2521 gtagagaaga aaaaaccaac cttagggctg gttttgttct gtctagtttt ctttcaactt
     2581 cgccaattcc tgtgcaagta gtttaagggc aacttgtggg ttggcttggc ctttggttgc
     2641 cttcataagg aatcctgtaa aggccttgtc ggcgttacgt ttgcctgact tgaagtcggc
     2701 aacagcagct tcgttatcgg caaagacttg gtggatgatt gggatcaaga tagctggatc
     2761 tgaaatttga accatacctg ctttttccac gtattcacgc gcgccaccgc catttttagc
     2821 tagatggaca aagactttct tggcaatctt agatgaaata gtaccgtctt cgatgatggt
     2881 aatcatttca accaagtttt ctggtgtcaa ttcgatttgt tccagtgttt taccttcagc
     2941 attcaagaac tgagcgactt ccccttggag ccagttagag acttgtttgg catcaccacc
     3001 tagggcaaca gctttttcaa agaagtcaga agtgacttta ttagcagtca actgactagc
     3061 atcgtagtct gataaaccaa ggtcagatac ataacgcgca cgacgttctt ttggaaactc
     3121 tggcaactca gtccgcattt cctcaatcca ctcgtcagaa atttcaaaga ggggtaggtc
     3181 tggttctggg aagtagcggt agtcagcagc cccttccttg acacgcatga ggatggttgc
     3241 tttattcgct tcatcgtaac ggcgtgtttc ttggcggatt tgaccacctg agcgaagaat
     3301 ttcagcctgg cgttggactt cgtattcaag ccccttgcga acgtttgaga aggagttgag
     3361 gttcttcaat tcagtcttgg taccgaattt ctcttgacca taaggacgaa gggagatgtt
     3421 ggcatccaca cgcatcgaac cttcctccat cttaacgtca gaaatgccag catactggat
     3481 aacttccttg agtgctgtca gataagcata ggcctcctct ggcgaacgca tatcggcttc
     3541 agatacaatc tcaatcaaag gtaccccttg gcggttaagg tcaacgtaag agtagccgtc
     3601 tgtaccgtgg gtgtttttac cagcgtcttc ctctaagtgg gcgcgttcga taccaatttt
     3661 cttggtcgta ccgtcttcta gctcgacttc aatccagccg ttataaccga ttggctcatc
     3721 aaactgagaa atttggtagg ctttgggatt atcagggtag aagtagttct tgcggtcaaa
     3781 gtgcattttt ttgtggatgt ccatgttgag ggcaagagca gccttgatac cggcatcaac
     3841 aaccccttta ttgagaactg gcagaactcc tgggaaagac cagtcaatca cgttagtgtt
     3901 ggcattttga tcatttccga agtgggcaga agtaggtgag aagatttttg aattggtgtt
     3961 gagctctacg tggacttcaa gtccgatgac tgtttcaaag ttcattagtt gtcacctcca
     4021 aaaatcacgg gttgttgttt gtggtagtct gttgttgctt caaaagcagc agcagcttgg
     4081 taaatggttt cctcagagta cttgggacca atcaattgga gtccgacagg tagaccttga
     4141 gagaatccag caggaatcga aattccaggc agtcctgcca agtttacagg tatggtcaat
     4201 aggtcggcta agtacatggc aactgggtca tggttgagag aattcaagtc ataggcaaca
     4261 cttggagcag ttggacccaa aatcaaatca taatccgcga agactttttc gaaatcttga
     4321 atgataagtg tacggacctg tccagccttc ttgtagtagg catcgtagta acctgatgaa
     4381 agactgaaag tacccagcat gatacggcgc ttcacttctt caccaaaacc ttggctacgg
     4441 ctgtttacat agatttcatc aagattagtc gcatcttctg cgcggtagcc gtaacggata
     4501 ccgtcaaaac gttgcaagtt tgatgaagct tctgatgaag cgatgatgta ataaacggca
     4561 acaccgtatt tagagtgagg aaggctgact tcttcgacga tagcacccaa tttttcaaag
     4621 tgtttggccg cgtttaagat tgtttcctta acctctggat caattccttc gcctaggtat
     4681 tccttaggca aagcaatttt catgcccttg atgtcttggc cgatttttga agtaaagtcg
     4741 gcgatgcgga caggagcaga agtagagtct ttagcatctt cgctggcaat agcgttgagt
     4801 aagagggcat tttccttaac agtaggagca aaaggtccaa tctggtctaa tgagctacca
     4861 aaggcaatga gaccgaaacg tgaaactgtt ccgtaggttg gtttgagacc aacgattccg
     4921 ttgaaggcag caggttggcg gatggaacca ccagtatcag aaccaagtga caagcgaact
     4981 tgtcctgagg ctacagctgc ggcagaacca cttgatgacc caccaggaac cttgctgtgg
     5041 tcccaagcgt ttttagttgc tccgtagtgt gaagtttcac ctgaaccacc catagcaaat
     5101 tcgtccatgt tggtctttcc aacgacaatc atgcccttgg tttttgcatt ggcaacagct
     5161 gtcgcatcaa agattggctc atagttgtag agcatttttg aggcagcagt tgtgagaata
     5221 ccgtctgtag agatgttatc cttaacagca agtggaattc ctgaaaggac attgtcagca
     5281 tcaattccag cttcatcaat ggctttagct tgaacaagag cttgctcctc agcgatggtg
     5341 acaaatgaat tgagggcttc ctcacgagac ttgatatttt caagtgttgc ttgggtcaat
     5401 tctgttgcag aaatttcctt agagacaagg agattgtgca actcttcaat agttttattg
     5461 ttaaaagtca ttaggcatct cctccatcgt ctaggatagc tggcaccttg atatagtagt
     5521 tgtcttgttc aggtacgttt ttaaacaagc gatcacggtc tgttccttct tcgaccacat
     5581 cagggcggag tacagtcttg cggtcagcca tagtcgtagt aggtgcgaca ccagttgtgt
     5641 caacttcgcc cagcaattca accatgtcaa caatcttaga caaggtggtc gcaaaggcag
     5701 cagtttcttc ttcagagaat cttaattttg aaagattggc aacgtgtgtt acctcttctt
     5761 gcgtaatttt catcttgcat cctttcgtga aatgatgatt tttagtctgt tctattttac
     5821 catattttcc tataaataag ggagggggaa gtgaaaagaa atagaaattg aaaaaaatgc
     5881 taaaatccga tataatggag tgttgaaagg aatggtaaaa tccaatgtaa aaatcattct
     5941 cagctattga aacaagaaaa atagagaatc aaagaaagag aacttatgaa tattcaagaa
     6001 gaaattaaga aacgtcgtac ctttgccatt atctcccacc cggacgcggg gaaaacaacc
     6061 atcactgagc agttactcta ctttgggggt gagattcgtg aggctggtac ggtaaaaggg
     6121 aagaaaacag ggacttttgc taaatctgac tggatggata tcgagaagca acgtgggatt
     6181 tctgttactt catctgttat gcaatttgac tacgacggca agcgcgtgaa tatcttagac
     6241 acgccagggc acgaggactt ctcagaagat acctatcgta ccttgatggc ggtggatgct
     6301 gcggtcatgg tcgtggactc tgccaagggg atcgaggctc aaaccaagaa attgtttgag
     6361 gttgtgaaac atcgtggcat tccagtcttt acctttatga acaagttgga tcgtgacggt
     6421 cgtgagcctt tggatctctt gcaagaattg gaagaaatct tgggcattgc tagctaccct
     6481 atgaactggc ctattgggat ggggaaagcc tttgagggct tgtatgacct ctataaccaa
     6541 cgtttagagc tttacaaaga ggatgagcgt tttgccagtc tagaagacgg ggacaaactc
     6601 tttggtagca atcctttcta cgatcaagtc aaggatgaca ttgagctttt aaatgaagct
     6661 gggaatgagt tttcagagga agctattctg gctggagaat tgacgcctgt ctttttcggt
     6721 tcagccctga caaactttgg tgtgcagacc ttccttgaaa ccttcctcaa gtttgctcca
     6781 gaaccacatg gtcacaagaa aacagacggt gaaattgtgg atccttatga caaggatttc
     6841 tcaggctttg tctttaaaat ccaagccaac atggaccctc gtcaccgtga ccgtattgcc
     6901 tttgtccgta tcgtatctgg cgaatttgag cgcggcatga gtgttaatct ccctcgtact
     6961 ggtaaggggg ctaaactgtc taatgttact cagtttatgg cggaaagtcg tgagaatgtg
     7021 accaatgccg tggcaggtga tattatcggg gtttacgata caggtactta tcaagttggg
     7081 gataccttga cagttggtaa aaacaagttt gaatttgaac cactgccaac ttttactcct
     7141 gaaattttca tgaaagtttc tgctaagaat gttatgaagc aaaaatcctt ccacaagggg
     7201 attgagcaat tggtgcaaga aggtgctatt cagctttata aaaattacca aacaggcgag
     7261 tacatgctgg gagctgttgg tcaactccag tttgaagtct ttaaacaccg tatggaaggc
     7321 gaatacaatg cggaagtggt catgagccca atgggtaaaa agaccgttcg ttggatcaag
     7381 cctgaggact tggatgaacg gatgtcgtca agtcgcaata tcttagccaa agaccgtttt
     7441 gaccaaccag tctttctctt tgaaaatgac tttgccctcc gctggtttgc ggacaagtat
     7501 ccagacgtag agttagagga gaagatgtga ctcagtatca acaattggaa ctaaagttcc
     7561 aaattgttgg acgctagtcg ctatttggcg aactagctaa ctgcctcact aactacgttt
     7621 ggcaaataga atcgatttgc caaactccgt gtcgtaatct aataatcggt aaccgctatg
     7681 gcggcttacc taaacgcttc actaggaaaa atccacgaat ggtattgatt tgtggatttt
     7741 tccgtcgtag cagaaagtag gtagcctagc taactgcctt actaactacg tttggcaaat
     7801 gaaatcgatt tgtaaaactc cgtgtcgtaa tgtaaaaatt gtaaaccgta atgggacttc
     7861 atctaaaatc tccactggta tggttttacg aacgaatggg cgaaaataat ggttacgtag
     7921 aaacatatga tgggaataaa aagaaatgag ataaagagtg aaagaagaga aaaaagcgat
     7981 tgtcttaggt gcagataatg cttatatgga taaagttgaa acaacaataa aatctctttg
     8041 tgttcatcta ttataatctt aagttttatg tttttaatga tgaccttccg cgagaatggt
     8101 tccaattgat ggaaaaaaga ctagagactt tgaatagtga gattgtgaat gtttagattg
     8161 acagtagtat tctgaaaggt tatcgtctcc cctttgaggg actttcatat gcggcttttt
     8221 tagatatttt attccaaagt atgtaagcga gtctcgtgta ctgtatttgg atttagatat
     8281 tgttgtaaga aaatcgatag acgagctgtg ggatttggac ttgacggcta tacccttagc
     8341 tgcagttaga gatgattttt atacacataa ttttaattct ggtgttctgt taatcaacaa
     8401 tggcatgtgg agagcagaaa atgtcacgca agacctgatt taagacacaa ataaaaaatc
     8461 ttccaattcc cttgcaaaaa acaagaaagt gtgataacat agtacggtat gtggtgctag
     8521 cacatccgct atattagatc taataggagg aaaacacaat ggctaaagta tgttacttta
     8581 caggtcgtaa gactgtatca ggaaacaacc gttcacacgc gatgaaccaa acaaaacgtg
     8641 ccgtaaaacc aaaccttcaa aaagttactg ttcttatcga tggtaaacct aaaaaagttt
     8701 gggcttcagc tcgtgctttg aaatcaggta aagttgaacg cgtttaataa taaaagcaaa
     8761 ggagacctta gggtcttttt tcttttattg tgggtataac atcgtttgaa aaatagagta
     8821 aatatccgct gatacatcat tctgctttta cacttgggct gaaatatgat aaaatagagt
     8881 atcaactagt tgaggtaaaa aggatgactg taaaaattaa tacaaaagat ggtcaaatcg
     8941 aactaacaga tgaagtgatt gcaaccgtcg taggtggagc agcaactgag atttttggtg
     9001 tggtcggtat ggctagtaaa aatgccctca aagataattt ccaagccctg ctaggtaagg
     9061 aaaattattc taaaggtgtc gtcgtaaagg cagccgaaga tggcagtatt gcagttgatg
     9121 tatataccgt gttaagctac ggaacaaaga ttagtgaagt gtcaaaaaac attcaagagc
     9181 gtgttgcctt tagcttggaa aaccagcttg gaattactgc tcagactgta aatgtctaca
     9241 ttcaaaatat caaagttgta ggagaataac cgtgtcaaaa attactacta gcttatttca
     9301 agaaatggtg caggctgcat caactcgctt gaataagcaa gctgaatatg tcaattcatt
     9361 aaacgtcttt ccagttccag atggagatac tgggacaaat atgggaatga ccattgaaaa
     9421 tggtgctaaa gaagttgcag acaagccagc ttctacagtt ggagaagtag cgagcattct
     9481 tgccaaaggg cttttgatgg gtgcgcgtgg gaactcagga gtgattacgt ctcagctttt
     9541 ccgtggattt tcccaagcta tcaaggataa agacgagtta acaggtcaag acttggctct
     9601 ggccttccaa tcaggtgtgg aagttgccta taaggcagtg atgaaacctg ttgaaggaac
     9661 gattttgaca gtttctcgtg gagctgctat cggtgctaag aaaaaagctg agcaaacaga
     9721 tgacactgtt gaagtcatgc gcgcagcctt ggaaggtgct aaaacagctc tagctaaaac
     9781 accagacatg cttccagtat tgaaagaagt tggcgttgtg gactcaggtg gtcaaggatt
     9841 ggtcttcatc tacgaaggtt tcctttcagc ccttactggc gaatatattg catctgagga
     9901 ctttgtagcg actcctgcca acatgagtga gatgatcaat gtagagcatc ataagtctgt
     9961 agctggtcac gtagcgactg aggacatcac gtttggttac tgtactgaaa tcatggtagc
    10021 tcttaagcaa ggtccaacct atgctaaaga ttttgactac gatgaattcc gtaactactt
    10081 ggatgagctt ggggattctc tcctcgttgt taacgatgat gaaattgtca aagtccatgt
    10141 tcatacagaa gatccaggac ttgttatgca agaaggtctc aaatatggta gcttggtcaa
    10201 ggtaaaagtt gacaatatgc gtaaccaaca cgaagcacag gttgagaaag aagctactca
    10261 agttatcaag tcggctgaag aaaaagagta tgctttaatt gctgtggtgg ctggtaaagg
    10321 tctagcagat atcttctgtt ctcaaggcgt ggactatgtt atcgaaggcg gtcaaaccat
    10381 gaacccttca acagaagact ttatcaaggc tgttgaacag gtcaatgccc gtaacatcat
    10441 cttcttgcca aacaacaaga acatcttcat ggcagctcaa tctgcggcag aagttttgga
    10501 gcaaccagca gtagtggtag aggctcgcac tcttcctcaa ggtatgacaa gtcttcttgc
    10561 ctttgatcca agcaagtcca ttgaagaaaa ccaagagcgt atgacagctg ctcttagcga
    10621 tgtcgttagc ggaagcgtca caacagccgt gcgtgataca acgatcgatg gcttagaaat
    10681 ccatgaaaac gataatctag gtatggtgga tggaaaaatt cttgtgtcaa accctgatat
    10741 gcaccaaaca ttgactgaaa ccttgaaaca tatgttggat gaagacagtg aaatcgtaac
    10801 cttctatgtc ggtgaagacg gaagcgaaga acttgccaat gaaatcgctc aagaaatcgt
    10861 agaagaattc gaagacgttg aagtcgagat tcaccaaggt caacaacctg tttacccata
    10921 cctatttagt gtggaataag attaatgaag gactgagaaa tcagttcttt tttctttttt
    10981 agtaaatgaa atcggtatct ttttaataa
//
LOCUS       DAVLDI010000068        10790 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLDI010000068 DAVLDI010000000
VERSION     DAVLDI010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10790
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.068"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            145..309
                     /locus_tag="VXD01_001954"
     CDS             145..309
                     /locus_tag="VXD01_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV0602295.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            393..959
                     /gene="amaP"
                     /locus_tag="VXD01_001955"
     CDS             393..959
                     /gene="amaP"
                     /locus_tag="VXD01_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV0602296.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            971..1141
                     /locus_tag="VXD01_001956"
     CDS             971..1141
                     /locus_tag="VXD01_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV0602297.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1180..1788
                     /locus_tag="VXD01_001957"
     CDS             1180..1788
                     /locus_tag="VXD01_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV0602298.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1819..2022
                     /locus_tag="VXD01_001958"
     CDS             1819..2022
                     /locus_tag="VXD01_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV0602299.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2132..2410)
                     /locus_tag="VXD01_001959"
                     /pseudo
     CDS             complement(2132..2410)
                     /locus_tag="VXD01_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2608..2895
                     /locus_tag="VXD01_001960"
     CDS             2608..2895
                     /locus_tag="VXD01_001960"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV0602300.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3173..3943)
                     /locus_tag="VXD01_001961"
     CDS             complement(3173..3943)
                     /locus_tag="VXD01_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV0602301.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3958..4806)
                     /locus_tag="VXD01_001962"
     CDS             complement(3958..4806)
                     /locus_tag="VXD01_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEV0602302.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYSHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4803..6278)
                     /locus_tag="VXD01_001963"
     CDS             complement(4803..6278)
                     /locus_tag="VXD01_001963"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV0602303.1"
                     /translation="MVQTKQPNIILIVVDQMRADVLSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6601..7956)
                     /locus_tag="VXD01_001964"
     CDS             complement(6601..7956)
                     /locus_tag="VXD01_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0602304.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMVDKTEL
                     S"
     gene            complement(7966..8283)
                     /locus_tag="VXD01_001965"
     CDS             complement(7966..8283)
                     /locus_tag="VXD01_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0602305.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8300..8617)
                     /locus_tag="VXD01_001966"
     CDS             complement(8300..8617)
                     /locus_tag="VXD01_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0602306.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8632..9528)
                     /locus_tag="VXD01_001967"
     CDS             complement(8632..9528)
                     /locus_tag="VXD01_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV0602307.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9525..10748)
                     /locus_tag="VXD01_001968"
     CDS             complement(9525..10748)
                     /locus_tag="VXD01_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013710989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0602308.1"
                     /translation="MGNNKALVSIRDGITLTIPLLLIGSLLMVIASFPIPGWEKYLGD
                     IGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGIVSLSSFITVTPFIRG
                     EAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMPDGVPPAVSKSFSAII
                     PGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNVIGLLILIFLNSSFWF
                     VGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFMDNFVFIGGGGATIGL
                     VLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIVLNILLLVPFILAPMF
                     NLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLLQIVLIVLDVLLYLPF
                     VIAIEKRFKLLEDCE"
BASE COUNT         3719 a         2173 c         1673 g         3225 t
ORIGIN      
        1 tattaaagtt atataatagt attaatcaaa gaaattgatt ttttgatatt aaaataaaaa
       61 aggagggtag gcagtgttgt gatcaattat tgctggaggt cttattggtc tcttggcagg
      121 taaaatcact aaaaaagtag ttctatggga atcatcgcaa atgtattcgc tggtttagtc
      181 ggggcatatg caggacaatc tcttttaggt agttggggtc catcaatcgc tggaatggct
      241 ttgctcccat ctattgtagg tgcagcgatt gtgattactg tagtgtcatt ctttacaggt
      301 agaaagtaaa cttttcgcca gtaaagttag caaactattt ttaaatcaat gacgggaaaa
      361 atagtttaaa tgttaaatcg aaaggattgt atatgtcaaa agcaaagaaa atatgtttca
      421 ttattttctg tattttaatc ttgacaattt tccttcctgt tttgatagat tatcatcaag
      481 ttagtgatct aggtattcat ctacttagct ggagacagaa ctccgtagtt gaattctatc
      541 ttgctagata tgtcttttgg gggacagtgg ttctatcaac tttagtttta ttatccattt
      601 tagttgtgat gttttatcct aaacgttact tggaaatcca acttgaaact aaaaacgata
      661 cattaaaatt aaagaattcg gcaatcgaag gttttgttag aagtttggtg agtgatcata
      721 gattgatcaa gaacccaact gttcatgtaa atttacgaaa aaataaatgt ttcgttcatg
      781 tagaaggtaa aattcttcct tcagacaaca tcgctgacag atgccaaata attcaaaatg
      841 aaataactaa tggattgaag cagttttttg gtattgagcg tcaagtaaaa cttgaagttg
      901 cagtaaaaaa ttaccaacca aaacctcaaa acaaaaagac tgttagtcgt gtgaagtaag
      961 gaagtaaaaa atggaatggc ttaaacaata tcgatatcca attatcgctg gtctcatagg
     1021 cgtatttctg gcttgtttga ttgtctcctt tggcttcttc aaaacaatat ttgtattgat
     1081 tttaggagca ctgggagttg cagctggatt atatatcgaa aaaaactata tagataaata
     1141 aaaaaataaa aattactaat ttaattaaag gagtttcata tgtcaaacga aaaaaacaca
     1201 aacactaacg tagaaaagaa agatgctact gttgtagctc acgaaatcaa aggggaactt
     1261 acttacgaag ataaagttat ccaaaaaatc attggtcttt cactagaaaa cgtttcaggt
     1321 cttttgggaa tcgatggtgg tttcttctca aatcttaaag aaaaaatcgt taacagcgat
     1381 gacgtaacaa gtggtgttaa cgtagaagtt ggtaaaacac aagttgcagt tgacttaaac
     1441 gttattgttg agtaccaaaa aaatgttcca gctttatatt cagaaatcag agaaatcgta
     1501 tcttcagaag ttgctaaaat gactgacttg gaaattgttg aaatcaacgt aaacgttgtc
     1561 gacatcaaaa ctaaagaaca gcatgaagca gactcagtaa gccttcaaga tcgcgtatct
     1621 gacgttgctg aatcaacagg agaattcact tcagaacaat tcgaaaaagc taaatctggt
     1681 cttggatctg gtttctcaac tgttcaagaa aaagttagcg aaggtgtaga agctgttaaa
     1741 ggtgcagcaa atggtgtagt atctcacgaa aacactcgtg taaactaaga taaaataaat
     1801 ataacaggag aaattatcat gtcagtagaa gaaaaattaa atcaagctaa aggttctatt
     1861 aaagaaggtg ttgggaaagc catcggtgat gaaaaaatgg aaaaagaagg agcagctgaa
     1921 aaagttgttt ctaaagtaaa agaagttgcc gaagacgcta aagacgctgt agaaggtgct
     1981 gtagaaggtg ttaaaaacat gttgagtggc gacgataaat aaggttaaaa gttactttat
     2041 ctttttggta acattagtca aaagagtctg agtcaagatg attctcagaa aacaaaaagc
     2101 tagagattcc caattgcgga actctagctt tttaattttg cctctttctc ttattatatt
     2161 tcagcaggtt gttggccatg agtatgaatc ccatgtcaat tctcacttga cgcttacctc
     2221 tcagatgaca tctcttataa cccaaacaaa cctttatctg cccaaagaca gatttcatat
     2281 caatcttacg tttagcgaaa atttgtctac ccttggaaga taaaagtgcc tgatattctt
     2341 tagtttttaa acactggtaa cgttcattca tatacagtct cttttgaggg gctgattcag
     2401 gttcataatc gcagttaaca ttgatttcaa ggctgtttgc tttctatctc ccctttttca
     2461 tgatatattt tcgtacaggt tcttcaatag tttctatagt aaaatgaacc aaaaatagta
     2521 cacgttgcgg tataatgttc ttgtggcata ttcattagat tttcgtaaac agttctctcc
     2581 tatttgtgag cgaacaggta tagtcaattg attgtcagtt tgaagaccaa gagtcgtaag
     2641 gcaaaggata tggcagaatc catccaaggg tggctggcac aatttctagt gaacctcttt
     2701 aaatctatta cgtttgactg tggaaaagag ttttcaaaat ggaaagatat ttccaatcat
     2761 cacgatagtg agagcttttt tgcgaatcta ggatgttcaa gacagcggtg tctcaacgaa
     2821 cattcaaata gacttttaag gtgtcatgac ttgccaaagc agacagattt caacgaagtc
     2881 agtcaagaat tttaggctgg acaaaaactc aatttcagga gaaaatgaaa taaatattcc
     2941 cacaataaaa cgcatagtat caaagttttt ccaacacctg atattatgca ttttttaatt
     3001 ttaaagactt tttcccagcc tcaagaaatc acatcccacc taaatccttt ggataccaaa
     3061 tacctcatca ggtattttct gagttggtaa gactgtctag cttaatttga caaatggagg
     3121 gcgttaaatc cagtttttac aggaagtcta tttaaatatt ttcacactga ccttacaaaa
     3181 tatgaaataa attatataaa gtcattccca tgacaaagaa taacatccct ttaaaacagt
     3241 atcttaccca attttcaggt aagacttttg atacaaccgt ccccaatacc cctccgcata
     3301 tagaagcaag aaaaataact ggaacaggtg ctaaatgata ctgatttaaa cctgtaacca
     3361 caacaattgt agccaaatga gacagctggg aaaagaaaat aattgcaaga gaatacatcg
     3421 ttgcttcttt tatcgaaata gaaaaaaaca ccatcaataa agatacattg agcggaccac
     3481 caccaatccc taaaaaacta gaaattaagc ccaatagaag accacaaatc atatagaatc
     3541 ctatcttatc aaattgataa gtttttttaa aatctgttaa aacaaatgat acaagtagca
     3601 tcacaaatag taaaatcatt tgaacaatgg atactagccg tactgataac tgagataaca
     3661 aaacttgaaa aataagatga cctagaaatc ctcctaaaac agaagaaaag gataccgtaa
     3721 aaatcaatct ccattttatc tctttacttt gtgaaaatct tttgattgtt gaaataatcg
     3781 ccattataaa aacagagaaa ctagaataaa aagcaatatc actgaccgaa tggtatccaa
     3841 aactatccat aagtggctta attataattc caccacccat gcctgatata gaacccaatc
     3901 cactagctat tataatgatt agaaaataaa taatctcaac cactttttaa gtccatccta
     3961 ttctttcaaa catctaaaac ctagatggct actagtggaa gtagaaatac atccatttct
     4021 agcagctact cggtatcgat tacaataaga acaatgacat aaaaaggaac ctcctctgat
     4081 agcatactcc tcatcttgta tcccatattt tggtaactca tagtcatctt cattaaaact
     4141 agctaataag gtatatctcg gattgcgaca ccattcccaa acattcccaa tcatttgata
     4201 tagaccaaaa tcattaggta aaaattcata gacaggagcc gttcctataa atccatctaa
     4261 ggcagtattt tcataaggaa atcttccttg ccaagtattg gcatgataat atccaccttc
     4321 taaaagagta tctccccaag gatattcaga ttgtcttcct cctctagcag catattccca
     4381 ctgtgcttca gtcggtaaag acattccgct ccaattacag aaagccaatg catcttctaa
     4441 agcaacatga actactggat ggtcttctaa acccactaga ttactattct caccgtaggg
     4501 atgtttccag caagcgttcg gaacttgtaa ccaccacgga gccccagcag gatgagaata
     4561 tccctccctt tctgcctctg gaacgaacaa tataaaaaca aaagaccact cttgtcgctc
     4621 agctagtgtt ttatagcctg tttctttcac aaattgagca aattcttgat tcgtaactgg
     4681 agtatccgca atggaaaaat cctttacact aacagcgact tgaggacctt caaaatcatc
     4741 taaaaagccc tcttcagaat ttgttcccat cataaatgtc ccacccttga tttttttcat
     4801 tttcatgatt gactatcccc cgttttcgtt agagttggcg ttattttaga aagttcaaca
     4861 ggaactaact cttcatccac aacaaaacct tcttctctat atctaagaaa gtctactaat
     4921 tttttcttca tctgacgaac aataggttgg tatttttcac ttggatacaa atcattcatt
     4981 tcatgcggat cttttttcat atcaaataac tgataatgat ttaaaacagg aaaccagata
     5041 aatttccact ggtctgtcaa gatatattga ctagaatctt ttcctaaagc atgttcacca
     5101 tgaaattctg ttcgccaccc ctcgtactgt ccaaataata aattcttaac actccgtcca
     5161 tctagttcat ctgtagtagt tcctcctgcc aaatccacga gtgaaggaaa aatatcttga
     5221 attttcacta attgcttgat tgttccccta ttaccagcta tcaatccagc cggatcgtaa
     5281 ataaacgaag gaatgtggat acttccctga taaggatatc cctttctaaa cagataatgt
     5341 tcaccaagct gatctccatg atccgaaaca aaccagataa tcgtatcttt atcatgacga
     5401 aattctttta gggcagtcaa aaagcgacta atttgatggt ctatatgagt aatcaatcca
     5461 aaataagcag caaccattct tctttgatca tcttccttta atttccctct taaagcataa
     5521 atagacggaa tttgcttttc taatacttcc caattcccga tatgcaaatc gagaaattga
     5581 ggcaagcgtt ccatatacat atcaaaatag tattttgggg gatttaatgg agcatgtggt
     5641 ttttcaaaag acattttgag aaaaaaagga accgttggat ctcttctttg taaaaatgaa
     5701 atggactcac tcacaaccca gtttgttgga tgtaacttct catctttatc ccaaggtcta
     5761 gcttcccaag aattacaatc cattccgtca tcaatcaaat caacatcata accaacttta
     5821 ccctttaaaa aggctagata gtcactagca taatcaaatt gacttccata agccttatca
     5881 tactttctat caacatgtag atacccatcg tgaagtaaga catgatcaaa cccaagtctc
     5941 tgtctggaag gaaaaacatg catcttacca atacactctg tttgataacc catatcttta
     6001 aagacttttg gaagagtatt agtaaaattc caaggcacct catcttgata accaactcgt
     6061 ccacttttat cttggtctaa gccagtcaat aaagctgccc tagcaggaac acaagaagga
     6121 actggagaat aggcattttc aaaattataa cctacactag ccatcatatc taatgttgga
     6181 gtgctaacta gcttatcctt actattcaag gataagacgt ctgctctcat ttgatctaca
     6241 acaatcaaaa taatatttgg ctgttttgtc tgaaccataa aatctccttt ctaatatggc
     6301 aaaagaggca caagaagata tctaccttta ctgcacccct ttctatatca atctctctat
     6361 ataaaacaat aacattcttg ttatgtttta tagaaaaatg aactaaaata tgactaaatc
     6421 gattaggaaa ttcaaatcat tttctagtac tgttttagaa gttacagtgt actattccaa
     6481 cttcaataaa ttataaacct ttgtctaata acaattttag tggagataag aaatcctaca
     6541 cctaactcat cttacacgta atctatttct attttatcac aaaaaacgca agtaagacca
     6601 ttaactcaat tcagttttat ctaccatttt cacaaatggg aaataagtca agacactaat
     6661 aatcaaacaa acaactgata agatgatggc acgccaatca aatgctgtag agaagaaacc
     6721 atataaaatt ggaggcatta cccaagtaac gttttgtgta acaggtgaaa caagacccca
     6781 gcttgttgcc cagtaagcta ccgttgccat gaaaaccggg ctaagtacaa atggtataaa
     6841 tagcaaagga ttcaagacaa ctggtaaacc ataattgacc ggctcaccaa tattaaacag
     6901 aactggtgct agaccaagtt tagcaacttt tcgataatga ctgtttcttg aaaaaattaa
     6961 aatagcaagt actaatccta atcctccaaa ccagacaaac gccccaaaag acccacttgt
     7021 ccatatataa ggaatcggtt cacctttttg gaaagcatcc agattcgcta acatagcaac
     7081 tccaaacagc ccttccatga tgggagccaa tacatttcct ccatggagac caaaaaacca
     7141 gaataactta ttcaaaaaga tcatcagaat aactgcaaag aaactttgag acaaacctag
     7201 taatggcgtt tgtaacacct tgtaaaccca atcaatcaat aagtcattgc taagtaaatg
     7261 gaaaacataa gtcaagatgg ctactatata catcgccata aatcctggaa tgatagaagt
     7321 gaacggctta gcaatcgcag ggggaactga atctggtaac ttgattaccc agttcttttt
     7381 cattacttta cagaaaataa tagaggctaa aaatccaatc atcatggctg taaagtagcc
     7441 tctggcatta atatggtttc ctggaatcac attcccaata gttaccatca gatttttacc
     7501 atcaaatgct agattatcaa ttccttgtaa gatttgatct aatttcacat ctcctacatt
     7561 tgccaaaggg aaactctttg taactgtact tccaatcgaa atgacaaacg aagcaagcga
     7621 taccaaacca gcagaaactg tatcaacctt ataaatctta gcgatattca ctcccaagca
     7681 atagatgaac aataaggaaa caattggtat acttcccttg aataccaaat tattgatgtc
     7741 aacaagccac tgaaaggttt tcgtaatact ttctaggtga aattgttgtg gtaaatccac
     7801 tagaaaagca tttaataaca aagcaatgga acctgtcata ataacaggca tagtccccac
     7861 aaatgaatca cgtaaagcaa ctaaaaactt ctgattccca actttcattg caattggaga
     7921 aagtttttct tgcattttat ccaacattgt attcatagca aattcctaat ttttttcaaa
     7981 tcgttcgtat acttctacca cttctttcgc caagtcaaca aaggtcagac tcgtcattaa
     8041 atgatcttgc gcgtgtacca tcaagaggct aattgatgtt tcttccccct gtgcctcttt
     8101 tgtcaacatt tctgtttgag ccttatgcgc ctgtaataag gcagcattcg catcagctaa
     8161 tcttcgattg gctttagaga aatccccttt ttttgctgcc tgaatagcct ccatagcatt
     8221 acttttggct tccccaccat acataattag ccccattgca gattctaaat tactttcatt
     8281 catagcattc tcctcaatct tagtctaata aactttcagc taaatctaag actttagaac
     8341 cattcatcat tccataatct gtcatcggaa taaccgccac aggaatctgt ctatctttta
     8401 gtttttcttg aaagtcccct agtaaatagc gaacttgagg gcctaaaagc aacacattta
     8461 cttcttttgt tgctacaatt tcttctgctt caggagctgg aactgcaaaa atttctgcat
     8521 ccaacccctt atcttctgct gccttttgca tctttgtcac tagcagactt gtactcatac
     8581 ctgctgcaca tgctaacata attgttactt tagccatagc ttactccttt atcacctatt
     8641 tactgaccta gccaagcgag atactgtatg tctcactcct ctaattgcct tgctcaatgc
     8701 ataaatatta tcgactgttg ccagtccccc atatcctgcg tcacctatat gttgaatatc
     8761 aactccacaa attttatttc taagtgcaat ttccttaata gtatctgtat cagatgtttc
     8821 ttggctagta ccaatagcac tcaatacaag accaccctta ctatgaacga gatcaacgac
     8881 ttcacgcaac tcttggtcat gaaaggctgg aacggttcca actgctggaa caagtatcac
     8941 atccgcacct gcttccaaca attgctctgc gacagaaagc tctgccacag gctcattcac
     9001 tcctgccccg tgcatcttac ctgcaataat caaaccagaa aagttttcct tagcagtttg
     9061 aacagcctta atgatttctc gattgctaac tcctgttcca ggatttccag tcaaacagac
     9121 aaagtcaaaa cctaactcct ctattcgctt caatgtttca acactagcaa cacgacctgc
     9181 aacaatttcc tgtgtttcct ctagcatctt tgcagatggg tcaatcggtt ccaaatttac
     9241 accaattgga caagcaacaa gctggtgtaa gcgatgaata acatcatcac ctgaactatc
     9301 caaagcataa attttaggct caaaaacatc aacacaattc aataaaatca tatcagctcc
     9361 aaaagctcta gcaatttcag aattagttat atccccaaca aatgtctcac gagtaactac
     9421 attttcagat agaacaactc taccttcact tgctaaaata ctttgtttta attcttcagc
     9481 attcatctgt aatatctcag atggatttgc actaattaaa cgtttcattc gcaatcctcc
     9541 aataacttaa accgtttttc aatagctatt acaaatggta aataaagtaa gacatccaaa
     9601 acaatcaata caatttgtaa taatgaacca gaaatacttc ctgtagcaag taaaccactt
     9661 ataacaggtg gcatagtcca acctggatct gtataagtta gcggaaccaa acctgatgcc
     9721 attgctcccc acgctactag taagttaaac attggagcta agataaatgg aactagtaac
     9781 aaaatgttca aaacaatagg aacgccaaac attgctggtt catttatatt aaataatcca
     9841 ggtataacag ttataggtgc caaagttttt agttgtttac tagctttctt cttatgtgct
     9901 aaatatccta acgcaagaac taaacctatg gttgcaccac cgccacctat gaatacaaaa
     9961 ttatccataa atacgctagt aaaaatattt ggaagagttt ctccagtttg ataagctact
    10021 ttatttgcat ctagattagc taaccataac ggtttcataa ctgcattaac aacatttcct
    10081 ccgtgtaatc ctacaaacca aaaactacta ttaaggaaaa ttaagataag aaggccaata
    10141 acattatttc ctaaaagtcc aagtggacct cccaaagcta cttgagcaat ttcatgaaga
    10201 ttaggtaaac ttaatttatc taaagttgca taaacaatca accaaccaac aatagtcact
    10261 gcaccaggaa taatggcact aaagctttta gatactgctg gtggaacacc atccggcatt
    10321 tttatctgta tattatgatt tataaaccat tggtagatat agccattaat caatcctaaa
    10381 atcatagcaa caaataaacc ttttgatgcc atgaaagcgg taggcattcc tgctccagcc
    10441 tctcctctaa tgaaaggcgt aactgtaata aaagatgata atgacacaat accagcagga
    10501 ataccatcaa ctttgtattg tctagccata aagtaagcga taccaaaact agctacaaga
    10561 ccaagtaatc caaaactact atcaacaccc ttccataaat agtcagcaac accaatatca
    10621 cccagatatt tttcccatcc tggaatagga aaacttgcaa taaccattag taatgaacct
    10681 atcaacaata aaggtatagt tagagtaata ccgtctcgaa tagaaaccaa cgctttatta
    10741 ttacccaatc tagccgctac tggaagtaac ttttcttgta ataatttttc
//
LOCUS       DAVLDI010000069        10624 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLDI010000069 DAVLDI010000000
VERSION     DAVLDI010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.069"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(15..1997)
                     /locus_tag="VXD01_001969"
     CDS             complement(15..1997)
                     /locus_tag="VXD01_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV0602309.1"
                     /translation="MKSSRLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGASEPILYKYLELQ
                     DKAITVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2243..3097
                     /gene="rfbD"
                     /locus_tag="VXD01_001970"
     CDS             2243..3097
                     /gene="rfbD"
                     /locus_tag="VXD01_001970"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV0602310.1"
                     /translation="MILITGANGQLGTELRYLLDERNVDYVAVDVTEMDITNSEMVEK
                     VFAEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTENVAKASEKYGAILVYISTD
                     YVFDGKKPVGQEWEVDDIPDPQTEYGRTKRMGEELVENLTSQHYIIRTAWVFGNYGKN
                     FVFTMQSLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYVTENQKEYGYYHLSNDAAEDT
                     TWYDFASEILKDSDVEVVPVDSSKFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALKE
                     FYKQEVRK"
     gene            complement(3159..4205)
                     /gene="rfbB"
                     /locus_tag="VXD01_001971"
     CDS             complement(3159..4205)
                     /gene="rfbB"
                     /locus_tag="VXD01_001971"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV0602311.1"
                     /translation="MTEYKKIIVTGGAGFIGSNFVHYVYNNFPDVHVTVLDKLTYAGN
                     RANIEEILGDRVELVVGDIADAALVDKLAAEADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGLGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQPAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKETIKWYTDNQDWWKSEKE
                     AVEANYAKTQQVIK"
     gene            complement(4217..4810)
                     /locus_tag="VXD01_001972"
     CDS             complement(4217..4810)
                     /locus_tag="VXD01_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV0602312.1"
                     /translation="MSDNFFGKTLAVRKVDAIPGLLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFVAGKLQNNVSFSRKNVLRGLHAEPWDKYISVADDGKVLGSWVDLREG
                     ETFGNVYQTEIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLAEAEVSEADKHHPLLRDVKPLTKDEL"
     gene            complement(4811..5680)
                     /gene="rfbA"
                     /locus_tag="VXD01_001973"
     CDS             complement(4811..5680)
                     /gene="rfbA"
                     /locus_tag="VXD01_001973"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV0602313.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFKDLLLDGSEFGIKLSYAEQPSPDGLAQAFLIGEEFIGDDSV
                     ALILGDNIYHGPGLSKMLQKAAQKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEK
                     PENPRSNYAVTGLYFYDNDVVEIAKGIKPSARGELEITDINKVYLNRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLELAQPLKKN
                     EYGQYLLRLIGEA"
     gene            complement(5821..6648)
                     /locus_tag="VXD01_001974"
     CDS             complement(5821..6648)
                     /locus_tag="VXD01_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIA family hydrolase"
                     /protein_id="HEV0602314.1"
                     /translation="MINKVDYFGMDISDLKNKKLFLFDMDGTIYEEDRLFDGTLQLLE
                     YIQSIGGEYIFITNNSSKSVVDYIEKVNQLGIVAKRENFFTSAQATIVFIEEKYPHAK
                     VYCQGTKSLLKELSDSGIDVTDQVRDNIDLVLVGFDTELTSEKIRNTCEVLSTRDVPF
                     IATNPDVRCPVSFGFLPDCGSICEMISKSVDKTPIYIGKPEPTMVNIVRKKLNYSLSE
                     TVVIGDRLYTDIMTGINAGVSSVCVLTGEATADDIQQGSIKPTYTFRTVKEMWEGII"
     gene            complement(6669..7373)
                     /locus_tag="VXD01_001975"
     CDS             complement(6669..7373)
                     /locus_tag="VXD01_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="HEV0602315.1"
                     /translation="MKALILAAGLGTRLAPITNDVPKSLVPVNGKPILIKQIENLYQN
                     DVTDITIISGYKASVLKDVISGKYPEIKIIDNVDYKITNNMYSAYLGKDAMGSSEFLM
                     MNADVFYDASVIKSLLLHEAPNAIVTDLGTYIDESMKVVEKNGRLVEISKQISPEEAL
                     GASIDVYKFSPDAGACFFEKCREFIEDKNELQLWSEVALNAILQAVEFVACPLDGRWL
                     EIDNHEDLAAAEKLFA"
     gene            complement(7389..8417)
                     /locus_tag="VXD01_001976"
     CDS             complement(7389..8417)
                     /locus_tag="VXD01_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV0602316.1"
                     /translation="MKNNVLKIGSGAIHQISSTLAQNNISGKILYCADPIVDNLYGSL
                     VRSQIEEIGRLKEESCNYNTIAYAMNIAERVIATDIDCIVGMGGGRVLDVCKYASYIS
                     KRPYLSIPTTAANDGIASPVAVLKRQDDRPKSLGAAIPSMTLIDIDVIASGPIQNIKA
                     GIGDTISNYTALKDWELAVNRGKDEMHGFAYLMSQNSLDALMKTKYNSITPDFIEVLI
                     NSLVLSGIAMDFAGSSRPVSGSEHLFSHALDYYGSKRNLHGIQVALGTVAVLKIIEDP
                     ITPVTDYLQRFEVNINPKQMGIDEDLFVYCMQHATTMRNNRYTYLHEADLSTARVKQI
                     YKELVNEL"
     gene            complement(8453..9601)
                     /locus_tag="VXD01_001977"
     CDS             complement(8453..9601)
                     /locus_tag="VXD01_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000636508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HEV0602317.1"
                     /translation="MNILQYIKILARTIFMLLISTVLLPVRLKNNKILFINFNGKGYG
                     DNPKSICEYLRTTYPELDLVWLTKETKGFPDGVRLVKYGSIRAFYEQASSKVWVYNVR
                     AFARILKRKEQFYIQTWHGASSFKLIEKQAELPLNYVLEAKYDARVTDLMISDSKKQT
                     EEYRKYFWYTGEILEVGMPRNDSLFHCKDDYNKLENVRKELNISCDDFVILYAPTFRD
                     NGDISYLNLDFLRLLQSVEKGIRKNCKLLIRLHPNHSQFCRNILFNQDIINVTFFSDM
                     QELILLADVLLTDYSSSIFDFILLNKPYVRYVNDLEEYSKLRGLSDTYYELPDTIIST
                     SEELYTLLPEKINDFDYAAINQYRNGTLSPMFNGRASENIGRRIIQEL"
     gene            complement(9604..>10624)
                     /locus_tag="VXD01_001978"
     CDS             complement(9604..>10624)
                     /locus_tag="VXD01_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV0602318.1"
                     /translation="FYTLNNFLIQYSKGIDKIGVTAISGVISAAVMLSMNILLLVVLN
                     WGLLGFFIANICGYVIPCVYIIVKLKLWDLFELKIDRSLQWEMIYYTLPLILNTLSWW
                     VNNTSDRYIITVIIGIQASAIISVAYKIPQIFSTISAIFIQSWQISAIKIQEEKEGNT
                     FISKMLLYYNALLLIIASGIILFVKPISNILFGASFYSAWTLVPFLIISSLFNAISGY
                     IGAIMGAKMDTKNIAKSALVGMIANVFLNIVLTFLMGLQGITISTMIASFLIFYMRKD
                     SVEEIAPETYRAIYLSWFLLVVEASLLVYIDFIIGATLVTLINLFLLKDTLKPLCLKL
                     LKGFK"
BASE COUNT         3281 a         2221 c         1738 g         3384 t
ORIGIN      
        1 atattttgca acagttattt cacatgtttt gcgagatctt cttgagcctt tttattagac
       61 tcttcttttt ctttcatcca tttttcctga gctttttggt attcatctac agtgattgcc
      121 ttgtcttgaa gttccaagta tttatacaag attggttcac ttgcaccttt atttcctgac
      181 aatgcaaatg gtattgtaaa tggtaccatc ttagacaaga ttgggcgccc tgtacgagat
      241 gtagttggaa taatcaaagc actatctgtc aaccaagctt gggctgcagc gtatttatca
      301 tagcgtttag caacatctgt agcctcatca ccagcctcag tgaccaattt ttcgtagtca
      361 tatagaccta cttttttagc agctacatta tcttcccctg agtcaaaccc taaatatgtt
      421 ttagtacttt ctcctacaga tggtttgatg atatcaaggt aggttgatgg atcggcaaag
      481 tctggacccc aaccgacatt atctgataaa tcccagtctt cgccagcagc attttcagca
      541 aaatatgtaa tattgtttac ttcgtctttt tgtagttgtt ggatatcaat aatgacatta
      601 tcagctccta aagttgcttc caaggattgt ttcatagatt ggacgcgctg aacttttgta
      661 gttgctgtct ggtcaactgg catatccaaa tgaattggga aagtcacacc ttctgcttgt
      721 aaggctgatt tagctttagc aaattcagcc ttggcttttt ctggattgta aagaccatcc
      781 tgagaatctg caagattaac atccttccat tcatccccat aagtgaccaa tttctctttg
      841 accatatcgc caaagttttt accatctgct tgaacaaatg ttggtggcac aaagatatta
      901 cgtaagattt tgcttgctcc agtttgtcca ttcaactgag aggcataggc tgtacgatca
      961 aaaccaaagg caatagcctg acggaaatcc ttgtttaaga gagccttttt agtcgatgcc
     1021 ttttgttcat cgctggtctt agatgtgtat ttataggact gacggtcaat atttgtacca
     1081 actagatacg taatagagtc ttgttgagta tagacaatat tgtccttcat actcttctca
     1141 agctctgcga aacttgcact tgttggatag agacgagctg ctgtaaggct accatcttta
     1201 aagttttctg caggtttgct ggtatcttga ccatcccaga atgacaattt aactttgtca
     1261 acatgcacat tgtccttatc ccagtagttc ggatttttcg caaattcaac agaggatttg
     1321 gtcacaatgg atttcaacaa ataaggaccg ttatacaaga gactacttgg atccgtagct
     1381 ttggcaaaat catctccttt tgaattcaaa aactcttcat taactggcgc aagcacaccc
     1441 atggttgtct tagaattcca gaagctttct ggtttgttca aagtgtactg aactgtctgt
     1501 tcatccagag ccttaattcc tacttgtgag aaatctttga tttccccttt tacataggca
     1561 tccaaccctt tgattgattc ttgaacaagg taaagagcat ctgatttttt atcagcagca
     1621 tattttaatc ctgttacaaa gtcttgagct ttgactgccg cgtattcttc accttcagaa
     1681 gtataccatt ttgcatcctt acggatagta taagtgtaag tcaatccatc cttggataca
     1741 gaccaatcct cagccataga cggcacaaag ttcccgtagc gatcattttc tagcaaacca
     1801 tcaaccacgt tactggtaat atttgctgtc gcagccttag cagttgtcaa atagttgagg
     1861 ttatcagggt ctgtctcata aatgtatgag aatgtcttct cacctttagt gcttgaacct
     1921 gatccagagc atgcagctaa agtagtcgcc gccaataatg tcacgcccgc aagggcaagt
     1981 agtcttgaac ttttcatcat tttctccttt aaaactttct ctctattata gactcttttc
     2041 agagagatgt caatataatt ttctgaattt tttaattaat ttggtaaatt ctgaaaaata
     2101 cttttaagga tattctaaag taataactat tcggctctct tgcgcttcac taacaaagtt
     2161 tataccaaaa aagggttcac taaaaaccga tttttctata tttttgatat aattaagtat
     2221 aagaactatc aaggagaaaa atatgatctt aattacaggt gcaaatggtc aacttggtac
     2281 cgaactacgt tatttactag atgagcgaaa tgtggactat gttgcagtgg atgtgaccga
     2341 aatggatatc actaattctg aaatggttga aaaagtcttt gctgaggtta agccaactct
     2401 agtctatcat tgtgcagcct acactgctgt tgatgcagcc gaagatgaag ggaaagaact
     2461 ggattttgcc atcaacgtaa ctggaactga aaatgtagcc aaggcctctg agaaatacgg
     2521 agctattctg gtctatatct caacagacta cgtctttgat ggaaagaaac cagtaggaca
     2581 agagtgggaa gtcgatgaca tacctgatcc gcaaacagag tacggacgta ccaagcgaat
     2641 gggagaagaa cttgttgaaa accttacgtc acagcattac atcattcgta ctgcttgggt
     2701 ttttggaaat tatggaaaaa actttgtctt taccatgcaa agcctagcca aaacccataa
     2761 aacgctcaca gtggtcaacg accaatacgg tcgcccaact tggacacgga ccttggccga
     2821 attcatgacc tatgtgactg aaaatcaaaa agagtatggc tactatcact tatcaaatga
     2881 cgcagctgaa gacaccactt ggtatgactt tgctagcgag attcttaagg acagtgatgt
     2941 tgaagtagtg ccagtagact ctagcaagtt ccccgctaag gctaaacgac ctctcaactc
     3001 aactatgagt ttggcaaagg caaaggcaac aggtttcgtc atcccaacct ggcaagatgc
     3061 ccttaaagag ttttataaac aagaagtaag aaaataaaag cttactacat actagaaaag
     3121 caagagacct cgaggtctct tgctttttta gtatcttatt atttaatcac ttgttgcgtt
     3181 ttagcatagt tagcctctac tgcttctttt tcagatttcc accagtcttg gttatctgtg
     3241 taccacttga tggtctcttt gaggcctgct tcaaagttgg taaactctgg cttccacccc
     3301 aactcatcac ggagcttgct agcatcaatc gcataacgca agtcgtgacc agctcgatcg
     3361 gtcacatggt cataagcgtc agcgggttgc cccatctcct tgagaatgag ctctaacact
     3421 tccttgttgt tcttctcacc gtcagcaccg atcaagtaag tttcaccgat ttgacccttg
     3481 gtcagaatcg tccaaacgcc tgatgaatgg tcattggtgt gaatccagtc acgcacattc
     3541 ttaccttctc cgtagagttt tggcttgata ccgctcaaga tattcgtaat ctggcgcgga
     3601 atgaacttct cgatatgctg gtatggacca tagttgtttg aacagttaga aatcgttgct
     3661 ttaacaccaa atgagcgcac ccaagcttta acgatcaagt ctgaagcagc cttggttgat
     3721 gagtaaggcg agcttggatt gtacttggtt tcagcggtaa atttctcacc taggccttcc
     3781 ccatgacctg gcaaatcttc acgcagaggc aggtcaccat agacttcatc agtcgataca
     3841 tggtggaaac gaatgtcgta tttacgagcc gcttctaaaa gtgtgtaagt tccgataaag
     3901 ttggtgtgga taaatggact cgggtcattg agcgagttat cattgtggct ttctgccgca
     3961 tagtgaacga tagcatccgc ttcagccgcc aacttgtcta ccaaggctgc atcagcaata
     4021 tctccaacaa ccaactcaac acggtcgcct aaaatttcct cgatattggc acgattacct
     4081 gcataagtca gcttgtccag cactgtcaca tggacatctg gaaagttatt gtaaacatag
     4141 tggacaaagt tagaaccgat aaaaccagct ccacctgtca cgataatttt tttgtattca
     4201 gtcataatgt ttccttttac aactcgtctt tcgtaagtgg tttgacatcc cttaatagag
     4261 gatggtgttt gtctgcctct gaaacctcag cttccgctag attttcccac tcaattccca
     4321 aggatgggtc agcatagttg acaaaggcat atttgggttt tagttcaaga gcccagtagt
     4381 cattgaccag atagctatag gaaactgtat ccgagaggac ttggaaacca ttggcgacgc
     4441 cacgagggac aaaaattccc ttgctagcat caatctctgt ctggtaaaca tttccaaaag
     4501 tctcgccttc acgcaaatcc acccaagatc ctaaaacctt cccatcgtct gcaacagaga
     4561 tatacttgtc ccaaggttct gcatgcaatc ctcgaagaac attttttcga gaaaagctga
     4621 cgttgttttg caatttccct gcaacaaaga agctttcagg aaaaccaagc ggtagcatct
     4681 tttccttctg gaagttttcc ttaaaccaac cacgattgtc tccatgaacg ggaatgtcaa
     4741 actctagcag tcctggtata gcatcaacct tgcgtaccgc aagtgtcttt ccaaaaaaat
     4801 tatctgacat ctatgcttct ccaatcaaac ggagcaaata ttgtccgtat tcattcttct
     4861 tcagaggttg cgccaactcg agcacatctt cacgactgat atagcccatg cgataggcaa
     4921 tttcttccaa gtttgcaact tgaacattct gcatacgctg aaccgtttca atatactgag
     4981 aagcttctag caggctttca tgggttcccg tatccaacca ggcaaaacca cgccccatca
     5041 gctcaacaga aaggtcacca cgatttaggt aaaccttgtt gatatctgta atttctaact
     5101 cgccacgtgc acttggttta atacctttag caatttctac aacatcatta tcatagaaat
     5161 acagaccggt cacggcatag ttggagcgag gattctctgg tttttcttct atggaaatgg
     5221 cattcatatc tgtatcaaac tcgaccacac caaaacgctc tggatccttc acttggtagc
     5281 caaaaacagt tgcacctttc tctttctggg ctgccttttg aagcattttg ctcaaaccag
     5341 gtccatgata gatattgtcg cccaaaatca aggcaacact atcgtcaccg ataaattctt
     5401 caccgataag aaaagcctga gcaagtccat ctggactagg ttgttccgca taagaaagct
     5461 tgatcccaaa ttcggaacca tccaagagca agtccttaaa ccggggcaaa tcttgaggag
     5521 ttgagataat caaaatatct ttaattccag ccaacattaa tgtcgacaac ggataataaa
     5581 tcataggttt atcataaacc ggcatcagct gttttgacgc agcccgagta agtgggtaca
     5641 ggcgggtacc tgagccgcct gcaagaataa tacctttcat aatagtgtac ctttcttttt
     5701 tgataagtct tttactttga caaaccacta ggaggaaagt aaattttaat tgtccatact
     5761 aaattgctat taacatttca aggtcatatc cctaagttta taaatcaata acctagagaa
     5821 tcatataatt ccttcccaca tctctttcac agttctaaaa gtataagtag gctttatact
     5881 cccttgttga atatcatcag ctgttgcttc tcctgttaat acacatactg aggatactcc
     5941 tgcattaata cctgtcatga tatcggtgta taaacgatca ccgattacaa ccgtttctga
     6001 caaagagtaa ttcaattttt ttctaactat gttaaccatc gtcggttcag gtttaccaat
     6061 ataaatagga gttttatcaa ctgatttgct aatcatttcg caaatcgaac cacaatctgg
     6121 aagaaaacca aaggaaactg ggcaacgaac atctggattc gtggcaatga atgggacatc
     6181 tctcgttgac aaaacttcac aggtattacg gattttctca cttgttagtt ctgtatcaaa
     6241 accaactaaa acaagatcta tgttatctct cacttgatcg gtaacatcga ttcccgaatc
     6301 ggatagttct tttaacaatg atttcgttcc ctgacaatac acctttgcgt gaggatattt
     6361 ttcctcgata aaaacaatcg ttgcttgagc agaagtaaaa aaattctccc gtttagccac
     6421 aatacctaat tggttaactt tttcaatata gtcaacaact gactttgagg aattgttcgt
     6481 aataaaaata tactcaccac caatactttg aatatattct aataactgaa gtgtcccatc
     6541 aaacaatcta tcttcttcat aaatggtacc atccatatca aataaaaata attttttatt
     6601 ctttaagtca ctgatatcca tcccaaaata atcaacttta tttatcaaat ctgtcctccc
     6661 tatttgtttt aagcaaatag tttttcagct gcagcaagat cttcatgatt gtcaatttcc
     6721 aaccaacgcc catccagcgg acaagctacg aattcaacag cttggagaat cgcattaagt
     6781 gcgacctcgc tccacagttg aagctcattt ttatcttcaa tgaactctct acatttttca
     6841 aagaaacaag ctcctgcatc aggagaaaat ttataaacat caatagaagc tcctaaagcc
     6901 tcctcaggtg aaatctgttt agaaatttct actaaacgac cattcttttc tacgactttc
     6961 atagattcat caatgtaggt tcctaaatca gttacaattg cgttcggagc ttcatgaagt
     7021 aacaaacttt taatgacgga agcatcataa aacacatctg cattcatcat taagaattca
     7081 ctactcccca ttgcatcttt acctagatag gctgagtaca tattatttgt tattttataa
     7141 tcaacattat caataatctt aatttcaggg tatttcccgg aaattacatc ctttaatact
     7201 gatgccttat agccagaaat aattgtgata tctgttacat cattttgata taaattttca
     7261 atttgtttta taagaatagg ttttccatta acaggaacta atgattttgg gacgtcatta
     7321 gtgataggag ccaaacgtgt tcctaaacct gctgctaaaa taagtgcttt cattttttcc
     7381 tctcttttct acaactcatt tactaattct ttatatattt gtttcaccct agctgtgctt
     7441 aaatcagctt catgaagata tgtatagcga ttatttctca ttgttgtagc atgttgcata
     7501 caataaacaa ataggtcttc atcgattccc atttgttttg gattgatatt tacctcaaat
     7561 ctttgcaagt aatccgtcac tggtgtaatc ggatcttcaa ttatttttaa tactgcaact
     7621 gtacctaatg caacctgaat accatgaagg tttctcttgg aaccataata atccaaggca
     7681 tgactaaata agtgttctga accactaact ggtctactac ttcctgcaaa atccattgca
     7741 atacctgata aaactaatga atttatcaaa acttcaatga aatcaggcgt aatagaatta
     7801 tactttgttt tcatcaaagc gtccaaggag ttttgggaca ttaaataggc aaagccatgc
     7861 atttcatcct tgcctcggtt aacagctaat tcccaatctt tcaacgccgt ataatttgaa
     7921 atcgtatcac caatgcccgc tttaatattc tgtatgggtc ctgatgcaat aacatcaata
     7981 tcgataagag tcatagatgg aattgccgca cccaaacttt taggtctatc atcttgtctt
     8041 ttcaaaactg ctactggaga agctatccca tcattcgctg cagtggtggg aattgataaa
     8101 tatggccgtt ttgaaatata agatgcatat ttacaaacat ctaaaacgcg accacctccc
     8161 attcccacaa tacaatcaat atctgttgca ataactcgct cggctatatt cattgcgtaa
     8221 gcaatcgtat tataattaca actttcttct tttaatcgac ctatctcctc aatttgtgac
     8281 ctaactaaag agccatatag attgtcaaca attggatcag cacaatatag aatcttacct
     8341 gatatattat tttgagcaag tgtagaggat atttgatgaa tagccccact gcctattttt
     8401 aatacattat ttttcaaacc ttttcaccta aaaaataatt caatgatttt ctttacaatt
     8461 cttgaattat tctccttcct atattttcac tagctcttcc attaaacatt ggactaaggg
     8521 ttccatttct atattgattt atagcagcat aatcaaaatc atttattttt tcaggcagga
     8581 gggtatacag ttcctccgat gtcgaaatga tagtgtcagg tagctcataa tatgtatccg
     8641 ataatcctct aagtttagaa tattcctcaa gatcattcac atatcttaca tacggcttat
     8701 ttaagagtat aaaatcaaat atagatgaag aataatctgt tagtagaaca tctgccaaca
     8761 atatgagttc ctgcatatct gaaaagaatg taacattaat tatatcctga ttaaataaaa
     8821 tatttctaca aaattgtgag tggttaggat gcaacctaat taataattta caattctttc
     8881 taattccttt ttccacactc tgtaacaggc gtagaaaatc taaattcaaa taggatatat
     8941 caccattatc tctaaaagtt ggtgcatata aaatgacaaa atcatcacag gagatattaa
     9001 gttcttttcg aacattttct aacttattat aatcgtcttt acaatgaaac aaggaatcat
     9061 ttcttggcat ccctacctca agaatttcac cagtatacca aaaatatttt ctgtattcct
     9121 cagtttgctt cttactgtct gaaatcatta aatccgtcac tcgtgcatca tatttagctt
     9181 ccagaacata gttcaaaggt aattcagcct gtttttctat cagtttaaaa cttgaagcac
     9241 catgccaagt ctgaatataa aattgctctt ttctttttag tatcctagca aacgccctca
     9301 cattatacac ccatactttt gaactagctt gttcgtaaaa agctcgaatt gaaccatatt
     9361 ttactagtct gactccatct ggaaaccctt ttgtttcttt agtgagccat actaaatcta
     9421 attctggata tgtagttctt aggtactcgc aaatactttt aggattatca ccataaccct
     9481 tcccattgaa attaataaat agaatcttat tattttttaa cctgacaggt aataacactg
     9541 tacttatcaa tagcataaaa atagttctag ccaaaatttt aatgtattgt agaatattca
     9601 ttttcattta aatcctttta ataattttaa acataatggt ttaagagtat cctttaataa
     9661 aaataaattg attaatgtaa ctaatgtagc cccaataata aaatctatat aaaccaaaag
     9721 actagcctca accactaaca aaaaccacga aagataaata gctctatatg tttctggagc
     9781 aatttcttca acactatctt ttctcatata aaaaataaga aaactagcta tcatagttga
     9841 gattgtaatc ccctgtagtc ccattaaaaa tgttaataca atatttaaaa aaacattagc
     9901 tatcattcca accaaagcag atttagcaat atttttagta tccattttag cgcccattat
     9961 cgctcctata taacccgaaa tcgcattaaa caaactgcta ataattaaaa acggtacaag
    10021 cgtccacgct gaataaaatg aagctccgaa gagtatatta gagattggtt ttacaaatag
    10081 aatgataccg ctcgctataa tcagcaagag tgcattataa tataaaagca tttttgatat
    10141 aaaggtgtta ccttcttttt cttcctgaat ttttattgca gatatttgcc acgattgaat
    10201 gaatatagcg ctaattgtgg aaaaaatttg tggaatctta taagcaactg aaataatcgc
    10261 actagcttgt atacctataa ttactgttat aatataccta tctgaagtgt tattaaccca
    10321 ccaacttaaa gtatttaaaa tcaaaggtaa agtataatat atcatttccc actgtaacga
    10381 tctatcaatt ttaagttcaa ataaatccca taattttagt tttactatta tatatacaca
    10441 aggaatgaca tacccacaaa tatttgcgat aaaaaaacct agtagtcccc aatttaatac
    10501 cactaacaat aaaatattca tcgaaagcat aactgctgca cttatgactc cagagatagc
    10561 cgttacacct attttatcaa tccctttaga gtattgtatc aaaaaattat taagtgtata
    10621 aaaa
//
LOCUS       DAVLDI010000070        10621 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLDI010000070 DAVLDI010000000
VERSION     DAVLDI010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10621
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.070"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(137..1561)
                     /locus_tag="VXD01_001979"
     CDS             complement(137..1561)
                     /locus_tag="VXD01_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV0602319.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEATSKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVAEKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2106..4385)
                     /gene="pulA"
                     /locus_tag="VXD01_001980"
     CDS             complement(2106..4385)
                     /gene="pulA"
                     /locus_tag="VXD01_001980"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV0602320.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4497..6455)
                     /gene="ligA"
                     /locus_tag="VXD01_001981"
     CDS             complement(4497..6455)
                     /gene="ligA"
                     /locus_tag="VXD01_001981"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV0602321.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTNLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6548..7726)
                     /locus_tag="VXD01_001982"
     CDS             complement(6548..7726)
                     /locus_tag="VXD01_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV0602322.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLQSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7806..8669)
                     /locus_tag="VXD01_001983"
     CDS             complement(7806..8669)
                     /locus_tag="VXD01_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV0602323.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGLALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8672..10573)
                     /locus_tag="VXD01_001984"
     CDS             complement(8672..10573)
                     /locus_tag="VXD01_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV0602324.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKVTAEMSQTEEASTSNQAKEASPVNDYQVQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3184 a         2340 c         1904 g         3193 t
ORIGIN      
        1 caatgtttta gaagtagagc tgtactattc tagtttcaat atactataat accaaaaagt
       61 tcgtattttt tctataatta ttattatttt atagcaaaaa aataaaacca ggaaaacaat
      121 ttcctgattt tacacgttat ttcacatcaa aaacaatgga tttgacattt gtcatcgctt
      181 caatgctata tttaattcct tgcactccag ctccagaacc tttgacacca aggaatggga
      241 aattatctgg accacgctgg gttttattat taatgtggac tgtacctact tcaagttttt
      301 cagcaatttc aaaggctttt ttgaaatcat ttgtaaagac tgatgattga aggccgaatt
      361 cagattcgtt ggcaaaggca atagcttcct ctacactagc cacacgaatg attggtaaaa
      421 caggaccaaa tggctcttcc catgccactt tcatatcttt tgtaacttgg tcaaaaagca
      481 ctggccagag gagattgccc tcacgtttga ttggtgtaag agcctgagcc tctttttctt
      541 gtgcatcctc aatcaagccc caaatgaagt cggctgaagc attgtcaata acaggtgtaa
      601 tatcagcatt gtcaaatgga tcaccaactg ttaatttaga aacttcttcc tgaagcaaag
      661 tagctaattt ctctgctaca ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt
      721 gtcctgagta gctaaaggct cccgcaacaa tttgcttggc agcatgttcc aaatctgcat
      781 cttctagtac aagagctgca tctttcccac caagttccaa catgatagga cgcataccag
      841 ctaaacgacc aatacgttct ccaataggag ttgaacctgt aaagttgatg aagttgactt
      901 ctttgtgctc aatgatataa tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa
      961 cacctgccgg aatccctgct tcttcaaatg ctttagccaa caagagtcca gaaatggaac
     1021 cttgtgttgg tggcttaaac atgaccacat tccctgcaat caaggcaggt gcaattttag
     1081 aagcagataa attaactgga taattaaagg gagcaatcgc tagcacgata ccaactggtt
     1141 cacgacggac aacagccagt ttgtttttac ttgttgcctc aaaaccacca ccttccattg
     1201 cttgtccagt gatacggaga ccttcctcag cagcataacg aatcaagtct gctgtacgca
     1261 ctacttctcc aattgctgct ttaatccctt ttgctacttc tttggcaagg atagtaccaa
     1321 tttcttcctt atcgcgttct aaaatagctg ctgttttatg caaataagcc gcacgttcaa
     1381 ctgctgataa agctcgccat gctggcaggg ctgcacgcgc agcttgcata gcctcatcag
     1441 cttcagtctg agtcatggct ggaactgtac ccaattcttc ttgattgatt ggtgaataaa
     1501 tcgtaatttc ttgttcagat gatttccatt ttccatttac taaattctga tatcttgtca
     1561 aattcttgtc ctcctgaaaa tgattaagat atattttacc aaattttcag aaaatcacaa
     1621 ccctttttgc aaaatttttg agattatttt cacaaacttg atttttcaaa gtatactcaa
     1681 taaaaattaa aaaaatccac tacgtcaagg cgaggctaat gtggtttgaa gaaattttcg
     1741 aagagcgtga atgagtatca tctatagtaa aataaaaaaa ctgaacaatt tggttgggga
     1801 cagccaaacc aatttctcac aatgttttag aaacaagggt gtgctattcc aatttcaggc
     1861 tactataact gtcatagatt gctgaaacaa agtctaggta aaagtcttca taataaaaag
     1921 accccctatc aagtgttcaa aaactttgat aggaggtctt gttttgtgaa aatatttatc
     1981 aaattttcta tacaagtgag ctgttagcca ggttctttct attctttcaa tttcaatgaa
     2041 tggatttttt actaatactc ataactggga atttgtctgt gtaaaaatag cgagatagat
     2101 ggtatttata aaacactcaa gacagctaga ctaatatcat ttaaaacatt atcttctttt
     2161 gagcgactgt tggttaccaa catagctaaa tttcctgcat tttcaaattg atagggttct
     2221 gatttagcat tcacaaccac caagagatgt tctttgccgt gaacttcata gataaggtag
     2281 ccgctatgtt caatcgcaga atgcacaaag acatgatggt aaatttcatc atagctagag
     2341 taagaaaagg caccagtttt tgtcttcaat cggatgactt gacggataaa ctcaatactg
     2401 tcttgacgct cattaatcaa gttccagttc acttggttca cactgtcagg agcattatag
     2461 ctattcatcg cacgctctct atcatcatgg gtcaactcac cattttcacc agtcgcaacc
     2521 agtttggtac gaccaaattc ttgaccgatt tccataaagg ccatcccctg catgagcaga
     2581 ttcatggctg tggcagtttc gaccttgcgc atgatttgct ctgaactttg gtctggatga
     2641 agggttgcca ataaatcgtg aagattgtaa ttgtcatggg cttctacata gttaagcacc
     2701 tgatttggat gtgtatagct tcctaattca cgacttccta ggattgcttt agctagaatt
     2761 ggctctgtcg cagcaccact gacaaaacct gacttgatag caccataaac ttctccccct
     2821 ttgacagcat cgcgctgatt gtcattaaag aaaccaatat ttggcatctg gtaggcattg
     2881 tccttcttgg ccttatcata aggggcaaga cctgttccca tatcccatcc ttctccatag
     2941 aggataatgt tggagtcgat ttcatccaag ctttgacgaa tcatctgcat ggtcttgaca
     3001 tcatgaatcc ccatcaagtc aaaacggaag ccgtcaatat tatattcctg cacccagtat
     3061 agaagagaat caatcatata cttgcgaaac atttcgtgtt cactggctgt ttcatttcca
     3121 acacccgttc cattctggaa ggtaccatct ggattcatac gataatagta atcagggact
     3181 gttgtttgga atggtgcatc aacaactgag aaggtatggt tatagactac atccataatg
     3241 actccaatac ccgcatcgtg ataagcttga accatcacct tcaaatcacg aatgacctga
     3301 gctggatcat ctggattagt tgaaaaacta gtttctggcg cgttatagtt ttgtggatca
     3361 taaccccagt tgtaggttac atttccatcc tcatcgtatt ctttatgacg gtctgcaatt
     3421 ggttgcaatt gaacataatt gtagcccagc ttcttgatgt aatcaaaagc agttgactgg
     3481 ccgtattggt taactgttcc agcctgagca gcacccaaga aagttcctcg aagatgttca
     3541 tctacacccg atgtaggtga tttagtcaaa tcacgaatat gcatttcaca gataactgcc
     3601 ttacatggat tttccaagcg ccaagtagcc tccgaaccgt gcttaacctc gaagttttca
     3661 acttgctttt ctacatggct cagaatagct gaacgtttgc catcagggct ggtcgcgatt
     3721 gtataaggat cacgtgtcag tgtttggtga tgagggaatt ggacttgata ctgataagtc
     3781 ttacctacca aatcttcttc aacatccaaa ctccagacac cgattgtatt gtccttatga
     3841 ttataagagt agctattgcc tcttttcatc tcaaaagtct tccaaacggg tgcatcatta
     3901 gcagctgatt cataaacgac aacttgcact tctgtcgctg taggtgacca gagggaaaaa
     3961 tgagcctgat tgtcctctac acggcaaccc aattctcctt ggtaacccca atgatgatca
     4021 aaactagcac tgttaatggc cttatcaaag gcaaaaggat tttgattttt atagaaagga
     4081 ctggcaatag caggattttc agagtaataa atcctatcat cgccttccaa aatccagacc
     4141 tctgttaata ggggatagtg attaaaacgg atagaatatt ctttactagt ttgacctgta
     4201 tgaaccacaa aattcaagct ttctataaca tgtgaacttg ggtgttcaaa gctaaataaa
     4261 gctccaaaat aatcttcttt gtaggttagc aaatcaattc gttgatcctg actttttaca
     4321 aaggagcaag tgtcatattc tccattctta cgatggtaat gaatgcgcat agggtagtta
     4381 tacatttttt atttttcctt tttactttgt ttctatttca ctaataaatt tttgtcaatc
     4441 tcgtctcaat taacagacat agtcatattc tctaaactct gtttttaaac gatccattac
     4501 aaactttcta gccatgcctc atctctgacc tggataccaa gttcttgtgc tttttgcagc
     4561 ttacttccag cgtctgcacc taccacgacg aggttggtct ttttagaaac actacctgtc
     4621 actttggcac ccagactttc gagtttactt ttagcttctg agcgcttgag tcgttccaat
     4681 tttcctgtca ataccacggt caaacctgac aaggccgcat ccgctactac cgtctgtcct
     4741 ttatagtcca gattgacccc agtttctttc aattctctga gcagaatttc agagccttct
     4801 gtcgcaaaat aagtctgaag acttttggca atcacgccac ctagactttc aatactagcc
     4861 acttcctctg aatctgcctg atacagattt tcaattgaat ggaaatattg aagtaaaagc
     4921 tgactagcct tgcttccgac atgacgaatt cccaaaccaa ataagagctt ctcggcagaa
     4981 ttttcctttg acgcttggat agcctgatac agtttagcag cggacttttc cttaaccccc
     5041 tctaaaagga ggaaatcctc ttcttgcaaa cgataaatat ccgccacatc cttgactaaa
     5101 ttagcagcaa aaagcttctc aacaatagat ggaccaaggc ctgtaatatt catagcatca
     5161 cgagaagcaa agtgaatcaa gccttccatg atttgagcag ggcaacgcgg attgatacaa
     5221 cgtagggcca cttcatcttc aaagtgcaac aagtcagagt tacaacttgg acagtttgta
     5281 gggatatcta gtttttcttc agaaacccgt ttggactcta ccacacgtaa aacggcaggg
     5341 atgatgtcac cagccttata tacaatgacc gtatcgtctt ttcggatatc tttttcagca
     5401 atataatcta cattgtgcag ggtcgcacgg ctaacagtcg taccggcaag ttgtactggt
     5461 gttagattag cagttggagt tacaacaccg gtacggccaa ctgtccagtc aactgataag
     5521 agttgagctt ctttttcttc agcagggaac ttgtaggcta ctgcccactt tggagcctta
     5581 acggtaaaac caagttcttc ttgacttgct aggtcgttga ccttgattac cactccatca
     5641 atatcgtaag gtagattttc ccgttcctgt cctacttctt ggataaaatt ccagatttca
     5701 tctatgtttt cagccaagat tcgcttagga ttgaccacaa aacctagttg ttctaggtac
     5761 ttcaaaccct tttcttggct atcacgagtt gaagggctgg cttcttgata gagaaacgtt
     5821 gcaagattac gcttggcaac tactgctgta tccaactgac gcagagttcc tgctgccgca
     5881 ttacgaggat tagcaaattc aggctctcca ttttcttggc gcgcttggtt aacttggtca
     5941 aaggaagcgc gtggcatgta acattcccca cgaactgtga tatctagttc ttctggcaaa
     6001 gtcaaaggga tgtccttaac acgcttgagg ttttctgtga tattttcacc aattgaacca
     6061 tctccacgtg ttaccccagc aaccaaaatc cccttttcat aagtcagcga gatagataag
     6121 ccatcgattt tcagctcaca aatataggtc ggatgagcca cttccttacg aacacgcgca
     6181 tcaaaagcat ctagctcctc acgtgaaaaa gcatcctgca aactataaag aggatactga
     6241 tgactgtatt tttcaaaacc atctaaaacc ttgccaccaa cacgatgagt cggactgtct
     6301 gctagcactt gctctggata agcagtttct aactcgacca actcacggta aaggcggtca
     6361 tactcactgt ctgaaaccga gggattatcg ctggtatagt actcagtcgc atagcgattg
     6421 agcaaagcga ctaactcatt cattctttta ttcataagac cattttacca taaaacaagc
     6481 cctcctcaca aacgagaagg gcggaaaaaa cacttagttt gaaattattt ttgaaactca
     6541 agcaacctta tatcaatttt tcaaaatgag ttcgaacata aataaacgat atacaagaca
     6601 agatgataac accacttcca attatcagga aagaagagag atgtacactt tgcaagactg
     6661 tcataaatcc ttttgcaata ggcataaata gaatagctaa ggtaaaaatt gtactcagta
     6721 ctctcccaag aaattcgctc tcaaccttgg tttgtacttg agtaaaaaag tgaatattaa
     6781 aaatcgtcat aaacaattca caaactaaat ttccagaaaa ggaaagaaaa gttggaagtg
     6841 gtaatcccat cataaaaact ccaacacctg tcaaagccag taaaatcaaa agattataaa
     6901 tattagcttt aattttacta gctagaagag ccccaatgat ggaaccaata gcccccatag
     6961 ttaaaatact tgcataggct ccttctgacc cgtaaagctg attcgaaaag ggaagtagaa
     7021 attcaaaagc tgcaaaaaag aaattaacgc tggaagctac cagcaaaagg aagaaaattt
     7081 cttgctgatg ccagatatag tgtaacccat ccttgatatc tacaaaaata tctctcccag
     7141 taaaagcctt tttctcttga acttttgctt cctcttttgg aaggaaagcc actagaacaa
     7201 aagcaatgaa aaaagtcagc gagtctagca gtagcgtcat atggagactt gcaaactgta
     7261 aaacaaggaa ggaaagaaca ggagagctaa cacctacaac ctgcaaaacc agctctaagc
     7321 gagaattata gatcacaatc tcatctttct ccaccacttc agttatgata gctttattgg
     7381 ctgtgcgaga aaaggcaaaa gcaatagcct gcacaatgtt agcaacaatc aaagcgccaa
     7441 tcatccagct atcattcctt atgaaagaaa tagccagaca aagaatccca caaacaagat
     7501 ctgccgtcat taaaatctta cgacgagaaa aacggtctga aataactcca ccaaagggat
     7561 tgacgagaat agatgtgacg agctcagaaa tctgatacat tcctaaaact gtctgtccta
     7621 tagtccccat agaagccaac cagacactat ttccataatc atagagcata tttcccattt
     7681 tattgatagc cccacggcta atcaactgca ctgcatagcg attcatatta aagctcctct
     7741 caaattttga aactattgta tcaaaaccga aaggagcttt ttattttttc ccttatttgg
     7801 gaaaattaac ttttgacaaa tttttcgtag tgttcctgat aataggctac ttgctctgga
     7861 agacctaaca catcaaaaat atgcatggcc tcttgcatct gcttacagcc ttctttacac
     7921 tgtccttttt gatataaggc caaacctttt aaataatgga aaacattacg ctcataaagc
     7981 ttaatacctt tgtcaataat cttctctgta taagcctcaa aatagttggc attataaaaa
     8041 gaagaatgct ctaaacaatg ctggtaacaa ttgagggcca aaattaacac taatctctta
     8101 tggcgactaa tctcttggta aaattcctcc ctctccataa cttctctacc aatccgagtg
     8161 acatagtcta catcgtagaa actatagagg ttaccgaaaa gaatcaactc atacatggtc
     8221 cattcttctg ttttgaagag ataatctgct accttatcca aatcatcctg cttcatatca
     8281 taactcgcat ctctttgaca aatcagacct tgtagcaaaa tccagttcag ctcaaaataa
     8341 aggggagtcg tcgaactctt agacttttca agttgttctc tttgaagctt ttgaaaacct
     8401 gcaatatcgt ttgaatagta aagtgggata atctgtgcca tcatagacac atgttcatga
     8461 ttatgaaaat tccttgcctt atccatgaaa ttttcgattg ttacatgaat gttatccaaa
     8521 atctcaaaga aacgggagac tgccaggtca gactccccaa gctcaaagcg agataactga
     8581 gaggtagagc aggattcgcc tgctgcttcc tttaaagaat aatttccact tgttcgaaat
     8641 tcacgaaata cttttccaag atgttccatc tttacacctg ctctgataat tcttcccact
     8701 caagcatagc ttcttcctga cgatggctga ttttgtccag ctcagcctgt aattccatga
     8761 gtttgtcggc atcgtttgtt tccaacattt gttcagaaat ggcttggctt tgactttcta
     8821 gctcttcaat ttcagcttct agactttcga tttgtcgcat gagtttgcga acttcttttt
     8881 gactttcttt ctggacctga tagtcattga ctggacttgc ttcctttgct tgattgctag
     8941 ttgaagcttc ctcagtctga ctcatttctg ctgttacttt cttctcaaca tagtagtcgt
     9001 aatctccaag gtagagagtt gaaccattct cagacaattc caaaacatga gttgccacac
     9061 gattgataaa gtaacgatca tgactgacaa acagcaaggt accatcaaag tcaatcaagg
     9121 cattttctag cacttcctta ctatcaatat ccaagtggtt ggtcggctca tccagaatca
     9181 aaaagttatt gttttccata gacaatttag ctaaaagcaa acgagctttt tcgccaccag
     9241 atagcatgcc gactgatttt ttaacatcat ctcctgagaa aaggaaggct ccaagacggt
     9301 tgcggatttc aacttctggt gtcagtttga aatcattcca gagttcatcc agcaccgtat
     9361 tacttggtgt cagcttgctt tgggtttggt catagtaacc aacctcaaca ttagcgccaa
     9421 agcgcttttc tcccttgata aacggaattt gatccacgat tgatttgata aaggttgatt
     9481 ttccgatacc attgggacca acgatagcga cagcattcat cttacgaaga tctaggttga
     9541 taggttgtga caagacttcc ccgtcataac caatagcagt attttcaaca gtcaaaacaa
     9601 cattgcccga cgttttttca gactggaagg tcatgttggc tgctttcttg ccagcttcag
     9661 gcttgtccaa acgctccatt ttttctagtt gtttacggcg agattgagca cgtttagtcg
     9721 ttgaagcacg aactagattg cgattgacaa agtcttccag agcagcgatt tccttctgtt
     9781 gcttttcata gttttttgcc tcagtagcta gcttttgctc cttcaattcg acaaaacgag
     9841 agtaattccc cacatagcga tccaaggaat gcttggtcaa atctagcgta attgtcgcaa
     9901 ccttgtccaa gaaataacgg tcgtggctga cgataatgag ggcaccgcta tagtttacca
     9961 agtaattctc tagccaggag atggtttcaa tatccaagtg gttagttggc tcgtccaaga
    10021 ccaagagatt gggcttttca aggagcattt tagctagagc caaacgagta ttttgaccac
    10081 ctgaaagttc agctattttc atctgccaca tagactcgtc aaacttgaat ccattcaaaa
    10141 tcgctcgaat atcagcttca taggtaaagc cgcctgcttg gcgaaaattc tcagataagt
    10201 ggtcgtaatc tgacatcagt ttatccaaat cctcaccaga cttttcaccc atctccaact
    10261 ccatctgacg aagttgttta tctgtccgac gtaagtcatt aaagacatga agcatttcat
    10321 cgtagatggt attttcagac tcaaaacggc tatcttgggc taggtaagac agagaaatat
    10381 cttttttctt attgatttct ccgctagttg gctcctcttc tccaactaaa atcttcaaaa
    10441 gagtagactt acctgcacca tttttcccaa caagggcaat ccgatctcgt tcatcaacct
    10501 gcaggttgat attatcgaaa agaacctctc ctgcaaaaga acgttcaatt ttattagctt
    10561 gtaaaataat cataagagta gtatagcatg tttccctaag gcattcaaga taatcgtaag
    10621 t
//
LOCUS       DAVLDI010000071        10293 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLDI010000071 DAVLDI010000000
VERSION     DAVLDI010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10293
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.072"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..363
                     /locus_tag="VXD01_001985"
                     /pseudo
     CDS             1..363
                     /locus_tag="VXD01_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            263..709
                     /locus_tag="VXD01_001986"
     CDS             263..709
                     /locus_tag="VXD01_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0602325.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFTRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVDHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(847..2151)
                     /gene="eno"
                     /locus_tag="VXD01_001987"
     CDS             complement(847..2151)
                     /gene="eno"
                     /locus_tag="VXD01_001987"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV0602326.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2315..2761
                     /locus_tag="VXD01_001988"
     CDS             2315..2761
                     /locus_tag="VXD01_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV0602327.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2758..3874)
                     /locus_tag="VXD01_001989"
                     /pseudo
     CDS             complement(2758..3874)
                     /locus_tag="VXD01_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(3883..4528)
                     /gene="serB"
                     /locus_tag="VXD01_001990"
                     /pseudo
     CDS             complement(3883..4528)
                     /gene="serB"
                     /locus_tag="VXD01_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084485.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
     gene            complement(4587..6020)
                     /gene="glgA"
                     /locus_tag="VXD01_001991"
     CDS             complement(4587..6020)
                     /gene="glgA"
                     /locus_tag="VXD01_001991"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV0602328.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6017..7156)
                     /gene="glgD"
                     /locus_tag="VXD01_001992"
     CDS             complement(6017..7156)
                     /gene="glgD"
                     /locus_tag="VXD01_001992"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV0602329.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7146..8288)
                     /locus_tag="VXD01_001993"
     CDS             complement(7146..8288)
                     /locus_tag="VXD01_001993"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV0602330.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVTTDED"
     gene            complement(8278..10206)
                     /gene="glgB"
                     /locus_tag="VXD01_001994"
     CDS             complement(8278..10206)
                     /gene="glgB"
                     /locus_tag="VXD01_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV0602331.1"
                     /translation="MDNREALKTFMMGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDIYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNIEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3116 a         2270 c         1821 g         3086 t
ORIGIN      
        1 aattttaata gtttaaagca cctagcacag gtctaacaaa taaatggtga gttaatcgct
       61 ccaatgattt acgaagagac gatgacgagc gacttttttg aagcttggtt tcagaagttt
      121 ctcttaccaa cattaaccac accatcggtt attattatgg ataatgcaag attccataga
      181 atggggaagc tagaactttt atgcgaagag tttgggcata aacttttacc tcttcctccc
      241 tactcgcctg agtacaatct tattgagaaa acatgggctc atatcaaaaa gcacctcaaa
      301 agggtattac caagttgcaa taccttttac gaggctcttt tgtcttgttc ttgtttcaat
      361 tgactatata aattgtctaa gcgaaacaac cgataagaat tggcacaaaa gcgaccgtat
      421 ttttgttacc aatacaggaa aaccagttca tagttctatc ttgagcaagt ctctccagcg
      481 agcaaacgaa cgccttaaaa aaccaattcc caaacatctg tcccctcaca tcttcagaca
      541 caccactatt agcatcttat cagaaaataa aattccttta aaaacaatca cggacagggt
      601 tgatcattcc gactctgaag tcactacttc catctacacc cacgtcacaa agaacatgaa
      661 agatgaagca atcaatgtac tggataaagt tatgaaaaag attttttaaa aagttttgtc
      721 ccttttttgc cctctaaata caaaaatagc ccttcggata aaatccgagg ggctagaaac
      781 gttgttaaat caacggccga acttttgaat ttcatggttc gggataaaat agttcactga
      841 actattttat tttttaaggt tgtagaatga tttcaatcca cgatattcag ctacttcacc
      901 aagttggtct tcgatacgaa gcaattggtt gtatttagcg atacggtctg tacgtgaaag
      961 tgaaccagtc ttgatttgtc ctgcgttagt tgcaactgcg atatcagcga ttgttgaatc
     1021 ttcagtttca cctgaacggt gtgatacaac agcagtgtaa ccagcttctt tagccatttc
     1081 gatagcttca aaagtttcag taagagtacc gatttggtta actttgataa ggattgagtt
     1141 agcagcacct tcttggatac cacgtgcaag gtagtcagtg tttgttacga agaagtcgtc
     1201 accaacaagt tgtactttct taccaagacg ttcagtaaga gctttccaac catcccagtc
     1261 gttttcatcc ataccatctt caatagtgat gattgggtat ttgttaacca attcttcaag
     1321 gtagtcgatt tgttctgcag atgtacgaac agcagcacct tcaccttcaa atttagtgta
     1381 gtcgtaaact ttacgttctt tatcgtagaa ttctgatgaa gcacagtcaa atccgataaa
     1441 tacgtcttta cctggtacat atccagcagc ttcaatcgca gcaaggatag tttcaacacc
     1501 atcttcagtt ccttcgaaac gaggagcgaa tccaccttcg tcacctacgg cagtttccaa
     1561 accacgtgat ttaaggattt tcttaagagc gtggaagatt tcagcaccgt aacgaagggc
     1621 ttctttaaat gttggcgcac caactggcaa gatcatgaac tcttggaaag caattggagc
     1681 gtcagagtga gaaccaccgt tgatgatgtt catcattgga gttggaagaa ctttagtgtt
     1741 gaatccacca agatagctgt aaagtgggat ttcaaggtag tcagcagcag cacgagctac
     1801 agcgatagac acaccgagga ttgcattcgc acccaattta cctttgttag gagtaccgtc
     1861 aagtgcgatc atagcacggt caatagcttg ttgatcacgt acatcgtagc caatgatagc
     1921 ttcagcaatg atgttgttta cgttgtcaac agctttttgt gtaccaagac caccgtaacg
     1981 agatttgtca ccgtcgcgaa gttcaactgc ttcgtgttca ccagtagaag ctcctgatgg
     2041 aaccatacca cgtccgaaag cacctgattc agtgtaaact tctacttcaa gtgttgggtt
     2101 accgcgtgag tctaggactt cgcgagcgta aacatcagta ataattgaca ttttttactc
     2161 tccttatgag ttaaattttt tacacctcta taatacctta aaacccctcc tttttcaaga
     2221 aaaaacgtta tctttgtgca acttttcctt aactttataa agtaatcgct ttcttttgtc
     2281 tgttttattc taacttttat gatatactgt tttcatgaca gatttatcaa aacaattact
     2341 tgaaaaagct catggtgggt taaaaataaa tccggatgag caaagacgct atcttggtac
     2401 ttttgaggaa agagttcttg gatatgtaga tattgacaca gcaaatagcc ctcagttaga
     2461 aaaaggcttt ttatttattt tagaaaacct tcaggaaaaa gcagagccac tatttgtgaa
     2521 gatttcacca actatcgaat ttgataagca agttttctac ttaaaagaag caaaagaaac
     2581 tgatagtcaa gccaccatag tatctgaaga gcatattact tctccttttg gcctggttat
     2641 tcatagcaat gcaccagttc aagtagaaga aaaagacctt cgacttgctt ttccaaaact
     2701 ttgggaagtt aaaaaggaag aaccagccaa aacatcctta tggaagaaat ggtttagcta
     2761 aatcttgcac atatttaata agtgcccaat attggcagcc gtgcgctcca gatagagact
     2821 ggcatttttc aaactatctt ctaaaggttc acttttctcc aaaatagaaa agacagcttg
     2881 gatattttca aatggtaggg gaggtaaatc ttcagcaaga ctaccgcaaa tagcaataac
     2941 aggaactcca acaggggttc tttttgcaac acctataggc gctttcccag caaagctttg
     3001 actatcaagt cttccttctc caacaacaac caagtcagca tctgaaactt tcttatcaaa
     3061 gttgattaag tccaagcagg tatcaattcc agacacgata cttgcctgag caaaggcaca
     3121 caaaccacca gcaaggcctc cacctgctcc tgctccttta atttctaatg ttgcaggtga
     3181 gaatttttca taaaaatctt ggatcgcctg atctactact gcaaacatag tcggatgtag
     3241 acctttttga ttgccaaaag tgtaagtcgc accttgatga ccacataagg gactcacgac
     3301 atctgctaaa atatgaattt gaacaccttc aggaatttta tagcgatttt ctgttgaaac
     3361 agaagctaag tttaataagg attgaccgga agcaggcaag acatttccat ccctatcata
     3421 aaattgataa cctaaaccag cagcaatccc cagtcctcca tcattactgg ccgtgccacc
     3481 aacaccgata taaatatctt taatcccttt agaaatgaga tggagaatca actctccaat
     3541 accacaagtt tggatttgaa gtggatttcg tttctctagc ggaatttttc caagaccaac
     3601 caagtcagct acttcaaata gtgccagttc ccctttttga aaatagcgca tggcttcttt
     3661 ttgtccaaaa gggtctgtca cttggatcca tttttctttt aggtcaagag aatgtcggat
     3721 agcatctaca gtaccttctc cccccatcac caacagggca gaggagacat tctacatctg
     3781 ctatcgattg ttggaagcct ctttttattg cttcagctac ctgttgagct gtcaagcttt
     3841 ccttaaacga atccggtgca attacaatct tcatattttc cctcattcta aacagtcaat
     3901 caaaggaaga acttctaaaa aatccctctt gtcaacatga tgtggtattt cttttttgag
     3961 catttctttg gaacaaaagg cgattcctaa ctccgccgac ttcaacatta atagattatt
     4021 gaccccatca ccgattgcca ccgttctttc tttagaaagt tttagtttct ttctccattt
     4081 ttccagagtt tcttttttga cctggggact tataatttgt ccaactaatt ttcctgttaa
     4141 aagaccttct ttgacttcaa gctggttggc agtgaaatag gcaataccaa gggattttgc
     4201 taatctctcc aactattggt gtaaatccac caggcaccag accaactagg atgccattct
     4261 tttggagaat agagatgaac tctgggacat ttagcgatag atgaattgag ttgaagacgt
     4321 tatcaaagac caaaatagga agaccttcca acaaggacac tctttttctt aaactgcttt
     4381 caaagaccaa ctctcctcgc attgctcgac ttgtaatctg cgaaatttcc gcctcatgac
     4441 ctgcctctct ccctaaaaga tcaatcactt cttctaggat taaggttcca tctacatcca
     4501 aaacacacaa gccttttact tgagacatca gttctcctct ctaaacagcc taaaaatcgt
     4561 atgaagtcat catacgattt tatctattaa ttaactaaac tatggtacaa gtcaaggtat
     4621 gacttgcagg ctgtatccca tgagaagtca ctctccatag cttgtttttg taggtttctc
     4681 caaatgtctg gatggtttct atacaagtcc aatgctgttt ggaaagtcca atttaaccaa
     4741 taaggagata gattgtcaaa gctaaagcca gtaccgcttc cttcgattgg attgaaagcg
     4801 cgaactgtat ctcgcaagcc tccaacttca tggaccaatg gcaaggttcc ataacgcata
     4861 gccatcattt gagacaagcc acacggttca aaacgacttg gcatgaggaa gaggtcacaa
     4921 gcagcgtaga tttcctgagc aagtttgaca tcaaaagtga tatttgttga tagcttgtct
     4981 gggtaaatct gagcaaacca tgagaaagct ccttcaaagg ctggatcgcc agttcccaaa
     5041 agaacaatct gaacatcttc ttgcaagata tggtgaagac tttcgaccac cacatcaaaa
     5101 cctttttgac gtgtcaaacg agaaacaatt cccaccagtg gaacgtctgc tctaacaggc
     5161 aagccaactc tttcttgcaa ttttgcctta tttttggctt tcccagacaa atcttcctga
     5221 ttgaaatgat agtctaaaag agcatccgtc tgaggattat aaagatcagc atcaatccca
     5281 ttcacgatac cagatacttt accagactcc attttaagaa tctgatccaa attacatcca
     5341 aactgactag tcataatttc atgagcatag ctaggtgaaa cggttgaaac acggttcgca
     5401 tagagaatac ctgccttcat ccagttcaga cagttgttcc atcgaagggt gccatcagcg
     5461 taacgttcaa ggccaactcc aaacaaatca cccaacattc cttctgaaaa ttgtccttgg
     5521 aattctaaat tatgaatggt taaaactgtt tcaatgtcct cataggcttg aatccaacgg
     5581 tatttttcct tcaacaagaa aggaatcata gctgtatggt agtcatgaac atggagaaga
     5641 tcaggaataa agtcaatcct ttccatagcc tcaatggcag ccagttggaa aaaggcaaag
     5701 cgttctccgt catcaaaatc accgtaaaca tgaccacgga agaaataata ttgattgtca
     5761 ataaagtaga aggttacacc atttaatact gttttcttaa ttccacaata ctgtctgcgc
     5821 caaccaacgc tcacctcaaa atgaagcaca tcttcaatct gatttccaaa tttagcctct
     5881 accatatcat agtagggtaa aatcactgca acttcgtgcc cagcttttac cagtgatttt
     5941 ggaagagcgc caatgacgtc tcccaaacca cctgtttttg aaaagggtgc accctctgct
     6001 gctacaaata aaattttcat gaatgaatat cctctgttac tttagcacct ttcttaacca
     6061 caactggatg ttctgcagtt cctcgaatca caacaccagg ctcaacttca acccctttgt
     6121 ccaagatagc atattcgacc tgagcccctt ctccaataac aacacgaggg aagagcaggc
     6181 tatctttaac caagctatcc ttatggacat gaatattacg tgatagaaca gaattagcta
     6241 cttgaccttc aataatacta ccagaggcaa actgagaagt gcttacctta gatgtattag
     6301 catagtaagt tggctcttcg tttttgacct ttgtataaat cttttggttt ggtgagaaaa
     6361 gagaatagaa tttttgtgat tcaagcatat cgatattcgc ttgataataa gatttaacag
     6421 agtgaatatt ggctagatag cccgtgtact cgtaggcgaa agctccctct tttacagcca
     6481 aatcccgtaa aacatagcgc aatttctttg gatgttcttt tttagcttct tcttccaagt
     6541 gttcaatcaa ccaaggtgta tcaacgacaa agatatctgt agacatattg aacgtttcag
     6601 ctgttgactt gctatcaaag agtttatgag aaagaacatg gtctgtttca tctacatcca
     6661 agattgcatt tacttctgaa atatctttct tagctagttt tttataaact acagtgatag
     6721 gctcttttgt tgtactatgt aggtggaaaa cttggttcaa atcaatgtta ataagaacat
     6781 cgcagttgag ggcaaccgtt tggtttgagc cagaacgttt caaataagta agaagctgtt
     6841 ggtagtattc ttttccaact gtactacttt ctacacgggt attgtaaatt cctagatagt
     6901 aatgactaag aagggttgat aaaccccact cgcgtcctga acgaatatgg tcaaatactg
     6961 agctgatatt atcctgctgg aaaataccaa agacactacg aacacctgca ttagcaaggc
     7021 ttgaaagtgg gaagtcaatc aaacgatatt tcccaccaaa tggcaaactt gctactggac
     7081 ggtggtccgt caatgtcgac atattgtgaa aaccaactgt atttcctaaa atggcagaat
     7141 atttatcaat cttcatctgt tgttaccccc actacttcat tatatcctac aacttgtact
     7201 tcatctgttc catcaatttc gacaccgtca gaaataatcg caccttcacc aataatggca
     7261 cgtttaatct tagctccttg accaatgata gctccactca tgataactga atcaaggact
     7321 tccgctcctt cgcgaacttg cgcgcctgtt gaaaggatag aatgtttaac agttccatca
     7381 acgaaacatc cgtctacaac taatgagtct tctacatgag catttgcccc gaggaagttt
     7441 ggtggtgaaa tcaagtttct tgagtaaatc ttccattgac ggttacgact atccaaggca
     7501 ttttctggag aaatatactc catgttcgct tcccaaagtg actcaatagt accaacatct
     7561 ttccaataac cactaaattc gtaagcataa acactttcac ctgactcaag gtaatttgga
     7621 atgacatttt taccaaagtc tgacatgcca accttgctct tttcagcagc gactaacata
     7681 ttacgaaggc gttgccaatc aaaaatgtag attcccatag aagcttttgt agatttaggt
     7741 tgagctggct tttcttcaaa ttcaacaata cgattgttag catctgtgtt catgatacca
     7801 aaacggcttg cttctttaag agggacgtct aaaactgcta ctgtcaagct ggcattatta
     7861 tccttatgag actggagcat atcatcatag tccattttgt agatgtgatc cccagacaaa
     7921 atcaagacat actcaggatt gacactgtcg atatagtcga tattttggta aatagcgtga
     7981 ctagtcccct caaaccaacg atttccttca cttgcagaat aaggttgaag aatagagaca
     8041 cctgaattaa taccgtctag tccccagctt gaaccattcc caatatggtt gttgagagca
     8101 agtggttgat actgtgtaac gaccccaaca ttatgaatcc ctgagttggc acagtttgat
     8161 agggcaaagt caatgatacg gtagcgccca ccaaattgca cagctggttt tgcgatgctt
     8221 tgagtgagtt taccgagacg agttccttgc ccaccagcaa gaatcaaagc taacatttca
     8281 tttttcattt tctactcctt tttggttttt atttgtgacg gttttagtag atttcaagcg
     8341 acgtttgatt ttccatacac ttgctcccat agccggtaga gtaaaggtta aggtctgctc
     8401 ataatctttc catagtcctt cttgcgtttg aacagtttga ttatgttctt tccaaacgcc
     8461 tccccactct tccaactcag tattccatac ttcttcgtaa attcctgcaa cgggtagtcc
     8521 gattgtaaaa tctttccgct caacaggtac catgttaaag atacagacta acatttctcc
     8581 ctttttaccc ttacgaataa aggaaagaac actctggtct cgattatccg catcaatgat
     8641 ttcaatacca tcatagctgg tatcgatttc ccacagacag cgatgatctt tgtaaaactg
     8701 gtttagctga gaagtgaaat acttcatctt agcattcatt gggtcttcta tgttagacca
     8761 ttccaactgt tcttcagatt tccattctag gaattgaccg tattcgctac ccatgaagag
     8821 caatttctta ccagggtgac aaatttggta cgtatagaga ttgcgcaagc ctgcaaattg
     8881 attgtaacga tctccccaca tcttatgcat catactcttc ttgccatgaa ccacttcatc
     8941 gtgcgagaat ggcaagagat aattctcctt gaaaacatac ataaagctga aagtcaccag
     9001 gttaaagtca tatttacgat aaatcggatc ttcttcgtag aaacggagga tatcattcat
     9061 ccagcccatg ttccatttgt agtcaaatcc tagaccacca atctctttca ttcccgtaat
     9121 cttggttgca gacgaacttt cttctgcaat catcatcaca tctggatatt ctaacttaat
     9181 aacttcattc aagcgttgaa ggaaataata accttcatag ttgagatttc cgccatcttt
     9241 attaggtgtc catggagcat catcatagtc caaatagagc atgttgctaa cagcatccac
     9301 acgaatacca tccaaatgat agatatcaat ccaatgctta atgcaagaaa ttaagaagga
     9361 ctggacttca ttttttccaa ggtcaaaatt aagggcaccc caaccatggt tatgagcctt
     9421 attatggtct tggtattcaa aagtcggtgt cccatcataa taggctaagg catcatcatt
     9481 gatggtaaag tgacctggta cccagtccac aataacccca atattatggg tatgacactc
     9541 ctcgacaaaa tcttgaaact cctctggtct accataggca tgctctaaag cgaagtaacc
     9601 cataagctgg tacccccaac tcaaacctag tgggtgggac atcaagggca taaactcaat
     9661 atgagtatag ttcatctcaa ctaggtaagg aatgagttca tctttcaatt gggcaaaact
     9721 ataaggactg ccatcagaat ttcttttcca tgatccagcg tgaacttcat aaatattgac
     9781 aggacgctct tcaaagcccc aacgttttct tcgtgccagc caaagtccat ccttccattt
     9841 cttctcagga agctctgtta agattgcccc tgttcctgga cgagcctcat acctgacagc
     9901 aaaagggtca atcttcatca gttgatgacc attttgacgt gtgacatgat atttgtaaat
     9961 atgcccttct tgagccatat tggtaaagac ttcccagacc ccaaaatcat ttcttaccat
    10021 tggaatctga ttttcaatcc agttggtaaa atcaccaacc aagtgaacag cctgagcatt
    10081 aggtgcccaa acacggaagg tatagccatg ctctccattt agttcttccc tatgtgctcc
    10141 tagataatgt tggagataaa aattttcacc catcataaag gtttttaatg cttctctatt
    10201 atccatatac tccctttctc ctgtaagcgt tttctatgtt tttattatac taccttttta
    10261 gagaagattc aagtaaatta ctatacttct tta
//
LOCUS       DAVLDI010000072         9938 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLDI010000072 DAVLDI010000000
VERSION     DAVLDI010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.073"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            12..454
                     /locus_tag="VXD01_001995"
                     /pseudo
     CDS             12..454
                     /locus_tag="VXD01_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826702.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            492..794
                     /locus_tag="VXD01_001996"
     CDS             492..794
                     /locus_tag="VXD01_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0602332.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            802..1604
                     /locus_tag="VXD01_001997"
     CDS             join(802..1252,1252..1604)
                     /locus_tag="VXD01_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0602333.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDFLMATLQYVREYRTYEEIAADFGIHESNLIRRSRWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKELANYSGKKKCHAMKAQAIVTSQGRFVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            1653..2117
                     /locus_tag="VXD01_001998"
     CDS             1653..2117
                     /locus_tag="VXD01_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV0602334.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2275..2700
                     /gene="lacA"
                     /locus_tag="VXD01_001999"
     CDS             2275..2700
                     /gene="lacA"
                     /locus_tag="VXD01_001999"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV0602335.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2731..3246
                     /gene="lacB"
                     /locus_tag="VXD01_002000"
     CDS             2731..3246
                     /gene="lacB"
                     /locus_tag="VXD01_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV0602336.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3257..4186
                     /locus_tag="VXD01_002001"
     CDS             3257..4186
                     /locus_tag="VXD01_002001"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV0602337.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            4188..5168
                     /gene="lacD"
                     /locus_tag="VXD01_002002"
     CDS             4188..5168
                     /gene="lacD"
                     /locus_tag="VXD01_002002"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV0602338.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5402..6238
                     /locus_tag="VXD01_002003"
     CDS             5402..6238
                     /locus_tag="VXD01_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV0602339.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            6274..6591
                     /locus_tag="VXD01_002004"
     CDS             6274..6591
                     /locus_tag="VXD01_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0602340.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6593..8287
                     /locus_tag="VXD01_002005"
     CDS             6593..8287
                     /locus_tag="VXD01_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV0602341.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTVKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAKYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            8502..9908
                     /gene="lacG"
                     /locus_tag="VXD01_002006"
     CDS             8502..9908
                     /gene="lacG"
                     /locus_tag="VXD01_002006"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV0602342.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
BASE COUNT         3192 a         1727 c         2060 g         2959 t
ORIGIN      
        1 acaaaaacct tgtgttttgc ttagaagcgg ataatcaaga ataacttttt gatcaggtag
       61 caagcttgtt ggaagaacga gaaattgtca ctccaactta tcgtgaagcc ttgatcacgc
      121 gtgaaaagtc atttccaact ggtttagata tgaaattttt aggaaaggac ttgcaaatgt
      181 aatgattcct cacacagata ttgttcataa tctagctgag aaagtggtgg ttgttcgatt
      241 agagaaatcg gtgactttcc ataatatgat tgcgccaggt aaggaagtag aagtatcctt
      301 gctcttcttt atcatcaata attcaagttc aagtcaaacg aacattcttg ctcagttgat
      361 ggactttttc acaggaaatg gacatcttga agacctatca aaaatttccg aaccagaaaa
      421 actttatgct tatatagatg aagcaatcgc ttaatcttgt ctattaaaaa ataaaatcgg
      481 aggaagtcta tatgattaaa attcttgctg cctgcggtgc aggtgttaac tcaagtcacc
      541 aaattaaaag tgctctagaa gaagaacttt caaaccgtgg ttatgatgtt cactgtgatg
      601 cagtcatggt gaaagatgta aacgaagacc ttatgaaagg ttacgatatc tttacaccaa
      661 tcgctgcaac agaccttggt tttgaaccag gtatcccagt tatcgaagct gggccaatct
      721 tattctgtat cccagcaatg agcgttccag tatttgacaa tattagactt cctgcgaaac
      781 aaaatatggt atagtagttc catgaattat gaagcaagta aacaactaac tgatgcacga
      841 tttaagcgtc ttgttggtgt tcaacgcacg acttttgaag agatattagc tgtattaaaa
      901 acagcttatc aacttaaaca cgcaaaaggt ggacgaaaac ctaaattaag cctagaagac
      961 tttcttatgg ccactcttca atatgtgcga gaatatcgaa cttatgaaga aattgcggct
     1021 gattttggta tccacgaaag caacttaatc cgtcggagcc gatgggttga agtaactctt
     1081 gttcaaagtg gtgttacgat ttcaagaact cctctcagtt ctgaggacac ggtaatgatt
     1141 gatgcgacgg aagtacaaat caatcgccct aaaaaagaat tagcgaatta ttctggtaaa
     1201 aagaaatgcc acgctatgaa ggctcaagcg attgtcacaa gtcaagggag attgtttctt
     1261 tggatatcac tgtgaactat tgtcatgata tgaagttgtt caaaatgagt cgcagaaata
     1321 tcggacaagc tggtaaaatc ttggctgaca gtggttatca agggctcatg aagatatatc
     1381 ctcaagcaca aactccacgt aaatccagca aactcaagcc gctaacagct gaagataaag
     1441 cctgtaacca tgcgctatcc aaggagagaa gcaaggttga gaacatcttt gccaaagtaa
     1501 aaacgtttaa aatgttttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa
     1561 tgaatttgag tgctggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta
     1621 ataaagaaac tagcaaggtc agaccttact ttattggtgg acatccagga tttaattgtc
     1681 ttctacttga tgatgaagtc tatgaagatt attatctaga gtttgagaaa gaagagattt
     1741 gctctgttcc acgtcctttc ccagaaacag gtatgttgga tttccaagat agaagtccat
     1801 ggctagaggg acaaaaagaa atagatctta gttatgatct tttcagcaca gatgcagtga
     1861 ctttggatga attgcaatct cgaacaattg cccttcgttc tcttaaacat gataagggat
     1921 tgaaagtgca ttttgcagaa tttccaaacc tcatcatctg gtcaactttg aacaagggac
     1981 ctttcattac ctttgaacca tggtctggct tgtcaacatt ccttgaagaa ggagatcatt
     2041 tagaagataa gaagaatgtt tgtctcttag aagccaatca ggttgaagaa ttagggtttg
     2101 agatagaagt tttataaaaa aagtaaaaaa taaataacaa aaacaaacac aaactgttga
     2161 cttcttcaaa caatagtagt atattatgtt tgtgaggact aattgactgt tttttaaaga
     2221 cagccaatac actgctggaa tccagcatag aaaaaataaa aaggagtata caatatgtct
     2281 attgttatcg gcgcagatgc tgcaggtttg agattgaaag aagttgtgaa agacttctta
     2341 gaaaaagaaa acttccacct tgtggatgtt acagctgaag gtcaagactt tgttgatgtg
     2401 actctcgctg ttgctgcaga agtaaacaaa gaagaacaaa accttggtat cgtgattgat
     2461 gcttatggag ctggtccatt tatggttgca actaagatca aaggaatggt tgctgcagaa
     2521 gtatctgacg aacgttcagc ttatatgact cgtggccaca acaactcacg tatgatcact
     2581 atgggtgcac aacttgttgg tgatgaattg gctaaaaaca tcgctaaagg atttgttaac
     2641 ggtaaatacg atggtggacg tcatcaaatc cgggtcgaca tgttgaacaa aatgggctaa
     2701 ttagattaca gtaagaaagg taagttaaaa atgagaattg caattggatg cgaccacatc
     2761 gtaacagatg aaaaaatggc ggtttcagaa tttttgaaat caaaaggata tgaagtcatt
     2821 gactttggta catatgacca tacacggact cactacccaa tctttggtaa aaaagtaggg
     2881 gaagctgtaa ctagcggcca agctgatctt ggggtatgta tctgtggtac tggtgttggt
     2941 atcaacaacg ctgtaaataa agttccaggt gttcgttctg ccttggttcg tgatatgaca
     3001 acagcccttt atgctaaaga acaattgaac gctaacgtta tcggctttgg tggtaagatt
     3061 actggtgaat tgcttatgtg tgatatcatc gaagctttca ttcatgctga atacaaacca
     3121 tctgaagaaa acaagaaatt gattgcgaaa attgaacacc ttgaaagtca caatgctcaa
     3181 caaacagacg caaacttctt tacagaattc cttgaaaaat gggatcgcgg agaataccac
     3241 gactaagagg tgacctatga ttttaacagt cacaatgaac ccatccattg atatttccta
     3301 tcccttggat gagttgaaga ttgatactgt caatcgtgtg gtggatgtaa ccaaaacggc
     3361 tggtggtaag ggactcaatg ttacccgagt actttcagaa tttggcgatt ctgttcttgc
     3421 tactggttta gtgggtggca aacttggtga gtttttggtt gaacatatcg ataatcaagt
     3481 aaagaaagat ttcttctcaa ttcagggaga aactcgtaac tgtatcgcta ttctccacgg
     3541 agacaaccaa acagaagttc ttgaaaaagg tcctgaagta ttggaacagg aaggtcaaga
     3601 ctttttggaa catttcaaaa aactcttgga gtcagttgaa gtagtggcca tctcaggtag
     3661 tctgccagct ggccttccag ttgattacta tgcgagcttg gtagaacttg ctaatcaagc
     3721 tggcaagcct gtagtcttgg actgctcagg tgcagcactt caggctgttc ttgaatcacc
     3781 ccataaacca acagtcatca aaccaaataa tgaagaattg tctcagcttc ttggaagaga
     3841 agtttctgag gatttggatg aattaaaaga agtacttcaa gaacctttgt ttgcagggat
     3901 tgaatggatt atcgtttcac ttggtgccaa cggtactttt gccaaacatg gtgacacttt
     3961 ctacaaggta gatattccta gaattcaggt ggtaaatcct gttggatctg gagactctac
     4021 tgtggcagga atttcttcag gacttcttca caaagaatcg gatgcagaat tactcatcaa
     4081 ggcaaatgtc cttggtatgc tcaatgctca agaaaaaatg actggtcatg tcaacatggc
     4141 caactatcaa gctctatatg atcaattaat agtaaaagag gtataaaatg gctttaacag
     4201 aacaaaaacg tgtacgctta gaaaaacttt ctgatgaaaa tggtatcatc tcagctcttg
     4261 catttgacca acgtggtgct ttgaaacgcc tcatggctca acaccaaaca gaagaaccaa
     4321 ctgtggccca aatggaagaa cttaaagtct tggtagcaga tgaattgact aaatacgctt
     4381 catctatgct tcttgaccct gagtatggac ttccagcaac taaagctctt gatgaaaaag
     4441 ctggtcttct ccttgcttat gaaaaaacag gttatgacac aacaagcaca aaacgcttgc
     4501 cagactgctt ggatgtttgg tctgcaaaac gtattaaaga agaaggtgca gatgcagtta
     4561 aattcttgct ttactatgat gtagatagct cagacgaact caatcaagaa aaacaagcct
     4621 acatcgaacg catcggttct gagtgtgtgg ctgaagatat cccattcttc cttgaaatcc
     4681 ttgcttacga tgaaaaaatt gcggatgcag gttctgtaga atacgcgaaa gtaaaaccac
     4741 acaaagttat cggcgctatg aaagtctttt cagacccacg ctttaacatt gatgtcttga
     4801 aagttgaagt tcctgttaac attaaatatg ttgaaggctt cgctgaaggt gaagtagttt
     4861 atacacgtga agaagcagca gccttcttca aagcgcaaga tgaagcaacg aacttgccat
     4921 acatctactt gagtgctggt gtatcagcta aactcttcca agatactctt gtatttgctc
     4981 atgaatcagg tgcaaacttt aacggagttc tttgtggccg tgctacatgg gcagggtcag
     5041 ttgaagctta catcaaagat ggtgaagcag cagctcgcga atggcttcgc acaactggat
     5101 ttgaaaacat tgatgagctc aataaagttc ttcaaacaac agcgacttca tggaaagaac
     5161 gtgtgtaaga aagtcctcct agtttaggaa catgaatcta aaaaaattta aaaaaagttg
     5221 tatgtaaagg tttacaaaac aaccgacttg tgctatactt aaatcacaag ttaatacaag
     5281 gtgagtgtta ctaagtaata ttaggcatga tcacaggtga attagaaatc agctgatttt
     5341 ctagttcatt tgtggtcatt ttttgtactc atataccttt aagatataaa aggaggttga
     5401 catgtatcga attctaaatc caatgaatca caatgtctcg cttgttagaa atgataaggg
     5461 agaagaggtg attataattg gtaaggggat tgcattcgga aaaaggaagg gggatttgat
     5521 tgctgaaaat caggttgaga aaatctttcg gatgaagacc gaagagtcca gagaaaactt
     5581 tatggctctt ctcaaagatg ttccgcttga ttttatcaca gtgacctatg aaatcattga
     5641 taagctatca aagaaatatc attatccgat tcaagagtat ctctatgtaa ccttgacaga
     5701 tcatatttac tgttcttatc aagctctaac tcaaggaagg tacaaggata gtaatctgcc
     5761 ggatatttcc gctaagtatc ctgtcgcttt tcaaatcgca aatgaagctt ttgaaattta
     5821 ccgtcagaag ctagcagatc attttcctga ggacgagatt attcggattg cttatcattt
     5881 catcaatgcc gaaggtgaaa atgaagtgga acttgtggag tcgattgata agaggaaaga
     5941 aattctcagg aatgttgaag aagttttaac ggactatgca attcaacgaa ctaaaaagaa
     6001 taaccatttc tatgatcgct ttatgatcca tttgaattat ttcttggatt atttagacag
     6061 atctagagat gataaccaat cacttctgga tatggaagat catattaaac aatcctatcc
     6121 aaaagccttc gagattggtt ccaagatcta tgatgtgatt acgcaacata cgggtcttga
     6181 tttgtataaa agtgaacgag tttatctagt tctacatatc caacgtttat tgtcataaaa
     6241 atttatttaa aactatataa ggagaattct atcatgaata gagaagaagt aacattgtta
     6301 ggttttgaaa tcgtagccta tgctggcgat gctcgttcaa aactattgga agccttgaag
     6361 gctgctgaag ctggtgattt tgaaaaagcg gacgctctgg tagaggaagc tggtagctgt
     6421 attgcagagg ctcaccacgc gcaaacaagt ctattgacta aggaagcttc tggtgaggac
     6481 ttagcgtata gtgtgaccat gatgcatggt caagatcact tgatgacaac tatcttgtta
     6541 aaagacctaa tgcaccattt aattgaactt tacaagagag gagttaaata aaatggataa
     6601 gttaataatt tttattgaga aaggaaagcc tttctttgag aaattatcga gaaatatata
     6661 cttaagagcg ataaaagatg gttttatttc cagtatgcca gcagtattat tctcaagtat
     6721 ttttatacta atagctgctg tgcccaatat ttttgggttt aaatggtctg atgaacagtt
     6781 agcttttatt ttgaaacctt acaactactc aatgggaatt ttagctctct tagtagctgg
     6841 gacaactgca aaatcgttaa cagattcagt taatacacgt agtatggaga aaaccaacca
     6901 aatcaactac atgtcaactt ttttagcagc tgttgttgga ttgttaatac tggcagctga
     6961 tccaattgaa ggtggatttg ctaatggtct tttaggtact agaggattac ttactgcatt
     7021 tttggcagct tttattacag taaatatcta taaagtatgt attaaaaata atgtaaccat
     7081 tagacttcct gaagaggttc caccaaatat tgcacaagtt tttaaagatg ttattccgtt
     7141 tgccttatct gttctttcaa tatatggatt ggatttaatt gttagaaata tttttggtac
     7201 aaatgtagca gaatctgttg gtaaaatatt agcccctcta ttttcagcta ctgatggtta
     7261 tatcggttta gctattgtat ttggtgctta tgctttcttt tggtttgttg gaattcatgg
     7321 gccatctgtt gtagaacctt taattgtagc tatcagttat gcaaatatag aagctaatgt
     7381 tcagcttgtg caagctggta tgcacgcaga taaaatttta aatccagtta ctcaaacttt
     7441 tgttgtaaca atgggtggta ctggtgcaac actagtagtt ccatttatgt ttatgtggtt
     7501 atgtaaatca aaaagaaata gaattgtcgg acgtgcgtct gtagttccta ctttctttgg
     7561 cgtaaatgaa ccaatcctat ttggtgctcc aattgtttta aatcctatct tctttattcc
     7621 gtttgttact gctcctatta tcaatgtttg gattatgaaa ttttttgtag atgttctaca
     7681 aatgaatagt ttcagtatta ttttaccttg gacaacacct gctccaattg gtattgttat
     7741 gggaacggcg ctggctccat tgtcattcgt cttggctata actttaatca ttatcgacac
     7801 tttaatctat tatccatttg ttaaagttta tgaccatcaa attttagaag aagaacggaa
     7861 aggaaactct tcatctgaat tgaaagaaaa agttgctgca aacttcaaca ctgtaaaagc
     7921 ggatgctatt cttgaaaaag caggtgtcga tgcagcacaa aataccatca ctgaagaaac
     7981 aaatgtcctc gttctctgtg ctggtggagg tacaagtgga ctccttgcaa atgctttgaa
     8041 taaggcagca gcaaaataca atgtccctgt gaaagcagca gcaggtggct atggtgctca
     8101 ccgtgaaatg ttgccagagt ttgatcttgt tatccttgcc cctcaagttg cttcaaactt
     8161 tgaagatatg aaggcagaaa cagataagct cggtattaaa cttgctaaga cagaaggcgc
     8221 tcaatacatc aaattaactc gtgatggaaa aggtgcccta gcattcgtac aagagcaatt
     8281 cgattaaggc taggaactgt gaaacagtct cccatcgtta cggaaatcgc tatggcgaat
     8341 ttcctaatcg ccttattaat tcgtcggtaa aaagatatcg tttttacctc ctcatgtcac
     8401 aattcagtga tttggcacaa gaagtgagat ggagaagcat ggctcactga ctcctctcct
     8461 ctcactttta ctttatttaa atcaagaaat aggtgaaaaa aatgacaaaa acacttccaa
     8521 aagactttat tttcggtggc gcaacagctg cttatcaagc agaaggtgct acacatactg
     8581 atggaaaagg accagttgct tgggataaat atcttgagga taactactgg tacactgccg
     8641 aaccagctag tgatttttac aatcgatatc cagttgacct caagctagca gaagagtatg
     8701 gtgtcaatgg tattcgaatt tctattgctt ggtcacgtat tttcccgact ggttacggcc
     8761 aagtaaatgc taaaggtgtt gagttttatc ataatttatt tgcagagtgt cacaaacgtc
     8821 atgttgagcc ctttgtaact cttcatcact ttgacactcc agaagctctc cactcaaatg
     8881 gagacttctt aaaccgtgaa aatatcgaac attttgtaga ctacgctgcc ttctgttttg
     8941 aagaatttcc agaagtaaac tattggacaa cctttaatga aattggacca atcggtgatg
     9001 gtcaatattt ggttgggaaa ttccctccag gtatccagta cgaccttgcc aaagtctttc
     9061 aatcacacca caatatgatg gtgtctcatg cacgcgcggt aaaattgtac aaagagaaag
     9121 gctataaagg ggaaattggt gttgttcacg ccctgcctac taaatatcct ctagatcctg
     9181 aaaatccagc agatgttcgt gcagctgagt tggaagatat catccacaat aaattcatct
     9241 tagacgcaac ttatctaggt cgctattcag ctgaaaccat ggaaggtgtc aaccatatct
     9301 tatcagtcaa tggtggtagt ttggatcttc gtgaagaaga ttttacagca ttagaagctg
     9361 caaaagactt gaatgatttc ctaggaatca actactatat gagtgactgg atggaagcct
     9421 ttgatggaga aactgaaatt atccataatg gtaaaggtga aaaaggaagc tctaaatacc
     9481 aaatcaaagg tattggtcgt cgtgtagctc ctgactatgt accacgcacg gattgggatt
     9541 ggattatcta ccctcaaggt ttgtatgacc aaatcatgcg tgtgaagaaa gattatccta
     9601 actacaagaa gatttacatc actgaaaatg gtctcggcta taaagatgag ttcgttgata
     9661 acactgttta cgatgatggt cgtattgatt acgtgaaaca acacttggag atcttgtctg
     9721 atgcgattgc agatggagct aatgtaaaag gttacttcat ttggtcatta atggatgtct
     9781 tctcatggtc aaacggttat gagaaacgtt atggtctctt ctacgtagat tttgaaactc
     9841 aagaacgtta tcctaagaaa tcagctcact ggtacaagaa agtagcggaa actcagatta
     9901 tagactagta gaattagtca ttagatatag aattttag
//
LOCUS       DAVLDI010000073         9488 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLDI010000073 DAVLDI010000000
VERSION     DAVLDI010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9488
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.074"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            236..1414
                     /locus_tag="VXD01_002007"
     CDS             236..1414
                     /locus_tag="VXD01_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV0602343.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(1642..2088)
                     /locus_tag="VXD01_002008"
     CDS             complement(1642..2088)
                     /locus_tag="VXD01_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0602344.1"
                     /translation="MTIRFEEKVSIENAQLVCQWSNSLGKVFQEQWMGPRIPFPLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLDSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRVQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            2158..2817
                     /locus_tag="VXD01_002009"
     CDS             2158..2817
                     /locus_tag="VXD01_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV0602345.1"
                     /translation="MIDIYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLH
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLFYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASTTGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(2789..3565)
                     /locus_tag="VXD01_002010"
     CDS             complement(2789..3565)
                     /locus_tag="VXD01_002010"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV0602346.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(3558..4781)
                     /gene="trpB"
                     /locus_tag="VXD01_002011"
     CDS             complement(3558..4781)
                     /gene="trpB"
                     /locus_tag="VXD01_002011"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV0602347.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(4759..5358)
                     /locus_tag="VXD01_002012"
     CDS             complement(4759..5358)
                     /locus_tag="VXD01_002012"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV0602348.1"
                     /translation="MTKVKICGLSTEEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPSDVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(5345..6112)
                     /gene="trpC"
                     /locus_tag="VXD01_002013"
     CDS             complement(5345..6112)
                     /gene="trpC"
                     /locus_tag="VXD01_002013"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV0602349.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALAEERLKELYDYATVLGLEVLV
                     ETHNLAELEVAHRLGAQIIGVNNRNLTTFEVDLQTSVDLAKHFKDDCLYISESAIFTR
                     QDAERLAPYFNGILVGTALMQAENVVQRIKELQIDKG"
     gene            complement(6109..7113)
                     /gene="trpD"
                     /locus_tag="VXD01_002014"
     CDS             complement(6109..7113)
                     /gene="trpD"
                     /locus_tag="VXD01_002014"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV0602350.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(7124..7690)
                     /locus_tag="VXD01_002015"
     CDS             complement(7124..7690)
                     /locus_tag="VXD01_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV0602351.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(7687..9048)
                     /gene="trpE"
                     /locus_tag="VXD01_002016"
     CDS             complement(7687..9048)
                     /gene="trpE"
                     /locus_tag="VXD01_002016"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV0602352.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYIVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEVMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
BASE COUNT         2618 a         2228 c         1789 g         2853 t
ORIGIN      
        1 tatctttatt ttttgacgtc aagttgttat ttgattatct tttgttattt atattttaca
       61 actataagaa agccttgtca aggatttgtg taaacatttg attatttttt attatcaata
      121 tataataaaa agagaccagt aagtaatgaa aagcttaaaa agattaacat ctacatttat
      181 ccatagcaaa aaatcatagg attttaagaa tctgacaact aggaagaaaa ctaatatgac
      241 cttatccaag aaacaattac aactaagagc taaaatactg gaaacagttt acacattagg
      301 tcccatttca cgaattgaaa tcgctactaa aacaggaata acacctgcaa caactagcag
      361 tatcacaaat gatctgatta aagaaaatat tctcttagaa cttggtgaag acgaacacga
      421 tacaagcgta gggagaaaaa aaatcctgct agacattcaa gctaaacgat tttactacat
      481 tggttgtgaa ctatctgaaa aacatttcac ttttgcttta ggagataatc taggaaatat
      541 cttaaaggaa gagaaagaaa ttgttactaa acagttaatc caagaaaagg gaaatcaact
      601 cattaaccag acactaaagc aattcttaaa taactgctct gattatgaaa tagaagcaat
      661 tggaatcgcg ctacctggtc gctatttaga taattataaa ataacaacaa acaatccttt
      721 atggcaacat atcgacttag aaatgattca atcccacttt gataagcctt tgtttttctc
      781 taacaatgtt aactgtatgg ctataggtaa acgcctattt agtcgccaac agaatgaccc
      841 taattttgct tattttcatt ttgctagagg tatgcactgt tcttatatct acgacggaaa
      901 catttatggg aaaggaaatc taatgattgg agaaataggg catacagttg tttcatctga
      961 gggagaagaa tgtagctgcg gacgcaaggg atgcttacaa acttttgctg gagaatcttg
     1021 gttaatcaaa aaatcaaaaa ttctatatca tcaatctccc tattctctac ttcctagttt
     1081 agtcaaaaat gccgatgata ttgatatcca agttatttta accgcttatc aattaggtga
     1141 cactggaata atcacactta tccatcaagc cttactctat cttagtcaaa ccattttaaa
     1201 tatcagtatg atgattgact ctcaaaaaat ctacctacat agtcctttac taacaaatca
     1261 acacatcatc caaaaactat atagtgaaat gaactacaaa cccaaactgc tctataatcg
     1321 cctacctgaa gtcattattg aaccttacaa tgattttaca gccgcacact cagctattgc
     1381 actttgtttg tatcatacaa ttctacattc ttaattttct attacattta ataaataggc
     1441 taaaaagagg gagtatatca taaaaagcga ataaacctgt tttctgaaaa tcagaattct
     1501 gttttgttcg ctttctttat atttggaatt atactcctat ctcccctttt tcataatgta
     1561 taataaaatg aaataataac aggacgaatc gatcgggaca gtcaaatcga tttctaacaa
     1621 tgttttagaa gtagaggtgt actattctag tttcaatcta ctatattttc gtacaggtgc
     1681 ttcaaccatt tgaacgattt caaatccttc tttttggtaa agattctgaa ctctttgatt
     1741 tgcctcgaag acatttagag aaatactatc tatatcttca ttttcaaagg ccaaactaac
     1801 aaatttcctt aaagcttggc tatctaagcc ttgcccctgt ttctgggggt tgataaaaaa
     1861 tctcccgata tgaagattgc tgtcttctag cctgattttc tggataagtc ccacaaactc
     1921 ttgttcatca aagattgaaa agactccttc caaggcttga agggtcagtg gaaaaggaat
     1981 ccttggtccc atccattgtt cttgaaagac tttgcctaag gagttggacc actggcatac
     2041 gagctgagcg ttttctatac tcaccttttc ttcaaaacga attgtcatct tttcctcccc
     2101 atcttatcta tgtttctcca ttatactact tctcccattt tttacgaata gataagtatg
     2161 attgatattt atttttttct tgtcgggagc attctcgctt cctttcttgg tttggtcatt
     2221 gaccgttttc cagagcaatc cattatcagt tcagccagtc actgcgattc ctgtcagact
     2281 cgcttgcatc ccttagattt gattccgatt ctctcacagg tcttcaatcg ctttcgctgt
     2341 cgctactgca aagttcgcta tcctgtctgg tatgccctct ttgaactagg cttaggactc
     2401 ctctttctgt tttactcttg ggaattgctt tccttggggc aagtcgtcct aatcaccgct
     2461 ggtttgacct tgggtatcta cgactttcac catcaggaat atcccttact ggtctggatg
     2521 actttccacc taatcctaat agcttcctct ggctggaatc tggtcatggt ctccttcctc
     2581 atacttggaa ttttggctca ttttatcgat atccgcatgg gtgcagggga tttccttttt
     2641 ttagcttctt gtgctctcgt ctttagcgta acggagttac tgatcttgat tcagttcgct
     2701 tctacgacgg gtatcctggc ctttctcctg caaaagaaaa aggaaagact tcctttcgtg
     2761 cctttcctct tacttgctac ttgtttgatt atttttggta agctactgct tgtttgataa
     2821 agtcctgaat cggctctcct tggtggagag cttttactat tttcgaaccg acgataacac
     2881 catctgacac cgcattgaag cgttccagat cggcttgact agatacacca aaacctgtca
     2941 agactgggat gtcggccact tgatgaagtt gcgccaagtg cttgtccaaa tctgcacggt
     3001 aattgcctga tttccctgtc actccattga tggcaacggc atagatgaat ccctccgccc
     3061 cttcaatcaa ctctttctgg cgctcaattc ctgtggtcaa gcttactaaa ggaatcaagg
     3121 cgatatctgt atctgccaaa aatggttcta caaagttggc atgttcatga ggcaagtctg
     3181 ggataatcaa gcccttcaca gctgtatcag ccagatcttt gacaaagttc tccacaccgt
     3241 actgaaagag ggggttgaag taggtcatga tgaccagtgg aatctctgtt tcaatggttt
     3301 tcaaggtttc aactaaagcc tgggtagagg tcccgtgggc taaactgcgc aagccagctt
     3361 cttcgataac aggtccatct gcaacagggt ctgaaaaggg aatacccact tcaattgcag
     3421 agacacccaa atcttctaaa aagtgaattg tttcagcaag accgtccaaa cctttctcgt
     3481 ggtcaccagc catgatatag ggaacaaaaa ttccttttcc agctgcttta atagcattca
     3541 atttttctgt tagtgtctta ggcatgagct tctcccttct ttgctgcatc tgcttccaag
     3601 cggtctttga cttgaaccac atccttgtcc ccacgacctg ataggcagac aatcatagac
     3661 ttttctggtc caagttcttt ggccaatttc accgcaaaag cgatagcatg gctagattcc
     3721 aaggctggga taatcccttc cacacgagac aagagttgga atccttccaa ggcttcttcg
     3781 tctgtcacag ggacatagct ggcacgtttg atatcgtggt agtgagaatg ttctggacca
     3841 ataccaggat agtccaaacc tgctgagata gagaaggctt caagaatttg accatgggca
     3901 tcttggagca catccatgag agaaccgtga agaacacccg gacgaccctt ggtcaaggta
     3961 gcagcgtggt gctctgtatc cacaccaagc cctgctgctt cagttccata catagctact
     4021 gactcatctt ctacaaaggg atggaagagc ccaatagcat tagatccacc accaacacag
     4081 gctactagag catcgggcag attttgacct gtcatatcgc gatactgttg tttagcttcg
     4141 cgaccgatga cactttggaa gtcacgaacg atttctggaa atggatgagg ccccaaggca
     4201 gaaccaagga tatagtgggt atcgtcgata ttagccaccc atgaacgaag ggctgcattg
     4261 accgcatcct tgagcacgcg cgaaccatct gttacagcct cgaccttggc tcccaaaagc
     4321 tccatgcgga agacattgag ggcttggcgt ttgacatctt cctcacccat gtagatggta
     4381 cattccatgt taaagagggc cgcagcagtt gcagttgcca caccgtgctg accagcaccg
     4441 gtttctgcga taattttctt tttacccatg cgtttggcaa gccaaacttg tcctaaggca
     4501 ttgttaatct tgtgggctcc tgtatggtta aggtcttccc gtttgagata aatcttggct
     4561 ccgccaatat gctgggtcaa gttttttgcg tagtaaagag gagtttcccg ccccacatac
     4621 tggcgcaaga gttggtttaa ttcctcttgg aaacttgggt ctgcctgact ttcacgatag
     4681 gccttctcca actccaaaac tgctgtcatc aatgtttctg ggacaaaacg tccgccgaat
     4741 tttccgtaaa atccatcttt atttggttcc tgatatgcca tgctttaccc tctctataaa
     4801 tcttctaatc ttttcatgat ctttttgtcc atctgtctcc actccgctcg atacatctac
     4861 tgcataggga gtaaaatgtt gaattgcttt tactacatta tcttcattaa ggccacctgc
     4921 gataaagaag ggctgtgcta gtccagtcgt atccagttga ccccaatcaa agggctggcc
     4981 acttcctgcc acaggggcat caaagagtag ataatctgcc tgagaattgg ggacatgccc
     5041 atttccatct acctgcacag cctgaatact ggcacaaggc aaattctcaa ataaatcatc
     5101 tgccacctga ccgtgaactt gaaccaagtc caagccaact ttgtcaatcg cttccagcag
     5161 ttctacccga cttggtgaaa caaatactcc aacctttttc acatctgaag gaataagctt
     5221 tgccaactca gctgcctctt ctaaagtcac ctgtctttta ctaggtgcaa agacaaaacc
     5281 gatgtagtcg gctcctgctg aaacggctgt ttccaccgct tcttcggtcg atagtccaca
     5341 aattttaacc tttgtcaatc tgcaactcct tgattctctg gaccacattt tctgcctgca
     5401 taagagctgt ccctaccaaa attccgttaa agtatggggc tagtcgttcc gcatcctgcc
     5461 ttgtgaaaat agcagattca gaaatgtaca agcaatcatc tttgaaatgt ttagccaagt
     5521 ctacactggt ctgcaagtcg acctcaaagg tggtcaagtt gcggttattg accccgataa
     5581 tctgggcacc aagtctgtga gccacttcta gttcagctag attgtgagtt tccaccaaga
     5641 cttccagacc aagcactgtc gcgtagtcgt aaagttcctt aagacgttct tctgccaagg
     5701 ctgccacaat gagcaagatg actgtcgcac ctgcattgcg agcgcggatg atttgctttt
     5761 catcgatgat aaagtccttg ttgagcgtcg gaatctctac ctgactggaa atctcccgta
     5821 gataatccaa atgtccttta aagaaaactt catctgtcaa caccgaaatc atcactgctc
     5881 cgttttcttc ataagtctgg gcctgttgca caatatccac atcgagattg atatctccca
     5941 aactagggct agctttcttg acctcagcga ttacctgcaa gcggtcctga tgattcttca
     6001 aaaattctgc caagcgatag gtctggcgca gaggctggat ttgctccagc ttcatctgct
     6061 ccacctcacg cgccttctgc tctaagattc gtgctaaaaa ttcctgactc atttttggta
     6121 ctcctgtaac agtctgagtt tttcaagggc cttgcctcta gcaatcactt gacgggccaa
     6181 ggcaactcct tccttgatgc tatcaatctt accattagca tagaaaccaa gaccagcatt
     6241 caagactgtc gtttccaaga atggacttgc ttcgtttttc agaacgctaa gcaaaatttc
     6301 tgcattttcc tgagcattcc caccacgaat atcttccata gcatagcctt ccattcccaa
     6361 atcctctgga gtaaagcttg acaagctgat ttcgccattt tcaagaagtg caatcttggt
     6421 tgttccgttc aagccagctt catccaaccc ttctggtcca gcaaccacga tggcacgttt
     6481 gcgacccata tttttcaaaa cctgagctgt actttctagg agttctggac gactaattcc
     6541 aagaagctgt gtttctaaag ccattggatg aatcagtgga ccagtcaagt tcataatcgt
     6601 tggaattccc aattccaaac gagctggcat gatgtatttc atagctgggt gcatattttt
     6661 agcgaagaga aagacgattc cagttttatc aaagacctta cctagttcag ctggtttgag
     6721 atcaagattg attcccaagg cttcgaggac atctgcggaa ccagatttag aagaaatcga
     6781 gcggttacca tgcttggcca tgtgaatacc gccaccagcc aagacaaagg ctgcagttgt
     6841 ggaaatatta aaactgaaag acttgtcccc acctgtacca cagttatcca tggcatcatg
     6901 aatctcagtt ggaatatgct gggcatgtcc tctcatgact tgggcaatgg ctgtgcgttc
     6961 ttcaggtgtt tcccccttca tcttgagagc taagaggaga gaagcaatct gcgcttcagt
     7021 tacacgccca gttacgatac gctcaatgac atccgtcatt tccacacctg ataaattttc
     7081 aaattttgct agtttttcaa taatctcttt catcctagtt tcctcacttt acaaccttct
     7141 cgataaaatt ccgaatagaa gacaagccgt ctggcgttcc aatgctctct ggatggtact
     7201 ggaagccata aatcggtagg tttttatgtt gaatccccat gatggcttgg tcatcagtcg
     7261 aacgagctgt cacttcaaag tcttctggca tttcctcaat caaaatactg tgataacgca
     7321 tgaccgcacg tccatcctca ataccttgat acaaaacaga tggcgcttca aagttgatat
     7381 tgctctgttt cccatgcatg acttttggag ccaaacctag cttaccacca aagacttctg
     7441 caatggcttg gtgacccaaa caaatcccta gaatcggctt cttgcctgca aaatcacaaa
     7501 tcatgtcttc catctttcca gcatcaactg gccaaccagg accaggagaa aagaccagac
     7561 catctgcttt ttcagcttct tcatacagct tggaatcatc atttctcaga acctgaactt
     7621 ctgcaaaatt cccaatgtat tgggccaagt tataggtaaa agaatcatag ttgtcaatca
     7681 ataaaatcat ggtcttagtt ctccaattct agtcatagat tttgctttgt taatggtttc
     7741 ttggtattcg ttttgggcga tagagtcgta gacaatccct gccccagcct gcacataggc
     7801 tctttgattt ttgagaatca tggttcggat ggcaatggcc aaatccatat cacccgtcgc
     7861 agacaagtag ccgattgctc ctgcatatac gccccgtttt tccgtttcca gttcatagat
     7921 gcgtctcata gctcgaattt ttggtgctcc agaaacggtt ccagcaggaa gcgttgcttt
     7981 caaggcatcc atggcagtga gttctgcaag caaacgtccc ttgaccacac tggtcaaatg
     8041 catgacgtag cggaagagct ccacctccat atacttagta acttggacac tggccgtttc
     8101 agagatgcgg ccaatatcgt tacgccccaa gtctaccaac attcgatgtt ctgctgtttc
     8161 cttctcatca gagaggaggt cagtcgccaa ggccttgtct tcttcatccg tagcccctct
     8221 tggtcgcgtc cctgcaatcg gattggttgt cacgatgcca tttttgacag aaaccaaact
     8281 ttctggacta gctccgatga tttgataatc cccaaaatca tagaaataaa ggtaattaga
     8341 aggattagtc acgcggagat ttctgtagaa gtcaaatgga tttccagtaa cttctgctga
     8401 gaaacgctgg ctgagtacac attggaacat atcaccatta cgaatcaagt cgcgagcagt
     8461 ttctaccatt acctcaaact tatgtggagc gatatgcggt ttgaagtcaa gtggtgataa
     8521 atccaagtct tcaaattcat ttggagcagg aatgcgtaat tcctcaagca cttggttcaa
     8581 ggatttttcc aaggcctctt gactgcgctc actataaagt gcatcctcta tgacatgtat
     8641 cttctccttc ttgtggtcaa agactatata gctctcatag acaaagaaat gcatgtctgg
     8701 cgtcccaatt gtatcctcag ggatttgacc aatttcttca taaagcgaaa tcatatcgta
     8761 acccacaaaa ccaatggctc caccaccaaa aggtagctct gaatggtgct gactcttatg
     8821 aatcacttca taaaggaaat ccaagggatc ccgatcaatc acttgaccat tttgataaag
     8881 aactccattt tcaaacttaa tctcaaaaac aggattatag gctaggatag aaaaacgagc
     8941 tgtttccttg tctctcggaa tactctctaa gataaccttg tgttgcccct ttaagcgcat
     9001 ataagccaag attggtgata agacatctcc atgaatgatt cgttccattg taatttccct
     9061 ttcagttcta attctagttc gtagcgactg tatgaaaaat ccccacgcaa aataacttgc
     9121 gtgaggacga aattcgcggt gccacctcaa ttataggatt tctcctatct ctcattcctg
     9181 tctcagatat ctcctgtaac aggctgtgcg ataaagggca ctcccttgag aatgatgttt
     9241 tcttctctcg tttcagatga acccaacttt acagctttct ctgcttgttt tcagcaacca
     9301 caagctctct gtgagagaaa gaactgtaat ttttccatct attatttttt agcttctagt
     9361 agtctgcaat cgcagctagg tccttgcctc cacgaccaga gacattgatg aagagatgtt
     9421 catctcggta cacctttata ctcttcgaaa atctcttcaa accgcgtcaa cgtcgccttg
     9481 ccgtaggt
//
LOCUS       DAVLDI010000074         9295 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLDI010000074 DAVLDI010000000
VERSION     DAVLDI010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9295
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.075"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(112..471)
                     /locus_tag="VXD01_002017"
     CDS             complement(112..471)
                     /locus_tag="VXD01_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0602353.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPIIAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(770..1684)
                     /locus_tag="VXD01_002018"
     CDS             complement(770..1684)
                     /locus_tag="VXD01_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0602354.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LQDSPGTNNFSLPNVSPTYGQYYTNQSEVIIGKNDLVKVKNTLQYPYSTSAYVESEFR
                     GVKNGKDVTYRGSANFIKDNVLITAAHNIYKHEFGKDAEELYVTPARTPNSVPFGRIK
                     VKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLTGITVTITGY
                     PSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASNRVVGVHTLGDGAN
                     QINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(1834..1929)
                     /locus_tag="VXD01_002019"
                     /pseudo
     CDS             complement(1834..1929)
                     /locus_tag="VXD01_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411442.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(2006..2317)
                     /locus_tag="VXD01_002020"
     CDS             complement(2006..2317)
                     /locus_tag="VXD01_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002877158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0602355.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(2242..2484)
                     /locus_tag="VXD01_002021"
     CDS             complement(2242..2484)
                     /locus_tag="VXD01_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV0602356.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(2485..3117)
                     /locus_tag="VXD01_002022"
     CDS             complement(2485..3117)
                     /locus_tag="VXD01_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0602357.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(3131..4126)
                     /locus_tag="VXD01_002023"
     CDS             complement(3131..4126)
                     /locus_tag="VXD01_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV0602358.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKFPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERIEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(4123..4821)
                     /locus_tag="VXD01_002024"
     CDS             complement(4123..4821)
                     /locus_tag="VXD01_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV0602359.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(4898..5908)
                     /locus_tag="VXD01_002025"
     CDS             complement(4898..5908)
                     /locus_tag="VXD01_002025"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV0602360.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(5892..6899)
                     /locus_tag="VXD01_002026"
     CDS             complement(5892..6899)
                     /locus_tag="VXD01_002026"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV0602361.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(6886..7839)
                     /gene="mvaD"
                     /locus_tag="VXD01_002027"
     CDS             complement(6886..7839)
                     /gene="mvaD"
                     /locus_tag="VXD01_002027"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV0602362.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(7821..8699)
                     /gene="mvk"
                     /locus_tag="VXD01_002028"
     CDS             complement(7821..8699)
                     /gene="mvk"
                     /locus_tag="VXD01_002028"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV0602363.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(8821..9150)
                     /locus_tag="VXD01_002029"
     CDS             complement(8821..9150)
                     /locus_tag="VXD01_002029"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0602364.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFCKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFHRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVR"
BASE COUNT         2767 a         2138 c         1618 g         2772 t
ORIGIN      
        1 tatagacaac aagtcttttt cctaactaaa acactcataa agtatagaca attttagact
       61 actttggata tcttttggtt agtcattttc caaaactaat ttatctaatt tttaagttat
      121 atttgacttc atcttctcag taacatgagt ataaacactt aaaatctttg tttcattagt
      181 ataatctaca cgatccatta tcgctattat aggtacttcc aattcagcaa gcaaacttat
      241 atgcgaatat ctaaaaacat gagcagtcaa tacaaaatca tctttcttaa tttcactttt
      301 cctaaacctg tttttcaaaa agtaattgaa acaagttatc attaagggag aaccattatt
      361 tgtaaatata taatcacctt cttctaaaag aagatattct tttaaaattt ctaacactct
      421 atcactaata ccaattactc tatatgaagc taaacttttc ggactatcca aaaacacttc
      481 gttattggac gattacatta tagtaaaacg aaataagaac aggacaaatc gatcaggaca
      541 gtcaaatcaa tttctaacaa tgttttagaa gtagaggtgt actattatag tttcaatcta
      601 ctatacaaga cgaaattgaa gaaatctttc cattataaaa cgcatattat caaggttttt
      661 aaacacctaa taatatgcgt tttttcctat tttaaagact tttatccacc tattatacaa
      721 agttaagtat ccatcacagt ttacaattag ccttcattac ctaacccatt caccatcctt
      781 caagagagta acctttaaga accgaataaa taaatggcaa atttcgttca tttaatttaa
      841 ctgcactgtt aatttgatta gctccatctc ctaaagtatg cactcctact acgcggttac
      901 tagcatcata aactgtagat ccactagacc cctctaaagt atcaacttgg tagtccaaga
      961 acatgccatc atcacttaaa acttgttttt tatctgtata catttgatga attttaaaat
     1021 tatatgatgg atagcctgtg atagtcacag ttattcctgt caaatttttt tgactagtag
     1081 gaagacccaa agtccctaat tttgcaccaa tgggctcttc tagaattaat aaagccaagt
     1141 catattccct tgcatcctta gaatttaaat ttctaaattc ctttaaataa cgaacttctt
     1201 ttacttttat ccgaccaaac ggcacactat ttggagtacg agcaggagta acatatagtt
     1261 cttctgcatc tttaccaaac tcatgtttat aaatattatg agcagcagta ataaggacat
     1321 tatcctttat aaaattggca ctccctcgat aagttacatc tttaccattt ttcacaccac
     1381 gaaattctga ctctacataa gctgatgtag aataaggata ttgtaaagta ttttttacct
     1441 taactaaatc atttttacca ataatgactt ctgactgatt tgtataatat tgaccataag
     1501 tcggtgaaac attgggaagt gaaaaattat tagttcctgg actatcttgt aatgtctcac
     1561 ttacctcata ttcttcacct gtactagaaa taacactcaa agcagatact gtcgataact
     1621 ggctagccaa taaagtactc gcaataattg aaatacccaa ttttttataa acagttttct
     1681 tcattattgt atcctcctaa tgtaattata gcgtactatt ctaaatttct taatctacta
     1741 tagaatcaag aaatctacca ccttctttaa ataccctcca ttatcacata aacaggtaaa
     1801 cttttcaatt aatgactgcg cttttcaatc acgctagagg tacttacttg cttctttgat
     1861 actaagttca gccattcttt ccttgttttt ctcaataaag catgttaccc aagtgggatt
     1921 cgttctggtg gtcaatagcg acacgtctca gccagatatt atctgatagg ctccatttta
     1981 tactcaatga aaatcaaaga gcaaactagg aagctagccg cagattgctc aaaacactgt
     2041 tttgaggttg cagatagagc tgacgtggtt tgaagagatt ttcgaagagt attaagatta
     2101 tttcttctag ttcagagtgt tcatacacca aactccctac tactcgatct aggatatcta
     2161 ccgtgtccca ccaggatttt gtcacgacta actgctctag cttaggcaaa tcggtttcct
     2221 ttagataaga ctgcattgct ttcaaatagt tagcagccac atattggtat tctctaggat
     2281 ccttttccca gcaagtgtct gcaaaatccc aatcgataat ctttgttttt ttcgcttctg
     2341 gaaaatattt ttatagagtt tatttctttc aggcaccgca atacctagaa aagaaaattg
     2401 atggcgcata taggcttcca tggaccttgc ttttttagag tcttttgctg cttctagctc
     2461 ctcaagtaaa tctgctaaac tcatctaaaa ctcctcttgc cccaccaaat ggtgctgaaa
     2521 ggcatagaca gccgcctggg tacgatcgct gacttcaagt ttggcaagaa tattggacac
     2581 gtgggtcttg accgtcttga gagagataaa gaggtcatct gcgatgcgct gattttcgta
     2641 gcccttggcg atgagttgga gaacatctcg ctcacgcgca gtcaattctt catgaagttc
     2701 catatgattg cggtggtatt caaccttctt gctaacctct tgctcaatgg ccagctcgcc
     2761 agcagctacc ttactgacgg catgaagcaa ttcatctgca ctagaagtct tgagcatata
     2821 gcctttggca ccagcatcta agactggcat gattttttca ttgtccaaat aagaggtcac
     2881 aatcaaaatc ttggcttcag gccattcttt aaggattgct aaggttgcgt caatcccatt
     2941 catctcaggc atgacaatat ccatgacaat gacatctgga cgcagttcca aggccaagtc
     3001 aatcccttga gacccgttgg acgcctcacc cacaacttct acatcgtctt ggaggtcaaa
     3061 gtagcttttc aagcccaatc ggaccatttc atggtcatct actagtaaaa ttttcatctt
     3121 tactccttta tcattcctta tctaacaggg gaatacggat atcaaccgcc agcccttgct
     3181 tgggagctgt caagagttga actgttccag ccatatcttc aatccgctcc ttgatatttc
     3241 gcagtccata actcaagtcg tctaagctcc ctaactggaa accaatccca ttgtccacca
     3301 ccttcagttg caattcaaca tctgtctgat agaggtagac atctaggcaa gatgcctggg
     3361 catggcggag cgtattgcta atcaactctt gcaggatacg gaagatatgc tcctcgattt
     3421 tcttaggaaa tttcgtcata ttctgcttga gactaaccct aagatcactc ttgtcctcaa
     3481 gctcttttaa gagaatttga atcccttcta tcaagctctt ctgctccagt tcaactggtc
     3541 gcaaatgcaa gagcaaaacc cgcaaatcct tctgggctgt ttctaaaata gctgtgacac
     3601 tctgcaactg ggtctgcatc ttttctctat ccaatttcaa agcctgctga ctgatacccg
     3661 ataaaatcat gtgggccgca aacaactcct gactgactgt atcgtgcaaa tcccgagcaa
     3721 ttcgcttccg ttccttctcg atgatttcct cttcctgagc aaggctatga ttttcagctt
     3781 tttgaagagc ctctgtcaaa aggttaagtt tacctgataa ggacttgaaa ctggcatcca
     3841 aatctggatc tgcaacctga accacttctt gccctgccaa taaacgcttg agattagcct
     3901 gcatttttct tagagaaagc tcttcgatcc ctcgccaaaa cagggctaag agacaggtta
     3961 tggacatgct gaaaaccaac aataaaaaga caaatttttc tgttttttcg acatcgtgca
     4021 aaaagataga ccagtcaaaa tcaagtattt ccagcaagct gtgggagaaa aaaaagacaa
     4081 acaggaagga ggtgagagca ataatgacat aggcttgttt tttcatcctc taaccacctc
     4141 cacatcacca atcatagtgg tcaagaaaat cttgacactc ttgttactct tgagatagtc
     4201 ttttgtttct tgatgatagt gttcattgcg gagggctcgc ttgggctggt tgaaaaaagt
     4261 caaatcccca tagagacagt taacgctgag actgacttcc acatctacag gtacgatgat
     4321 tttggtcgtt cctaccatct ttctgaggat aatgacattg tcatgattgg ttaagatgac
     4381 cctctccaga tgaatagtgt ccttgcccat gaagcgaaag agattgatat catcgaattg
     4441 gcaagtctgg tagcttgaaa aatgatgaag atttccaaac caacgatttt tctccttctt
     4501 aaccgtcacg acctcttcaa aaaccaaatt ggtctgctct ttttcctggt tcatcatcgg
     4561 gtaaagaaga aagaggctat agataaccgc aacaaaaata gctagaatca caaaaggatt
     4621 gagcataacg atgaaaaaga agagaatggt tgccgctact aaaagaagat tatttccctc
     4681 tttaccagtg tagtagcgaa tcaaaagcaa aaagaggaat agtatcagca gaaaacgcga
     4741 aaaatgctct gataccatca aaatcagagc tcctgtcaga agacaggctt cgataaataa
     4801 aaagatttta aattttctca taggttcatc ctctcccttc tattttatca caattcaaaa
     4861 aagtcacctc agtctgagga tggaaaaaag gcgctggtta cgcctttttc atctgatcct
     4921 ttgcttcttt taattttcca taaagaagat agtctacttt ttgtagatct gctatggtgg
     4981 cacagttaag ggaacacata atcaagcgta ggtctgcttt ccagccttgg acaatgccaa
     5041 tcacttcttc aactgtgtag gtttcaacca attccagaac ggttcgtgac aatcccacag
     5101 acttagcacc aaaaaccaag cacttaatca tatccagcgg attccgaacc cctccactaa
     5161 ccaagagttc gaccttatct ttccattctt gggcattgag aagggcctgc atggtagact
     5221 gaccccattg attgaggtaa tcacgctggc cactacgacg gttttcgata taggcaaagc
     5281 tggtgccacc acgacccgat aggtccactg tacgaacacc gaattcatag gctctttcga
     5341 ttgtcttggc atccattcca aagcccactt ccttgaggac aataggaacg ggaatttgct
     5401 cgctataatc tgctagatgc gattgccagc ttctaaactt cctttctccc tcgggcatga
     5461 gtaattcctg catgacattg acatgcactt gcaatagaac aggattcatc tcttctacag
     5521 tctgaagtcc taactcgaca ggcttgtcca atccaatatt ggttccaagg aggagattgg
     5581 gatgactaga cttgacagaa aaagaatcat ccgttggatt tttgagggct gcgctataag
     5641 aacccgttac aaataaaata ccacaggatt ccgccacctg agccagcttt tgattgattt
     5701 ctcttccctt attacttcca ccagtcatgg cattgatata aaaaggaaag tcccactttc
     5761 gaccagcaaa ctctgtcgaa agatcgattt catccagatt gtaaagaggc aaggaagaat
     5821 gaatcagctc cacctcatca aagctattat aggaactttt ctgctcaagg gcatagagga
     5881 tatgctcgtc cttacgattt gtcgtcatgt cctatccttt cttgatataa gagctcaatc
     5941 cccagatcgg cccaacgatt ttttaaggtt ttggttgatt gcgcatcaaa actcaaggcg
     6001 atgccacagt caccaccacc agcaccacta ctcttggcaa cggcctgcaa atcttgactg
     6061 gcttctttca actgtctaag caaaggcgtg taaatatctg tactcaagcc ttctaaaagc
     6121 ttgctggcta cttctacttg ctcgataact ttttcggctt tcccctgctc caaggcttcg
     6181 accaaagaaa ccaccgtttc ttttgaggaa cttaaaaaat tttgattgat attttgcttg
     6241 atttgctgga ccatgtgact cgatacagcc acttccttgg tccatcccac taagaaatca
     6301 cattctaaag ttggtttcac ttgtgagata aaaaatcccc aatcacgctc cagaactgtc
     6361 gccaagtttt cttcttctaa ccaagcagcc accttctggc gatcaaatga ctggtagaga
     6421 accaaatcct ctgccacaat acaggcaagg tcgcccatgg aaccattgtc tcctcgcttg
     6481 agcaagacag cgctagtcag cttgaacaag agattctgat caaccgaaag attatagaga
     6541 gccagtaaag ccttgacaac caagacaacg acgctgccac tagaacctag accaaacttt
     6601 ttcccttctc gttccatttt gccacagatt tttagggaaa aaggtcttaa attctgaccg
     6661 cgaacagcga ggaagtctcc catcaaagca atcgtttctt gaatcaagct gtagtcagga
     6721 ttaggcctta agtccactgc gaaatcaaac atatctgaat agatacggta gctgtcagaa
     6781 aaagcaattt cagccctcat atagatggga atatccttta tcaaagctaa ctgccctggc
     6841 tctaaaatag catattcacc tgcccaatag agttttccgc aagttttaac agcaatcatc
     6901 ttgactcaaa tcctttgttt ttgacacaat caagcgataa cgctgaccga aaatttctga
     6961 taaatgctcc aagtctttct cctgacagaa gaccttaaca ttgggaccag catccatggt
     7021 aaagtagcag gcctctcctt tctcacgaag ctggcgaaca aagtccatag cctcataaga
     7081 ggcatccgtc agataagaaa aggctggact agcagtcttt gtcgtagcat gcatagccag
     7141 ggcatttttc tccgttaatt ctccaatctt ggcaaaatca ttttccttga gataaatcag
     7201 catatcctga tagtccttct cagactgacg aacccagtcg tcgaaagtcg tcgaggtttc
     7261 cacacaaagt ttcatcccgt cacggctaga gattggtttt ttcttgtcct ctagcaccaa
     7321 cataatcata gctagtttca agtctgtctc tacagggtaa atttctccac tatccttatc
     7381 ccaggctcct agtggtccat aaaaactccg agaagaagag cctgaggcaa acttggcttc
     7441 ctgcgctaac tgacttctat ccaatccaag cttgaaataa gcattacaag ccttgaccag
     7501 ggcggacaaa ccactagaac ttgaggacag gcccgctgcc gtaggcatat tgttttgagt
     7561 atcgatacgg acaaagccct caccagctgg acgataacgg tcaataatct tactcatctt
     7621 ggcatgctcg acctcatttt gtagctgacc attgatgtaa aattcgtcag ctgttacatt
     7681 ggctggtaaa ggcgacaagg tcgtctctgt atacatattt tccaaagtta gagaaatact
     7741 gctagtagca ggcaccatct ctttttcttt tttctttccc caatatttga taatagcaat
     7801 atttgcgtag gaacgtactg ttacaggctc tctatccatg tctgaacagc tcctttctct
     7861 tctaatcttt ctgctagttc ttgtgcgtgt gtcaaattgg ttaccaaggc tatgatacaa
     7921 cctcctagcc caccaccgct catcttggca cccagagcac catggctaag agtcgtttca
     7981 accaaaaagt ctgcctcagg gctactgact ccaatttctt ttaaatgtaa atgcgcttga
     8041 ctgaggattt gtcccagtcc ttcagcatct ttttgtgaaa tcgcaacttc tgcttgctgg
     8101 gttaattctc ccaaggcatg caaaaacggt agggcatcct tgcccttatt ttgaaccact
     8161 tggatggctt cacgagtatg accataaaca cccgtatcgg caatcaccaa ataggcggat
     8221 aaatccatct caagttctgt aaatcctacg ttcttgataa agcgaatagg ttggtcactg
     8281 agacaggtct tagcatccaa accactagga ttcatatggg caatcatttc agctcgattg
     8341 accaagattt ctagtacatc atgaggcaga tcagcctgat agtagtcaaa taccgcacga
     8401 atggccgcta tgctgatagc cgctgacgaa cccatccccc gtttctcagg gatagccgag
     8461 tcaatctcac aacgaatgca ggcttctgtg atatccaaat actccagtga ggcataaacc
     8521 gccatggaca aggtatcctc ctcataaagg cgccaaggac tctctgcagg aactacctta
     8581 caggtcacct ccacctccaa aagaggcagg gaaatggcag gataaccgta aacgaccgca
     8641 tgttccccta ttaaaattat cttactatgt gcctgaccga caccaacttt ttttgtcatt
     8701 ttttcctttt actagacgaa aaaacgtctt atttttcata caagtattaa ttctttccta
     8761 tctattttat tatattttca caaaaaaagc gattgtttcc attcacaatc gcttctttca
     8821 ttaccgaacc cattcaccat tataattgac agaatagcca tctacagtcg tattcactgc
     8881 caaggcacct gagctataag cgtagtacca tctgccattg acctggaacc aacctgtcgt
     8941 catagaacga tgaaagaaac tccataccat taagtaaaga ggaaagtcat gagggagcat
     9001 gcgccattga caacctgttt tagtgacgta caaagtttca ttaacaagta ctcgtttcgg
     9061 ccatttatag gtgcggtgtt tgcagaaata gggttcaatc ttcgcccatt cttgatcgtt
     9121 taaatcagta tcatatgctt tgcgtgtcat aactctagtt taacattttt ttgtgaatac
     9181 aggttctaaa taatcgacca cgaaaatttc ttaagtggaa aacgccttat gaagtatgct
     9241 acgggaaact tatgcactta atttgacaac tcaatatgta aaaatatata ctata
//
LOCUS       DAVLDI010000075         9038 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLDI010000075 DAVLDI010000000
VERSION     DAVLDI010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9038
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.076"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            151..306
                     /locus_tag="VXD01_002030"
                     /pseudo
     CDS             151..306
                     /locus_tag="VXD01_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            506..3781
                     /gene="rexB"
                     /locus_tag="VXD01_002031"
     CDS             506..3781
                     /gene="rexB"
                     /locus_tag="VXD01_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV0602365.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKENSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLGLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3778..7428
                     /gene="addA"
                     /locus_tag="VXD01_002032"
     CDS             3778..7428
                     /gene="addA"
                     /locus_tag="VXD01_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV0602366.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILNQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQKGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALKMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(7390..7602)
                     /locus_tag="VXD01_002033"
     CDS             complement(7390..7602)
                     /locus_tag="VXD01_002033"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602367.1"
                     /translation="MDRTDEVSSKHCFEVVDRTDEVSSKHCFEVVDRTDEVSNHIYSK
                     AKLTWFEEIFKEYKLYFYNLNLVFTE"
     gene            7733..8911
                     /locus_tag="VXD01_002034"
     CDS             7733..8911
                     /locus_tag="VXD01_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602368.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDCQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         2798 a         1889 c         1908 g         2443 t
ORIGIN      
        1 tgtactattt ttggttcatt ttactatagt agattgaaat aagatacgaa cagcttgatt
       61 agggaaatca aattaatttc tagaaatatt ttagcatcca cggtgtacta ttatagtttc
      121 aatttactat agttcaatca ttctatcaag aatattgaat atataaaggc acgtaatatt
      181 aaaacttctt ctgatatcga attagagtcc gatgttgatg gcgataaatc agacaatcta
      241 ccagtcgaca ttaagatact gggacaacac attgaagtgt attccgtacc taagaaacaa
      301 tcataaaact caaagccttg ttaccgaggc ttttttatta tgtgattttc agtagccaga
      361 cttattctat ctaatacaag taaagctaag tatttaagat ttagcagatg atgaagaaaa
      421 gaaaggatgg cctaaatatt ttaacagatt tacgaggcta atcatggtat aatatagggt
      481 gatgaaaaat tccaacgagg ctgagatgaa attactttat actgatattc ggacttcttt
      541 gacagaaatt ctaacaagag aggcagaaga gctagttgca gctggcaagc gggtcttcta
      601 cattgccccc aactctcttt cttttgaaaa ggaacgcgcc gtgctggaat gcttgtccca
      661 gcaggcttct ttttcgatta ccgtcacgcg ctttgctcaa atggctcgtt atctggtctt
      721 gaatgattta ccagctaaaa ctactcttga tgatatcggt cttgggttgg ccttttacaa
      781 atgccttgcc gaactcgatc ccaaggactt gcgtgtttat ggcgctatta agcaggatcc
      841 tcaattgatc cagcagttaa ttgagcttta ccatgagatg accaaatccc agatgagttt
      901 tttggacttg gagaatttaa cagatgagga taagagggcg gatttactct tgatttttga
      961 gaaagtaaca gcctatctta atcaaggtca gttagcccag ggaagtcagt tgtcccattt
     1021 gattgaggct attgagaatg acaaggtaag tagtgatttt aatcaaatca ccttggtcat
     1081 tgacggcttt actcgttttt ctgctgagga agagcgggtt gtggacttac ttcacggcaa
     1141 aggtgttgag attgttatcg gggcttatgc tagtaagaaa gcctatacca gtccttttag
     1201 cgagggcaat ctctaccaag ccagcgtaaa atttctccat catctggctt ctaaatacca
     1261 aacgcctgct caggactgtt ctcaaactca tgagaagatg gatagttttg acaaggcctc
     1321 tcgtttgttg gagtcttctt atgacttttc agaactcgct ttggatgtcg atgagaaaga
     1381 ccgtgaaaat ttacaaatct ggtcttgttt gacgcaaaag gaggagttgg agctagtagc
     1441 ccgtagtatt cgtcagaaat tacatgagaa ctcagacctg agctacaagc attttcgtat
     1501 tctcttgggg gatgtagctt cttaccagtt atctctcaaa accatttttg accagtatca
     1561 gattcctttt tatcttggta gaagcgaagc catggctcat catcccttga ctcagtttgt
     1621 cgagtctatt ttagctttaa aacgttaccg ttttcgtcag gaggatttga ttaatcttct
     1681 tagaactgat ttgtatactg acctcagtca gtctgatatt gatgcttttg agcaatatat
     1741 ccgctatctt ggtatcaatg gcttgccagc ctttcagcaa accttcacca aatcccacca
     1801 tggaaaattt aatcttgagc gtttgaatgt cctccgcctg agaattttag cacctcttga
     1861 aaccctcttt gccagccgaa aacaaaaggc tgaaaaactc ctacaaaaat ggagtgtctt
     1921 tctaaaagaa ggagctgtga ccaagcagtt acaagatttg acaaccactt tggaagctgt
     1981 agaacaggaa agacaagccg aagtttggaa ggctttctgc catgttttag aacaatttgc
     2041 gactgttttt gctggttcac aggttagtct ggaagacttc ctagccttgc tccattctgg
     2101 aatgagtttg tcccaatacc gtaccattcc agcaacagtg gacactgttc tggtgcagag
     2161 ttacgatttg attgcaccat tgactgctga ctttgtctat gctattggac taactcagga
     2221 caatttacca aaaatttctc aaaacaccag tcttctgaca gatgaagaaa ggcaaaatct
     2281 aaaccaagcg accgaagaag gcgttcaatt actgattgcc agcagtgaaa atctcaagaa
     2341 aaatcgctac actatgcttt ccttggtcaa ttctgctcgt aagcagttgt tcttgtcggc
     2401 tccaagcctt tttaacgaaa gtgaaagtaa ggaatctgcc tatcttcaag agttgatcca
     2461 ttttggattt aggcggagag agaagaggat gaatcacaaa ggactgtcta aggaggatat
     2521 ggggtcctat cacagtcttt tgtctagtct ggttgcctat caccagcagg gtgagatgag
     2581 cgatactgag caagatttga cttttgtcaa ggttctgtcg cgtgtcatag gtaaaaaact
     2641 agatcagcaa ggtctggaaa atccagccat cccaatcagt ccaagcagca agaccttagc
     2701 caaggacacc ttgcaagctc tctatcctgc caaacaggag ttttacctgt ctacgtcggg
     2761 tttgacagag ttttatcgca atgaatacag ttatttccta cgctacgttt taggcttgca
     2821 ggaggaatta cgtttgcgtc ctgatgcccg tagtcacggg aatttcttgc atcgtatctt
     2881 tgaacgcgcc ttacagttgc ctaatgaaga ttcctttgac caacgtctag aacaagctat
     2941 tcaagaaacc agtcaagaac gcgaatttga agctatttat caagaaagtt tggaagccca
     3001 gtttaccaag gaagttttgc ttgatgttgc acggacgact ggacatattc tccgacacaa
     3061 tccagccatc gaaaccatca aagaagaagc aaattttggt ggaaaagacc aagcctttat
     3121 tcaattagac aatggacgca gtgtctttgt acgaggcaag gtggaccgga ttgaccgttt
     3181 gaaagctaat ggagcgatag gagtagtaga ctacaaatcc agtctgactc agttccagtt
     3241 tcctcatttc tttaatgggc tcaattctca gttaccaacc tatcttgctg ccctaaaaag
     3301 agaaggggag cagaactttt tcggcgccat gtacttggaa atggctgaac ctgtccaatc
     3361 tctgatggcg gtaaaaagtc tggcaggagc agtggtagaa gccagcaaat ctatgaaata
     3421 ccaagggctc ttcttggaaa aagaaaacag ttatttaggc gaattttata acaaaaacaa
     3481 ggctaatcaa ctgacagatg aggaatttca gctcctactg gactacaatg cctatcttta
     3541 caagaaagct gctgagaaga ttttagcagg ccggttcgcc atcaatcctt atactgaaaa
     3601 tggcagaagc attgccccat acgtccagca acatcaggct attacaggct ttgaagccaa
     3661 ttaccatctg ggccaagccc gtttcctaaa aaagttgggc ctagctgatg gcaagcgtct
     3721 ggtcggagaa aaactcaagc aagcttggtt tgaaaaaata agagaggagt taaatcgatg
     3781 aagcttattc cctttttaag tgaggaggag attcaaaaac tgcaagaagc agaagcaaat
     3841 tcgagcaagg aacaaaagaa aactgccgag caaatcgaag ctatctacac ttctggccag
     3901 aatatcctgg tctcagcatc ggctggttct ggaaagacct ttgtcatggc agagcgcatt
     3961 ctgaaccaat tggcgcgtgg tgtcgaaatt tctcaactct ttatctcaac ctttaccgtc
     4021 aaggctgcaa ctgaacttaa agaacgttta gagaaaaaaa tcagcaagaa aattcaagaa
     4081 acagatgatg tcgacctcaa acaacacttg ggacgccagt tggcagactt accaaacgct
     4141 gccattggaa ccatggactc tttcacacaa aaattccttg gcaaacatgg ttatctgctt
     4201 gatattgcac ctaatttccg tattttacaa aaccaaagcg agcaacttct tctcgaaaac
     4261 gaagtctttc atgaggtctt tgaagcgcat taccaaggta aacagaaaga gacctttagt
     4321 catttgctga aaaactttgc tgggcgtggc aaggacgaac ggggtctgcg ccagcaggtc
     4381 tataaaatct atgacttcct ccaatccacc agtaatcctc aaaagtggtt gagtgaatct
     4441 ttcctcaaag gctttgagaa agctgatttt accagtgaaa aagaaaaact gactgagcaa
     4501 atcaaacaag ccctttggga tttggaaagc tttttccgtt accatctgga taacgatgcc
     4561 aaggagtttg caaaggctgc ctatttagaa aatgttcagt taattctgga tgaaattggc
     4621 tccctaaatc aggagtccga tagtcaggct tatcaggcag tgcttgcgcg tgttgtcgcc
     4681 atctctaagg agaaaaacgg tcgagctctg actaatgcca gtcgtaaggc tgatttgaag
     4741 cccctggctg atgcctacaa cgaagagaga aagacccagt ttgctaaact aggacaatta
     4801 tcagaccaga taaccattct cgactatcaa gaacgttatc atcaagacac atgggaacta
     4861 gctaaaacct tccaaacctt tatgagtcat tttgtggagg cttatcgtca gcgcaaacgc
     4921 caggaaaatg cctttgaatt cgctgatatc agccattaca ccattgagat tttagagaat
     4981 ttcccacaag ttcgtgagtc ttatcaggag cgcttccatg aagtcatggt cgatgagtat
     5041 caggatacca accatattca agaacggatg ctggaattgt tgtctaatgg ccacaatcgc
     5101 tttatggtgg gagatatcaa gcaatccatc tatcgtttcc gtcaggcaga cccgcagatt
     5161 ttcaatgaga aattccaacg ctatgcgcaa aatccccaaa aaggcaagct cattctcctc
     5221 aaggaaaatt tccgtagtag ttcagaagtg ctgtcagcaa ccaatgatgt ctttgaacgt
     5281 ctcatggacc aagaggtcgg cgaaatcaac tatgataaca agcaccagct tgtttttgcc
     5341 aataccaaac tgactcccaa tccagacaac aaggcagaat ttctcctcta cgacaaggac
     5401 gatacaggtg aggaagaaga gagtcaaaca gaaacgaaac taacaggcga aatgcgctta
     5461 gttatcaagg agattctgaa acttcatcaa gaaaaaggtg ttgcctttaa ggaaattgcc
     5521 cttctgacct ccagccgcag tcgtaatgac cagattctcc tcgccctgtc tgagtacgga
     5581 attcctgtca aaactgacgg agagcaaaac aattatctcc aatccctaga agtgcaagtc
     5641 atgctagaca ctcttcgtgt cattcacaat cccctgcaag actacgcctt ggttgccctt
     5701 atgaagtctc caatgtttgg ttttgatgag gatgagctag cacgtttgtc ccttcagaaa
     5761 gcagaggata aagtccacga aaatctctat gaaaaactgg tcaatgcaca aaaaatggca
     5821 agtagtcaaa aaggtttgat tcacacagct ctagctgaaa aactaaagca attcatggat
     5881 atcctagctt cttggcgctt gtatgccaaa acccactctc tctatgactt gatttggaag
     5941 atttacaacg accgttttta ttatgactat gttggggctt tgccgaatgg tcctgctagg
     6001 caggccaatc tctatgccct agcactgcgt gctgatcaat ttgaaaagag caatttcaaa
     6061 ggtttgtcgc gttttattcg tatgattgac caagtcttag aagcccagca cgatttggca
     6121 agcgtggccg tcgcaccgcc aaaagatgca gtagagctca tgaccatcca caagagtaag
     6181 gggctggagt ttccttacgt ctttatcctc aatatggatc aagatttcaa caagcaagac
     6241 tctatgtcag aagtcattct cagtcgtcag aatggtcttg gtgtcaaata tattgccaag
     6301 atggagacag gggcagtaga agaccactat cctaaaacca tcaaactctc cattcctagc
     6361 ctgacctata ggcagaatga agaggaatta cagctagcaa gctattctga gcagatgcgt
     6421 ttgctgtatg ttgctatgac gcgggctgag aaaaagctct atcttgtcgg caagggttct
     6481 cgtgaaaagc tggaagccaa gcaataccca gcagccaaaa atgggaaact aaatagcaat
     6541 actagactgc aagcacggaa tttccaagat tggctttggg ctatcagtaa agtgtttact
     6601 aaggacaagc tcaactttag ttatcgtttt attggcgaag atcagttgac cagagaagct
     6661 atcggagagt tggaaaccaa gagtcctctc caagatagct cccaagcaga caatcgtcag
     6721 tcagatacca tcaaagaagc tctgaaaatg ctgaaggagg tggaagttta taatactctt
     6781 caccgcgcag ctattgaact tcctagtgtt caaaccccaa gtcaaatcaa gaaattctac
     6841 gaaccagtta tggatatgga aggtgtcgag attgctggtc aaggtcagtc agtaggcaag
     6901 aaaatcagct tcgatttgcc agatttttca acaaaagaaa aggtaactgg agctgagatt
     6961 ggtagtgcta ctcacgaact catgcagaga attgacctca gccagcaact aacccttgct
     7021 agcctaacag aaacactcaa acaagttcaa actagccaag ctgtcagaga caagatcaat
     7081 cttgataaaa ttcttgcttt ctttgacaca gtactcggtc aggaaattct tgctaatacc
     7141 gaccatctct atcgcgagca acctttctcc atgctcaaac gagaccaaaa gagtcaggaa
     7201 gactttgttg tccgtggtat ccttgatggc tatctgcttt acgaaaacaa aattgttctg
     7261 ttcgactaca agacagaccg ctatgatgaa ccaagtcaac tcgtagaccg ctatcgtggt
     7321 cagttagctc tatacgaaga ggctttatca cgagcctatt cgattgaaaa tattgaaaaa
     7381 tacttgattt tactcggtaa agacgaggtt caagttgtaa aagtataact tatactcttt
     7441 gaaaatctct tcaaaccacg tcagcttcgc cttgctgtat atatggttac tgacttcgtc
     7501 agttctatcc acaacctcaa aacagtgttt tgagctgact tcgtcagttc tatccacaac
     7561 ctcaaaacag tgttttgagc tgacttcgtc agttctatcc acaacctcaa aacagtgttt
     7621 tgagctgact tcgtcagttc tatctacaac ctcaaaacag tgttttgagc tgactgcgac
     7681 tagctttcta gtttgctctt tgatttttat tgagtattag aaaggagacc tcatgacact
     7741 tccagttaga aaatccctgc acgatgcagt tttacaggct tcgaaagcgg atacttggga
     7801 acaagctacc aaggaatgga atgaagtttc cttgattttt aacggtatcg gccgtagcaa
     7861 ttgtgtctgt ggaaatgcca tcaaatacgc ttatgaactc tttaacggtg tcacaggcca
     7921 acgcctcttt ccaattggta gcgactgtgt tcgtcatttt catcgattgt cccttgacca
     7981 gcaattggaa gaggaagaaa aactgctcag aaaggttgaa aatctaacca gaaaagctca
     8041 gaaaaaggaa aaaatcaagg tcaataaaag tgactttgac gagcgacttc taaaatggct
     8101 ctgggaaaaa ggtgttttca aacccaatcg tggcaatcaa tttgcgcctg agagagactg
     8161 ccagcttttc ctagaagtct ttcagggagg aagttggacc aaggcggaac caaagaaaaa
     8221 ggctcggatg gaagaagtcc ttgaaaagtg tatcaaaccc tttttacttg ggaaatcgga
     8281 tgaccaactc taccttgtca agctaggcaa ggagaaaatt gactacgaac aagaactccg
     8341 tatccaggca gagaaagaac gcaagaagag ggataaaatc gccaagcaat atgcagacaa
     8401 tctggttcta gccatgggac ccgcagagcg tgcttatcaa gattactttg gctttacaga
     8461 gaccctgact caagaagaac gcaagtggga aaaaattctt tttggtaaaa atagagcaga
     8521 acgggctatc aaggccaaac aataccaaaa agagctggaa aaagaccaac gaattgccag
     8581 tcaggatcca attgaaagaa aacagaagca gacttggctc ctcaattcct attttcgtga
     8641 gcttcctgaa gaaaaagctc gattttctag gctcttatta gaatatcgaa aaaatggtga
     8701 agtacccttt tcaactgaat acctgtcaga tcatctcatc gactttttct ataaaatgaa
     8761 agcctttgaa tttgaaatcg caccagaaca agtccgagat tttctaaaaa aaagcctgca
     8821 ggaagaccat cgctcatcag cacaaggaag ctggatagaa ggaattctcc tcaactgcct
     8881 caaaccattt ttagaacgat tagtgatatg agtaacacct accgtgtaaa tttcatggta
     8941 ggtgttattg tacctcaaaa taatataaaa caaagtatga aagcgcatct caattttaag
     9001 acttttttgt aaattaagag tataattaag gtatactg
//
LOCUS       DAVLDI010000076         7754 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLDI010000076 DAVLDI010000000
VERSION     DAVLDI010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7754
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.077"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..262
                     /locus_tag="VXD01_002035"
     CDS             <1..262
                     /locus_tag="VXD01_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEV0602369.1"
                     /translation="DSIFSTYELKMQDATISSSELEFLCDLLLYKTLDQGRYNVEGPL
                     VLARYLLGCEFEVKNLRMIISALQNTIPFESIKERIRPHYGS"
     gene            252..572
                     /locus_tag="VXD01_002036"
     CDS             252..572
                     /locus_tag="VXD01_002036"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEV0602370.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            635..2410
                     /locus_tag="VXD01_002037"
     CDS             635..2410
                     /locus_tag="VXD01_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEV0602371.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTISIGQKVSTGDILGTVKETEVVNHKIMVPYGISGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQALGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDDKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSENERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIIEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIQLILETGGL"
     gene            2411..3796
                     /locus_tag="VXD01_002038"
     CDS             2411..3796
                     /locus_tag="VXD01_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEV0602372.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVKFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            3819..4430
                     /locus_tag="VXD01_002039"
     CDS             3819..4430
                     /locus_tag="VXD01_002039"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEV0602373.1"
                     /translation="MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKAFAVAKSLKNSLMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            4506..4709
                     /locus_tag="VXD01_002040"
     CDS             4506..4709
                     /locus_tag="VXD01_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602374.1"
                     /translation="MTVSGYLFQNFGLLDNENVSTDLDLGLISRKCNFKEKDKLKKDV
                     LARVGLTHIHLEQKIYELSGGEA"
     gene            4806..4916
                     /locus_tag="VXD01_002041"
     CDS             4806..4916
                     /locus_tag="VXD01_002041"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602375.1"
                     /translation="MKLLLDMKNENRLIIIATHNPDIWNQADEVINLNQL"
     gene            complement(5016..6367)
                     /locus_tag="VXD01_002042"
     CDS             complement(join(5016..5926,5926..6367))
                     /locus_tag="VXD01_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSpn4 family transposase"
                     /protein_id="HEV0602376.1"
                     /translation="MKLSYEDKVQIYELRKQGYSLEKISNKFEINNSNLRYMIKLIDR
                     YGIEFIKKGKNRYYSPELKQEMIDKVLHENWSQDRVSLKYALPNRGMLPNWLAQYKKN
                     GYTIVEKTRERVPKMGRKRKKTWEEMTELERLQEENERLRTEVAYFKKVKRAGRQGRS
                     PRARKAEIVREMASGGFQLDLLLETARLARSTYYYQLKGLGGLDKDKDLKAEIQAIFT
                     EHKGNYGYRRVTLELRNRGFVVNHKKVQRLMKVLGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPASSQKLYLSPVLDGFNSEIIAYNLSTSPNLEQ
                     GKAMLNQAFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKTFQSLNQLEQAIVDYIDYYNNKRIKIKLKGLSPVQYRTKSFG
                     "
     gene            6952..7170
                     /locus_tag="VXD01_002043"
                     /pseudo
     CDS             6952..7170
                     /locus_tag="VXD01_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7470..7754)
                     /locus_tag="VXD01_002044"
                     /pseudo
     CDS             complement(7470..7754)
                     /locus_tag="VXD01_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2500 a         1238 c         1513 g         2503 t
ORIGIN      
        1 agattcaatc ttttcaactt atgaattgaa gatgcaggac gcaacaattt catcttctga
       61 gttagaattt ttatgtgatt tactattgta taaaacttta gatcaaggaa ggtacaatgt
      121 agaggggccg ttagttcttg ctagatattt attgggatgt gagtttgaag taaagaatct
      181 cagaatgatc atatcagctc ttcaaaatac aattcccttt gaatcaataa aagaaaggat
      241 acgcccacat tatggaagct aataagtata aaattggcat aattggtagc cgtgatatta
      301 ttttaccatt tagcatgatt gggtttgata tatttcctgc ctaccaagaa caagaagcta
      361 taaatacact aagaaaatta gctcaatctg attatggtgt catttatatc actgaagaca
      421 ttgcttcaat gatattagat acaattcgcc attatgattc ccaagttgtg cctgctatta
      481 ttttattacc gactcataaa caaggtttaa atttaggatt aaaacgtata gaggataatg
      541 tagagaaagc agtaggacac aatattttat aataatgtac aaaattgtct gtaatattat
      601 tctataattt ttggacttag taaggagaat aactttgact caagggaaga ttataaaagt
      661 atcgggacct ctagttattg catcaggtat gcaggaggct aatattcaag atatttgccg
      721 tgtaggtaag ctagggttaa tcggtgaaat tattgaaatg agaagagatc aggcatctat
      781 ccaagtctat gaagaaacat ctggtcttgg tccgggagaa cctgttgtta caactggaga
      841 acctctctcg gttgaattag ggcctggatt gatttctcaa atgtttgatg gcatacaacg
      901 cccattagat cgatttaaat tggctactca taatgatttt ctagttcgtg gggtagaagt
      961 tccaagtttg gatagagata ttaagtggca ttttgattcc actatatcaa ttggtcaaaa
     1021 agtgagtacg ggtgatattc ttggaactgt caaggaaacc gaagtagtta atcataaaat
     1081 tatggttcct tatggaatat ctggcgaagt cgtttctatt gcctctggcg attttacaat
     1141 tgatgaagtt gtatatgaaa taaaaaaatt ggacggtagt ttctataaag gaacacttat
     1201 gcaaaaatgg cctgtccgca aggcgcgtcc tgtttctaaa cgtttaatcc cagaagaacc
     1261 attaatcaca ggtcaacgag ttattgatac attctttcca gtaaccaaag ggggagcagc
     1321 agctgttcct ggaccgtttg gagcaggaaa gacagttgta caacaccaag tagctaaatt
     1381 tgccaatgtt gatattgtta tttatgtcgg ttgtggagaa cgtggaaatg aaatgacgga
     1441 tgtactgaat gagtttcctg agttgattga ccctaataca ggacaatcaa ttatgcaacg
     1501 gacagttctg attgctaata cttcaaatat gcctgttgct gctcgtgagg cttcaattta
     1561 tacaggaatt accatggctg agtattttcg tgatatgggc tactctgtcg ccattatggc
     1621 tgattcgact tcacgttggg cagaagcgct acgtgaaatg tcaggacgtc tagaagaaat
     1681 gcctggtgat gagggttatc ctgcttatct tggaagtcgt atcgctgaat attatgaaag
     1741 agcgggacgt tctcaggctc tagggcttcc agaacgtgaa ggaacgatta ctgctattgg
     1801 agctgtatcg ccacccggtg gagatatttc agaaccagtt actcaaaaca ctttacggat
     1861 tgtgaaagtt ttttgggggc ttgatgctcc gttggcacag cgacgtcatt ttcctgcaat
     1921 taactggctt acctcttatt cactctataa agacagtgtg ggaacttata tagatgataa
     1981 agagaagaca gattggaata gtaaaataac tcgtgcgatg aactacttac aacgggaatc
     2041 tagtttagag gaaattgttc gtcttgttgg aattgattct ctgtctgaaa atgaacgact
     2101 aacgatggaa attgctaaac aaattagaga agattatttg caacagaacg cttttgattc
     2161 ggtagataca ttcacttcgt ttgcaaaaca agaagcaatg ttaagtaata tcctaacttt
     2221 tgctgatcag gcaaatcatg ctttagagtt gggttcttac tttacagaga ttatagaagg
     2281 taccgtggca gttcgagacc gtatggcgag aagtaaatat gtttcagaag atagattaga
     2341 tgaaatcaaa attatttcaa atgagattac acatcaaatt caattgatat tagaaacagg
     2401 aggtctataa atgagtgtta taaaagaata tagaactgct agtgaagttg ttgggcctct
     2461 tatgattgtt gaacaagtta ataatgtgtc ttacaatgag ttagttgaaa ttcaacttca
     2521 taatggagaa attcgtcgtg gacaagtttt agagatccac gaagataaag caatggttca
     2581 gctttttgaa ggatctagtg gaataaattt agaaaagtct aaaattcgtt ttgctggtca
     2641 tgcactagaa ttggctgtat ctgaggatat ggttggtaga atttttaatg ggatgggaaa
     2701 accaattgat ggtggaccag atttaattcc agagaaatat ttagatattg atggtcaagc
     2761 tattaatcct gtatctagag attatccaga tgaatttatt cagacaggga tctcctctat
     2821 tgatcatttg aatactcttg tacgtggtca aaaattacca gtattttcag gttcgggctt
     2881 acctcataat gaattagcag ctcagatagc aagacaagcg actgttttaa attctgatga
     2941 aaattttgcg gttgtatttg cagcaatggg tattactttt gaagaagctg agttctttat
     3001 ggaagaactc agaaaaacag gagcgatcga tcgttcagtc ttatttatga acttggcaaa
     3061 tgatcctgca attgagcgta ttgcaactcc ccgcattgct ttaactgcgg cagagtatct
     3121 agcttttgaa aaagatatgc atgttctagt tatcatgacg gatatgacta actattgtga
     3181 agcgttacgt gaagtctcgg cagctcgccg tgaagttcca ggtagacgag gctatccggg
     3241 atatttatat acaaatttat caactctata cgaaagggct ggtcgcttag ttggtaaaaa
     3301 aggttcagtg acacagattc ctattttaac aatgccagaa gatgacataa cacatccaat
     3361 tcctgattta actggataca ttactgaagg gcaaattatt ttgtcgcatg agttgtataa
     3421 tcaaggttat cgtccaccaa tcaatgtttt accttctctc tctcgattaa aagataaggg
     3481 atctggagaa ggtaaaactc gtggagatca tgctccaact atgaatcaac tgtttgcagc
     3541 ctatgcccaa gggaaaaagg ttgaagagtt agcagtagta ttaggagaat cggctttatc
     3601 tgatgtagat aaattgtatg tgaagtttac aaagcgtttt gaagaagagt acatcaacca
     3661 aggattttat aaaaatcgaa atattgaaga tacgttgaat cttgggtggg aattactatc
     3721 aattcttcct agaacagagt taaaacgtat caaagatgat ttgcttgata aatacttacc
     3781 tttggtagaa gtttaatcca gaaatggagt gattatctat ggtgcgtttg aatgtaaaac
     3841 caactcgtat ggaattgaat aacttaaagg aacgtttgaa aacagctgaa cgtggacata
     3901 agttattaaa ggataaaaga gatgaattga tgaggcgatt tatttctttg attcgtgaga
     3961 ataatcaact tcggaaagaa gtagaaagtt atctaattga taatctaaaa gcctttgcag
     4021 ttgctaaatc attaaagaac tctctaatgg tggaggaatt attttcaatt ccatcgaaag
     4081 aaattgaatt atttgttgag aaagaaaata tcatgagtgt aacagttcct agaatgcata
     4141 tgaatattac ttctcaaaat gagaacagtg aatacagcta tttatcttct aatagtgaaa
     4201 tggatgatgt atttgctaca atgaatagtt taattgataa attactaaga ctggcagaag
     4261 ttgaaaaaac gtgtcagtta atggctgatg aaatagaaaa aacacgtaga cgtgtaaatg
     4321 gattagaata ttcgattatt ccaaacttgt cagaaactat tcattatata gaattgaaac
     4381 tagaggaggc agaaagagcc aatttagttc ggattatgaa agtgaagtag atcctttatt
     4441 tagattttaa ttagatgaac caatatcagc ttggataagg cggtaagcct ttctaagctt
     4501 ttttattgac agtatcagga tatctttttc aaaattttgg tttgttagat aatgaaaatg
     4561 tttctaccga tttagattta ggattaataa gtcgtaaatg taattttaaa gaaaaagata
     4621 agttaaaaaa agatgtatta gcaagagttg gtctaactca tattcatcta gaacaaaaga
     4681 tatatgaatt gtctggcggt gaagcataac gtgttgcttt agcgaaaatc attcttaaaa
     4741 atccaccatt aatactcgcg gatgagctga ctgcatcact cgatccgacg acttcacaag
     4801 gaattatgaa attattatta gatatgaaaa atgaaaatcg tctaatcatc attgcaactc
     4861 ataatcccga tatttggaat caagcagatg aagttataaa tttaaatcaa ttatagttac
     4921 agccaatata tattttctat attttaaagt tattttatct gaatccgtaa aagcagttca
     4981 atcttgtact gacccccaaa agttagacaa ttaatttatc cgaaggattt agttctgtat
     5041 tgcacaggac taagtccttt tagttttatc ttaattcgtt tgttgttgta ataatcaata
     5101 tagtctacaa tagcttgttc caattgatta agcgactgaa atgtcttctc ataaccataa
     5161 aacatttcgg atttcaaaat gccaaagaag gactccatca tgccattgtc tgggctgttt
     5221 cccttgcgtg acatggatgc ttgaattccc ttactctcta ggaaccgatg ataagaatcg
     5281 tgttggtatt gccagccttg atcgctatgg agaatggtat tctcataatg tttctctgta
     5341 aaggcctggt ttaacatagc tttcccttgt tctaagtttg gtgaagttga aagattatag
     5401 gcgataattt cgctgttaaa gccatctaaa actggcgata aatagagctt ttgactgctt
     5461 gctggaatgg caaactctgt cacatccgta tagcactttt ccattggtct cgatgcttcg
     5521 aactggcgtt gaatgagatt ctctgctttc ttgccaatct ctccttggta ggaggaatac
     5581 tttcgtttcc gacgaattcg agctgttaaa ccaagaactt tcatcagacg ttgaactttc
     5641 ttatgattca ccacaaaacc acgatttctt agttcaagag taactctacg atagccataa
     5701 tttcctttgt gctcagtaaa aatagcttga atttcagctt taagatcttt atctttgtca
     5761 agcccaccta gtcccttcaa ctgatagtag taagtcgagc gagctaaacg tgctgtttca
     5821 agaagtaaat ctaattgaaa tcctcctgaa gccatttctc taactatctc tgcctttctc
     5881 gctctagggc ttcgtccctg tcttccagct cttttaactt ttttaagtaa gccacctcgg
     5941 tacgtaagcg ttcattctcc tcttgaagtc gctctagttc tgtcatttct tcccaagttt
     6001 tcttacgttt acgtcccatt ttaggtactc tctctcttgt tttctcaaca atagtatacc
     6061 cgtttttctt gtattgcgcc agccaatttg gaagcatacc acgatttggg agagcatatt
     6121 tgagagaaac tctatcttga gaccagtttt catgtaaaac tttatcaatc atttcttgtt
     6181 ttagttctgg agaatagtat cgatttttcc cttttttgat gaactctatt ccgtaacgat
     6241 caatcaattt aatcatgtac ctaagattag aattgtttat ctcaaattta tttgaaatct
     6301 tctctaagct atatccttgc tttcttagtt catagatctg aactttatcc tcataactca
     6361 atttcataat aaaacacccc aaaaagtaga ttttttctgt ctaacttttg gggtgcagtt
     6421 catcttgtac tgcttttttc ttttacgact tacgctgttt ggcttcatga gcaagccctc
     6481 aaagtgaact aataacaaat catgagaagt caaagtgatg aaatttctgt aacagaagta
     6541 gagcgaattg ctgaaccatt aaatgagtat atctcgaagt agaagcgtct attttgactt
     6601 ttagtctgat agaatggtag tttgaaaatg taaatgatag ctactgttca taaaacataa
     6661 aaggtaagta cggtgttgtg agaagagcta gaaattagca cttacctgat tattccaata
     6721 acctcaaaga tgtgataaaa atttcaacta ctcttatcta taataaagct acctgttctt
     6781 tgaaaattga attcactccg tcttgattag cgtgcctgtg taagtaggga ctgagagtat
     6841 ttccctgtga agggcaactg gcacaagacg tgtgtgagaa ttttctaaca gacacggagt
     6901 ttatcgtttc cagactcaaa cgatgcgaca aactagataa aggagttaat catgaaggta
     6961 gtaaacttgt atgatttgaa acaaatggga aataaaggtg gttgtaccat ccaattgatt
     7021 catcactttc cttttggtat gggcttagga catctcaaaa aagactacat tgaatttaaa
     7081 cgtgttggta tctttgatgg gaaagcagta gaagttactc ttcgagaacc ttattcgaga
     7141 gatctacttc aggttgtcaa gtcaataaag taactgacac cacgagtata attattagaa
     7201 acgtggaatc ttattaaatt ttataataaa tatattaaat gaaaaattat tagatataaa
     7261 cttatgtaat aaaacattga ggaaataata aaaatctatg ggtaatgttc tgaaagtact
     7321 tttaggttag gagagaaata taatgatttt tgaaaattga ttcaaaaaat agcgaattgt
     7381 agaaaacgct taacaaatgg tgtataatag acttccagcg aaacaaaata tgctacaata
     7441 aacctatgaa ttataaagca accttatact catctgtctt cacaaagcat tctagtccat
     7501 ctccgattaa cgatggactt tatcatctcc ttctccagtc cttgtatgac atcttccaaa
     7561 gttcgaaagg ctttattctt aaatccacgt ttacgaatct ctttccacac ttattcaatg
     7621 gggttcatct ctggtgtgta tggaggaata aatgcaaagc caatattagt cggaatcttt
     7681 aaggcacttg atttatgcca tatagcattg tccataacga gtaaaatata atcatctgga
     7741 taagcttgtg aaag
//
LOCUS       DAVLDI010000077         7547 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLDI010000077 DAVLDI010000000
VERSION     DAVLDI010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7547
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.078"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(148..1698)
                     /locus_tag="VXD01_002045"
     CDS             complement(148..1698)
                     /locus_tag="VXD01_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV0602377.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHMIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(1714..2493)
                     /locus_tag="VXD01_002046"
     CDS             complement(1714..2493)
                     /locus_tag="VXD01_002046"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV0602378.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAIQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(2480..3331)
                     /gene="ylqF"
                     /locus_tag="VXD01_002047"
     CDS             complement(2480..3331)
                     /gene="ylqF"
                     /locus_tag="VXD01_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV0602379.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEPSVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(3412..4920)
                     /locus_tag="VXD01_002048"
     CDS             complement(3412..4920)
                     /locus_tag="VXD01_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV0602380.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTDKWRTVTVSYTRNTSRAR
                     KQAEREVMDKIEKLTSSLESQYNPEMITTFGELKESWFQTWCVSVKPQTIKREELVIE
                     RLGKIIGDEFLLDRITPLLMKNCLNKYLDKYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KYSPMTAVKIDVPLEKKREARKRLDAKFLEIHELQAFFDVLGQCRNASYYDLAIVLLL
                     TGIRIGEAAFLPSDVDFDKGILHIDKALQYHDLKVDEFYFDTTKTVNADREVALPIAA
                     SEAIQRAIKRNQEFEAYMEQNPSPAFKKCDSVFQTEYGSPITSHSFRQVLKRVEEKLL
                     KNCQKDYGFKWVKHVTPHSFRHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     ISRSQENTVTALNQFVEKHNFHFKELKSYTCKYSRMIEQFIETCDDNNKVELSVDEFK
                     DLLHLGSRYSPKHIVSNLLLKIKKDIVKYHPQFDIKIVKLSGNQIKGFSISW"
     gene            complement(4996..5229)
                     /locus_tag="VXD01_002049"
     CDS             complement(4996..5229)
                     /locus_tag="VXD01_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0602381.1"
                     /translation="MEIKYVSVENSVAEWADKKSILKRWEGLNLYTLNRWIKEMRENK
                     RFSLYVINPTHKLVFINLEGFECFLRWKQKRTK"
     gene            complement(5531..5754)
                     /locus_tag="VXD01_002050"
                     /pseudo
     CDS             complement(5531..5754)
                     /locus_tag="VXD01_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(6011..6484)
                     /gene="tnpA"
                     /locus_tag="VXD01_002051"
     CDS             complement(6011..6484)
                     /gene="tnpA"
                     /locus_tag="VXD01_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HEV0602382.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVLSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            complement(6642..7442)
                     /locus_tag="VXD01_002052"
     CDS             complement(6642..7442)
                     /locus_tag="VXD01_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0602383.1"
                     /translation="MKADQLRHKSDLGLRGLAIIAKNEIIAFFRSKGLIISQFLQPIL
                     YVVFIIIGLNSSIKNIQFNDIKTSYAEYTIIGVIALLIIGQMTQVIYRVTIDKKYGLL
                     ALKLCSGVRPLYYILGMSIYSILGLIVQEIIIYIITLAFEINIAMDRFFYTVLLSIVV
                     LLFWDSLAILLTMFINDYRRRDIVIRFVLTPLGFTAPVFYLIDSAPSIVRWIGQLNPL
                     TYQLTILRNFYFKNSTTLELVFLLLTSLLVLISVSFIIPKIKLILIER"
BASE COUNT         2306 a         1518 c         1289 g         2434 t
ORIGIN      
        1 aattatagtc ttatttttaa taaagttcaa ttatttatat gtaaaattcc tcatcagtaa
       61 aaaataaccg atctcatttc tgagaatcgg ttttctaaat aaatcaagcc aatcatttac
      121 ataatataaa ttatgtaaat gattgtacta caacaacaaa tctttgactt ttccaatttc
      181 actttttgga ataaccaggt gaatcatatc acccagatac attctggttg agccgttaac
      241 tgtttggctc ttgccattat ggacttgagt tgtgatgagg acgttgtgtg gtaagttgag
      301 ttcatgaact tgtttcccag caattttatc agaaactggt atttcgataa gtgtaacttc
      361 tccttcgcta gatacttctt ctggaagcat tttttccagc atggcttcat agactggcgt
      421 acctttgagc aaatccatga taatataaga aacaagagtg acaagaccaa gtggcatgag
      481 gttgcgaata tctcctacca tctcagttac gaggatcata gcggttaagg gagcttttga
      541 tatggctcca aaatagccac tcattcctag aatgacaaat atagggaatt gctcttgact
      601 gacaagtcca agattgacac agataacacc aattaaggca ccaagcaaag aaccaagagc
      661 taaaatgggg aggaaaattc ctcctggcag tccacttcca tagctaatca tactccaaat
      721 aaagcggatc aaaaagtaag ctaataaaac ttggaaacta aaattttgtt cagttaaaga
      781 aaggacaagc tgatttccgc caccaatgat ttgaggtaag aagattccga ctggtatgat
      841 aaggataaaa gccaagatgg gataataagc tctatccaaa tggatttttt gaccaatcaa
      901 gtcataaact cttccaacgt ttaatacagc tttctcatag agaaagcctg aaaatccaag
      961 gaaaattccc atgacgagat atatccaata ctgatctagg gtcatgggag gaatgttatc
     1021 tggcatatcc aatactggtg tcaaaccgaa catgagtaga gacacaaagt ttgctacgat
     1081 gctggctgct agagttgaga cccagaaaaa gcgcgaaaaa tggtgataga cttcttctac
     1141 aacaaagaga agtgctgcaa taggagcatt aaaggctgcg gctaaacctg ctgcagctcc
     1201 actggcaatc aaggaacgtt cctctactgg actggatttg agccacttgg caattccttt
     1261 accaccaact gctccaagtt gaatactggg tccctctcga cccagcatga gtccactggc
     1321 aatagcgaga atacctagca catatttttt ccaaagaatg ccccaccagt tgagggacat
     1381 gaggcctttc agttcggctt cgacttgagg aattcctgag cctttaatat ctttttctga
     1441 ccgtgttagt ttggcactga gccaacagat gagtatataa aacaaaacca gtacaaaaag
     1501 attgcgcact aagtaccctt gatcttgata aactccttgt atcatgtgga agcccttttc
     1561 aattaagaaa cgaaaggatc cgacgataat tccaacgatg aggccgacaa tgattcctcg
     1621 accaacttgg gatagtatag tgctggatgc aaaggcgaat tctttcttag aacggactat
     1681 ttccgactgt tcctccatgg tatttccttt caattaactt tcttttttac ctaaaaccag
     1741 tgatttaacg ggttcaaagc tggttcggtg aattggggta actcctagtt ttgtgaggcc
     1801 ttccagatgt ttagctgtgc catatcctgc attagtagcg aaatcatagc cagggaactg
     1861 ctgatcgtat tctttcatca attcatcacg tgttaccttg gctactatag atgctgctgc
     1921 gatagagagg gagttggcat ctcctttgat aatggaggtt tgtgaaatgg gcaagtccag
     1981 tttcatggca tcaatcaaaa ggtgctctgg ttgagggctg agctgggaga ttgcttcttg
     2041 catggctagt ttggttgctt catagatgtt gacttggtcg atgacctgat tatctatgat
     2101 accaattcca atcgacaagg cttggtcttg aatggcttgg aaaatctcca gatgtttctt
     2161 tttaggaatt ttcttgctgt cgttgagacc tttaatctta caatttttag gtaaaataac
     2221 ggcagcagcg actacaggac cagcaagagg accacgacca acctcatcaa tacctgcaat
     2281 taaggtcaat ccttgcttat aaagttcttt ttcataagaa agcatggatt ccaagcgcaa
     2341 attttcatct aattcagctt ggatggctct tttacgcttg ctgatttcct tttgaactcc
     2401 tgagcgatta tccttttcaa gctctaaaaa aatagggctt tctaactctt tgactgtcac
     2461 aaggagttct ttgatttctt taatcgttgc catcgaggtc ttccaatgta tctaaggtat
     2521 agttaccgag tttgccatca cggacttcct tcacgaagag actgtaaaaa cggtcatagt
     2581 catcacggaa accgagggcg cgggtcatat ccataataat cacagacggt tcttcttcaa
     2641 ttttcatttg tttgaagcgt tcagccagct tttctggata atgttctttg aaataattga
     2701 taccaaaaat ggtaacctca tccataggaa gcaactggtc tttgatagct ccagtcaatg
     2761 ccaacttaag tgcaacagtt tcatcctcaa acttaggcca gagaatcccc ggtgtatcca
     2821 agatttccag gtctttattg gttttaagcc attgttgacc ttttgtgacc cctggcttgt
     2881 ttccaacaac agcaatcttt ttaccagcca aacggttcat cagagttgat ttaccagcgt
     2941 ttggaatccc gataatcatg gtacgcaagg tttcaatctg aatcccacgt tctttctggc
     3001 gagcaatctt atcagccatg agcttcttgg ccgcatctgt tacaactttt acagtcactt
     3061 gctctttgga gttgatagct agcgtctgga ttccttgtga ttcaaaatac tgacgccatt
     3121 ccttggtcat tgctggatca gccaagtcgg ccttgtttaa aatcaagagt tttggtttat
     3181 caccaacaat cttggtcaac ataggatttt gactagatag aggcaagcgt gcatctacta
     3241 aaatcgtcac aaaatcaaca aattttaaat tctcctgcac ctgtcgacga gctttagaca
     3301 tgtgaccagg aaaccattga atagtagcca ttgagttttt tcctttcgta gcaagggttt
     3361 agcacccctc atttatttta ctatcgtcta aacaccaagc gaacaccaaa actaccacga
     3421 aatggaaaaa cctttgattt gattcccgct taatttcaca atctttatat caaactgtgg
     3481 gtgatatttg acaatatctt ttttgatttt tagcagtaaa tttgaaacaa tatgtttggg
     3541 tgagtaacgt gaaccaaggt gtaataagtc tttaaattca tcaacactta actctacttt
     3601 attgttatca tcacaagttt caatgaattg ttcaatcatt ctcgaatatt tacaggtgta
     3661 actcttcaat tctttaaagt gaaaattgtg cttttctaca aattgattta aagcagttac
     3721 agtattttct tgtgaacgac tgatgttatg ggtgtagccc atcgtggttt caaaattcgc
     3781 atgaccaact ctagtcataa tatcctttac agctatgtgc atttcattac tttgaagata
     3841 actaatgtgc atatgtctga aagaatgagg ggtcacatgc ttgacccatt taaaaccata
     3901 atccttctga caatttttta acaacttctc ctcaaccctc ttcaaaactt gacgaaatga
     3961 gtgagaagtt atcggagaac catactcagt ttgaaataca ctatcacact ttttgaaagc
     4021 aggactagga ttttgttcca tataggcttc aaattcctga tttcttttta tagctctctg
     4081 gattgcttca ctcgctgcta ttgggagggc tacctctcta tcagcattga cggtcttagt
     4141 cgtatcaaaa taaaattcat caacttttaa atcatgatat tggagagcct tatcaatatg
     4201 taaaatcccc ttatcaaaat caacatctga tggtaaaaaa gcagcctctc caatccgaat
     4261 ccctgtcagt aataatacaa tagcaaggtc ataatagcta gcatttctac actgccctaa
     4321 aacatcaaaa aaggcttgca attcatgaat ttcaagaaat ttagcatcaa gcctttttct
     4381 tgcttctctc tttttctcca gaggcacatc tattttaaca gcggtcattg gagagtactt
     4441 aatgacattg tatagcacac cgtgattaaa tatcttgtta cacgtacttt ttatatgtgt
     4501 cattgttgaa ggtgaagcgt cgtatttatc cagatattta ttaagacaat ttttcatcag
     4561 tagtggtgta attcgatcga gtaaaaattc atcaccgata attttaccaa gccgttctat
     4621 caccaactct tcccttttta ttgtctgggg cttgacagat acgcaccaag tttgaaacca
     4681 actctctttt aactctccaa aagttgtaat catttcagga ttgtactgac tttcaaggga
     4741 agaggtcagt ttttctattt tatccattac ctctctttca gcttgctttc gtgctctact
     4801 agtatttcta gtatagctga cagttactgt tctccactta tcagtaagtg gatctttata
     4861 tttttcaacc acttgataca agggttgtcc ttttgaattt gttttagtta cataatacat
     4921 aatttaattc ctcgaaaaga aataaatcat tgttgtatag aataaataac tactctatat
     4981 tataccatga cttccttatt ttgtccgctt ttgtttccat ctcaaaaagc attcgaatcc
     5041 ctcaagattt ataaacacca gcttatgtgt aggattgatg acgtataaag aaaatctctt
     5101 attttctctc atttctttga tccatctgtt aagagtgtag agattcaaac cttcccatcg
     5161 tttcagtatg cttttcttat ccgcccactc agctaccgaa ttttcaacag atacgtattt
     5221 tatctccata ttatcatcct ttcgaataat ttcttctccc tccatggcat gactgatggg
     5281 gtcatcataa gaatctcact tactgctctt ttacgacggc agcctgaacg ttcagaagta
     5341 tcattgtata tcatttgcat catggcagat agagtatcgc tctattttat tggtgattgt
     5401 ccccgctcct atcttggcga atcaagcaaa actgctccac aaatgaggaa agtaccattt
     5461 taggctattc agttgtcaaa gggcaaataa aaaatctcac tcattttcaa actctatgaa
     5521 attgaggaga ttattttcta aagcgaattt tatcaggaaa atcacagtta atcccaataa
     5581 atagtctgta ctgacgtcat agaaatctga gagtttaacc aatacatcag ccgtcaacgc
     5641 atgctcaccc cgttcaattt tggcataagc tgaatttgta aacgaaagta ttgtagctat
     5701 ttgcttttgg ggcagatcat gatcctccct caaatctctc aaacgtctgt acatctagct
     5761 ttctcctaag aaaaagtata gaccatatat tgtaactatt taggatattg tccaaatcgg
     5821 acaacaggaa ttttaccatc ctttatatag acttttattt ttatgtatca agttttttaa
     5881 atcaaaacca ccagtgtgaa ctggtggttt gttctgcggc tataagccgc ttctaccggc
     5941 cagggccaaa ggcccatcga aatagcttcc tcgcgcacca ctttcccgag caggtgctaa
     6001 agcaccttag ttacttcctc ttatttattt cgccagtaaa cggatctact gactcgaata
     6061 acgtgagctg gtctgctact ctgtcttctt gtaattgatt ctgaatatat tcagctatca
     6121 ctttctgatt acggcctacc gtatctacat aatagcctct acaccaaaac ttgcgattgc
     6181 catatttgta ttttaaattc gcatgcttat caaaaatcat caaactgctc ttgcccttta
     6241 aatagcccat aaaggacaaa acactaagtt tcggaggaat actgataagc atgtgaatat
     6301 ggtctgaaca agcattcgct tcatggatta ttacaccctt acgctcacat aagtcacgta
     6361 tgattcttcc gatactagct ttgtatctgc cataaatgat ttgacgacga tatttgggtg
     6421 caaaaacaat atgatattta caattccatg tggtatgtga taaactttga ttatcctctc
     6481 tcatgaggta cctcctgtat gatatgttgt agtggcggag aaaccacttc tatcttatca
     6541 ttttaggagg ttctttttgt taccacgcta aaagctctat ggaaccacta gcatagctag
     6601 tggttttcgg gagacaacaa aaaagttgga tgacccaact tttatctttc tatcagtatc
     6661 aattttatct ttggtataat aaaagataca gatataagga caagtaatga tgttaacaat
     6721 aagaaaacta attccaaagt tgttgaattt ttaaaataaa agtttctcaa aatagttaat
     6781 tgataagtta agggatttaa ctgaccaatc catctcacaa tactaggagc agaatctatt
     6841 aagtagaaaa caggagctgt aaaaccaagc ggtgttagta caaaacgtat tacaatatca
     6901 cgtcttctgt aatcattgat aaacattgta agtaaaattg caagggagtc ccaaaataat
     6961 aaaacaacaa tagataacaa aactgtataa aaaaatctat ccattgcgat atttatctca
     7021 aacgctaacg taattatata tataataatt tcttgaacta tcaaccctaa tatagaatag
     7081 atactcatcc ctaaaatata atataaagga cgaactccac tgcataactt aagagcaagt
     7141 agcccatatt ttttatctat tgtcacccta taaataactt gagtcatctg cccgattatc
     7201 aataaagcta taacaccaat gattgtatat tctgcataag aggtttttat atcattaaac
     7261 tgaatgttct ttatcgaaga atttaatcct attattataa aaacaacata taagattggt
     7321 tgtagaaact gagaaataat taaaccttta cttctaaaaa aagcaataat ctcattttta
     7381 gcaataatcg ctagacctct taaacctaag tccgatttgt gccttaattg atcagccttc
     7441 atttttctcc tcctattctt tgcaaataac tttcttgtaa ggttaattta cttgttgaaa
     7501 agtttttaat ttcacatgct tttcctacct cattgataac atctaag
//
LOCUS       DAVLDI010000078         7240 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLDI010000078 DAVLDI010000000
VERSION     DAVLDI010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7240
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.079"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            70..1329
                     /locus_tag="VXD01_002053"
     CDS             70..1329
                     /locus_tag="VXD01_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV0602384.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHIHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1405..1540
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1579..2079
                     /locus_tag="VXD01_002054"
     CDS             1579..2079
                     /locus_tag="VXD01_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV0602385.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2155..2523
                     /gene="rplL"
                     /locus_tag="VXD01_002055"
     CDS             2155..2523
                     /gene="rplL"
                     /locus_tag="VXD01_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV0602386.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2710..2880
                     /locus_tag="VXD01_002056"
     CDS             2710..2880
                     /locus_tag="VXD01_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602387.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2880..3128
                     /locus_tag="VXD01_002057"
                     /pseudo
     CDS             2880..3128
                     /locus_tag="VXD01_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3142..3482
                     /locus_tag="VXD01_002058"
                     /pseudo
     CDS             3142..3482
                     /locus_tag="VXD01_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3475..3855
                     /locus_tag="VXD01_002059"
     CDS             3475..3855
                     /locus_tag="VXD01_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV0602388.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3868..4011
                     /locus_tag="VXD01_002060"
     CDS             3868..4011
                     /locus_tag="VXD01_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602389.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            4104..4691
                     /locus_tag="VXD01_002061"
     CDS             4104..4691
                     /locus_tag="VXD01_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0602390.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            4893..5030
                     /locus_tag="VXD01_002062"
     CDS             4893..5030
                     /locus_tag="VXD01_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV0602391.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            5320..6723
                     /locus_tag="VXD01_002063"
     CDS             5320..6723
                     /locus_tag="VXD01_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEV0602392.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            6912..>7240
                     /locus_tag="VXD01_002064"
     CDS             6912..>7240
                     /locus_tag="VXD01_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602393.1"
                     /translation="MKDVVYSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLIN
                     GSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVL
                     KKVNLYE"
BASE COUNT         2393 a         1122 c         1505 g         2220 t
ORIGIN      
        1 acctacggca aagtgaatct gaagtggttt gaagagagta caacttgtct tttagaaaag
       61 gagcctataa tgaaagtctt tcagcatgta aatatcgtga cttgtgatca agatttccat
      121 gtttatcttg atggaatctt agcagtcaag gattctcaaa tcgtctatgt cggtcaagat
      181 aagccagcgt ttttagagca agctgagcag attatagact atcagggagc ttggattatg
      241 cctggtttgg tcaattgtca catccattct gcaatgacag gtctgagagg gatccgagat
      301 gacagcaatc tccatgaatg gctcaatgac tatatttggc cagcagaatc tgagtttact
      361 cccgacatga ctaccaatgc ggtcaaagaa gccctgacag agatgctcca gtcaggaaca
      421 acaaccttta acgatatgta taatcccaat ggtgtggata tccagcaaat ttatcaggtg
      481 gtgaaaactt ccaagatgcg ttgttatttt tctccgactc tcttttcttc agagacagaa
      541 acaactgctg agactataag tagaactcga tccatcatag acgaaatctt aaaatataaa
      601 aatccaaatt tcaaggttat ggtagcacct cattctccgt atagctgcag tagagacttg
      661 ctggaagcga gtttggaaat ggcaaaagag ctaaatattc cgctccatgt ccatgtggcg
      721 gagaccaagg aggagtcagg aattatcctc aaacgatacg gcaaacgccc ccttgctttt
      781 cttgaagaac tgggttattt agatcatccg tccgtatttg ctcacggggt cgaattaaac
      841 gagagagaaa ttgaacgctt ggcatcttct caagtggcta tcgcccacaa tcctatcagt
      901 aacctcaaac tggcatcagg aattgctcca attatccagc tccaaaaagc gggagtagca
      961 gtcggaattg cgactgactc ggttgcttcc aataacaatc tagatatgtt tgaggaagga
     1021 aggactgcag ctcttcttca gaagatgaaa agtggggatg ccagccagtt tccaatcgaa
     1081 acagctctca aggtactgac aatcgaaggg gctaaggtcc ttggaatgga aaatcagata
     1141 ggaagtctgg aagtcggcaa gcaagcagat tttctggtca ttcaaccaca agggaaaatt
     1201 catctccaac ctcaggaaaa tatgctgtct cacctggttt atgcagttaa atctagtgat
     1261 gtagatgatg tttatatcgc cggagaacag gttgttaagc aaggtcaagt cctgacagta
     1321 gaactttaaa agaaaaatta cgaaaaattt taaaaaaagt ttgcaaaaat cttgcattct
     1381 ttttttgact atgctatact tatatacggt ttaaaaaaac tgcctaagac agtaggggag
     1441 ctcgactcat aaatatccta ccgaggacaa aacgtatcat gtaaaaagaa gcgtattgta
     1501 ctttcgtgtc taggtttggg cgcgtttttc tttttgaaaa attccccaag caaaataatt
     1561 acggaggtga acacactaat gagtgaagca attattgcta aaaaagcgga actagttgac
     1621 gtagtagctg aaaaaatgaa agctgctgca tctatcgtcg ttgtagacgc tcgtggtttg
     1681 acagttgagc aagatacagt tcttcgtcgt gagcttcgtg gaagcgaagt tgagtataaa
     1741 gttattaaaa actcaatctt gcgtcgtgca gctgaaaaag ctggtcttga agatcttgca
     1801 tctgtatttg ttggaccatc tgcagtagca ttttctaatg aagatgttat cgcaccagcg
     1861 aaaatcttga acgacttttc taaaaacgct gaagcacttg aaattaaagg tggtgcaatc
     1921 gaaggcgctg tcgcatctaa agaagagatt cttgcacttg caactcttcc aaaccgcgaa
     1981 ggacttcttt ctatgctcct ttctgtactt caagcgccag tgcgcaacgt tgctcttgca
     2041 gtcaaagcgg ttgcagaaag caaagaagac gcggcttaat cttaagctat acagcgtagc
     2101 ctagctacga aaaaaactat tataaaattt aaaacttatt tggaggaaat aacaatggca
     2161 ttgaacattg aaaacattat tgctgaaatt aaagaagctt caatccttga attgaacgac
     2221 cttgtaaaag ctatcgaaga agaatttggt gtaactgcag ctgctcctgt agctgttgct
     2281 gcagctgatg cagctgatgc tggtgctgct aaagattcat tcgacgttga attgacatct
     2341 gcaggcgaca aaaaagttgg cgttatcaaa gttgtacgtg aaatcactgg tcttggtctt
     2401 aaagaagcta aagaacttgt tgacggtgca ccagcacttg ttaaagaagg cgttgcaact
     2461 gcagaagctg aagaaatcaa agctaaattg gaagaagctg gagcttcagt tactcttaaa
     2521 taatagagta tcgcaatttg attgcggaat ccctatttac cagtctttga gagcgataag
     2581 cgattgatag aaactgataa attgatttgg tttcctgcca aaaattcttt ggcaggattt
     2641 ttgttttaat aaactttcgg gggtagacac tagattgtct accccttttt ttgtgtttcg
     2701 gaggtaatta tgcaaaagga aggacagtca tcacgtcaat tcgtgaagag tcatctcatg
     2761 actatcatgg gagttgatat tgtaaaagca actcagttag ttgatgaaat ggaacaagta
     2821 ggtttaatcc gatttgatga atttggaaat gttggaattt tagtcttgga gggacaataa
     2881 tgaagcgtat taccgctaat caatatcaga catcagagcg ttattataag ctccccaaac
     2941 ttttatttga gagtgaacgg tataagaata tgaaactgga ggttaaggtg gtttactcag
     3001 ttttaaaaga tcggttggag ttgtctttga gcaaaggttg gattgatgag gatggggcta
     3061 tttatttgat ttattccaat tcaaatttga tggcactttt aggctgttca aagtcaaaat
     3121 tactctccat gtgagtttga agtgacattt ttagatgatt accataaaaa acataactac
     3181 ccactatttt acgaatccta tcttcaaaac gttatggaat tccttgaaag tcaagacata
     3241 aagaatgggg ttgatgcctt tgtagatgat catcaaaatc tcgtttttgt tttatatgga
     3301 caaggctatc gagccgaggg aaaagaggga atacttacaa cccaagtaac tgtaaaagct
     3361 tatgatgaag acaagaaacc gattaacttc gcaaatttat tagattcctt aatttattag
     3421 attccttaat cgtgtcagaa tatcaaatgg aaccgaatct ttgggaggtc tcccatgatt
     3481 gatctctatc taagtaaaaa tagacaaaga aatcaacttc ttttagattt cttccaaaac
     3541 tatggcatag aggtatcttg tcattcagtt tctgaaatga caaaggacaa attaattgag
     3601 atgatgagct attcttcaga ttgttttgag tttttatctc ccaatttatt acgatttaag
     3661 aaccgtgaca atctaagatt aacggatttc gttgagataa ttttaaaaaa tcctgaacta
     3721 accatcagac ttcctcttgc ggtttcaaat aagcgagttt atccaagtct gaatttggaa
     3781 gaggctagag ctctattgcc aagagatacg aaacaattga tttacatggc gcaaacacat
     3841 tatttatcta actaaaggag aagcaatatg gctgaacgat tttgggagaa cttgtccatt
     3901 attttggctg aaagaaatat cagctggatt gagttaacca gaaaaatgtt tgcgggagag
     3961 tttcactatc caagtgaatt gaatcgtttg tatcaaaaga ttcgccacta gaagatggaa
     4021 caatgaatgc ctcaaagtcc atgggtagaa aggattgtgc aggtattaga tttagattat
     4081 gaagatttat ttcggaggta actatgaaaa gaataattcc agtttatata ttccaacaag
     4141 taaatgtcct attggtatct ctatacttat tgaaatttct ttgtatcggt gagttaacta
     4201 tactacagat tctctatggt tcgtcactca tttctttttt atggatgtat ggccaacgca
     4261 aacaagctca taaggtaaat atgaaatcta ggatgaaatg gcttggtatt ggattcgtta
     4321 gcctactgat tataagtcta tgttttagcc taatccatgc gcaagaaagc acgaatcaag
     4381 caaacttaat tggacttcaa catcaagttc cttggttttc atttttattg tttttaatca
     4441 atgcgagtat ggttgaagaa tttctgtata gagaaatttt atggaacttg gttagaaaat
     4501 tagatattcg agttgctttg acaagtgttt tatttgcctt agcacatcat ccaggaacca
     4561 ttatagcttg gtgtttgtat gtatcgctgg ggatgttttt agggcttgta cgctacaaat
     4621 tggacttatg gggcagtatg gggctacatt tggtgtggag cctactagtt tatagtttgc
     4681 tgctttttta aaataggtaa cctgattttt aggtaacttc taaaactaac ttccagtttt
     4741 gggagagaga tggaagttac tttgaaaagt tacggaaaca ttattttcta cgtgacaaca
     4801 ttgtatcatt gcttgcattt tactgctgga gagagtataa tgaaggtgga taaagcactt
     4861 aatcccaaaa atttaaatag gaggagttag ctatggcaga agaagtatta aatcttcaat
     4921 tagtatctgt tcaagttgac gaaacagatg aagttgatgg aatgcgattt agtacattca
     4981 gtacaaaccg ttgcggtaac tggagtgctt ttagttggga aaattgttaa ttcatttaaa
     5041 ttgtaaactt tagggattct ctggagttat ggatctcgtt ccaatatgtg cacgttggaa
     5101 tgtcagtgct tatatggggg gaatccaaag gattctccct ttttatttta ataagtctgt
     5161 ctagctatag atatattaag tttgatagaa tttcttggag attttgttat ggattataat
     5221 ttcaatttgg agcatccttt ctttttcact aataatgatt atagtacaga tactagcata
     5281 aagtactaag taagtctgcc ttttaattgg cacgaagtaa tgaataatga tgagtgggtt
     5341 tatcaatacc ctattggaaa atttgttgaa agacaagggt ggaaaataca cattagttca
     5401 gagtataata gttcacacga attgttacaa gatgtagcaa aaatttgcca tgaaatgcga
     5461 attccattta aacatcttag tacagaagac aaatttatca tgcgaaacgg gaaattggtt
     5521 agtcgaggat tttctggtaa atttattaca tgttatccaa atcaaaatga attagagtcg
     5581 gttttgcaaa ggttagaaag tgccttaaag caatataatg ggccatatat tttaagcgat
     5641 aaacgttggg atgaagcacc aatatatctg aggtatggtg tgtttaggcc gtcaagggat
     5701 gatgaaaaga aggttgttat tgatgaatta attgttggcg atgaagttgt taaagatgaa
     5761 cgtttaccag tatttaaaat tccaaaaggt atagtgcccc ctgacttttt gaataaatgg
     5821 cttgacaaga aagataaaaa acagggagac tttcccttta ttatagataa tgcaattaga
     5881 ttttcaaaca gtggtgggat atataatgct agactaaaag aagatgggaa aaaaataatt
     5941 ttaaaagagg ctagaccgta tacaggtcta ggatttgatg gtacttattc ttcagagaga
     6001 ttagcttcgg agtgcaaagc actaaaaatt ctaaatgaat ggagtgagat gcctaaaata
     6061 tactggtacg gtaagatctg ggagcacacc ttcttaggaa ttgaacatat gaagggcgtt
     6121 ccactaaata gatgggttac caataatttt cctttatatg aagttgttga taagaccaaa
     6181 gattatctat tgagagtttc aaagatagta gaaaaactca tcgatttaac gaataagttt
     6241 cattctgaaa atgtatatca tcaagattta catttaggaa atatcttggt taaggatgaa
     6301 gatgagatta gtataataga ctgggaacag gctgtctttt cgaatgatga aaaagttgta
     6361 cataaagttg cagcccctgg ttttagagca tggcgagaaa cacttcccag tgagatagat
     6421 tggtatggta ttagacaaat agctcattat ttatacatgc cactagtaac tacatcggat
     6481 ttgacataca actatgtaag tcaaaccagg atagaaggaa aaaaactatt tgagtctttg
     6541 ggttatacaa gagaacatat agattatgta gaaagtttat tgtcatatct agattctaaa
     6601 tgtccacaga ttgagaatat ttccaggaaa aaagttttaa aacccatgca tgagattaga
     6661 actatcgaga gtgagcaaga tatacaagat tttattataa aagcttttct tttagtgaac
     6721 tgataggtat tttcttagca aacgataaag ttttagggcc gatacaatca attgcctatt
     6781 cattaaataa gataaataca accaaagatt taaggaaacc gtttttaaaa tacttaagtg
     6841 gagagaagaa ttttgtagac gctgaacatg ataataacgg actgtatact tcatcaatag
     6901 atgagataca catgaaagat gttgtatatt ctattacacc agaaaataaa ttaagtattg
     6961 acttctcatt taagtcacca tttagggtat tattaacagg aacttctggc agtgggaaaa
     7021 caacgatttt aaatttaatt aatggttctt taaagccaca aaaaggttat gtaaatttgt
     7081 tatcacatgg gaaaaagagt tcagattcaa taccaacagt tgatcagaca ccatatattt
     7141 ttgacactac tattcgtgag aacgtaactt tatttcaaaa tgaatatttt tcagatgatc
     7201 agataattga ggtgttaaaa aaggtaaatc tatatgaaga
//
LOCUS       DAVLDI010000079         6904 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLDI010000079 DAVLDI010000000
VERSION     DAVLDI010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6904
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.080"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..483
                     /locus_tag="VXD01_002065"
                     /pseudo
     CDS             1..483
                     /locus_tag="VXD01_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            569..1519
                     /locus_tag="VXD01_002066"
     CDS             569..1519
                     /locus_tag="VXD01_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0602394.1"
                     /translation="MGKKRWARNGSESNDASYAQVVSLYDDTSISVSNNETDKVLTGS
                     LYTETNEQGLTIPSSLLKNWNEQTGKNLTTNDLIGKSVSASIVESAAETSKIAQFQTK
                     IVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQK
                     NKKYTVFSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIG
                     VMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFE
                     LNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1696..2703
                     /gene="gap"
                     /locus_tag="VXD01_002067"
     CDS             1696..2703
                     /gene="gap"
                     /locus_tag="VXD01_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV0602395.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2770..3606)
                     /locus_tag="VXD01_002068"
     CDS             complement(2770..3606)
                     /locus_tag="VXD01_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV0602396.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3732..5927
                     /locus_tag="VXD01_002069"
     CDS             3732..5927
                     /locus_tag="VXD01_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV0602397.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMASQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQVVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5980..6132
                     /gene="rpmG"
                     /locus_tag="VXD01_002070"
     CDS             5980..6132
                     /gene="rpmG"
                     /locus_tag="VXD01_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV0602398.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6142..6318
                     /gene="secE"
                     /locus_tag="VXD01_002071"
     CDS             6142..6318
                     /gene="secE"
                     /locus_tag="VXD01_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV0602399.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6373..>6904
                     /gene="nusG"
                     /locus_tag="VXD01_002072"
     CDS             6373..>6904
                     /gene="nusG"
                     /locus_tag="VXD01_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV0602400.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2148 a         1207 c         1495 g         2054 t
ORIGIN      
        1 aattttaata gtttaaagca cctagcacct gtttagattg atgaaacagg attcgatact
       61 tatttttatc gagaatatgg tcgctcatta aaaggtcagt taagaagagg taaagtatct
      121 ggaagaagat atcagaggat ttctttggtt gcaggtctaa caaatggtga gttaatcgct
      181 ccaatgactt acgaagagat gatgacgagc gacttttttg aagcttggtt tcagaagttt
      241 ctcttaccaa cattaaccac accatcggtt attattatgg ataatgcaag attccataga
      301 atgggtaagt tagaactttt atgcgaggag tttgggcata aacttttacc tcttcctccc
      361 tactcacctg agtacaatcc tattgagaaa acatgggctc atatcaaaaa gcacctcaaa
      421 aaggtattac caagttgcaa taccttttat gaggctcttt tgtcctgctc ttgtttcaat
      481 tgactatagt tcacggatac agttgggaaa gaagctatta aatatttgga gagtcctttt
      541 gggatgaaca tgtcaaatat tactatagat gggcaagaaa agatgggcaa gaaatggatc
      601 tgagtcaaac gatgcttctt atgctcaagt agtgagtctt tatgatgata caagtatctc
      661 tgttagtaat aatgagacgg acaaagtgtt gactggatcc ctctatactg aaacaaatga
      721 acagggatta acgattccaa gcagtttact aaaaaattgg aatgaacaga caggaaaaaa
      781 tttgacaact aatgatctta ttggcaaatc agtctcagcc agcattgtag aaagtgctgc
      841 cgaaactagt aagattgctc aatttcaaac gaagattgta cgtgtaatca atgatgaaga
      901 tgacatggag gacagcaaca gtttcatgct gtctcatcaa atggaaacga ttttgaaaga
      961 ggctggattt acgaaagctg tatcttattt tatcttggaa ctcaaagatc catcacagac
     1021 aaaagtagta acagaagaat tacagaaaaa taagaagtat actgtgtttt ctcaacagag
     1081 agttcttgat attgtgatta cctttattcg tgttattcag ggattattga ttgtgctttc
     1141 atcacaagct attgtggtag cagcggttat gattggtatc attatttaca tcaatatcat
     1201 gcaacgttcc aaggaaatag gtgtcatgaa agcagttggt tatcagaatc gtggtgtcaa
     1261 aggaattttt atttacgagg ctatctggat tgtaggcatc gccttgctgc tggcattttt
     1321 ggttgcacaa ggggtgggaa gtttggcgaa tgcgattgta agtcactttt acccatccat
     1381 cactaaggtt tttgaattaa atcttttatc tgttttagga actctagttt tcgctctatt
     1441 acttggttat gtctcagcct acttcccggc gcgtaagatt agtaaaatgg atcctgtaga
     1501 atcgttacgc tatgaataat aagggattcc ttgatttaca gtcttaaaaa gaaactcaca
     1561 tagaaaaaca atggccatac ttgcaattca actcaaatag ttgtataata ggtttgttga
     1621 aaggtgattt gtagtgattc aagttactct tttcacaata aaaatttcat gattttcata
     1681 aggaggaaat cactaatggt agttaaagtt ggtattaacg gtttcggacg tatcggtcgt
     1741 cttgctttcc gtcgtatcca aaacgtagaa ggtgttgaag ttacacgcat caacgacctt
     1801 acagatccag ttatgcttgc acacttgttg aaatacgaca caactcaagg tcgtttcgac
     1861 ggtactgttg aagttaaaga aggtggattc gaagttaacg gtaaattcgt taaagtttct
     1921 gctgaacgtg atccagagca aatcgactgg gctactgacg gtgtagaaat cgttcttgaa
     1981 gctactggtt tctttgctaa gaaagaagca gctgaaaaac accttaaagg tggagctaaa
     2041 aaagttgtta tcactgctcc tggtggaaac gacgttaaaa cagttgtatt caacactaac
     2101 cacgacgttc ttgacggtac tgaaacagtt atctcaggtg cttcatgtac tacaaactgc
     2161 ttggctccaa tggctaaagc tcttcaagat aactttggtg ttgttgaagg attgatgact
     2221 actatccacg cttacactgg tgaccaaatg atccttgacg gaccacaccg tggtggtgac
     2281 cttcgccgtg ctcgcgctgg tgctgcaaac atcgttccta actcaactgg tgctgctaaa
     2341 gctatcggtc ttgtaatccc agaattgaac ggtaaacttg acggatctgc acaacgcgtt
     2401 ccaactccaa ctggatcagt tactgaattg gtagcagttc ttgaaaagaa cgttactgtt
     2461 gatgaagtga acgcagctat gaaagcagct tcaaacgaat catacggtta cacagaagat
     2521 ccaatcgtat cttcagatat cgtaggtatg tcttacggtt cattgtttga cgcaactcaa
     2581 actaaagttc ttgacgttga cggtaaacaa ttggttaaag ttgtatcatg gtacgacaac
     2641 gaaatgtcat acactgcaca acttgttcgt actcttgaat acttcgcaaa aattgctaaa
     2701 taattcttga gttgatagaa agcaaggctt tgtggtcttg ctttttatat ggaaaaatgg
     2761 atgacacgat catccattct tttttaattc tttttcaaat gtatttgaaa gggtagtgaa
     2821 agttagcttc tctaaagtaa gtgggtgggt aaaggaaagt cggaaggcat gaagcataag
     2881 ccgacttgtc tttgatttac tattatagag agggtcgccc aggataggaa gattatgatg
     2941 cgaaaggtgc acacgaatct gatgggttcg ccctgtcttt agcttgcaac gagccaagga
     3001 agtcttgttt gagaattgct ttaacctgct tacatgcgtt tcagcatatt gcccattttt
     3061 tgcatcaact attctttttc tacgatcatg gcgatcacgt ccaattttgt ctctgaaaac
     3121 aagttctttt ctgttgatat ttccatcaac tagagcccaa tattctctag aaatctcttt
     3181 tttctccaat aagcgattga gaatgggcag gataaaagga tttttggcaa agagaactaa
     3241 gccactggtt tccatgtcca gacgatgaac gacatagcag gtttggccaa cataggtact
     3301 gacatggtta agaagggcaa tttcgtttgg ttgattacca tgcgttttca tcccctctgg
     3361 tttgtttaca ataatcaagt gttgatcttg ataaacttcc tgcactaagt ctgggttgcc
     3421 ccaagggatc gtcttttggg aataatcttc ctcgtcaaaa gtcaactggc aaacatctcc
     3481 aggatttacg atttcgttcc agtggacttc ttcttgattt atcaaaatat gtttcttgat
     3541 tctcaaaaaa tgacggattt ttctagggat gaggagttgt tcctcaagta attgctttac
     3601 cgtcatttga ggtagagagg cgggtaatgt aaatgtgaat tgcatacaga tattgtaaca
     3661 aaaaaagccc tatttggata ggaaatagct aaattcttgt cttcctatga tgaagatgat
     3721 aaaataaacg catgaaatta gataaattat ttgagaaatt tctttctctt tttaaaaaag
     3781 aaacaagtga actagaggac tctgattcta ctatcttacg tcgctctcgt agtgatcgaa
     3841 aaaaattagc ccaagtaggt ccgattcgaa aattctggcg tcgttatcat ctaacaaaga
     3901 ttatccttat actaggtttg agtgcaggct tgctagttgg aatctatttg tttgctgtag
     3961 ccaagtcaac caatgtcaat gatttgcaaa atgccttgaa aactcgaact cttatttttg
     4021 accgtgaaga aaaagaggct ggtgccttgt ctggtcaaaa gggaacctat gttgagctga
     4081 ctgacatcag taaaaacttg cagaatgctg ttattgcgac agaagaccgt tctttctata
     4141 aaaatgacgg gattaactat ggccgtttct tcttggctat tgtcactgct ggccgttcag
     4201 gtggtggctc taccattacc caacagctgg ctaaaaacgc ctatttatcg caggatcaaa
     4261 ctgttgagag aaaagcgaaa gaatttttcc ttgccttaga attaagcaaa aaatatagta
     4321 aggagcaaat tctaaccatg taccttaaca acgcttattt tggaaatggt gtgtggggtg
     4381 tagaagatgc gagtaagaaa tactttggag tttctgcatc agaagtgagt ctggatcaag
     4441 ctgcgactct ggcagggatg ctcaaggggc cggaactgta taatcccttg aattccgtag
     4501 aagattctac taatcggcgc gatactgtct tgcagaatat ggttgcagca ggatatattg
     4561 ataaaaacca agaaaccgaa gctgctgaag ttgatatggc ttcgcaattg cacgataagt
     4621 atgaaggaaa aatctcagat taccgttacc cctcttattt tgatgcggtg gttaatgaag
     4681 ctgtttccaa gtataatcta acagaggaag agattgtcaa taatggctac cgcatttaca
     4741 cagagctgga ccaaaactac caagcaaata tgcaggttgt ttatgaaaac acatcgctat
     4801 ttccgagggc agaggatgga acgtttgctc aatcaggaag tgtagctctc gaaccgaaaa
     4861 cagggggagt tcgtggagtt gtcggtcaag ttgctgacaa tgataaaact ggattccgga
     4921 atttcaacta tgcaacccaa tcaaagcgta gtcctggttc tacaattaag cctttagttg
     4981 tttatacgcc agcagttgaa gcaggctggg ctttgaataa gcagttggat aaccatacca
     5041 tgcagtatga cagctataag gttgataact atgcagggat caaaacgagt cgagaagttc
     5101 ctatgtatca agccttggca gaatcgctta atctacctgc tgttgccact gttaatgatt
     5161 tgggtgtcga caaggctttt gaggcaggcg aaaaattcgg actcaacatg gaaaaggtcg
     5221 accgtgttct tggtgtcgcc ttgggaagcg gtgttgaaac caaccctctt caaatggctc
     5281 aagcatacgc cgcctttgca aatgaaggtt taatgcctga agctcatttt attagtagaa
     5341 ttgaaaatgc tagtggacaa gttattgcga gtcataaaaa ttcacaaaaa cgggtgattg
     5401 ataagtctgt agctgacaag atgaccagta tgatgttggg gactttcacc aacggtaccg
     5461 gtattagttc atcgcctgca gactatgtca tggcagggaa aactggaaca actgaagcag
     5521 ttttcaatcc ggagtacaca agtgaccagt gggtaattgg ttatactccg gatgtagtga
     5581 ttagccactg gcttggcttt ccgaccactg atgaaaacca ttatctagct ggctctactt
     5641 caaacggtgc agctcatgtc tttagaaaca ttgccaatac cattttacct tatacgccag
     5701 gaagtacctt tacggttgaa aatgcttata agcaaaatgg aattgcacca gccaatacaa
     5761 aaagacaagt acaaaccaat gataatagcc agacagatga taatttgtct gatattcgag
     5821 ggcgtgcgca aagtctagta gatgaggcta gccgggctat ctcagatgcg aagattaagg
     5881 aaaaggctca aacaatatgg gattcgatag tcaatctatt tcgctaagat gcttgtcaaa
     5941 gcctagcttt cttgttataa tggataagat ggaggcgtta tggcactaaa aaaagcaagc
     6001 ctagcttgtg cggtttgtgg ttcgagaaac tattcaatca agatcagcgg aaaccccaag
     6061 cctacacgac tagaagtaaa taaattttgt aagcattgtg gcaagtacac tacacacaga
     6121 gaaacgagat aggagagagc gatgcgtttt attggagata tttttagact tcttaaagac
     6181 acaacatggc caactcgcaa ggaaagctgg agagattttc gttctatcat ggaatacaca
     6241 gctttctttg tagtaattat ttacattttt gaccagttga ttgtttcagg tttgattcga
     6301 tttattaaca ttttttagaa gattagtgga gttaattaca ctagaaatct tctatttatg
     6361 aaaggaaata tcatggatag ttttgataaa gggtggtttg ttttacaaac ttattctggt
     6421 tatgaaaata aggtgaaaga aaatctatta caacgtgcac aaacctacaa tatgttggat
     6481 aatattctac gcgttgaaat tccaacacaa acagtgcaag ttgaaaaaaa tggaaagaga
     6541 aaagaagtag aagaaaatcg ctttccaggt tatgttcttg tagaaatggt catgacagat
     6601 gaagcttggt ttgttgttcg aaacacacca aatgttacag gatttgtcgg atcacacggg
     6661 aacagatcaa aaccaactcc attattggaa caagaaattc gcgacatttt ggtatctatg
     6721 ggacaaactg ttcaagaatt tgatttcgat gttgagattg gtcaaactgt acgtattatt
     6781 gatggtgctt ttgcagacta cactggtaag attacagaaa ttgataataa caaagtgaaa
     6841 atgattatct ctatgtttgg taatgacaca gttgcagaag taaatctaaa ccaaatcgca
     6901 gaat
//
LOCUS       DAVLDI010000080         6407 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLDI010000080 DAVLDI010000000
VERSION     DAVLDI010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6407
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.081"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            124..915
                     /locus_tag="VXD01_002073"
     CDS             124..915
                     /locus_tag="VXD01_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602401.1"
                     /translation="MNFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     IGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTKPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILISSHKL
                     EDIEEICERVLFLESGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            931..1659
                     /locus_tag="VXD01_002074"
     CDS             931..1659
                     /locus_tag="VXD01_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV0602402.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     ETSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            2044..2253
                     /locus_tag="VXD01_002075"
     CDS             2044..2253
                     /locus_tag="VXD01_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0602403.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            2243..2731
                     /locus_tag="VXD01_002076"
     CDS             2243..2731
                     /locus_tag="VXD01_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602404.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            2847..4307
                     /locus_tag="VXD01_002077"
     CDS             2847..4307
                     /locus_tag="VXD01_002077"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV0602405.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEGLRFSDSDIAYLELLGYHGAFLNYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            4304..5128
                     /gene="nadE"
                     /locus_tag="VXD01_002078"
     CDS             4304..5128
                     /gene="nadE"
                     /locus_tag="VXD01_002078"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV0602406.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRSETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            5526..6077
                     /locus_tag="VXD01_002079"
     CDS             5526..6077
                     /locus_tag="VXD01_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0602407.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
BASE COUNT         1999 a         1077 c         1351 g         1980 t
ORIGIN      
        1 agaggcgcaa ctttttaaac tcaataagaa tcaaagagca aaccatgaat attaatggag
       61 gaataaaaaa tgtaagttat aaatgtaagt aagcattatg gtcattcaat cattctcaaa
      121 gatataaatt ttgcacttaa caagggtgaa attgttggtc tagtagggag aaatggagtt
      181 ggtaagagta cgttgatgaa aattcttgtt cagaataatc aaccgacttc aggtaatatt
      241 ataagcagtg ataatattgg gtatttaatc gaagaaccaa aattattttt atctaaaaca
      301 ggtttagaga atttaaaata tttgtcaaat ttatatggtg ttgactacaa tcaagaaaga
      361 tttagaagtt tgatccaaga gttagatttg actcagtcta ttaataaaaa agtaaagacc
      421 tattctttgg gtacaaaaca aaaattagct ttgcttctaa ctctcgttac gaaacctgat
      481 atattgattt tagatgaacc gactaatggt ttagatattg aatcatcaca aatagtttta
      541 gcggttctaa aaaaattagc tttaaatgaa aacgtgggaa ttttaatatc gagtcataaa
      601 ttagaagaca ttgaagaaat ttgtgagagg gttcttttct tggagagcgg gcttttgaca
      661 tttcaaaaag taggaaaaga tagtcataat ttcttgtttg agatagcttt ttcatcagct
      721 acagatagag acattttcat taccaaacaa gaatttgggg atattgttca ggaagaggga
      781 ctgagaatta ctatgtctgg gaatattcaa agtagtgagc tttttaaatt ttttaacgaa
      841 aactctatta aagtagttga ttttgaaact aaaaaagaga cgcttaaaga tatttactta
      901 aatcgttcaa aataaaggaa ggttataatc atgaaattaa ataaattgaa ttttcttaag
      961 gaaaatataa gaaatttata ttcatcaggc gtaatatatc tcagtttgct tatctcgttt
     1021 ataccgccga tattgcttac attctttatt ctaaagactc aagagacatc gcttggtatt
     1081 aagcatattt caaactttta tgctatgctc ggtatgttaa tggctgttat acatgctaat
     1141 cgagttatta gtagagattt ttcccacaat acggtaagtt tgttttataa tcaacagaag
     1201 aatcggatga tttacgtctt gtctaatttt ctatatgcca tctcagtttc cattatttat
     1261 gctttgaatg gcattgtgtt actagtcata gtaagtaaat tgggtattcc aggtgattta
     1321 ggattagatt ttatagtagc tattgtagtc aatacaattt tgttagtcct gttttatttt
     1381 ctattatctt acattttcta tttatacaaa ttgaaaagtg gcttggtatt tggtatttta
     1441 gtagctttac tactctttat ccctaatata ttaaatacga tgatgatgaa tactagtaat
     1501 gatttgttta tcaaagcaat tgaacttctt cctttttatt ctttacctgt atttgtggct
     1561 tcaaatacga tgtctattag tcagtatctt gtggtaatca ctacaatcat tttattgtac
     1621 tttttcactc tcaagaaaag caagaagtat tcattttagt ttcatttagt attattttgc
     1681 atacctaaaa tacagtaaaa aatcagtcat cttggtatgc tcctgctttc actattcaac
     1741 acgtttttga cttatactag gctcatttcc aaaagcatta tataatagtg atatgaaacc
     1801 aactaaacta aacaagaaat ataagcaata aaaattcgtt taaaagatct tactaaagct
     1861 aatactaaat aaaaataaaa gagtaaacta ggaagtttat ttcaaacaac ctaaaatact
     1921 gattttcggc tgaagataat actggaatgc aaattaatgg ggttataata aatagctgat
     1981 agcttgtgtt ggttttggat tttttaagag tagatgagta ttaaaactat aaggaggacg
     2041 aaggtggcta aaaatttaaa attaaaatta gctcgggtag agcgtgattt aacacaaggt
     2101 caactggcag aggctgtcgg ggtgacacgc cagactattg gtttaataga ggcgggaaaa
     2161 tacaatccca gtctctcgct ctgccagtct atttgcagat gtttagggaa aaccctagac
     2221 caactatttt gggaggaaga agatgaaaaa tagattttat tattatcaat tactagacga
     2281 aagagaagaa caactgttca ataaagcggg ctctgaaagt ttctatatct gcattgcttt
     2341 gtcgctccta tcttatatca tttcagtatt agcaccaagc ctttttaatt ctaatatgct
     2401 gctaatcgtt atcatcatag ggacatttta ctttttcaat cgtgcccgtt atctgggagt
     2461 gacctactat agtcgttttc attttacgat tttgggttgt tttttcctaa ccttggctat
     2521 tacggctctt ttgatgttgc agaattatca attcaacata gaaatttatc agcacaatcc
     2581 tttgaatttt aaatacctgt ctgcttgggt cattacttat atcatttacc ttccgtggat
     2641 ctttattggc aatcttggtc ttaagagcta tggcgaatgg gctcagaaaa aatttgaaca
     2701 agatatggat gaattggaga gtggagaata gcttgttact cttttctcaa tccagctaaa
     2761 atgtgatata atagtactaa tttattggaa tacatgaaag ttcttgaaaa ttttcatggg
     2821 tttctagcta aggaagtagg aaaagtatgt atccagatga tagtttgaca ttgcacacgg
     2881 acttgtacca gatcaacatg atgcaggttt actttgacca agggattcac aataagaagg
     2941 cggtctttga ggtgtatttc cgccaacagc cttttaagaa cggctatgcg gtttttgcag
     3001 gtttggaaag aattgtgaac tatcttgaag gcttgcgttt ttcagatagt gatatagcct
     3061 atttggagtt gcttggttat catggggcgt tcttgaatta ccttcgcaat ttcaagttgg
     3121 agttgaccgt tcgttctgcc caagaagggg atttggtttt tgctaatgaa ccgattgtgc
     3181 aggtggaagg acctctagcc caatgtcagt tggtcgaaac ggctcttttg aacatcgtca
     3241 actaccagac cttggtggcg acgaaggcag ctcgtattcg ttcggttatc gaagatgaac
     3301 ccttgatgga gtttgggaca cgtcgggctc aagaaatgga tgcggccatc tggggaacac
     3361 gcgcagcggt gattggtggc gccaatggaa ccagcaacgt gcgtgcgggt aagctctttg
     3421 acattcctgt tttgggaacc catgcccatg ccttggtaca ggtttatggc aatgactatg
     3481 aagctttcaa ggcttacgct gcgacccaca aaaattgtgt ctttcttgtg gatacctatg
     3541 acacccttcg catcggtgta ccagctgcca ttcaggtggc gcgtgagctg ggtgatcaga
     3601 ttaactttat gggtgtgcgg attgactctg gggatattgc ctacatttct aagaaagtcc
     3661 gtcaacaact ggacgaggct ggatttacag aggctaagat ttatgcttct aatgatttgg
     3721 acgaaaatac tatcctcaac ctcaagatgc aaaaggccaa gattgatgtc tggggcgtgg
     3781 gtaccaagct gattacagcc tatgaccagc cagctcttgg tgcagtttac aagattgttg
     3841 caatcgaaga tgaaactggt cagatgcgca atacgattaa gctgtctaat aatgcggaaa
     3901 aagtctctac gccaggtaag aagcaggtgt ggcgcattac cagtcgtgaa aaaggcaagt
     3961 cagaaggcga ctatatcact tatgatggtg tggatattag cgacatgaca gaaatcaaga
     4021 tgttccatcc gacctataca tacatcaaga agacggttcg taattttgat gccgttcctc
     4081 tcttggtgga tatcttcaaa gaaggaatat tagtttacaa cttgcctagt ttgactgaca
     4141 ttcaggatta tgcccgtaag gaatttgaca agttgtggga tgagtataag cgtgtgctca
     4201 atccgcagca ctatccagtg gatttggctc gtgatgtatg gcaagataag atggacttga
     4261 ttgataagat gcgcaaggaa gcccttggtg aaggagaaga agaatgagtt tgcaagaaac
     4321 gattatccaa gagctgggtg tcaaaccagt gattgatgcc caggaagaaa tccgtcgttc
     4381 tattgatttc ttaaaaagat atctgaaaaa acatcccttc ctaaaaacct ttgtactagg
     4441 gatttctggg ggacaagact caaccttggc agggcgtttg gcgcaattag ctatggaaga
     4501 actgcgatct gaaacgggag acgacagcta caaatttatc gctgtccgcc tgccatacgg
     4561 agtgcaagct gatgaagcag atgctcaaaa agctctagcc ttcatccagc cagatgtcag
     4621 cttggttgtg aatatcaagg aatcagctga tgccatgaca gctgcagttg aagcgacagg
     4681 tagtcctgtt tcagacttca acaaggggaa tatcaaggca cgttgccgta tgattgctca
     4741 gtatgccctt gctggttccc atagcggagc ggtcattgga acagaccacg ccgcggaaaa
     4801 tatcacaggt ttctttacca agtttggtga cggcggtgcg gatattctcc ctctttaccg
     4861 cctcaataaa cgccaaggaa aacagctctt gcagaaactt ggcgcagagc cagcccttta
     4921 tgaaaaaatc ccaacggcag acctagaaga agataaacca ggcctagctg acgaagtcgc
     4981 acttggagtc acctacgcag agattgacga ctacctagaa ggcaaaacaa tcagcccaga
     5041 agctcaagcg accattgaaa actggtggca caaaggccaa cacaaacgcc acttacccat
     5101 cactgtattt gatgactttt gggagtaaaa acctccattg gaggttttta ccctgagcct
     5161 agaaatgaga aagcgaagaa ggtccggggg actttttagc ttcttgccct gaaattaaaa
     5221 agcaagaaaa acctccactg gaggttttca gcctctcatc ttgaaataag aaagtgagag
     5281 aaggtctggg ggatcttgaa ccccgagttt agaaataaga aaatgaggca gattcagtaa
     5341 ctcgaagagt tcgatttcat cgtcttaccc ctgcaacgat gactaggttt gaaaaagctt
     5401 gctagagcgc atttcaaacc aggcagcaac tgcgtcaaga aattagaaga caaactcgtt
     5461 ttctagctgt tactgagttg agccttttta ctacgagtat agaaataagg aagtgaggta
     5521 gcatcatgaa atctatcggt acgcaaatat tacagacaga acgtttgatt ttaagaagat
     5581 ttgtggagag tgatgcagaa gccatgtttc aaaattgggc ttcatccgct gagaatctga
     5641 cctatgttac ctgggatccc catcctgatg tcgaaatcac tcgaaactcg atttgcaatt
     5701 gggttgcttc ctatactaat ctcaactatt ataaatgggc catttgtcta aaagaaaacc
     5761 cagagcaagt gataggagat atcagcattg ttaagataga cgaggctgat ttaagctgtg
     5821 aaattggcta tgtgttaggc aaggcttact ggggaaatgg tatgatgaca gagactttga
     5881 aagctatctt ggacttttgt tttactcaag caggttttca aaaggtcaga gcacgttatg
     5941 ccagtctcaa cccagcttca ggtcgtgtca tggaaaaggc tggaatgtcc tatctacaaa
     6001 ccattgttaa tggtgtagag agaaaaggct atcttgcgga tcttatttat tatggtataa
     6061 gtagggaaga atgttgaatt ctattttctg tttctatcga agtcaactat ttattgtaaa
     6121 tataataatt agcattccaa gtttatttga aactttaaaa tagcatattg attagtacaa
     6181 gacagatgtt ctagttcctt ctttaatctg gtttagtgtt agttaaaaaa tcgctttaag
     6241 cttgtaacta agagggagct aatcgactag attctccagc cgaacaggtg gtaatgtact
     6301 ttttatagtg taatcctagc tgttgttaaa tttaaaatag aatcctctat cgagttaggg
     6361 aattaaattc aaccaatttt attcatgttt tttctatcaa attatct
//
LOCUS       DAVLDI010000081         6377 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLDI010000081 DAVLDI010000000
VERSION     DAVLDI010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6377
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.082"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(807..2057)
                     /gene="ilvA"
                     /locus_tag="VXD01_002080"
     CDS             complement(807..2057)
                     /gene="ilvA"
                     /locus_tag="VXD01_002080"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV0602408.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(2107..2463)
                     /locus_tag="VXD01_002081"
     CDS             complement(2107..2463)
                     /locus_tag="VXD01_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0602409.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(2701..2937)
                     /locus_tag="VXD01_002082"
     CDS             complement(2701..2937)
                     /locus_tag="VXD01_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602410.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(3044..4066)
                     /gene="ilvC"
                     /locus_tag="VXD01_002083"
     CDS             complement(3044..4066)
                     /gene="ilvC"
                     /locus_tag="VXD01_002083"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV0602411.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(4132..4608)
                     /gene="ilvN"
                     /locus_tag="VXD01_002084"
     CDS             complement(4132..4608)
                     /gene="ilvN"
                     /locus_tag="VXD01_002084"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV0602412.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(4601..6301)
                     /locus_tag="VXD01_002085"
     CDS             complement(4601..6301)
                     /locus_tag="VXD01_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV0602413.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTVEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
BASE COUNT         1907 a         1439 c         1052 g         1979 t
ORIGIN      
        1 aaaaaaaaca tatattcaac gaaaataatt agttcagaat tttcttactt cctttttaaa
       61 tccgataata tataggtttt gctagcctct acaccataaa tatttgctaa taaaaatact
      121 gtattattac cctcttaagg tgcgaaatta ttcaagttct taaaaaatgc ttctctattt
      181 ccgtaagata gcttatttct tcgatttaag aactgaagat gatagttcta acctttagaa
      241 atccaagcct tcactagctc aaaaactcct atctttcttc ctcaataaat catctgagag
      301 ataggtattc cttatgtcct tcaaattcat cactcctttg gatattgagg tgctagccta
      361 gaagcagaca cccgattatc taaaccatcc ttaatagaga tgacaagaca gataagctca
      421 gttaattact tatatatctt tttaatatgg tatatttgtc aacaaaaaga aatcaaatca
      481 taccttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcaa gttgctcaaa
      541 acactgtttt gaggttgcag atagagctaa cgtggtttga agagattttc gaagagtatt
      601 aaagacagtg tgactatgct tgtcaataga taggaaatca aaatgaagga tggaaatctg
      661 agccaaacat cataagtgct ataatgaaca gaagtaagaa ttgcacgata agttttctaa
      721 aaccatagga atcgtcccct ttcttcatct tcattatagc atatatacat cagttgtaca
      781 aataatatga tattttttat tagtcctcag acaagcatat tataaagcgt ttcattacca
      841 tttaagttaa tataagctgg atcaaaacct tccattctac gaatcaaacc tgcataatca
      901 tgcttatctg ctaaagcgat cccaattaat actgggcctg ttcccttgct agctcgtttg
      961 atatactcaa aacgtgtgat atcatcattt ggccccagga tatcatttac aaactcacgc
     1021 aaagctcctg gacgttgtgg gaaattgacc acaaaataat gtttgatacc atcataaatc
     1081 aaggcacgct cttccatttc tggcatacgg ttgatatcat tatttcctcc agaaatgata
     1141 caacaaatgg ttttcccctt aatatattca gctaaaacct ctaaagaggc gatactagct
     1201 gctccagcag gttctgcgac tatcccttgc ttagagtaaa ggtcaatcaa ggtttcagaa
     1261 atcaatccct catcgacacc taccaaagtt tgaatatgtt gacgagttgc ttcataggtc
     1321 aactgaccta ccttttgcac agcaatccca tccgcaaatt tatcaatttc cttgagtttg
     1381 actggacctc cagcctcaaa ggcagctttc atggaacgcg ctccattcgc ctctactccg
     1441 ataacctcaa tctctggact tgtttccttg atataggtag aaaccccggc aatgagaccg
     1501 ccaccaccaa caggaaccaa gacagcatca aaatcaatcg attcttttcg agcttcttct
     1561 aaaatctcat aagcaactgt tccttgacct gcttgaacat gagcatcatc aaaaggatca
     1621 ataaaggtac gattttcaga gactgtaaat tcttgagctg ctttggctga ggcatcaaag
     1681 gtatctccaa ctagtttaat agttacaaaa tccccaccaa aaaagcgaac ctgaccaatc
     1741 ttttgttgtg gcgtagtaat gggcataaag atagtagcag gaattttcat ttcattacaa
     1801 gtataggcta ctccctgcgc atgatttccc gcagaagcgc agactacccc acgttcacgt
     1861 tcttccttgc tgagctggga aatggcataa taggcaccac gaattttaaa ggagcgaaca
     1921 cgctgggcat tttctttttt caaataaatc ttagcaccat acttctccga taaataatga
     1981 tcgtaatcca gtggagtatt cacaaccaca ccgttcaaga ccttgtgagc cttgattata
     2041 tcttttgaac ttaacatata aaacctcttt ttctataaaa aacagtcact aatgactgtt
     2101 ttttagttat tcatctccga aaacttcagt aacactttca tggtatttat gagccatacg
     2161 aatcgaaaac tctttaggaa gttcataacg atttgtggaa atccaatcat ataaccattc
     2221 taccaaactt tcttcactat cattacgatg gaagataaaa tagtttaaaa tttctttata
     2281 ttctacatca ttcaaatcca acgtgtctac aaattgacta cgaggaacaa aattagaatc
     2341 taattttctt agttgatctg tcaattctcc caattgtaaa tccaactgaa aaaatagttt
     2401 ttgcagttgc ctatcagttt catcacatcc tgtcttgata gaaaacaaat tggtaatatt
     2461 catatgattt caacccctaa ataagtacat ctaatatccc acgaatagct aaagctaaag
     2521 ttttcgcagt ccagtcattt aaacccgatt ctttcaatcc agatgcaata atttgctcta
     2581 tttgatataa accgctatct atcgtctcat ttattctgcg aagaggacct tcaatatagg
     2641 ataaagcttc tccgaatcta acagctgatt taggtcctaa tgatttacca actatatttg
     2701 ttaatgtttt ttatttctca aaatccattt cgctatataa cgagcagatt tagtcgcacc
     2761 agctctctca aacggagaat gaatttcaag accttcttct ctagctattt gtgccaattt
     2821 gaagaattgt tcaaaggtca tatgcaacct accatcttca aaattagcat catcataaat
     2881 gttaattaca gcattttcat catacgacca atctgcttta ttttggtctg ctagcactat
     2941 taccgacggt gtaattacat tatacaacta gaaccaataa taacgatgca atttttctca
     3001 taatcttttt cataaaatca tctccagcgc tatatatttc taattagtta tagattttga
     3061 atgcatcatc gtcgttttta ccaacgaatg gcattgcttt acgcaattct gcaccaactt
     3121 tttcaatttc aaggttagct gcttgttcac ggtaagcagt caattttgga cgtccagctt
     3181 tatagtcatt tacaaagtca tttgcaaatt taccattttg gatgtctgcc aagacagcct
     3241 tcatattttc tttaacttgt tcagtgatta cacgtggacc tgatacatag tcaccgtatt
     3301 cagcagtgtt tgaaatagat tgacgcattt tcttgaatcc accttcgtag atcaagtcaa
     3361 cgatcaattt catttcgtga agaacttcaa agtaagccaa ttctggagcg taacctgctt
     3421 ctgtcaagac ttcgaaacct gcttcgataa gggcagtcaa accaccacaa agtacagctt
     3481 gttcaccaaa caaatcttct tcagtttctt ctttgtaagt tgtttcaaga agacctacac
     3541 gagccgctcc aacaccttta caccagtcca tagcaatgtt tttagcattt cctgttgcat
     3601 cttggtatac tgcataaaga gctggaacac caaatccttc ttcgtaagta cgacgtacca
     3661 agtgtcctgg tcctttagga gcacacatga agacatctac atccgcagga actttgataa
     3721 attcaaagtg gatgttgaaa ccatgggcaa atccaactgc gtttccagct tccaagtttg
     3781 gagcgatttc tgcttcgtac aattcttgtt gaatttcgtc tggcgccaag atcatgataa
     3841 catcagccaa cttagtagct tctgctactg tgtaagtatc aaatccatct tcttttgctt
     3901 tatcaaaaga tttacctgga cgtacaccta taataacgtc acgacctgaa tcacgcaagt
     3961 tttgagcatg cgcatgccct tgtgaaccat aaccgataac ggcgattttt ttaccgtcaa
     4021 gtgctgctac tttaacatct ttttcatatt ccatttgaac tgtcatagct tttctctctt
     4081 ttctattatt tattgccttt taggctggtt taataaattt aagttggatt tttaatcgcg
     4141 ggtaaatcca gttgcacccg ttcgagcaat attgcgaata ccgtatgggc gaatgactct
     4201 caatagggct tcgctctttt ctgcatttcc cgtcatctga atggtaatcg agcttggcgc
     4261 tacgtctacc actgttgcac ggaaaggttg aataatcgct aaaatctcag ctctcttctc
     4321 agctggcgct gacatcttaa ccaaaatcac ctcgcgctcc aaatgaggct tgtctgtaat
     4381 atctcgaatg cgaatcacat caatctgacg attgagctgt ttgatgattt gctccacttc
     4441 atcatgagaa gcaacatcaa taataatagt gatacgcgat acattcggat cttctgttgc
     4501 tccaacagag atgctttcaa tattaacctg acgacgagat aggacacctg taaagcgatt
     4561 gaggactcct gaacgatttt gtagttttgc tgttaacatt ctacgcatgg aactgcaccc
     4621 ccaacatctc atgattactc ttaccagccg gtaccattgg taacacctgt tccttacgag
     4681 aaatatctac ctcaattagc ataggaacat cctcagtgat gacttcaagg tcttgagcca
     4741 aggtctcagg attgtcaaac ttatagtttt taataccata agcctgcgcc atcaattgga
     4801 aatcaggaag ggtatcaaag accgactctg atgttctgcc ttcatagaag gattcctgcc
     4861 actggcgaac cattccgagt gaatgattgt tcagcataac caccttgatt ggcaccttgt
     4921 aaatattcaa aatagccaac tcctggttgg tcatttggaa accaccatcc ccaacaaaca
     4981 agactacttc cttatctggg ttagcaattt tagcaccgat tgctgctgga attccaaagc
     5041 ccattgttcc caaaccacct gaagtcacta actgacgttc attttggtag ggataatact
     5101 gagctgtcca catttggtgt tgaccaacgt ctgttaccac aatggcatct ccattcgtca
     5161 attcaccaat tcgttcaata actgcttgcg gttgaaccac acgctctttc ttgtcataag
     5221 aacgaacacg attcttgtct ttagtgactt tctcaatcca cttttcagta ttgttgtgaa
     5281 ctgttggttc tgctagcaac atttgcaagg ccttcttagc atctccaact acaggaatgt
     5341 ctgcactgat aatcttgcca atctcagctg ggtcaatatc aatgtgggca accttagcat
     5401 tcttagcgaa agtcttagga ttccccgtca aacggtcatc gaaacgagaa ccaatactaa
     5461 tcataaagtc cgcttccgtc atggcaatat ttgctgcgaa tgacccgtgc atgcctccca
     5521 ttccaagaaa gagtgggtga ctcgttgcaa tcgttccttg tcccaaaaga ctggttacca
     5581 ctggaatttg atagcgttct gcaaattcat ttagttccgt agcagcctca gcataactaa
     5641 ttccaccacc agctaacaag actggctttt tagccttgga caattgcttc aagattttct
     5701 tgatttgcat atcattcggc tcaacagtcg gctgataact tggtaaattc acttctggtg
     5761 aataaatgaa gtctgtttct aaagcagata tgtcttttgg taggtcaatt acaactggcc
     5821 ctggacggcc tgtagttgcg atatggacag cttccgtaat gatacgcgga atatcagctg
     5881 tctcacgaac ttggtaattg tacttagtga ttggcatggt aattcctacg atgtctgcct
     5941 cctgaaaggc atccttccca atccctgctc gcgccacctg acctgtaaag accaaaaggg
     6001 gaacgctatc gctcatagca tccgcaatcc ctgtaatggc atttgttgct cctggtccac
     6061 tagtgacgac ggcaacaccc aactttccag ttgatttggc ataaccttca gcttcatgca
     6121 aacaaccttg ctcatggcgc cctagaatgt ggcgaatgcc tttaaaatta tatatcgcat
     6181 cataaaaagg caaaaccgca ccaccaggat aaccaaagat ggtatcaact cctaaatcac
     6241 gaagtgtttc caaaactagg tccgaccccg tcttaggaga ttctaaactg attttctcca
     6301 ttgttcccct ttctttcctc ttaaaaataa cttgttacta tcataccatt ttttcaaaat
     6361 ttttcaagat aaaagaa
//
LOCUS       DAVLDI010000082         6089 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLDI010000082 DAVLDI010000000
VERSION     DAVLDI010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6089
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.083"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            174..490
                     /locus_tag="VXD01_002086"
                     /pseudo
     CDS             174..490
                     /locus_tag="VXD01_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            670..1329
                     /locus_tag="VXD01_002087"
     CDS             670..1329
                     /locus_tag="VXD01_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV0602414.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            1354..2421
                     /locus_tag="VXD01_002088"
     CDS             1354..2421
                     /locus_tag="VXD01_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0602415.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGSLIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            2524..3534
                     /locus_tag="VXD01_002089"
     CDS             2524..3534
                     /locus_tag="VXD01_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602416.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            3546..5237
                     /locus_tag="VXD01_002090"
     CDS             3546..5237
                     /locus_tag="VXD01_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0602417.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            5240..5950
                     /locus_tag="VXD01_002091"
     CDS             5240..5950
                     /locus_tag="VXD01_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0602418.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2043 a          841 c         1160 g         2045 t
ORIGIN      
        1 tttcaacata ctatattatc gcttaccaat atttgctttt atatttgcta aactttcaga
       61 aaaaaagttg gagtatatga tgctaggtga ctgcgtcatg ttagtaaacg aaatggaaat
      121 aactgatcat agagtagata acttatttga aaaagggaaa aatgagataa aagatccatg
      181 tagtagattt agcaatagga catataaaag ctttagaaaa agtatctgaa aaaacagatg
      241 tttatatcta taacctatgc tcgggagaag gcactagtgt attacaactt gtaaatacat
      301 ttgaaagtgt taataagatc cctattcctt ataaaatagt tccaagacgt tcaggagacg
      361 ttgcaacttg ttatgcaaat gcagacaaag agcatataag gaattaaatt ggaggacaac
      421 aaaatcgatt gaagacatgt gtagagatac atggaattgg caatcaaaaa atcccaatgg
      481 ctataattga tgatactgtc tatatgagtg ctgtattttg gaaaaattac ttaacctttt
      541 aatgaaatgc atatttaatg aaagataaat taaaaaaaat gtttgacagc gcttgacaaa
      601 ggaaacggtt tcattgtata atgtaaacat agtgacaccg atgtcaaata taaaaaagaa
      661 ggtctttata tgaaaaactt aacaaaaatt aagttcaaag agaatgggga atttaatcat
      721 ttccctggga atacagttgt agcaaatctt tatactaaac aagatttgat ggaagttgtt
      781 gatattattc aatcacgtta tagagaatta ccatttatcg ataagtttac tttaactcca
      841 aggaattcta ttcacatgac tgtaattgaa ttgttgtgcc atgaaaatcg tgaaacggag
      901 ttttggagca gtaatcttcc tctagataca cctttacagg aaatacatga ttactttgct
      961 aaacaacttg aaatttttcc attgttggat gaagaaattc atatgcgtat aactgaaatg
     1021 ggaaaacaaa acatactagt tgaacctgca gatgaagctt ctgcaaagag attagaagaa
     1081 attcgtactt atgtctcaga aaaagcaggt gtttgtttcc ctaatcatga tagatatcaa
     1141 ttccatattt caattgggta tcttcggatt cctctaaccg aagaggagga agaagagttt
     1201 actaaagtca gagcagaatt aactgaaatt ttattagaga agattccaac tattactgta
     1261 aaccgtattg actatactgt atttgaagat atgagacaat ttgttccata tcacgaaaaa
     1321 tttaaataaa ataataaaaa aggagaactt atcatgaaaa aaatgaaagt ttggtctact
     1381 gtacttgcaa cgggagttgc tcttactaca cttgctgctt gctctggagg ttcaaattct
     1441 acgactgctt cttcatctga agaaaaagct gataaaagtc aagaattagt tatctattcg
     1501 aactcagtct caaatggtcg tggtgattgg ttaactgcta aagcaaaaga agctggtttt
     1561 aatataaaaa tggttgatat cgctggcgct caattagcag accgtgttat tgctgagaag
     1621 aataatgcag ttgcagatat ggtatttgga attggtgctg ttgactcaaa taaaattaga
     1681 gatcaaaaat tactagtaca gtacaagcct aaatggttag ataaaattga tcaatcttta
     1741 tcagataaag ataattatta taatcctgtg attgttcaac cattagtttt aattggggcg
     1801 cctgatgtaa aagaaatgcc taaagattgg actgaattag gtagtaagta taaaggtaaa
     1861 tattcaattt atggtcttca aggtggtaca ggacgggcaa ttctagcaag tatcttagtt
     1921 cgttaccttg atgaaaaagg agatttaggc gtatcagaaa aaggatggga agttgcaaaa
     1981 gaatactttg caaatgccta tactcttcaa aaaggtgaaa gctcagttgt taaagcgtta
     2041 gataaagaaa gcccaattca atacggtatg atctggggtt ctggatcgtt aattggacaa
     2101 aaagaacaaa atgttgaatt caaagttatg actcctgaga ttggtgtacc atttgtaact
     2161 gaacaaacta tggttttaag cactagtaaa aaacaagcgt tagctaaaga atttattgat
     2221 tggtttggtc aatcagaaat tcaagtagaa tatagtaaaa aatttggatc tattcctgca
     2281 aataaagatg ccctaaaaga gttacctgaa gatacgaaaa aatttgttga tcaagtgaaa
     2341 ccacaaaata ttgactggga agctgttgga aagcatttgg atgaatgggt agaaaaagct
     2401 gaattagaat acgtacaata agaaataaga gttatttttt atgtccaagt ctctctatta
     2461 tttctaaatt taaggaagaa ataaagagag gcttttggtt tagtaataga gggagttagt
     2521 gagatgatta aatttgataa tattcaaatt aaatatggtg attttgttgc aattgataat
     2581 ctgaatttag atatacatga aggggaattc tttacatttc ttgggccttc aggatgtggt
     2641 aaatcaacta ctttgagagc attggtaggt tttttagatc catcatcagg aagtattgaa
     2701 gttaatggaa cagatgtcac tcatttggaa cctgaaaagc gtggaattgg tattgtattt
     2761 caatcttatg cgctatttcc aactatgact gtttttgata atattgcatt tggtttaaaa
     2821 gttaagaagg tagctccaga tgttattaaa gctaaagtat cagcagtggc agcaaaaatt
     2881 aagatctctg atcaacagtt acagcgtaat gtatcagaat tatctggggg tcaacaacaa
     2941 agggtagcat tggctcgtgc tctggttctt gaacctaaaa ttctttgtct agatgaacca
     3001 ttgtcaaacc ttgacgcaaa attacgtgta gatttgagaa aagagttgaa aagacttcaa
     3061 aaagagttag gtattactac tttatatgtt actcatgatc aagaggaagc cttgacttta
     3121 tctgatagaa ttgcagtctt taacaatgga tacatcgaac aggtcggtac accagtagag
     3181 atttatcata attctcaaac tgaatttgta tgtgatttta ttggagatat taatgttttg
     3241 accgatgaaa cagtccacga agtattattg aaaaatacaa gcgttttctt agaggataaa
     3301 aaaggataca ttcgattaga gaaagttcga ttcaatcgtg aaactgaaca agattttatt
     3361 ctaaaaggga caattattga tgttgagttt tctggagtta caattcacta tacaataaaa
     3421 gtttctgaaa gtcagattct taatgtaaca agtattgata gtcaggctgc tattagatct
     3481 gtcggagaaa gtgtggaatt atttatcaca ccatcagacg ttctgcaatt ttaaggaggt
     3541 gcagtatgcg tcataaatta aatttaaaag attggcttat tcgtttagga ttaatctggt
     3601 tcttagtaac atttattatt tatccaaact ttgatctagt agtgaatgta tttgtaaaag
     3661 gaggagaatt ttcccttgat gctgtacatc gtgttctaaa atctcagagg gcacttcaga
     3721 gtattatgaa cagttttaag ttagcatttt cactcattat tacagttaat gtcgtaggta
     3781 ttctttgtgt tctatttaca gagtactttg atattaaagg tgctaaaatt ttaaaattag
     3841 gttatatgac ctctttaatt tatggaggag tggttttagc gactggatat aaatttgtct
     3901 atggtcctta tggattgatt acaaaatttt tacaaaatgt tatcccttct ttagactcta
     3961 actggtttat tgggtatggt gcagtcttat tcattatgac attttcagga actgctaatc
     4021 atacattgtt tttaacaaat acaattcgaa gcgttgacta tcacactatt gaggctgctc
     4081 gaaatatggg agcaaaacca tttactgttt tccgaaaagt agtgttacca accttaattc
     4141 caactctatt tgcacttact attatggttt ttcttagtgg tttatctgca gtagcagcac
     4201 ccatgattgt tggtggtaaa gaatttcaaa ctataaatcc aatgattatt acatttgcag
     4261 ggatggggaa ttctcgtgat ttagctgcct tacttgcaat tattttaggt attgcaacta
     4321 caattttgct tactatcatg aataagatag aaaaaggtgg aaattatatt tctatctcta
     4381 agactaaagc gcctcttaaa aaacaaaaaa ttgcgtctaa gccttggaat atcattgctc
     4441 acattgtagc atatggattg ttcacagttt tcatgcttcc actaattttt atagtattat
     4501 actcatttac agatccagtt gcaattcaaa caggtaactt aacattatca aactttactt
     4561 tagaaaatta tcgcttattc tttagtaata gtgcggcatt ctctccattc ttggtcagct
     4621 ttatttattc tattattgct gcgacaacag caacaattct cgcagttgta tttgctcgtg
     4681 ttgtcagaaa acataaatct cgttttgatt tcttatttga atatggtgct ctacttcctt
     4741 ggttactacc aagtacactt ttagcagtaa gtttattatt tacttttaat cagccacaat
     4801 ttcttgtctt gaatcagatt ttggtaggta gtttggtaat tctacttatt gcatatatag
     4861 ttgtaaaaat cccattttct tatagaatgg tacgtgctat tttatttagt gttgatgatg
     4921 agatggaaga tgcagcaaga agtatgggtg cttcaccttt ttatactatg atgaaggtta
     4981 tcattccatt tattttaccg gttgttctct ctgttattgc tttaaacttt aactctttat
     5041 taactgactt cgacttatct gtattccttt accatcccct agctcaacca ttaggtatta
     5101 cgattcgatc tgcaggtgat gaaacagcaa catctaatgc acaagctctg gtatttgttt
     5161 atacaattgt tctgatgatt atttctggaa cggtattata cttcacacaa agaccggggc
     5221 gtaaagtaag gaaataatca tgacagccac tagtcttggg ttatcaaata ttgaaatagt
     5281 tgtcaggatt gttttatcag tagtcattgg tagtataatt ggtttagaga gagggagcaa
     5341 atcccagcct gcaggcatcc gaacttatag tattgtttgt ctagctgcat gtttgattat
     5401 gatgacgaat gaatacgtat cttataaatt tgggacagga gatcctacac gattaggagc
     5461 tcaagttata tcaggtgtgg gttttctagg cgctggaacg attcttatta cagataaaaa
     5521 gaaaattaca ggtctgacaa ctgcagcagg catttgggct tcggcaggaa ttggattagc
     5581 tattggagta ggtttttatg agggagctct tttagtagcc atttctgttt ggggtgtgat
     5641 atccatgttc caaccactaa aaaaatatct gcaaaatcgt tctaaaatga ttgaattgta
     5701 tatagtagtt aaatctacag aagcctataa tcgtgtattg gtttattgtg cagaaaatgg
     5761 tatcagaatg accgattcaa gaacagcgtt tggagatgtt aattctgaca gaattgaata
     5821 ctttgatgtt ccggacaaaa aaatagcgtc atttattact ctggaattat caggtagatt
     5881 tgaacatctt cgactgatgg aagaaattgc taatattgta ggtgttattt atgtcgaaga
     5941 aattagctga aatttagtaa acaaagggac agatgttttt gtccttttgt tttttagatg
     6001 ttttaatcat ctaatttttg agtagatttt tgctcagagg tttttatgaa agattataaa
     6061 atcaattttg atttaggtaa aatagaata
//
LOCUS       DAVLDI010000083         5842 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLDI010000083 DAVLDI010000000
VERSION     DAVLDI010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5842
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.084"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            105..584
                     /locus_tag="VXD01_002092"
     CDS             105..584
                     /locus_tag="VXD01_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV0602419.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            678..749
                     /locus_tag="VXD01_002093"
     tRNA            678..749
                     /locus_tag="VXD01_002093"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:711..713,aa:Glu,seq:ttc)
     gene            1001..2546
                     /locus_tag="VXD01_002094"
     rRNA            1001..2546
                     /locus_tag="VXD01_002094"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2598..2670
                     /locus_tag="VXD01_002095"
     tRNA            2598..2670
                     /locus_tag="VXD01_002095"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2631..2633,aa:Ala,seq:tgc)
     gene            2795..5696
                     /locus_tag="VXD01_002096"
     rRNA            2795..5696
                     /locus_tag="VXD01_002096"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5773..>5842
                     /gene="rrf"
                     /locus_tag="VXD01_002097"
     rRNA            5773..>5842
                     /gene="rrf"
                     /locus_tag="VXD01_002097"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1719 a         1135 c         1664 g         1324 t
ORIGIN      
        1 ccctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtttataagt gtagaaatga atattacctt catttatggg
      181 aattgtcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagatc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgcgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ctagtaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa agactgtata atagtaagag
      661 ttgaaaataa caactcaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg
      721 taacacgggt tcgaatcccg tacggactat ggtatgttgc ggttggaaca cttgatgaaa
      781 aaaagtttaa aaaagcttaa aaatcttcaa aaaagtgttg acaagtgaaa gtggctgtga
      841 tatactaata tagttgtcgc ttgagagaag caagtgacaa agacctttga aaactgaaca
      901 agacgaacca atgtgcaggg cgctacaaca taagttgtag tactgaacaa tgaaaaaaca
      961 ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga gtttgatcct
     1021 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gaaggaggag
     1081 cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct gcctggtagc
     1141 gggggataac tattggaaac gatagctaat accgcataag agtggatgtt gcatgacatt
     1201 tgcttaaaag gtgcacttgc atcactacca gatggacctg cgttgtatta gctagttggt
     1261 ggggtaacgg ctcaccaagg cgacgataca tagccgacct gagagggtga tcggccacac
     1321 tgggactgag acacggccca gactcctacg ggaggcagca gtagggaatc ttcggcaatg
     1381 gacggaagtc tgaccgagca acgccgcgtg agtgaagaag gttttcggat cgtaaagctc
     1441 tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac actgtgacgg tatcttacca
     1501 gaaagggacg gctaactacg tgccagcagc cgcggtaata cgtaggtccc gagcgttgtc
     1561 cggatttatt gggcgtaaag cgagcgcagg cggttagata agtctgaagt taaaggctgt
     1621 ggcttaacca tagtaggctt tggaaactgt ttaacttgag tgcaagaggg gagagtggaa
     1681 ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccggtggc gaaagcggct
     1741 ctctggcttg taactgacgc tgaggctcga aagcgtgggg agcaaacagg attagatacc
     1801 ctggtagtcc acgctgtaaa cgatgagtgc taggtgttag accctttccg gggtttagtg
     1861 ccgtagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt gaaactcaaa
     1921 ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa
     1981 gaaccttacc aggtcttgac atccctctga ccgctctaga gatagagctt tccttcggga
     2041 cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt
     2101 cccgcaacga gcgcaacccc tattgttagt tgccatcatt tagttgggca ctctagcgag
     2161 actgccggta ataaaccgga ggaaggtggg gatgacgtca aatcatcatg ccccttatga
     2221 cctgggctac acacgtgcta caatggctgg tacaacgagt cgcaagccgg tgacggcaag
     2281 ctaatctctt aaagccagtc tcagttcgga ttgtaggctg caactcgcct acatgaagtc
     2341 ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat acgttcccgg gccttgtaca
     2401 caccgcccgt cacaccacga gagtttgtaa cacccgaagt cggtgaggta accgtaagga
     2461 gccagccgcc taaggtggga tagatgattg gggtgaagtc gtaacaaggt agccgtatcg
     2521 gaaggtgcgg ctggatcacc tcctttctaa ggataaggaa ctgcgcattg gtcttgttta
     2581 gtcttgagag gtcttgtggg gccttagctc agctgggaga gcgcctgctt tgcacgcagg
     2641 aggtcagcgg ttcgatcccg ctaggctcca ttggtgagag atcaccaagt aatgcacatt
     2701 gaaaattgaa tatctatatc aaatagtaac aagaaaataa accgaaaacg ctgtagtatt
     2761 aataagagtt tatgactgaa aggtcagaaa ataaggttaa gttaataagg gcgcacggtg
     2821 gatgccttgg cactaggagc cgacgaagga cgtgacaaac gacgatatgc cttgggtagc
     2881 tgtaagtaag cgatgatcca gggatttccg aatgggggaa cccaacaggt aatacctgtt
     2941 acccacatct gttaaggatg tgaggaggaa gacgcagtga actgaaacat ctaagtagct
     3001 gcaggaagag aaagcaaaag cgattgcctt agtagcggcg agcgaaacgg cagaagggca
     3061 aaccgaagag tttactcttc ggggttgtag gactgcaatg tggactcaaa gattatagaa
     3121 gaatgatttg ggaagatcag ccaaagagag taatagcctc gtatttaaaa tagtctttgt
     3181 acctagcagt atcctgagta cggcgggaca cgtgaaatcc cgtcggaatc tgggaggacc
     3241 atctcccaac cctaaatact ccctagtgac cgatagtgaa ccagtaccgt gagggaaagg
     3301 tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct acaacaagtt
     3361 cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag ttacgttatg
     3421 atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtctgaat agggcgcctt
     3481 agtatcatga cgtagacccg aaaccatgtg acctacccat gagcaggttg aaggtgcggt
     3541 aagacgcact ggaggaccga accagggcac gttgaaaagt gcttggatga cttgtgggta
     3601 gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag ctttagggct
     3661 agcgtcgaca ttagagattc ttggaggtag agcactgttt gggtgagggg tccatcccgg
     3721 attaccaatc tcagataaac tccgaatgcc aatgaattat ggtcggcagt cagactgcga
     3781 gtgctaagat ccgtagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
     3841 attgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttag cttagaagca
     3901 gctattcatt caaagagtgc gtaatagctc actagtcgag tgaccctgcg ccgaaaatgt
     3961 accggggcta aaacaattta ccgaagctgt ggataccttt ataggtatgg taggagagcg
     4021 ttctatgtgt gatgaaggta taccgtgagg agtgctggaa cgcatagaag tgagaatgcc
     4081 ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg taagactaag gtttccaggg
     4141 gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgaaagg tgtatccgat
     4201 ggacaacagg ttgatattcc tgtactagag tatgtagtga tggagggacg cagtaggcta
     4261 actaaagcag acgattggaa gagtctgtct aagcagtgag gtgtgatatg agtcaaatgc
     4321 ttatatctgt aacattgagc tgtgatgggg agcgaagttt agtagcgaag ttagtgacgt
     4381 cacactgcca agaaaagctt ctagcgttta aacatactct acccgtaccg caaaccgaca
     4441 caggtagtcg aggcgagtag cctcaggtga gcgagagaac tctcgttaag gaactcggca
     4501 aaatgacccc gtaacttcgg gagaaggggt gctgacttta agtcagccgc agtgaatagg
     4561 cccaagcaac tgtttatcaa aaacacagct ctctgctaaa tcgtaagatg atgtataggg
     4621 ggtgacgcct gcccggtgct ggaaggttaa gaggagtgct tagcgtaagc gaaggtatga
     4681 attgaagccc cagtaaacgg cggccgtaac tataacggtc ctaaggtagc gaaattcctt
     4741 gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt gggcactgtc tcaacgagag
     4801 actcggtgaa attttagtac ctgtgaagat gcaggttacc cgcgacagga cggaaagacc
     4861 ccatggagct ttactgcagt ttgatattga gtgtctgtac cacatgtaca ggataggtag
     4921 gagtctaaga gatcgggacg ccagtttcga aggagacgct gttgggatac tacccttgtg
     4981 ttatggccac tctaacccag ataggtgatc cctatcggag acagtgtctg acgggcagtt
     5041 tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc ctcagaatgg
     5101 ttggaaatca ttcgcagagt gtaaaggtat aagggagctt gactgcgaga gctacaactc
     5161 gagcagggac gaaagtcggg cttagtgatc cggtggttcc gtatggaagg gccatcgctc
     5221 aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtt cacatcgacg
     5281 gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc ggtcccaagg
     5341 gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc gtgagacagt
     5401 tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga tctgctccta gtacgagagg
     5461 accagagtgg acttaccgct ggtgtaccag ttgtcttgcc aaaggcatcg ctgggtagct
     5521 atgtagggaa gggataaacg ctgaaagcat ctaagtgtga aacccacctc aagatgagat
     5581 ttcccatgat tatatatcag taagagccct gagagatgat caggtagata ggttagaagt
     5641 ggaagtgtgg cgacacatgt agcggactaa tactaatagc tcgaggactt atccaaagta
     5701 actgagaata tgaaagcgaa cggttttctt aagttgaata gatattcaat tttgagtagg
     5761 tattactcag agttaagtga cgatagccta ggagatacac ctgtacccat gccgaacaca
     5821 gaagttaagc cctagaacgc cg
//
LOCUS       DAVLDI010000084         5755 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLDI010000084 DAVLDI010000000
VERSION     DAVLDI010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5755
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.085"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..2316
                     /gene="phtD"
                     /locus_tag="VXD01_002098"
     CDS             <1..2316
                     /gene="phtD"
                     /locus_tag="VXD01_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV0602420.1"
                     /translation="YVTSHGDHYHYYNGKVPYDAIISEELLMKDPNYQLKDSDIVNEI
                     KGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQEHSHNHGGGSNDQAVVAARAQG
                     RYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDLSASELAAAQAYWNGKQGSR
                     PSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSLLRELYAKPLSERHVESDGL
                     IFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIARIIPLRYRSNHWVPDSRPE
                     QPSPQSTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAK
                     DLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDLLARIHQDLLDNKG
                     RQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERLGKPNSQITYTDDEIQV
                     AKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKE
                     KGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPH
                     YDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQR
                     NKNGQADTNQTEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLYKPSTD
                     TEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAMETLTGLKSS
                     LLLGTKDNNTISAEVDSLLALLKESQPAPIQ"
     gene            2527..5673
                     /gene="phtE"
                     /locus_tag="VXD01_002099"
     CDS             2527..5673
                     /gene="phtE"
                     /locus_tag="VXD01_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV0602421.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKKLSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEEPKTSEKVEKEK
                     LPETGNSTSDSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVI
                     KKNMADFTGEAPQGNGENKPSETGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENS
                     TDNGMLNPEGNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIE
                     LRLPSGEVIKKNLSDLIA"
BASE COUNT         2053 a         1039 c         1157 g         1506 t
ORIGIN      
        1 tatgtgacct ctcatggaga ccattatcat tactataatg gcaaggttcc ttatgatgcc
       61 atcatcagtg aagagctcct catgaaagat ccgaattatc agttgaagga ttcagacatt
      121 gtcaatgaaa tcaagggtgg ttatgtcatt aaggtaaacg gtaaatacta tgtttacctt
      181 aaggatgcag ctcatgcgga taatattcgg acaaaagaag agattaaacg tcagaagcag
      241 gaacacagtc ataatcacgg gggtggttct aacgatcaag cagtagttgc agccagagcc
      301 caaggacgct atacaacgga tgatggttat atcttcaatg catctgatat catcgaagat
      361 acgggcgatg cctatatcgt tcctcatggc aatcacttcc actatattcc taagagtgat
      421 ttatctgcca gtgaattagc tgctgcccaa gcctattgga atgggaagca gggatctcgt
      481 ccttcttcaa gttctagtca taatgcaaat ccagctcaac caagattgtc agagaaccac
      541 aatctgactg tcactccaac ttatcatcaa aatcaagggg aaaacatttc aagcctttta
      601 cgtgaattgt atgctaaacc cttatcagaa cgccatgtag aatctgatgg ccttattttc
      661 gacccagcgc aaatcacaag tcgaaccgcc agaggtgtag ctgtccctca tggtaaccat
      721 taccacttta tcccctatga acaaatgtct gaattggaaa aacgaattgc tcgtattatt
      781 ccccttcgtt atcgttcaaa ccattgggta ccagattcaa gaccagaaca accaagtcca
      841 caatcgactc cggaacctag tccaagtccg caacctgcac caaatcctca accagctcca
      901 agcaatccaa ttgatgagaa attggtcaaa gaagctgttc gaaaagtagg cgatggttat
      961 gtctttgagg agaatggagt ttctcgttat atcccagcca aggatctttc agcagaaaca
     1021 gcagcaggca ttgatagcaa actggccaag caggaaagtt tatctcataa gctaggagct
     1081 aagaaaactg acctcccatc tagtgatcga gaattttaca ataaggctta tgacttacta
     1141 gcaagaattc accaagattt acttgataat aaaggtcgac aagttgattt tgaggctttg
     1201 gataacctgt tggaacgact caaggatgtc tcaagtgata aagtcaagtt agtggatgat
     1261 attcttgcct tcttagctcc gattcgtcat ccagaacgtt taggaaaacc aaattcgcaa
     1321 attacctaca ctgatgatga gattcaagta gccaagttgg caggcaagta cacaacagaa
     1381 gacggttata tctttgatcc tcgtgatata accagtgatg agggggatgc ctatgtaact
     1441 ccacatatga cccatagcca ctggattaaa aaagatagtt tgtctgaagc tgagagagcg
     1501 gcagcccagg cttatgctaa agagaaaggt ttgacccctc cttcgacaga ccatcaggat
     1561 tcaggaaata ctgaggcaaa aggagcagaa gctatctaca accgcgtgaa agcagctaag
     1621 aaggtgccac ttgatcgtat gccttacaat cttcaatata ctgtagaagt caaaaacggt
     1681 agtttaatca tacctcatta tgaccattac cataacatca aatttgagtg gtttgacgaa
     1741 ggcctttatg aggcacctaa ggggtatact cttgaggatc ttttggcgac tgtcaagtac
     1801 tatgtcgaac atccaaacga acgtccgcat tcagataatg gttttggtaa cgctagcgac
     1861 catgttcaaa gaaacaaaaa tggtcaagct gataccaatc aaacggagaa acctcagaca
     1921 gaaaaacctg aggaagataa ggaacatgat gaagtaagtg agccaactca ccctgaatct
     1981 gatgaaaaag agaatcacgc tggtttaaat ccttcagcag ataatcttta taaaccaagc
     2041 actgatacgg aagagacaga ggaagaagct gaagatacta cagatgaggc tgaaattcct
     2101 caagtagagc attctgttat taacgctaag atagcagagg cggaggcctt gctagaaaaa
     2161 gtaacagatt ctagtattag acaaaatgct atggagacat tgactggtct aaaaagtagt
     2221 cttcttctcg gaacgaaaga taataatact atttcagcag aagtagatag tctcttggct
     2281 ttgttaaaag aaagtcaacc ggctcctata cagtagtaaa atgaatggag catattttat
     2341 ggagaagtaa cctttcgtgt tacttctctt ttttagaaaa acgtaacaga aacttgacaa
     2401 aagtaatttt aaatagtaga ctatttactg gttaattaaa tggttaaata atcggtttag
     2461 aaaactattt aataaagtaa aagaagttga gaaaaaaact tcatcattta ttgaaatgag
     2521 ggatttatga aatttagtaa aaaatatata gcagctggat cagctgttat cgtatccttg
     2581 agtctatgtg cctatgcact aaaccagcat cgttcgcagg aaaataagga caataatcgt
     2641 gtctcttatg tggatggcag ccagtcaagt cagaaaagtg aaaacttgac accagaccag
     2701 gttagccaga aagaaggaat tcaggctgag caaattgtaa tcaaaattac agatcagggc
     2761 tatgtaacgt cacacggtga ccactatcat tactataatg ggaaagttcc ttatgatgcc
     2821 ctctttagtg aagaactctt gatgaaggat ccaaactatc aacttaaaga cgctgatatt
     2881 gtcaatgaag tcaagggtgg ttatatcatc aaggtcgatg gaaaatatta tgtctacctg
     2941 aaagatgcag ctcatgctga taatgttcga actaaagatg aaatcaatcg tcaaaaacaa
     3001 gaacatgtca aagataatga gaaggttaac tctaatgttg ctgtagcaag gtctcaggga
     3061 cgatatacga caaatgatgg ttatgtcttt aatccagctg atattatcga agatacgggt
     3121 aatgcttata tcgttcctca tggaggtcac tatcactaca ttcccaaaag cgatttatct
     3181 gctagtgaat tagcagcagc taaagcacat ctggctggaa aaaatatgca accgagtcag
     3241 ttaagctatt cttcaacagc tagtgacaat aacacgcaat ctgtagcaaa aggatcaact
     3301 agcaagccag caaataaatc tgaaaatctc cagagtcttt tgaaggaact ctatgattca
     3361 cctagcgccc aacgttacag tgaatcagat ggcctggtct ttgaccctgc taagattatc
     3421 agtcgtacac caaatggagt tgcgattccg catggcgacc attaccactt tattccttac
     3481 agcaagcttt ctgccttaga agaaaagatt gccagaatgg tgcctatcag tggaactggt
     3541 tctacagttt ctacaaatgc aaaacctaat gaagtagtgt ctagtctagg cagtctttca
     3601 agcaatcctt cttctttaac gacaagtaag aaactctctt cagcatctga tggttatatt
     3661 tttaatccaa aagatatcgt tgaagaaacg gctacagctt atattgtaag acatggtgat
     3721 catttccatt acattccaaa atcaaatcaa attgggcaac cgactcttcc aaacaatagt
     3781 ctagcaacac cttctccatc tcttccaatc aatccaggaa cttcacatga gaaacatgaa
     3841 gaagatggat acggatttga tgctaatcgt attatcgctg aagatgaatc aggttttgtc
     3901 atgagtcacg gagaccacaa tcattatttc ttcaagaagg acttgacaga agagcaaatt
     3961 aaggctgcgc aaaaacattt agaggaagtt aaaactagtc ataatggatt agattctttg
     4021 tcatctcatg aacaggatta tccaggtaat gccaaagaaa tgaaagattt agataaaaaa
     4081 atcgaagaaa aaattgctgg cattatgaaa caatatggtg tcaaacgtga aagtattgtc
     4141 gtgaataaag aaaaaaatgc gattatttat ccgcatggag atcaccatca tgcagatccg
     4201 attgatgaac ataaaccggt tggaattggt cattctcaca gtaactatga actgtttaaa
     4261 cccgaagaag gagttgctaa aaaagaaggg aataaagttt atactggaga agaattaacg
     4321 aatgttgtta atttgttaaa aaatagtacg tttaataatc aaaactttac tctagccaat
     4381 ggtcaaaaac gcgtttcttt tagttttccg cctgaattgg aaaaaaaatt aggtatcaat
     4441 atgctagtaa aattaataac accagatgga aaagtattgg agaaagtatc tggtaaagta
     4501 tttggagaag gagtagggaa tattgcaaac tttgaattag atcaacctta tttaccagga
     4561 caaacattta agtatactat cgcttcaaaa gattatccag aagtaagtta tgatggtaca
     4621 tttacagttc caacctcttt agcttacaaa atggccagtc aaacgatttt ctatcctttc
     4681 catgcagggg atacttattt aagagtgaac cctcaatttg cagtgcctaa aggaactgat
     4741 gctttagtca gagtgtttga tgaatttcat ggaaatgctt atttagaaaa taactataaa
     4801 gttggtgaaa ttaaattacc gattccgaaa ttaaaccaag gaacaaccag aacggccgga
     4861 aataaaattc ctgtaacctt catggcaaat gcttatttgg acaatcaatc gacttatatt
     4921 gtggaagtac ctatcttgga aaaagaaaat caaactgata aaccaagtat tctaccacaa
     4981 tttaaaagga ataaagcaca agaaaactca aaacttgatg aaaaggtaga agaaccaaag
     5041 actagtgaga aggtagaaga accaaagact agtgagaagg tagaaaaaga aaagcttcct
     5101 gaaactggga acagtactag tgattcaacg ttagaagaag ttcctacagt ggatcctgta
     5161 caagaaaaag tagcaaaatt tgctgaaagt tatgggatga agctagaaaa tgtcttgttt
     5221 aatatggacg gaacaattga attatattta ccatcgggag aagtcattaa aaagaatatg
     5281 gcagatttta caggagaagc acctcaagga aatggtgaaa ataaaccatc tgaaactgga
     5341 aaagtatcta ctggaacagt tgagaaccaa ccaacagaaa ataaaccagc agattcttta
     5401 ccagaggcac caaacgaaaa acctgtaaaa ccagaaaact caacggataa tggaatgttg
     5461 aatccagaag ggaatgtggg gagtgaccct atgttagatc cagcattaga ggaagctcca
     5521 gcagtagatc ctgtacaaga aaaattagaa aaatttacag ctagttacgg attaggctta
     5581 gatagtgtta tattcaatat ggatggaacg attgaattaa gattgccaag tggagaagtg
     5641 ataaaaaaga atttatctga tctcatagcg taaggaatag cagtagaaaa agtctgaatc
     5701 aaaaatgaag ttctctcaaa agttagaaat aaaactctga ctttgggaga atttc
//
LOCUS       DAVLDI010000085         5454 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLDI010000085 DAVLDI010000000
VERSION     DAVLDI010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5454
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.086"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(130..201)
                     /locus_tag="VXD01_002100"
     tRNA            complement(130..201)
                     /locus_tag="VXD01_002100"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(166..168),aa:Arg,seq:cct)
     gene            complement(243..590)
                     /gene="rplS"
                     /locus_tag="VXD01_002101"
     CDS             complement(243..590)
                     /gene="rplS"
                     /locus_tag="VXD01_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV0602422.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(709..1038)
                     /gene="crcB"
                     /locus_tag="VXD01_002102"
     CDS             complement(709..1038)
                     /gene="crcB"
                     /locus_tag="VXD01_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0602423.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1032..1406)
                     /gene="crcB"
                     /locus_tag="VXD01_002103"
     CDS             complement(1032..1406)
                     /gene="crcB"
                     /locus_tag="VXD01_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV0602424.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(1403..1669)
                     /locus_tag="VXD01_002104"
     CDS             complement(1403..1669)
                     /locus_tag="VXD01_002104"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV0602425.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(1785..2228)
                     /locus_tag="VXD01_002105"
     CDS             complement(1785..2228)
                     /locus_tag="VXD01_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV0602426.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            2332..3267
                     /locus_tag="VXD01_002106"
     CDS             2332..3267
                     /locus_tag="VXD01_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV0602427.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3321..3605
                     /locus_tag="VXD01_002107"
     CDS             3321..3605
                     /locus_tag="VXD01_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV0602428.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(3662..4150)
                     /locus_tag="VXD01_002108"
     CDS             complement(3662..4150)
                     /locus_tag="VXD01_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEV0602429.1"
                     /translation="MSSYFVKITDASKAVKNGDQAEVQKLVTKMASDFERVENKDSEV
                     GKIVKEKLALSGDITEAKLTEISSALLAFEKEQNPVDLDAEKEKLVNRLSPRFETLEQ
                     AIASKDLEKVREAFKKMNSTWTINESVVRDNSTAHYGRVETAISFLPSSMETEPTDES
                     GT"
     gene            complement(4264..4935)
                     /locus_tag="VXD01_002109"
                     /pseudo
     CDS             complement(4264..4935)
                     /locus_tag="VXD01_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            complement(4938..5397)
                     /locus_tag="VXD01_002110"
                     /pseudo
     CDS             complement(4938..5397)
                     /locus_tag="VXD01_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT         1696 a         1190 c          981 g         1587 t
ORIGIN      
        1 caattttatc tgatgattgc ccaaattttt caataataaa acgcataata ttatggagac
       61 aatcccctat attatgcgtt cttttaatat caaagacttt ttgacaaact tctttgatat
      121 ctaattacat gccccctgca ggaatcgaac ctgcaactac tccttaggag ggagttgtta
      181 tatccattga actaagggag ctagataaaa actctgctga aaagcagagt tttttagtcg
      241 aattaacgac ggatttcttt gatacgagct gccttacctt gaagagcacg caagtagtac
      301 aatttcgcac gacgtacttt accgtaacgt acaacttcga ttttttcaac acgtggagtg
      361 tggattggga agatacgctc aacacctaca ccgttagaga ttttacgaac tgtgtagttt
      421 tcagagatgc cagcaccttt acgtgcaata acaacacctt caaaaatctg gatacgttca
      481 cggttacctt cgacaacttt cgcatgtaca cgaacagtgt caccaggacg gaatgatggg
      541 atatctgtac gaagttgacc ttcagtcaag ctttggatta atggattcat tttattctcc
      601 tatctttgtc aatcttgagg aatcttcctc agcggataaa ctgtattttt gtgcgtccat
      661 tacacacaag atatagttta ccaaatttct aaaaaaaagt aaagaaattt atagcaaaat
      721 tcctaaaaaa atcgcaacca aaccacctat gtaagtcaaa gtcaggtaag aataaaagac
      781 cttcttatca cttagcagtc tttgaagttc gtcattcaag gtcgaaaaag ttgttaaacc
      841 gccacaaaat cctgttgcta gaatagcata tacttcctta gactctacat gattgtagaa
      901 tactccaatt aaaaaacaac ctaaaagatt agctatgagc gttccgagtg gcaatttaga
      961 agcttgatta tagcgagaaa agaaataccg tacgagtgct cccaagccac aggcgattgc
     1021 aagatagacg attaccattt cttcctcccc aaatagtaag ctaaaagcag gcctccaccg
     1081 atactcaaaa gcaaatacag tatcaaacta agataacgcc ctgtatcaag cagcttcaca
     1141 gtatcaagca ttaggctgga aaaagttgtt aaacctccgc aaaaacccgt ccccagtgct
     1201 aaaatcaagc ccttactagt ccccttatag accagatagc ccttgacaag ataaatcaag
     1261 cagaaaattc ccagatagtt gacaaagaga gtgccccaag ggaaatctgg actggctggt
     1321 aaccaagtgg aaactaggta gcggacaagt ccgcccaaca tagcagctag aaaaatccct
     1381 agcggataaa attgttcttt tttcatttga tattttgatc ctgataatca cgcgaacgtt
     1441 tgagtatgtc cgaaaaagtc gcgacaatag tctcctgata gcgcttgtcc tctacacgac
     1501 ttctaacctt ttcaaaaata actgcttctc tcttagtatc taaaatcggt ttccctgaag
     1561 ccttcttata agcgacaact ccttcaacta agtgcattcg ttcttctaac agtttgacaa
     1621 tttggtcgtc gatttgatcg atttcttgac gaataatatc taaatccata cagtctcctc
     1681 ctttatttga attattgtat caaaaagcca tcaattaggc tagtaaaatc ccaactctcg
     1741 ataagaaaaa tgcactgatt gattacatca gcgcactttt atgcttatcc tactttagca
     1801 accaattctt ctgcgaattg ttccaagcgt tcaatatctt cttcctcggc agaaagatca
     1861 actttaacac actctgaacc tttttctgct cctgttgaca caaagacacg gtcaaagtca
     1921 tcaacagcct tacagaattc atcgtagaag gtatctcctg agccgaccac tccgtagatt
     1981 ttgccattca agttgagatc tgctaggtct tcgtagaagt ccatcatctc atctggcaat
     2041 tcaccatcac cataagtata ggtcgcaacg atagcgatgt ctgcttccaa gaagtctgaa
     2101 gcgtcaacag ttgtacattc atcaacatca acatccaagc ccaagtcacg taatttgtct
     2161 gctacaatat ctgcaatttc ttcggtatta ccggtcatac tggcaaatac aatttttgct
     2221 aatgccatat cgtcctcctc aatttatctt tctccattat atcacatctt tttcatttta
     2281 aaaataaaaa ttcttgtgct acaatgaaat gagaaagaat tgaggttatt tatggagatt
     2341 tgccaacaaa ttttagaaaa aattaaagaa tacgacacca ttatcattca tcgtcatatg
     2401 aaaccagacc ctgatgcctt gggaagtcag gtgggattaa aagccttgct ggaacatcat
     2461 ttcccagaaa aaaccatcaa agccgtcggt tttgatgaac caactcttac ttggatggct
     2521 gagatggatc ttgttgaaga tagagcctac caaggcgcac ttgtcatcgt ctgtgataca
     2581 gctaatactg ctcgtatcga tgataagcgc tatagtcaag gtgattttct cattaagatt
     2641 gaccaccatc caaatgatga tgtatacggt gacctgtctt gggtcgatac tagttcaagt
     2701 agcgctagcg agatgattac cctatttgcc caaacaaccc aactagcctt ggcagatcgc
     2761 gatgctgagt tgctctttgc aggaattgtc ggtgatacag gtcgcttcct ctacccttct
     2821 accactgcac ggactcttcg tctggctgct tatttgagag aacataactt tgactttgcg
     2881 gctctcactc gcaaaatgga cactatgagc tacaaaattg ctaaactgca aggctacatc
     2941 tacgaccatc tggaagtgga tgaaaatggt gctgctcgcg ttatcctgag tcaagaagtc
     3001 ttgaaacaat acaatgtaac cgatgctgaa actgcagcca ttgtcggtgc acctggacgc
     3061 attgacagag tgagtctctg gggaattttt gtcgaacagg ctgatggcca ctaccgagtt
     3121 cgcttacgca gtaaagtcca tcctatcaat gaaattgcca aggagcatga tggtggaggc
     3181 caccctctag caagtggtgc taattcctat agcctagaag aaaacgaaat catctaccaa
     3241 aagttaaaaa acttgcttaa aaactgataa aatacttgcc aaacttttca gaatctgata
     3301 gactagtatg gtaacaatct atggctcgca aagagaccat ggcagaaagg aaatattgca
     3361 aaatgaaaaa agatatccat ccagaatatc gcccagttgt cttcatggac acaactactg
     3421 gttaccaatt ccttagcggt tcaacaaaac gctctaacga aacagttgag ttcgaaggcg
     3481 aaacttaccc attgatccgt gtggaaattt catcagactc acacccattc tacactggac
     3541 gtcaaaagtt cactcaagca gatggacgcg tggatcgttt caacaaaaaa tacggtctca
     3601 aataatgata agagaacagt ttcggctgtt cttttttgtt tcttgaaatc aactgctgtt
     3661 ttcatgttcc agactcatct gtaggttcgg tttccatgct actaggcagg aaggaaatag
     3721 ctgtttcaac acgtccataa tgagctgtac tattgtcacg aaccacactt tcattgatgg
     3781 tccaagtgga attcattttc ttaaaagctt ctcggacttt ttccaaatct ttggaggcaa
     3841 tggcctgctc taaggtttca aaacgaggac ttagacggtt taccaatttt tccttttccg
     3901 catctaggtc aacaggattt tgttcttttt caaaagctaa tagagctgag gaaatttcgg
     3961 tgagtttggc ttcagtaata tctccagata gagctaactt ttccttaaca atcttaccaa
     4021 cctcagaatc cttattttct actctttcga agtctgatgc catcttcgta acgagtttct
     4081 ggacctcagc ctgatcacca tttttaaccg ctttggatgc atctgtgatt tttacgaaat
     4141 aagaactcaa gctttcttgg gcacctgctg gggaaagaat taagaattaa gaattaagaa
     4201 ttaagaatta agaattaaga attaagaatt aaaaatgaca aagctaaaac aagcaaccag
     4261 cttttagcct tccaataatt tctgaccaat gtagcctcct ttctccacac caccaaagca
     4321 agtaaaaagt ccactaccta tgtgagtgat gtattcattc atcttatcag tagcacctag
     4381 gttagtttga accttaacaa agttatcagg atccttctgg aaagaaatga agagcaaacc
     4441 cgtatcaaac tgaccagtct tttcatcaat gccatctgag taagaataag aacgacgtaa
     4501 aagtggctta tccacttctt tggccaaaca aacatgcgaa tcatcaggta agagactcaa
     4561 atccacttca tcaaactcat ttttcttacc aaagggggca ccgcatttct ccccttacgg
     4621 atgagattgc gaatagcgtg aaaggcaatt tgctcatcat ctgcacaagc atgaatcaca
     4681 atatctccac cagtatattt ttcacgtaat tgctccttag gaaatagagg taaatccctg
     4741 aacagtcgag ggcgcttgtt ttccaagttc atccttttca agaaacttgc agatacacca
     4801 aaagtcagcg tcaaacgatg aggattgagc ccaactgtca tccgtccaat ccttgaatag
     4861 ctggataatt ttatctctat ccgtcgtatg caggtccaag acaacaaaat agatattctt
     4921 ttgcatgggc gtactatttg gtacatcaag cgaaccttat gaaaaggtct actgatttta
     4981 aagcgctttc ttgtcttctt gaattgagat tttattttta gacgcgacaa tggtttgagc
     5041 gtctgctttc ttaggatgtt ctggacgtgg cataatattt cgccaaccat ggcgcttcaa
     5101 cagttgatag aaggcgtcac gtgtgtagga acgacctaac tcctttttat aagcctgaaa
     5161 taaggcatca attgtaacaa attctcctga ctctgcagcc ttcaaatgac gggcaagaaa
     5221 ggctttctct tcctcaactg tcatatatgc atggttacga ccactacgtg tttcttgaag
     5281 gagagagtcg agttcgaact cctcatattt ttttacattt cgctaaatcg ttgtttgatt
     5341 acagtctaaa agttctataa tctctttata agatttgccc atcagacgaa atataataaa
     5401 ttgaaactag aatagtacac ctctacttct aaaatattat tagaaatcga tttg
//
LOCUS       DAVLDI010000086         5370 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLDI010000086 DAVLDI010000000
VERSION     DAVLDI010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5370
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.087"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            41..874
                     /locus_tag="VXD01_002111"
     CDS             41..874
                     /locus_tag="VXD01_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HEV0602430.1"
                     /translation="MNPLKECYEKNGILIAAHRGTNGGNILQNTSKAYLNSIRHNADM
                     FEVDVIRSKDGEFFAFHDGQEPLVFGEKIDIRTLSSEEIQRKECFNSLNEPILQKIEK
                     ISDVLKNFEGQSLINIDRSWFYWDTFLDKLKTYPSLNQVLLKSPVKKELLEMLRDSGL
                     NIMYMPIIKTIEELDFVLSFEGINIVAVELVFQDLENPIISKKVIDDLHEKGLLIWVN
                     ALTLSDSIILSAKIDDDTAIAHDGESWGKLVSIGFDIIQTDWPLLLYQYLVEKNKKIK
                     K"
     gene            901..1962
                     /locus_tag="VXD01_002112"
     CDS             901..1962
                     /locus_tag="VXD01_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0602431.1"
                     /translation="MFKNFKKIAFTSSLILLAACSNNASNTNQSTDEGSVDKSQEIVI
                     YTNSASNGRADWLQTKASEQGYNLRLVDISGGELADRLIAEKNNAVADMVIGLNKLEF
                     NRIKAEKLLVKYSPKWADEVDSSLGDSEGYYSPIVNQPLVLIGNKDAKMPSDWTDFTD
                     SSYKGKYGISKLSTGTSKNIFASIVSRYKDEKGELGISDEGWKVAKAYLKNAHVYAEG
                     EDYISSIMDNNNELKYSMMWGSGVLQNQKEREYKFQVMSPKVGVPYVTEQVGILNTSK
                     KQALLKEFVDWFGSSELQKEWSDKFGSIPANKKALEQAKDELKQFANSVKPQELDWEF
                     IGKNIDSWIEKAQLEFVEQ"
     gene            1979..2983
                     /locus_tag="VXD01_002113"
     CDS             1979..2983
                     /locus_tag="VXD01_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602432.1"
                     /translation="MITFKDIQIKYNDFIAIDNLNLTINEGEFFTFLGPSGCGKSTTL
                     RALVGFLEPSQGQILVDNQDITNLDPEKREIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VSPEIIKAKVHEIAKKINISDEQLNRNISELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVSLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGFIEQVGTPY
                     DIYNQSETQFVCDFIGSINKISQEVLKKLQGENKYFKETEGYIRLERVKLEKTSPQDL
                     SITGVISDIEFNGVLIKYKVDLSNSESIHIIEKNDGLSRHIIEEKVTMYINPRDIMQF
                     "
     gene            2995..4689
                     /locus_tag="VXD01_002114"
     CDS             2995..4689
                     /locus_tag="VXD01_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0602433.1"
                     /translation="MRKSLNWKDWLIRLGVLWLIFALIIYPNIELLSGVFYKNGSFTL
                     EAFNKIIHSQRAMSSIFNSFILAISMVFTVNIVGTLIVLLTEYWDIRGSKILKLGYMS
                     SLVYGGIVLATGYKFVYGANGLVTKTLSSIIPGLAPNWFQGFGAVLFIMTFACTSNHI
                     MFLTNAVRSVDYHTIEAAKNMGASPLKVFFSVVFPTFKPTLFALTILTFLTGLSAVSA
                     PLIVGGKDFQTINPLIISFAKTTSSRDLAALLAIMLGLATILLLTLLNHVEKGGNYVS
                     VSKTKASIKKQIISSPLWNTLAHIVAYVLFAIYMLPIVLIILYSFTDSLTIKTGTLDL
                     SKFTLANYANLFTDAQSFRPYLVSVVYAILAAVIATIIAIVISRIVHKNKSKFDKFFE
                     YGALIPWILPGTLIALGLMFTYNIPHLILFNLVLVGTVIILLIAYTIQKLPFSYRMIR
                     AVFFSIDNDMEEAARSMGASSFYTMVRVIIPYILPVVLSVVVLNFNSLLSDYDLSVFL
                     YHPLFQPLGIVIKQSTDETATLNAQAMMFVYSVILMIMSSAALYLSSLFQGKRGKR"
     gene            4691..>5370
                     /locus_tag="VXD01_002115"
     CDS             4691..>5370
                     /locus_tag="VXD01_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV0602434.1"
                     /translation="MNLSYELSIWEILLRCFLAILFGGIVGYERGVKNQAAGIRTYLL
                     VCLGTCVVMMTNQFITSRYGSGDPSRMGAQVISGLGFLGAGTIMVTNQKVKGLTTAAG
                     LWSSATIGLAIGIGFYEGAILAGVVLIAVLTLFTPLKDYLNSKTKIADYYLVFSSLEG
                     YNRLLIYLNTSGIKILEIQNGIGNLDEERQLNKIKSTKVSCYLSLKLNENFEHLKLME
                     EMHNIAGV"
BASE COUNT         1855 a          741 c          980 g         1794 t
ORIGIN      
        1 ggatacaatg taattaacaa taaagatagg agaaaataat ttgaatccat taaaagaatg
       61 ctatgaaaaa aacggtatac taattgcagc acaccgtggt acaaacggag gaaatatatt
      121 acaaaacaca tcaaaagcct atttgaattc catacgccat aacgcagata tgtttgaggt
      181 tgatgtaatt cgttcaaaag atggagaatt ttttgcattt cacgatgggc aagaaccttt
      241 agtatttggt gaaaaaattg atattagaac tttgagttct gaagagatcc aaagaaagga
      301 atgttttaat tcactgaatg aacccatatt acaaaagatt gaaaaaattt ctgatgtatt
      361 aaaaaatttt gagggacagt ctttaataaa tatagataga agttggtttt actgggatac
      421 cttcctagat aagttaaaaa catatccatc tttgaatcaa gttcttttaa aatcacctgt
      481 aaaaaaagaa ttattggaaa tgcttagaga ctctggtttg aatattatgt atatgccaat
      541 tatcaaaaca attgaagagt tagattttgt tctctcattt gaaggaataa atatagtagc
      601 tgtcgaactt gtattccaag atttagaaaa tccaatcata agtaagaaag taattgatga
      661 tttacatgaa aaaggattac ttatttgggt taatgcttta accttaagtg attcaattat
      721 tctttcggct aagattgatg atgatacagc tattgctcat gatggcgaat cttgggggaa
      781 attggtttca ataggatttg atattattca aacagattgg ccattattac tttatcaata
      841 tctagttgaa aaaaataaaa aaataaaaaa ataaaaaaat aaaaataaag gagaactatc
      901 atgttcaaaa actttaaaaa gattgcattc acttcttcac taattttact tgctgcttgc
      961 tcaaacaatg cttcaaatac aaatcagtct actgatgaag gaagtgttga taaatctcaa
     1021 gaaattgtaa tctatacaaa ttcggcttct aatggacgtg cagattggtt acaaaccaaa
     1081 gcatcagagc aaggatacaa tcttcgtttg gtagatattt caggtggaga actagctgac
     1141 cgtttgattg cagaaaagaa taatgctgtg gctgatatgg taattggatt aaataaatta
     1201 gaatttaacc gtattaaagc tgaaaaactt cttgtaaaat actcaccaaa atgggctgat
     1261 gaagtagata gctctttggg agattctgaa gggtattatt caccaattgt aaatcaacca
     1321 ttagttttga ttggtaataa agatgctaaa atgccatccg actggacaga ttttactgat
     1381 tcatcttata aaggtaaata tggtatttca aaattaagta caggtacatc taagaacatc
     1441 tttgcaagta ttgtttcgag atataaagat gaaaaaggtg agttaggaat atctgatgaa
     1501 ggttggaaag ttgcaaaagc ttaccttaaa aatgcacacg tttatgcaga aggtgaagac
     1561 tatatctctt caattatgga taataataat gagctaaaat atagtatgat gtggggatct
     1621 ggtgttctac aaaatcaaaa agaacgtgaa tataaattcc aagtaatgtc accaaaagtt
     1681 ggtgttcctt atgtaactga acaagttggg attttaaata caagtaagaa gcaagcatta
     1741 ttaaaagaat ttgtagattg gtttggctct tcagaacttc aaaaagaatg gtctgataaa
     1801 tttggttcaa ttccagctaa taaaaaagct ctagagcaag caaaagatga actcaaacag
     1861 tttgctaata gtgttaaacc acaagaactt gactgggagt ttatcggaaa aaacatcgat
     1921 tcttggattg aaaaagcaca gcttgaattt gttgaacagt aatagttagg attaagtgat
     1981 gattacattt aaggatattc aaattaagta taatgatttt attgccatcg ataatctcaa
     2041 tttaacaatc aatgaaggag agtttttcac atttttagga ccaagtggtt gtgggaaatc
     2101 aacaactctt cgtgcactag ttggattttt ggagccttca caggggcaaa tactagttga
     2161 taatcaagat attacgaatt tagatccgga aaaacgcgaa attggtattg tgtttcaaag
     2221 ttatgcatta ttcccaacaa tgactgtttt tgataatatt gcttttggtc taaaagttaa
     2281 aaaagtttct cctgaaatta ttaaagctaa agttcatgaa attgcgaaaa aaattaatat
     2341 ctcagacgag caactaaacc gaaatatttc tgaattatca gggggacaac aacagcgtgt
     2401 agctttagca cgtgcattag tattagaacc aaaaattctt tgtttggatg aaccgttatc
     2461 aaacctagat gccaaactac gagtttcgtt gagaaaagaa ttgaaacgat tgcaaaaaga
     2521 actaggaatc actactcttt atgtcacaca tgatcaagaa gaagcattaa cattatcaga
     2581 taggattgct gtgtttaata atggatttat tgagcaagtt ggcacgccgt atgatattta
     2641 taatcaatcc gaaactcaat ttgtctgtga ttttattggc tcaatcaata aaattagcca
     2701 agaagttctt aaaaaattac aaggcgagaa taaatacttt aaagaaactg aaggatacat
     2761 acgcttagag cgtgttaagt tagagaaaac ttcacctcaa gatttatcta taacaggagt
     2821 aattagtgat attgagttta atggtgtact tattaagtat aaagtagact tgtcgaatag
     2881 tgaaagtatt catattatcg aaaagaatga tggactatca cgtcatataa tcgaagaaaa
     2941 agtcactatg tacattaatc cgcgtgatat aatgcaattt taaggagatt gtgcatgaga
     3001 aagagtctaa actggaaaga ttggctcata agattaggag ttttatggct aatctttgcc
     3061 ctgattattt atccaaatat tgaacttttg tctggagtgt tttataaaaa tggttcattt
     3121 actctagagg cattcaataa gattatacac tctcagagag cgatgagtag tatatttaat
     3181 agctttattt tggcgatttc aatggtcttt actgtaaata ttgttgggac attgattgtt
     3241 ctactcacag agtactggga tattaggggt tcaaaaatac ttaaattagg ttatatgagc
     3301 tctctagtat atggaggaat tgtattagcg acaggatata aatttgttta tggcgctaat
     3361 ggtcttgtaa ctaaaacgct ctcaagtata attccaggtc ttgcccctaa ctggtttcaa
     3421 ggatttggtg cagtattgtt tattatgaca tttgcttgta cctcaaatca cataatgttt
     3481 ttaacaaatg cagttcgtag tgttgattat catacaattg aagcagctaa aaatatgggt
     3541 gcaagtcctt taaaagtttt ctttagtgtg gtttttccaa cttttaaacc tacgttattt
     3601 gccttaacca tcttaacttt tttgacaggt ctttcagcag tttctgctcc tttgatagta
     3661 ggggggaaag attttcaaac tattaaccca ttgattatca gtttcgctaa aactacaagt
     3721 tcgagagatt tagcagcttt actagctatc atgttaggtt tagcaactat tctattattg
     3781 acacttttga atcatgtcga aaaaggaggt aattatgtat ctgtttcgaa aaccaaggct
     3841 agtattaaga agcagataat ttcttctcca ttatggaata ctcttgctca cattgttgcg
     3901 tatgtattgt ttgcaatcta tatgttacca atagttttga taattctata ctcgtttaca
     3961 gactcgttga cgatcaagac gggaacttta gatctatcta aatttacgtt agcgaactat
     4021 gctaatttat ttacagatgc tcaatcattt cgtccttacc tagtcagcgt tgtttatgca
     4081 attttagctg cggtaattgc tacaattata gcaatagtaa tttcacgtat tgtacataaa
     4141 aacaagagta agttcgataa attctttgag tatggtgcac taataccatg gatattgcca
     4201 ggtacattga ttgcactagg attaatgttc acttataata tacctcattt aatactattt
     4261 aatttagttt tagtaggaac agtaattatt ttacttattg catatactat tcaaaaatta
     4321 ccattttctt atagaatgat tcgggctgta tttttcagta tagataatga tatggaagaa
     4381 gcagcacgta gtatgggtgc atctagtttc tacactatgg tgcgagttat tataccgtat
     4441 attttaccag tcgtattatc agtagttgtg ttaaacttta attctttatt atctgactat
     4501 gacttatctg tattcttgta ccatccactt ttccaaccat tgggaatcgt tattaaacag
     4561 tctactgatg aaacagcaac tttaaatgca caggcaatga tgtttgttta ttctgtaatt
     4621 ttaatgatta tgtctagtgc agctctttat ttatcaagcc tattccaagg taaacgaggt
     4681 aagagataat atgaatcttt catacgaact gagtatttgg gaaatacttc ttaggtgctt
     4741 tttagcgatt cttttcggtg gcattgttgg ctatgagcga ggagtcaaaa accaagcagc
     4801 agggattaga acctacttac tagtttgttt gggaacttgt gttgtaatga tgacaaatca
     4861 gttcatcact agtcgttatg gtagcggtga tcctagtcga atgggagccc aagtaattag
     4921 tggcttgggt ttcctagggg caggaacaat catggtaact aatcaaaaag ttaaaggttt
     4981 aacaacagca gctggattat ggtcttcagc aactattggt ttagctatag gcattggttt
     5041 ttatgaaggt gctattttag ccggagttgt actcatagca gttttaactc tatttactcc
     5101 tcttaaagat tatttaaact cgaaaactaa aattgctgat tactacttgg tttttagttc
     5161 tttagaaggt tataatcgtt tacttatata tttaaataca tcgggtatta agattttaga
     5221 aattcaaaat ggtataggaa atcttgatga agaacgtcaa ttaaataaaa ttaagtcaac
     5281 aaaagtgtcc tgctatttat cattaaaatt aaacgaaaac tttgaacatt taaaattaat
     5341 ggaagaaatg cataatattg ctggtgttat
//
LOCUS       DAVLDI010000087         5283 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLDI010000087 DAVLDI010000000
VERSION     DAVLDI010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5283
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.088"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..212)
                     /locus_tag="VXD01_002116"
     CDS             complement(<1..212)
                     /locus_tag="VXD01_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV0602435.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIV"
     gene            complement(370..2820)
                     /gene="phtA"
                     /locus_tag="VXD01_002117"
     CDS             complement(370..2820)
                     /gene="phtA"
                     /locus_tag="VXD01_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV0602436.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            complement(3074..4807)
                     /gene="ptsP"
                     /locus_tag="VXD01_002118"
     CDS             complement(3074..4807)
                     /gene="ptsP"
                     /locus_tag="VXD01_002118"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV0602437.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(4813..5076)
                     /locus_tag="VXD01_002119"
     CDS             complement(4813..5076)
                     /locus_tag="VXD01_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV0602438.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
BASE COUNT         1391 a         1115 c          982 g         1795 t
ORIGIN      
        1 acaatttgtt cggcgttgat cccctccctc ttactgactt catctggtgt caagttttct
       61 gccttttgac cagcctgatc accatctata taagcaactc gattagactc tttcttatcc
      121 tgaccagctt ggtaacgtcc aagctcatag gaacaaacac ttagggcaag gactgccact
      181 gaacctgcta gatatttttt attgattttc attctttcct cttttcttaa gtatatttga
      241 ttcactataa agtaataaac cggttaatta actagttaat agtttactct ttttaatatt
      301 gcttgtcaag aattttacat atatacataa taaaaatgaa agcctcttta tcgagacttt
      361 catttttcat tagtttattt tttccttact tacagatgaa ggattacttc cttttaacaa
      421 cgcaagtaat ttttctgctt ctgccatgat actattgtta tccataattt gaagagtcaa
      481 attatttcgt aaaccagcta gagtttctgt tgcattggct ttcagactag aatccgttac
      541 tttcgcaagc aaaacttctg cttctttgag ttgggcttct actttttcag tctctacttg
      601 agggacttct ggctcagcag gtgtttcctc tactggctct tcatccgctt tgaagttctt
      661 atttggatct tcactgtggt ctttcttgcc taacacatgc tcactggcat tgccccatcc
      721 atcattagaa tgtggacgtt cgtcagggtg ttctacgtag tacttaatcg tcgcaaacaa
      781 atcttccaag gtatagccat ttggagcttt gtatgtgtga tcatcaaacc aagcaaattt
      841 aatattatgg taatgatcct tatgaggaat aatcaaatta ccgtttttaa cctcaactgt
      901 atgctcaacc atatatggaa gtcgaacgag tggaattcgt ttttcccctt tcacacgatt
      961 gtaaatagct gctgcactat ctccagttgg atttgcttta acatctgcgt ctggagatgg
     1021 aggtaggata cctttttctt tagtataggc ttgagctgca actttttcct tatcagaaag
     1081 gctatctttt ccaatccagt gactatggcc catatgaggc gttacatatg catctccttc
     1141 atcactgatt atatcatgtt catcaaaaat gtaaccatct gacgttgtat acttatcagc
     1201 taattgagca atacgaactt cgtcttcagt atactcaatt tgagaatttg gcttgccaag
     1261 tcgctctgga tgggtaattg gtgctaggaa tgccaataaa tcatctacca atttttcttt
     1321 attagtcgat tcatcattca agcgttctaa taatttgtct aaggcttgga aatcagaatt
     1381 acgaccctta ttttcaaaca aggctttatg agcctcagtt aacagattat atgctttatc
     1441 ataaaattct tggtcacgag gagcaacatt ttctttttta gcagttaaag tgtgtgaaac
     1501 actctcttgt tttgataact tactttcaag atttttaaca gtttcagatg gtaaatcttt
     1561 cgcaaagaca taacgagaga tgcccttttc ttcgaataca tatccttccc caacttttcg
     1621 taccagctga ctaaccaaag aagaatttga gtctatttta agatttggtg caggttgcgg
     1681 gcctggacta ggttccggag tcggttgtgg acttggttgt tctggccttg aatctggtac
     1741 ccaatggttt gaacgataac gaaggggaat aatacgagcg attcgttctt ccaattcaga
     1801 catttgagag taagggatga agtggtaatg atctccgtgt ggcactgcaa cacctctagc
     1861 tgttcgactt gtgatttgcg ctgggtcgaa aacaaggcca tcagattcta catgtcgttg
     1921 actcaaaggc agtttgtaga gctgtttcaa gagactatca atgtcattac tttgacttgc
     1981 ttgactgtta gtgttgctgt tgttgcttgt gttagtattt gtagttcctg gattgcttac
     2041 agaaggtacc cagtttgttc ttgaagtgtt atcgctattt tgtcggcgat aggttcttga
     2101 atttgacaga tttccccgac cagataggaa ggcttctgca gcagccaact cgctagctga
     2161 taactcattc ttaggaatgt aatggtaatg atctccatga ggaacgatat aagcatcacc
     2221 agtatcctct atgatatcag aagcattaaa gatataacca tcatctgtag tatagcgtcc
     2281 ttgcgaacgt gccaaggcaa cagcaccatc gtttcttgga gtcccacctt cacgatgttg
     2341 actatgctct tgtttttgtc gattgatttc ctcttttgta cggacgttat ccgcgtgggc
     2401 agcatcctta aggtaaacat agtattttcc atctaccttg ataacatatc cacccttgac
     2461 ctcattaaca atatcctcat cttttagctt atagtttgga tctttcatga gtaattcttc
     2521 actgaaaatc gcatcataag gaaccttacc attgtaataa tgatagtggt cgccatgtga
     2581 agtgacatag ccttggtctg ttatcttgat gacgatttgt tcggcattga ttccttcacg
     2641 cttgctaacc tcatcaggag tcaaattctc cgttttttgc gtcgcttgtt ttccatctat
     2701 ataggaaaca cgattatttt ccttaaccgt tctagcttga tacagtccca actcgtaaga
     2761 acaaacactt aaaatcaaag ctgccgcaga accaacaagg tatttcttat taattttcat
     2821 cgaaactctc tttctatttg atatttctag ttgcaattca tttctaaatt gcagaaactc
     2881 ctctctatta cttaactggt taatagttta ctcctaaatc tccaacttgt caagaatttt
     2941 atgaaccatt taagtatttt ttgttctgac cactactttt tcaaggttgg actttctata
     3001 agaaagattt tcttgaaaat tctttttaaa atatcaaaaa aatccctgta actgagttgc
     3061 agggactttt cgattaatca aaattaacgt attctttttg aagttcaaga acttcttcca
     3121 ttgttgagca ttctgtaagg gcacggtttg cgtactcttc catcttagct gtgtcgagtt
     3181 tcttcatcaa gctgcgtgta cgaagtacag atgttgctga catagagaac tcatccaagc
     3241 ccattccgac aagaagtgga acagcttgtt ggtcaccagc catctcacca cacataccag
     3301 cccatttacc ttcagcgtga gctgctttga tcacattgtt aatcaagcgt aggattgatg
     3361 ggttgtatgg ttggtaaagg tatgaaactt gttcgttcat acggtctgct gccattgtat
     3421 attggatcaa gtcgtttgta ccaattgaga agaagtcaac ttctttagca aattggtctg
     3481 caagcatagc cgctgcagga atctcgatca tgataccaac ttggatgtta tccgcaactg
     3541 caacaccttc agcaagaagg tttgcttttt cttcatcaaa gactgctttc gctgcacgga
     3601 attctttcaa gagcgcaacc attgggaaca tgatacgcaa ttgaccgtga acagacgcac
     3661 gaagaagagc acggatttgt gtgcggaaca tagcatctcc agtctcagag atagagatac
     3721 gaagagcacg gaatccaagg aatgggttca tttcgtgagg catatcgaag taaggaagtt
     3781 ccttatctcc accgatatcc attgtacgaa cgacaacagg tttaccgttc attccttcaa
     3841 gaacagcctt gtatgcttca tactgctcat cttcagttgg gaagtcttga gaatccatgt
     3901 acaagaactc tgtacggtaa agtccaacag cttctgcacc gttgttgtta acaccttcaa
     3961 cgtcttttgg agtaccaata ttggcagcca actcgaagtg tttaccgtca gcagtcactg
     4021 tttgagcatc tttcaaaagt gcccattcag ctttttgttt cgcataggct tcaccagctg
     4081 ctttaaattc tgccgcttgt tcatctgttg ggttgataat cacttctcca gtgatcccgt
     4141 taacagcaag gatgtcaccg tctttaacga tttcagtgat gttgtttgta cctaatacag
     4201 cagcaatttc aagtgtacgt gccatgatag ctgagtggct tgtacgtcca ccaatgttgg
     4261 ttacaaaagc ttttacaaag tttttgtcca attgagctgt atctgaagga gtcaagtcat
     4321 gcgcaatcac aatcacttct tcattgatag aagctgggtt tggcaatttt ttaccaagaa
     4381 ggtttgccaa tacacgtttt gtcacgtcgc ggatatccgc tgcgcgttct tgcatgtatg
     4441 ggttgtcttc catgccttca aagatagtga taaacatatc tgtaacttct ttcagacctg
     4501 cttctgcatt cactttcttc gcacggatag tttccttgat ttggctgatc atttctgggt
     4561 cagcaagaac cattaagtga gcatcaaaaa cttgagctgc ttcttcaccg agcgtaccta
     4621 ctgctttctc gcgaataaca gaaagctcgt cttgtgatgc ctgtagagcg gcatcaaggc
     4681 gagcttcttc tgcgtttgta tcttcgactg taatagtctc aaatgacaaa tccggctgaa
     4741 cgagtagata tgcttttgca actgcaacac cgtcagatgc tgcgattcct ttaagcattt
     4801 ctgtcatttc ccttatgcca atccttcttt ttccattgtt tctgagattg cagcgatagc
     4861 gtcatctgca tctgcacctt cagctgagat agttacgtca gcaccttggc caacaccaag
     4921 actcataaca cccataattg atttaaggtt aactgattta cctttgtact caagagtgat
     4981 atctgaagca aatttgctag cagtttgtac caacaatgtt gctggacgtg cgtgaatacc
     5041 tgtttctgcc actacgtgga aatctttaga agccatagtt tgactctcct tttgttcttt
     5101 ctttttttga gttatatgtg ataaccctta caatttagta ttataccatc ttctaggatt
     5161 tttttcaagc attttctgga ttttccttca atttcctttc agataacttg ctgaaaatct
     5221 tctatcctag ataacaaaac acaggatata gtttctttaa aaacaattta taggataatc
     5281 att
//
LOCUS       DAVLDI010000088         5185 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLDI010000088 DAVLDI010000000
VERSION     DAVLDI010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5185
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.089"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(341..1069)
                     /locus_tag="VXD01_002120"
     CDS             complement(341..1069)
                     /locus_tag="VXD01_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV0602439.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1227..2636
                     /locus_tag="VXD01_002121"
     CDS             1227..2636
                     /locus_tag="VXD01_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0602440.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQIIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2654..3949
                     /locus_tag="VXD01_002122"
     CDS             2654..3949
                     /locus_tag="VXD01_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV0602441.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3954..4262
                     /locus_tag="VXD01_002123"
     CDS             3954..4262
                     /locus_tag="VXD01_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV0602442.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4259..4567
                     /locus_tag="VXD01_002124"
     CDS             4259..4567
                     /locus_tag="VXD01_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV0602443.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1742 a          873 c          949 g         1621 t
ORIGIN      
        1 tctagcaatt tgttagaagt cacagtctac tattctaacc tcagtatact atatgtgtta
       61 caagaaaaga ctcaaaaact tctcgtcagt gtaagaatgt ttgaaacact atttaaaact
      121 aaataactat aagaagtaga tcaggtgaac aatttcagta cctactctat aagctatacg
      181 aagatatttt tcaacatgat ggataaaacg atcactcttt taaagccatc ttatttagaa
      241 aagagaaacc atttaagcat agatgggacc ttcttgccct gttttaaatt tttcttaaac
      301 tagagtctgt aaaagattgg cttcattttc acattttctc ctaggaggaa tgtcgtaatg
      361 caaaagaatt aaattcaaat aaatcatagc gatgacgact aatcgagtac tcaaacggag
      421 ttccgttatc caaataagcc acttgttcta cttcaaatac cggttccgtt ggaaggagct
      481 gcaagtaatg ttgctcattt tctgaactag aagaagctcg caagattttt gtagcactgg
      541 caatatgcaa tcctaacttt ccttcaatgt aattgtaaat cgatttttgt aaaatatctt
      601 cagtaatacc tggaataaca tcggtactca tataagtttg ttccagaaca taaggtttac
      661 cgtcaataat acgcaggcgg taaatattat aaactggact ctgcaaagcg acctgtagtt
      721 tttctgctaa aaattcattt gcaaattcta atttgaagtg aataatcctc gagtcaattg
      781 tagaatgagc atcttcagat atttttgtca gtccccggat atctctttct ggaacgatta
      841 attttctttt tgagctgcca cgagagagaa caaaggttcc ctgcccacgt tttctaaaaa
      901 ttaagccctc agaaactaac aagtctaaag cttttttgat cgtcattcga ctacaggcaa
      961 actgtttagc taatgtcatt tcatcaggca attgttcgtt catggtatat ttattacaaa
     1021 gaatcttttc acgaatctca ttgtaaataa ataaatattt tgtactcatt taatctggtt
     1081 ctctctataa tattctaata gtagtataac aaagttcaag aaatgaggca aacacaagat
     1141 atgtataaac aatttttaaa aatgtctaga caaattttaa aattatgcta tactttatgt
     1201 atagaataat agaaaggagg ttgagcatga aaaaaaagtt agtatttcct aatctgtttt
     1261 ggtggggggc tgcttctagc ggacctcaga cagaaggtca atatggaaaa gtacatgaaa
     1321 atgtgatgga ctactggttc aaaacgcatc cagaagattt tttcgataat gtcggacctc
     1381 ttgtagccag taactttttt catacttaca ccgaagattt ccacttgatg aaggaaattg
     1441 gagttaattc tttccgcact tccatccaat ggagtcgact catcaagaat ttagagacag
     1501 gtgagcctga tccaaaaggt attgctttct acaatgccat cattgaagaa gctaaaaaga
     1561 accagatgga tcttgtgatg aatttacatc attttgattt accagtggaa cttcttcaaa
     1621 aatacggtgg ttgggaaagc aaacatgtag tggagttatt cgtgaagttt gccaagactg
     1681 ctttcacatg ctttggagat aaggttcatt actggacaac tttcaatgag ccaatggtca
     1741 ttccagaagc aggatactta tatgctttcc attatccaaa tctaaaagga aagggaaaag
     1801 aggccgtaca aatcatctat aatctaaacc ttgctagtgc aaaagtgatt caactatatc
     1861 gctcattagg acttgatgga aagattggga ttattttaaa cttgacacct gcttatccaa
     1921 gaagtaattc tccagaagac ttagaagcaa gtcgatttac agatgacttc tttaacaaag
     1981 tcttcttgaa tccagctgtt aaaggaactt tcccagaaag attggtaaaa cagctagaga
     2041 gagatggcgt gttatggagt cataccgaaa aagagcttca actgatgaaa tcaaatacgg
     2101 ttgattttct tggagtaaac tactaccatc caaaacgtgt tcaagcacaa gcaaatcctg
     2161 aggaatatca gacgccctgg atgccagacc aatacttcaa agagtatgaa tggccggagc
     2221 gtcgcatgaa tccatatcgt ggttgggaaa tttttccgaa agccatttat gatattgcta
     2281 tgattgtgaa ggaagaatat gataatattc catggtttat cagtgaaaac ggaatgggtg
     2341 ttgaaaacga agcacggttt atcggtgaaa atggagttat cgatgacgtg tatcgtattg
     2401 aattttatga agaacattta agatggctac ataaagccat tgaagaggga agtcactgtt
     2461 ttggatacca cgcttggacc gcatttgatt gctggtcttg gaataatgca tataagaatc
     2521 gttacggatt tatctccgtt gatttagaaa cgcaaaagag aaccatcaag agctcaggaa
     2581 gatggtatcg caaagtaagt gacaataacg gttttgaagt agaaattgag gagtaaagag
     2641 aggagatatt cagatgaaaa actcaaaatt tatagatcaa tttgccacct ttgctggtaa
     2701 actagggaac caaattcatt taaaaaccct aagagatgca ttcgtaacag taatgccatt
     2761 atatattttg gcaggtttaa tcgttctttt gaacaacacg gtatttaagt ggattttcca
     2821 aggggataca ttaacaagat tccaatattg gggaataaca attgcaaacg gtactttaag
     2881 tatttcaggt atgattattg ctgtaatggt tggttatttc ttagctaaaa acagagattt
     2941 cgaaaacccg ttagcagcat caatgctatc attagtttct ttaattgtga tgatgccaaa
     3001 tacagtttct gtagttcctg acggagcaaa agatgcggta aacatttcag gtgttctttc
     3061 attcaacaac acaggtacag gcgcaatgtt cgccggggtt atcgtagcga ttattgcaac
     3121 agaattattc attgaattat caaacgttaa agctttacaa atgaaccttg gtgaaaatat
     3181 tccaccagct gttagtagat catttagcgt attacttcca gtcatgaccg tcatctcctt
     3241 atttggggtt gtttcagcat tattattcaa tataactgga atgaacttaa tctcaatcat
     3301 tacaatcttt attcaagaac caattcgtca tattggtaca agcttaatcg gggtcattat
     3361 tatttactct ttaggaaata tgttatggct atttggtatt caccaagcag ttatttacag
     3421 tgccatccta gaaccattac tattaattaa cattactgaa aacatcactg cagcaaataa
     3481 tggacaagcc attccacaca tcatcaacct atcacaaata caaacattcg ctttaatggg
     3541 tggtagtgga tctacattat gtttattaat agcaacattc ttagtgagtc gcaatgctgt
     3601 ctctaaaaac gtggctaaat tatcttttgg acctggtatc ttcaatatca atgaaccagt
     3661 attattcggt tacccaatcg tttataacat ttcattagct attccattta tcacagttcc
     3721 agtccttggt attttaatca gctacttagc aacagttaca ggattcatga gtcctgcatt
     3781 tatacaagtt ccttggacta caccagtatt cttaaatgca tggttagcaa cagcagggga
     3841 cgtgagagca gttctagttc aattcatcat ctttgcactt ggagttcttc tatacattcc
     3901 atttatcaaa gttaatgaca aagttgttga gcaagaaatg gaaggttaag attatgaaac
     3961 aaattttatt agtatgtaat gcgggaatgt cgacaagtat gcttgttaaa aaaatgcaac
     4021 aaagtgcgac tgaacgtggg attgaaattt ctatccaagc aaaatcaatg acagaagcta
     4081 aaaagaatat ccatgaagca gatgtcattc taattgggcc acaaattcgt tatgagttac
     4141 ttgctgtgaa agaaattgca ggaaatatcc ctgtagatac cattgatatg cgggattacg
     4201 gaatgatgaa tggagcaaaa gttctggaac aagcacttgc atggatagga gaaataagat
     4261 gacagaagaa atggaatata tctgttttca gctcattgcc aatagtggag cagccaaatc
     4321 atcctttatt gaagccatcc aactagctaa ggcaggaaat ttaaaagaag cgaaaattaa
     4381 agttgaagaa gcggaagact ccttagtaga agcgcacaag attcactcta atctcataca
     4441 aaaagaagct actggagaaa aaataggatt ctccttgcta tttatgcatg cagaagacca
     4501 aatggcttca acagagatta ttcagttgct atctaaagaa ttcatcgatc tctatcaaaa
     4561 taaataggaa cactgtcgtt cccatctgtc tttattaatg acggctacat tgtaggaacc
     4621 tccaaaagtt ggacaaaatg attgaaagga ttggatcctg cattacacaa gatccaatcc
     4681 ttttctttta ctctagtttt tataatgtgt tgaatttaga atagtccact gcagtttcta
     4741 aaaaattgct ggaaatagat gttaagctcc aatttatttg tttatatctt atttcagttt
     4801 actatactag cttattattc tagtaaaaaa ttgaatgagc cactatttat ttaatatgta
     4861 tgatgaggga atgactcaaa aacttcttgt cgatataaga atatctgaga tagtatttta
     4921 aaacgaaagg actataaaag ctcatttcct tcgcacttat tttatagaga tctatcatta
     4981 tactctttag aaatcaaaaa gcaacacacc ttgtcatcgt tttatcgtaa atctgttaat
     5041 gagggggcta gtcttatctg caatctcaaa tcagtgtttt gagctgaatg gcactcgttt
     5101 tctagtttgc tctttgattt taattgggcc ttagtaaata ctactcttaa attaaactat
     5161 agtgaattga aataagatgt gaaca
//
LOCUS       DAVLDI010000089         5130 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLDI010000089 DAVLDI010000000
VERSION     DAVLDI010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5130
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.090"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            65..508
                     /locus_tag="VXD01_002125"
     CDS             65..508
                     /locus_tag="VXD01_002125"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV0602444.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            510..1025
                     /locus_tag="VXD01_002126"
     CDS             510..1025
                     /locus_tag="VXD01_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0602445.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATSLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            1039..2400
                     /gene="radA"
                     /locus_tag="VXD01_002127"
     CDS             1039..2400
                     /gene="radA"
                     /locus_tag="VXD01_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV0602446.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            2473..2970
                     /locus_tag="VXD01_002128"
     CDS             2473..2970
                     /locus_tag="VXD01_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV0602447.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            3186..3809
                     /locus_tag="VXD01_002129"
     CDS             3186..3809
                     /locus_tag="VXD01_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV0602448.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIKDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            3954..4922
                     /locus_tag="VXD01_002130"
     CDS             3954..4922
                     /locus_tag="VXD01_002130"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV0602449.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
BASE COUNT         1393 a          890 c         1261 g         1586 t
ORIGIN      
        1 gtgctttttc cgaataaata agatagaata atctagaata aatgataata gaaaagagaa
       61 aattatgaaa attcgtggtt ttgaattggt ttcgagtttt acagatgaaa atttattgcc
      121 caagcgtgag acagcgcatg cggctggtta cgacttaaag gttgctgtgc gtacagttgt
      181 tgcgccagga gagattgtct tggttccgac aggggttaag gcttatatgc agccgactga
      241 ggttctctac ctctatgatc gttcttcaaa tcctcgtaag aagggcttgg ttttaattaa
      301 ctcagttggg gtcattgatg gggattatta tggaaatcct ggaaatgaag ggcatatttt
      361 tgcgcagatg aagaatatca cagaccaaga ggttgttctt gaagttgggg aacgtattgt
      421 ccaggctgtt tttgctactt tcttaattgc agatggagat gcagctgatg gcgttcgaac
      481 tggtggattt ggatcgacag ggcactagaa tgaagattat ctttgtacgt catggggagc
      541 cagattaccg tgagttagag gagcgttctt atataggatt tgggatagat ttggcaccct
      601 tgtctgagat gggacggcag caagtccaga aattgagcaa aaatccttta ctctcgtcag
      661 ctgaaataat cgtatcttct gcagtcacaa gagctttaga aacggcttcg tatgtggtct
      721 gtgctacgag tcttccttta agagtagagc ctttattaca tgaatggcag gtctataaaa
      781 caggaataga aaactttgaa acagctagaa gactgttttt agaaaacaag ggggagttgc
      841 ttcctaatag tcctattcaa tatgagacag ctacggaaat gaagtctcgg tttctagaat
      901 gtatgtctaa gtatcgagaa catcagactg tggtagttgt tgctcatcga atgctcatgc
      961 gccagtttgt gccaaatgag aagattgatt tttgccaagt gattgagtgt gagttagaga
     1021 tatagaaaga ggtttgtcat cgcaaagaaa aaagcgacat ttgtatgtca aaattgtggg
     1081 tataattccc ctaaatatct gggacgttgc cccaactgtg ggtcttggtc ttcttttgtg
     1141 gaagaggttg aggttgccga ggtcaagaat gcgcgtgtgt ccttgacagg tgagaaaacc
     1201 aagcccatga aactagctga ggtgacttcc atcaatgtca atcgaaccaa gacggagatg
     1261 gaggaattca accgtgtgct tggaggcgga gtggtaccag gaagtctcgt cctcatcggt
     1321 ggggatcctg ggattgggaa atcaactctt ctcctacaag tctcaaccca gttgtcccaa
     1381 gtggggacag ttctctatgt cagtggggag gagtctgccc agcagattaa actacgtgca
     1441 gagcgcttag gtgatattga tagtgagttt tatctctatg cagagaccaa tatgcagagt
     1501 gttcgtgcag aagtggagcg tatccagcca gactttctca ttattgattc catccagacc
     1561 atcatgtctc ctgagatttc aggggtgcag gggtctgttt ctcaggtacg tgaagtgacc
     1621 gctgaactca tgcagttggc caagaccaat aacattgcca tctttatcgt aggtcatgtg
     1681 accaaagaag gaaccttggc tgggcctcgt atgttggagc atatggtgga tacggtgctt
     1741 tactttgaag gggagcgtca ccacaccttt cgtattttga gagcggtcaa aaatcgtttt
     1801 ggttccacta atgagattgg gatttttgag atgcagtcgg gcggcttggt tgaggtactc
     1861 aatccgagtc aagttttcct agaagagcgt ttggatgggg cgactggttc ctccatcgtt
     1921 gtaaccatgg aagggacgcg tccgattttg gcggaggttc aggctttggt aacaccgacc
     1981 atgtttggaa atgccaagcg tactacgaca ggacttgatt ttaaccgtgc tagcttgatt
     2041 atggctgttt tggaaaaacg ggcagggctt ctcttgcaaa atcaggatgc ctatctcaaa
     2101 tctgctggtg gtgttaaatt ggatgaacct gccattgact tggctgttgc agttgctatt
     2161 gcttcgagct acaaagacaa gccaactaat cctcaggaat gttttgtcgg agaactgggc
     2221 ttgacaggag agattcggcg cgtgaatcgt attgagcaac gcatcaacga agctgctaaa
     2281 ctgggcttta ctaagattta tgtacctaag aattccttga caggaatcac tctgcctaag
     2341 gaaattcagg tcattggcgt gacaacgatt caggaagtct tgaaaaaggt ctttgcataa
     2401 tccgtgacaa attctcttaa aaatgataag ataggagaaa tatttgacta tcaaattttc
     2461 aaggagggaa tcgtgtcgta ttttgaacag tttatgcaag ccaatcaggc ttatgttgcc
     2521 ctacatgggc agttaaattt gccacttaaa cctaaaacca gagtagccat tgtgacctgt
     2581 atggactcac gtttgcacgt tgcgcaagct ctaggtttgg cacttgggga tgctcatatc
     2641 ttgcggaatg caggtggtcg agtgactgaa gacatgattc gttcgctagt tatttcccag
     2701 caacaaatgg ggacaagaga gattgtggta ttgcaccata cagactgtgg tgctcagacc
     2761 tttgaaaatg aaccttttca ggagtattta aaagaggaat taggtgtaga tgtgtcagac
     2821 caggacttct tgcccttcca agatatagaa gagagtgtac gcgaggatat gcaactgctt
     2881 atcgagtctc ccctaatacc agacgatgtc attatctctg gtgccattta caatgttgat
     2941 acaggaagta tgacagtcgt agaattataa atacttcatt tagaaagaaa gtgtatgaag
     3001 aaaagcagta ttttatttat ttttatttta ttgctatgta ttggtttaca gtatgaaacc
     3061 atctactata cggacggttc gaggtcaggt gcggaatatg gactaatggg agtttctatc
     3121 tttctagctc tcttttacat gattccggct ctttattttc tcttccgtat tgggaaaaat
     3181 gggaattgcc aaagaaggtt ttgattctgt ctttattggg agggatgttc ctttcaggct
     3241 ggttgtctag ttttgctaat acttatatcc atgatttact gggggttctt ttcccagata
     3301 gtacattttt aaatgccttt gaaagtgcta ttgtggctcc tttggtagaa gaacccttga
     3361 aattattgcc acttgttttt gttttggctt tgattcctgt gcgaaaatta aaatctttgt
     3421 ttttacttgg aattgcttcc ggtttgggat tccaaatgat taaggatatt ggttatattc
     3481 gtacggattt gccagagggc tttgatttta ctatttcgcg aattttagag cgtatcatct
     3541 caggaattgc ctctcactgg actttttcag gtctagctgt agtaggtgtt tacttgcttt
     3601 acagagccta taaaggacag aaggttggca agaaacaggg ccttattttt ctaggtttag
     3661 ccttgggaac tcacttcttg tttaactctc cttttgtgga gttggaaaca gagttgcctt
     3721 tagcgattcc agtggttacg gctattgctc tctatggttt ttatcatgct tattgctttg
     3781 ttgagaaaca caatgagttg atgacctaga atatttttca aaagaatgat gcaagggtac
     3841 aaatatggtg cccttctttt atttttgatt gaaaaatagt gcaaaaagcg ctacaatggt
     3901 agatggaaaa tcttgtgaaa agcacaagtt atacatatat accggaggaa atcatgtctt
     3961 tttctgattt aaagctgttt gccctttctt ctaataaaga attggcagaa cgtgtggcgc
     4021 aggagattgg gatagagttg gggaaatcaa gtgttcgcca attttcagat ggagagattc
     4081 aggtcaacat tgaagaatca atccgtggga aacacgtctt tatcctacaa tcaactagtt
     4141 cgcctgtaaa tgacaatctg cttgaaattt tgattatggt agatgctttg aagcgtgcga
     4201 gtgcagaatc tgtcaatgtt gtcatgcctt actatgggta tgcacgtcag gatagaaagg
     4261 cgagagcgcg tgagccaatc acttcaaaac ttgtcgcaaa tatgcttgaa gtagctggag
     4321 tggatcgttt attgaccatc gacttgcatg ctgcgcaaat tcaaggattc tttgatattc
     4381 ctgtggatca tttgatgggt gctcctctga ttgcagatta ttttgagcgt cgtggtatgg
     4441 ttggttctga ctatgtggtt gtcagcccgg accatggagg ggtgactcgt gctcgtaagt
     4501 tggcagaatt tttgaaaaca tctatcgcta ttattgataa acgtcgtagc gttgataaga
     4561 tgaatactag tgaagttatg aacatcatcg gtaaggttga aggcaagact tgtatcttga
     4621 ttgatgatat gattgatacc gctggaacga tttgtcatgc ggcagatgct cttgcggaag
     4681 ctggtgctgt tgaagtctat gcaagctgta cgcacccagt tctttctggt cctgctacgg
     4741 acaatatcca aaaatcagct attaagaaat tggttgtttt ggataccatc tatcttccag
     4801 aagagcgttt gattgataag attgagcaga tttcaatcgc tcatctccta ggggatgcta
     4861 tcgtacgtat tcatgaaaaa cgaccacttt ctccactttt cgatattgag aaaaaaattt
     4921 aatgaccaag cctgagatga ttctcaggtt ttttcgtctt ttttccgaat aaatagatag
     4981 tagcggtgaa tctagtaaag ctagatttaa aactgtgata taataaaaag agaagaaata
     5041 tgactgtacg tcatcagaag tttcagcgac catcattttt gaacagtgat agcacttgaa
     5101 tcgacgcttt ctaaggagaa ttctagtagg
//
LOCUS       DAVLDI010000090         5068 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLDI010000090 DAVLDI010000000
VERSION     DAVLDI010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5068
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.091"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     regulatory      complement(84..172)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(381..1010)
                     /locus_tag="VXD01_002131"
     CDS             complement(381..1010)
                     /locus_tag="VXD01_002131"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV0602450.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(1012..1794)
                     /gene="thiM"
                     /locus_tag="VXD01_002132"
     CDS             complement(1012..1794)
                     /gene="thiM"
                     /locus_tag="VXD01_002132"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV0602451.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKHPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(2082..2750)
                     /locus_tag="VXD01_002133"
     CDS             complement(2082..2750)
                     /locus_tag="VXD01_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV0602452.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(2965..3053)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(3305..4441)
                     /gene="lctO"
                     /locus_tag="VXD01_002134"
     CDS             complement(3305..4441)
                     /gene="lctO"
                     /locus_tag="VXD01_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV0602453.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
BASE COUNT         1556 a         1092 c          792 g         1628 t
ORIGIN      
        1 agtttcgtaa aagaaaaaac tctaattaca gatacgaatt agagttcagc ttacaagatt
       61 agacagttct tttcgacata cgaaaaaaac atttcacatt tcccttcgcc agtcttaact
      121 gtatcaggtt caatgggtat catctcagcc taaagcaccc caaatgtctt tattatttaa
      181 ttatgtgatt attataacac acattttata ctagttcaag aaattgaact ggaaatacag
      241 ccttgcactc acaaagacag cagatttttc ttttgcaaaa aacaaatgac ctgtttgatg
      301 aattagccat tcaagctgaa tctggacata gctttttaaa aaaggaaaat cctacttact
      361 tagaatccaa ggatagatat ctattgttca ctcatttccc gaacagtttt ttctatattt
      421 tttgcatacg atattgccga aatgattgaa acgccatcca tattggtctt tataatgtct
      481 ttaatatgtt tcgtctgtat cccaccaatt gcaactaaag gcatttgtgg caatagtttt
      541 ctcatcaatt caagaccttc ataacctata gtaccaccag catcatcctt tgactgggta
      601 ccaaatacag gcccaacacc tacataatct acatattcaa cttttgattg ttgaaattct
      661 tcttcgtttc ttatagaaag accaattatt ttatctggca tcaattttct aatttcatca
      721 acaccaatat catcttgacc tacatgtacg ccatcggcgt caatttccat tgctaaatct
      781 atatcgtcat taacgataaa tggaacattg tattttttac aaagttcttt aatttggata
      841 gctagctcaa gtttttctaa gccttctaaa gcaccctcac ctttttctcg aaattgaaat
      901 aaggttatac caccttttaa ggcttcctca acgactgtat atagattttt tccttggcaa
      961 gtagtcgttc cacaaataaa atatagtttt agtaattctt tatgaaacat cttacttcac
     1021 tcttttgaat tcctttacat cttcatctgt aatctcgtat aaggcattta taaattcaac
     1081 tttaaatgtc ccaggaagat gtccatttgg atgtttttct gctatttctc cagcgatatt
     1141 gtaaaccaac attgctgttt ctaatgattt caattcttga cctttttcta gtccgataaa
     1201 gcttgctact acagctccta ataagcatcc tgtcccaatg actttcggca tcatagcact
     1261 accattatga atcgttacca cttctccatt aacagcaatg gcatccactt cacctgttac
     1321 tactattgga atattgaact tctcatttgc tgctagagca atttcgtcaa tattatctac
     1381 gcccgcacta tctactcctt tagatgccac atctattcct actaaagagg caatctcgcc
     1441 agcatttcct ctaatcgctg ctagtttata attgttgatt agatcatctg ctactttttt
     1501 tctatattct cctgctccac aggctacagg atctaaaact gctgggacat tatatttctc
     1561 cgcaattttc agagcagctt ggtataattt ccaattttca tctgtcaatg ttcctatgtt
     1621 tattaataaa ccaccagcat actttaacaa atcctctaaa tctgctggaa actcactcat
     1681 ggctggtgag gcgcccagtg ctactaatcc atttgctgtg aaatttttta ctacatcatt
     1741 ggttatacaa atgaccaatg gtgctttttc ttttaataat tttaaacttg tcatattgaa
     1801 atccttcctt ttcactttat acgatctact gatttcgatt tatttctatc tttcgttaag
     1861 aatttttttc atttacattg aatgatttat actcaatgaa aatcaaagag caaactagga
     1921 ggctaaccgc aggttgctca aaacactgct ttgagcctgt agataagact gacgaagtca
     1981 gctcaaaaca ctgttttgag gttgtggata gaactgacgt ggtttgaaga gattttcgaa
     2041 gagtcttacc tcatcaaatt tgtaaatatc atgagccttc tctagacatc gtaaccaata
     2101 tcaaaaaaag ctaattctaa agcgactgct tgattccagc gttgctgaag ttctgtcaaa
     2161 tcttctcgat ttttaccgac acgattgagt tcgtcaacca gaaattgaac ccactctgca
     2221 aagaaaggac ctctgtggag attgatccat tccgaatgaa tatagacttc aggtaaagcc
     2281 aaatctttag aaccccagtc taaatagaga ccttctgcaa tgaccagcat gaccaaaaga
     2341 tgggcatagt ctgatgaagc caccgccgaa tacattagat cctgaaaggc ttttgttaca
     2401 gggtgcaaag tcacttctag atagtcattc tctgctactt ttaactcttt aaaagccttt
     2461 tggaaataac catcttcatc tgcttcaaga aagcctagtt gcttggcaaa acgaagcttg
     2521 gattcaagtt tatctgcgtg agctacgcag gcacccagca tggataagaa ggcatcaaag
     2581 aagtgataat cttgaatcag atagtccttt aagaccttat tctcaattgt ccccgcaaaa
     2641 agttccttaa caaaacgatg attgattgca gcctgccaat ccttctgact gctttttaat
     2701 aattctccaa cagtcaaacc tggctgaaat gcatagtctt gtgtttccat atttacttct
     2761 cctctcttta cttgttagta attaataaaa caccaagaaa tatcaagcaa aatcgtaatt
     2821 ccacttgatc cttttaaaac acatcgagag tatttgcaga gagctaacta aacaagccta
     2881 tccagtttat ataaacaaaa aactccaatt acaatcaaga attagagttg acttacaaga
     2941 ttagatcgtt catttcgcca tacgaaaaaa cgtttcacat ttcccttcgc cagtcttaac
     3001 tgtatcaggt tcaatgggta tcatctcagc ttaaagcacc ccaaatgtct ctattattta
     3061 attactgaac cagtatagca aaaaatgaaa gccctagcaa gatatttgac cgaaaaatat
     3121 ctttatatag tagattgaaa ctagaatagt acacctctac ttctaaaaca ttgttagaaa
     3181 tcgatttgac tgtcctgatt gatttgtcct attcttattt catttcacta tagttttcga
     3241 tagcaattta ttcttccaat acacgaagaa aaacctccac attcagtgga ggcaatctgt
     3301 tttatcaata caattttaag tcacgagggt caactgggaa ggttgggttg tatggattgt
     3361 gacggagctt aaagtgtttg acatcttcaa tggtctgagc tccagacaat tgcataactg
     3421 tcttcaattc cgcattcaag tgttcaaaga cttgacgcac accgacacta ccaccgagag
     3481 ctaagccata aataacaggg cgaccaatag ctaccaagtc tgctcctgaa gccaaggctt
     3541 taaagacgtg ttgaccacga cgaacaccag agtcaaagac aatcggcaca cgtctatcaa
     3601 ctgcttctgc cacttcttga agcgagtcaa aggcagctgg tccaccgtcg atttgacgac
     3661 caccgtggtt ggttacccag ataccagaag ctcctgcagc aagtgaacgt tcaacgtcct
     3721 cacggcattg tggtcccttg acatacacag gaagaccaga gtattcagcg ataaattcta
     3781 catcgcgtgg agacaagcgt tgtttagctg atttgtaaac aaagtccatt gatttaccag
     3841 caccttctgg caggtattct tcaacaatcg gcatgccaac tgggaagaca aaaccattac
     3901 gcttatccac ttcacgattc ccccctacag tagcatctgc cgtcaagaca atcgctttat
     3961 aaccttcagc cttcacacgg tccatgatgt ggcggttgat accgtcatcc ttactaaagt
     4021 aaaattggaa ccaatggggt gtcccttgaa gggcttcaga aatctctgga aggtcaacag
     4081 tagagtaaga gctggttgta taaagagaac caaactcatg cacaccacgc gcagtcgcca
     4141 cttccccctg ttcatttgcc aatttatgag ccgcaacagg cgccataatg attggtgaag
     4201 atagtttttc acctgcaaat tcaatctctg tacttggatt ttcaacatcg caaagtgtat
     4261 gaggaacgat gagtttgtgg ttaaaggcgc ggatattctc tcttaaagtg aaagtatctt
     4321 ccgccccact agcgatatag ccaaatgctg ctttaggaat aacttgttgc gccattggct
     4381 ccaaatcata ggtattgatg aagtctacat gaccttctgc attgcttgtt ttatatgaca
     4441 taaaatgccc tccttgatta agtaagcgtt tgctttttac tacacaacta taataactct
     4501 tttttcaatc attttcaaga gttttgctta aaaaccatct tattttttca tacaatatac
     4561 tagccctact ttccttaaac tctaaacctt agtctatatt aagtgaatcg ttgagatttt
     4621 ttgctgccag gcatttgaac tactttttta tttgcggatt ctatctacta atactataaa
     4681 aaaaacaagt gaataagaca ccagaacatc ctctaatagg acctatggac ttatatcagt
     4741 cccatatata ctgtttaagc aagatactat cctagttgac gctaacttcc tatcccactt
     4801 attaattttt tatttatagt gaatctgaac aaatcaattg gggaatccaa gtcaatttct
     4861 agtacttttt gaacagtttc agcgtactat cgtaaaatga aataaaacat gcacaaattg
     4921 attagggaat ttaaaccaat ttctaacaat gtcttagaaa tcaaagtgta ctatttcaac
     4981 ttcaatatac tacacttcat tttctcctta aattcagtct ctttttgaat caaaaaatcc
     5041 tctggtaaga gccagagggt aagaattt
//
LOCUS       DAVLDI010000091         4889 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLDI010000091 DAVLDI010000000
VERSION     DAVLDI010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4889
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.092"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            75..671
                     /locus_tag="VXD01_002135"
                     /pseudo
     CDS             75..671
                     /locus_tag="VXD01_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            828..1196
                     /locus_tag="VXD01_002136"
     CDS             828..1196
                     /locus_tag="VXD01_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0602454.1"
                     /translation="MAVGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKAK
                     NMENAKKFIDFIISQEVQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIK
                     NKSDIVKKYNEVFTDIQSKQ"
     gene            1209..1595
                     /locus_tag="VXD01_002137"
     CDS             1209..1595
                     /locus_tag="VXD01_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602455.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGLVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYAD"
     gene            1602..1691
                     /locus_tag="VXD01_002138"
                     /pseudo
     CDS             1602..1691
                     /locus_tag="VXD01_002138"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1677..2300
                     /locus_tag="VXD01_002139"
     CDS             1677..2300
                     /locus_tag="VXD01_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602456.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIRAIQHEVGITTVYVTHDQEEAMAI
                     SDQIAAMKDGVIQQIGRPKELYHKPANEFVATFIGCTNIIPTNLEKRSDGAYIVFSDG
                     YALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASK
                     IQVSEESTFEEELQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            2290..3925
                     /locus_tag="VXD01_002140"
                     /pseudo
     CDS             2290..3925
                     /locus_tag="VXD01_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(4028..4720)
                     /locus_tag="VXD01_002141"
     CDS             complement(4028..4720)
                     /locus_tag="VXD01_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV0602457.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
BASE COUNT         1531 a         1040 c          850 g         1468 t
ORIGIN      
        1 aatagaattg taggttttaa aaacgcttac attgttttaa aataaactta aataacacaa
       61 cggaggtatc catcatgaaa aagaaatgga tgtattatgc tgcttgttct tctaatgaat
      121 ctgccgatga cagttcatct gataaaggag acggtggttc gctagtcgtt tattgaccaa
      181 actcagaagg cttaattgga gcaactattc ctgcctttga agaaaaatat ggtatcaaaa
      241 tagaactgat tcaagctggt actggagaac ttttcaaaaa actagagtca gaaaaagaag
      301 ttcctgtagc tgatgttatc tttggtggtt cttatacaca atatgctacc cacggagaac
      361 tctttgaaaa ctatatttca aaagaaaatg ataatgttat caaagaatat caaaacacaa
      421 ctggcttctc tactccttat acactagatg gtagtgtttt aatcgtccac cctgatttaa
      481 ctaaaggcat gaacatcgaa ggatatagcg accttctcaa acctgaacta aaaggaaaaa
      541 tcgcaactgc tgacccagca aactcttcta gcgcctttgc tcaattaaca aatatgctac
      601 aagctcaagg tggttacaaa gatgataagg cttggtctta tgtaaaagat cttttcacac
      661 ttattgatgg tatagtaaaa tgaaataaga acaggacaaa ttaatcagga cagtcaaatc
      721 gatttctaac aatgttttag aagtagaggt gtactattct agtttcaata cactataaaa
      781 tcggtttaag ttcatctggt gtctataaag cagtcgttga tggagaaatg gctgttggtc
      841 tctcttatga ggatccagca gttaaactct taaatgacgg agctaacatt aaagtagtct
      901 atccaaaaga aggaaccgtc ttcctacctg ctagtgctgc tatcgttaaa aaagctaaaa
      961 atatggaaaa tgccaagaaa tttatcgatt ttattatctc tcaagaagta caagatacac
     1021 ttggtacaac cactactaac cgtcctgttc gtaaaaatgc taaaacaagc gaaaacatga
     1081 aaccaattga caaaatcaaa acactcactg aagattatga ttatgtcatc aagaataaat
     1141 cagatatcgt taagaaatac aacgaagtct ttacagatat ccaatctaaa cagtaaaaga
     1201 ggttcactat gagtgagatc gaaattatta acgccaaaaa aatctaccac gatgtccctg
     1261 ttattgagaa tttgaacatt acaattccaa aaggaagtct ctttaccctt cttggagctt
     1321 caggatgtgg gaaaacgacc cttcttcgta tgattgcagg tttcaacagt atcaaagatg
     1381 gagaatttta cttcgatgat acaaaaatca ataatatgga acccagcaaa cgcaatatcg
     1441 ggctggtttt ccaaaactac gctattttcc cacatttgac tgtccgagac aacgttgctt
     1501 ttggtcttat gcaaaagaag gttccaaaag aagaattgat tcaacagacc aacaagtatc
     1561 ttgaactcat gcaaattgct caatatgcgg attgaaagcc cgataaactc agtggtggac
     1621 aacaacaacg tgtcaccttg gcatgcgcct tagcggttaa tccaagtgtt ctcctcatgg
     1681 acgagccact tagtaatctg gaggccaaac ttcgcttgga tatgcgtcaa gccatccgag
     1741 caatccaaca cgaagtggga attacaactg tttatgtaac ccacgaccaa gaagaagcca
     1801 tggctatttc agaccaaatt gctgctatga aagatggggt gatccaacaa atcggccgac
     1861 caaaagaact ctatcataaa ccagctaatg agtttgtggc aacctttatc ggatgcacaa
     1921 atattatccc tactaatctt gaaaaacgga gcgacggcgc ttatatcgtc ttttcagatg
     1981 gctatgccct tcgaatgcca gctcttgatc aggttgagga gcaagctatt catgtaagca
     2041 ttcgtcccga agagtttatc aaagatgaat ctggagatat tgaaggaact attagcgata
     2101 gcgtctatct tggactaaat acggagtatt tcattgagac aggttttgcc tcaaaaattc
     2161 aagttagtga agaatcaact tttgaagaag aactacaaaa aggcaatcgt attcgtctac
     2221 gaatcaatac gcaaaaatta aacatctttt ctgcagatgg ttcccaaaac ctgataaaag
     2281 gagtcaacca tggaatgtaa aaaactaaat atttggacaa cctcctcttt cttcatcttt
     2341 cttacctatc ttgtctttct cgtttatcct atcgttaccg tgctcaagca agcacttata
     2401 catgaaggac aattctcact agctaatttt gtcactttct ttagtaaagt ctactactct
     2461 gagacactag tcaacagttt caaggtttcc attaccgcta ctgtcacttc cttagttgta
     2521 ggaaccctat tagcttatct cttctctatg tatgacttca aggggaagaa atttctacaa
     2581 atattgatta tcattgcttc catgtcagct cctttcgtag gagcctactc ctgggttctc
     2641 ttgctaggac gaaatggggt catcactaaa tttttgacaa atgcccttca tcttccagct
     2701 atcgatattt atggattcaa aggaattgta cttgtcttta cactgcaact attcccactg
     2761 gtatttctat atgttgctgg aacaatgaac agtattgaca attctctact tgaagcagct
     2821 gaaagcatgg ggtccttcgg atttaaacct atcgtaacgg ttgttttacc tctcctagtt
     2881 ccaaccttac tagcagctcc ttgcttgtat ttatgagagc attctcagac tttggaacgc
     2941 ctatgttgat tggcgaagga tatcggactt tccctgtcct gatttatacc caatttatta
     3001 gcgaggttgg aggaaattct gcttttgcaa ttatggcgat tatcattgcc ttggcaattt
     3061 tccttatcca aaaacacatt gcaaaccgct acagtttcag catgaatctg ctccatccaa
     3121 ttgagcctaa aaaaactaca aaaggaaaaa tggctgccat ttatgcaaca gtctacggaa
     3181 ttatctttat ctctgtttta cctcaaatct acttaattta tacctctttc ctaaaaacat
     3241 caggtatggt atttgttaaa ggttattctc caaacagtta caaggtagct ttcaatcgta
     3301 tgggatctgc tattttcaat accattcgta tccctttgat tgccttagtt ctagttgttc
     3361 tatttgcgac atttatctcc tacctagccg ttagaaaacg gaatttgttt acaaacttaa
     3421 ttgacagcct cagtatggta ccttatattg taccaggaac cgttctaggg attgccttca
     3481 tttctctggt ctatttggaa gtggatttct tatgattaca gggactgctt tcatcttgat
     3541 tatgtctcta tctgtcagaa gattaccgta tactattcgc tcatctgttg ctagcttaca
     3601 acaaatagca ccaagtattg aagaagctgc tgaaagctta ggaagtagtc gtctcaatac
     3661 ctttgctaag attacaactc caatgatgct atctggtatc atttctggag ccatcttatc
     3721 ttgggtcaca atgatttcaa aactctctac ttctatcctc ctctacaatg tcaaaacaag
     3781 aacaatgact gtagctattt atacagaggt tctcagagga aattacggtg tagccgcagc
     3841 cttgtcaact atcctgactg ttctaacagt aggttccttg ctcttgttta tgaaaatctc
     3901 taaaagcaat agcattacac tttagttttc cacatcaaaa acagccgaaa ggagtaccct
     3961 cggctgtttt ttcttatctt gatatcctta tcaaatccct agctcatggc aagcaagtct
     4021 agactgatta aatagagcct tcttccatct tctcacgtcc tagctctcgg taactacggt
     4081 caccgacaac ttcaacccta aactgaccgt cctcatattc aagaatcgtc acgctaccat
     4141 tatctagacc atgcggatgc atgccattaa tcagataaac aatggttcca atagtcattc
     4201 catggctgac aacaagggcg ttacctccac cttgatcttc catttctttt gcaattattt
     4261 caaagccttc cttgattcgg ccactgagtt tttcccagcc ttcagcccaa ccagctgtat
     4321 cgacctctac caagccctca gccagttcag cataagacaa ttggtgaacg tggtccacat
     4381 taaagatacg aggaataatg cccatgaaaa gatcgccatc ataggctcca tcaaaactac
     4441 cgaaacacca ttctctgata cgcttgtcca tgcgataagg gattttcccc tgcaagccaa
     4501 gctcttcaag gataattccc atggtctgaa tggtacgacc agaatcactc gaataagcgc
     4561 gctcaaactg tagatcagat tctcgcaaac cgattcctaa ctcttgaatc cctcgttcac
     4621 cttcagcagt taagggagta tcgctccaac cttgcgcgcg accaatcgtg ttaaacatgg
     4681 tcttgccatg acgtaccaaa tacaatcgta cttttaccat tttccgtcct ccgtttgctt
     4741 ctattatatc atgaatgata aaataaaagc cacccataca ggcgactttt gaaggagatt
     4801 attatgaaaa agtttaggag ttcattaaat aaagatatta gatgaaaatc aaattcaaac
     4861 taattcagtg ttatctgttt caaataata
//
LOCUS       DAVLDI010000092         4886 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLDI010000092 DAVLDI010000000
VERSION     DAVLDI010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4886
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.093"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(63..188)
                     /gene="comC"
                     /locus_tag="VXD01_002142"
     CDS             complement(63..188)
                     /gene="comC"
                     /locus_tag="VXD01_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV0602458.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            complement(353..426)
                     /locus_tag="VXD01_002143"
     tRNA            complement(353..426)
                     /locus_tag="VXD01_002143"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(390..392),aa:Arg,seq:tct)
     gene            complement(470..949)
                     /gene="rlmH"
                     /locus_tag="VXD01_002144"
     CDS             complement(470..949)
                     /gene="rlmH"
                     /locus_tag="VXD01_002144"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV0602459.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            1132..2313
                     /locus_tag="VXD01_002145"
     CDS             1132..2313
                     /locus_tag="VXD01_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV0602460.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            2371..3129
                     /locus_tag="VXD01_002146"
     CDS             2371..3129
                     /locus_tag="VXD01_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV0602461.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            3342..4703
                     /gene="dnaA"
                     /locus_tag="VXD01_002147"
     CDS             3342..4703
                     /gene="dnaA"
                     /locus_tag="VXD01_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV0602462.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
BASE COUNT         1713 a          866 c          805 g         1502 t
ORIGIN      
        1 taaaaaatga acaataaccg tcccaaatcc aaataaatcc attactcttt ccccttattt
       61 cattactttt ttctttgtaa aataaaatca cggaagaatt ttgacaacct catctcccca
      121 cctttaatct tttgtaagtc tttttccttc aaagctacaa actgttccaa tttaactgtg
      181 tttttcataa taaaatctcc taaaatgttt tttcttgtaa gctaacttac aaaaaacatt
      241 atacaaaatg gaatttcgtt ttagataaaa ttctctcaac tgtcattttt ttctcccaaa
      301 gtgtactttt ttaagaaaaa agccgggaaa attcccagct ttgctattat attgatccca
      361 gcaggattcg aacctgcgac cgttcgctta gaaggcgaat gctctatcca gctgagctat
      421 gagacctaat acaattattc taccaaaaat tcaattaaaa gtcaattttc tatttatggt
      481 aggggaatcc ctgctgaatc gtaaaagcgc gatagatttg ttcaacaaga actagtctca
      541 ttaactgatg gggtaaggtt aggcgaccaa aactgacaga aagattggct ctatttttta
      601 cagatgatga caatcctaaa cttcccccaa taataaaagt aagagtagaa aatcctttta
      661 tagaagtttc ttctaactgc ttactaaatt cttctgagaa gaaagttttc ccttcaatgg
      721 ctaacacaat aacgaaatca cggtcagcaa tttttgataa aattctctga ccttctattt
      781 ctaaaatctt ttgattttct gattcactgg ccttatctgg tgttttttca tctgataact
      841 caatcatttc aaacttagca aatctagaaa ttcgttttga atactctgcg ataccatctt
      901 ttaaatactt ttctttcagt ttcccaactg ttacaacttt aattttcatg actctattct
      961 aacatattct ctattttttc acatcttatt cacaaaataa aaaatagatt tcaattaaga
     1021 aaatcacagt ttcaaaagag ttatccacag tttgtgtaaa acttttgtgt ttaagttata
     1081 attaagctag tcagtttata ctttcagtaa ttcaaacata tggaggcaaa tatgaaacat
     1141 ctaaaaacat tttacaaaaa atggtttcaa ttattagtcg ttatcgtcat tagctttttt
     1201 agtggagcct tgggtagttt ttcaataact caactaactc aaaaaagtag tgtaaacaac
     1261 tctaacaaca atagtactat tacacaaact gcctataaga acgaaaattc aacaacacag
     1321 gctgttaaca aagtaaaaga tgctgttgtt tctgttatta cttattcggc aaacagacaa
     1381 aatagcgtat ttggcaatga tgatactgac acagattctc agcgaatctc tagtgaagga
     1441 tctggagtta tttataaaaa gaatgataaa gaagcttaca tcgtcaccaa caatcacgtt
     1501 ataaatggcg ccagcaaagt agatattaga ttgtcagatg ggactaaagt acctggagaa
     1561 attgtcggag ctgacacttt ctctgatatt gctgtcgtca aaatctcttc agaaaaagtg
     1621 acaacagtag ctgagtttgg tgattctagt aagttaactg taggagaaac tgctattgcc
     1681 atcggtagcc cgttaggttc tgaatatgca aatactgtca ctcaaggtat cgtatccagt
     1741 ctcaatagaa atgtatcctt aagatcggaa gatggacaag ctatttctac aaaagccatc
     1801 caaactgata ctgctattaa cccaggtaac tctggcggcc cactgatcaa tattcaaggg
     1861 caggttatcg gaattacctc aagtaaaatt gctacaaatg gaggaacatc tgtagaaggt
     1921 cttggtttcg caattcctgc aaatgatgct atcaatatta ttgaacagtt agaaaaaaac
     1981 ggaaaagtga cgcgtccagc tttgggaatc cagatggtta atttatctaa tgtgagtaca
     2041 agcgacatca gaagactcaa tattccaagt aatgttacat ctggtgtagt tgttcgttcg
     2101 gtacaaagta atatgcctgc caatggtcac cttgaaaaat acgatgtaat tacaaaagta
     2161 gatgacaaag agattgcttc atcaacagac ttacaaagtg ctctttacaa ccattctatc
     2221 ggagacacca ttaagataac ctactatcgt aacgggaaag aagaaactac ctctatcaaa
     2281 cttaacaaga gttcaggtga tttagaatct tgattgacat ctatgtaaag aaagctttac
     2341 ataagagaaa agatgtgtta gtgtagaatc atggaaaaat ttgaaatgat ttctatcaca
     2401 gatatacaaa aaaatcccta tcaaccccga aaagaatttg atagagaaaa actagatgaa
     2461 ctagcacagt ctatcaaaga aaatggggtc attcaaccga ttattgttcg tcaatctcct
     2521 gttattggtt atgaaatcct tgcaggagag agacgctatc gggcttcact tttagctggt
     2581 ctacggtcta tcccagctgt tgttaaacag atttcagacc aagagatgat ggtccagtcc
     2641 attattgaaa atttacagag agaaaattta aacccaatag aagaagcacg cgcctatgaa
     2701 tctctcgtag agaaaggatt cacccatgct gaaattgcag ataagatggg caagtctcgt
     2761 ccatatatca gcaactccat tcgtttactt tccttgccag aacagattct ctcagaagta
     2821 gaaaatggca aactatcaca agcccatgcg cgttccctag ttgggttaaa taaggaacaa
     2881 caagactatt tctttcaacg gattatagaa gaagatattt ctgtaaggaa gttagaaact
     2941 cttctgacag agaaaaaaca aaagaaacag caaaaaacta atcatttcat acaaaatgaa
     3001 gaaaaacagt taagaaaact actcggttta gatgtagaaa ttaaactatc taaaaaagac
     3061 agtggaaaaa tcattatttc tttttcaaat caagaagaat atagtagaat tatcaacagc
     3121 ctgaaataag gctgttcttt tattttttta tctcacaagg ttatccacta tgtttttcga
     3181 taaaaagctt aataaatcaa taatttcttc ttttatcccc aacctgtgga taaagtttgg
     3241 taacattgtg gattattttt cacagcttgt ggaaaattct tgctatctat ggtaaaatat
     3301 ctctagtatt aaacttttaa atagtaaagg aggagaaagg attgaaagaa aaacaatttt
     3361 ggaatcgtat attagaattt gcacaagaaa gactgactcg atccatgtat gatttctatg
     3421 ctattcaagc tgaactcatc aaggtagagg aaaatgttgc cactatattt ctacctcgct
     3481 ctgaaatgga aatggtctgg gaaaaacaac taaaagatat tattgtagta gctggttttg
     3541 aaatttatga cgctgaaata actccccact atattttcac caaacctcaa gatacgacta
     3601 gctcacaagt tgaagaagct acaaatttaa ctctttatga ctatagtcca aagttagtat
     3661 ctattcctta ttcagatacg ggattaaaag aaaagtatac ctttgataat tttattcaag
     3721 gggatggaaa tgtttgggct gtatcagccg ctttagctgt ctctgaagat ttggctctga
     3781 cctataaccc tctttttatc tatggaggac caggccttgg taagactcac ttattaaacg
     3841 ctattggaaa tgaaattcta aaaaatattc ctaatgcgcg tgttaaatat atccctgccg
     3901 aaagctttat taatgacttt cttgatcacc taagacttgg ggaaatggaa aagtttaaaa
     3961 agacctatcg tagtcttgat cttttgttaa tcgatgatat acagtcactc agcggaaaaa
     4021 aagtcgcaac tcaggaagaa tttttcaata cctttaacgc ccttcatgac aagcaaaaac
     4081 agattgtcct aacgagtgat cgtagtccaa aacatctaga agggctcgag gagaggcttg
     4141 tcacgcgttt tagttgggga ttgacacaaa ctatcacacc ccctgacttt gaaacacgta
     4201 ttgccatttt acaaagtaag acggaacatt taggctacaa tttccaaagt gatactctag
     4261 aatacctagc tgggcaattt gattcaaatg ttcgagatct tgagggagcc atcaacgaca
     4321 tcactttaat tgccagagta aaaaaaatca aggatatcac tattgatatt gctgcagaag
     4381 ccattagagc ccgcaaacaa gatgttagcc aaatgctcgt catcccaatt gataaaatcc
     4441 aaactgaagt tggtaacttt tatggtgtta gtatcaaaga aatgaaggga agtagacgcc
     4501 ttcaaaatat tgttttggcc cgtcaagtag ccatgtattt atctagagaa ctaacagata
     4561 atagtcttcc aaaaattggg aaggaatttg ggggaaaaga tcataccaca gtcattcatg
     4621 cccatgccaa aataaaatct ttgattgatc aagacgataa tttacgttta gaaattgaat
     4681 caatcaaaaa gaaaatcaaa taatttgtgg ataactttta gttttttatc ttttttatcc
     4741 acatttttta aacaagctaa aaaacttgat atgacttgtt taaaggctgt tttccacaga
     4801 tttcacagac tctattatta ctattatctt tctaatacta aaaataaata aaggagaatc
     4861 catgattcat ttttcaatta ataaaa
//
LOCUS       DAVLDI010000093         4860 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLDI010000093 DAVLDI010000000
VERSION     DAVLDI010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4860
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.094"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(183..1598)
                     /locus_tag="VXD01_002148"
     CDS             complement(183..1598)
                     /locus_tag="VXD01_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV0602463.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     EEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1611..3449)
                     /locus_tag="VXD01_002149"
     CDS             complement(1611..3449)
                     /locus_tag="VXD01_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV0602464.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3467..4306)
                     /locus_tag="VXD01_002150"
     CDS             complement(3467..4306)
                     /locus_tag="VXD01_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV0602465.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4606..4788)
                     /locus_tag="VXD01_002151"
     CDS             complement(4606..4788)
                     /locus_tag="VXD01_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV0602466.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIASELVAGLR"
BASE COUNT         1627 a          943 c          633 g         1657 t
ORIGIN      
        1 ctatatataa ccaatctatc ctaagtttac tatttataat cggctctctg taacaaaatt
       61 aaattaatta atccccctat aaaataaaga ggtttagaat ttgatgtctt ccaaacctct
      121 ttatttcata tttaatgaga tgttgcctta accgtgataa tatctaatca tcaataaaca
      181 aactatttga ataaggattc tccatttgat tcaatcactc ctttatacca agtaaaggac
      241 attttcttat atcgattgaa tgtgccattt ccatcatcat ttcgatcaac ataaatgaga
      301 ccgtaccttt tagaaagttg tgcagtggac atagaaacgc agtcaataca tccccaagat
      361 gtatagccca taatttccac accatcttgt agagcttcag ctacttgcaa taaatgttct
      421 tccatatact gaattctata atcatcttgg actgttaagt tattaaattc atcttttatt
      481 agttgatctt tagcacctaa tccgttttcc actataaata atggaatttg ataacggtca
      541 taatatctat ttaaaattat acgtagtcca attggatcaa tttgccatcc ccactcagaa
      601 gactctaaat aaggatttac taagccacca ataatattcc cttctcctga attatactgt
      661 gttggaagag cagattgagt cacactcatg taatagctaa aggataaaaa atctacagta
      721 taatttttta ataactctgc atcttcagct gcaaactcta tgttaatgtc atgttcctta
      781 aaatatcttt ttgcataatt cggataataa cctctaacat gcacatctga aaatagataa
      841 tttagattct catactcatg agtcgcccat acatcttttg gatttggagt cattggataa
      901 gctggcatag ctaataccat acaccccacc ttaaactctg aattaatctc acgagcaatt
      961 tttgtaacca aactcgaggc gactaattca tgatgtatag cttgatataa ttcttgtttc
     1021 gaaagattct ccttaggtat atctattcct ccactagtaa acggtaattc caaaacagag
     1081 tttacttcgt taaatgtaag ccaatattta actttatctt tatacctttc taaaactgtt
     1141 cgagcaaatt tttcataaaa atgaatcatt ctcctatcaa tccatccatg atattttctt
     1201 gctaaatata atggagtctc atagtgtgaa agagttacaa gtggttctat cccgtgagca
     1261 tgtagttcat caaataattc atcataatat ttcaacccag cttcgttagg ttcttcttca
     1321 tctccttttg gaaaaattct actccatgca atagaagtac gaaaaacatt aaagcccatt
     1381 tcagaaaaca aggatatatc ttccttatat ttatgataaa aatcaatacc taacaatttt
     1441 aagttatctt ctgtaggatt ttctgttgct tctcctaatc cacctttggg taacacatcc
     1501 tgaactgata atcccttacc atcttcatta tatgctccct ctacttgatt agctgcaacc
     1561 gctccacccc aaagaaaatc atctggaaaa atggtcataa ctttcctcca ttataatatt
     1621 accagtaatt ccttagaatg ctcgattgtc tgattattag gtaatactaa tacatctaga
     1681 aaatcattgg tattcgttac aattactggt gtaactgttt cgtagccttt agtcttgatt
     1741 aaattcaagt ccatttcaaa aatcaactga tttttgaaaa ctctgtctcc ttcttctaca
     1801 tgactaataa aaccttgacc ttttagctca acagtatcta atccaatatg aattagtaac
     1861 tcaacaccct catcactctt caatccaatt gcgtgcttag tcggaaaaat atttgtaatt
     1921 ttcccatcaa atggtgcata aaccttacct tcacttggga taatcgctac tccgtctcca
     1981 attagtttat ctgaaaatgt tttatcctgg acatcgctta acggaatgat ttctcctgat
     2041 ataggagaaa atatcatttt tttatttgaa actccagctt caacttctaa attgctagaa
     2101 ctctcttctt catcgattcc aaatatataa gctaatacaa aggtaataac aaccgaaatg
     2161 accgccacaa ttaaagcatt tacaatattt gatggcacat cagaataaat aaattgaggc
     2221 aacgctatca aagatgggac agcaaataga tatgctttaa cactagtaag acctgcaaat
     2281 aatcccgcta atccaccacc aatcatagct gcataaagcg gttttttata ttttaaagtc
     2341 acaccatata atgcaggttc ggtaatccct gcaagtaagg ctgagaaacc tgctgcaaaa
     2401 gcaatttgtt ttgtattatt atttttactc tttaatgcaa cagccatcga agcagcccct
     2461 tgagctaagt ttgaccctaa cattgctgga agaattaata cgtctggagt agcaatagat
     2521 gccgccaaaa aaataggtgc aaaagcccaa tgcattccag tcataacaat aaatggcata
     2581 atagcaccaa gaatagctaa tgtaagccat ccagctacac catacatttg cccaactaga
     2641 tttgataatc cttcaccaac aattactcca ataggtccga ctacaactaa ggcaatacag
     2701 cttgatacta ataatactag cgtaggttgc aaaaaactct tagtaatagc tggtgttaat
     2761 ttagcaatta ttttttcaat atatttcatc aaccaaacca taataagaat tggaacgact
     2821 gatgaaccat aactagctgg tgtcacaggt gcaccaaata aactaagagg attccctgat
     2881 tgcaccattt gaacaaaatt tggatggaga agtacacctg ctacagacat agctaatgta
     2941 gatgttactt ttaatttttg tgatgcagaa taagctaata acagcggtaa gaaataatat
     3001 ggagcatccc caaaaaatgt caaaaaagca atagtctgag aatctgattg caatatacca
     3061 agcattggta aaatgattac caagactttc aacatacctc cccctaacat tgctggaatg
     3121 attggagtca tggaaccagc gatatactca atgattcttt ctaaaatatt ccctttgtgc
     3181 ccttgaacaa ctgaatcgga ttcaaaattg ccaagtttaa cgaattcttt ataataatta
     3241 gctacatcat taccaagtat aatttgatat tgtccattct ttttcataat acctattaca
     3301 cctggtatct tcttcacatc atcatcattg actaaatttt catcttttaa ttctaatctt
     3361 aaacgtgtta cacaatgggt aactctattg acattttttt cacctccaat tacatcgagg
     3421 attttttgta ccgtatcttt ataactcatg gtattctcct attctattaa tctaaatttt
     3481 ttgttaagcg acgaatatga gccatcaaat aaactaattc actagaagtc agcaaataat
     3541 tgtactccgt ttgtataaac attgccacct gttcaccaca ttcatattct ctaggatatt
     3601 tatttttcat taatgctaac aagtcttcat catcatcgtc acaataagtt gtattttcaa
     3661 ccaagcgatg ggcaaataat tttatatgag ttatgaatct ataataatca atagaatctt
     3721 ggttaaactc agtacaatag aaatcttgaa tgattttctc aattcccata attatttcag
     3781 tgattttata cgactcttga aaattatttt ctaaattagc attaacaaaa tgtagcgcta
     3841 tgaatgcagc ttcgtcaatt ggaagttcaa tacctaactc tttttttatt atttgtaaag
     3901 cccttttccc aagttcaaat tcttctttat aatatttcga gatttcccag cgtaggggat
     3961 tcgaaataat aactccttct ttataacgtt ctatgctcga agaaatatga tccgttaaat
     4021 taatatagat aatttcatca aaattattac ccaatgttat tttacctagg ttaattattt
     4081 tttcggtgat gtacaccaac tccaaaggaa cgttaataaa catctctgta aaacgggtca
     4141 tattatctct atttttgaga aaaaaacttt tctcaatatc aattggattt actttatctc
     4201 cagtttttct tccaaaagct attccccttc caaaaagaag aatatcgata tcttttttac
     4261 tttgcgcaat tacggcattg tggtttagta ttcgttttat gatcataaaa tttccctttt
     4321 aaaataaaag gaacctactt aaaaacatca agaaacttct tccgatgtga ttaaataggt
     4381 tcctgctcac ttgtattagt gataacatcc ttttatttca atttttaatg gtgacatgaa
     4441 gcttaaatca ttaataactc tgtaaccatt ttcattttaa gatatttcaa tctatttgtc
     4501 aagtacttat agaaattttt ttattttgtg tgattcgaat gtgataatga caacagtctc
     4561 actaaagaaa tgaaaatcat acatagaaat ttttaaaaat tttctctatc gtaaacctgc
     4621 cactagttca gaagctatac tagctgattc caaacgtaat atggtcatct catctacctt
     4681 ccctaataat ggcattgcac cataccaaac aatagtctta ttcaccaaaa gaataggcgt
     4741 tactattttt gattgagtaa aagacacttt aattttctgg ctcttcaact gtgaactaca
     4801 ccccaaaagt tagacagaaa aaatctaact tttggggtgt ttttattatg aaattaactt
//
LOCUS       DAVLDI010000094         4386 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLDI010000094 DAVLDI010000000
VERSION     DAVLDI010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4386
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.095"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            529..885
                     /locus_tag="VXD01_002152"
     CDS             529..885
                     /locus_tag="VXD01_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602467.1"
                     /translation="MKRDVRDIRKQFRLTEAEEKQILALMRERGETNFSDFLRKSLLS
                     SDLQKQMETWFALWQSQKLEQISRDVHEVLILAQSERQVTQEHVSILLTCVQELIQEV
                     ANTIPLSKEFREKYMR"
     gene            890..1255
                     /locus_tag="VXD01_002153"
     CDS             890..1255
                     /locus_tag="VXD01_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV0602468.1"
                     /translation="MEHRYRTNLKKVFLSDSELNQLNINIDQSGCKSFSEYARRTLLD
                     PGMNFITIDTNGYQDLVFELKRIGNNINQIARSVNQSQLISGEELQELKKGIGELIKE
                     VDKEFNLQAQKLKEFHGHH"
     gene            1242..3065
                     /locus_tag="VXD01_002154"
     CDS             1242..3065
                     /locus_tag="VXD01_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV0602469.1"
                     /translation="MVITKHFAIHGKSYRRKLIKYILNPEKTNNLALVSDYGMKNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRMEENQRKIHAHHIIQSFSPEDHLTPEQINR
                     IGYETVKELTGGKFRFIVATHVDKDHLHNHIIINSVDSNSDKKLKWDYKVERNLRMIS
                     DRFSKIAGAKIIENRYSHQRYEVYRKTNHKYELKQRLYFLMEHSRDFEDFKKNAPLLH
                     VEMDFRHKHATFFITDSTMKQVVRGKQLNRKQPYTEEFFKNYFAKREIESLMEFLLLK
                     VENMDDLLQKAKLFGLTINPKQKHVSFQFAGVEVKETELDQKNLYDVEFFQDYFKNRK
                     DWQAPETEDFVQLYQEEKLSKEKELPSDEKFWESYQEFKSNRDAVHEFEVELSLNQIE
                     KVVDDGIYVKVKFGIRQEGLIFVPNMQLDMEEDKVKVFIRETSSYYVYHKDAAEKNCY
                     MKGRTLIRQFSYENQTIPLRRKATVDMIKEKIAEVDALIELEVENQSYVTIKDELVHE
                     LAASELRINELQERMSTLNQVAEYLLASVESKQEMKLNLSKLNITENISANIVEKKLK
                     SLGNQLELERGRYEKMVVRLDKFINRLNTGLSKGDGIDFQK"
     gene            3179..4045
                     /locus_tag="VXD01_002155"
     CDS             3179..4045
                     /locus_tag="VXD01_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV0602470.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEEVNELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKFYMEWIKSLIDFYFYGQKEEAITRLENMLPQLNVSDLNYLQVSNTLFN
                     FYYDIEDLERFNEIRDKLEHQVNQLNLNTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKEYRTTYLLADLYLLMGSVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYFADITE"
BASE COUNT         1563 a          656 c          879 g         1288 t
ORIGIN      
        1 ttatcaattc caaagatgat ataacaatct tcgtgatgtg atgtattgac aaaatttaag
       61 atatcacgca ccaattcagt ttttgaatga tgccattttt gtttaaaatc atgaaactca
      121 tcttcgggtg tattcaatag taagtgtatt tgatctagac tcagcatttt tatttctcca
      181 aatattagtt tacagaaatt ttatcataga atcagagaaa gtcaatcata actatattag
      241 ctgtgatacc tttttcaaat cttccctgtt atcctaatat cattcataga aaatcaattt
      301 ttgattttct atgggggttt gggggcgaag tcaccaagtt atcttatcgt tggctgtcaa
      361 aactagaaag ttttgatagg ctggcgatat gatttttggg atattgtgga cacaatatct
      421 gagctcgcaa agccttacaa gaatgaaaat cagttgttgg aaaagtgtac tgacattgta
      481 tggtagctca cattgtcagt acaagtattt tggaaaggaa gtagcagtat gaaacgagat
      541 gtgcgtgata ttcggaaaca atttcgttta acagaagcag aagaaaagca aattctagct
      601 ttgatgagag agcggggaga gactaatttc tctgattttc ttcgtaaaag tttactttcc
      661 tctgatttac aaaaacagat ggagacatgg tttgccctct ggcaatccca aaaactagaa
      721 caaatcagtc gtgacgttca tgaagtttta atcttggcac agtcagaacg tcaagtcacc
      781 caagagcatg tatctattct cttaacgtgc gtgcaggaat tgattcaaga ggttgcaaac
      841 accatacccc tcagtaaaga atttcgtgag aagtacatga ggtaagcaca tggaacatcg
      901 ttaccgaacc aatctcaaga aagtgttttt gtctgatagt gagttgaacc aactaaatat
      961 aaatatcgat caaagtggtt gtaaatcctt ttctgaatat gcgagacgaa ctctactcga
     1021 tcctggtatg aattttatca cgattgacac aaacggttac caagatttag tgtttgagtt
     1081 aaagaggatt ggcaataata tcaaccagat tgctcgaagt gttaatcaat ctcagttaat
     1141 ttctggtgaa gaattgcagg agttgaaaaa aggaattggt gaattgataa aagaagttga
     1201 taaggaattt aatctgcaag cgcagaagct aaaggagttc catggtcatc actaaacact
     1261 ttgccattca cggaaagagt taccgcagaa agcttatcaa gtacattctc aatcctgaga
     1321 aaaccaataa tcttgccttg gtgtcggact atggcatgaa gaattttctg gactttccta
     1381 gctatgagga aatggtgcag atgtatcatg aaaatttcat cagcaacgat acgctttacg
     1441 attttcgcca cgacaggatg gaagaaaatc aacgaaaaat acacgctcac cacatcattc
     1501 agtctttctc gccagaggat catctcactc ctgaacaaat caatcggata ggttatgaga
     1561 ctgtgaagga attaactggt ggcaaatttc gttttatcgt tgcgacccat gttgataaag
     1621 accacctgca caatcacatc attatcaatt cagtagatag caattctgac aaaaagctca
     1681 agtgggacta caaggtggag cgaaatcttc gcatgatttc tgaccgtttt tctaaaatcg
     1741 caggtgctaa aatcattgag aaccgctatt ctcaccagcg gtatgaagtc tatcgtaaga
     1801 ctaatcacaa gtatgaactc aagcagcgac tctatttttt gatggaacat tctagggact
     1861 ttgaggattt caaaaagaat gctccgctac tacatgtgga gatggatttc cgtcacaagc
     1921 atgccacctt ttttattacg gactcaacta tgaaacaggt ggtgcgtggc aagcaactca
     1981 atcgcaagca gccttacaca gaagaatttt ttaagaacta ctttgccaaa agagaaatag
     2041 aaagtctcat ggaattttta ttgctgaaag ttgagaatat ggatgattta cttcagaaag
     2101 caaaactttt tggactaact atcaatccta aacaaaagca tgtttctttt caatttgcag
     2161 gagtggaggt aaaggagaca gagctagacc agaaaaatct ttatgatgta gagtttttcc
     2221 aagattattt taaaaataga aaagattggc aagctccaga aactgaggat ttcgttcaac
     2281 tttatcaaga agaaaagtta tccaaagaaa aagaacttcc aagcgatgag aagttctggg
     2341 agtcctatca agagttcaag agtaacagag atgccgttca tgaatttgag gtggagttgt
     2401 cactcaatca aattgaaaaa gtagtggatg atggaattta cgtcaaggtc aagtttggta
     2461 ttcgtcagga gggacttatc tttgtgccga acatgcagct tgatatggaa gaggataagg
     2521 tgaaggtttt catcagggaa accagctcct actatgtcta ccacaaagac gctgccgaga
     2581 aaaattgtta tatgaaaggt cgaaccttaa ttagacagtt cagctatgaa aatcaaacca
     2641 ttccattacg cagaaaagcg acagtcgata tgattaaaga gaagattgcg gaagtggatg
     2701 ctttgattga actggaagta gaaaatcaat cttatgtcac gattaaagat gagttagtgc
     2761 atgaactagc agcgtctgaa ttgagaatca atgagttgca agaacgaatg tcaaccttga
     2821 atcaagtagc agaatatcta ctggcttcag ttgaaagtaa gcaagaaatg aaattaaatc
     2881 tttcaaaact gaatataact gagaatatca gtgctaatat tgttgagaaa aaattgaaga
     2941 gcctggggaa tcaactggaa ttggaaaggg gcaggtatga aaagatggta gtcaggctag
     3001 ataaatttat aaatcgctta aatacaggac tttcaaaagg agatgggata gattttcaaa
     3061 aataggaatc tagccaataa ttatatacaa tgtgtatctt ttgtaaaata tatttgaaat
     3121 ttagatttaa tcatgttaca attaacattg aaatcaaata gaaaaggaag atgcaaacgt
     3181 gggtacacta ttagcaacaa gattaaaaaa tagacgaaaa gaattaaaaa tgtctcagcg
     3241 agaattagct gagggtatct gtaaacaggg gcaaattagt cgattagaga gtggagagtt
     3301 cacccctgga gcggattttt tacatgccct tgctaagaaa ttaaaagtta gtatggacta
     3361 cttttttgat gagcaggttg tagaggaagt caatgagtta tcagagttta agaagttagc
     3421 acagacattt atcacaaatc gtaattatga atctttaaaa tatatatatg aattggaaaa
     3481 tgtaaaagcc catcgcttat ctctagcaga taaattttac atggaatgga taaagtctct
     3541 tatagatttt tatttttatg gacagaaaga agaggcaatt acacgattag agaatatgct
     3601 acctcagtta aatgtatctg atttgaacta ccttcaagtt tcaaacactc tattcaattt
     3661 ttattatgat attgaagatt tagaacgttt taatgagatt agagacaagc tagagcatca
     3721 agtgaatcag cttaatttaa acacaattga agagttagaa ctatcaatta agttcaatta
     3781 taacgtttgt cgatacctat ggttacagaa aaatattgaa gaagctatta cgaaaatcac
     3841 agctacgata aagcaatgta aggagtacag gacaacttat ctattagctg atttgtattt
     3901 attgatggga agtgtaagtg aaaatttttc ttctaaaagt tcagtaaaag aatattttga
     3961 gactgctcat tttctctaca aacttgagga aaacatgtca atggctttga aagtcgaaca
     4021 ttattttgca gatataacag aataaggaat acggtgttct agtgagcatc gttttttaaa
     4081 tctaatttga atacaaaaaa gtattaaata aaaaaaaata aaaaaagatt ataaaaatac
     4141 ttgacaagct aattttgaag tgataaaata aatgcaagaa aacgaaagga gaggtatatg
     4201 agaagtttgt ttaggaaaat tgttgctttg ttagtcatag gattaatcct attagggact
     4261 gctggaggaa ctcaagttca taagatggct agagggattg atccaggtcc tgcgaatggt
     4321 atttatagat aggagattat agtcacttaa aaatcaaaaa attataaaat ttttgtttta
     4381 cttaaa
//
LOCUS       DAVLDI010000095         4088 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLDI010000095 DAVLDI010000000
VERSION     DAVLDI010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.096"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            137..1372
                     /locus_tag="VXD01_002156"
     CDS             137..1372
                     /locus_tag="VXD01_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602471.1"
                     /translation="MKLYRCWYQTFVSDEASEETPLAERGEKEYIVKSSRMTALCYAE
                     SKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRYKLVSKLEFSP
                     NLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVITRTWANNVRLS
                     AITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHEGDTLNENYDK
                     VDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPIIEDDKIWFYY
                     MGGNGNHIGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYDDEIYILADIP
                     ENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLGNSPVAFKFEI
                     ENAKLYGIEGSIQQHYLKY"
     gene            1441..3018
                     /locus_tag="VXD01_002157"
     CDS             1441..3018
                     /locus_tag="VXD01_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0602472.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            3078..>4088
                     /locus_tag="VXD01_002158"
     CDS             3078..>4088
                     /locus_tag="VXD01_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0602473.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HAN"
BASE COUNT         1462 a          549 c          801 g         1276 t
ORIGIN      
        1 tcaattaaaa ttaaataagc taaaaaaaga tactgaaaac aatccactat ttggtgaaga
       61 gtattttgcc gaaaatccta aattatggga agttcgtttt gataattcat atccaaacgt
      121 tatctatgat aaagaattga aattatatag atgttggtat caaacatttg ttagtgatga
      181 agcaagcgaa gagactcctt tagcagaacg tggagagaag gaatacattg tcaagtcatc
      241 tagaatgaca gcactttgct atgctgaaag taaagatgga gtaaaatggg aaaaaccaaa
      301 tctcaatcta gtaaaattta aaggttcaaa agataataat attgttctga tgcatgcaca
      361 cggtgcaggt atcatgctag atgaacagga gttggatcct aagaaacgat ataaattagt
      421 ttcaaaatta gaattttctc cgaatcttca ttacatggtt gttgtttttt cagaagacgg
      481 tattcatttt gacgaaccta ttccatggaa aaaatggaat cctgcagcag atagtcataa
      541 ttttccattt agagatccaa aaactggtaa atacgctgtt attacaagaa cctgggcaaa
      601 taacgtacgt ctaagtgcaa ttactttcag tgatgatttt attaattggt cagaacctaa
      661 agaaatcctt aggggagatg gatttgaaga tcaaatttat tctatgccag taatttcata
      721 cgcggatatc tatttaggtt ttgcttcaat gtaccacgaa ggcgacactt taaatgaaaa
      781 ctatgataaa gtagacttag aattgaaatt ctctgctaat ttggaacaat gggatagtgt
      841 atgtaagggc gactatctca ttgaaagggg aggtggagta tacccgcaga atgctgattt
      901 tgatgctagt tgtattttca cggctgctcc aataattgaa gatgataaga tttggttcta
      961 ctatatgggt ggaaatggta atcacattgg cttccgagaa agttcattag ctagaggata
     1021 tattaagaaa gaccaatttg cttattatac taataagaga gaaggaattc cagctaaaat
     1081 atctacagtt agcttccaaa cttacgatga tgaaatttat atcttagctg atattcctga
     1141 aaatggttat attaaagttg cggtaggtac taaatacggt aatgcttatt cagattttgg
     1201 tcaggaagat atctctcttg ttcaagtttc cgatggtaag tataagttgg aatttaataa
     1261 aaaatctatc ttagatttag gtaattctcc agttgcgttc aaatttgaaa tcgagaatgc
     1321 aaaattgtat ggtattgaag gtagtattca gcaacactat ctcaaatatt aaccagaata
     1381 attcgttaac aaataatctc tatattagtg gagatagata tataaaatgg aggtcttatt
     1441 atggtaaagc ttaataaggt attaaaaggg agtgttgcat tcctgagtgc aagtttattg
     1501 ctagcagctt gtggcaataa cgctaattca aagcccgctg aaaaaacagc tgatggtaaa
     1561 acgaaaattt cgtttctatc tacatggcaa attaatgatg ttcgtccgcc taaagatgaa
     1621 acacttgttg gtcaatggtt agaagaacag ctaggtattg atattgatct tgtaactatt
     1681 cctggcgagg gagtaagttc taaagtaaat tctcttatta ctagtaacca gttaccgact
     1741 gttttgttga caacaggaga taagagtgat atcgctggta tcaacaaact tggtaaacag
     1801 ggtgcattct tagatttgtc acaacacatg gacaaactac caaactataa gaagtacctt
     1861 gaaaaaaata atgcattagc tcaaatagaa gatgatgaaa aacatattta tgctttcaca
     1921 aaattcttta ctgatgagaa tatcatgtat actacaccaa ttctgagaaa agacttactt
     1981 gttggttcag aatttgaaga tctttcaaaa attaaaactg ttgatgacta tacaaaagtt
     2041 ttgaaatatt tgactgaaaa acaaggttct ccagcattta ttcaacgtaa tggctatgaa
     2101 ggcttcatga agcgagttac accattgtgg aatttaagcc atcgtacata ctatgactat
     2161 gaatcagatt catataaaca tccagttgaa caacctcaat tgaaacaatt cgttgaatgg
     2221 ttgaaagaat tacgtaaaga taacgtactt caccctgact gggcagttat gaaagatgaa
     2281 acttgggaag gtctattggc ttctaacaag ggttcattca ctgttgaccg tatgaatatc
     2341 attggagata ataactttga taaatcattt gattggcagc cacttgttta tccagaaatt
     2401 aatggaaaac gttatttgca accgaaaaca ccgtacattt ctgattcagg ttgggtaatc
     2461 aatgccaatg caccaaaaga agaaattgat aaagcgttag aattctttaa tttcttatac
     2521 gctgatgaaa atcaagaaaa acttgctatt ggatttgaag gtaaaacatt tacacgtgaa
     2581 aaccctaata ctcaagcagg tattaaatgg ttgattcaaa tttacggtga aaatgctgga
     2641 aatgataaag cagaactgct gtttaaacat ggtaaccaag catttactcg cgttcaaact
     2701 aaattagata ttgaggcaca gccaggaaca ttccctaaag ttatgtatga tcaagtagat
     2761 aaaattaaga aagatttagg tggttttaga ccagatactc cggttctttc ctttacaact
     2821 gaagaattag atgttttaac taaatctgaa gcaggattaa atactttctt tgatgaaaat
     2881 attattaaat tcattgaagg acaaagagat atgagtgagt gggattcatt tatcaatgaa
     2941 gctaaatcta aagacttgga taaagttaca aaagtatata atgatgccta caaacgtgtc
     3001 aaagatagaa tgaaatagac taaatggtag ctctctggtt tttcagagag ctactactgc
     3061 ctgaggggga gtaagctttg tatgatgtag taattatagg tgcaggaagt tcgggcgcat
     3121 tggctgcaat tgcttcgggg cgtctagggt taaaaacttg tctaatagag aagggaagta
     3181 gaattggtgg agttcctatt aatacactaa tggggtcatt tgctaatcta tattttgatg
     3241 attctggtag agtaaatgca agtaaaattg ttggggaatt aatagaacgt attatcaaaa
     3301 aaggtggtac tgtctttaac tctatggaag aattgatgaa tgtaaatgat ttttatcaga
     3361 ttacaattcc ctatcaacca gaagtttatg aatcggtttt aactgatatg ttgattgagt
     3421 ctaaagttga tattttacta aatgttgaag ttaataatat tatttatgat agtaaaaata
     3481 ttaaaagtct tgaaatttta agtaatcagg aagttaaatt gattgattct aaagttttta
     3541 ttgatgctac agggaatgca acaattgctt ctgctagtgg agctgatgtt tatgaaaaaa
     3601 attcttctta cggttgttta atgagagttg gaggagttga tatctcaaag actatagaac
     3661 atattgaaaa aacaaagcag tggaactata tagaaggata taatcagtgg ttagaagaag
     3721 tattagcaaa tcgaaagtac agagccactg gagcagtttt aaaagatcca gtttcttatg
     3781 atcatgcccc tatgctttca aaagacgacc attttatgaa tgatgaaaaa tggaattaca
     3841 ttaaagaaag atgggaaaaa tttagattta tttacacttt agaagtatca ctatttagga
     3901 atgaattaaa aaaagctgta gaatctgggg attttaattt tgaaatttat catgatgata
     3961 aatctggagt cactatgaat ggcgacggta taagctatgg ttcatggggt caaaatgtag
     4021 cattaattaa tgttgcaaaa gcatttggat tcaatcccaa atatatggaa gatgaatcac
     4081 atgctaat
//
LOCUS       DAVLDI010000096         3961 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLDI010000096 DAVLDI010000000
VERSION     DAVLDI010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.097"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(179..3076)
                     /gene="nanA"
                     /locus_tag="VXD01_002159"
     CDS             complement(179..3076)
                     /gene="nanA"
                     /locus_tag="VXD01_002159"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV0602474.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALSPEEVQTRSQLFERGDLEKKLPEGAKISEKEDVFEGGMNNKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            complement(3364..3591)
                     /locus_tag="VXD01_002160"
     CDS             complement(3364..3591)
                     /locus_tag="VXD01_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602475.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
BASE COUNT         1079 a          882 c          647 g         1353 t
ORIGIN      
        1 tagagttgtt cacatcttat ttcaatctac tatattttat agaacagact actctgaaag
       61 tagtttcaga cctcttatga tttcgtatca gcctgaatgt catcaaaaaa agatagcagg
      121 cttaaaaacc tgctatctcc ttctattttt acaaaatcaa atgtttagaa ttcttctctt
      181 attgttctct ctttttccct agcgtaaaca gaccaaggaa gaaagctgtt agtcctagtg
      241 aagctaggag gtcactctcc ttgtttcctg tttcaggaag tgcctgctga gcaagaggag
      301 ctttgtaagt ataatcttct tttgtagtaa gagttacaag cgaatcagat cccttatact
      361 ctgcgatttc atgaacagct ggctctgtac cattaactcc ccctgtaaat tctggaactt
      421 catgcaccgc tgctttgcta ccatttactc cgccaggaac tctggcacct gctagattta
      481 caggaagatt atgcatactt tcgatgcttc ctttagctat accaataatt tcctgtccga
      541 tatcttcctt atctactgca aacaacaagg tcttgctatc atactgggtt aggaaagtcg
      601 ctgttttacc atttgccaat tgaagtgttg gagccttgtt gaccaatact tctgagtcga
      661 actccaagcc aataactcct ttgcccatct ctcctttgcc catctctcta gttcgcttca
      721 ctttcgcttc ggtaggagaa atcagatttt tgctcaaaaa ttcccaatta aattttctaa
      781 atgatagggt ataggcattt tgtccttttt cagtatgttc atacaagatg ccatactccc
      841 catttcctaa ttcttggagc gaattatagg caaactctcc tttttgaatt ggattgtgtt
      901 tgagccaagt caactcacca ttttcttcga cacgtgccaa gtggaccatc ccattttcac
      961 gtttcggtcc acctgcatta ctgaggatga tgtattcttt tccttcgtgc atcgtatgga
     1021 tagcagacat ttgaacatag acatctttaa cctgtggata acgtttgata tccttctccc
     1081 aagtcactcc tccgtcttta cttgtagcaa cctgaagatc tccagtcaaa ccacgcataa
     1141 agagtttaac atctccattg tttagttgta ccaccgttga ttctgtattt tgcgcacgtt
     1201 tattgttcat cgtagaagag tggatctttt gaccgtctac ctgacggtta tcgttgaccg
     1261 cttctccagc atgccaagtt tttccatgat catctgaata gatgacacga gaagattgcg
     1321 agccatttaa gtgagataca ttattagtcg tataaaccgg tatcaaaatc cgtcccttgt
     1381 gaggcccatt ccgaagtaca attcctgttc caggacctac acccaagaat ttcatccaat
     1441 cggctttgac catcggagta atatcttgag gcgctgacca tgtcttcccg tcgtcatcac
     1501 tgtaggacat ccatagatag ctatccttgg caattctaaa tggagaagtt ttgtttgttg
     1561 tgaagtagat atttcctagt aattggtcac ccttgtatag atcacccttg tcgctatagg
     1621 ctggtttaac aggatctaca acaacgcgat agtctgtcgc cttaccatct ggtgtataga
     1681 cagtaccatt ttctcgaatg gtataagctt ccttttctcc ctcacgatag aggatttgat
     1741 aggtttttcc atcgatttct ttgtaggctt cttctttttg tgaagacatt ccaaagattc
     1801 ccttcccttc tgggaacatg tcatagatag aaaagattcg tttggtttca ggatcttgaa
     1861 ccaacaccat atcgatattc actggtgaac cgatcgatgg gtcagaagct tttggattgt
     1921 cacgtaagtt ggtaatggtt actcggtcac cccaagtttt accattatct tcactacgtc
     1981 tgatgaccat accgatatca ccccagtcac tcgaatggag acggcgttca tctgcacctg
     2041 cgatcaaagt tcctttatct gtcttgagaa gtgctggaat acgataactc ttgattccat
     2101 ctttatttgg tttgttgttc attccccctt caaagacgtc ttctttctct gagattttcg
     2161 caccttctgg aagtttcttc tccaaatcac ctctttcaaa tagttggctt ctcgtctgaa
     2221 cttcttctgg gcttaaggca cgattataca cagtgagatt ccgaatctgt agatttgacc
     2281 cccaaaccgt attgttggca cgcttggttg ctccgatttg cacatgcgtt acatctggca
     2341 tatctttaat gaaattgcca gatttcagac ttgttcgaga taaaacacca ttaacataca
     2401 ggcgaactcg accatttggc aattctgctg ttggtttttc aactgtgaaa gtcacagaat
     2461 tccactgacc tggtttaact tttaagggtg catcgttgta attattgtaa aactgtttcc
     2521 catccgaacc acgcccctct agagtagcag tattattgta aactgccata gtgaagtact
     2581 catctttttt agtagcactt gacacagaaa agagattata gaatgctgga gccttggcat
     2641 ctggcttaaa ctccatgtga actgttgcgt tttcaagttt ctttagttta tctagttcac
     2701 ttgataaatc aactctctga ccatttgaag cattggtttc aacatcttct ttttctatca
     2761 ctgtttcgac attttccaaa tctcgtgcat agtaatctct tggaattttt tcttcttgct
     2821 tatctttcct ttcttgttct tgcttattgc cagaaagttc agtctctgaa gaaggctggc
     2881 tcttttctgt atcagttagg gttgagctct cccccgaaag ttgagtttca tttgccagag
     2941 gttgctcact tgccccttct tgagctaaaa caggagacgt tccaaatacc actgctccta
     3001 caatcataga aaccgctcct accgatagtt tcctaatgct ataacgacac ttacgttctt
     3061 gaacactccg attcatactg atcctctcta tatctatatc ccgatttctg aaataagaca
     3121 tttactccag aaaatgcact tagtttgtct tttattaact ttcttttact acagttcatt
     3181 taaatgacaa aaatgaacta aacaaactat ctcaaattgg tgccaatttt cccctctcct
     3241 ttctccaatc agactcctgc caatctagtt tatctaccaa gacaccgctg caattaaact
     3301 aaaatatctc tttataagca aatgatggac atcagcttat gctatttaca ccatacttcc
     3361 tgctcaatcc ttatcgaaca ctttttcaaa tagcttttca taagcataaa tacttgtaga
     3421 aataatggga aatataatca agctcacaat cagaatctta tccagcttaa aggggacaat
     3481 cccaaataag tgaagaaata aatcaatcag aaaactgtcg aaaaaaactg tcaaaagtag
     3541 ttcaacttgt ctttttctct gcttttttgt cttgaatgcc ttaaatatca tattattccc
     3601 cttttctaag cttcaatccc ttctctctat ctgttatttc gcatagctac tactattttt
     3661 acagcaatct atctttaaat atacataaag atagattcta tcacttttta taagtgttag
     3721 taaatttatt ataccttatt tttaaaacgc tttcaatata gtgtaatata gtagatttta
     3781 gtttcaaaaa aatcttttat ataataatgt ccttgaaagt agtttcagct gaacatttat
     3841 agtccataaa aagaaaacag aaactcatct gtttttatac tcaataaaaa tcaaagagca
     3901 aactaagaag ctagccgcat gatgctcaaa acactgtttt gaggttgtag ataagactga
     3961 c
//
LOCUS       DAVLDI010000097         3778 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLDI010000097 DAVLDI010000000
VERSION     DAVLDI010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3778
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.098"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            93..311
                     /gene="nrdH"
                     /locus_tag="VXD01_002161"
     CDS             93..311
                     /gene="nrdH"
                     /locus_tag="VXD01_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV0602476.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            392..2551
                     /gene="nrdE"
                     /locus_tag="VXD01_002162"
     CDS             392..2551
                     /gene="nrdE"
                     /locus_tag="VXD01_002162"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV0602477.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGECYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            2739..3701
                     /gene="nrdF"
                     /locus_tag="VXD01_002163"
     CDS             2739..3701
                     /gene="nrdF"
                     /locus_tag="VXD01_002163"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV0602478.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
BASE COUNT         1175 a          815 c          704 g         1084 t
ORIGIN      
        1 aaagaacacc actatattta gttcaaatca ttgacaaaat tttattttct gatatactaa
       61 gatagtatta aattttgaag aggagttaca caatggtaac cgtttattct aaaaacaatt
      121 gtgtccaatg taaaatgacc aagcgtttct tggacagtaa taatgtctct tatcgtgaaa
      181 tcaatcttga tgagcaacct gagtacgtcg atcaagttaa agagctcggt tttagcgcag
      241 ctcctgttat ccaaacacca actgaagtct tttcaggttt ccaaccagga aaactgaaac
      301 aattagcata atcttagtac atcatccaga agaaactact tttagggcta acttagaagc
      361 ctttcttttg taattagata agggaaattt tatgggatta aaacatcttg aagacgtgac
      421 ttacttccgt cttaataacg aaattaaccg tcctgttaat ggacaaatca tgcttcataa
      481 agataaggaa gccttggatg ctttctttaa agaaaatgta gttccaaaca ctatggtttt
      541 tgattcaatc aaagacaaaa tcaattacct cattgaacac aactacatcg aaacagcctt
      601 tatcaagaaa taccgtccag agttcttgga agaattggct caatttatca aagaccaaaa
      661 cttccaattc aagtcattca tggcagctta taaattttac aatcaatatg ccttaaagac
      721 taatgacggt gaatgctatc ttgaaaatat ggaagaccgt gtcttcttca acgcccttta
      781 tttcgctgat gggaatgaag ctgttgcaat cgatattgcc aatgaaatca tccaccaacg
      841 ctaccaacct gctactcctt ccttcttgaa tgctggacgt gctcgtcgtg gggagttggt
      901 atcttgtttc ctaatccaag tgacggatga tatgaactct atcgggcgtt ctatcaactc
      961 agctcttcaa ctttcacgta ttggtggtgg tgtgggaatt accctcagca accttcgtga
     1021 agctggtgca cctatcaaag gctatgaagg agctgcttca ggtgtcgttc ctgttatgaa
     1081 gctttttgaa gacagcttct cttactccaa ccaattgggg caacgtcaag gtgctggtgt
     1141 tgtctacctc aacgtctttc acccagatat catcgctttc ctttcaacta agaaagaaaa
     1201 cgctgatgaa aaagtacgtg tcaagactct atcacttggt gttgtagtac ctgataaatt
     1261 ctacgaattg gctcgtaaaa atgaagaaat gtacctcttc agcccttact ctgtagaaaa
     1321 agaatacggt gtgccattca attacatcga cattactgaa aaatacgatg aattggtcgc
     1381 aaatccaaat attcgcaaga caaaaatcaa ggcgcgggat ttggaaactg aaatctctaa
     1441 attgcaacaa gagtctggct atccttatgt agtcaacatc gatacggcta accgtgcaaa
     1501 tcctgttgat ggaaagatta tcatgagtaa cttgtgttct gagattcttc aagttcaaga
     1561 accaagcttg atcaacgatg ctcaagaatt ccttcaaatg ggaacagatg tttcatgtaa
     1621 cctgggttca accaacgtgg ttaacatgat gacttcacct gattttggtc gttctatccg
     1681 tgctatggtt cgtgccctta ctttcgttac agatagttca catatcgtag ctgtaccaac
     1741 gattgaccat ggaaatagcc aagcccacac ctttggtctc ggtgccatgg gactgcacag
     1801 ctaccttgcc caacaactca ttgaatatgg ttcacctgag tctgttgaat ttacaagcat
     1861 ctactttatg cttatgaact actggacctt ggtagagtca aacaatattg cacgtgaacg
     1921 tggtattacc ttccacaact ttgaaaaatc agactatgct aacggaagtt actttgacaa
     1981 gtatgtaact ggtgaatttg ttccaacatc agaccgtgtt aaagaactct tcaaaaatgt
     2041 ctttatccct ggtgttgctg attgggctga acttcgcgac aaggttcaag aagatggtct
     2101 ttaccaccaa aatcgccttg ctgtagcgcc aaatggttct atcagctata tcaacgacgt
     2161 ttctgcttct atccacccga ttacgcaacg tatcgaagaa cgccaagaga agaaaattgg
     2221 taaaatctac taccctgctg ctggcttgtc tacagaaacc attccttact acacttctgc
     2281 ctacgatatg gatatgcgta aagtcatcga tgtttacgct gctgcgactg aacacgtgga
     2341 tcaaggactt tcactcaccc tcttcatgcg cagtgacatt ccaaaaggcc tttacgaatg
     2401 gaagagggaa aataaacaaa cgacacgtga cttgtccatc cttcgtaact atgcctttaa
     2461 caagggaatc aagtctatct actacgtccg tacctttaca gatgacggtg gagaagtcgg
     2521 cgccaaccaa tgtgaaagct gtgtgattta gtttctagca tagaaacact atttttccct
     2581 aagcagcact gataaaatca aatctactat gtcataacat aatttatgta acattttaaa
     2641 agtcgggctt ccgacttttt gtgcgatact cctatagaat tatggtaaag tagaaataat
     2701 tgtgagttcg caatactaaa cacagaaaga gattttaaat ggaaacttac tacaaagcca
     2761 ttaactggaa tgccatcgaa gatgtcatcg acaaatcaac ttgggaaaaa ctgacggagc
     2821 aattttggct cgatacacgt attcccttat caaacgactt ggatgactgg agaaagctat
     2881 ctaacaaaga gaaagacttg gtcggaaaag tttttggtgg tttaaccctt cttgacacta
     2941 tgcaatctga aactggggtt caagcccttc gcgcagacat ccgtacacca catgaggaag
     3001 ctgttttcaa taacatccaa tttatggaat ctgtccacgc taaatcttac tcatcaatct
     3061 tttctacctt gaatactaag gctgagattg aagaaatttt cgaatggacc aataccaatc
     3121 cttacctaca aaagaaggct gagattgtca acgaaatcta cctaaacggc agcccacttg
     3181 aaaagaaagt tgccagcgtc ttcctcgaaa ccttcctctt ctactctggt ttcttcactc
     3241 ccctctacta tctcggtaac aacaaactag ccaacgttgc agaaatcatt aaattgatta
     3301 ttcgtgacga gtctgttcac ggaacctaca ttggttacaa attccaactt ggtttcaatg
     3361 aattgcctga agaagagcaa gaaaaactca aagaatggat gtacgaccta ctctatactc
     3421 tttatgaaaa tgaagaaggc tacacagaga gtctttatga cggtgttggt tggactgaag
     3481 aggttaaaac cttccttcgc tacaatgcca ataaagctct catgaacatg ggacaagatc
     3541 cacttttccc agattcagct gaagatgtca acccaatcgt tatgaacggt atttcaacag
     3601 gaacttccaa ccatgacttc ttctctcaag tcggaaatgg ttaccttctt ggcgaagttg
     3661 aagccatgca agatgatgac tacaactacg gtttggacta atactcttcg aaaatcaaat
     3721 tcaaaccacg tcagcttcgc cttgccgtac tcaagtacag cctgcggcta gcttccta
//
LOCUS       DAVLDI010000098         3724 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLDI010000098 DAVLDI010000000
VERSION     DAVLDI010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3724
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.099"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(122..655)
                     /locus_tag="VXD01_002164"
     CDS             complement(122..655)
                     /locus_tag="VXD01_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV0602479.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(744..1520)
                     /gene="recX"
                     /locus_tag="VXD01_002165"
     CDS             complement(744..1520)
                     /gene="recX"
                     /locus_tag="VXD01_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV0602480.1"
                     /translation="MKITKLEKKKRLYLMELDNVDKCYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYTIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASVLREYL"
     gene            complement(1530..2306)
                     /locus_tag="VXD01_002166"
     CDS             complement(1530..2306)
                     /locus_tag="VXD01_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEV0602481.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQEAKITSWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     KLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2363..3718
                     /gene="rlmD"
                     /locus_tag="VXD01_002167"
     CDS             2363..3718
                     /gene="rlmD"
                     /locus_tag="VXD01_002167"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV0602482.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1165 a          667 c          697 g         1195 t
ORIGIN      
        1 ttctttctag taatgtgttg taactctgct ataatggatt tattcctttt tgtgtttaca
       61 caatttattt tatactacca aaaaaacaag gtcaggattt tgttcctgac ctttgacaac
      121 tttaccgatt ctttagttct acatagcgct tgtaccaaat gtttacatag gcttctgaga
      181 aaggaccacg tccattgtta atccaatcaa caagaatttt gacatgttct tttaaaatat
      241 agtccaagtc atcagaataa ttcattttgc gtttgtgacg ctcgtattct tcaacgtcca
      301 agagacgttt ttccccatct gtaaaaattt taacatccaa atcgtaatca atatacttca
      361 gtgcttcttc atccagatag taggggctag ccatattgca atagtaagaa gttccattat
      421 cacgaatcat ggcaatgata ttaaaccaat atttcttgtg aaagtaaaca atagccggtt
      481 ctcgagtgac ccaacgacga ccatcacttt cggtaacaag tgtatgatcg ttgacaccaa
      541 taatggcgtt ttctgttgtt tttagtacca tggtgtcccg ccaagttcgg tggagactcc
      601 catcatgctt ataactttga attgtaataa agtcgccttc ttttggaagc ttcataacta
      661 accaactttc tacaatttat aagtttatca tttactattg taccataaaa ttacctaaaa
      721 tctgtgaatt tcacttggaa atattaaaga tattctctaa gaacgcttgc tatatccgaa
      781 aaatcgtagc cctttcgtgc taaaacttga gttaaacgct gcttcagttc gtatccttca
      841 tactttcggg catacttagt atattgctta tcaagttcct tgaagatgag ttcctgagtc
      901 gtttcttggt caacttggct atctaagtcg tcaaaggcaa ttttagcatc agaataagag
      961 aagcccttgt tagtcaagtt ctggataatc ttatcttgca gggcacgagc tggaagtttt
     1021 ccctcatatt ttttcaatag tttattagct acacgttgag caacttcaga aaaatcaaat
     1081 tctttcaagt tctcttctat agtagatttt gaaatccctt tttgagctag tttctgagtc
     1141 agcacataag gacccttgtc tcctgaaagt tgattggtat tgatgatagt ataagcgtac
     1201 tgaccatcat taatccactt atcttcttta agattagcaa taacttgaga aacgatgttt
     1261 tcatcaatat cgtatttttt cagatattct ctgacttctt tttcagtgcg tgctttaaag
     1321 gataagtggt agagggccag attcttacca taagaaaact gggcaaaatc ctgaatctcg
     1381 gtcagttcct ctttactaat gaccttatct ctcgataaca taaaacgaac aattgtgtct
     1441 tcggtgatat agcatttgtc gacattatca agctccatca gatagagtct ttttttcttt
     1501 tcaagttttg tgattttcat aatttccttt catctaaatg cttcgaaagc tgcaacaagt
     1561 cggagtttat ccatatttac atattctcta ccgtaatagt cgagaaataa ttcagcatac
     1621 gtagcatctt gtaggttgta atgaagggac caaattgccc aaaagaggtc gatatgtcgg
     1681 tcactaaaac cagccaatcc caagtcaata aagcaagaaa aatgagaggc atccttcaag
     1741 atgaaatttg gcaggcaggc atctccatga ataaaagcat cagctttgag aatgtaacct
     1801 ttctcttgta tcagttggta agcttcttca cgactgtgaa tgtgaaattg aggcagaaga
     1861 gtcttgttat aaaaagtccc cttctgatag ttttttaagg ctttttcttt ataacgcttc
     1921 agatgatttt ccgacggaaa agattgtggt ttaagactgt gaagtttgtt taatgcttga
     1981 gccagggttt gacagagttt ttcgggttga tttaaaaaag cgagagcgtt gctgccaatg
     2041 gcttctttag tcagaaggaa gtccttattt gctgataaat aggtaatcac tggagttccc
     2101 aatccttcag tttcgaacca acttgtaatc ttagcttctt gagctaatct gcctttttga
     2161 tctattttta aatagtaacc tgaatctata tataggacag ttgcacttga atgagaagaa
     2221 ctatcagaga gattagctcc cttgatatag cttcgtaatt gttcagggaa atctagtata
     2281 ctaaagcgag gtgtttttga attcatgctt ttattgtaac atattcttaa atatcttaga
     2341 aactccatgg tataatagac atatgaatct gaaagtgaaa caaaaaatac cattaaaaat
     2401 caagcgcatg ggaattaacg gtgagggaat cggcttttac caaaaaacat tagtctttgt
     2461 accaggagct ctcaaaggcg aagatatcta ttgtcagatt acttctatta gacgcaactt
     2521 tgttgaagca aaattactga aggtcaacaa gaagtctaaa tttcgaattg tgccatcttg
     2581 tactatttat aatgaatgcg gaggctgcca aatcatgcac ctgcattatg ataagcagct
     2641 ggagttcaag acggacttac ttcatcaagc gctgaaaaaa tttgctcctg caggatatga
     2701 aaattatgaa attcgtccaa ctattggaat gcaggaacca aaatattaca gagctaagtt
     2761 acaatttcag actcgaaaat ttaaaaatca ggtcaaggcg ggcttatatg cacaaaactc
     2821 tcactattta gtagagttga aagactgcct ggtacaagat aaggaaaccc aagtgattgc
     2881 taatcgctta gcagaattac ttacttatca ccagattcca atcacggatg agagaaaagt
     2941 tctaggtgtc cgtactatta tggtccgacg cgcgagaaag accggacagg ttcagattat
     3001 tattgttaca aaccgccagc ttaatttaac tcaattggta aaagagttgg ttaaagattt
     3061 cccagaagtt gtgacagtag ctgttaatac aaatacagct aaaaccagtg agatatatgg
     3121 tgaaaagaca gagattatct gggggcaaga gagtattcaa gaaggtgtac tcaattatga
     3181 attttcacta tcccctcgag ctttttatca actaaatcct gagcaaacag aagtcctcta
     3241 tagcgaagca gtaaaagcgc tggatgttga taaagaagac catttgattg acgcttattg
     3301 tggagttgga acgattggat ttgcctttgc aaagaaagta aaaacactca gaggtatgga
     3361 tattattcca gaagctattg aagatgccaa gcgaaatgct aaaagaatgg gatttgacaa
     3421 tactcattat gaagctggaa cggcagaaga gattattcct cgttggtaca aggaaggcta
     3481 ccgagcagat gctttgattg ttgacccacc acgtacaggt ctggatgata agttattaga
     3541 tactattctt acttatgtac cagaaaaaat ggtttatatt tcttgtaatg tttcgacctt
     3601 ggctcgtgat ttggtacgct tagtagaagt ctatgatctt cattatatcc agtcggtcga
     3661 tatgttccca catacagctc gaactgaagc tgttgtaaaa ttaataaaaa aagtttaaaa
     3721 aagg
//
LOCUS       DAVLDI010000099         3461 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLDI010000099 DAVLDI010000000
VERSION     DAVLDI010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.100"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..133)
                     /locus_tag="VXD01_002168"
     CDS             complement(<1..133)
                     /locus_tag="VXD01_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV0602483.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     "
     gene            complement(310..921)
                     /gene="rpsD"
                     /locus_tag="VXD01_002169"
     CDS             complement(310..921)
                     /gene="rpsD"
                     /locus_tag="VXD01_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV0602484.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1116..2168)
                     /locus_tag="VXD01_002170"
     CDS             complement(1116..2168)
                     /locus_tag="VXD01_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV0602485.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2165..2863)
                     /locus_tag="VXD01_002171"
     CDS             complement(2165..2863)
                     /locus_tag="VXD01_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV0602486.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(3030..>3461)
                     /locus_tag="VXD01_002172"
     CDS             complement(3030..>3461)
                     /locus_tag="VXD01_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEV0602487.1"
                     /translation="GTQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTAN
                     GSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSE
                     DKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT          964 a          768 c          661 g         1068 t
ORIGIN      
        1 ttttctcttt tagctttaac cagccataaa tggtattacg tgagatttgg aaaacgtgtg
       61 atgcttctgt tatactacct gttcgctcac aataagagag aactttttta cgaaaatcta
      121 ttgaatatgc cataaaagat tataccacat tgtgtactat ttttggttca ttttactata
      181 tcactttgga ctatatcggt ctagttatgt ctaaacgatt atagctggat actaagagaa
      241 atcaaaaaag cactaaggga gaacgtccca aagtgcttaa tatcaaagcc tatcttattc
      301 aataaaatat tacaacattt tgttgtagaa ttcaacgaca agtgcttcgt tgatttctgg
      361 gttgatttcg tcgcgttctg gcaagcgagt caatgaacct tccaattttt cagcgtcgaa
      421 tgatacgaat gctggacgtc caagagtagc ttctactgct tcaaggattg ctggaacttt
      481 caatgatttt tcacgaactg agatcacttg acctggagtt acgcggtatg atgggatatc
      541 aacgcgtttc ccgtcaacaa ggatgtgacc gtggtttacg aattgacgag cttgacgacg
      601 agtagtcgcg agaccaagac ggtaaacaac gttatccaaa cgacgttcca aaagaagcat
      661 aaagttgaaa cctaggattc cgcctttgat ttttgtagct tgtacgaaca agttacggaa
      721 ttgtttttca cctacaccgt aagtgaaacg aagtttttgt ttttcagcca attgcaaacc
      781 gtattctgac aatttagaac ggttgtttgg tccgtgttgt cctggtacgt agttacgacg
      841 tgccaattct ttacctgtac ctgtaagtga aaggccaagg cgacgagctt gtttccaaga
      901 tggtcctgta taacgtgaca tatgaatgtc ctcctgatat aaataatatt tcggtggaaa
      961 tagtcactta gaaagccctg attcgtgcag atgcccttcg cctaaacagc caaggttact
     1021 tgtcataaga cacctgttga cgagcttcat gctttcctgc tgatatttca cacaaaatct
     1081 attctaccat gaatagctgg atttgtaaag gggttttagg ctttattttc actaccagag
     1141 aggttgagaa cgagggtaaa ggtacttcct agaccgtact ggctgctgac tgtgatttcc
     1201 ccacccaatt gatgggccaa ttcacgcgca atcgcaagtc ctaatccatg accacctgtc
     1261 ttcatgttac gcgaagtttc gacacgataa agacgtttga aaatattttc caaatcctct
     1321 ggggcaatac cctgcccttc atcggtcaca ctgattgaaa gctggtcctt ctccagctta
     1381 gccaccactt ccagcttggt tcctggagca gaatatttaa aagcgttatc gaccagattc
     1441 accaagatac gagaaagctt agcataatct ccctcaatcc gggcagactc tgggattacc
     1501 tgcaagtgga catctcttct ctcctgctca atcaaaaact gaaattcact catgcactca
     1561 attaagagct tgtccagaaa aatactgtct ttactggtag tttccacctg atttctagct
     1621 gtgtttaggg tcaaaaaatt caactcctca accagtttat tgagcctctc cgtctggcgt
     1681 ccaatggttg ctagataatg agcttgctcc gactccttga taatcccatc caaaatccct
     1741 tctaccgtcg cttgaatcga agtgataggg gtcttaatat catgcgacaa ctgggcaatc
     1801 atcaagccct tttctcgttc gctttcttcc aaggaatcaa agcttacctg caaatcatgg
     1861 gacatctcat taaaagtttg ccctaattgc tgaaattcta caggaccttg aacctccaaa
     1921 tttgaaggaa aatccttggc cgctacccgc ttggcatgct ccttgagttt gcccaacgac
     1981 gtaaagactg gcaataggag aaagagacta atcccagcac cgacaaggct ggcaacgatg
     2041 gtcatcccaa gcaaaaagta aatctcgcct ttcgcaatca gcattttttg aacagcccaa
     2101 aaaacaacca aaatggttaa gagggttgaa ataatatatc caaccaaaat ataacttttt
     2161 agtttcatgt ttgtcctctc ggtttctcta tcttatatcc caacccccaa actgtcttaa
     2221 tagtgggcgt ttggtcacta ctatattttg ccagctcctg tcgaagagca tggatatgca
     2281 cattcaaggt attggtgtca tccacgtagt cttctttcca gatcttttca tagaggtctg
     2341 tcttggagaa aactcgctct ggattgctag ctaaaatcca cagcaattca aatgatttaa
     2401 cagttaaatc cagcatttct tctcctattt gaacttcatg actactatga ttcattttta
     2461 gattgccaag ggaaatcagc tctgtttcgc ccccacgatg aaggcggcgc aaaatattgt
     2521 ggacacgcaa aaccagctca cgtgggctaa aaggcttagc aataaaatca tctgctccca
     2581 agctcaggcc gtaaatcttg tcctgttcac tggtcttagc agtaataaat aggaaaggct
     2641 gctctggtga taagtattga acctcactga ttaaatcata accatccatc cgaggcatca
     2701 tgacatctgt gataatcaaa tcaatcggtt ttttcttgaa cagctctagc gcttccagtc
     2761 catcatgggc taccaagacc tgataacctg cctgaattaa gtatctctga tgaatatctg
     2821 tgatttctac ctcgtcgtca acgagtaaaa ttgtctttcc catctgtctc tcctttgata
     2881 aaaacagtgc tatactgctt taagtataac actattttta ttgttttacg atgattttaa
     2941 tctgctattg aaagaaagtc ctgattgctg attgagttgt taaactaatc ttagtcagcc
     3001 cactatccat catttatttc cttagctgat tagttttctt cttttttgtt tttcaaacct
     3061 agaccaccga gtaaacctgc aagcgcaagc ccaaggaaac caatacttgc cattgatgtt
     3121 tgagtctcac cagtatttgg tagcatagct ttatcctctg acatcatcgt atcagacatc
     3181 ttgttagcag aagcagccat gttttcacct gccatcgtgt tggtagaact tgtcatggtg
     3241 tcagcaggca tgctatctgt agtacctgta gcatgattgt gattcatcgg agtcacgcca
     3301 gaaccagagt tagaaggtga taatgaacca tttgctgtgt ctgatgtttc tttaacattt
     3361 atcttaatag tgactttttt agttgctacg atgttgtcca agtctggttt accgtctttg
     3421 ttaccataga cattgactgt agcgctgtaa gtttgagtac c
//
LOCUS       DAVLDI010000100         3210 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLDI010000100 DAVLDI010000000
VERSION     DAVLDI010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3210
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.101"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..185
                     /locus_tag="VXD01_002173"
     CDS             <1..185
                     /locus_tag="VXD01_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV0602488.1"
                     /translation="EYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDTSSSG
                     VTLITGKNGTGKSTLL"
     gene            complement(551..1861)
                     /locus_tag="VXD01_002174"
     CDS             complement(551..1861)
                     /locus_tag="VXD01_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV0602489.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2098..2970
                     /locus_tag="VXD01_002175"
     CDS             2098..2970
                     /locus_tag="VXD01_002175"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV0602490.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3101..>3210
                     /locus_tag="VXD01_002176"
     CDS             3101..>3210
                     /locus_tag="VXD01_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV0602491.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYG"
BASE COUNT          993 a          538 c          722 g          957 t
ORIGIN      
        1 aagagtatga aaacagaact gtttcttttg ctattagttc aaaaggagaa aaaatgaaag
       61 tagaaaatat ttcgtatagg gtggatcatc gtatattgtt tgataatatt tcttttgata
      121 cttcgagttc aggcgtgaca ttaattactg gtaaaaatgg tacaggaaag tcaactttac
      181 tatagtagat tgaaactaga atagtacaca tctacttcta aaatattgtt agaaattgat
      241 ttgactatcc tgatctattt gtcctgttct tatttcattt cactatatct caaattgagt
      301 atgacgaagt gcgctcccat gtcctgggaa cgcactttct tcatattttt catattcttg
      361 aatccatcga taaagactat tgggatgaat ttttaaagtt gaactaatca tttttacagg
      421 atgagattta cagcagagag tttgaaggct ttatcaaagg tttttcttgg cataatgact
      481 tttcctcgtt tccacttaat tttgtgtcta ctttattata ccaagtccac ccttaagtta
      541 gataataaat ctaacttaag gaagctagaa ggatgagaat ccaggtggtc aagagtccca
      601 aacttaagct gatggggaca cccagaataa tttgcttttt gaaggcaagg ccacgttcct
      661 ctatattggg aagtgagagt tgaatgagag aaccagctga tgaaaagggt gagatattag
      721 tagatagagc gccaataacg gtggctgttg tgagtaagtg aatatcaatc tgaggatttt
      781 gagcactgat gatagcaatg atgggaaaga gggctggagc tacaacggat agggtggaac
      841 taaagagtga catcactccg gctatcacac aaaagaacag aggtaaccag aaatgaggaa
      901 tggttgttgt catgaggtgc cctatcagtg tgactaaacc tgacttgacc gctagagaca
      961 ttagtaagct catgccgcag agcatgataa ttgtagccca gggaacctta gctaaaatgg
     1021 cttcttgctt ccctaatttg agccttaagg cgaggcagac catgagtatt gagacaaagc
     1081 caatatcaaa tgttttttga taagtagcta tccaggcgat gtttgggaaa atgagatgca
     1141 acaagggaaa aagccaaacc aaaaccatgc tgctgatcat gagcaaggtg gtttgtcttt
     1201 gaaccttgct gaggagtggt ggttggtcaa tagtcaagga tgagtttgtt cttcccttac
     1261 tatagtgact gtaacaggat aataaaagca agacgatgag tgggtagata atgctgacga
     1321 taaagatatg attgccaagt gaaaaagctt gctcctccca tcccatttgc ttaaacaggc
     1381 cttgaaagac aatgcctgag ctactggtta tcaaattagc ccctcctgaa gctccccaat
     1441 tgacggcttg agctccaatc aaagggtgtt tgtccgcttt ttgacagagg gtaatcgcta
     1501 gaggacagca aacggccata gtagtgaaaa atccagcacc taaagcagac aaaagggttg
     1561 ccatcaggta taaaatcatg tagagggcgt tagggtgggt gcgtgtgcgg tagagaatgt
     1621 gttgagccaa aacatcaaga gtaccgttag ttgttgcaac gttataaaag agagagacgc
     1681 taaaaatggt aaaaaagagt gaggttggcc aaaaatgaag aagttctttg gggcttaatc
     1741 ccatgagagt ggttgcgatg aggtaagaaa aagcaatagc cagcaggcca atattgattt
     1801 tggtgcggta accaattcca atggctagag caatggcgct aatcattatt aaatgaatca
     1861 ttgaattgtc ctttcagtta gaatatggaa ataggttggc aattttggcg ctcaaaagac
     1921 cacctgtttc ctattggtac ttgactatta tacacaaaaa aaatacaatt gtcttgacaa
     1981 ttgtattgac acttgttaga attaaaaatg aggtattcag gcttgtgatt tcctatggaa
     2041 gttaatagta attgcctcta gtgcttacaa gtgatattaa aaatagagga cttagtgatg
     2101 tcaatcattt caactgattt aacccctttt caaatagatg atacattgaa agcagccttg
     2161 cgagaagatg ttcattccga agattacagt accaatgcca tttttgatca tcatggccaa
     2221 gccaaggtgt cgctttttgc caaggaagct ggtgttttag cgggactaac cgtttttcaa
     2281 agggttttta ccctatttga tgccgaggtg accttccaga atcctcatca atttaaggat
     2341 ggggatcgtt tgactagtgg cgatttggtt ttagaaatca taggctcggt gagaagtctc
     2401 ttaacatgtg aacgcgttgc cttgaatttt ttacaacatt tatcagggat tgcttcgatg
     2461 acagctgctt atgtagaagc cttaggcgat gattgcatta aggtatttga tactcgaaaa
     2521 actactccta atttacgtct ttttgagaaa tatgccgtga gagttggcgg tggctataat
     2581 catcgcttta atttatcaga tgctatcatg ctaaaagaca atcacattgc ggcagtaggt
     2641 agtgttcaaa aggcaattgc tcaagcgcgt gcctatgccc cttttgtgaa aatggtcgag
     2701 gtggaagtgg aaagccttgc tgctgccgaa gaagctgcgg cggcgggtgc tgatattatc
     2761 atgttggata atatgtcatt ggaacagatt gaacaggcca ttaccctaat tgcaggacgt
     2821 tctcggattg aatgttctgg aaatattgat atgaccacta ttagccgttt tcgtggttta
     2881 gcgattgatt acgtctccag tggtagttta acccatagtg ctaagagtct tgatttttcc
     2941 atgaagggtt taacctacct tgatgtctaa gttgtaaaat aaactaactt tttaaaggat
     3001 gtctttcctc tagaacgagt tttatgtcag atagtttaaa cgcctcttca aatatagtaa
     3061 aatgaaccaa aaatagtaca aaatgaggta taatcttctt atggcatatt caatagattt
     3121 tcgtaaaaaa gttctctctt attgtgagcg aacaggtagt ataacagaag catcacacgt
     3181 tttccaaatc tcacgtaata ccatttatgg
//
LOCUS       DAVLDI010000101         2941 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLDI010000101 DAVLDI010000000
VERSION     DAVLDI010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2941
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.102"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..154
                     /locus_tag="VXD01_002177"
     CDS             <1..154
                     /locus_tag="VXD01_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type I restriction endonuclease subunit S"
                     /protein_id="HEV0602492.1"
                     /translation="KKILLPLPPLALQNEFADFVVQVDKSQLAIQKSLEELETLKKSL
                     MQEYFG"
     gene            214..450
                     /locus_tag="VXD01_002178"
     CDS             214..450
                     /locus_tag="VXD01_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV0602493.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            447..860
                     /locus_tag="VXD01_002179"
     CDS             447..860
                     /locus_tag="VXD01_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV0602494.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSPSALNMIVNLPEQ
                     FVFGKPLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSITVEEA
                     VKMCVTIAVEALTDEKMTSYSKWISEHSVREKVKK"
     gene            978..1943
                     /locus_tag="VXD01_002180"
     CDS             978..1943
                     /locus_tag="VXD01_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0602495.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            1977..>2941
                     /locus_tag="VXD01_002181"
     CDS             1977..>2941
                     /locus_tag="VXD01_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0602496.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIMVSYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNT
                     KNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTIRGTVGNVAYYDELIKYKHLR
                     INSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITK"
BASE COUNT         1077 a          423 c          567 g          874 t
ORIGIN      
        1 aaaaaaaata cttctccccc tccccccact agccctccaa aatgagttcg cagactttgt
       61 agtccaggtc gacaaatcac aattggcaat ccaaaaatct ctggaagaac ttgaaacttt
      121 gaagaaatct ctgatgcagg agtattttgg ctgatattct gccattgtaa ttacggtaat
      181 gatttgttat aatacttcaa aggaggaaat cagatggtag taaaaacaag aaaacaagga
      241 aattcaatca ccattacgat tccaagtgaa tttaatattc caagtggtgt taaatacgaa
      301 gcgaaattgt taccaagtgg tgagattatc tttactcctg aagaattggg gcagcaggtt
      361 tcttatgtat ctgatgatgc ctttgactta aatttagata aaatatttga cgaatacgac
      421 gatgttttca aagctttggt ggaaaaatga caatctattt gacagaaaag caaattgaaa
      481 aaataaatgc tttagcaatt caacggtatt ctccaaatga gaaaattcaa acagttagtc
      541 cttctgcctt aaatatgatt gtgaacttac cagaacaatt tgtctttggg aagcctcttt
      601 atccaacaat ttttgataaa gcaacgatac tatttgtcca attgataaag aagcatgttt
      661 ttgctaatgc taataaaaga actgctttct tcgttttggt caaattttta caattaaacg
      721 gctatcgttt ttctataacg gtagaagaag cagtaaaaat gtgtgtaacc atcgcagtag
      781 aagctttaac tgatgaaaaa atgacaagct actccaaatg gatttctgaa cattctgtta
      841 gagaaaaggt caaaaagtaa cctagtatgc tggatttgaa tgagcacaag aaaataaatg
      901 aacagacaat attagaattc tgtaatgcag aaactgatat tgtctctttt tattgatgaa
      961 taagaaagtg agaaattatg gaatcaaaag ttacaattat catgcaagaa atgttacctc
     1021 ttttaaataa tgaacaatta ctagcgttga gagagagttt agaacatcat ctagtagacg
     1081 gaaaaaagca gcagaagtat tcgaataata acctgttgca actatttatt accgccaagc
     1141 aggtagaggg ctgtagctca aaaacaattc gttattacca gaggacgatt gaaaacttgt
     1201 ttaatgctat taaagagtct gtgacacaac tcacaacaga tgatttaagg agttatttag
     1261 caaattacca gtctgaaaag gattgtagta aggcaaattt agacaatatt aggcgtatat
     1321 tgtcttcttt ttttgcttgg cttgagcaag aggaatatat cattaaaaat cccattcgac
     1381 ggataaagaa aattaagact gagcaaaatg tgaaggaaac ttatactgat gaacatttgg
     1441 aaattatgcg tgataactgt gaaaatttga gagatttggc aataatagac ctactagcat
     1501 cgacaggtat gcgtgtaggg gagcttgtac agttgaatcg ttcagatatt gattttgaaa
     1561 acagagagtg tgttgtcttt ggtaaaggaa agaaggagag accagtatat tttgacgctc
     1621 gtacgaaaat tcatttaaga aactatctta acgacagaaa agatagtcac cctgctcttt
     1681 ttgtaacgtt agttggaaaa gtccagaggc ttggaattgc tggtgtagag attcgcttaa
     1741 gaaagttagg agacaaactc ggtatacaaa aggttcaccc acataagttc agaagaactt
     1801 tagcgactaa ggcaattgat aaaggtatgc ctatcgaaca agtccaaaaa ctgctaggtc
     1861 atagcaagat tgacacaacc ctggcctatg ccatggtcaa tcaaaataat gtcaagcatt
     1921 cacaccaaaa attcatctct taaaagcaaa tcccgatatt ccgaggaggt ggttgcatga
     1981 agaaagtgaa attagggcaa gtggctactt ttatcaatgg ctatgctttt aaacctcaag
     2041 attggtcatc tgaagggaaa gagattatca gaatacagaa tctgactaaa acttcaaaag
     2101 ggataaatta ttattcgggt acgattgata aaaaatacat tgttgaagct ggtgatattc
     2161 ttatttcgtg gtcgggtaca ttaggggttt ttcagtggtg tggaagatcc gcagtgttaa
     2221 atcagcacat ttttaaagtg gtttttgata agatagatat agataaatcg tattttaaat
     2281 atgttgttga aaaaggttta caagatgctg taaaacatac tcatggttcc acaatgaaac
     2341 atttaactaa aaaatatttt gataatatta tggtttcata tacaaatttg ggagagcaac
     2401 aaagaattgc aagtgagctg gatttgttaa gcaagctgat tttaaggaga caagaacaac
     2461 ttgaagagct taatctactt gtaaaatccc gatttaacga gatgtttggg gaaaataaaa
     2521 tatttgaaag cattgataac ttatttgata ttatagatgg tgataggggc aaaaattatc
     2581 ctaaatcaga tgagttgttt agtgaggagt actgtttatt tttaaataca aagaatgtta
     2641 ctaaaaacgg attttcattc gatacaaagc aatttatcac taaaacaaag gataaattac
     2701 ttcgaaaagg caaacttgag cgttatgata tagtcttgac aataagaggt actgttggaa
     2761 atgtagcgta ctacgatgaa ttaataaaat ataaacattt acgtataaat tcaggtatgg
     2821 taatattacg tcccaagaca ccaaatctaa atcagaaatt tattatccat gttttaagga
     2881 ataataatta tagtcgagtg atatcaggaa gtgctcagcc tcagttacca attacaaaat
     2941 t
//
LOCUS       DAVLDI010000102         2918 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLDI010000102 DAVLDI010000000
VERSION     DAVLDI010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2918
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.103"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..381
                     /locus_tag="VXD01_002182"
     CDS             <1..381
                     /locus_tag="VXD01_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602497.1"
                     /translation="LNNTTLVNMITELSEDEIDRIEAQEEKKYVVTFPKWILDKAEKD
                     VRARNESNNSSVVYYIDSENRLASIDIDEVEPLELISLLENPDVKKMLKEEILKKMLD
                     GYYSKLPRHIIKDIINSYQEKNIQ"
     gene            complement(936..1337)
                     /locus_tag="VXD01_002183"
     CDS             complement(936..1337)
                     /locus_tag="VXD01_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV0602498.1"
                     /translation="MLFFSISNDLLQLLTSWKEQQRYELAKFGILSNPEQFVFTYIDT
                     KGNINKPLHADYLNNKMKSIRKRHKELTHATPHKLRHTGATLAKKAGMSLEAISKALT
                     HSDTGTTQIYVNTSNVVPMTVGEFALKSLKQ"
     gene            complement(1713..2849)
                     /locus_tag="VXD01_002184"
     CDS             complement(1713..2849)
                     /locus_tag="VXD01_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001857906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV0602499.1"
                     /translation="MSGVRRAGKSVLFQLYKEELIATGVDEDQIISINFEDLSYYDLR
                     HFQTLFAYIKEQLIGEKTYYIFLDEIQHVEKFELVADSLFILPNVDLYLTGSNAYFMS
                     SQLATNLTGRYVEIEVLPLSFEEYLSGQSLTENLNTTEIFNNYLFSAFPYLLQTSSYA
                     EKIDYLRGIYNSILLNDIVTRLGNPNPTIIERIVRTLLSSTGSLISTNKIRNTLVSQN
                     VSISHNTLENYLTTLTDSLLFYSVPRFDVKGRALLQRLEKYYPVDLGLRHLLLPDHKE
                     DIGHILENMVYLELRRRYSQVYVGNLDKYEVDFVVVTDLGHYAYYQVSETTLAPETLE
                     RELRPLDAIKDQFPKYLLTMDTIQPTANYNGIEKKNIIDWLLEK"
BASE COUNT          960 a          437 c          512 g         1009 t
ORIGIN      
        1 ttaaacaata ctacactcgt aaacatgatt acagagttat cagaagatga aattgatagg
       61 atagaggccc aggaagaaaa gaagtatgtt gttacgtttc caaaatggat tttagataaa
      121 gcagaaaaag atgtgcgagc aagaaatgag tcaaataact cgagtgttgt atattatatt
      181 gattcagaaa ataggttagc tagcattgat attgatgaag ttgaaccgct tgaactcata
      241 tccctgctag agaatcctga tgtaaaaaaa atgttaaaag aagaaatttt gaagaaaatg
      301 ttagatggtt attacagtaa attaccaaga catattatta aagacataat aaatagttat
      361 caagaaaaaa atattcaatg aatttaataa taaaatttca tcatttaggg caaattactg
      421 ataaagctga ctcgttttgg ttggttttgt agaaaaattt gccctattta gatgaaaatg
      481 gttgaaatta gttgagaact agtaaatatt tggtagttaa aaatggtttg attaaaggta
      541 attgaaagaa cttagttatt aggttagcca aaccaggtct taagaaagct cgtaaagcat
      601 cacaatttag taagcgttaa ttcgaaagaa ttactatact tatacagagc acctttcggg
      661 gtgttctttt tttatacttt cttactaaat tggtgtaatt gacacagttg ttgcgacttt
      721 agtcgcttac aaatgtggct gcaacctgac aaggtcagtt gcctcaaaac gttaatcaat
      781 acgattatat caacgtttca aagcactcaa aagttcacct tatttttata gtaaaatgaa
      841 ataagaatag gacaaatcga tcaggacagt caaatcgaat tctaacaatg ttttagaagt
      901 agaggtgtac tattctagtt tcaatctact ataccttatt gttttagaga ctttaaagca
      961 aattcaccta ctgtcatagg aactacatta gaagtattta cataaatctg tgttgttcct
     1021 gtgtcactgt gtgttagagc cttagaaatg gcttctaagc tcattcctgc ttttttagca
     1081 agtgtcgctc ctgtatggcg taatttgtga ggtgtagcgt gtgtcagttc tttatgtcgc
     1141 tttctaatgc ttttcatttt attgttcaga tagtcggcat gtaaaggctt gttgatgttt
     1201 ccttttgtgt cgatatatgt aaaaacaaat tgttctggat tactgaggat gccaaacttt
     1261 gctagttcat atctttgttg ttctttccaa gaggtaagaa gttgaagtaa atcattagaa
     1321 atagagaaaa ataggatagc aaaagctcta tttcaggaga aaatgaagca aatatttcca
     1381 taataaaacg catattatca aggttgttca atacctgata ctatgcgctt ttctgatttt
     1441 aaagactgat tgctcagtct ctttttcatt ataattcagt tacaatttaa tcttatttga
     1501 gaaagtgggt gatgctattc tctaataaga ctatgatatt aatttttgat agtacttcca
     1561 gaaattatag atcccctttc atccccaatt tctattttca agtgtccgta ttatatagcg
     1621 tattcgaaat tcactatatc ttgttaggat ttgggtagaa tcattgataa cagactgttg
     1681 caaatctaat tagctgtatg atttatattt atctattttt ctagtaacca atctataatg
     1741 tttttcttct cgattccatt gtaattggct gttggctgaa tcgtatccat tgttaataga
     1801 tactttggga attgatcttt aatggcgtct agtggtctaa gttctctttc tagtgtttct
     1861 ggagcaagtg ttgtttcact gacttgataa taagcgtagt gaccaagatc agttacaaca
     1921 acaaaatcaa cctcatattt atctaaatta ccaacatata cttgtgaata tctacgtctc
     1981 aattccaaat agaccatatt ttccaagata tggccaatat cttctttgtg gtctggcaat
     2041 aagaggtgtc gtaaacctaa atcaacggga taatattttt ctaagcgttg caataatgct
     2101 ctacctttta catcaaaacg tggaacggaa taaaaaagca aactatctgt caaagtcgtc
     2161 aaataatttt ccaaagtatt atgggagatt gaaacgtttt ggctgaccag ggtattgcga
     2221 atcttatttg ttgatattaa gctacctgta ctactgagaa gggttcggac aatgcgctca
     2281 ataatagtag gatttggatt tcccaatcta gtgacaatat catttaacag tatggagtta
     2341 tatattcctc ttagataatc aattttttca gcgtaagatg atgtttgcaa taagtaaggg
     2401 aaagcactaa agagataatt gttaaaaatt tctgttgtat tcagattttc tgtgagagat
     2461 tgacctgata gatattcttc aaatgacaat ggaagaactt ctatctcaac ataccgaccg
     2521 gtcaagtttg tagctaattg gctactcata aagtaggcgt ttgatccagt caaatagagg
     2581 tcaacatttg gtagtataaa tagactatct gctaccagtt caaatttttc aacatgttga
     2641 atttcatcta aaaagatata gtatgttttc tctccaatta actgctcttt tatataagca
     2701 aataatgttt gaaaatgtcg gagatcatag taactcagat cctcaaaatt gatggatatg
     2761 atttgatcct cgtctacccc agttgctatt aactcctctt tatagagttg aaagagaaca
     2821 gatttaccag ctcgcctaac tccactcaca actttgatga tttgtcggtc acgatgtctt
     2881 cttaaaaaat ctaaataatg tggtcttttg atatagtt
//
LOCUS       DAVLDI010000103         2702 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLDI010000103 DAVLDI010000000
VERSION     DAVLDI010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2702
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.104"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            134..820
                     /locus_tag="VXD01_002185"
     CDS             134..820
                     /locus_tag="VXD01_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV0602500.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNKLLMADISTFEEGKVAVESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            821..1753
                     /locus_tag="VXD01_002186"
     CDS             821..1753
                     /locus_tag="VXD01_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV0602501.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1764..2693
                     /locus_tag="VXD01_002187"
     CDS             1764..2693
                     /locus_tag="VXD01_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV0602502.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPSAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
BASE COUNT          864 a          363 c          506 g          969 t
ORIGIN      
        1 taaaatattt ctataaatta atttaacttt cctgataggg ctgttcatat cttatttcaa
       61 ttcactatat aaataaaatt gtagtagatg ttattgaatt agtaaaaaaa ataaaaaaac
      121 ggaggttttc tgaatggaaa ctaaaaaaat taaaaattta aaaggtcaaa taattgtttc
      181 ctgccaagcg ttagaaggag agccacttta tactccaaat ggaggagtga tgccgttatt
      241 agcaaaagcc gcctttcaag caggcgctaa aggtattcgt gctaattctg tccgcgatat
      301 ttcagaaata aaagaagaag ttgacttacc aattataggt atcataaaaa gagattacga
      361 tggctttgaa ccttttattt cagcaactat gaaagagatt gatgaattag ttagtgaagg
      421 agtagacatt ttagctttgg attgtactaa tcgttcaaga ccaggttatg ataatattac
      481 tgactttatt catgatatta aagtcaagta tccaaacaaa ttattaatgg ctgatatttc
      541 tacttttgaa gaagggaaag tagctgttga atcgggagta gattttgtgg gtacgacatt
      601 atctggttat acaccatata gccctaaaaa agataatcct gattttgagt tagttgaaag
      661 attggtaaaa gagcttgacg taccagttat tgctgaagga agaataagta ctccggaaca
      721 agctagaaaa atgttagatt taggtgctta cgcagtggtt gttggaggag ctatcactcg
      781 tcctttggaa atagcgaaga agtttattga ggtagtttag atgaatcaag aaatattaaa
      841 aaagagtaag attcaattga cagttgaaca tattcaaaaa tattggattt tatatttaat
      901 gatgattcca gcaactgttc tactaatttt atttacgtat ggaccaatgt acggcattat
      961 tatggccttt caagacttta ctgtcttcaa gggatatact ggaagtccat ttgtcggttt
     1021 aaaacatttt caaagattgt tctcagatcc tttgttttat agattgttca agaatacgtt
     1081 catggtaggg gttttagact ttttattctc tttcccagct ccgcttattt ttgcactcat
     1141 attaaacgaa gtcagaaaag taagatttaa gagtgtagtt caatctatta gttatcttcc
     1201 tcattttatt cccctagtgg ttatggttgg tattattttt gaactatttg gttcatatgg
     1261 tattattaac agtttacttt catcacttgg aatggagcca ataagtttct ttacaaaatc
     1321 tgaatggttc ttgcctctct acattggttc aggagtatgg aaaacaatag gttggggttc
     1381 tatcatttat atgggagcat taaccaatat agattcaact ttatatgaag cagcagatat
     1441 ggacggggct aatagatggc acaaaatgtg gcatgtaact ctaccaagtt taagacctac
     1501 agtagttact ttgtttatac taaatgctgg tggtatcatg caagtaggat ttgaaaaggt
     1561 attcttgatg tctagtcctg caacatatga agtatctgat gtattatcta cttatgttta
     1621 tagacaaggt attttaaatt ctgatttcag ttactcagct gcagtaggat tatttaataa
     1681 catagtagct ttgttatttg ttttattagc taataagatt gctaaaaaac ttggcgaaga
     1741 aggaattgta taaggggggt aaaatgattt tttcaaaaaa tacaaaaaag agtaatagag
     1801 acaaagaaac cttcgttgat tatctcttta tattcatttt aataataata accttactta
     1861 tgttgtatcc attatggtgg gtagtgatga cgtcactttc agaaccagtt tggctatcta
     1921 aaaacgttgt taaattattt cccttaaaaa tagatattac tgcatataag tttatttttg
     1981 gggattctaa actatggcaa gcatatggta atagtgtatt gtatgctgca ctatctacaa
     2041 ttgttagtgt tgcggtatgt agtatgtatg cctatccact tacaattcct gaaattaggg
     2101 gtaaaaaatt ctggaatact cttattttga ttccaatgtt ctttagtgga ggaatgatcc
     2161 cgctttatat acaagttgca aacctcggtt tattgaatac tgcttgggct cttgttttac
     2221 ctagtgctgt ttctacatat tatataattt tgtttagaac acagtttaaa tcaatcccaa
     2281 tggagcttcg tgagtctgct agaattgatg gggcaagtga atttagaatt ttttggaatt
     2341 tagtattacc attatcaaaa gttattttca tgattatagc actttattgc atagttggtt
     2401 catggaatag ttttactcct ccattacttt atttgaatga cgacactaag atgcctttat
     2461 ctatttattt gagaaattta gttgttacaa atacaactga tactgctgaa ttatcacttt
     2521 ctgcaggtaa tacatattac caacaaattg ctgctcaagg tggaggtatt ggtatgcgta
     2581 ttgctattaa gatgggtact attgttgtta gtgttattcc aattatgatg atttatccat
     2641 ttattcagaa acattttgtt aagggaatcc tgctaggttc tgtgaaaggt taataaggta
     2701 at
//
LOCUS       DAVLDI010000104         2690 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLDI010000104 DAVLDI010000000
VERSION     DAVLDI010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2690
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.105"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            324..1610
                     /locus_tag="VXD01_002188"
     CDS             324..1610
                     /locus_tag="VXD01_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV0602503.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            1625..1936
                     /locus_tag="VXD01_002189"
     CDS             1625..1936
                     /locus_tag="VXD01_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602504.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            2182..2690
                     /locus_tag="VXD01_002190"
                     /pseudo
     CDS             2182..2690
                     /locus_tag="VXD01_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
BASE COUNT          827 a          470 c          594 g          799 t
ORIGIN      
        1 atatcataat aataaataaa aaagcgatat tctagactgt atcaatcctt ttccattata
       61 ggagcaacag agtgggagta gtcatctaag gactaattta tatattttta cgagtcagta
      121 tcttgggata ctggttttta cttttttaga ctttttgact acttgttaaa actggggtaa
      181 ttttcgactg tttaatagtt attatgcaaa gtctaaaaga ttagaattgt caaaacaatc
      241 cgtctaggct tgattttatc ctttatttac tataaaatga gaaggaaaaa tgtcaaactt
      301 ttatattgca aataggagaa attatgacaa aaacattaaa acgtcctgag gttttatcac
      361 ctgcagggac tttagagaag ctaaaggtag ctgttcagta tggagcagat gctgtcttta
      421 tcggtggtca ggcctatggt cttcgtagcc gtgcgggaaa ctttactttc gaacagatgg
      481 aagaaggcgt gcagtttgcg gccaagtatg gtgccaaggt ctatgtagcg gctaatatgg
      541 ttatgcacga aggaaatgaa gctggtgctg gtgagtggtt ccgtaaactg cgtgatatcg
      601 ggattgcagc agttatcgta tctgacccag ccttgattat gattgcagcg actgaagcac
      661 caggccttga aatccacctt tctacccaag ccagtgccac taactatgaa acccttgagt
      721 tctggaaaga gctaggcttg actcgtgtcg ttttagcgcg tgaggtttca atggaagaat
      781 tagctgagat ccgcaaacgt acagatgttg aaattgaagc ctttgtccat ggagctatgt
      841 gtatttcata ctctggacgt tgtactcttt caaaccacat gagtatgcgt gatgccaacc
      901 gtggtggatg ttctcagtca tgccgttgga aatacgacct ttacgatatg ccatttggga
      961 aagaacgtaa gagtttgcag ggtgagattc cagaagaatt ttcaatgtca gccgttgaca
     1021 tgtctatgat tgaccacatt ccagatatga ttgaaaatgg tgtggacagt ctaaaaatcg
     1081 aaggacgtat gaagtctatt cactacgtat caacagtaac caactgctac aaggcggctg
     1141 tggatgccta tcttgaaagt tctgaaaagt ttgaagctat caaacaagac ttagtggacg
     1201 agatgtggaa ggttgcccaa cgtgaattgg caacaggttt ctactacggt ataccatctg
     1261 aaaatgagca gttgtttggt gctcgccgta aaatccctga gtacaagttt gtcgctgaag
     1321 tggtttctta tgatgatgcg gcacaaacag caactattcg tcaacgaaat gtcattaacg
     1381 aaggggacca agttgagttt tatggtccag gtttccgtca ttttgaaacc tatattgaag
     1441 atttgcatga tgccaaaggc aataaaatcg accgcgctcc aaatccaatg gaactattga
     1501 ctattaaggt gcctcaaccc gttcaatcag gagacatggt tcgtgcatta aaagaaggac
     1561 tcatcaatct ttataaggaa gatggaacca gcgtcacagt tcgagcttaa gaaaggaaaa
     1621 ggaaatgata gaggcacagg gtttcttagt ggataagcaa acaagatgca ttcattacca
     1681 tagcaagctg gatattattg ctttacaatg ctatgattgt aaaaagtatt atgcttgtta
     1741 tcggtgtcat gattcattag aaaatcaccc ttttgagccg tatcccttat ctttgataca
     1801 ggataagcct attttatgtg gtgtttgtct aaaactacta acatataagc aatataaaga
     1861 aagcttaagt tgcccctttt gtttttctcg ctttaatcca ggttgccaaa atcataagga
     1921 acgctatttt aaatagcaaa tcatctagtt ttgaagtagg agaaaactca attccaagag
     1981 aaaatgaagt aaatcttccc acaataaaac gcataatatc aagattgttc aatacctgat
     2041 actatgcgtt tttaagattt taaagacttt tttcctttat ctggtatttt gactacttgt
     2101 taaaactggg tcaattttca actgtttaac agttattatg caaagtctaa aagattagaa
     2161 ttgtcaaaac aatccgtcta gagtatgcgt gatgccaacc gtggtggatg ttctcagtca
     2221 tgccgttgga agtacgacct ttacgatatg ccatttggga aagaacgtaa gagtttgcag
     2281 ggtgagattc cagaagaatt ttcaatgtca gccgttgaca tgtctatgat tgaccacatt
     2341 ccagatatga ttgaaaatgg cgtggacagt ctaaaaatcg aaggacgtat ggagtctatt
     2401 cactatgtat taacagtaac caactgctac aaggcggctg tggatgccta tcttgaaagt
     2461 cctgaaaagt ttgaagctat caaacaagac ttggtggacg agatgtggaa ggttgcccaa
     2521 cgtgaactgg ctacaggatt ttactatggt acaccatctg aaaatgagca gttgtttggt
     2581 gctcgtcgta aaattcctga gtacaagttt gtcgctgaag tggtttctta tgatgatgcg
     2641 gcacaaacag caactattcg tcaacgaaat gtcattaacg aaggggacca
//
LOCUS       DAVLDI010000105         2446 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLDI010000105 DAVLDI010000000
VERSION     DAVLDI010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2446
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.106"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..795)
                     /locus_tag="VXD01_002191"
     CDS             complement(<1..795)
                     /locus_tag="VXD01_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HEV0602505.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEETKAIPNVEFMWITDGQGWYKAKNNLRE"
     gene            complement(782..1552)
                     /locus_tag="VXD01_002192"
     CDS             complement(782..1552)
                     /locus_tag="VXD01_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0602506.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(1578..2432)
                     /locus_tag="VXD01_002193"
     CDS             complement(1578..2432)
                     /locus_tag="VXD01_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEV0602507.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELIPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
BASE COUNT          794 a          485 c          293 g          874 t
ORIGIN      
        1 ttctcgtaaa ttattcttag ccttatacca accttgtcca tcagtaatcc acataaactc
       61 aacattagga atagctttag tttcttcagc aatcattttg taagatctag ccgtctcatt
      121 taattttgaa ccacttcctg aataaaaatt aacctcaatc agataaagca cttgttcatt
      181 ttttatgaca aaatcaaaac gtttcacagt attcccatca ttcgtaatag cagataaatc
      241 gacagaaaaa atttcctcta tttcattttg ttcaatctct ttaaataaat tctctcctaa
      301 aatataccct tcagcttcaa gatagctttg aacaatattt tccatcgcat ctccagtccg
      361 atttttgcgc ccattagtat ccataccaac ctcaacacct gtaacgtagt caactaaatt
      421 tgatactaaa tgattttgca ataaatcaaa tatacctgat ttttccaaaa acatagtata
      481 ttcttcaata ctatagtttc gtttactaaa atcaaaatag aaatctttta tcggatcctt
      541 aacaataatc gtatctctca aacgtttagc aataagtaga ggcacaactt tcaaaatttc
      601 tggataattt tgatataagt ctaaaaaatc ctcttgtata tttttactac caataagact
      661 attcataata tttagagcaa cttttatact agatacattt ttataaacct taggaaaatc
      721 tgtataataa gtccagtcag ctactgtgtc ggtcatcgtt gacaaccact catcaaaatt
      781 tctagtttgt ttcattttct gcctccaacc tcttccttgc aatttttaaa tattcttttt
      841 cagcatcgat acctataaat cttctaccta accgcttcgc aacaacaccc gtagtgccac
      901 taccaacaaa tgggtctaga atatagtcac cctctttagt agaggctaaa ataatacgtt
      961 ctaacaaata ctctggtttt tgagttggat gtttcccagc ccatttttca actttctttg
     1021 ttaaagaacc ggtccagaca tctttcattt gttttccatc attcaattct ttcattaaat
     1081 cataattgta gtaatgacga gcttttttat cattttttct ggcccataaa atggtttcag
     1141 tagaatgggt aaaataacga caagataaat tgggggcagg gtttgttttc tgccaagtaa
     1201 tattattcag aattttaaaa ccttcttgtt ctaatgccat tccaactgag tatatgttgt
     1261 gcaaactacc tgaaatccat accgtcccat taggcttcag aacttctttt gctaggcgaa
     1321 tccatttacg attaaactca tgtttttctt cgaatgaaga aattttatcc caatctcctt
     1381 tatcaacaga aactacttgt cccccagaat tagatattcc accattactt aaaaaataag
     1441 gtggatcagc aaaaatcata tccatacttt ctggtttcat ttttgataag aacttgaacg
     1501 tatctgaatg aacaagaatc atcttatttt tattgtagta tggttttgtc ataagaacac
     1561 ctccatactt atattcgtta tttttcataa tttgtgacta taatttcaga aatttttcct
     1621 cgacttgaag attttgctcc attagttcgg gtagcttcaa cataatgtat attaaaatcc
     1681 ttatacaact cctctactaa agcactagaa gaatttgata acataacata agctcctgta
     1741 tcactcaatc tcttaaaggc atctcttaat cttacttgat ctgcaaaaga gaatccctca
     1801 tgagtataag acgtaaatgc actcgtctca gacaatggaa tatatggagg gtcaaaatac
     1861 acaaaatctc ctgttcgaac atctacaatt gccttttcaa aatctcccac tttaatttct
     1921 agttgattgt tatttatata aactgaaata gcagatatca attcctcatc aacaatttta
     1981 ggattcttat aacgtccata tggaacatta aattgattct tagaattcac acgatataga
     2041 ccattaaagt tcactctcaa catatataga atacgtgcag ctctttgtac ttcggacatc
     2101 atatctattc tttcatcacg atctgcagaa cgtaaatcta aataatattc ttttgaatta
     2161 tattcctgat gaactttcaa aatttcaatc aattcttgag gattgtcctt aatttgttga
     2221 tagcaattta ttagttcagc gttaaaatca ttaataactg catctttagg agccaaatca
     2281 aaaaataaag ctccacctcc aacaaaaggt tcgaaatacc tgttataggt tttaggtatt
     2341 aattctctaa taacaggcaa taattgtctt ttaccacctg tccatttcgt gaacggttgt
     2401 aaagtaactt tctttatttc ttttatcttc atgcttttaa ttatac
//
LOCUS       DAVLDI010000106         2400 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLDI010000106 DAVLDI010000000
VERSION     DAVLDI010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.107"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            82..837
                     /locus_tag="VXD01_002194"
                     /pseudo
     CDS             82..837
                     /locus_tag="VXD01_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(971..1058)
                     /locus_tag="VXD01_002195"
     tRNA            complement(971..1058)
                     /locus_tag="VXD01_002195"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1022..1024),aa:Ser,seq:gct)
     gene            complement(1065..1138)
                     /locus_tag="VXD01_002196"
     tRNA            complement(1065..1138)
                     /locus_tag="VXD01_002196"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1102..1104),aa:Ile,seq:gat)
     gene            complement(1174..1244)
                     /locus_tag="VXD01_002197"
     tRNA            complement(1174..1244)
                     /locus_tag="VXD01_002197"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1210..1212),aa:Gly,seq:tcc)
     gene            complement(1264..1336)
                     /locus_tag="VXD01_002198"
     tRNA            complement(1264..1336)
                     /locus_tag="VXD01_002198"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1301..1303),aa:Phe,seq:gaa)
     gene            complement(1340..1413)
                     /locus_tag="VXD01_002199"
     tRNA            complement(1340..1413)
                     /locus_tag="VXD01_002199"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1377..1379),aa:Met,seq:cat)
     gene            complement(1427..1516)
                     /locus_tag="VXD01_002200"
     tRNA            complement(1427..1516)
                     /locus_tag="VXD01_002200"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1478..1480),aa:Ser,seq:tga)
     gene            complement(1527..1600)
                     /locus_tag="VXD01_002201"
     tRNA            complement(1527..1600)
                     /locus_tag="VXD01_002201"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1564..1566),aa:Ile,seq:cat)
     gene            complement(1614..1687)
                     /locus_tag="VXD01_002202"
     tRNA            complement(1614..1687)
                     /locus_tag="VXD01_002202"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1651..1653),aa:Met,seq:cat)
     gene            complement(1693..1766)
                     /locus_tag="VXD01_002203"
     tRNA            complement(1693..1766)
                     /locus_tag="VXD01_002203"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1730..1732),aa:Pro,seq:tgg)
     gene            complement(1782..1855)
                     /locus_tag="VXD01_002204"
     tRNA            complement(1782..1855)
                     /locus_tag="VXD01_002204"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1819..1821),aa:Arg,seq:acg)
     gene            complement(1865..1950)
                     /locus_tag="VXD01_002205"
     tRNA            complement(1865..1950)
                     /locus_tag="VXD01_002205"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1914..1916),aa:Leu,seq:taa)
     gene            complement(1958..2029)
                     /locus_tag="VXD01_002206"
     tRNA            complement(1958..2029)
                     /locus_tag="VXD01_002206"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1995..1997),aa:Gly,seq:gcc)
     gene            complement(2052..2124)
                     /locus_tag="VXD01_002207"
     tRNA            complement(2052..2124)
                     /locus_tag="VXD01_002207"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2089..2091),aa:Thr,seq:tgt)
     gene            complement(2143..2224)
                     /locus_tag="VXD01_002208"
     tRNA            complement(2143..2224)
                     /locus_tag="VXD01_002208"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2188..2190),aa:Leu,seq:tag)
     gene            complement(2230..2302)
                     /locus_tag="VXD01_002209"
     tRNA            complement(2230..2302)
                     /locus_tag="VXD01_002209"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2267..2269),aa:Lys,seq:ttt)
     gene            complement(2327..2399)
                     /locus_tag="VXD01_002210"
     tRNA            complement(2327..2399)
                     /locus_tag="VXD01_002210"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2364..2366),aa:Asp,seq:gtc)
BASE COUNT          704 a          599 c          486 g          611 t
ORIGIN      
        1 gtgtaatttt agaaatctgc ctaagattat gtcttgggac gttgaaacag tccggggagt
       61 gactgtttca atcgggagat ggagatgagc tttattgcgc aagattttga aaagctcgat
      121 atcatcactg ttcttgaagg tagaacacaa gctgtcatcc gagatcactt tcttaaatat
      181 gatagagccg tccgatgtcg cgtcaaaatt attactatgg atatgtttag tccttactat
      241 gacttagcta gacaactttt cccatgtgct aaaatcgtgt tggatcgctt tcacattgta
      301 caacatctta gccgtgctat gagtcgtgtg cgtgttcaaa tcatgaatca gtttcatcga
      361 aaatcccatg aatacaaggc tatcaagcgc tactggaagc tcatacaaca ggatagtcgt
      421 aaactgagtg ataagcgatt ttatcgtcct acttttcgta tgcacttaac caataaagag
      481 attttaaaca agcttttgag ttattcggaa gacttgaaac accactatca gctcttactt
      541 tttcacttcc agaataagga accagagaaa tttttcgaac ttattgagga caatcttaag
      601 caggttcatc ctatttttca gactgtcttt aaaaccttcc tcaaagataa agaaaagatt
      661 attaacgccc ttcaactacc ctattctaat gccaaactgg aagcgaccaa taatctcatc
      721 aaacttatca agcgcaatgc ctttggattt cggaactttg aaaacttcaa aaaacggatt
      781 ttcatcgctt tgaacatcaa aaaagaaagg acaaaatttg tcctttctcg agcttagctt
      841 ttcttcaacc cactacagtt gacaaagagc cataaaaata acttcagatt agtaattcaa
      901 ttaagtttta cggatctgaa gctttattgt ctctaaaaat aaaaaagaga gttacaaact
      961 ctcattaaaa cggagaataa gggattcgaa cccttgcgcc agttacccga cctaacgatt
     1021 tagcaaaccg tcctcttcag cctcttgagt aattctccaa ttaatgggca cgagtggact
     1081 cgaaccaccg acctcacgct tatcaggcgt gcgctctaac cacctgagct acgcgcccaa
     1141 gttaaaaaac ttggtaattt gaacaaagtt caaagcgggt gacgagaatc gaactcgcga
     1201 caacagcttg gaaggctgta gttttaccac taaactacac ccgcataaat actatcaata
     1261 aaatggcgcg agacggaatc gaaccgccga cacatggagc ttcaatccat tgctctacca
     1321 actgagctac cgagccttat tgcgggagca ggatttgaac ctacgacctt cgggttatga
     1381 gcccgacgag ctaccgagct gctccatccc gcgttaataa tataaaagga ggatgtggga
     1441 ttcgaaccca cgcacgcttt tacacgcctg acggttttca agaccgttcc cttcagccgg
     1501 acttgggtaa tcctccaata ttcaaatgga ccttgtagga cttgaaccta cgaccactcg
     1561 gttatgagcc gagagctcta accagctgag ctaaaggtcc aacaagatca ttatagcggc
     1621 gaaggggatc gaacccccga cctcccgggt atgaaccgga cgctctagcc agctgagcta
     1681 caccgccatg aatcgggaag acaggattcg aacctgcgac accttggtcc caaaccaagt
     1741 actctaccaa gctgagctac ttcccgagtt aaatagaaaa atgcacccta gaggagtcga
     1801 acctctaacc gcctgattcg tagtcaggta ctctatccag ttgagctaag ggtgctccat
     1861 attatgccga ggaccggaat cgaaccggta cgatcgttac caatcgcagg attttaagtc
     1921 ctgtgcgtct gccagttccg ccaccccggc ctctctaagc gaacgacggg attcgaaccc
     1981 gcgaccccca ccttggcaag gtggtgttct accactgaac tacgttcgca ctgttttctt
     2041 ctatctaaaa atgccggcta catgacttga acacgcgacc ctctgattac aaatcagatg
     2101 ctctaccaac tgagctaagc cggctcattt gttatatctt aatgcgggtt aagggacttg
     2161 aacccccacg ccgttaagcg ccagatccta aatctggtgc gtctgccaat tccgccaaac
     2221 ccgcatatat gacccgtact gggctcgaac cagtgaccca ttgattaaaa gtcaattgct
     2281 ctaccaactg agctaacgag tctaaaataa cttgcgttac cttaaacggt cccgacggga
     2341 atcgaacccg cgatcttcgc cgtgacaggg cgacgtgata accgctacac tacgggacct
//
LOCUS       DAVLDI010000107         2371 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLDI010000107 DAVLDI010000000
VERSION     DAVLDI010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2371
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.108"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..550
                     /locus_tag="VXD01_002211"
     CDS             <1..550
                     /locus_tag="VXD01_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602508.1"
                     /translation="WIVVHSGFIKYIKKNHRPVIITTWLVISLLSIIFFFKHIINNSE
                     SYTHRVLGIVNFFKYYESSKFHLFFGDAELAFGDMTKGYTHNIRSVLGWDGTVEMPLL
                     SVMIKNGYVGLIGYGVVLFKFISSVLSMEDRRVKNIGLSILIPLLLSAMVENYIVNIS
                     FVFMPVCFCILCSIKNIEFKNN"
     gene            560..1528
                     /locus_tag="VXD01_002212"
     CDS             560..1528
                     /locus_tag="VXD01_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV0602509.1"
                     /translation="MKKVSIILPVYNVEQYIKKCLESIQQQTYPNLEVIIVNDGATDK
                     SVEYCEQICKIDSRFSVTHKENGGLSDARNVGIDKAKGDYLIFVDSDDFVSQDMVSYL
                     VSSMENNEADIAICDPAHYYSDRQNNDLNIFYPASSVKVYEKTEALCEMFYQKSFLVS
                     AWAKIYKKELFDDIRFPVGKLFEDSAVMYLLFEKCEKIVYSNAKLYAYVHRDNSITTK
                     KFSDKDLDILDISNTILDHYSGNFRVYKAAVSYKVSACFRILLNSSSEKKYNQIQKDC
                     MTYILRNWRNVLFDKNVRLKNKLALISITLFNPFVKFIYSKVNRWE"
     gene            1535..>2371
                     /locus_tag="VXD01_002213"
     CDS             1535..>2371
                     /locus_tag="VXD01_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001045980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 61 protein"
                     /protein_id="HEV0602510.1"
                     /translation="MNKYEERYQEDLSKNDFEKLINRRYLSDKELQVEYVKKGTVLPP
                     KVFEMKLSNKLGLQKALHGKGGVVDSKGNYVELSEQKAVGMRNRVYGSYKFNHKNLAI
                     RNEKVIYLNYFINQWGHFLLDVVGRLWYPLLKDTDTKLDYTCYAGTETKLEGNYLEFL
                     ELLGIDKSRLILINRPTQFSEIIIPESSILPGEYYTKEYKMLFNSLVANVKLDNNLES
                     KKIYCSRARLDLAKGKEFGENGIEKVFLKNGYTPVYMETMSLKEQIRTLLSATTIVLT
                     SGS"
BASE COUNT          859 a          295 c          420 g          797 t
ORIGIN      
        1 ttggatcgtt gttcatagcg gatttattaa atatataaag aaaaatcaca gaccagtaat
       61 tataacgaca tggttagtaa tttctttatt atctataata ttttttttca aacacattat
      121 aaataatagt gaatcctata ctcatcgtgt tttgggtatt gttaattttt ttaaatacta
      181 cgaatctagc aaatttcatt tattttttgg tgatgctgag ttagcctttg gtgatatgac
      241 gaaaggttat actcacaata taagaagtgt tttaggttgg gatggaactg tggaaatgcc
      301 gttgctaagt gttatgataa aaaatggtta tgtcggctta atagggtatg gagtagtctt
      361 atttaaattt atatcctctg tattatctat ggaagataga agagtaaaaa atattggctt
      421 atccattcta atacctctac ttctatcagc aatggttgaa aattatatcg ttaatattag
      481 ctttgtattc atgccggtct gtttttgtat tttatgctca ataaaaaata tagaatttaa
      541 aaataattga aagtgattta tgaaaaaagt aagtattatt ctacctgtct acaatgttga
      601 acagtatata aaaaaatgct tagaatcaat tcaacaacaa acttatccaa atttggaagt
      661 aatcattgtt aatgacggag caaccgataa aagcgttgaa tactgtgagc aaatttgtaa
      721 gatagattct aggttttctg tcactcacaa agaaaatggt ggactttccg atgcaagaaa
      781 tgtcggtata gataaagcca agggagatta cctcattttt gttgacagtg atgattttgt
      841 ctctcaagat atggtatctt atttagtatc tagtatggag aacaatgagg cagacattgc
      901 tatttgcgat cctgctcatt attatagtga ccgtcaaaac aatgatctta atatttttta
      961 tccggcatca agcgttaagg tttacgaaaa aacggaagct ctatgtgaga tgttttatca
     1021 aaaatctttt ttggtatctg cttgggctaa gatatataaa aaggaactat ttgatgatat
     1081 cagattccct gttgggaagt tatttgaaga tagtgctgtt atgtatctgc tttttgaaaa
     1141 atgtgaaaag atagtatatt ctaatgcgaa attatatgcc tatgtgcata gagacaatag
     1201 tattacaaca aagaagtttt cagataaaga tttagatatt ttagacattt caaatactat
     1261 tcttgatcac tatagtggga actttagagt ttataaagcg gcagtttcct ataaagtttc
     1321 ggcatgtttt agaattttgt tgaactcatc ttcagaaaaa aaatataatc aaatacaaaa
     1381 agattgtatg acatatattt tacgaaattg gagaaatgtg ttatttgata aaaatgtccg
     1441 attaaagaac aagcttgcct tgatttctat aactcttttc aatccttttg ttaaatttat
     1501 ctatagcaaa gtaaacagat gggaataata gcaaatgaac aaatatgaag aaagatatca
     1561 ggaagattta tctaagaatg attttgagaa actaatcaat agaagatacc tatcggataa
     1621 agaactacaa gttgaatatg taaaaaaagg aacagtgtta cctcccaagg tctttgaaat
     1681 gaaactatca aataaacttg gtctacaaaa agctttgcat gggaaaggtg gtgttgtaga
     1741 ttcaaagggg aattatgttg aactttctga acaaaaagca gttgggatga gaaatcgagt
     1801 ctatggatct tacaaattta accataaaaa tttggctatc agaaatgaaa aagttattta
     1861 cctaaactat ttcataaatc agtggggaca ttttttacta gatgttgtgg ggagattatg
     1921 gtatccatta ctaaaagata ctgatactaa actggattac acatgttatg ctggtacaga
     1981 aacgaaactt gaaggaaact atttagagtt tttagaactc ctcggtatag ataaatcacg
     2041 cttaattttg ataaatcgcc caactcaatt ctcagagata attatacctg aaagttcaat
     2101 tctgccaggt gaatattata caaaagaata taaaatgctt tttaattctt tagtagcaaa
     2161 tgttaaatta gataacaatt tagaatcaaa aaaaatttat tgttcacgag ctaggctaga
     2221 tttagcaaaa ggtaaagagt tcggtgagaa tggtattgaa aaggtcttct taaaaaacgg
     2281 ttatactcca gtttatatgg aaacaatgtc tttgaaagaa caaataagaa cgctattatc
     2341 agctacaaca atagtattaa ctagcggttc g
//
LOCUS       DAVLDI010000108         2345 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVLDI010000108 DAVLDI010000000
VERSION     DAVLDI010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2345
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.109"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..191
                     /locus_tag="VXD01_002214"
     CDS             <1..191
                     /locus_tag="VXD01_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEV0602511.1"
                     /translation="KMMKPQKEIYLSLVNKYQLDIKDCIFLDDLEENVEAARTLGIKA
                     FQIKERKEISNILKDLLN"
     gene            201..2228
                     /locus_tag="VXD01_002215"
     CDS             201..2228
                     /locus_tag="VXD01_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV0602512.1"
                     /translation="MVTIKDIARVSGVSHGTVSNVLNKKGNVSAAKIKLVEETAKKLG
                     YNMNSQAQFLRKGASSKCFFLLFNNARKKYAEYFAEIDQLSLDVEYVYLHKFSEIKNK
                     ISAILSENPQFIVCLGFSPKRFVDIEDNIPIFEVDTYQSNKTLSSFDSDKIFEIVLEL
                     VRTEKLSNLYFISLTNEKEHSLFEYLTQKIKNSTHIQVQERLQLLSLYPTLKNFAKYD
                     CIFVDDEDLMHTLLDLFDWFTIIDRPKICLIGSRVWFEKRNLFYIHLDYRILALNTAE
                     NLESGNSSIVPVKDGKQILIDQLFDGECDDIYLLTVHSPMNKALEILSEKYKQISGKN
                     IKIIEKRYDELLEMIESGDVSSSFDMIRMDMAWLPTFGKKYFQEITSFRQTKSINQNI
                     SKSVSREYMYIDQKQYTFPLDVSSQILVYRKDLFEDSFLQRRYFEKTKRKLTVPKSYQ
                     EFDELSEFFTLTENPFSPTLYGHSLALSSSVRAACEFIPRFRERLAQSRMNLAVLPQV
                     LTEYEKSYQFTEKSFNSSWNDFVTNLNSGKTSMEIIFSNYTSPLFDGLNVSAQFEFAT
                     ATIPGNTPVIGGGSIGISKYSNRVEECLNFINWLYSEEISILLTSLGGFLPSKYVMQN
                     RMLQFQYPWLSSLEDTFSIGSRTKWYGFNTDFRFEQMLGQELIESVKHRYG"
BASE COUNT          849 a          279 c          385 g          832 t
ORIGIN      
        1 ttaaaatgat gaaaccacaa aaagaaattt acttgtcatt agttaataaa tatcaattag
       61 atataaaaga ttgtatattt ttagatgatt tagaagaaaa tgtagaagct gcaagaactc
      121 taggtattaa agcatttcaa attaaagagc gtaaagagat ctcaaatata ctaaaagatc
      181 tcttaaacta gaggttaatt atggttacaa taaaagatat tgcaagagtg tctggagtct
      241 cacatgggac agtttcaaac gttttaaata aaaaaggtaa tgtctcagca gctaaaataa
      301 agttagtaga agagactgcg aaaaaattgg gttataatat gaattctcaa gctcagtttc
      361 ttcgaaaagg cgcttctagt aaatgttttt tcttgttatt taataatgca cgcaaaaagt
      421 atgctgagta ttttgcagaa attgatcagt tatctttaga tgtagaatat gtttacttac
      481 ataaattctc agagattaaa aataagatat ctgcaatttt aagtgaaaat cctcaattta
      541 tagtttgctt aggtttttct ccaaaaagat tcgttgatat tgaagataat attccgattt
      601 ttgaagtaga tacatatcaa tctaataaaa ctttatcttc ctttgatagt gataaaatat
      661 ttgagattgt acttgagttg gttcggactg aaaagctatc taatttatat tttatttcac
      721 ttactaatga aaaagaacat tctttatttg aatatttaac tcaaaaaata aaaaactcaa
      781 ctcatataca agtgcaagaa cgtttacaat tgttgtctct atatcctact ctaaaaaact
      841 ttgcaaagta tgattgtata tttgttgatg atgaagattt gatgcacacg ctattagact
      901 tatttgattg gtttactata attgatagac caaaaatatg tttgataggt tcacgtgttt
      961 ggttcgaaaa aagaaatctt ttttatatac atttagatta tagaatattg gcactcaata
     1021 ctgccgaaaa tttagaaagt ggaaatagtt caattgtacc agttaaagat ggcaaacaaa
     1081 ttttaattga tcaattattt gatggagaat gtgatgatat ttatttactt actgtccatt
     1141 caccaatgaa taaagcctta gaaattttat cagaaaagta taaacaaatt tctgggaaaa
     1201 atattaaaat tatcgagaaa agatatgatg aacttttgga gatgattgag tctggcgatg
     1261 tttcatccag ttttgatatg attagaatgg atatggcttg gcttccaaca tttgggaaaa
     1321 agtattttca agagattaca agctttagac aaacaaaaag tattaatcaa aatatttcta
     1381 agtcggtgtc tcgagaatat atgtatattg atcagaagca gtatactttt ccattggatg
     1441 ttagtagtca gattttagta tatagaaaag acttatttga agattcattt ttacaaagac
     1501 gatactttga aaaaacaaaa agaaaattaa ctgtaccaaa aagttatcaa gagtttgatg
     1561 agttaagtga attttttaca ttaacagaaa atccattttc acctacactt tatggccata
     1621 gtttagcttt aagttcttca gtgagagcag catgtgaatt tattcctcgg tttcgtgaga
     1681 gattagcaca atctagaatg aatcttgctg tacttcctca ggttttaact gagtatgaga
     1741 aaagttatca gtttaccgaa aaatcattta attcttcgtg gaacgatttc gttacgaact
     1801 taaacagtgg taaaacttca atggaaataa ttttttcaaa ttatactagt ccattatttg
     1861 atggtctcaa tgtttctgct cagtttgagt ttgcaactgc cactatacct ggtaatactc
     1921 ctgtgatagg tggtggctca attggaattt ctaaatattc aaatagagtg gaagaatgtc
     1981 taaactttat taattggtta tattctgaag agatttctat tttactaaca tctctgggtg
     2041 gttttttacc atcaaagtat gtcatgcaaa ataggatgtt acaatttcaa tacccatggt
     2101 tatctagttt agaagataca tttagtattg ggagtagaac aaaatggtac ggctttaata
     2161 ctgattttag atttgagcag atgttagggc aagagttaat agaaagtgtg aagcatagat
     2221 atggataaat taatactaaa tttttattac tagtttattt attattgttt aaaattaaag
     2281 attcaagtaa acaccaatta tatttaaaat tattattttg acatttttct attgcaaagt
     2341 tattt
//
LOCUS       DAVLDI010000109         2192 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLDI010000109 DAVLDI010000000
VERSION     DAVLDI010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2192
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.110"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(1..344)
                     /locus_tag="VXD01_002216"
                     /pseudo
     CDS             complement(1..344)
                     /locus_tag="VXD01_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005501.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(402..1115)
                     /locus_tag="VXD01_002217"
     CDS             complement(402..1115)
                     /locus_tag="VXD01_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV0602513.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAEFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1574..1954)
                     /locus_tag="VXD01_002218"
     CDS             complement(1574..1954)
                     /locus_tag="VXD01_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV0602514.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLVFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
BASE COUNT          727 a          422 c          342 g          701 t
ORIGIN      
        1 cgtaggcata ttttgctaca tgatctaggt atatatcaaa aaaagtcatg aggaaaatct
       61 cccatacagc cattacgatt catattgagg ctatattttc gattagtaag ataattcgga
      121 aatatatttc ctattactct aagattatct acttgtgaat cccttctccc aatataatcc
      181 ccttctttga ctaatgatgg agatttccaa gtaaaaatta aatcgccaga gaaatttttc
      241 ttatcaaaaa acttaaaaag agattgataa atactatttg ctaattgaca agtgtcagat
      301 gtaaattcat aagtaacagc ttcattaaaa tcaacttcag acatttcaat gtactcttca
      361 atagtaatat tagctttttt gtagtcatta gctcgtctcc tttaaaatgt gatcttttca
      421 agaatatttt tatctaaaca atccagcaag tcttggtaag aatagacttc gtaagtcggc
      481 tgggcttgtg tgtgattttc gaggtgatga ggattatacc agatagtgtc aatccccgca
      541 ttattgccac cttgaatgtc ggcagttaga gaatctccaa tcatcagcgt cttttcttta
      601 ctaaattcag caatttgctg gccaatcttt tcataaaaga gagcatccgg cttttgagtt
      661 tgcaactgtt ctgagataaa gacttgattg aaataaggtg ctagaccaga ttgagccaaa
      721 cgtcctgtct gaatggcagt aatgccattt gtcgcagcat acaagttata atcacgctca
      781 atgaggctgt ccaagagatc atgagcgccc gatagtgttt gtccctgctg ggcgaggtaa
      841 aattggtaac gctgggcaag aaaactaccg tctttttcct gtccaaaatg agcaaataaa
      901 cgagaaaagc gcgtgttaac cagctcttgt ttactgattt tcttcagctc caagtctttc
      961 cagagagcct tgttcatagg aacgtaataa tctttataag cctgaatatc cgcaactcct
     1021 tcttctttta gaagttgggt caaagccaca tcctcagcag catcaaaatc aagaagagtg
     1081 tggtcgaggt cgaagagtag aaatttgtag aacaatttga ggttttcctt tctgaaaatt
     1141 cattaagaac attatatcat aaagcacctc atacaattaa ctaatttaat cacttaaaaa
     1201 aaattcgaac actttctata caactgacag ctcaaatctt tcagaataga acaatactaa
     1261 ctatcgagca ccccgtcttc ataaatatat gtgtaattct agacctagaa ttcttataaa
     1321 ctaaatgctt tcatactctt ccaagtaatt gattgcctta aattttaatt tttgaaggat
     1381 tctaaagcta gaatagtccc atcacaatca gttttgattg attcacaatt tagaaacact
     1441 atagtttcac tcctgttaaa ataaaaagga actgcataaa gcaatccctt tctgattttg
     1501 aaatcattta cttaacattt tatagttgag ataatcaata gcttacctat aaaaagagtt
     1561 atagtaaaat tccttattta ttgatttcaa gctccgctaa ctgtatttga ataactgaca
     1621 gttctgcacc agcctgaaga agagcagctg cattataggc accttctaca attggaaccc
     1681 tgttgatgat gatactttta tcactgaaat cagtcaccat ttttaagttc attttagcag
     1741 aacctaggtc aaaaaataca agtaaagtat ctgctggatt ttcggaaaca accctatcta
     1801 cttgatcaaa actcgttcca attcctccgc cctcggttcc tcctacataa gtaatcggaa
     1861 catctttagc tactttacta atcagttcaa caacaccttc tgcaatgtgt ttggaatgtg
     1921 aaacgataac aagaccaata ccaatacttt ccatcaaacc actccagttt ctaaaatagc
     1981 agtaaagagt aatcctgatg agaatgatcc aggatcaata tgtccaagaa accacatgct
     2041 cctaagacaa gagctaacag actggccgtc aataatagta ttgttctttt tttcatcatt
     2101 actccttaac tagtgtttaa ctgattaatt agccagtaaa tagtttatct ttatttacac
     2161 tatctgttaa gatatagtaa aatgaaataa ga
//
LOCUS       DAVLDI010000110         2191 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLDI010000110 DAVLDI010000000
VERSION     DAVLDI010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2191
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.111"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            21..932
                     /locus_tag="VXD01_002219"
     CDS             21..932
                     /locus_tag="VXD01_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0602515.1"
                     /translation="MLLIGDESYSFSTLIKVLNSETVPGASFSIMEIRLPKLLAGIIA
                     GWSFGLAGFIFQTMLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCGL
                     TSSLILFLLAKKDGFSAARLIILGIGFQAVTRAGTSFLLLKVARYELQEVMRWLSGSL
                     SFTKLDDIPLVLIVSIIATILVLFFNKRLEIIELGEEIAIGLGANPELSRLVLIFCAV
                     SLTAFSTSITGPIACISFLAGPIALNIGKKRSPILAGLVGVLLVLLSDIFSQNILPAR
                     YPVGVVTGLLGSPYLIYLLIKMNRRNI"
     gene            932..1726
                     /locus_tag="VXD01_002220"
     CDS             932..1726
                     /locus_tag="VXD01_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602516.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLVKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
BASE COUNT          806 a          333 c          362 g          690 t
ORIGIN      
        1 taatcagtct atcatttttc attttactta tcggagatga aagttattct ttttcaactt
       61 tgattaaagt cttaaatagt gaaactgttc ctggagctag tttttcgatt atggaaatta
      121 gattaccaaa attattagca ggaattatag ctggctggtc ttttggattg gcaggattta
      181 tctttcaaac tatgttaaga aatcctcttg caagtcctga tataatcggt gtcacaagtt
      241 cttcatctat tgcagcggtc ttttgcatat tggtattaaa aacaaatagt ttaactactg
      301 gaattatttc aataacttgt ggactaacat catctttaat attattttta ctagctaaaa
      361 aagatggttt ttcagcagca agactgataa tattaggtat tggttttcaa gctgtcacaa
      421 gagcaggcac ctcattttta ttgttgaaag tagcaagata tgaattacaa gaagttatga
      481 gatggctcag tggctcttta tcttttacaa agttagatga catacctctt gttctaatag
      541 taagtattat tgctactata ttagttttat tttttaataa aagactagaa attattgaac
      601 ttggtgaaga aatagcaatc ggacttggtg caaatcccga gctttcaagg cttgttttaa
      661 ttttttgcgc tgtatcttta actgcttttt ctacttcaat tacaggacca atagcttgta
      721 tatctttttt agctggtccc atagccttaa atattggcaa gaaaagaagc ccaatattag
      781 ctggattggt tggagtttta ctagttttgt tatcagacat attctctcaa aatattttac
      841 cagctagata tccagtaggt gttgtaactg gcttgttagg ttcaccatac ttaatatatt
      901 tactaataaa aatgaacagg aggaatatat aatgaaaggt ctgtggtcaa ataatcttac
      961 ctgcggttat gatgaaaaaa taatcttgga aaatataaat ataaaaatac ctgaagaaaa
     1021 aatatcagtt attattgggt caaatggttg tgggaaatca acactcatta aaaccttgtc
     1081 tcgacttata aagccattag agggagaagt attgcttgat aataaatcaa ttaattctta
     1141 taaagaaaaa gatttagtaa aacacatagc tatattacct caatctccaa taatccctga
     1201 atcaataaca gtagctgatc ttgtaagccg tggtcgtttc ccctacagaa agccttttaa
     1261 gagtcttgga aaagatgacc ttgaaataat aaacagatca atggttaagg ccaatgttga
     1321 agatctagca aataacctag ttgaagaact ttctgggggt caaaggcaaa gagtatggat
     1381 agctctagcc ctagcccaag atacaagtat cctactttta gatgagccaa ctacttactt
     1441 ggatatctca tatcaaatag aactattaga cctcttgact gatctaaacc aaaaatataa
     1501 gacaaccatt tgcatgattt tgcacgatat aaatctaaca gcaagatacg ctgattacct
     1561 atttgcaatt aaagaaggta aacttgttgc agagggaaag cctgaagata tactaaatga
     1621 taaactagtt aaagatatct ttaatcttga agcaaaaatt atacgtgacc ctatttccaa
     1681 ttcgcctcta atgattccta ttggcaagca ccatgttaac tcttaataat tgaatattgg
     1741 aattcattta aaagtcgcaa attttgaact gaccctcaaa agttaggcca aaaaactaac
     1801 taaaggaggt cagtttttta atggcaaata cagcacagaa tttaagataa aattagtaaa
     1861 agaatatcat gaatgaaaaa taggatatag agaataacag caatattaaa aagatcagga
     1921 ctgataataa acaaaaagaa agtacaacga ctagttcaaa agctaaaact tcaagtaaaa
     1981 agttattcaa gaaaatctag aaaatactca tcctacaaag gacaggtagg aaaaatatca
     2041 gacaacaaaa taaaaagaaa tatttattac cgaaaaaaag gggaaatcga gtcaagtacc
     2101 aacaggctca tctattccaa aaagatattt actcgatgga aaaactccta gaattagtgc
     2161 tacaaatatt gacaatggta tcttaggtta c
//
LOCUS       DAVLDI010000111         2143 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLDI010000111 DAVLDI010000000
VERSION     DAVLDI010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2143
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.112"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            129..1622
                     /locus_tag="VXD01_002221"
     CDS             129..1622
                     /locus_tag="VXD01_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV0602517.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1635..>2143
                     /locus_tag="VXD01_002222"
     CDS             1635..>2143
                     /locus_tag="VXD01_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV0602518.1"
                     /translation="MKKVKLGEVCEILSGYAFKSSQFNDNKIGLPLIRIRDVERGFSD
                     TYFEGTYPEEYLIKNGDLLITMDGSFILKKWEGDLALLNQRVCKIKITDKSVDEGYIS
                     WLIPKFLKEIEDKTPFVTVKHLSVAKIKDISFVLPNKLEQKLIAKKLNTISQIYDFRK
                     IQSEKFNELV"
BASE COUNT          750 a          315 c          419 g          659 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga ccagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
      661 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
      721 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
      781 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
      841 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
      901 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
      961 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
     1021 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
     1081 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
     1141 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
     1201 atgctgtaat ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt tcaactgcta
     1261 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
     1321 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
     1381 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
     1441 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
     1501 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaagtcata ttaaagaaaa
     1561 tcaatgattt agaaaaagaa attcaagctg gcttggctga attggaaaaa ttactcaagt
     1621 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt ttgtgagatt ttatctggtt
     1681 acgcttttaa atcatcacaa tttaatgata acaaaattgg tctcccctta atacgaattc
     1741 gagatgtaga aagaggtttt tctgatacct actttgaagg aacttatccc gaagaatatc
     1801 ttattaaaaa tggagactta ttgattacaa tggatggcag ttttatattg aaaaaatggg
     1861 agggggattt agcgctactt aatcaacgtg tctgtaaaat taaaattacg gataaaagtg
     1921 tagatgaagg ttatatatct tggttgattc ctaaattttt aaaagaaatt gaagataaga
     1981 ccccttttgt tacagtgaaa catctttcag tagctaaaat aaaagatatc tcatttgtat
     2041 tgcctaataa actagaacaa aagctaattg caaaaaaact aaatacgata agtcaaattt
     2101 atgattttcg taaaattcaa tcagaaaaat ttaacgagct cgt
//
LOCUS       DAVLDI010000112         1936 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLDI010000112 DAVLDI010000000
VERSION     DAVLDI010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1936
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.113"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..397
                     /locus_tag="VXD01_002223"
     CDS             <1..397
                     /locus_tag="VXD01_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV0602519.1"
                     /translation="PGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPMYTFKTMY
                     SYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAAKTIIEDK
                     SNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            419..874
                     /locus_tag="VXD01_002224"
     CDS             419..874
                     /locus_tag="VXD01_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HEV0602520.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            1379..1828
                     /locus_tag="VXD01_002225"
     CDS             1379..1828
                     /locus_tag="VXD01_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV0602521.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDISKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEETILYNFLSQMELSEYKVDDDWQ
                     QMNGEALFSIILKKNMLLLLEPNDAHKTGLLVEEPINIKKVVFKVKI"
BASE COUNT          717 a          214 c          333 g          672 t
ORIGIN      
        1 accaggtttt gaaaattctt ttatccttga tcagggaact agagctacta acagatcatg
       61 taggcacatt gataattcat ctatgatgga cgaaattctt gattttccaa tgtatacatt
      121 taagactatg tatagctatc aaactcctaa agaaataacg tataaatcaa ttgtaggtgg
      181 aaaattgaat aatttgtttg taataggtaa aggtgcttac caatccgaaa gttttagatc
      241 acaaattagt tgtatgttaa tggggatatc atcagcagca gcggcaaaaa ctattattga
      301 agataaaagc aatactctaa acattaatag agatttgttt aaatcgaact tagatatatt
      361 atttacatgg gagttttcta attggattac tgattaacaa ataataaggg aatattaaat
      421 gaatgatact aataaaaatc aatactttgt ttatgaattt gatactagct ttgtagaaat
      481 gtcttattct cagttttttg aaggatattg tattcttttt tcaaaagaac cctatccttc
      541 tttatctgat atgccaatgg aatttagaaa agaattttta atggaaatga gtatattagg
      601 tgatgcgatg cttgaagtgt taaatgccta tagaattaat tatgatatct taggaaattc
      661 aacacctgta cttcatgctc atttatttcc gagatacatg tgggaagagg aagagagaag
      721 aaaaactgta gttcatagat atgattcttc agtttttagc aatcctgagt ttgaatttac
      781 tatagaaaag catggaccaa ttattaaaaa actgaggtct gctattgata gacattatag
      841 agagtatcaa caattattag atgattcaaa ctgaactcca cattttcgat tagatttaat
      901 accttgtata ttacaactag gttgtggatg atataatttt ttgaaaaata tattttagga
      961 atgacttata aagcaattat atcagaggct attaaatcaa tggccaaagc ttatgctcct
     1021 tattcttatt ttaaggttgg agctgcgtta gaaactgaag ataaaaattt tttcctggat
     1081 gtaatataga aaatgttgct tttctcctac ttgctgtgca gaacgagtat atttttacaa
     1141 agctgtattt aaaggagaac gttcgttttc aaaaatatgt attgtaggcg gaaaaaaagg
     1201 tattttatca tcttttatag catcttgcag ggtgtcttgt caggtaatga tagaattttg
     1261 taatcttgat tcatttgtag ttatattggc tagtgatgtt gataattata aagtatataa
     1321 acttaaagaa ctactaccag ttagttttaa tcaagaaaat ttataacagg agggaactat
     1381 ggaattagtt gaatttaaaa atggacatgt taatacggtt catgagcata tcgcaataac
     1441 gaaagtaaaa gagtttctaa ataatcatga tatatcaaaa gataaaggtg gcatacataa
     1501 aatttctact gatttctttt acaatataat tgatatggaa actacaactg aagagaatag
     1561 accgtgggaa agtcataagg aatattatga tgtccattat ctgttaaatg gagaagaaac
     1621 aattttatat aatttcttgt ctcaaatgga attgtctgaa tataaagtag atgatgattg
     1681 gcaacaaatg aatggggaag ctttatttag tattatatta aagaaaaata tgttactttt
     1741 gttggaacca aacgatgcac ataaaacagg cctattggtt gaagaaccaa ttaatattaa
     1801 gaaagttgtt tttaaggtaa aaatttaact gaaagtactt tcagggatta agaattttaa
     1861 aatatttaag aaattgtatt ctaaagttct aaaattatag atatttaatt taaagcttgt
     1921 taaaatagaa tagtaa
//
LOCUS       DAVLDI010000113         1837 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLDI010000113 DAVLDI010000000
VERSION     DAVLDI010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1837
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.114"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            5..808
                     /locus_tag="VXD01_002226"
     CDS             5..808
                     /locus_tag="VXD01_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV0602522.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAGLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRPKKQLANDSGKKKFHVMKAQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILTDSGYQGLMKIYPQAQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKVENIFAKVETFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(1546..1806)
                     /locus_tag="VXD01_002227"
     CDS             complement(1546..1806)
                     /locus_tag="VXD01_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602523.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFLDG"
BASE COUNT          618 a          342 c          333 g          544 t
ORIGIN      
        1 ttctatgaat gatgaagcaa gtaaacaact aactgatgca cgatttaagc gtcttgttgg
       61 tgttcagcgt accacttttg aagagatgtt agctggatta aaaacagctt atcaacttaa
      121 acacgcaaaa ggtggacgaa aacctaaatt aagcctagaa gaccttctta tggccactct
      181 tcaatatgtg cgagaatatc gaacttatga acaaattgcg gctgattttg gtattcacga
      241 aagcaactta atccgtcgga gccaatgggt tgaagtaact cttgttcaaa gtggtgttac
      301 gatttcaaga actcctctca gctctgagga cacggtaatg attgatgcga cggaagtaaa
      361 aatcaatcgc cctaaaaaac aattagcgaa tgattctggt aaaaagaaat ttcacgttat
      421 gaaggctcaa gcgattgtca caagtcaagg gagaattgtt tctttggata tcactgtgaa
      481 ctattgtcat gatatgaagt tgttcaaaat gagtcgcaga aatatcggac aagctggtaa
      541 aatcttgact gacagtggtt atcaagggct catgaagata tatcctcaag cacaaactcc
      601 acgtaaatcc agcaaactca agccgctaac agctgaagat aaagcctgta accatgcgct
      661 atccaaggag agaagcaagg ttgagaacat ctttgccaaa gtagaaacgt ttaaaatgtt
      721 ttcaacaacc tatcgaaatc atcgtaaacg ctttggatta cgaatgaatt tgattgctgg
      781 tattatcaat catgaactag gattctagtt ttgcaggaag tctattatat atgcacagac
      841 atatgaaatc tttttgagac agcagttatg atatatttat ccattcacaa catcttctgt
      901 actaatacta caatattggt acattttgat tacacaatcg tttcaaaaaa tatgatggaa
      961 gcctgagtat tttatagtaa ttcccttcct atcaactaga tcaaccagtt gagtgttgaa
     1021 tgttgaaaca ccctagcctc agcaaaggac tatgatcagc atttcctagc caataggacg
     1081 ctccaaatca cctattctaa gtccatcact agcttggtca gtaagataca gactgcaagg
     1141 cgagactgat gtggttgatg agattttgga agagtattac aatcatagat tcaccagtag
     1201 acttgaccgc agatttaact atagtagatt gaaactagaa tagtacacct ctacttctaa
     1261 aacattgtta gaaatcgatt tgactgtcct gatcaatttg tcctgttctc gtttcatttt
     1321 actatactaa aaaaccacct gaaacaaatc aagtgactag aggataaaaa caaaaactgg
     1381 gcaaaaagtt ttgaaaagca aaaaacgcat aatatcaggt cttgaaaaac cttgatacta
     1441 tacgtttgat tgtgggaaga ttgacttcat tttctcctga aattgaagtt ttttctagtt
     1501 tccagatata gacgaattca atatagccat ctcgctacaa ttattttaac catcgagaaa
     1561 atttttcaga atttcaaaaa tttcattttg atccaatgaa atgtcattat tttgaagaat
     1621 agttgacttc acaggctcta attctatcac aaagcggtgc atgtctgctt ttaccgcact
     1681 acttgatgtt atagccgata acttttcatc tcctagcaag gaagctgtca aacgggtaag
     1741 gtcattcaaa tgctttttaa tggacttact taaaccttga gcacctgtgg cagagcgctc
     1801 cctcatatcc agccaagctt tagccttaaa aataatt
//
LOCUS       DAVLDI010000114         1767 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLDI010000114 DAVLDI010000000
VERSION     DAVLDI010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1767
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.115"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..308
                     /gene="lytA"
                     /locus_tag="VXD01_002228"
     CDS             <1..308
                     /gene="lytA"
                     /locus_tag="VXD01_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV0602524.1"
                     /translation="DRWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGW
                     VKYKDTWYYLDAKEGAMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(446..625)
                     /locus_tag="VXD01_002229"
     CDS             complement(446..625)
                     /locus_tag="VXD01_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602525.1"
                     /translation="MRKVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(767..916)
                     /locus_tag="VXD01_002230"
     CDS             complement(767..916)
                     /locus_tag="VXD01_002230"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602526.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            1197..1664
                     /locus_tag="VXD01_002231"
     CDS             1197..1664
                     /locus_tag="VXD01_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV0602527.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            1697..>1767
                     /gene="ffs"
                     /locus_tag="VXD01_002232"
     ncRNA           1697..>1767
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VXD01_002232"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
BASE COUNT          510 a          304 c          411 g          542 t
ORIGIN      
        1 cagaccgctg gaagaagcac acagacggta attggtacta ctttgaccaa tcaggcgaaa
       61 tggctacagg ctggaagaaa atcgctgaga agtggtacta ttttgatgta gaaggtgcca
      121 tgaagacagg ctgggtcaag tacaaggaca cttggtacta cttagacgct aaagaaggcg
      181 ccatggtatc aaatgccttt atccagtcag cggacggaac aggctggtac tacctcaaac
      241 cagacggaac actggcagac aagccagagt tcacagtaga gccagatggc ttgattacag
      301 ttaaataaat agaaaggaaa ctttctaaat tgttctttca ccgcaggctt aggcttgcgg
      361 ttttttattt gctctgattc tttaaaaaag cgttttcttg aagaatagag aggtgttttg
      421 tcaaaaataa aaacagtgac cgaaatcact gcttatcagt tgtagcaaat tcataaagtt
      481 tttctgctgt gagaagtgcc attttgtcca tgcttgtttt tccttttctg aggtcagaaa
      541 cagtagtcca tggaactcca gcaccttggg aaatagcaga tgtagacatc gaactgtcta
      601 acaattcttg aataactttt ctcatcttat ttgtcctttt tattttttag ataaatatat
      661 acattgattg caattataaa aatagctatt gcactaacca ttgcatttcc tctttccatt
      721 tgataaaata gaggtgtaag gggctttcgc cccaacctct tagcgtttac ctttttcttt
      781 gacgggattt cggtttacgc tttttgtttt gccttgcgac cgttattgcg gtcactagac
      841 ttgcgatagc agttaccgtt tcaggaatat tgtctattgc cttttcaagt aacctgagcc
      901 aatcttcttt gttcaacttc atcaccccct ttccttatct tgattatatt atatcacggt
      961 acaccgagaa agtcaagcgt tttgatgaag tttttttaat tttttcaaaa aaaaatagac
     1021 cttgtccaga ggtcggggag ttggaggggg caccctccaa aagcattgat ttaataagat
     1081 tttattttac ctttttcata ataatctccc tatagagtca ccgcattcgg tggcttcttt
     1141 tgtgttggga ttcatgatat aataataaaa tcgataagta ggaaaagaga aaagagatgt
     1201 attatacgct tgaagaaaaa gaagtcttta tgagggaggc tttgagagag gctgagattg
     1261 ctcttgaaca cgatgaaatt ccaattggtt gtgtgattgt caaagatggg gaaatcattg
     1321 gtcgtgggca taatgcgcgt gaggaattac agcgagcggt tatgcatgcg gaaattatgg
     1381 ctatagagga tgcgaacttg agtgaggaga gctggcgctt gctggattgc acactttttg
     1441 tgaccattga accttgtgtc atgtgtagtg gggcgattgg gcttgcccgc attccaaatg
     1501 tggtctatgg ggctaaaaac cagaaatttg gcgctgctgg gagtttgtac gatatcttga
     1561 cagatgagcg tctcaatcat cgtgtggagg ttgaaatagg aattttggaa gatgaatgcg
     1621 cagctatcat gcaggatttt tttagaaata gacggaaaaa ataattttgc ttttaaaatg
     1681 aataggaatg tgatataata aatagtggag caacagttct gcgtgaagcg ggtcagggga
     1741 ggaatccagc agccctaagc gatttga
//
LOCUS       DAVLDI010000115         1727 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLDI010000115 DAVLDI010000000
VERSION     DAVLDI010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1727
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.116"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..370
                     /locus_tag="VXD01_002233"
     CDS             <1..370
                     /locus_tag="VXD01_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEV0602528.1"
                     /translation="IEKIIKISNKGNVYRAIRKSDEQKVIIKQSRPFVNYDAEGEWTA
                     LDDIKNEAYMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNI
                     REKTLDNIVNIVSDIHKLGI"
     gene            complement(445..1705)
                     /locus_tag="VXD01_002234"
                     /pseudo
     CDS             complement(445..1705)
                     /locus_tag="VXD01_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          527 a          316 c          286 g          598 t
ORIGIN      
        1 aatagaaaaa attattaaga tatcaaataa aggaaatgtt tatcgggcaa ttagaaaatc
       61 ggacgagcaa aaagtaatca tcaagcagtc aagacctttt gtgaattatg atgccgaagg
      121 agaatggaca gcacttgatg atataaaaaa tgaggcttac atgctaaaaa aattagccga
      181 taaaagttat actactaatt taactgatga attttatatc gtggatgatt attttcttgt
      241 tcaggaacaa gttgacgggt taaactttga agaatttatt cgagaaacag aacactcctt
      301 aaatattaga gaaaaaacac tggataacat tgtgaatata gtaagcgaca tccataaact
      361 gggaatataa aattgtagat atagctccta caaattttat atataccaaa aatgtactgc
      421 cccccaaaaa gttagacaat taatttatcc gaaggattta gttctgtatt gcacaggact
      481 aagtcctttt agttttacct taattcgttt attgttgtag taatcaatat agtctacaat
      541 agcttgttcc aattgcttaa gcgactgaaa cgacttctca taaccgtaaa acatttccga
      601 tttcagaatc ccaaagaagg actccatcat accattgtct gggctattac ccttgcgtga
      661 catagatgct tgaactccct tactctctaa gaaccgatga taagaatcgt gttggtattg
      721 ccagccttgg tcactatgga gaatcgtatt ctcgtagtgc ttctctgtga atgcctgttc
      781 caacattgtt tgtacttgtt ctaagttggg tgaagttgaa agattatagg cgataatttc
      841 gctattaaag ccatctaaaa ctggtgataa gtaaagcttt tgagtacttg ctggaatggc
      901 aaattctgtc atatctgtgt agcactgttc cattgtttta gatccttcaa attggccttg
      961 aatgagattc tctgccttct taccaacgtc tcctttattt tcgtttctgt cgcattttag
     1021 cttgtaaatt gagtactttc atcaagcctt gaactctttt atgatttacc agataaccac
     1081 gatttcttag ttctaaataa atccgacgat aaccataatt tcccttgtgt tcgataaaga
     1141 tggattgaat ttcagcttta agctcttggt ccttatctgg tttatctagc tgtttcaagt
     1201 gatagtagta gatcgaacga gctagtttaa tggcttttag aagaagagct aacgaaaact
     1261 cagtcattaa ttcttgaaca atttctgtct ttcttctttc tctttttcct ccttcaatcg
     1321 gagttctctt aactttttta ggatggcatt ctccgctctc aggtactctc cctcttgttt
     1381 tctcaacaat agtatacccg tttttcctgt attgtgctag ccagttaaga agtatcgtac
     1441 gacttgggag accgtattca agagaaactc tatctttagt ccagccttca tgtaagactt
     1501 tattaatcat ttcttgtttt aaatcaggag aatagtaacg attttttcct tttttgacga
     1561 actctatgcc ataacggtca attaatttca ccatgtactt tagaccagaa acatccacac
     1621 caaatctttt tgaaagctgt ttgaagcttt gtccttgctt tcttagttca tagatctgaa
     1681 ctttatcttc ataacttaat ttcataataa aacaccccaa aagttag
//
LOCUS       DAVLDI010000116         1695 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLDI010000116 DAVLDI010000000
VERSION     DAVLDI010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1695
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.117"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..311
                     /locus_tag="VXD01_002235"
     CDS             <1..311
                     /locus_tag="VXD01_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602529.1"
                     /translation="QVKVVDKLTDSESKKYGEYIDLYESCRQNNLSVLLNFLQNSDDK
                     RGVIASNSVRIMFESLDKADQIAALNICRNYVARENVLNKEDAEKLLNEIDKKLEISR
                     "
     gene            367..1062
                     /locus_tag="VXD01_002236"
     CDS             367..1062
                     /locus_tag="VXD01_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0602530.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
                     NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            1074..1490
                     /locus_tag="VXD01_002237"
     CDS             1074..1490
                     /locus_tag="VXD01_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0602531.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEHALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPIYQRQGIGSALMKEALKDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
BASE COUNT          528 a          262 c          401 g          504 t
ORIGIN      
        1 cgcaggtaaa agttgtagat aaacttactg attctgaatc gaaaaaatac ggtgaatata
       61 ttgatttgta cgaatcgtgt cgtcagaaca atttaagtgt tctacttaac tttcttcaaa
      121 attcggatga taaacgagga gttattgcta gtaactcagt gagaattatg tttgaatctt
      181 tggataaagc agaccaaatt gcggccctga atatttgtag aaactatgta gcacgagaaa
      241 atgttttaaa taaagaagat gcagaaaaat tgttaaatga aattgataaa aaacttgaaa
      301 ttagcagata ggacaattca aatagagttg agtaaaaagt ttgaaaagtg aaacaaggag
      361 aaagctatgc cagtaaatga atatggtcag atgattggtg agtcaatgga aggttataca
      421 cccggtgcac tgccttctat tgatttctta gaagggcgtt atgctaggat agaggctctc
      481 tcggtagaaa aacatgcgga ggatttgcta gctgtttatg gcccggatac tcctcgggag
      541 atgtggacct atctttttca ggagccagta gcagatatgg gggagctggt tagcctttta
      601 aatcagatgt tggctcgtaa ggaccgtttt tactatgcaa tcatagacaa ggcgactggt
      661 aaggctttgg gaactttttc tctcatgcgc attgaccaga ataaccgagt aatagaagtc
      721 ggagcagtca ctttttctcc agagctaagg ggtacacgga taggaactga ggctcagtat
      781 ctcctagctc gctatatttt tgaggagcta aactatcgtc gctacgagtg gaaatgcgat
      841 gccttaaatc tgccatccag acgagttgcg gagcgtttgg gatttgtcta tgaaggaacc
      901 ttccgccagg cggtggttta taaggggcgt acgagagata cggattggtt gtctatgatt
      961 gatatggact ggcctcaagt caaagatcgt ttggaaacat ggctgcgtcc tgaaaatttt
     1021 gataaaaatg gacagcagta caagagcttg agagaacttt aagaggtgtt gagatgatta
     1081 ctattaaaaa gcaagaaatt gtcaagctag aggatgtttt gcatctctat caggctgtcg
     1141 gttggacaaa ttatacccat caaccagaga tgctggagca tgccttatcg cattcattag
     1201 taatttatct ggcacttgat ggtgatgctg tggtgggctt gattcgtttg gttggagatg
     1261 gattctcatc agtttttgta caggatttga ttgttttacc aatctatcag cgtcaaggga
     1321 ttggtagtgc cctaatgaaa gaggccttaa aagattacaa agatgcttat caagtccagc
     1381 tggtgacaga agagacagaa aaaaacgtgg gattttatcg ttctatgggc tttgaaatct
     1441 tatccaccta taattgtata gggatgactt gggcgaatcg agaaaaataa caaaacttgt
     1501 tttttcttaa gcaaaattta aggatggtct agtattatat agtcattaaa taaagacctc
     1561 ctaactttat ttaataaaat cctaaacttt tttcatcaca atctcctaat gaagccaccc
     1621 aatcaggtgg cttttttgcg tggtgaggtg ctggtgatag aaattttttg caaaatagta
     1681 aaattttaga aaagt
//
LOCUS       DAVLDI010000117         1691 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLDI010000117 DAVLDI010000000
VERSION     DAVLDI010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1691
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.118"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            18..1019
                     /locus_tag="VXD01_002238"
     CDS             18..1019
                     /locus_tag="VXD01_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV0602532.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT          562 a          229 c          342 g          558 t
ORIGIN      
        1 cgtaatggag gactgaaatg aaaaatataa atgggaaaaa ggtaactatt tatgatattg
       61 cacgtttatc aggtttttct ccaaaaacag tttcacgagt tattaatggt ggagtaaatg
      121 ttaaagaaga aacttatcaa gcgattcaaa aagttataga ggaattgtcg tatattccaa
      181 atgcgtatgc aaaaaattta actaaaaaag aagctataaa tatattgatt tctgtaaaaa
      241 aaatcgactc ttttccttta atttggtttc atacgctgtt agataaagtg ttacggacgt
      301 gtaaagaatt tggtgttaat gctatagttg agtactttgg agaggaggat acaattagta
      361 attcaattat atcaagcaca ggtagcctag tagatggtgt tattgttttt tatgaaagtg
      421 tagatgatat cagaattcag tatttaaaga agaaccatat gccttttctt gttttcggtg
      481 aatctcaaac gtctggagta gtctatgtat ctaataataa ttttcaagct acttatgata
      541 tgatgaaagc tgtaactgaa gaaaaattta aaaatatgtg gttgcttatg ggaggagaat
      601 cccatgttaa taaggatcgt gaaagaggtg tgcgttcttt tctgaatgat aaaaattact
      661 ttatggattt aaaagtcatt tatggcttat ctacaattga ttcagtttat tcttatgcaa
      721 tgcagcactt gactacccaa aattatccgg acattatttt tgtttcagga gatgaaaagg
      781 ttcagggctt gattcgtgcg tgctatgaga aaggaattct tattccagat gatatttcta
      841 tcattggatt tgataatatt cctatttctc agtattatac tccagctttg tctacaattg
      901 ctcccaatta tgttaaattg gctaaagaaa tgatagaagg tgttttagca attattaaag
      961 gggaaagtgt cacatctgtt gaagtttctc ctaaatttgt taggagacag agtttctagt
     1021 attgtttaat tcttgaaaat cctagtggaa aagatggagt gttctaaaat aagttctgtt
     1081 tagcctccat tcagtttcta ttgagttgga tccaatttct aacgagtggg acatgttcat
     1141 gttcgatcta aggaagacat ggtcacattc gaatgatatt ttcaaaaaaa tcgtaaaaaa
     1201 gtcttgacaa agaaaaaaca aagtattaaa ataagttcaa caaatcagaa aagtaactat
     1261 ttttgatctt cagggagcct gtggtgattg tgaataggtg gttggaagta gtgaaagtgg
     1321 gctgattttg aaaatgaatt tgaaacaatg aaaattcggt gcgcacacct tacagtgcag
     1381 cttgttgtta aacaaggcag agatgtaaag ggatagtccc tttataattg aggtggcatc
     1441 gcgttaccaa cgccctcaca cggaagtata ttctgtgtgt gggctttttt ctatccgtcg
     1501 tttggtttat cttttattag ggccttaagt cgctttgatg aacttgagtt ctatctacag
     1561 ctccttgcct actactaaaa gcaaacaaaa aggctggact aatacgaaaa aagctagtaa
     1621 tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgctc aaaacactgt
     1681 tttgaggttg t
//
LOCUS       DAVLDI010000118         1673 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVLDI010000118 DAVLDI010000000
VERSION     DAVLDI010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1673
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.119"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            285..1631
                     /gene="gdhA"
                     /locus_tag="VXD01_002239"
     CDS             285..1631
                     /gene="gdhA"
                     /locus_tag="VXD01_002239"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV0602533.1"
                     /translation="MTSAKEYIQSVFETVKTRNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          516 a          319 c          337 g          501 t
ORIGIN      
        1 aaaatggtca tagttttact ggcaaatcta acatatcacg gataaattaa caagtgattt
       61 ctgaattgct aaacattttc ttttcttata gcataccata ctttaagatt ttgtctttga
      121 gaaagatatt tccaagaaaa acgttcgttt ttttatctat tttcaaaaaa cccaaaaact
      181 gaattgaaag aatttttaga aaatttctgt tttttcttta cagtgaaaaa aaattctgct
      241 ataatgtctt atgtaataaa atatgacaat aaaaggagaa cgatatgaca tctgctaaag
      301 aatatatcca aagcgtgttc gaaactgtaa aaactcgtaa cgggcacgag gctgaattcc
      361 tccaagctgt tgaagaattt ttcaacactt tggaacctgt atttgaaaaa caccctgagt
      421 atatcgaaga aaatatcttg gcacgtatta ctgagcctga gcgcgtggtt tctttccgtg
      481 ttccttgggt tgaccgtgat ggaaaaattc aagtaaaccg tggttaccgt gttcaattca
      541 actcagctgt tggaccatac aaaggtggac ttcgtttcca cccaactgta aaccaaggga
      601 tcttgaaatt cctcggattt gaacaaatct ttaaaaatgt cttaactgga cttcctatcg
      661 gtggaggtaa aggtggatca gacttcgatc ctaaaggtaa aacagatgct gaagtgatgc
      721 gcttctgcca aagcttcatg actgaattgc aaaaacacat cggaccatca cttgacgtac
      781 ctgctggtga tatcggtgtt ggtggacgtg agattggtta cctttacggt caatacaaac
      841 gtcttaacca atttgatgct ggtgtcttga ctggtaaacc tcttggattt ggtggtagct
      901 tgattcgtcc agaagcaact ggttacggtt tggtttacta tactgaagaa atgctcaaag
      961 ctaacggtaa cagctttgct ggtaagaaag tcgttatttc aggttctggt aacgttgctc
     1021 aatatgctct tcaaaaagca actgaactcg gtgcaactgt tatttctgtt tctgactcaa
     1081 atggttatgt catcgatgaa aatggtatcg acttcgatct tttggttgat gttaaagaaa
     1141 aacgtcgtgc tcgtttgact gagtatgcag ctgaaaaagc aactgcaacc taccacgaag
     1201 gtactgtatg gacttacgct ggaaactatg acattgctct tccatgtgcc actcaaaacg
     1261 aaatcaacgg tgaagcagct aaacgtttgg ttgctcaagg cgttatctgt gtatctgaag
     1321 gtgccaacat gccgagcgac cttgatgcca tcaaagttta caaagaaaat ggtatcttat
     1381 acggacctgc aaaagctgcc aacgctggtg gtgtagccgt ttcagctctt gaaatgagcc
     1441 aaaacagtct tcgcctctca tggactcgtg aagaagttga tgaccgtctc aaagacatca
     1501 tgacaaacat cttcaacaca gctaaaacaa cttcagaaac atacggtctt gataaagact
     1561 accttgcagg agctaacatt gctgcctttg aaaatgtagc aaatgccatg attgcacaag
     1621 gtattgttta agatttattt actcaatcct caatcactac gattggggat ttt
//
LOCUS       DAVLDI010000119         1554 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVLDI010000119 DAVLDI010000000
VERSION     DAVLDI010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1554
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.120"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..921
                     /locus_tag="VXD01_002240"
     CDS             <1..921
                     /locus_tag="VXD01_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0602534.1"
                     /translation="KTANFEAGSVTTTILDAEAVTAEKLKVDNALIRKLTANDAFIDQ
                     LISKRIFSTKVESVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGA
                     GYGVRTAFWANWGNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNT
                     TFSRSPVFSNGIELGSKDVLGDGWNPKGGRNAVVWWNQVGSGSLKYWMEQKSDRRLKE
                     NITDTAVKALDKINRLRMVAFDFIENKKHEEIGLIAQEAETIVPRIVSRDPENPDGYL
                     HIDYTALVPYLIKAIQELNQKIEKMEKTIA"
     gene            918..1034
                     /locus_tag="VXD01_002241"
                     /pseudo
     CDS             918..1034
                     /locus_tag="VXD01_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
     gene            1015..1218
                     /locus_tag="VXD01_002242"
     CDS             1015..1218
                     /locus_tag="VXD01_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602535.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            1221..>1554
                     /locus_tag="VXD01_002243"
     CDS             1221..>1554
                     /locus_tag="VXD01_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602536.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWALNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPT"
BASE COUNT          518 a          278 c          356 g          402 t
ORIGIN      
        1 aaaacggcca attttgaagc tggttcggtc acgactacga tattagacgc tgaagcggta
       61 actgctgaga agttgaaagt tgacaatgcg cttattagaa aattaactgc aaatgatgct
      121 tttattgacc aactgatatc taaacgtatc ttctctacta aggttgagtc cgtcatttct
      181 agctcaacct tcctagaagc ctatcaaggc cgaatcggtg gattcacact tggtcaattt
      241 gaccagggtg gcggtcgctg gatttcaggt gtcaatcagt tctctgttgg tatggggaat
      301 ggtgccggat atggagtccg gacagccttc tgggcgaact ggggaaataa ttggaactat
      361 gccggaccta aagcatggaa cgtcaatact gatgggaaaa tgtactgtag gaatgaagtc
      421 ggtttttatg atcaagtgga tttttcgaat tcatcgagag caaacttcta tgggaatact
      481 actttttctc gttctcctgt gttttcaaat ggtatcgaac ttggaagtaa agatgtgctt
      541 ggtgatggtt ggaatcccaa aggcggaagg aatgcggttg tttggtggaa tcaggtcggt
      601 agcggtagct tgaagtattg gatggaacaa aaatcagaca gacgcttaaa agagaacatc
      661 acagatacag ctgtgaaagc cttggataaa atcaacagat taagaatggt tgcatttgat
      721 ttcatcgaaa ataagaaaca tgaggagatt ggtctaatag ctcaagaggc tgaaaccatc
      781 gttccaagaa ttgtctcacg agatcctgag aatccagatg gctatctgca tatcgactat
      841 accgctttag ttccttactt aatcaaggct attcaagaat taaatcaaaa aatagaaaaa
      901 atggagaaaa caatagcatg aataacaaca tgttgaccaa tatcgcactt aaagcaattt
      961 aggagcttgc tcttgaaaat agaaaacgaa cacacagatt ggagaactta gaaaatgaac
     1021 acagaacagc ttaaccaagc cttacaaatg acaattcgtg aaatgtcaac aacttcaaca
     1081 gattcgatga ttacaagtaa tatcttgagt attcagttga atgagcaaag ggaagagaat
     1141 caaagacttc aagcacgagt ggatgagctg gaagctctgc ttgatgaaca aactaaacca
     1201 gcagacaaag gagaatagac atggcagaaa caattcaaaa cacagataac ttactagacc
     1261 ttacaaaaat cacagaacca tttgatcttg cgagcgcttt gcgctacatg aaagaaaatg
     1321 gagaattcat tcgttgcaag aatgtaagcg atgacttcta tatgtatcgt gatgttcaaa
     1381 aacgtcctgt gatcgtaaat ggccgtcgcc aattcaagga tgttgaaacc gtttgggcgc
     1441 tcaaccagtg gggtggtaca atcgcaacaa tcaacgtagc cgttctgttg aatcatgaat
     1501 tctatatcat gaaatttgat gcagagggca atcctgactg gacggttcca acgg
//
LOCUS       DAVLDI010000120         1549 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVLDI010000120 DAVLDI010000000
VERSION     DAVLDI010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1549
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.121"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..915
                     /locus_tag="VXD01_002244"
     CDS             <1..915
                     /locus_tag="VXD01_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0602537.1"
                     /translation="KTGNFEAGSVTTTILDAEAVTAEKLKVDDALIRKLTANDAFIDR
                     LTSKRIFSTKVESVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGA
                     GYGVRTAFWANWGNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNT
                     TFSRSPVFSNGIELGSKDVLGDGWNPKGGRNAVVWWNQVGSVKYWMEQKSDRRLKENI
                     TDTAVKALDKINRLRMVAFDFIENKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLHI
                     DYTALVPYLIKAIQELNQKIEKMEKTIA"
     gene            1010..1213
                     /locus_tag="VXD01_002245"
     CDS             1010..1213
                     /locus_tag="VXD01_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602538.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMIASNFLSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            1216..>1549
                     /locus_tag="VXD01_002246"
     CDS             1216..>1549
                     /locus_tag="VXD01_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602539.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPT"
BASE COUNT          513 a          274 c          359 g          403 t
ORIGIN      
        1 aaaacgggca attttgaagc tggttcggtc acgactacga tattagacgc tgaagcggta
       61 actgctgaga agttgaaagt tgacgatgcg cttattagaa aattaactgc aaatgatgct
      121 tttattgacc gactgacatc taaacgtatc ttctctacta aggttgagtc cgtcatttct
      181 agttcaacct tcctagaagc ctatcaaggt cgaattggtg gattcacact tggtcaattt
      241 gaccagggtg gcggtcgctg gatttcaggt gtcaatcagt tctctgttgg tatggggaat
      301 ggtgccgggt atggagtccg gacagccttc tgggcgaact ggggaaataa ttggaactat
      361 gccggaccta aagcatggaa cgtcaatact gatgggaaaa tgtactgtag gaatgaagtc
      421 ggtttttatg atcaagtgga tttttcgaat tcatcgagag caaacttcta tgggaatact
      481 actttttctc gttctcctgt gttttcaaat ggtatcgaac ttggaagtaa agatgtgctt
      541 ggtgatggtt ggaatcccaa aggcggaagg aatgcggttg tttggtggaa tcaggtcggt
      601 agcgtgaagt attggatgga acaaaaatca gacagacgct taaaagagaa catcacagat
      661 acagctgtga aagccttgga caaaatcaac agattaagaa tggttgcatt tgatttcatc
      721 gaaaataaga aacatgagga gattggtcta atagctcaag aggctgaaac catcgttcca
      781 agaattgtct cacgagatcc tgagaatcca gatggctatc tgcatattga ctataccgct
      841 ttagttcctt acttaatcaa ggctattcaa gaattaaatc aaaaaataga aaaaatggag
      901 aaaacaatag catgaataac aacatgttga ccaatatcgc actttaaagc aattcaggag
      961 cttgctcttg aaaatagaaa acgaacacac agattggaga acttagaaaa tgaacacaga
     1021 acagcttaac caagccttac aaatgacaat tcgtgaaatg tcaacaactt caacagattc
     1081 gatgattgca agtaatttct tgagtattca gttaaatgag caaagggaag agaatcaaag
     1141 acttcaagca cgagtggatg agctggaagc tctgcttgat gaacaaacta aaccagcaga
     1201 caaaggagaa tagacatggc agaaacaatt caaaacacag ataacttact agaccttaca
     1261 aaaatcacag aaccatttga tcttgcgagt gctttgcgct acatgaaaga aaatggagag
     1321 ttcattcgtt gcaagaatgt aagcgatgac ttctatatgt atcgtgatgt tcaaaaacgt
     1381 cctgtgatcg taaatggccg tcgccaactc aaggatgttg aaaccgtttg ggcgttcaac
     1441 cagtggggtg gtacaatcgc aacaatcaac gtagccgttc tgttgaatca tgaattctat
     1501 atcatgaaat ttgatgcaga gggcaatcct gactggacgg atccaacgg
//
LOCUS       DAVLDI010000121         1477 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVLDI010000121 DAVLDI010000000
VERSION     DAVLDI010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1477
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.122"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            29..769
                     /locus_tag="VXD01_002247"
     CDS             29..769
                     /locus_tag="VXD01_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602540.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            772..>1477
                     /locus_tag="VXD01_002248"
     CDS             772..>1477
                     /locus_tag="VXD01_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV0602541.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIV"
BASE COUNT          481 a          191 c          294 g          511 t
ORIGIN      
        1 tcaaaattaa gtgattggag gcaagaatat ggataaagat tatatattaa aagtgaaagg
       61 gctgtatcat caatttttac taggaaataa taaaacgttg caagtgctga aaaatgtttc
      121 tctttctgct tcgagaggag aatttataag tattctagga attagtggtt ctggaaagtc
      181 aactttatta aaatgtattt ctagtttgct tgaaccaaca agtggggaag taattttaaa
      241 tggaatcaac ccctataaaa tcagaaatgc aaaattgtca agtataagac gtaacgaagt
      301 atcttttata tttcaagcat acaatttaat accttccctg ccggtaatag aaaatatagc
      361 acttcctttg cgattatcac aaaaaaaatt aactattaaa aatgtagaaa acttactcaa
      421 aagaatgaag tttaatgctg gcttaaacga ttttgttgga actctgtctg gtggagaaca
      481 acagaaggtt gctatagcta gagcggttat tgctgatagt gatataatat ttgctgatga
      541 gccaactggg gctttagaca gcgtttctcg tgaagtaatt tttgaattat tgagagagtt
      601 agtaggggcg ggtaagtgtg taattatggt aacgcacgat atagaattgg cctcgaaaac
      661 tgatcgtgca ttaatattga aagatggaaa aattttcaaa gaacttcata gacctagcgg
      721 ggaagagttg tataaaatct tagaggtaca atcaactacg gaggaataga gatgctcaga
      781 ttagtttact atcaattttt acataataag aaacaatggt taggcgtttc accagtaatt
      841 tttgtttcga gtttagttat gggattggct gttaatgggg taattaatgt tgagaataat
      901 tcgcaagtat ttgtcggact tccagatcct aaaccaattt ttatgtttcc gatagtattc
      961 ggaggagtaa cattattctt tgtgctctct aacataataa atatgttggt tgaaattttt
     1021 agagatgatt acgaacttct ggaggtgttg ggagcaagtc gccttcaact atcatttctt
     1081 gtggggggac agatttttat catttcctcg attattagtt ttattgcata tctatgctct
     1141 atatttgtta cgtcaaatta ttattatttt ttacaatact ttttcgggga aaatatatta
     1201 cctgatatcc aatttcaaac gagtgctgtt ggatgtatca ttacagtagt gttgatttca
     1261 tttttagcct ttctaagtgg ttgcttttat acgttcaaga agattagaaa taggaagagt
     1321 tctaaaataa ggcatgttct ttcaatagta aaaagaatac tgctattggc tggttttagt
     1381 gttatctggt tgctttcttt gcaacaaatt ttccaagata gcacaatttt agcgaaggcc
     1441 cagataatat tcaatattgt aatcttagat attgtga
//
LOCUS       DAVLDI010000122         1317 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVLDI010000122 DAVLDI010000000
VERSION     DAVLDI010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1317
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.123"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            181..942
                     /locus_tag="VXD01_002249"
     CDS             181..942
                     /locus_tag="VXD01_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV0602542.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(1226..>1317)
                     /locus_tag="VXD01_002250"
     CDS             complement(1226..>1317)
                     /locus_tag="VXD01_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3884 domain-containing protein"
                     /protein_id="HEV0602543.1"
                     /translation="EELKSLFLNFINPEEWDTISFDSDFMPFQ"
BASE COUNT          469 a          210 c          220 g          418 t
ORIGIN      
        1 tctccaccac tcttaaccat caaaaagtaa actagaaaca acaaaataat aacttaataa
       61 aaatatcgaa agttttgaaa ataaacttcg atatttttgt ttttgtttta ttttgttgtt
      121 tttgtatttg aatgatgagc tagtttatgg taagatagta gtaggaaacg aggtgataat
      181 atgctcaaac aagaaaaatt aaccaaaatt ttagagatag taaatagtaa aggaaccata
      241 acagttaaac agattatgga cgaaatagcc gtttcagata tgactgcaag gcgctattta
      301 caggaattag ctgataaaga tttgctgatt cgtgtgcatg gtggagctga aaaacttcga
      361 accaactccc ttttgactaa tgagcgatca aatattgaaa aacaagccct ccaaacggca
      421 gaaaaacaag aaatagccca ttttgcaggc agtctagtag aagaaagaga aactattttc
      481 attggaccag gaacaacatt agagtttttt gcgcgtgagt tgcctattga caatatccgc
      541 gtcgtaacca acagtctacc tgtttttctg attttaagcg aacgaaaatt aacagatttg
      601 attttgatag gtggaaatta tcgcgatatt acaggtgctt ttgttggcac attgacccta
      661 caaaatctct ctaatctcca attttctaaa gctttcgtta gctgtaatgg tattcaaaac
      721 ggagctctag ctacttttag cgaggaagag ggagaggctc aacgcatcgc tttaaataat
      781 tctaataaaa aatatttact cgcagatcat agtaagttca ataagtttga tttttatact
      841 ttttataatg tatcaaatct tgatactatt gtttcagatt ctaaactaag tgattcaatc
      901 ctttttaagc tatctaaaca cattaaagtc atcaagcctt aataaactga aagagcctgg
      961 gtaacaactc aatttcagaa gaaaaaaagt aaatcttccc acaataaaaa gcatagtatc
     1021 aggtgttgaa acacctgata ctatgctttt tctatatcaa agactttttg cccaattcct
     1081 caaagctatg cattgagaaa tctgcgactc gcttcctagt ttaaagttgc tctttgattt
     1141 tcattgagta taagcaacgt gattagataa gagttttgca gagtactaaa tataagattt
     1201 aacttttttg agaaattggt tacgattatt gaaacggcat aaaatctgaa tcaaaggaga
     1261 tagtatccca ttcttcagga ttgataaaat ttaaaaatag acttttcaat tcttcac
//
LOCUS       DAVLDI010000123         1212 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVLDI010000123 DAVLDI010000000
VERSION     DAVLDI010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1212
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.124"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..578
                     /locus_tag="VXD01_002251"
     CDS             <1..578
                     /locus_tag="VXD01_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV0602544.1"
                     /translation="SKIPSGLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLL
                     NRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRI
                     ALARALINNPSIVILDEATSALDTINEERITKYIKSQGCTQIIVAHRLSTIKDADIIV
                     VMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
     gene            591..761
                     /locus_tag="VXD01_002252"
     CDS             591..761
                     /locus_tag="VXD01_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602545.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
BASE COUNT          447 a          146 c          221 g          398 t
ORIGIN      
        1 tatcaaaaat accatcagga ttatataaga ttgatacagg aaaagtttta tttgatggtg
       61 taaatattaa tcaaatagat aaaaaaatat taagtcaaaa tttaggagta gttccacagg
      121 attcgttttt attgaacaga agtattcttg ataacataac tttaaagcac gaagttactt
      181 cacaaaagat agaggaagtt tgtaaagcag ttcaaatcta tgatgaaatc atggctatgc
      241 cgatgaaatt taatactatc atctcagaga tgggttcaaa tatttcaggt ggtcaaagac
      301 aacggatagc actggcacgt gcattaataa ataatcctag tattgtaatt ttagatgaag
      361 caactagtgc tttagacact attaatgagg aaagaataac aaagtatata aaaagtcagg
      421 gctgtactca aataattgta gctcatagat tgtcaacgat taaggatgcg gatattattg
      481 ttgtaatgaa aggtggtaag attgttgagt caggaaatca taagtactta atggatcttg
      541 gtggagagta ctacagctta tatacaaaaa ggaaatgagg tgtaaagaaa atgaagaaag
      601 aaaatgaata tgtaatttta acaacagcct cactaggggt gatgattgga atagtgtttg
      661 caattttttt agattttcca gttgaatatg gtatttcttt aggcttattg aatggaatag
      721 tattgggttc gctgattgtt tacaaaaaca ataagaatta agcataattt tttgctgtaa
      781 actaaggagt agagatggct atagttgaaa ttataaatct aacaaaaagc tttaaagata
      841 ttgaagttat tcataacact taaataatag agcaactaca gtagtagctt aaaaacatga
      901 ttaaatcgct attcttagga gtagcggttt ttctttttgt ttaatactct ttgaaaatct
      961 cttcaaacca cgtcagcttt gccttgccgt actcaagtac agcctgcgac tcgcttccta
     1021 gtttgctttt tgattttcat tgagtataaa aagggttaag taagtatagt aaattgaaat
     1081 aagatatgaa caaatcgatt agaaaagtca aattaatttc tagaaatatg ttagaaattg
     1141 gtttgaattc cgcaatcaat ttgttcagtt tttatttcat ttaattagaa tttcccaact
     1201 gtctaactca ac
//
LOCUS       DAVLDI010000124         1190 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVLDI010000124 DAVLDI010000000
VERSION     DAVLDI010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1190
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.125"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            59..1084
                     /locus_tag="VXD01_002253"
     CDS             59..1084
                     /locus_tag="VXD01_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV0602546.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGLSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIRIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1074..>1190
                     /locus_tag="VXD01_002254"
     CDS             1074..>1190
                     /locus_tag="VXD01_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0602547.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDF"
BASE COUNT          464 a          162 c          198 g          366 t
ORIGIN      
        1 attgacaatg ataattatta tcgatataat agacttgaaa tatgttcaag gagtttttat
       61 gaaaaacaaa ttttttctaa tagctatttt agctatgtgt atagttttta gcgcttgttc
      121 ttctaattct gttaaaaatg aagaaaatac ttctaaagag catgcgcctg ataaaatagt
      181 tttagatcat gctttcggtc aaactatatt agataaaaaa cctgaaagag ttgcaactat
      241 tgcttgggga aatcatgatg tagcattagc tttaggaata gttcctgttg gactttcaaa
      301 agcaaattac ggtgtaagtg ctgataaagg agttttacca tggacagaag aaaaaatcaa
      361 agaactaaat ggtaaagcta acctatttga cgatttggat ggacttaact ttgaagcaat
      421 atcaaattct aaaccagatg ttatcttagc aggttattct ggtataacta aagaagatta
      481 tgacactcta tcaaaaattg ctcctgtagc agcatacaaa tctaaacctt ggcaaacttt
      541 atggagagat atgattagaa ttgattcaaa agccttaggt atggaaaaag aaggtgatga
      601 gttaatcaaa aatactgaag ctcgtatatc caaagaatta gaaaaacatc cagaaatcaa
      661 aggaaaaatc aaaggaaaaa aagtattatt tactatgatt aatgctgcag atacatcaaa
      721 attctggatt tatactagca aagatccaag agcaaattat ttaacagatt taggtctagt
      781 tttccctgaa tcattaaaag aatttgagag tgaagatagt tttgcaaagg aaatttctgc
      841 agaagaagca aataagataa atgatgctga tgtaatcata acttatggtg atgataaaac
      901 tcttgaagct ttacaaaaag atcctctttt aggtaaaata aatgcaatta aaaatggtgc
      961 cgttgctgta attccagata atacaccgtt agcagcctca tgcactccaa caccactttc
     1021 aataaactat actattgaag aatatctaaa tcttttagga aatgcatgca aaaatgcgaa
     1081 ataaaaaaca aataaaccta ggcataattt ttgtaatctg cctaggtctt cttattacaa
     1141 tatttttgtc attaaagctt ggaacaaaag aaattaatat cagagatttt
//
LOCUS       DAVLDI010000125         1153 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVLDI010000125 DAVLDI010000000
VERSION     DAVLDI010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1153
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.126"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            68..418
                     /locus_tag="VXD01_002255"
     CDS             68..418
                     /locus_tag="VXD01_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV0602548.1"
                     /translation="MLRHPCISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWTYLCSQVN
                     QNLEKIRQREGDTH"
     gene            633..749
                     /locus_tag="VXD01_002256"
     CDS             633..749
                     /locus_tag="VXD01_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV0602549.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            742..975
                     /locus_tag="VXD01_002257"
     CDS             742..975
                     /locus_tag="VXD01_002257"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602550.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGREERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT          376 a          221 c          244 g          312 t
ORIGIN      
        1 aatttgactt ttctgataga gttgttcaca tcttatttca actcactata gaaggaggaa
       61 aaggaggatt ctcagacatc cgtgcatcag cccaactaat gatttgattg ctaagaaaat
      121 attcagcaat ccagaaatca cttgtcaatt tattcgcgat atgctggact tgccagcaaa
      181 aaatgtgacc attttggagg gaagcgatat tcacgtatta ctctccatgc cttactcggt
      241 gcaggatttt tataccagta tagacgtctt ggcggagttg gataacggta ctcaagtaat
      301 tattgagatt caagtccatc atcagaattt tttcatcaat cacttgtgga cttacctgtg
      361 cagtcaggtt aatcaaaatc ttgaaaaaat tcgtcagcga gaaggtgata ctcactagag
      421 ctacaaacac atcgctcctg tttacgccat tgctatcgtg gatagtaatt atttctcaga
      481 tgacctggct tttcatagct ttagtatgcg cgaagacaca acaggtgagg tattggcgat
      541 taccaacaat ggacaggaaa accatctggt taagatggca ttcttggaat taaaaaatac
      601 agagaaacca gcaaagacaa ggttcgcaag ccatggttgg agtttttcgg caacaagccc
      661 tttacccagc aaccgcaacg agccattacc caagcaaatc aactgctgga ctacaagagc
      721 tggtccgagg aggacaggaa aatgtttagt caactacata tgcgagaaga acaagtcttg
      781 ttagcacagg actatgcctt ggaaactgct agggctgaag gccttgaaca aggactagag
      841 cgtgggaaag ttgaaggaag ggaagaaagg aaactttttg ccttcctaga catagtacgc
      901 caaggtcttc tgacttctga ggttgccagc cagcaattag gtatgtcagt atctgaattt
      961 gaggcactgt tgtaaaatgg ctctataata tttgtagtgt gtaaatcccc tatggatatt
     1021 atggagccta ttttgtgtag aaaaaaagtc ccatatgacc tataatgaaa agcgacaaaa
     1081 caactcatta gaaagaatca tatggaacaa ttacatttta tcacaaaatt actagacatt
     1141 aaagacccta atg
//
LOCUS       DAVLDI010000126         1073 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVLDI010000126 DAVLDI010000000
VERSION     DAVLDI010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.127"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..350
                     /locus_tag="VXD01_002258"
     CDS             <1..350
                     /locus_tag="VXD01_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HEV0602551.1"
                     /translation="DFEHALRKETQIEEKKLPLFGTPGFYETNLNLLNNQPEDIMGLV
                     LLLYWSQNLDDFNVFSKMSFLEAMEYAMNFNSRRLDTLDKSDWLYDIYKKAFNYKYDT
                     FSELKKDFIEVLK"
     gene            364..>1073
                     /locus_tag="VXD01_002259"
     CDS             364..>1073
                     /locus_tag="VXD01_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV0602552.1"
                     /translation="MNCFLKMNNVSVRYDDVIALKDITLQINKGDFIGLLGSNGAGKS
                     TLINSIVGFQEIYLGEIEYCDKDLIVSSQPFAHLGFTPQTTVIDFYTTVKDNVILGLN
                     LAGKFGKNAEKLCQIALEIVGLADKKNNLVETLSGGQLQRVQIARAIAHNPDFYILDE
                     PTVGLDTESAEKFLMYLKDKSLEGKTIIISSHDINLLEKFCKKILFLQNGSISFFGDM
                     RDFVDNSTIKLNFSMQNR"
BASE COUNT          378 a          123 c          198 g          374 t
ORIGIN      
        1 tagactttga gcatgcccta aggaaagaaa ctcaaattga agaaaaaaag ttgcctctat
       61 ttggaactcc agggttttat gaaaccaact taaatttatt gaataatcaa ccagaggata
      121 ttatgggatt ggttttgtta ttatattgga gtcagaattt agatgatttt aacgtctttt
      181 caaaaatgag ttttttagaa gcgatggagt atgcaatgaa ttttaattcg cgtcgcttag
      241 acacacttga taaatcagat tggctttatg atatttataa aaaagcgttc aattataaat
      301 atgatacttt ttctgaatta aaaaaagatt ttatagaggt attaaaataa aggtaggggt
      361 gttatgaatt gtttcttgaa aatgaataat gtaagtgttc gttatgatga cgtaatagct
      421 ttaaaagata taactttaca aataaataag ggagatttca ttggcttatt aggttcaaat
      481 ggtgcaggta aatctacgtt aattaattct attgtaggtt ttcaagagat ttatttagga
      541 gaaatagagt attgtgataa agatttgata gttagttctc aaccttttgc tcatttaggc
      601 tttactcctc aaaccacagt aattgatttt tatactactg tgaaggacaa tgtaatattg
      661 gggctgaacc ttgctggaaa gtttgggaaa aatgctgaga agttgtgtca aatagcctta
      721 gaaattgttg ggttagctga taaaaaaaat aatttggtag aaacattgtc aggtggacaa
      781 ctgcaacgcg tccagattgc tagagcaata gctcataatc cagattttta tattttagat
      841 gaacctaccg ttggtttaga tactgaatct gccgaaaaat ttttaatgta tttaaaagat
      901 aagagtttgg aaggaaaaac tattatcata tcttcacatg acataaatct actcgaaaag
      961 ttttgtaaaa aaatactttt tttacaaaat ggctccatat cattttttgg tgatatgcgt
     1021 gactttgtag ataattcaac tatcaaatta aatttttcaa tgcagaatag aat
//
LOCUS       DAVLDI010000127          991 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVLDI010000127 DAVLDI010000000
VERSION     DAVLDI010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.128"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..>991)
                     /locus_tag="VXD01_002260"
     CDS             complement(<1..>991)
                     /locus_tag="VXD01_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0602553.1"
                     /translation="TEAKATFERTAQGLRTDLSAIQEYVNKDGQRQEALQRYTREEST
                     RQATAVRELVNRDFVGKATYQEDVKGINQRIEAVKTSANKDIASQIASYRQSVDGKFT
                     DISSQITTYKQDVGGQISGLSNRLTSSEQGTTTQISNLSNRINSNKQGADNQISNLKT
                     QVATNKDNAERQMGRISDQVSANKANADSQFANVTNQLARKVETTDFQRVKETSKLYE
                     RILGNTENGIADKVARMALTNQLFQVEVGKYSVSGPNLIKNSDFKNSTNEWGSTQNLG
                     RLVKHSFYHNGQKDLMRLSNATKNENFLYSHRFNLERNTDYVLNFRGFNNSALA"
BASE COUNT          252 a          224 c          176 g          339 t
ORIGIN      
        1 ttgctagagc actgttgtta aatcctctaa aattcagtac atagtcagta tttcgttcaa
       61 gattaaaacg gtgactatac aaaaaatttt cgtttttagt tgcattactt aaacgcataa
      121 ggtctttctg cccgttgtga taaaagctat gcttaaccaa tcttcctaaa ttttgagttg
      181 agccccattc attcgtagaa tttttaaaat cactattctt aatgaggtta gggccgctta
      241 cactatattt cccaacctca acctgaaaca gttgattggt cagagccatg cgagcaacct
      301 tatccgcaat tccattttca gtattgccca aaatccgctc gtaaagttta ctggtttcct
      361 taacacgctg aaagtcagta gtctctactt ttcgcgctag ttgattggtc acattcgcaa
      421 attgactatc agcattcgct ttgtttgccg aaacctgatc agatattcta cccatttgtc
      481 gttcagcatt atccttgttt gtagcgacct gagtctttaa atttgaaatc tgattatctg
      541 cgccttgttt attactgttt atccgatttg aaagatttga aatctgagta gtggttcctt
      601 gctcactgct tgtaagtcta tttgaaaggc cactgatttg accgcccaca tcttgcttat
      661 aagtagttat ctgacttgaa atatccgtga acttaccatc tacagattga cgatagctag
      721 cgatttgact agcgatgtct ttattcgcac tagttttaac agcttcaatc ctctgattga
      781 tacccttaac atcttcttga taagtagcct taccaacgaa atcacgattg accagctcac
      841 ggactgctgt cgcttgtctc gtgctctcct cacgagtata gcgctgtagg gcttcctgtc
      901 gctgaccgtc tttatttaca tattcctgaa tagctgataa gtcggttcgc aagccctgag
      961 ctgtccgctc aaaggtagcc ttagcttcag t
//
LOCUS       DAVLDI010000128          931 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVLDI010000128 DAVLDI010000000
VERSION     DAVLDI010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..931
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.129"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(81..830)
                     /locus_tag="VXD01_002261"
     CDS             complement(81..830)
                     /locus_tag="VXD01_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV0602554.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPCVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
BASE COUNT          320 a          184 c          107 g          320 t
ORIGIN      
        1 tatttagatg caaatagtaa cgcgtaggcc agcccaacat gccccaaacc aattactgct
       61 atattcataa aactacttcc ttatttctta atccaaaatc taatagaata agctgcccca
      121 ttccttaaat acaactcttt aatattgttt aaaagttttt caactgattt ccagattatc
      181 aaaatctgag atttatagca caatattgat gatattctat caatataatg tttttcatca
      241 agttcctctt gatacatttt taattcttta gtttttccca tataactaac catactacta
      301 tcacttacac atgggaagtc ctcataatat attactttat aacgcataaa ttcaagcgcc
      361 cttccaatac tattcacaaa aacatgatca acatggtcac caagtgaaag cggacaatat
      421 acgacacatt tgtcgtctaa atgcattaac agctctttta tgatatcatt ctttaatgtg
      481 tcctcatttt ttaattcact atagatatga cggtatagaa aattgccatt tctatctttc
      541 ctatagagac attcatagta cgataagtgt ctaaaatcac attgtagacg ttcacaagct
      601 aacctgtctt ctttcttcct ttcttcaatc ggatatttcc caaggttaca caacttatga
      661 aattgcttag cagagggctg tagctgttgg ctcaaagggt aaccagaaaa tatagtaata
      721 acaagtacaa tttctccttc tgaagttaat tttgaaatat aatcaccaca ggaaaaaatt
      781 gcgtcatcta aatgtggaga taaaaagata tacttagtat tgttactcat aaccattccc
      841 tctacaattt atctaaaaac tcactaagtg tctgattaaa ttccacatca tcaaaaaaat
      901 tcaccttatt cttaataatg aatatttcgt t
//
LOCUS       DAVLDI010000129          930 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVLDI010000129 DAVLDI010000000
VERSION     DAVLDI010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.130"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..735
                     /locus_tag="VXD01_002262"
                     /pseudo
     CDS             1..735
                     /locus_tag="VXD01_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(854..927)
                     /locus_tag="VXD01_002263"
     tRNA            complement(854..927)
                     /locus_tag="VXD01_002263"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(891..893),aa:Asn,seq:gtt)
BASE COUNT          310 a          200 c          144 g          276 t
ORIGIN      
        1 aaaaatgatg gtcgctgaaa cttctatcgt caagaagaat catcaaattc cttgtatcat
       61 caaccaaaag attgctcaga agctaattga aaagacttct atgaccgaca ttgattatca
      121 gttgtctatt tcaactgtca ttcgcaagat caatgatttt cactttgagc atgatttttc
      181 gcgtcttcct gagattatgt cctaggacgt tgaaacagtc cagggagtga ctatttcaat
      241 cgggagatgg agatgagctt tattgctcag gactttgata agctcaatat cataactgtt
      301 cttgagagca gaacacaagc catcatacga aatcccatga atacaaggct atcaagcgct
      361 actggagctc attcaacaag atagtcagaa actgagtgat aaacgatttt atcgccctac
      421 ttttcgtatg cacttgacta ataaagaaat tctagataaa cttttgagct attcgaagac
      481 ttgaaacacc actataatct ctatcagcta taatctctat cagctcttgc ttttccacct
      541 ctttttcaga ctctgtttaa aaccttcctc aaagataaag aaaaaatcgt caacggcctt
      601 caattacctt attccaacgc caaactggaa gccaccaata atctcatcaa acttatcaag
      661 cacaatgcct ttggttttag gaactttgaa aacttcaaaa aagaaaggac gaaatttgtc
      721 ctttctcaag cttagctttt cttcaaccca ctacagttga caaagagcca ctatttttgg
      781 ttcattttac tataacacga aatagattat tattacataa taaaaaagag gtctaaacct
      841 cttaactaaa ttactccgcc agtaggactc gaacctacga catcatgatt aacagtcatg
      901 cgctactacc aactgagcta tggcggatta
//
LOCUS       DAVLDI010000130          884 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVLDI010000130 DAVLDI010000000
VERSION     DAVLDI010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..884
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.131"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..884
                     /locus_tag="VXD01_002264"
                     /pseudo
     CDS             1..884
                     /locus_tag="VXD01_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          273 a          190 c          163 g          258 t
ORIGIN      
        1 aaagatacac acaaggaaat catcgccaaa ctggactacg acgccccatc ttgccctgag
       61 tgcggaagtc aaatgaagaa atatgacttt caaaaacctt ctaagattcc ttatcttgaa
      121 acgactggta tgcctactag aattctcctt agaaagcgtc gattcaagtg ctatcactgt
      181 tcaaaaatga tggtcgctga aacttctatc gtcaagaaga atcaccaaat ccctcgtatc
      241 atcaaccaaa agattgcgca aaagttaatt gaaaagattt ctatgactga tattgcccat
      301 cagctttcca tctcaacttc aactgttatt cgtaagctca atgattttca ctttgagtgt
      361 aattttagaa atctgcctaa gattatgtct tgggacgttg aaacagtcca gggagtgact
      421 atttcaatcg ggagatggag atgagcttta ttgcgcaaga ttttgaaaag ctcgatatca
      481 tcactgttct taagggaaga acacaagctg tcatccgaaa tcactttctt aaatatgata
      541 gagccgtctg atgtcgcgtc aaaatcatta ctatggatat gtttagccct tactatggct
      601 tggctaaaca gcttcgcttt caaatttcta ggctcaggct gaaacagtct cccagactgt
      661 ttcactcccg aatgctaaaa tcgttcttga acgctttcac attgtgcaac atcttagccg
      721 tgctatgagt cgtgtgcgtg ttcaaatcat gaatcagttt catcgaaaat cccatgaata
      781 caaggctatc aagcgctact ggaagctcat acaacaggat agccgtaaac tgagtgataa
      841 gcgattttat cgtcctactt ttcgtatgca tttaccaata aaga
//
LOCUS       DAVLDI010000131          869 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVLDI010000131 DAVLDI010000000
VERSION     DAVLDI010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..869
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.132"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(23..850)
                     /locus_tag="VXD01_002265"
     CDS             complement(23..850)
                     /locus_tag="VXD01_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV0602555.1"
                     /translation="MPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGASLS
                     VVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSMAL
                     SSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLNAL
                     AMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISKDI
                     RTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVNN"
BASE COUNT          310 a          168 c          129 g          262 t
ORIGIN      
        1 atacctataa ttaaattttg cattagttat taacccctct atttttcata gttacataaa
       61 taagtactgg acccccgatt attgcagtaa ttatccctac ttcaatttca cctggtttac
      121 ctaacatacg gccgattata tcacatataa gcaagagctc tgcacctata aaagatgaag
      181 aaatggtcat tgtgcgtata tctttgctta taaataagcc acaaaagtga ggaactataa
      241 gacctacgaa gccaataggt ccaccaattg cagtaatact tgaacataaa agcacacttg
      301 caattattgc aagtgatctt atcctattaa cattaactcc aagaccaaca gccatttcat
      361 cacccatagc taaagcgttt aaatctgatg aaataaatat agctatcaag tgacctaaaa
      421 ttataaaagg tagtagtgta gatatagaag ataatgtagc tgctccaagg ctacctattt
      481 gccaaaatct aaatttgtct aagacgttat tattcggtaa aattaaaaaa cttacaaaac
      541 tgcttaaagc catactaaca caagttcctg ataaggcaag ttttataggg gtaaggcctg
      601 cttttccgct tacagcaatc gcgtatacaa aaattgcact tactaagcca ccaatgattg
      661 caaaacttat atggcttatg cttgatgaaa ttcctaaaaa agaaagacca attactacac
      721 taagacttgc tcctgtgttt ataccgagta tacctggatc agctattggg tttctagtaa
      781 ctgattgcat caatacaccg cttatggcaa gactagaacc tgctaaaatt gcaaaaatag
      841 ttctaggtat tcttttatat ataattgat
//
LOCUS       DAVLDI010000132          865 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVLDI010000132 DAVLDI010000000
VERSION     DAVLDI010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..865
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.133"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..>865
                     /locus_tag="VXD01_002266"
     CDS             <1..>865
                     /locus_tag="VXD01_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV0602556.1"
                     /translation="STRQATAVRELVNRDFVGKATYQEDVKGINQRIEAVKTSANKDI
                     ASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSEQGTTTQISNISNRI
                     NSNKQGTDNQISNLKTQVATNKDNAERQMGRISDQVSANKANADSQFANVTNQLARKV
                     ETTDFQRVKETSKLYERILGNTENGIADKVARMALTNQLFQVEVGKYSVSGPNLIKNS
                     DFKNATNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFLYSHRFNLERNTDYV
                     LNFRGFNNSALA"
BASE COUNT          303 a          147 c          189 g          226 t
ORIGIN      
        1 agcacgagac aagcgacagc agtccgtgag ctggtcaatc gtgatttcgt tggtaaggct
       61 acttatcaag aagatgttaa gggtatcaat cagaggattg aagctgttaa aactagtgcg
      121 aataaagaca tcgctagtca aatcgctagc tatcgtcaat ctgtagatgg taagttcacg
      181 gatatttcaa gtcagataac tacttataag caagatgtgg gcggtcaaat cagtggtcta
      241 tcaaatagac ttacaagcag tgagcaagga accactactc agatttcaaa tatttcaaat
      301 cggataaaca gtaataagca aggcacagat aatcagattt caaatttaaa gactcaggtc
      361 gctacaaaca aggataatgc tgaacgacaa atgggtagaa tatctgatca ggtttctgca
      421 aacaaagcga atgctgatag tcaatttgcg aatgtgacca atcaactagc gcgaaaagta
      481 gagactactg acttccagcg tgttaaggaa accagtaaac tttacgagcg aattttgggc
      541 aatactgaaa atggaattgc ggataaggtt gctcgcatgg ctctgactaa tcaactgttt
      601 caggttgagg ttgggaaata tagtgtaagc ggccctaacc tcattaagaa tagtgatttt
      661 aaaaatgcta cgaatgaatg gggctcaact caaaatttag gaagattggt taagcatagc
      721 ttttatcaca acgggcagaa agaccttatg cgtttaagta atgcaactaa aaacgaaaac
      781 tttttgtata gtcaccgttt taatcttgaa cgaaatactg actatgtact gaattttaga
      841 ggatttaaca acagtgctct cgcaa
//
LOCUS       DAVLDI010000133          838 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVLDI010000133 DAVLDI010000000
VERSION     DAVLDI010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.134"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(29..616)
                     /locus_tag="VXD01_002267"
     CDS             complement(29..616)
                     /locus_tag="VXD01_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV0602557.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQVLYGASLFS
                     FLWMYGQRKQVVKVNMKTRMKCLGIGLASLLIISLCFSLIHAQGSTNQTNLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNFLVYSLLLF"
     gene            complement(619..>838)
                     /locus_tag="VXD01_002268"
     CDS             complement(619..>838)
                     /locus_tag="VXD01_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV0602558.1"
                     /translation="WENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQKIRHYK
                     MEQRMPQSPWVERIVQILDLDYEDLFRR"
BASE COUNT          305 a          172 c          116 g          245 t
ORIGIN      
        1 atttatgaga taaatcaggt cacctatttt aaaaaagcag caaactataa actaaaaagt
       61 tccacaccaa atgtaacccc atacttcccc ataagtcaga tttatagcgc accataccta
      121 aaaacattcc aagtgaaacg tacagacacc aagctagaat ggttcctgga tgatgtacta
      181 aggcaaataa aacacttgtc aaagcaactc gaatatctaa ttttctaacc aagttccata
      241 aaatttcacg atacagaaat tcttcaacca tactcgcatt gattaagaac aataaaaatg
      301 aaaaccaagg aacttgatgt tgaaggccaa ttaaatttgt ttgattcgtg cttccttgag
      361 catgaatcag gctaaaacat agacttataa tcagtagact agctagtcca ataccaaggc
      421 atttcatcct agttttcata ttgaccttga ccacttgttt tcgttgacca tacatccata
      481 aaaaagaaaa aagagacgca ccatagagaa cctgtagtat agttaactca ccgatacaaa
      541 gaaatttcaa taagtataga gataccaata ggacatttac ttgttggaat atataaactg
      601 gaattattct tttcatagtt acctccgaaa taaatcttca taatctaaat ctaatatctg
      661 cacaatcctt tctacccatg gactttgagg cattcgttgt tccatcttgt agtggcgaat
      721 cttttgatat aaacgattca attcacttgg atagtgaaac tctcccgcaa acatttttct
      781 ggttaactca atccagctga tatttctttc agccaaaata atggacaagt tctcccaa
//
LOCUS       DAVLDI010000134          741 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVLDI010000134 DAVLDI010000000
VERSION     DAVLDI010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.135"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            86..268
                     /locus_tag="VXD01_002269"
     CDS             86..268
                     /locus_tag="VXD01_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0602559.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            278..643
                     /locus_tag="VXD01_002270"
     CDS             278..643
                     /locus_tag="VXD01_002270"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV0602560.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            640..>741
                     /locus_tag="VXD01_002271"
     CDS             640..>741
                     /locus_tag="VXD01_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV0602561.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKT"
BASE COUNT          308 a           98 c          122 g          213 t
ORIGIN      
        1 accgaattag aaagaaaaaa tcgaaaaatt agctaagaaa tattctgata acttaaacat
       61 caaagttcaa gagagagttc gtgaaatggc aaatgataat aagagccatt atttgatata
      121 cagagtttta ggtatttcat ttgaagaagg agaaaatatc gatttgtatc aaaataaagg
      181 tcgtttttta tacaaatatg ctggttcatt tttagaagaa gctgcagtac tatcctttaa
      241 cgaaaaattt ggtacagaaa atacttaaaa agttaacatt cctaattctg aaagtacaaa
      301 acctaagact tttgaaattg attgtttagt cggagaaaaa cacgcatacg aaataaaatg
      361 gtgggatgca actacagatg gagaccatat aactaaagaa cacactagaa taaaagttat
      421 tcataacaaa ggatatatac caattcggtt aatgttctac tatccaaata gaactcaagc
      481 tataaaaatt cagcaaactt tagaaacatt gtataacggt attggaggga aatattatta
      541 tggagattct gcctgggaac atttaagagc agtgaccggt attgatttac ttagtattct
      601 aacagatatt gcaaataaaa aaacaggggt aaaatcaaaa tgacagtatt aaaaggagat
      661 aacttagaaa tattaaaaac tattgaatcc tcaagtattg atttaatcta tatggaccct
      721 cctttcttta cacagaaaac c
//
LOCUS       DAVLDI010000135          652 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVLDI010000135 DAVLDI010000000
VERSION     DAVLDI010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.136"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(288..539)
                     /locus_tag="VXD01_002272"
     CDS             complement(288..539)
                     /locus_tag="VXD01_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000098314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602562.1"
                     /translation="MSSQMKAFLNELQGNMEVVGEFFDNPEKVIRKFGIVGREKEALL
                     IRDLNDMDDYALSIQNSVASPSGAHSSTCHFVRQDLQSA"
BASE COUNT          216 a          128 c           69 g          239 t
ORIGIN      
        1 tctagtgatt ctgataattc atccggaata attcttttaa catcgtattt atttttcata
       61 tcggccactc ttccttaaaa agctcacaat aaaattttaa atttctatac aacaatccga
      121 gagtagtctc acaatttgaa catttcacat cactcttaat atataaaaaa tgaattaatc
      181 agaaacctct gactaagatt tcctaattaa ttcactttct atatcatagt aaggaattct
      241 attatcccta attgaaaatt gaaattttat gttttatata ttaacaatta tgcggattgt
      301 aaatcttgtc taacaaaatg gcaagtgcta ctatgtgccc cagaaggcga tgcaacgcta
      361 ttttgaattg aaagagcata atcatccata tcatttaagt cacggattag caatgcttcc
      421 ttctctcttc cgacaattcc aaattttcta attacctttt caggattatc aaaaaattct
      481 ccaacaactt ccatatttcc ttgaagttca ttcaagaaag ctttcatttg actactcatt
      541 atatagctcc ttttctatta ctttatttgg aatcaaaact tacttgtaca ttggaaacac
      601 ctctattcta cgctttcata ttgctgcatg acactttcaa aatcaaattg ct
//
LOCUS       DAVLDI010000136          606 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVLDI010000136 DAVLDI010000000
VERSION     DAVLDI010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..606
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.137"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..>606)
                     /locus_tag="VXD01_002273"
     CDS             complement(<1..>606)
                     /locus_tag="VXD01_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV0602563.1"
                     /translation="HDFSCLPEIMSWDEYAFTKGKMSFIAQDFNNLNIITVLEGRTQA
                     IIRNHFLKYDRAVRCRVKIITMDMFSPYYDLARQLFPCAKIVLDRFHIVQHLSRAMSR
                     VRVQIMNQLDRKSHEYKAIKRYWKLIQQDSRKLSDKHFYRPTFRMHLTNKEILNKLLS
                     YSQDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQVHPL"
BASE COUNT          195 a          107 c          121 g          183 t
ORIGIN      
        1 aaaagaggat gaacctgctt tagattgtcc tcaatgagtc cgaaaaattt ctccggttcc
       61 ttattctgaa agtgaaacag caagagttga tagagctgat agtggtgttt caagtcttgt
      121 gaatagctca aaagcttgtt taaaatctct ttattggtta aatgcatacg aaaagtaggg
      181 cgataaaaat gtttatcgct gagtttacga ctatcctgtt gtatgagctt ccagtagcgc
      241 ttgatagcct tgtattcatg agactttcga tccaattgat tcatgatttg aacacgcaca
      301 cgactcatag cacggctaag atgttgtaca atgtgaaagc gatccaacac gattttagca
      361 catgggaaaa gttgtctagc taagtcatag taaggactaa acatatccat agtaataatt
      421 ttgacgcgac atcggacggc tctatcatat ttaagaaagt gatttcgaat gatagcttgt
      481 gttcttccct caagaacagt gatgatattg agattgttaa aatcttgcgc aatgaagctc
      541 atctttccct ttgtaaaagc atactcatcc caagacataa tctcaggaag acaagaaaaa
      601 tcatgt
//
LOCUS       DAVLDI010000137          587 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVLDI010000137 DAVLDI010000000
VERSION     DAVLDI010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.138"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            124..587
                     /locus_tag="VXD01_002274"
                     /pseudo
     CDS             124..587
                     /locus_tag="VXD01_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639853.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          200 a          105 c          145 g          137 t
ORIGIN      
        1 agcgcgagac aagcgacagc agtccgtgag ctggtcaatc gtgatttcgt tggtaaggct
       61 acttatcaag aagatgttaa gggtatcaat cagaggattg aagctgttaa aactagtgcg
      121 aatactgaag gccttagaac caaagccgat atcagcgcac tcaacgtgac tgctgaaaat
      181 atccggcaat ctgtgaagag tcttgagaca gacacgcaga acaagctaaa tcagaagttg
      241 agtcaggctg aatttgaggt gcgagccggc tctatccgtc aggaaatcct gaacgcaacc
      301 aaggataagg cagataagac tttagttgta tctgaagctg ggaaattgcg tgaagaattt
      361 tcaaaaatga aggtgggagg ccggaatcta tggataaaat ccaagacggt tggagctgta
      421 attgaaaaat tacctgaaaa ccatgtcaca ggtcaaaaag aatgttatag gttagagaac
      481 aactctactt taacgttcaa ccttgaacca gatttcagct caaggttgta tcaaaaagtt
      541 acttttagcg cttggatcaa gtacgaaaat gtagtccaag gtcgaaa
//
LOCUS       DAVLDI010000138          574 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVLDI010000138 DAVLDI010000000
VERSION     DAVLDI010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..574
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.139"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..459
                     /locus_tag="VXD01_002275"
                     /pseudo
     CDS             1..459
                     /locus_tag="VXD01_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001009003.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            454..>574
                     /locus_tag="VXD01_002276"
     CDS             454..>574
                     /locus_tag="VXD01_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV0602564.1"
                     /translation="MESLSDDDYDFAFDEALFRFSILNANHFLSKEDIDYLRVN"
BASE COUNT          224 a           79 c           80 g          191 t
ORIGIN      
        1 gaattaatta caagaataat taataatgtt aacattgaca atttagatat tccgttcgaa
       61 tttaaactaa caaaagaagc acaaaatctt attatcgaac atagtgacta tatcaaagca
      121 tactatgata aagacataac tatggaagat tattgtaaag aaaaaaacaa tatctctttt
      181 aaagcaactt ttggtgatat aaaatggagt ctcttaaata aacaagctca taggaatact
      241 gtatcaggag attttggatg cttatctaac acacgaaagg ctcagggaag acatttggaa
      301 caagaaggta atattaaaca tgctttaata tattacatag aatctttgat aattactatt
      361 tcaggattag aaaacaattt ttcagccact gattatccag tatattatcc cgattcgata
      421 cctgactact cactaaaaca tattcaaaca ttaatggaat cattatctga tgacgattat
      481 gattttgctt ttgatgaagc attatttcgc ttctcaattt tgaatgcaaa tcatttttta
      541 tctaaggaag atattgacta tttaagagtt aatt
//
LOCUS       DAVLDI010000139          552 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVLDI010000139 DAVLDI010000000
VERSION     DAVLDI010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..552
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.140"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            164..301
                     /locus_tag="VXD01_002277"
     CDS             164..301
                     /locus_tag="VXD01_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV0602565.1"
                     /translation="MAAEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
BASE COUNT          176 a           61 c          121 g          194 t
ORIGIN      
        1 tatctttaag aatgcaaaaa ttatttctta aaaatttgta agttttcgct atataaaata
       61 gttaaatcta ttttgtatca ttgcttgcat tttactggtg gagagagtat atgagggtgg
      121 ataaagtact taatcccaaa aatttaaata ggaggagcta gctatggcag cagaagtatt
      181 aaatcttcaa ttagtatctg ttcaagttga cgaaacagat gaagttgatg gaatgcgatt
      241 tagtacattc agtacaaacc gttgcggtaa ctggagtgct tttagttggg aaaattgtta
      301 attcatttaa attgtaaact ttagagattc tctggagtta tggatgtcgt tccaatatgt
      361 gcacgttgga atgttagtgc ttatatgggg gaacagaatc ctctcttgat tgaagacaag
      421 ctagtcatta ggctggtttg tctttttgtc aactgtagtg ggttgatata atagtattag
      481 tgagtgggat aaaagtttca tttagtttat tcagtacaaa tttaacgggt caagatttaa
      541 ctaaaggaga ag
//
LOCUS       DAVLDI010000140          547 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.141, whole genome shotgun sequence.
ACCESSION   DAVLDI010000140 DAVLDI010000000
VERSION     DAVLDI010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..547
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.141"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(1..547)
                     /locus_tag="VXD01_002278"
                     /pseudo
     CDS             complement(1..547)
                     /locus_tag="VXD01_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          163 a           96 c          123 g          165 t
ORIGIN      
        1 cctgcttaag attgtcctcg ataagttcga aaaatttctc tggttcctta ttctggaagt
       61 gaaaaagcaa gagctgatag agctgatagt ggtgtttcaa gtcttccgaa taactcaaaa
      121 gcttgtttaa aatctcttta ttggttaagt gcatacgaaa agtaggacga taaaattgct
      181 tatcactcag tttacggcta tcctgttgta tgagcttcca gtagtgcttg atagccttgt
      241 gttcatggga ttttcgatga aactgattca tgatttggac acgcacacga ctcatagcac
      301 ggctaagatg ttgtacaatg tgaaagcgat caagaacgat tttagcattc gggagtgaaa
      361 cagtctagga gactgtttca gcctgagcct agaaatttga aagcgaagct gtttagccaa
      421 gtcatagtaa gggctaaaca tatccatagt aatgattttg acgcgacatc ggacggctct
      481 atcatattta agaaagtgat ctcggatgac agcttgtgtt ctaccttcaa gaacagtgat
      541 gatatcg
//
LOCUS       DAVLDI010000141          510 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.142, whole genome shotgun sequence.
ACCESSION   DAVLDI010000141 DAVLDI010000000
VERSION     DAVLDI010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.142"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..>510
                     /locus_tag="VXD01_002279"
     CDS             <1..>510
                     /locus_tag="VXD01_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602566.1"
                     /translation="KQVESALNQLKSSVQNTDLIKMDIENGKLKHLIGNLEFFTDDFL
                     AKVNLFVRDEITDKEDEVYKELLNIISDSIGDVYEQEWIYEIEKEGEKRFAEAIPPGF
                     NDENKDGIRKYNGISYHQKYGDLIIWKDILKKATEQPRGDKVIFITNDGESNKKSDLI
                     YKTSNMKVGP"
BASE COUNT          209 a           42 c           97 g          162 t
ORIGIN      
        1 taaacaagtt gaatctgcat tgaatcaatt aaaatcaagt gtacagaata ctgatttaat
       61 taaaatggat attgagaatg gtaaactaaa acatttgatt gggaatttgg agttttttac
      121 tgatgatttt ttggctaagg tgaatttatt tgtaagagat gaaattactg ataaagaaga
      181 tgaagtttat aaagagttac ttaatattat ttctgattct attggagatg tgtatgagca
      241 ggaatggata tatgaaatag aaaaagaagg agaaaaacgt tttgcagaag ctattccacc
      301 gggatttaat gacgaaaata aagatggaat aagaaaatat aatggcatat cttatcatca
      361 aaaatatggt gatttaatta tttggaagga tatattaaaa aaagcaacgg aacaacctcg
      421 tggtgataaa gttatcttta ttactaatga cggagaatca aataaaaaaa gtgatttaat
      481 ttataaaact tcaaatatga aagttggtcc
//
LOCUS       DAVLDI010000142          506 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.143, whole genome shotgun sequence.
ACCESSION   DAVLDI010000142 DAVLDI010000000
VERSION     DAVLDI010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.143"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(168..>506)
                     /locus_tag="VXD01_002280"
     CDS             complement(168..>506)
                     /locus_tag="VXD01_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV0602567.1"
                     /translation="KPSEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEESPEESE
                     EPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAE
                     KLLALLKESK"
BASE COUNT          101 a          104 c           88 g          213 t
ORIGIN      
        1 gatttctaac aatgttttag aagtagaggt atactattct agtttcaatc tactatattt
       61 tgcacatttt catgaaaaaa atgagaacta gaactcacat tctgctctca tttttcgttt
      121 tcccgttctc ctatcctgtt tttaggagtt agaaaatgct gctaccttta cttactctcc
      181 tttaataaag ccaatagttt ttcagcttct gccataatag tattgttgtc ctgggtgcca
      241 aatagtaaat tattttttaa tcctgtgaga gtctctttgg cattggactt gataattgga
      301 tcctggattt ttccaagtaa atcttcagcc tctctcagtt tttcttcaac cttttcagtc
      361 tcgacctgag gttcttctga ttcctctggt gattcttctg gttcctctgt tggttttgga
      421 gactctggtt tctcgctttg cggtttctct tctcgagggg tttcttcctc aggtttttct
      481 gtctgaggtt tctcctcgct tggttt
//
LOCUS       DAVLDI010000143          459 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.144, whole genome shotgun sequence.
ACCESSION   DAVLDI010000143 DAVLDI010000000
VERSION     DAVLDI010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.144"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..>459
                     /locus_tag="VXD01_002281"
     CDS             <1..>459
                     /locus_tag="VXD01_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV0602568.1"
                     /translation="IELAIKLIREANQILIIGVGSSGNAAREFESSLLRIGIISKTVI
                     DTHFQLMHTALLKDNDLIIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKL
                     SDCVLLTSKKESYLEGGSLMAKASQLFIIDVICTRLSLINYEDTICKKEE"
BASE COUNT          179 a           50 c           82 g          148 t
ORIGIN      
        1 aatagaatta gctataaaat taataagaga agcaaaccag attttaatta ttggtgtggg
       61 ttctagtgga aatgcggcta gagaatttga gagtagtttg ttaagaattg gaataataag
      121 taagacggta attgataccc attttcaact catgcatact gcgttattga aagataatga
      181 tttgataata gcgtttagtt tatctggttc cacaaaagaa gttgaggaaa ctttattaaa
      241 cgcaaaaaga aaaaatgtta aaattatttc aataacaaat tattcgtcca gaaatatagc
      301 aaaattatct gactgcgttc ttttgacatc aaaaaaagaa tcttatttag agggtggtag
      361 tttaatggct aaggcttctc aactattcat aattgatgta atatgcacta gactctcttt
      421 aataaattat gaagatacta tatgtaaaaa agaagagat
//
LOCUS       DAVLDI010000144          438 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.145, whole genome shotgun sequence.
ACCESSION   DAVLDI010000144 DAVLDI010000000
VERSION     DAVLDI010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.145"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..>438
                     /locus_tag="VXD01_002282"
     CDS             <1..>438
                     /locus_tag="VXD01_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV0602569.1"
                     /translation="RRAGESDGFTIVKKVVSSKKLSTSRCEDVSVTFNSGEMDNAYIR
                     FDNNGSSSGTADLYITEVDLYKGYKPRTWQPHPEDAVADANKKLEATQTKMTQLAGSW
                     VVENINSAGDIISGINLGANGHNRFVGKLTHITGETLIDRAVI"
BASE COUNT          150 a           88 c           97 g          103 t
ORIGIN      
        1 acgaagagca ggcgagagcg atggattcac aatcgttaag aaagttgtta gcagcaagaa
       61 actatctacc tctagatgcg aagatgtctc agtaactttt aattccggag aaatggataa
      121 tgcttacatt cgttttgata acaatggctc atcatcagga acagctgatt tgtatattac
      181 agaagttgac ttgtacaaag gttataaacc tagaacatgg caaccacatc cagaagatgc
      241 agtcgcagat gcgaataaga agcttgaagc aacgcaaaca aaaatgactc aactagctgg
      301 ctcatgggta gttgaaaaca tcaactcggc tggagatatc atctctggaa tcaatcttgg
      361 cgccaatgga cataaccgct tcgttgggaa attgacccac atcactggag agaccctgat
      421 tgacagagca gtcatcaa
//
LOCUS       DAVLDI010000145          362 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.146, whole genome shotgun sequence.
ACCESSION   DAVLDI010000145 DAVLDI010000000
VERSION     DAVLDI010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.146"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            199..>362
                     /locus_tag="VXD01_002283"
     CDS             199..>362
                     /locus_tag="VXD01_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HEV0602570.1"
                     /translation="MNVPIRDYYIPRYNTIPDQYIILEVISKNAKGGVYKVFNTQKRV
                     YSLLKEASDLS"
BASE COUNT          141 a           43 c           61 g          117 t
ORIGIN      
        1 attacaattt atccaaaaga taataaagag tttcaacgtt tgttacacaa attagaaata
       61 ttgtataaag gtgtaaaggg tgtaaacata ccatcagatt tcagatttca acttagcgag
      121 gttgtatatt acagatatgg ggagttcgta aaagatagca ctttcaagga taaaagagat
      181 aagaaaatcc cttcaaatgt gaatgttcca ataagggatt actatattcc aagatataac
      241 actattcctg atcaatatat tattttggaa gtgatttcta aaaatgccaa aggtggagtt
      301 tataaagtat ttaatactca aaagcgagtt tattctttat taaaagaagc tagtgattta
      361 tc
//
LOCUS       DAVLDI010000146          361 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.denovo.147, whole genome shotgun sequence.
ACCESSION   DAVLDI010000146 DAVLDI010000000
VERSION     DAVLDI010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.denovo.147"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..>361)
                     /locus_tag="VXD01_002284"
     CDS             complement(<1..>361)
                     /locus_tag="VXD01_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602571.1"
                     /translation="ISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGA
                     PILIVLANIISIAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFL
                     LNIKIMALIYYSLEDILI"
BASE COUNT          142 a           55 c           46 g          118 t
ORIGIN      
        1 tattaaaata tcctctaaag agtagtatat taaagccata attttaatgt taagtaaaaa
       61 tgcaattaat gaagtaacaa atgtcaaaaa tatagcctca ccaactttaa tcttaaccat
      121 ctggtaatta gaagttccta aaatttcaaa ttgctgaatc tcaatccttt cttgatgcga
      181 tgacaaaaat gcaattgaaa taatatttgc aagtactatc aaaattggtg ctcctacata
      241 gacaataaat gctactttta gctctaaatc actgtcatct tgaaattgag atagtatatt
      301 ctgagaaatc atttgaaaac tagaaattag taatatagct cctgtaattg cagcactgat
      361 a
//
LOCUS       DAVLDI010000147        10370 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00036539
            SAMN33606979-rid17936503.guided.071, whole genome shotgun sequence.
ACCESSION   DAVLDI010000147 DAVLDI010000000
VERSION     DAVLDI010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606979
            Sequence Read Archive: SRR23726071
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721948.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721948.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:22:02
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,297
            CDSs (total)                      :: 2,248
            Genes (coding)                    :: 2,112
            CDSs (with protein)               :: 2,112
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 74 of 136
            Pseudo Genes (incomplete)         :: 63 of 136
            Pseudo Genes (internal stop)      :: 30 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10370
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606979-rid17936503.guided.071"
                     /strain="AUSMDU00036539"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            46..255
                     /locus_tag="VXD01_002285"
     CDS             46..255
                     /locus_tag="VXD01_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV0602572.1"
                     /translation="MKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTVLP
                     DIKIKLPIDSRGTPDWNYMERYRDR"
     gene            221..534
                     /locus_tag="VXD01_002286"
                     /pseudo
     CDS             221..534
                     /locus_tag="VXD01_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1218..1379
                     /locus_tag="VXD01_002287"
     CDS             1218..1379
                     /locus_tag="VXD01_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602573.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1471..3150
                     /locus_tag="VXD01_002288"
     CDS             1471..3150
                     /locus_tag="VXD01_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV0602574.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEDCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            3418..3984
                     /locus_tag="VXD01_002289"
     CDS             3418..3984
                     /locus_tag="VXD01_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602575.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4306..4494
                     /locus_tag="VXD01_002290"
     CDS             4306..4494
                     /locus_tag="VXD01_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV0602576.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4556..5314
                     /locus_tag="VXD01_002291"
     CDS             4556..5314
                     /locus_tag="VXD01_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV0602577.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            5372..5833
                     /locus_tag="VXD01_002292"
     CDS             5372..5833
                     /locus_tag="VXD01_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0602578.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRF"
     gene            5867..6226
                     /locus_tag="VXD01_002293"
     CDS             5867..6226
                     /locus_tag="VXD01_002293"
                     /inference="COORDINATES: protein motif:HMM:NF015692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV0602579.1"
                     /translation="MNDNPIECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQET
                     VPQAIIAFLESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLD
                     EPLKDVVRRWENRIKVY"
     gene            6338..7222
                     /locus_tag="VXD01_002294"
     CDS             6338..7222
                     /locus_tag="VXD01_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV0602580.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKQGILA
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7385..9124
                     /locus_tag="VXD01_002295"
     CDS             7385..9124
                     /locus_tag="VXD01_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV0602581.1"
                     /translation="MELSAIYHRTESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            9399..9701
                     /locus_tag="VXD01_002296"
     CDS             9399..9701
                     /locus_tag="VXD01_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV0602582.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            9757..10185
                     /locus_tag="VXD01_002297"
     CDS             9757..10185
                     /locus_tag="VXD01_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV0602583.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
BASE COUNT         3733 a         1414 c         2151 g         3072 t
ORIGIN      
        1 tttttaggag cagtctttta tcataaatat aaagcaagcc tagatatgaa aattcattgt
       61 ttaaaattaa aaaataaaga attgaataaa gaagtagcat tctatttaac ttcaattatt
      121 aggcaagctt taaaaaatac tgaatataaa gatcaaatat ctagcacagt attgccagat
      181 atcaaaatta aattaccgat agacagtaga ggtactccag attggaatta catggaaaga
      241 tatagagata gataaagaga gagggagaga tagataaaaa gtccaccccc atttttttat
      301 ggagaattca aaaatgtaag gttaagcaaa gaagaatata aaaatctaaa agaaaaatta
      361 aactcacaca cagatataat gataaataaa ctatccagat acatggaaag cagtggtaag
      421 acctatcaaa accactatgt gacaatctta aaatggtatg aagaagataa agacaaacta
      481 agacagaaag gtttaaataa aaaaatgaat tatgatgtag gagaatcttt atagataaaa
      541 agaggtggaa aggcactatt aaagacttta agtctaaaaa ggtatcaaag tatgccagag
      601 ataaaaaaat ataaatatga cactttaaag gtgattagaa aattaaagaa atgctagaag
      661 acttttagat gacagttacc aagagggtct aattttcact gctacttatg cagtgggaat
      721 tggacctttt tatataagca aattctattt caaaattggt taccaagaaa gacttctttt
      781 cactgttaag tataagaggg taatttatag aattttgtta cattaagata aatattttct
      841 gatggtcaaa ttttaaaaag attaataatt ctcgataaat tttgaacctt aacaattgaa
      901 tagaccaaga caagacgtta attatttttg gagcgtaata acctatccgt caagatcttt
      961 cggctgaata attcggcaaa aaaagttctg ctaagtaaaa agaaagtgag cgataagtaa
     1021 gagtttgaat atagggaggg ataccctatc cgctatgaag aaaatgagga taatgatact
     1081 tctaaggttg aagccggctc atccggaata gaggcggagg tgagattcct atgttgctaa
     1141 tccaaagcac ttgtcaatgt caaaaaactt aattaaacaa ataattatta gatataaaac
     1201 tttagaggag gtatatattg gacaatgact ggaatggatt ggctgattta atagcaaatc
     1261 tgattgcaaa atatgctggt gctttagatt tagataatct acccgatcca acgccagcaa
     1321 aaaatcaaga gatgaaaaat agttttgaca tggcaaaaac acaaattgag acggactaat
     1381 aaaagtgtta taatatactt gaaatgatag tccaaactta aattaaaaaa attatatatg
     1441 atatagaaaa attatattga ggttaatact atgtcaaaag aaaaaataaa agtatacctc
     1501 tatacacgag tatctacgtc aatacagata gaggggtatt cgttagaggc acaaaaatca
     1561 cgaatgaaag cttttgctat ttacaacgat tatgaaattg ttggagagta tgaagatgcc
     1621 gggaagtctg gcaagtctat tgaaggtaga atacagttca atcgaatgat ggaagatata
     1681 aaatctggaa aagatggagt atcttttgtt cttgtgttta agttatcaag atttgcaaga
     1741 aatgccgctg atgttctttc tacacttcag ataatgcagg attatggagt taatcttatc
     1801 tgcgttgaag atggcattga ttcatctaaa gatgctggga aactaatgat ttctgtttta
     1861 tcagctgtgg ctgaaataga aagagaaaac atccgtattc aaacaatgga agattgcatt
     1921 caaaaagcaa gggaaggaaa atggaatggt ggctttgctc cgtatggata taaacttgaa
     1981 gacggcaagc tgtttataaa tgaggaagag gcagttgcaa taagaacgat tttcgaccag
     2041 tatgtaaata ctacgatagg agccaatggg atatctaaat acttagagaa tcatggaatt
     2101 agaaaaatcc caagacagaa tggtaagaat cctttgtttg atgcaggtct tataagaaag
     2161 atattaaaga atcctgtata taatgggaaa atagcatttg gaagaagaac tttagaaaaa
     2221 gttcatggta caagaaatga atataagcag gttgaacaag atgaatatct aatatctgaa
     2281 gggatacatg aagctatagt ttccgatgaa gtttggcaag ctgctcaggt taagctaaaa
     2341 tctcaagcaa agaaatatga gcatgtgaat aaaggaaaag atacacgcac acacttgctt
     2401 tctggaattg taaaatgccc gatatgtgga gtgggaatgt ttgggaacaa gtgtatcaag
     2461 aaaaagaaag atggcacaaa gtataaagat ttttattact atggttgtaa acataggcag
     2521 atgataagag gtcataagtg tacattcagt aagcaaatta gagaagaatt gttagatgat
     2581 gctgttgcag aggtgattgt caagatagta agtaatccga aatttgcttc tatgatgcaa
     2641 gaaaaaatca acatgaaggt ggatacctct gaaatagaaa aagaaataga taattaccaa
     2701 aaggaattga gaaagagtca ttctacaaag tttaagctaa ttgaggaaat agataattta
     2761 gatgttgaag ataagcacta taagagaagg aaacaggatt tagatgatag actatatcgt
     2821 atgtatgaca aaatagatga attagaatca tcactaattg atgcgaaagc aaagaaacag
     2881 actattgaag ctgaaaaact tacaggagat aacatatata aggttctgat ctattttgat
     2941 aagctctata aagtcatgaa tgatgtagag cgtaggcagt taatttcagc tttgatttct
     3001 gaaattcaag tttatgaaga aaaacaatct aacggacaat ggctaaaatc cattactttt
     3061 aagctaccaa ttatagaaga aaatctcaac atagatttgg acaatgatga acaagttgaa
     3121 tgtgtaagtt tattagagaa acgtagttaa tcctcaaaag gttccccaaa ctttttgagt
     3181 cccactgacg catcacgctg aggcggtatc actgcttgta cgagttgaag catcagcgaa
     3241 gtaaaagtag atgttcagcc aatgcgacga ggtgagaccg aaggtcgata aggtgtgttc
     3301 tgggtatagg actcgtaaag taagtaggaa atatgatgag atgatacaga gagcctgaat
     3361 tggtcaggtg acgtgcttat ttacattagc ctgataatga aaatggagag attatcgatg
     3421 gttatattgg aattgtacca aaatgattat tctaaagatt tagtagcatt tgattccata
     3481 gaagatggga aagcctttgt ggctcaaatc ccgggataca ctctggaaac agaagatggt
     3541 tttgaagtgg agtattttaa tcctaaaaac ataccggatt atatggaaat tatttttaac
     3601 ggaaatattg ttcctttatc taaatttatg ttcgatcctg aggaaaatgt aaatattatt
     3661 tggaaagaga tttcaaattt atccctcaaa aatgatagag tgatcgaagg atattcaaaa
     3721 attgatgcat atgtcgttaa caaccatgaa gttaaagcct atgtcgaaac aagagaaacg
     3781 aactatcgta aagcaaaaga cttcttagaa agccgcggat atgaaatcga cagaagcttt
     3841 ttcggaagtg aagacggtga agcgattctt tacagaaaaa aagggatcga agtttggcat
     3901 ttcttgtgtc acttagaccc aatgtttgta gagattgaag atgtagaagg atatgttaaa
     3961 gaagaagttg gagagattca atagtcaacc aaagttcctt gtgagtatat acctttgcta
     4021 gtaaaagagt caaaacgtta taacgaaggg ggggaagaaa acccttgagt gtaagtcttt
     4081 ttcttgttta gagggaaagt attagagtag ccgctcataa tttatactag atttgataac
     4141 tgatttgaga cagattttat ttctataaat attgtgaaaa ttttttaata ccaaagattt
     4201 aaagttactg tgttaaaaat cctctccact tttaaactaa tgtattataa aagccagttg
     4261 acacaagtgt tacacctgtg atagaattaa cttgaggtga tgaaaatggc aaccgataaa
     4321 aatagaataa tgattagctt ggatgataaa aatctagaga aacttgaaaa tttagtagaa
     4381 gatgctagag atagaagggg aatgcgacta acaaagtccc aggttattga attactccta
     4441 aataccgttg attatttcga tgatattatg ggggctattt actcaaaaaa ataagagcaa
     4501 aattgctatt attttttaca aattggtgta acactagtga tataggagtg atgaaatggt
     4561 tgtttatatt agacaaagta aattaccaag tgaggtttca attaataaat acaatgctca
     4621 agtaggtgcc tacttacaag gagaagaagc tgttttatat caatcttttt ctgaaataaa
     4681 agagttaaca agtgaagata tagttgtaga ttatataatg gagactagag cattactaaa
     4741 aatgatgggc ttaaacgttc cggttcatga ctatcctatt gagcttaaag agttttatgg
     4801 tcgaaagatt tatgctggta ttttaggaga gattgtgaat atacctgata attggggaaa
     4861 atttattaag cctaaagctg gttcaaaagt ctttactgga agagttgtta atggaaccca
     4921 tgatttaata ggtattggtc tacctttcga ctatcctata tggattagtg aggttgtaga
     4981 attcatagct gaatggcgtt gttttgtgtt agatggtcgc gtattagatg ttcgacccta
     5041 tacaggtgat tatcatgcac aatttgatgc aagtgtaatt gatgaagcga tatcatgttg
     5101 gaaagatgcg ccaatagctt atggactaga tatcggtgtt actcgcgatg gcagaacact
     5161 tgttgttgaa gtaaatgatg gttatgcatt gggaaattat ggcctatctc ctttaaaatc
     5221 aatcaatttt catagagcta ggtggaaaga aatggtaaaa ccctattttg aaaaaaatga
     5281 aatttttaaa atccaacagg atgttgtttt ctaaaataaa tatggtatat aaccaatata
     5341 aaaagcatca aaatgaacaa ggaggaatct gatgcttgga gcaattattg gagatattgt
     5401 cggttctgtt tacgaatgga acaatatcaa aacaaaggac tttcctttat ttcggaagga
     5461 ctgctttttt acagatgaca cggttatgac ctgtgctgtt gcagaagcaa ttatgaatgg
     5521 tggacaaaaa gacgacttca ttgacgcgat gaagaaatat ggcagaatgt atccgaatgc
     5581 tgattacggt gctcggttta atgcatggct aaacagcgat aaccgtgagc cttataatag
     5641 ctttgggaat ggatcagcta tgcgtatttc tccatgtgct tggatcatgg actgtggttt
     5701 ttatgcgaaa actggtatat ggccatcatc tagaggactt acgagtcttt ctgcagaggt
     5761 aactcataat catccagaag gtgtcaaagg cgctatggct acagctgatg ctatctttct
     5821 atgtcgtttt taatttggtg gttattgtag agagtacgag taatcaatta acgacaatcc
     5881 tatagagtgt aaaagacgaa ttaaggatta tatagaaaaa gaatacgatt acaatctatc
     5941 tcaaacttta gatgaaatcc gtcctaacta tcgttttaac gaaacatgtc aggaaactgt
     6001 ccctcaagcc attatcgcct ttcttgaaag tagagacttc gaagatgcga taagaaatgc
     6061 catctcactt ggtggcgaca gtgatactct cgcagcaatc acttgtagca tagcagaggc
     6121 agcttacggt attcctgatt ggatcaagga taaggcctat tcttacttgg atgaaccctt
     6181 aaaggatgta gttaggcgat gggaaaatag aataaaagtg tattaatctc cagtacgtca
     6241 gatttctctt ttctgtattt tcattgtata ataggattac atttacttgc atacgacgaa
     6301 atgtaaacat ttctatttaa aattaaggat aaaatcaatg aaaaaagcaa tggtaattat
     6361 caaccctact tctggtggcg agaaggcttt ggattacaaa gaaaagctgg agaataaagc
     6421 aaaagaatac tttgaatatg ttgaaaccaa aattaccgaa aaagcgctgg atgcaacaca
     6481 ttttgctgaa gaagcttctc gtgagcagta tgatgcagtg gttgtgtttg gtggagatgg
     6541 gactgtcaat gaagtcattt caggtattga tgagagagac tacattccta agttagggat
     6601 tatcccaggc ggtacgggta acctcattac aaaacttttg gaaatcaatc aagacatcga
     6661 tggcgcaatt gacgaactgg attttgattt aaccaataag attgatatcg gtaaagcaaa
     6721 tgacaactat tttggttata tctttagtat cggttctctg cctgaggcga ttcacaatgt
     6781 tgaaatagag gacaaaacaa aacaaggtat tttagcctat gctgtaaata ctatgaagtc
     6841 tgtcatgaca gatcaggtct ttaacattaa ggttgagaca gaaaatggaa attatgttgg
     6901 tgaagctagc catgttttgg tccttttgac aaattacttc gctgataaga aaatctttga
     6961 agaaaacaag gacggctatg ccaacatttt gattctgaaa gatgcctcta tattctccaa
     7021 attatccgtc attcctgatt tattaaaagg ggatgttatc gcaaatgata atatcgagta
     7081 tatcaaagcg cgtaatatta aaatctcttc agatagtgaa ttggagtcag atgttgacgg
     7141 agataaatca gataacctac ctgtagaaat caaagtccta gctcagcgag tagaagtatt
     7201 ttcaaaaccg aaagaggatt agtatataga gaaagccttt tttaaggctt tttgtatact
     7261 ttaaaagata gttcctttaa caacggacat tccttgcaaa tagttcacaa aaatagtata
     7321 ctggattcat tgagtttgaa aacgtttgcg taaaatttga atgaatactt taggagataa
     7381 attgatggaa ttgagtgcta tttaccatag gactgagtcg gagtatgcct atctttataa
     7441 ggataagaaa ctccatattc gaattcgaac taagaaaggg gacattgaaa gcatcaactt
     7501 gcactatggg gaccctttta tctttatgga ggagttttat caggatacaa aagaaatggt
     7561 caagataact tctggtacct tatttgacca ttggcaggtt gaagtgtcag ttgactttgc
     7621 acgtatccag tatctttttg agctcagaga tacagaaggt caaaatattt tgtatggcga
     7681 taaagggtgt gtggaaaatt ctctagaaaa tcttcatgca attgggaatg gatttaagtt
     7741 gccttatctt catgagattg atgcctgcaa ggttcctgac tgggtttcaa atacggtatg
     7801 gtatcagata tttcctgaaa gatttgccaa tggcaatgct ctattaaacc cagaagggac
     7861 tttagactgg gattcatctg tcacacctaa gagcgatgat ttctttggtg gtgatttaca
     7921 ggggattatt gatcatatgg attacttgca agacttgggt attactggac tatatctttg
     7981 tcccatcttt gaatctacaa gcaatcacaa gtacaatacg acagattact ttgaaattga
     8041 ccgtcatttt ggagacaagg agacctttcg ggaactggtg gatcaagcgc atcatcgtgg
     8101 catgaaagtc atgctggatg cggtatttaa tcatattggt tcgcaatctc ttcaatggaa
     8161 aaatgtcgtc aaaaatggtg aacagtctgc ttataaggat tggttccata ttcaacaatt
     8221 cccagtgaca actgaaaagc tagttaataa gagagactta ccctatcatg tttttggttt
     8281 cgaggactat atgcctaagc taaatacagc caatccagag gtcaagaatt atcttttaaa
     8341 ggttgcgact tattggattg aagagtttaa tatcgatgct tggcgtttgg atgtggctaa
     8401 tgagattgac catcagttct ggaaggattt tcgtaaggca gttttagcta aaaatcctga
     8461 tctttatatc ctaggagaag tctggcatac atctcagcct tggctaaatg gagatgagtt
     8521 ccatgccgtc atgaattatc ctttatctga tagtatcaag gactatttct tacgaggaat
     8581 taagaagaca gaccagttca tcgatgaaat caatggagag tctatgtatt acaagcagca
     8641 gatttcagag gtcatgttta atctcttgga ttcacatgat acagagcgaa tcctgtggac
     8701 ggccaatgaa gatgttcaac tggttaaatc agccttagcc tttctctttt tacaaaaagg
     8761 aacaccgtgc atttattacg gaaccgagct agccttgact ggaggaccag atccagattg
     8821 tcgtcgttgt atgccttggg aacgtgtatc aagtgacaat gatatgctga actttatgaa
     8881 gaggctgatt aagattcgga aatacgcgtc agtaatcatt tcgcatggca agtatagcct
     8941 tcaagaaatc aaatctgatc tagtagctct ggaatggaaa tacgaaggac ggatcctcaa
     9001 agcaatattc aaccaatcaa cagaagatta tcttttagag aaagaagcag tagcactagc
     9061 aagcaattgc caagaattgg agaatcagct tgtcatctct ccagatggat ttgtgatttt
     9121 ctaaaaacta gttgatgaag attatggtac atttcatatc ttatatagta taataaggct
     9181 agttactaaa cttgtaaagg agaacttaaa tgaattgtag aggacacgaa acaagacaaa
     9241 gaattgttag agattttgaa gtttagccta aagcacatat taagctgtta gcaaatcaac
     9301 aaaaacatag tgatgcagga gcaactattg aagatgaata ttatgtattt atcgctgaga
     9361 gtaaaattga tggcaagaag gaagttattc agtgttgcat gggtgcggca agggattttt
     9421 tagaactaat taatcacaaa gggctacctc tttttaatcc gcttgtaggt gattctcatg
     9481 taaataatag acaagaatat gacaatacag ggagtggaaa tttacaacct gaaaagtgga
     9541 atgaaactgc aaagcagctt tataatgtta taatgtggtt gattatttta tggaatgcta
     9601 agccggatac acctttattt aattttaaag acgaagtaat taagtataaa acatatgagc
     9661 cttttgaaag cagtataaaa ttggtatcaa tcaatgagta acaaagtatc agcatgattc
     9721 gaaacattta cttgtaattt gcggaggaac atcaatatgg atggaataac aaaagatttt
     9781 ataaaaacgg ctaaactaat gaaacaatta tggccccaat tgaccgataa agaagctatt
     9841 gatgaagtaa aaaaatatac gaatggcaaa aatactgcaa tctttactga agttgaaggt
     9901 gacacaattg taggtctagc actatgttca ctcagatttg attatgttga aggttgtaaa
     9961 tatagtcctg ttggattctt agaagggatt attgttgacg aggaatatcg tttaaaggat
    10021 attgctaaaa atctctgtac aaaatgtgag gaatgggcga aaaataaagg atgtaaggaa
    10081 tttgcaagtg actgtacttt aacgaatacg gattctataa gatttcatct caatattgga
    10141 tttcaggagg caaatagaat tattcatttt aagaaaaaat tataatttag aaacgtgaat
    10201 aaacttgttt aaactttatg tatctttaga aagtgtgtta acttgaaaga acaaattttt
    10261 ttgatgggtg ggaatccccc aatgaagaaa tatagtattg ttgataaaat tgtattatca
    10321 accaagatta aaagaattat catttttaca gtttttcgag aaaattggga
//
